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Company Catalog Company Catalog (20150210) IntuitiveMediCorp,Inc’s products are manufactured using our patented BIOFIT™ Technology. This unique formulation and process provides the optimal balance of the properties that matter most to physicians – strength to preserve the integrity of the wound closure and unmatched flexibility for patient comfort and physician control. BIOFIT™ Product Info DESCRIPTION High viscosity BIOFIT™ Topical Skin Glue is a sterile, liquid topical skin Glue containing a monomeric (2-octyl cyanoacrylate) formulation and the colorant . It is provided in a single use applicator packaged in a blister pouch. The applicator is comprised of a crushable plastic ampule contained within a plastic vial with attached applicator tip. The product is also available with a pen applicator. As applied to skin, the liquid is syrup-like in viscosity and polymerizes within minutes. In vitro studies have shown that high viscosity BIOFIT™ Glue acts as a barrier to microbial penetration as long as the Glue film remains intact. High viscosity BIOFIT™ Glue is different from the regular, or low viscosity BIOFIT™ Glue due to the increased viscosity of the liquid Glue formulation. Low viscosity BIOFIT™ Glue has a viscosity slightly greater than water, while high viscosity BIOFIT™ Glue has a syrup-like viscosity. The increased viscosity of high viscosity BIOFIT™ Glue is intended to reduce the risk of unintended placement of the Glue during application due to migration of the liquid Glue from the wound site. INDICATIONS High viscosity BIOFIT™ Topical Skin Glue is intended for topical application only to hold closed easily approximated skin edges of wounds from surgical incisions, including punctures from minimally invasive surgery, and simple, thoroughly cleansed, trauma-induced lacerations. High viscosity BIOFIT™ Glue may be used in conjunction with, but not in place of, deep dermal stitches. INDICATIONS BIOFIT™ Topical Skin Glue is intended for topical application only to hold closed easily approximated skin edges of wounds from surgical incisions, including punctures from minimally invasive surgery, and simple, thoroughly cleansed, trauma-induced lacerations. BIOFIT™ Glue may be used in conjunction with, but not in place of, For information on availability on IntuitiveMediCorp,Inc’s products in your area or how to order IntuitiveMediCorp,Inc’s products, please contact [email protected] Clinical Education IntuitiveMediCorp,Inc’s researchers are working closely with wound care specialists to develop a program to train doctors and clinicians in the proper use of IntuitiveMediCorp,Inc’s cyanoacrylate-based Glue products. Please check this our site(www.intuitivemedicorp.com) periodically for updates on our training programs and literature. Description Product Code Fill Volume(ml) Packaging Remarks BIOFIT™ BFCB001 0.5 10Applicators Topical Skin per Box Glue BiOFiT Topical Skin Adhesive Manual DESCRIPTION High viscosity BiOFiT Topical Skin Adhesive is a sterile, liquid topical skin adhesive containing a monomeric (2-octylcyanoacrylate) formulation. It is provided in a single use applicator packaged in a blister pouch. The applicator is comprised of HDPE applicator contained within a plastic vial with attached applicator tip. As applied to skin, the liquid is syrup-like in viscosity and polymerizes within minutes. In vitro studies have shown that high viscosity BiOFiT adhesive acts as a barrier to microbial penetration as long as the adhesive film remains intact. Clinical studies were not conducted to demonstrate microbial barrier properties. INDICATIONS High viscosity BiOFiT Topical Skin Adhesive is utilized for topical application only to hold closed easily approximated skin edges of wounds from surgical incisions, including punctures from minimally invasive surgery, and simple, thoroughly cleansed, trauma-induced lacerations. High viscosity BiOFiT adhesive may be used in conjunction with, but not in place of deep dermal stitches. CONTRADITIONS • Do not use on any wound with evidence of active infection, gangrene, or wounds of decubitis etiology. • Do not use on mucosal surfaces or across mucocutaneous junctions (e.g., oral cavity, lips), or on skin which may be regularly exposed to body fluids or with dense natural hair,(e.g.,scalp). • Do not use on patients with a known hypersensitivity to cyanoacrylate or formaldehyde. WARNINGS Solvents such as acetone should be avoid. BiOFiT should not be applied to wet wounds. BiOFiT should not be applied to eye. When it occurs : flush the eye with saline or water. BiOFiT should not be used below the skin due to non absorption by skin or eliciting a foreign body reaction. BiOFiT should not be used in high skin tension. BiOFiT should not be used on wound sight that is to be subjected to repeated or continual moisture or friction. BiOFiT should be used after wounds have been cleaned. BiOFiT should be packaged and utilized for single use only. Discard remaining opened material. Do not resterilize BiOFiT adhesive. Do not apply liquid or ointment medication or other substances to the wound after close with BiOFiT adhesive. If unintended bonding of intact skin occurs ‘Petroleum jelly or acetone may help loosen the bond. Other agents such as water, saline’. Keep away from children. Check the adhesive validation time. (recommendable two years after production) Do not swallow adhesive. Keep the adhesive below room temperature. Keep away from the direct sunlight. To use applicator, hold the body without gripping the cap and twist the cover Keep refrigerated to use longer period Multiple and thin application to proceed polymerization Manufacturer : IntuitiveMediCorp, Inc. 105, Saneopdanji-gil, Pungsan-eup, Andong-si, Gyeongsangbuk-do, Rep of Korea KFDA License Number 14-506 Picture can be changeable according company’s decision at any time. To Place An Order: E-mail: [email protected] Phone: +82(0)548235250 Fax: +82(0)548235251 BIOFIT™ Atomic Force Microscope picture Product under the sales PRODUCT 2-OCA* Hydroxy B-TCP GELATIN Apatite ` Dental Filler 50% 40% 10% Anti Adhesion 50% 50% Barrier Bone Cement 70% 30% Hemostat 80% 20% Synthetic 50% 40% 10% Bone ` Patent_Registered(http://kpa.kipris.or.kr/kpa/search/search_kpa.do) 시아노아크릴레이트계 생체 접착제 조성물(Cyanoacrylate-based tissue adhesive composition) CYANOACRYLATE-BASED TISSUE ADHESIVE COMPOSITION, WHICH USES POLY OCTYL CYANOACRYLATE AND 3,5-DIIODINE-4-PYRIDONE-1-ACETIC ACID PURPOSE: A cyanoacrylate-based tissue adhesive composition is provided to enhance biodegradation property and antimicrobial efficiency. CONSTITUTION: A cyanoacrylate-based tissue adhesive composition comprises poly octyl cyanoacrylate and 3,5-diiodine-4-pyridone-1-acetic acid. The poly octyl cyanoacetate is prepared as follows. The octyl cyanoacetate is prepared by reacting cyanoacetic acid and octane alcohol at 1:1 equivalence ratio. The octyl cyanoacetate and paraformaldehyde are reacted at 1:1 equivalence ratio. The octyl cyanoacrylate is separated and refined after eliminating solvent if the reaction is completed. The poly octyl cyanoacrylate is obtained from by-product in which octyl cyanoacrylate is refined. COPYRIGHT KIPO 2012 Cyano-acrylate-based adhesive composition vivo The present invention relates cyano-acrylate adhesive composition vivo using biodegradable poly-octyl Montepulciano that is generated as a by-product during the manufacture acrylate Ano than as a thickener when octyl acrylate, as anionic stabilizers increase By using 3,5-die-iodine, 4-flute money-1-acetic acid (3,5-diiodo-4-pyridone-1-actetic acid) excellent antimicrobial efficacy, cyano acrylate adhesive composition vivo. Damaged tissue by a simple operation on behalf of the suture, tissue adhesive bonding is very useful state-of-the-art medical supplies. Generally want to join the organization because it is wet in the blood or body fluids, and difficult to obtain sufficient adhesion only in limited, so possess characteristics such as fast adhesive properties and biocompatibility has been used. Double fibrin glue (fibrin glue) and cyanoacrylate glue (cyanoacrylate) is closest to the practicality ofFibrinogen (fibrinogen), fibrin glue and thrombin (thrombin) and calcium chloride (calcium chloride) is composed of the expression of adhesion by the reaction between them. Separation are manufactured from human plasma fibrinogen However, there are disadvantages that are likely to be infected with the virus. The fibrin glue used in many different areas but excellent hemostatic properties and tissue regeneration compared with cyanoacrylate glue, adhesive strength decreases, Cyanoacrylate adhesive cyanoacrylate ester monomer as the original superglue known. Instantaneous polymerization of the anionic polymerization under a weak base, such as water or an amine as a colorless liquid. The long alkyl ester cyanoacrylate compared to a short molecular chain the Montepulciano methyl acrylate, exploded views, and excellent adhesion of the blood Gunn On the other hand, no Shia recently gained FDA approval octyl acrylate (trade name: Dermabond), the hydrolysis of the Montepulciano methyl acrylate, causing inflammation, toxic formaldehyde generated by fast expanding applied as a tissue adhesive has excellent histocompatibility is expected to be However, when octyl Ano acrylate production yield is low and most expensive, and sold them for commercial use, there are many restrictions. Cyano-acrylate adhesive, cost-effective efforts to manufacture the biodegradable and antibacterial activity with excellent results, the inventors of the present invention
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