DOCSLIB.ORG

Klinik Psikiyatri Dergisi

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Klinik Psikiyatri Dergisi ISSN1302-0099/e-ISSN2146-7153 KLÝNÝKPSÝKÝYATRÝDERGÝSÝ KLÝNÝK www.klinikpsikiyatri.org DERGÝSÝ Yil/Year2019Cilt/Volume22Sayi/Number1 Yýl / Year: 2019 Cilt / Volume: 22 KLÝNÝK PSÝKÝYATRÝ DERGÝSÝ Sayý Number 1 ANP Yayýncýlýk www.klinikpsikiyatri.org KLÝNÝK DERGÝSÝ ISSN:1302-0099/eISSN:2146-7153 Yýl:2019Cilt:22Sayý:1 Ýçindekiler/Contents Editörden/ Editorial 5 Editör’den MehmetYumru AraþtýrmaYazýlarý ResearchArticles 7 Sosyalanksiyetebozukluðu'ndadürtüsellikveanksiyeteduyarlýlýðýözelliklerininhastalýkþiddetiileiliþkisi Therelationshipsamongimpulsivity,anxietysensitivitycharacteristics,andseverityofsocialanxietydisorder SafiyeBaharÖlmez,AhmetAtaoðlu 16 Þizofrenihastalarýnabakýmverenlerinbakýmyüklerininyaþamkalitesineetkisininincelenmesi Investigationoftheeffectbetweencareburdenandqualityoflifeincaregiversofschizophreniapatients HakanKaraaðaç,EsraÇalýkVar 27 Postmenopozaldönemdekikadýnlardapsikolojikbelirtilervecinselyaþamýnincelenmesi:Kesitselçalýþma Analysisofpsychologicalfactorsandsexuallifeinpostmenopausalwomen:Across-sectionalstudy SerenAkman,MehmetÇakýcý,BuseKeskindað,MeryemKaraaziz 36 Acilveyoðunbakýmünitesiçalýþanlarýndatravmasonrasýstresbozukluðu,tükenmiþlikvebaþetmebiçimlerinin deðerlendirilmesi Evaluationofpost-traumaticstressdisorder,burnoutandcopingstylesinemergencyandintensivecareunitemployees ErkanBaysak,MelihaZenginEroðlu,ÇisemUtku,BurhanettinKaya 48 Bipolarbozukluktanýlýhastalardacinseliþlevlerveprolaktindüzeyleri Sexualfunctionsandprolactinlevelsinpatientswithbipolardisorder RabiaNazikYüksel,ElifTatlýdilYaylacý,HasanKaya,GamzeErzin,EmineMerveAkdað,AdemDemirci,ÇiðdemAydemir,ErolGöka 57 Birtýpfakültesindeöðrenimgörmekteolanöðrencilerinruhsalbozukluklarayöneliktutumlarý Amedicalschoolstudents'mentaldisordersattitudes FerdiKöþger,AliErcanAltýnöz 63 Özgülduygulartemelliduygudüzenlemebecerileriölçeði’ninTürkçe’yeuyarlanmasý:Geçerlikvegüvenirlikçalýþmasý Turkishadaptationofemotionregulationskillsquestionnaire-emotionspecific:Thestudyofreliabilityandvalidity SevginarVatan 71 Liseöðrencisiergenlerinsuçayöneliktutumlarýveriskfaktörleri Theattitudesofhighschooladolescenttowardcrimeandriskfactors EzgiSarý,HülyaArslantaþ 83 8-12yaþarasýçocuklardabilgisayaroyunbaðýmlýlýðý,aleksitimi,sosyalanksiyete,yaþvecinsiyetinincelenmesi Examinationcomputergamingaddiction,alexithymia,socialanxiety,ageandgenderamongchildrenaged8-12 ÝbrahimTaþ,ZehraGüneþ 93 Liseöðrencilerininçocuklukçaðýörselenmeyaþantýlarýilebiliþselçarpýtmaveyalnýzlýkeðilimleriarasýndakiiliþki Relationshipbetweenchildhoodabuseexperiences,cognitivedistortionsandlonelinesslevelsofhighschoolstudents TuðbaTürkkan,HaticeOdacý Derleme Review 104 Kendiliðinnöralaltyapýsý:NorthoffveDamasiomodelleri Neuralcorrelatesofself:ModelsofNorthoffandDamasio ZahideTepeliTemiz,LütfüHanoðlu EditöreMektup LettertoEditor 116 Opioidkullanýmýileiliþkiliduodenalperforasyon Duodenalperforationinapatientwithheroinuse ÜmitHalukYeþilkaya,YasinHasanBalcioglu,MehmetCemIlnem 1 YAZIMKURALLARI Klinik Psikiyatri Dergisi, Psikiyatri, Klinik Psikoloji, verilerin toplanmasýna, analiz edilmesine ve yorumlanmasýna Psikofarmakoloji ve Nörolojinin psikiyatriyi ilgilendiren önemli katký saðlamýþ olmak; alanlarýnda yapýlan deneysel ve klinik araþtýrmalar, derlemeler, 2. Yazý taslaðýný hazýrlamýþ ya da önemli fikirsel içeriðin eleþtirel olgu sunumlarý, kýsa bildiriler ve editöre mektup türünden incelemelerini yapmýþ olmak; yazýlara yer vermektedir. Yýlda 4 kez yayýnlanan dergi, Türkçe ve Ýngilizce yazýlarý kabul etmektedir. 3. Yazýnýn yayýndan önceki son halini gözden geçirmiþ ve onaylamýþ olmak; Gönderilen makaleler için; iletim, deðerlendirme, yayýnlanma gibi hiçbir aþamada ücret talep edilmemektedir. 4. Çalýþmanýn herhangi bir bölümünün geçerliliði ve doðruluðuna iliþkin sorularýn uygun þekilde 2016 sayýlarý itibari ile makalelere DOI numaralarý verilmektedir. soruþturulduðunun ve çözümlendiðinin garantisini vermek Digital Object Identifier (DOI) sistemi digital ortamda yer alan amacýyla çalýþmanýn her yönünden sorumlu olmayý kabul içeriðe kolay eriþilebilmesini saðlayan bir sistemdir. DOI etmek. numarasý almýþ makaleler ile sistem, basili mecrada yayýnlanmasýna gerek kalmadan çevrimiçi yayýnlanmasý ile Yazarlar bu dört kuralý karþýladýklarýna dair yazýlý onayý Yayýn birlikte çalýþmalarýnýz arasýnda yer almasýný olanak Hakký Devir Formu'nda bildirmek durumundadýr. Dört kriterin sunmaktadýr. Bu durum akademisyenler için zaman açýsýndan hepsini karþýlamayan kiþilere makalenin baþlýk sayfasýnda avantaj saðlamaktadýr. DOI sistemi, ISO standardý olup teþekkür edilmelidir. Yayýn Kurulu'nun gönderilen bir makalede International DOI Foundation tarafýndan idare edilmektedir. “armaðan yazarlýk” olduðundan þüphelenmesi durumunda DOI Sisteminde yer alan dergimizde çalýþmalarý yayýnlanan söz konusu makale deðerlendirme yapýlmaksýzýn yazarlar çalýþmalarýný ulusal ve uluslararasý bilim çevrelerinin reddedilecektir. hýzlý eriþimine sunmakta ve böylelikle yazýlarýnýn atýf Yazarlar, çalýþmalarýndaki doðrudan ya da ticari baðlantý, potansiyelini artýrmaktadýrlar. maddi destek gibi konularda tam olarak açýk olmalýdýrlar. Dergimiz Journal Agent ara yüzü ile makale gönderimi ve takibi Yazarlar bu türden bir iliþkileri varsa bunun nasýl bir iliþki yapmaktadýr. Kullanýcýlar tarafýndan kolay ve hýzlý kulaným olduðunu bildirmek, yoksa hiçbir iliþkileri olmadýðýný belirtmek imkâný tanýyan makale takip sistemi ile çalýþmalarýnýz hýzlý bir zorundadýrlar. Dergimiz,WAME 'in çýkar çatýþmasý tanýmýný þekilde deðerlendirilmektedir. benimsemektedir. Yazýlarýn deðerlendirme süreci ve etik konular Yazýlarýn geliþ tarihleri ve kabul ediliþ tarihleri makalenin yayýnlandýðý sayýda belirtilir. Derginin internet sayfasýnda Klinik Psikiyatri Dergisi makalelerin deðerlendirilmesinde bütün makalelerin Türkçe ve Ýngilizce özet versiyonlarý ile baðýmsýz, tarafsýz, çift-kör hakem deðerlendirme raporlarýný gönderilen dildeki tam metin versiyonlarý bulunur. Ýçerik, yayýn temel alýnmaktadýr. Gönderilen makalelerin özgünlükleri, sürecinin tamamlanmasýný takiben derginin internet metodolojileri, tartýþýlan konunun önemi, Yayýn Kurulu üyeleri sayfasýnda ücretsiz eriþime açýk hale getirilir. Eðer abone deðil tarafýndan deðerlendirilir. Takiben, tarafsýz deðerlendirme iseler yazarlara, yazýlarýnýn yayýnlandýðý dergi sürecinisaðlamakiçinhermakalealanlarýndauzmanenaziki gönderilmemektedir. dýþ-baðýmsýz hakem tarafýndan deðerlendirilir. Bütün makalelerin karar verme süreçlerinde nihai karar yetkisi Dergimizde yayýnlanan yazýlarýn yayýn hakký ANP Özel Saðlýk Editörler Kurulu'ndadýr. Hizmetleri LTD ÞTÝ'ne aittir. Yazarlara telif ücreti ödenmemektedir. Gözden geçirenler yazarlarýn kimliðinden habersizdir ve yazarlar da gözden geçirenlerin kimliðinden habersizdirler. Yayýnlanan yazýlarýn bilimsel ve hukuki sorumluluðu yazarlarýna aittir. Dergide yayýnlanan makalelerde ifade edilen görüþler ve Gönderilen yazýlar, isimleri gizli tutulan konuyla ilgili en az iki fikirler Klinik Psikiyatri Dergisi, Editörler ve Yayýn Kurulu'nun danýþma kurulu üyesince deðerlendirilir. Danýþma kurulunca deðil, yazar(lar)ýn bakýþ açýlarýný yansýtýr. Editörler, Yayýn Kurulu deðerlendirmeleri tamamlanan yazýlar yayýn kurulunda ve Yayýncý bu gibi durumlar için hiçbir sorumluluk ya da görüþülür. Yayýn kurulu yazýyý yayýnlamaya, düzeltilmesi için yükümlülük kabul etmemektedir. geri göndermeye, düzelterek yayýnlamaya ya da yayýnlamamaya yetkilidir. Dergimizin editöryel ve yayýn Gönderilen yazýlarýn hemen iþleme konulabilmesi için belirtilen süreçleri International Committee of Medical Journal Editors yazým kurallarýna tam olarak uygun olmasý gereklidir. (ICMJE), World Association of Medical Editors (WAME), Council Yazým Kurallarý of Science Editors (CSE), Committee on Publication Ethics Dergide yayýnlanmak üzere gönderilen yazýlarýn uzmanlarca (COPE), European Association of Science Editors (EASE) ve tarafsýz deðerlendirmeye alýnabilmesi için, yazarlarýn National Information Standards Organization (NISO) kimliklerine iliþkin bilgilerin, yazýnýn baþýnda yer alacak ayrý bir organizasyonlarýnýn kýlavuzlarýna uygun olarak sayfada bulunmasý gereklidir. biçimlendirilmiþtir. Yazýlar, yazýnýn daha önce bir dergide yayýnlanmamýþ veya Derginin editöryel ve yayýn süreçleri, Principles of Transparency yayýnlanmak üzere gönderilmemiþ, olduðunu bildiren ve tüm and Best Practice in Scholarly Publishing yayýn haklarýnýn ANP Özel Saðlýk Hizmetleri LTD ÞTÝ'ne (doaj.org/bestpractice )ilkelerineuygunolarak devredildiði belirtilen, yazarlarca imzalanmýþ bir üst yazý ile yürütülmektedir. gönderilmelidir. Yayýn Kurulu, dergimize gönderilen çalýþmalar hakkýndaki Yazýlarýnýzý web anasayfamýzda yer alan "online makale gönder" intihal, atýf manipülasyonu ve veri sahteciliði iddia ve þüpheleri butonuna týklayarak gönderebilirsiniz. Her türlü sorunuz için karþýsýndaCOPE kurallarýna uygun olarak hareket edecektir. [email protected] adresinden bize ulaþabilirsiniz. Bütün makalelerin benzerlik tespiti denetimi, iThenticate Ýlk sayfada, makale baþlýðýnýn altýnda, yazarlarýn isim, soyadý, yazýlýmý aracýlýðýyla yapýlmaktadýr unvan, çalýþma adresleri ve varsa e-mail adresleri belirtilmelidir. Eðer makalede daha önce yayýnlanan makalelerden alýntý varsa, En sonda da yazýþmalarýn yapýlacaðý sorumlu yazarýn adres, makalenin yazarý yayýn hakký sahibi ve yazarlarýndan yazýlý onay telefon ve e-mail adresi yer almalýdýr. almak ve bunu makalesinde belirtmek zorundadýr. Alýnan onay belgesi makaleyle beraber editörlüðümüze gönderilmelidir. Araþtýrmalar, olgu sunumlarý ve derleme yazýlarý için Türkçe Hakemlerin, mükerrer yayýn, intihal
Load more

Recommended publications
  • Endogenous Opioid Analgesia in Peripheral Tissues and the Clinical Implications for Pain Control
    REVIEW Endogenous opioid analgesia in peripheral tissues and the clinical implications for pain control Daniel Kapitzke1,2 Abstract: Opioid receptors are widely expressed in the central and peripheral nervous system Irina Vetter1,2 as well as in numerous nonneuronal tissues. Both animal models and human clinical data Peter J Cabot2 support the involvement of peripheral opioid receptors in analgesia, particularly in inflammation where both opioid receptor expression and efficacy are increased. Immune cells have been 1 These authors contributed equally β to this work. 2School of Pharmacy, shown to contain numerous opioid peptides such as -endorphin (END), met-enkephalin University of Queensland, 4072, (ENK), and dynorphin-A (DYN), although the predominant opioid peptide involved in immune- Australia cell mediated antinociception is thought to be END. These opioid-containing immune cells migrate to inflamed tissues during a complex process of recruitment by chemokines, adhesion, and extravasation. In these tissues, opioid peptide is released from the immune cells upon stimulation with corticotrophin-releasing factor (CRF), noradrenaline, and interleukin 1β (IL-1β), and the immune cells return to the local lymph node depleted of peptide. Consistent with this model, systemic immunosuppression may lead to impaired endogenous analgesia as competent immune cells are essential to achieve release of endogenous opioid peptides within inflamed tissue. A further level of complexity is added by the observation that exogenous opioids may impair immune cell function, although there is some evidence to suggest that endogenous opioid peptides do not share this immunosuppressive effect. Improving our understanding of endogenous opioid mechanisms will provide valuable insight towards the development of novel treatments for pain with improved side effect profiles.
    [Show full text]
  • The Use of Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances
    WHO/PSM/QSM/2006.3 The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances 2006 Programme on International Nonproprietary Names (INN) Quality Assurance and Safety: Medicines Medicines Policy and Standards The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances FORMER DOCUMENT NUMBER: WHO/PHARM S/NOM 15 © World Health Organization 2006 All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail: [email protected]). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters.
    [Show full text]
  • Advice Concerning the Addition of Certain Pharmaceutical Products
    U.S. International Trade Commission COMMISSIONERS Daniel R. Pearson, Chairman Shara L. Aranoff, Vice Chairman Jennifer A. Hillman Stephen Koplan Deanna Tanner Okun Charlotte R. Lane Robert A. Rogowsky Director of Operations Karen Laney-Cummings Director of Industries Address all communications to Secretary to the Commission United States International Trade Commission Washington, DC 20436 U.S. International Trade Commission Washington, DC 20436 www.usitc.gov Advice Concerning the Addition of Certain Pharmaceutical Products and Chemical Intermediates to the Pharmaceutical Appendix to the Harmonized Tariff Schedule of the United States Investigation No. 332--476 Publication 3883 September 2006 This report was prepared principally by Office of Industries Philip Stone, Project Leader With assistance from Elizabeth R. Nesbitt Primary Reviewers David G. Michels, Office of Tariff Affairs and Trde Agreements, John Benedetto, and Nannette Christ, Office of Economics Administrative Support Brenda F. Carroll Under the direction of Dennis Rapkins, Chief Chemicals and Textiles Division ABSTRACT Under the Pharmaceutical Zero-for-Zero Initiative, which entered into force in 1995, the United States and its major trading partners eliminated tariffs on many pharmaceuticals, their derivatives, and certain chemical intermediates used to make pharmaceuticals. The U.S. list of pharmaceutical products and chemical intermediates eligible for duty-free treatment under the agreement is given in the Pharmaceutical Appendix to the Harmonized Tariff Schedule of the United States. The Pharmaceutical Appendix is periodically updated to provide duty relief for additional such products, including newly developed pharmaceuticals. This report provides advice on the third update to the agreement, in which approximately 1,300 products are proposed to receive duty-free treatment.
    [Show full text]
  • (12) United States Patent (10) Patent No.: US 9,708.371 B2 Kessler Et Al
    USOO9708371B2 (12) United States Patent (10) Patent No.: US 9,708.371 B2 Kessler et al. (45) Date of Patent: Jul.18, 2017 (54) TREATMENTS FOR GASTROINTESTINAL 5,654,278 A 8/1997 Sorensen DSORDERS 5,904,935 A 5/1999 Eckenhoff et al. 6,068,850 A 5, 2000 Stevenson et al. 6,124,261 A 9, 2000 Stevenson et al. (75) Inventors: Marco Kessler, Danvers, MA (US); 6,541,606 B2 4/2003 Margolin et al. Angelika Fretzen, Somerville, MA 6,734,162 B2 5/2004 Van Antwerp (US); Hong Zhao, Lexington, MA 6,828.303 B2 12/2004 Kim et al. (US); Robert Solinga, Brookline, MA 36.3% E: 1339. SN. (US); Vladimir Volchenok, Waltham, 7,056,942- - - B2 6/2006 HildesheimOK et al. MA (US) 7,141,254 B2 11/2006 Bhaskaran et al. 7,304,036 B2 * 12/2007 Currie .................. CO7K 14,245 (73) Assignee: Ironwood Pharmaceuticals, Inc., 514,122 Cambridge, MA (US) 7.351,798 B2 4/2008 Margolin et al. 7,371,727 B2 5/2008 Currie et al. (*)c Notice:- r Subject to any disclaimer, the term of this 7,704,9477,494,979 B2 4/20102/2009 Currie et al. patent is extended or adjusted under 35 7,745,409 B2 6/2010 Currie et al. U.S.C. 154(b) by 364 days. (Continued) (21) Appl. No.: 14/239,178 FOREIGN PATENT DOCUMENTS (22) PCT Filed: Aug. 17, 2012 JP 64-009938 1, 1989 JP 2003-2012.56 T 2003 (86). PCT No.: PCT/US2012/051289 (Continued) S 371 (c)(1), (2), (4) Date: Nov.
    [Show full text]
  • (12) United States Patent (10) Patent No.: US 8,158,152 B2 Palepu (45) Date of Patent: Apr
    US008158152B2 (12) United States Patent (10) Patent No.: US 8,158,152 B2 Palepu (45) Date of Patent: Apr. 17, 2012 (54) LYOPHILIZATION PROCESS AND 6,884,422 B1 4/2005 Liu et al. PRODUCTS OBTANED THEREBY 6,900, 184 B2 5/2005 Cohen et al. 2002fOO 10357 A1 1/2002 Stogniew etal. 2002/009 1270 A1 7, 2002 Wu et al. (75) Inventor: Nageswara R. Palepu. Mill Creek, WA 2002/0143038 A1 10/2002 Bandyopadhyay et al. (US) 2002fO155097 A1 10, 2002 Te 2003, OO68416 A1 4/2003 Burgess et al. 2003/0077321 A1 4/2003 Kiel et al. (73) Assignee: SciDose LLC, Amherst, MA (US) 2003, OO82236 A1 5/2003 Mathiowitz et al. 2003/0096378 A1 5/2003 Qiu et al. (*) Notice: Subject to any disclaimer, the term of this 2003/OO96797 A1 5/2003 Stogniew et al. patent is extended or adjusted under 35 2003.01.1331.6 A1 6/2003 Kaisheva et al. U.S.C. 154(b) by 1560 days. 2003. O191157 A1 10, 2003 Doen 2003/0202978 A1 10, 2003 Maa et al. 2003/0211042 A1 11/2003 Evans (21) Appl. No.: 11/282,507 2003/0229027 A1 12/2003 Eissens et al. 2004.0005351 A1 1/2004 Kwon (22) Filed: Nov. 18, 2005 2004/0042971 A1 3/2004 Truong-Le et al. 2004/0042972 A1 3/2004 Truong-Le et al. (65) Prior Publication Data 2004.0043042 A1 3/2004 Johnson et al. 2004/OO57927 A1 3/2004 Warne et al. US 2007/O116729 A1 May 24, 2007 2004, OO63792 A1 4/2004 Khera et al.
    [Show full text]
  • Datasheet Inhibitors / Agonists / Screening Libraries a DRUG SCREENING EXPERT
    Datasheet Inhibitors / Agonists / Screening Libraries A DRUG SCREENING EXPERT Product Name : Frakefamide Catalog Number : T11323L CAS Number : 188196-22-7 Molecular Formula : C30H34FN5O5 Molecular Weight : 563.62 Description: Frakefamide is a potent analgesic. It acts as a peripheral active μ-selective receptor agonist. Frakefamide is unable to penetrate the blood-brain-barrier and enter the central nervous system. Storage: 2 years -80°C in solvent; 3 years -20°C powder; Receptor (IC50) Others In vivo Activity Frakefamide yields a dose-dependent increase in morphine appropriate responding to 50% at the highest dose tested (10 μmol/kg) after infusion durations of 2 min. Whereas after 15 min infusions a maximum of 25% morphine appropriate responding was occasioned at 17.5 μmol/kg [1,2]. Reference 1. Modalen AO, et al. A novel molecule (frakefamide) with peripheral opioid properties: the effects on resting ventilation compared with morphine and placebo. Anesth Analg. 2005 Mar;100(3):713-7. 2. Swedberg MD, et al. Drug discrimination: A versatile tool for characterization of CNS safety pharmacology and potential for drug abuse. J Pharmacol Toxicol Methods. 2016 Sep-Oct;81:295-305. FOR RESEARCH PURPOSES ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE. Information for product storage and handling is indicated on the product datasheet. Targetmol products are stable for long term under the recommended storage conditions. Our products may be shipped under different conditions as many of them are stable in the short-term at higher or even room temperatures. We ensure that the product is shipped under conditions that will maintain the quality of the reagents.
    [Show full text]
  • Duodenal Perforation in a Patient with Heroin Use
    LETTER TO EDITOR Duodenal perforation in a patient with heroin use Opioid kullanýmý ile iliþkili duodenal perforasyon Ümit Haluk Yeþilkaya1, Yasin Hasan Balcýoðlu2, Mehmet Cem Ýlnem3 1M.D., 2M.D.,3Assoc. Prof., Department of Psychiatry, Bakirkoy Prof Mazhar Osman Training and Research Hospital for Psychiatry, Neurology, and Neurosurgery, Istanbul, Turkey 1https://orcid.org/0000-0001-8521-1613 2https://orcid.org/0000-0002-1336-1724 3https://orcid.org/0000-0003-4127-1627 SUMMARY ÖZET A number of vascular pathologies are attributed to the Yoðun opioid kullanýmý miyokardiyal enfarktüs, iskemik opiate exposure such as myocardial infarction, ischaemic inme ve gastrointestinal sistemin hipoperfüzyonu gibi stroke, and hypoperfusion of the gastrointestinal tract. bazý vasküler patolojilere sebep olur. Burada, bilinen her- Here we presented a 30-year-old male patient with no hangi bir iskemik veya gastrointestinal hastalýk öyküsü history of any ischemic or gastrointestinal disease known olmayan 30 yaþýnda bir erkek hastanýn 10 yýllýk yoðun to have 10-year opioid use and had suffered a duodenal opioid kullanýmý sonrasý meydana gelen duedonal per- perforation. Prolonged exposure of opioids may lead to forasyon vakasýný sunduk. Opioidlere uzun süre maruz hypersensitivity reactions, ischemia and hypoperfusion kalýnmasý hipersensitivite reaksiyonlarýna, iskemi ve and combination of these entities with opioid-related hipoperfüzyona neden olabilir. Ayrýca buna opioid ile gastrointestinal motility deficits could contribute to the iliþkili gastrointestinal motilite bozukluklarýnýn eklenmesi epithelial damage and perforation as a consequence. de epitel hasarýna ve perforasyona katkýda bulunabilir. The presence of ischemic events should be kept in mind Yoðun eroin kullanan kiþilerde gastrointestinal semptom- in the presence of gastrointestinal symptoms in people larýn varlýðýnda iskemik olaylarýn varlýðý akýlda tutul- using intensive heroin.
    [Show full text]
  • Stembook 2018.Pdf
    The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances FORMER DOCUMENT NUMBER: WHO/PHARM S/NOM 15 WHO/EMP/RHT/TSN/2018.1 © World Health Organization 2018 Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence (CC BY-NC-SA 3.0 IGO; https://creativecommons.org/licenses/by-nc-sa/3.0/igo). Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercial purposes, provided the work is appropriately cited, as indicated below. In any use of this work, there should be no suggestion that WHO endorses any specific organization, products or services. The use of the WHO logo is not permitted. If you adapt the work, then you must license your work under the same or equivalent Creative Commons licence. If you create a translation of this work, you should add the following disclaimer along with the suggested citation: “This translation was not created by the World Health Organization (WHO). WHO is not responsible for the content or accuracy of this translation. The original English edition shall be the binding and authentic edition”. Any mediation relating to disputes arising under the licence shall be conducted in accordance with the mediation rules of the World Intellectual Property Organization. Suggested citation. The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances. Geneva: World Health Organization; 2018 (WHO/EMP/RHT/TSN/2018.1). Licence: CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data.
    [Show full text]
  • Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
    (19) TZZ ¥__T (11) EP 2 998 314 A1 (12) EUROPEAN PATENT APPLICATION (43) Date of publication: (51) Int Cl.: 23.03.2016 Bulletin 2016/12 C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61K 47/48 (2006.01) A61P 1/00 (2006.01) (21) Application number: 15190713.6 (22) Date of filing: 04.06.2008 (84) Designated Contracting States: (72) Inventors: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR • SHAILUBHAI, Kunwar HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT Audubon, PA 19402 (US) RO SE SI SK TR • JACOB, Gary S. New York, NY 10028 (US) (30) Priority: 04.06.2007 US 933194 P (74) Representative: Cooley (UK) LLP (62) Document number(s) of the earlier application(s) in Dashwood accordance with Art. 76 EPC: 69 Old Broad Street 12162903.4 / 2 527 360 London EC2M 1QS (GB) 08770135.5 / 2 170 930 Remarks: (71) Applicant: Synergy Pharmaceuticals Inc. This application was filed on 21-10-2015 as a New York, NY 10170 (US) divisional application to the application mentioned under INID code 62. (54) AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS, INFLAMMATION, CANCER AND OTHER DISORDERS (57) The invention provides novel guanylate cycla- esterase. The gastrointestinal disorder may be classified se-C agonist peptides and their use in the treatment of as either irritable bowel syndrome, constipation, or ex- human diseases including gastrointestinal disorders, in- cessive acidity etc. The gastrointestinal disease may be flammation or cancer (e.g., a gastrointestinal cancer).
    [Show full text]
  • Target and Suspect Screening of Contaminants of Emerging Concern in Raw Water and Drinking Water from Europe and Asia
    Water Research 198 (2021) 117099 Contents lists available at ScienceDirect Water Research journal homepage: www.elsevier.com/locate/watres What’s in the water? –Target and suspect screening of contaminants of emerging concern in raw water and drinking water from Europe and Asia ∗ Rikard Tröger a, , Hanwei Ren b, Daqiang Yin b, Cristina Postigo c, Phuoc Dan Nguyen d, Christine Baduel e, Oksana Golovko a,f, Frederic Been g, Hanna Joerss h, Maria Rosa Boleda i, Stefano Polesello j, Marco Roncoroni k, Sachi Taniyasu l, Frank Menger a, Lutz Ahrens a, Foon Yin Lai a, Karin Wiberg a a Department of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences (SLU), Box 7050, SE-750 07 Uppsala, Sweden b Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 20 0 092, China c Water, Environmental, and Food Chemistry Unit (ENFOCHEM), Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research (IDAEA-CSIC), Carrer Jordi Girona 18-26, Barcelona, 08034, Spain d Centre Asiatique de Recherche sur l’Eau, Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet, District 10; Vietnam National University of Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Vietnam e Université Grenoble Alpes, IRD, CNRS, Grenoble INP, IGE, 38 050 Grenoble, France f University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture
    [Show full text]
  • Customs Tariff - Schedule
    CUSTOMS TARIFF - SCHEDULE 99 - i Chapter 99 SPECIAL CLASSIFICATION PROVISIONS - COMMERCIAL Notes. 1. The provisions of this Chapter are not subject to the rule of specificity in General Interpretative Rule 3 (a). 2. Goods which may be classified under the provisions of Chapter 99, if also eligible for classification under the provisions of Chapter 98, shall be classified in Chapter 98. 3. Goods may be classified under a tariff item in this Chapter and be entitled to the Most-Favoured-Nation Tariff or a preferential tariff rate of customs duty under this Chapter that applies to those goods according to the tariff treatment applicable to their country of origin only after classification under a tariff item in Chapters 1 to 97 has been determined and the conditions of any Chapter 99 provision and any applicable regulations or orders in relation thereto have been met. 4. The words and expressions used in this Chapter have the same meaning as in Chapters 1 to 97. Issued January 1, 2020 99 - 1 CUSTOMS TARIFF - SCHEDULE Tariff Unit of MFN Applicable SS Description of Goods Item Meas. Tariff Preferential Tariffs 9901.00.00 Articles and materials for use in the manufacture or repair of the Free CCCT, LDCT, GPT, following to be employed in commercial fishing or the commercial UST, MXT, CIAT, CT, harvesting of marine plants: CRT, IT, NT, SLT, PT, COLT, JT, PAT, HNT, Artificial bait; KRT, CEUT, UAT, CPTPT: Free Carapace measures; Cordage, fishing lines (including marlines), rope and twine, of a circumference not exceeding 38 mm; Devices for keeping nets open; Fish hooks; Fishing nets and netting; Jiggers; Line floats; Lobster traps; Lures; Marker buoys of any material excluding wood; Net floats; Scallop drag nets; Spat collectors and collector holders; Swivels.
    [Show full text]
  • List of Psychoactive Drug Spirits for MD A-Methylfentanyl, Abilify
    List of Psychoactive Drug Spirits for MD A-Methylfentanyl, Abilify, abnormal basal ganglia function, abuse of medicines, Aceperone, Acepromazine, Aceprometazine, Acetildenafil, Aceto phenazine, Acetoxy Dipt, Acetyl morphone, Acetyl propionyl morphine, Acetyl psilocin, Activation syndrome, acute anxiety, acute hypertension, acute panic attacks, Adderall, Addictions to drugs, Addictions to medicines, Addictions to substances, Adrenorphin, Adverse effects of psychoactive drugs, adverse reactions to medicines, aggression, aggressive, aggressiveness, agitated depression, Agitation and restlessness, Aildenafil, Akuammine, alcohol abuse, alcohol addiction, alcohol withdrawl, alcohol-related brain damage, alcohol- related liver damage, alcohol mix with medicines for adverse reaction, Alcoholism, Alfetamine, Alimemazine, Alizapride, Alkyl nitrites, allergic breathing reactions to meds, choking to anaphallectic shock, & death; allergic skin reactions to meds, rash, itchyness, hives, welts, etc, Alletorphine, Almorexant, Alnespirone, Alpha Ethyltryptamine, Alpha Neoendorphin, alterations in brain hormones, alterations in mental status, altered consciousness, altered mind, Altoqualine, Alvimopan, Ambien, Amidephrine, Amidorphin, Amiflamine, Amisulpride, Amphetamines, Amyl nitrite, Anafranil, Analeptic, Anastrozole, Anazocine, Anilopam, Antabuse, anti anxiety meds, anti dopaminergic activity, anti seizure meds, Anti convulsants, Anti depressants, Anti emetics, Anti histamines, anti manic meds, anti parkinsonics, Anti psychotics, Anxiety disorders,
    [Show full text]