Author Index Page Numbers in Italics Refer to the Bibliography

Author Index Page numbers in italics refer to the bibliography

Abbs, E. T., Broadley, K. J., Ahlquist, R. P., Levy, B. 285, Allegranza, A., see Bozzi, R., Roberts, D. J. 506, 518 298,330 855, 884 - Robertson, M.1. 777, 803 Ahmed, R., see Pullar, I. A. Allen, D. J., Garg, K. N., Mar• Abdulla, Y. H., see Adams, C. 859, 872, 873, 894 ley, E. 491, 492, 493, iH8 W. M. 48, 72 Aigner, A., Hornykiewicz, 0., - Marley, E. 484, 485, 491, Abe, K., Butcher, R. W., Ni• Lisch, H.-J., Springer, A. 509,518 cholson, W. E., Baird, C. 504,518 Allen, D.O., Hillman, C. C., E., Liddle, R. A., Liddle, - see Lisch, H.-J. 148, 179 Ashmore, J. 301, 302, 330, G. W. 434, 441 Aiken, J. W., Reit, E. 662, 715 387,441 Abel, J. J., Crawford, A. C. Akabane, J., Nakanishi, S., Allen, G., see Friesen, A. J. D. 1l0,171 Kohei, H., Asakawa, S., 394,398,447 - De M. Taveau, R. 1l0, 171 Matsumura, R. Ogata, H., Allen, M. L., see Himwich, W. - Macht, D. I. 114, 171 Miyazawa, T. 587, 605 A. 465, 528 Abood, L. G., Koketsu, K., Akawie, R. I., see Hartman, Aim, P., Ehinger, B., Falck, B. Miyamoto, S. 256, 261 W. J. 191, 224, 853, 867, 871,881 Abrams, W. B., Solomon, H. 880,889 Almgren, 0., Anden, N.-E., M. 873,881 Akester, A. R., Mann, S. P. Jonason, J., Norberg,K.-A., - see Leon, A. S. 873, 891 117,171 Olson, L. 752, 756 - see Solomon, H. M. 873, Akimoto, H., see Inoue, M. -- Waldeck, B. 621, 626, 879,897 140,178 652 Abuzzahab, F. S. 495, 518 Alberici, M., Rodriguez de Lo• - Lundborg, P. G., Stitzel, R. Acheson, G. H. 729, 756 res Arnaiz, G., de Robertis, E. 621, 652 - Remolina, J. 689, 715 E. 504, 518 - Waldeck, B. 621, 630, 652 Ackermann, H., see Lange- - see De Robertis, E. 427, 446 Alonso-de Florida, F., see Par• mann, H. 854, 891 Albers, R. W., see Axelrod, J. do, E. G. 783, 811 Adam, P. A. J., Haynes, R. C., 272, 279, 816, 835 Alousi, A., Weiner, N. 194,219 jr. 372, 377, 441 Albert, A. 193, 219, 464, 518 Alper, M. R., see Gillis, R. A. Albores-Saavedra, J., Maldo• 685,718 Adams, C. W. M., Abdulla, Y. nado, M. C., Ibara, J., Ro- - see Krayer, O. 355, 359 H., Bayliss, O. B. 48, 72 driguez, H. A. 909, 924 Alpers, H. S., see Crout, J. R. Adams, W. E. 22, 39 Albrecht, I., see Hruza, Z. 170, 625, 630, 631, 632, 633, 641, Adams-Ray, J. 131,171 178 653 - Dahlstrom, A., Fuxe, K., Alcaraz, A., see Masuoka, D. - see Shore, P. A., 497, 535, Haggendal, J. 25, 39 T. 626, 656 619,621,622,625,628,637, --- Hillarp, N.-A. 133, Aldrich, T. B. 1l0, 171 638,658 171 Aldridge, J., Bradley, P. B. 477 Altland, P. D., see Stern, D. N. - Nordenstam, H. 24, 39 Aldridge, W. N., Street, B. W. 814,842 - see Bloom, G. 18, 40, 113, 411, 412, 441 Altman, M., see Sapira, J. P. 134,172 Alexander, N., see De Quattro, 901,931 - see Ostlund, E. 134, 181 V.194,222 Alton, H., see Goodall, McC. Adanja, 8., see Mi6i6, R. 902, Alexandrowicz, J. S. 100,105 855,888 929 Alfes, H., see Knoche, H. 113, Alvarez, N., see Drujan, B. D. Mzelius, B. A., see Lindberg, 130,179 141,157,174 0.412,453 Algeri, S., see Bloom, F. E. 47, Amador, L. V., see Schwab, R. Agallianos, D., see Messiha, F. 64,67,72 S.863,895 S.855,892 - see Groppetti, A. 857, 888 Amakawa, A., see Shimazu, T. Aghajanian, G. K., Bloom, F. - see Manara, L. 500, 531 370, 371, 459 E. 61, 63, 72 AI-Lami, F. 600, 601, 605 Amalfara, M. L., see Fischer, - see Bloom, F. E. 46, 50, 61, Allan, W., Tepperman, H. M. E. 471, 525 63,64,71,72 422,441 Amar-Costesec, A., Bohuon, C., Agrawal, H. C., Glisson, S. N., Allegra, F., Marcheselli, W. 25, Schweissguth, O. 904, 917, Himwich, W. A. 118, 171 39 924 Ahlquist, R. P. 9, 11, 285, 286, Allegranza, A., Bozzi, R., Bru• - see Bohuon, C. 917, 924 330,814,835 no, A. 236, 261 Ambache, N. 766, 803 Author Index 935

Ambrose, J. M., see Engelman, Anden, N.-E., Norberg, K. A., Anton, A. H., Gennaro, J. F. K. 914, 925 Olson, L. 129,166,171 116, 142,171 Amery, A., Moerman, E. J., - Roos, B. E., Werdinius, B. - Greer, M., Sayre, D. F., BOBBaert, H., de Schaepdry• 498, 518, 519, 855, 859, 881 Williams, C. M., 852, 881, ver, A. F. 627, 652, 916, 924 - see Almgren, O. 621, 626, 905, 911, 913, 918, 924 Amin, A. N., Crawford, T. B. 652,752,756 - Sayre, D. F. 112, 116, 118, B., Gaddum, J. H. 486, 518 - see Ungerstedt, U. 506, 537, 119,131,140,142,144,147, Ammon, H. P. T., see Estier, 854,898 149, 154, 159, 160, 161, 163, C.J.496,524 Andersen, H. T., Andersson, 164, 166, 167,171 Amsterdam, A., Ohad, 1., B., Gale, C. 490, 519 - see Greer, M. 918, 920, 921, Schramm, M. 423, 441, 589, Andersen, S. 0., 85, 109 927 597,605 - Barrett, F. M. 85 Antonaccio, M. J., Smith, C. B. Anagnoste, B., Goldstein, M. Anderson, E. 52, 72 752,756 881 Anderson, E. G., Baker, R. G., Antunes, J. L., Macedo, C., Da• - see Battista, A. F. 847, 882 Banna, N. R. 517, 519 masio, A. R. 862, 881 - see Goldstein, M. 193, 201, - Holgerson, L. O. 119, 154, - see Damasio, A. R. 865, 886 223,501,503,526,628,654, 171 Apelbaum, J., see Segura, E. T. 814,838,847,850,863,874, - see Baker, R. G. 518, 519 115,183 880,887,888,917,926 Anderson, H. K. 832, 835 Appel, W. C., Vincenzi, F. F. - see Musacchio, J. M. 503, Anderson, P. J., D'Iorio, A. 765,803 532 858,881 Appelgren, L. E., see Elfvin, Anah, C. 0., see Ruthven, C. R. AnderBBon, B., Grant, R., Lars• L.-G. 31, 41, 52, 68, 74 J. 874, 894 son, S. 494, 519 Appleman, M. M., Birnbaumer, Anand, B. K. 489, 518 - Jobin, M., Olsson, K. 484, L., Torres, H. N. 401, 404, - Brobeck, J. R. 489, 519 519 441 - Dua, S.489, 519 - Larsson, B. 490, 519 - see Belocopitow, E. 403, 442 Anden, N.-E. 119, 171, 197, - see Andersen, H. T. 490, 519 Applewhite, P. B., Gardner, F. 200,206,219,497,519,619, Andersson, R. G. G., Mohme• T., Lapan, E. 81, 85, 105 625,628,636,637,638,639, Lundholm, E. 406, 441 April, S. A., see Salvador, R. A. 652 Andrews, R. S., Pridham, J. B. 286,334,423,458 - Butcher, S. G., Corrodi, H., 852,881 Aprison, M. H., Takahashi, R. Fuxe, K., Ungerstedt, U. Andrews, W. H. H. 709, 715 144, 147,171 854,881 - see Nasmyth, P. A. 211, Arakowa, T., Wada, Y., Tada, -- Engel, J. 878, 881 227 K., Ito, H. 852, 881 -- Fuxe,K. 878,881 Angel, A., Rogers, K. J. 506, Arana, R., see Leimdorfer, A. - Carlsson, A., Dahlstrom, A., 519 470,471,530 Fuxe, K., Hillarp, N.-A., Angelakos, E. T., Fuxe, K., Archer, S., Arnold, A., Kullnig, Larsson, K. 847, 881 Torchiana, M. L. 125, 159, R. K., Wylie, D. W. 506, -- Kerstell, J., Magnusson, 171, 188, 201, 219 519 T., OIBBon, R., Roos, B. E., - Glassman, P. M., Millard, R. - see Wylie, D. W. 273, 282, Steen, B., Steg, G., Svan• W., King, M. 115, 137, 139, 759,761 borg, A., Thieme, G., Wer• 140,171 Arias, D., see Tamer, A. 848, dinius, B. 865, 866, 872, 874, - King, M., Millard, R.W. 897 875,881 160,171 Ariens, E. J. 288, 289, 302, 323, -- Waldeck, B. 199, 209, - see McKenna, O. C. 126, 330 219 161,180 - see Van Rossum, J. M. 288, - Corrodi, H., Ettles, M., Angeletti, P., Calissano, P., 335 Gustafsson, E., Persson, H. Chen, J. S., Levi-Montalci• Arimura, A., see Couch, E. F. 197, 198, 206, 219, 737, ni, R. 819, 829, 835 563,607 756 - see Levi-Montalcini, R. 11, Armett, C. J., Ritchie, J. M. - Fuxe, K., Hamberger, B., 14, 167, 179, 814, 819, 820, 703,706,715,765,803 Hokfelt, T. 149,171 821, 822, 830, 831, 840 Armitage, P., see CaIne, D. B. -- Henning, M. 641, 642, Angeletti, P. U., see Salvi, M. 861, 865, 873, 884 652 L. 819, 841 - see Hunter, K. R. 869, 870, -- Hokfelt, T. 641, 652 Anlyan, W. G., Hargrove, M. 890 - Henning, M. 157, 171, 236, D., jr., Ruffin, J. M., Wal• Armstrong, M. D., McMillan, A. 261 lace, D. K., Weaver, W. T., 193,219 - Jukes, M. G. M., Lundberg, Kirshner, N. 861, 881 -- Shaw, K. F. 6, 11, 270, A. 518, 519 Ansel, R. D., Markham, C. H. 272,279,848,881,912,924 --- Vyklicky, L, 518,519 863,865,881 - see Kakimoto, Y. 189, 225, - Magnusson, T. 206, 219, - see Markham, C. H. 863, 629,655 495,498,519,625,637,644, 892 - see Shaw, K. N. F. 270, 281, 652 Anthony, P. P., Coles, H. M. T., 874,896 -- Rosengren, E. 813, 816, Pryse-Davies, J., Sinclair, Arner, P., see Ostman, J. 386, 828,835 L. 917, 919, 924 387,455 936 Author Index

Arnold, A., McAuliff, J. P. 320, Auditore, J. V., see Hollett, C. Axelrod. J., see Hertting, G. 321,330,387,440,441 R. 388, 450 198, 202, 208, 209, 212, 213, -- Colella, D. F., O'Connor, Auer, C. M., see Meltzer, S. J. 224,274,280,355,359,500, W. V., Brown, jr., Th. G. 832,840 528, 630, 654, 813, 814, 816, 320,321,330 Augustinsson, K. B., Fange, R., 827,833,838 - Selberis, W. H. 320, 321, Johnels, A., Ostlund, E. - see Iversen, L. L. 198,208, 330,441,441 134,171 209, 2U, 212, 218, 225, 278, - see Archer, S. 506, 519 Aurbach, G. D., see Granner, 281,570,611,621,622,655, - see Lands, A. M. 286, 320, D. 369, 375,433, 448 813, 814, 816, 820, 821, 822, 321,324,325,329,333 - see Melson, G. L. 433, 454 828,830,831,834,839 - see Wylie, D. W. 273, 282, Austin, L., Livett, B. G., - see Kopin, I. J. 276, 281, 750, 761 Chubb, I. W. 194,219 906,928 Aronson, R. B., see Cotzias, G. - see Livett, B. G. 574, 602, - see Krakoff, L. R. 232, 266 C. 880, 885 613 - see La Brosse, E. H. 275, Arqueros, L., see Viveros, O. Avakian, O. V., Gillespie, J. S. 281,903,912,928 H.34, 44, 239, 246,250,254, 204,219,747,749,756 - see Landsberg, L. 195, 196, 257,261,269,540,542,551, Aviado, D. M., Sadavongvivad, 226 553,555,556,557,558,559, C.161,171 - see Marki, F. UO, U5, 560,562,565,587,595,598, Awapara, J., Perry, T. L., Han• 179 600,604,617 ly, C., Peck, E. 188, 219 - see Molinoff, P. 629, 656, Arstila, A. W., Hopsu, V. K. Axelrod, J. 2, 5, 6, 8, 11, UO, 814, 816, 822, 840, 879, 52,72 123,171, 189, 197,200,219, 892 Arunlakshana, 0., Schild, H. O. 231,232,261,262,270,272, - see Mueller, R. A. 194, 195, 291,330 279,504,505,519,619,620, 226,813,814,822,826,830, Arushanyan, E. B., Belozertser, 652, 857, 862, 881 834, 840, 904, 929 Yu. A. 516, 519 - Albers, R. W., Clemente, C. - see Noble, E. P. 466, 499, Asakawa, S., see Akabane, J. D. 272,279, 816, 835 533 587,605 - Gordon, E., Hertting, G., - see Potter, L. T. 189, 196, Asatoor, A. M., Chamberlain, Kopin, I. J., Potter, L. T. 217,227,239,267,468,533, M. J., Emmerson, B. T., 338,357 574, 614, 629, 630, 657, Johnson, J. R., Levi, A. J., - Hertting, G., Patrick, R. W. 658 Milne, M. D. 877, 881 519 - see Rosell, S. 208, 228 - Dalgliesh, C. E. 189, 219 -- Potter, L. 827, 836 - see Senoh, S. 857, 896 Ascher, P. 98, 105 - Kopin, I. J., Mann, J. D. - see Snyder, S. 271, 282, 822, Ashcroft, G. W., see Guldberg, 912,924 823,842,901,932 H. C. 859, 860, 888 - Laroche, M. J. 272, 273, - see Tamarkin, N. R. 860, - see Moir, A. T. B. 859, 872, 279,506,519,814,836 897 892 - Mueller, R. A., Thoenen, H. - see Thoa, N. B. 356, 361, Ashford, T.P., Porter, K. R. 195,219 622,659 372,442 - Senoh, S., Witkop, B. B. - see Thoenen, H. 194, 229, Ashmore, J. 319, 330 270,279 235, 268, 600, 616 - see Allen, D. O. 301, 302, - Shein, H. M., Wurtman, - see Udenfriend, S. 189, 229 330,387,441 R. J. 429, 430, 431, 442, - see Weil-Malherbe, H. 209, - see Bewsher, P. D. 374, 823,836 213, 230, 504, 537, 850, 899 443 - Tomchick, R. 6, 11,270,272, - see Weinshilboum, R. 855, - see Christian, D. R. 394, 279, 504, 519, 858, 881 899 395,444 - Weil-Malherbe, H., Tom• - see Whitby, L. G. 198, 211, - see Malaisse, W. J. 421, 422, chick, R. 197, 198,219,239, 230,239,269,276,282,816, 453 262,816,836 844 - see Mayhew, D. A. 419, 454 - Whitby, L. G., Hertting, G. - see Wolfe, D. E. 52,56, 78, - see Struck, E. 373, 374, 459 500,505,519 200,216,230,815,844 - see Williamson, J. R. 371, - Wurtman, R. J. 428, 431, - see Wurtman, R. J. 32, 45, 373,462 442 116,120,124,127,164,185, Askew, B. M. 500, 519 - see Daly, J. W. 857, 886 232,235,269,428,429,431, Assicot, M., see Bohuon, C. 917, - see Eisenfeld, A. J. 209, 222, 462,823,844,903,933 924 278,280,747,748,749,751, - see Zweig, M. 206, 230 Athos, W. J., McHugh, B. P., 757 Axelsson, J., Thesleff, S. 834, Fineberg, S. E., Hilton, J. - see Fischer, J. E. 278, 280, 836 G. 915, 924 816,837 Ayukawa, S., Hamada, M., Ko• Atuk, M. 0., see Mulholland, S. - see Glowinski, J. 50, 74, jiri, K., Takeuchi, T., Hara, G. 901, 929 193,198,208,210,212,213, T., Nagatsu, T., Umezawa, Aubock, L., see Ratzenhofer, 218,223,236,264,278,280, H.191,219 M.909, 911, 915,930 465,466,467,468,469,495, Azuma, T., Binia, A., Vischer, Auditore, G. V., Holland, W. 497,498,499,500,504,505, M. B. 114, 115, 140, 142, C.376,442 507,526,820,838 171 Author Index 937

Babad, H., Ben-Zvi, R., Bdolah, Ballinger, W. F., see Sunder• Barclay, M., see Skipski, V. P. A., Schramm, M. 424, 442 man, C. R. 912, 932 592,615 Bach, L. M. N., see Crammer, Balogh, K., Drask6czy, P. R., Barcroft, H., Peterson, E., J. I. 517, 523 Caulfield, J. B. 923, 924 Schwab, R. S. 494, 520 Bachmann, K., see Schmid, E. Balzer, H., Holtz, P. 742, 752, Barger, G., Dale, H. H. 284, 914,931 756 330,353,357,854,882 Bachmann, K. P. 917, 924 - Palm, D. 190, 220 Bargmann, W., von Hehn, G., Bachmann, L., see Salpeter, M. Banerjee, U., Feldberg, W., Lindner, E. 416, 442 M.77 Lotti, V. J. 510, 520 Barka, T. 425, 426, 442 Bachmann, R. 560, 605 Bangham, A. D., Horne, R. W. Barker, B., see Madison, L. L. Backstrom, T., see Goldstein, 593,605 422,453 M.873,888 Banister, R. J., Portig, P. J., Barkhoff, E. R., see Wiist, G. Bacq,Z.M.2,8,11,202,219 Vogt, M. 19,39, 115,171 913,933 - Fischer, P. 167,171 Banks, P. 244, 250, 255, 262, Barlett,.J. D., see Harrison, T. - Gosselin, L., Dresse, A., Ren- 539,541,546,548,549,550, S.915,927 son, J. 273, 280, 506, 519, 556,560,586,587,589,590, Barlow, C. F., see Roth, L. J. 814,836 591,600,605 534 - Lecomte, J. 114, 171 - Biggins, R., Bishop, R., Barnard, T. 416, 442 - Renson, J. 754, 756 Christian, B., Currie, N. - Lindberg, O. 416, 442 Bar, H. P., Hechter, O. 368, 589,606 - Skala, J., Lindberg, O. 411, 382, 384, 386, 442 - Helle, K. 5, 12, 34, 39, 68, 417,442 Baer, J. E., see Udenfriend, 72,555,556,557,605 - see Skala, J. 411, 416, 459 S.186,229,233,268 -- Mayor, D. 217, 220, 250, Barnes, C. D., see Herman, E. Bassler, R., Habighorst, L. V. 262,605 H. 517, 528 909,911, 924 - Kapeller, K., Mayor, D. 53, Bagchi, S. P., McGeer, P. L. 60,72 Barnet, A., see Coleman, M. P. - Magnall, D., Mayor, D. 602, 862,875,880,885 195,220 Barnett, A., Staub, M., Sym• BagnoIi, P., Brunelli, M., Mag• 606 chowicz, S. 339, 357 ni, F., Viola, M.l09 Banna, N. R., see Anderson, E. - Symchowicz, S., Taber, R. Baird, C. E., see Abe, K. 434, G. 517, 519 I. 212,220 441 Bapna, J. S., see Menon, M. K. - Taber, R. I. 486, 504, 520 - see Butcher, R. W. 314, 331, 502,531 Barolin, G. S., Bernheimer, H., 381, 382, 386, 444 Barajas, L., Latta, H. 52, 72 Hornykiewicz, O. 856, 882 Baird, T. J., Binnion, P. F. 398, Barany, E. H., Treister, G. 817, - Hornykiewicz, O. 860, 882 442 836 Barr, A. N., see Celesia, G. G. Bak, I. J. 61, 72 - see Sears, M. L. 817, 841 861,865,885 - see Grobecker, H. 587, 590, Barbeau, A. 846, 855, 860, 861, 862,866,869,870,881,882 Barrett, A. M. 442 610 Barrett, F. M., see Andersen, Bakay,L.464,474,519 - De Groot, J. A., Joly, J. G., Baker, R. G., Anderson, E. G. Raymond-Tremblay, D., S.0.85 518,519 Donaldson, J. 858, 882 Barrett, R. E., see Neff, N. H. - see Anderson, E. G. 517, 519 - Friesen, H. 862, 882 58,76,848,893 Baker, T. D., see Riddell, D. H. - GilIo-Joffroy, L., Boucher, - see Yahr, M. D. 861, 867, 901,930 R., Nowaczynski, W., Ge• 899 Baldesberger, R., see Tye, A. nest, J. 864, 882 Barrnett, R. J., see Bloom, F. 346, 351, 362 - Jasmin, G. 880, 882 E.17,40,53,56,58,60,61,72 Baldessarini, R. J., Kopin, I. J. - McDowell, F. H. 845, 882 - see Reik, L. 366, 368, 457 499, 519, 588, 605 - Murphy, G. F., Sourkes, T. - see Sabatini, D. D. 48, 77 - see GIowinski, J. 270, 280, L. 855, 882 - see Van Orden, L. S. 46, 48, 468,504,526 - Singh, P., Gaudreau, P., 53,56,58,60,78,815,843 - see Wurtman, R. J. 874, Joubert,M. 858, 882 - see Wood, J. G. 17,44,48, 899 - Sourkes, T. L., Murphy, G. 50,52,61, 78 Baldwin, B. A., Ingram, D. L., F.860, 869, 879,882 Barski, G., see La Brosse, E. H. Le Blanc, J. 171 - Trombitas, S. 855, 882 917,928 Baldwin, D. M., see McKinney, - see Montplaisir, J. 851, 892 Barsky, J., see Griesemer, E. C. T. D. 122,180 - see Pushpathadam, J. J. 271,280,752,758 Ball, E. G. 412, 442 858,894 - see Zeller, E. A. 7,15, 271, - see Frerichs, H. 388, 447 Barber, Coupland, R. E. 32 282 - see Hayward, J. S. 411, 417, Barbour, H. G., Wing, E. S. Barsoum, G. S., Gaddum, J. H. 449 482,520 111,172 - see Jungas, R. L. 381, 451 Barchas, J. D., Ciaranello, R. Bartholini, G., Burkard, W. P., - see Kornacker, M. S. 409, D., Steinman, A. M. 119, Pletscher, A., Bates, H. M. 411, 412, 451 172 496,497,520 - see Markus, H. B. 385, 453 - Freedman, D. 119, 172 - Da Prada, M., Pletscher, A. Ballard, K., Rosell, S. 387, 442 - see Lovenberg, W. 814, 840 496,520,879,882 938 Author Index

Bartholini, G., Gey, K. F., Plet• Baxter, J. H., jr., see Greer, C. Belleau, B., Fang, M., Burba, Bcher, A. 235,262,851,876, M.2,14 J., Moran, J. 7, 12 882 Bayer, G., Wense, T. 85, 105 Belocopitow, E., Appleman, M. - Kuruma, I., Pletscher, A. Bayliss, O. B., see Adams, C. M., Torres, H. N. 403, 442 877,882 W. M. 48, 72 - Fernandez, M. C. C., Bim• - Pletscher, A. 496, 520, 853, Baylor, D. A., see Nicholls, J. baumer, L., Torres, H. N. 863, 868, 875, 876, 882 G. 686, 722 403,442 -- Kuruma, I. 877, 882 Bayo, J. B., see Jalon, P. G. De - see Torres, H. N. 404, 460 - see Kuruma, I. 876, 891 111,178 Belozertser, Yu, A., see Arus• - see Pletscher, A. 873, 876, Bdolah, A., Ben-Zvi, R., hanyan, E. B. 516, 519 893 Schramm, M. 424, 442 Belpaire, F., Laduron, P. 540, - see Tissot, R. 897 - Schramm, M. 424, 442 557,559,606 Bartholomew, J. R., see Hin• - see Babad, H. 424, 442 - see Laduron, P. 31, 42, 233, tersberger, H. 905, 918, 920, - see Schramm, M. 425, 458 239,240,243,246,254,266, 921,927 Beani, L., Bianchi, C., Crema, 539,542,572,576,578,600, Barton, A. A., Causey, G. 689, A. 792, 803 602,612 715 Beattie, J. 0., see Prescott, L. Beltran, G., Leiderman, E., Bartonicek, V., Dahlstrom, A., F. 620, 658 Stuckey, W. J., Ferrans, V. Fuxe, K. 499, 520 Beaufay, H., Jaques, P., Baud• J., Mogabgab, W. J. 924 Bartsch, G. E., see Katz, J. huin, P., Sellinger, O. Z., Ben-Zvi, R., see Babad, H. 424, 389,451 Berthet, J., de Duve, C. 442 Baserga, R. 425, 426, 442 249,262 - see Bdolah, A. 424, 442 - Heffler, S. 425, 426, 442 Beaulnes, A., see Cordeau, J. P. Bender, D. A., see Coulson, W. - see Kirby, K. C., jr. 426, 476,523 F. 853, 885 451 Beauvallet, M., Fugazza, J., Benedeczky, 1.560,601,606 - see Malamud, D. 425, 426, Solier, M. 118, 172 - Lapis, K. 25, 39, 909, 911, 453 Beaven, M. A., see Maickel, R. 924 - see Martin, A. P. 426, 453 P. 349,360 - Puppi, A., Tigyi, A., Lissak, - see Sasaki, T. 425, 426, 458 - see Montanari, R. 196,226 K. 596, 606 - see Whitlock, J. P., jr. 425, Beck, H., see Boudin, G. 867, Benfey, B. G., Varma, D. R. 426,461 884 298,330,353,357 Bass, A. 470, 483, 520 Beck, J. L., see Buhs, R. P. - see Hokin, M. R. 594, 611 Bass, A. D., see Chambers, J. 620,652 - see Millar, R. A. 132, 180 W.372,444 Becke, H., see Philippu, A. 500, - see Varma, D. R. 338, 362, Bass, H., see Fleckenstein, A. 533 651,660 336,337,343,358,737,757, Becker, F. F., Bitensky, M. W. Benigni, J., see Daly, J. W. 833,837 369,442 857,886 Bass, P., see Weisbrodt, N. W. Becsei, I., see DeSchryver, C. Benington, F., see Smythies, J. 327,335 159,170,182 R. 866, 897 Bastide, F., Jard, S. 434, 442 Bedard, P., Larochelle, L., Pa• Benitz, H., see Crain, S. M. 819, Bates, H. M., see Bartholini, rent, A., Poirier, L. J. 847, 837 G. 496, 497, 520 882 Benkert, O. 476, 520 Battaglia, G. 23, 39 -- Poirier, L. J., Sourkes, - see Matussek, N. 862, 892 - see Muratori, G. 23, 43 T. L. 851, 882 Benko, A., see Faredin, I. 130, Battenberg, see Bloom, F. E. 67 - see Lancaster, G. 847, 868, 169,176 Battista, A. F., Goldstein, M., 891 Benmiloud, M. 166, 167,172 Nakatani, S., Anagnoste, B. Beetham, K. L., see Thomson, - Euler, U. S. v. 815, 816, 836 847,882 J.F.460 Bennet, M. R., Rogers, D. C. - see Goldstein, M. 847, 850, Behringer, K., Wilmanns, K. 731,756 863,874,880,887,888 868,882 Bennett 878 Baudhuin, P., see Beaufay, H. Bein, H. J. 5, 12 Bennett, A. 298, 330 249,262 Belehradek, J., see LaBrosse, Bennett, L. L., see Curry, D. L. Baumgarten, H. G. 114, 172 E. H. 917, 928 421,445 - Braak, H. 114, 172 Belford, J., Cunningham, M. A. - see Grodsky, G. M. 420,421, -- Wartenberg, H. 68, 72 393,442 448 - Falck, B., Holstein, A.-F., Bell, C. 117,172,754, 756 Bennett, M. R., Merrillees, N. Owman, Ch., Owman, T. - Vogt, M. 567, 568, 569, C. R. 665, 715 126,163,172 606 Bensch, K. G., see Sabatini, D. - Holstein, A.-F. 144, 172 Bell, M. 919, 920, 921, 924 D. 48,77 -- Owman, Ch. 796, 803 Bellas, J. E. 900, 924 - see Staley, N. A. 919, 920, - see Wartenberg, H. 52, 68, Belleau, B. 10, 12, 216, 220 932 78 - Burba, J. 273, 280, 506, - see Van Orden, L. S. 46, 52, Baust, W., Niemcyzyk, H., 520, 814, 836 53, 56, 58, 60, 78, 348, 362, Vieth, J. 477, 520 -- Pindell, M., Reiffenstein, 570,571,616,634,660,729, Baxter, B. L. 489, 520 J.7,12 734,761,814,817,833,843 Author Index 939

Bensinger, R., see Handler, J. Bertler,A., Falck, B., Von Meck• Bhagat, B., see Friedman, A. H. S.433,434,449 lenburg, C. 114,136,172 142, 160, 176 Bentley, G. A. 765, 803 -- Owman, Ch., Rosengren, - see Musacchio, J. M. 337, Berdal, P., Braaten, M., Cap• E.133,172,872,883 360,635,656 pelen, C., Mylius, E. A. 923, -- Rosengren, E. 465, 496, Bhattacharya, I. C. 199, 202, 924 520 203,209,212,220 ---- Walaas, O. 922, - Hall, G., Hillarp, N.-A., Bhoola, K. D., Calle, J. D., 923,924 Rosengren, E. 241, 242, 262 Schachter, M. 99, 105 Berg, G. R., see Klein, D. C. - Hillarp, N.-A., Rosengren, Bianchi, C. P. 392, 396, 443 429,430,451 E. 123,172, 236, 237, 241, - see Beani, L. 792, 803 Bergeret, B., Blaschko, H., Ho• 262 - see Woodward, J. K. 665, wes, R. 7, 12 - Rosengren, A. M., Rosen• 666,675,725 Bergmann, S., see Godwin• gren, E. 241, 262 Bianchi, S. 89, 105 Austen, R. B. 870, 887 - Rosengren, E. 4, 12, 118, Bianchine, J. R., see Morgan, Berk, L., see Zaimis, E. 198, 148,149,150,152,153,172, J.P. 862,871, 874,876,892 230, 821, 830, 844 188,220,495,496,520 - see Peaston, M. J. T. 871, Berkowitz, G. M., see Merrill, - see Carlsson, A. 5, 13, 244, 874,876,893 S.915,929 263,336,358,814,836 - see Rivera-Calimlim, L. 871, Berlind, A., Cooke, I. M., Gold• Bertrand, C., see Papeschi, R. 894 stone, M. W. 100, 105 859,893 Bickel, M. H., see Sulser, F. Berman, E. R., see Zeller, E. A. Besse, J., Furchgott, R. F. 289, 499,500,536 7,15 292, 293, 297, 330 Bickerton, R. K. 313, 314, 327, Bernard, E., see Torres, H. N. Besser, M. I. B., Pfau, A. 902, 330,745,756 404,460 924 Bieck, P., Stock, K., Wester- Bernard, P., see DeSchaepdry• Bessirard, D., see Halpern, B. mann, E. 170, 172 ver, A. F. 132, 161, 166, N. 496, 527 Biedl, A. 89, 105 182 Bessis, M., see Manger, W. M. - Wiesel, J. 123, 172 Berneis, K. H., Pletscher, A., 871,891 Biel, J. H., Lum, B. K. B. 814, Da Pl'ada, M. 250, 252, 262, Best, J. B., Noel, J. 54, 60, 72 836 544,558,594,606 Bethea, M. D., see Gourley, D. Biersteker, P. A., see Cate, J. Bernhard, C. G., Skoglund, C. R. H. 383, 448 ten 515, 522 R. 515, 520 Bettag, W., Holbach, K. H. Biggins, R., see Banks, P. 589, Bernheimer, H. 121, 157, 172, 862,883 606 856,882 Bettex, M., see Donath, A. 901, Billingsley, P. R., Ranson, S. - Birkmayer, W., Hornykie• 905,912,913,925 W.688,715 wicz, O. 856, 859, 868, 879, Bevan, J. A., Chesher, G. B., - see Ranson, S. W. 690, 723 882,883 Su, C. 567, 568, 569, 570, Bindler, E., see Gyermek, L. --- Jellinger, K., Seitel• 606 705, 708, 709, 718 berger, F. 848, 856, 883 - Nedergaard, O. A. 569, 606 Bing, R. J., see Wegmann, A. - Hornykiewicz, O. 854, 856, - Osher, J. V. 325, 330 125,185,815,843 858,883 - Su, C. 767,803 Binia, A., see Azuma, T. 114, - see Barolin, G. S. 856, 882 - Verity, M. A., 569, 606, 731, 115,140,142,171 Bert, J. K., see Moore, K. E. 756 Binnion, P. F., see Baird, T. J. 502,532 - see Nedergaard, O. A. 773, 398,442 Bertaccini, G. 95, 96, 105 810 Birkhauser, H. 465, 474, 520 Bertani, L. M., see Gitlow, S. E. - see Su, C. 356, 361 Birkmayer, W. 851, 857, 863, 845,887 - see Verity, M. A. 569, 616, 883 Berthet, J., see Beaufay, H. 730,731,761 - Hornykiewicz, O. 4, 12, 188, 249,262 Beviz, A., Lundholm, L., Moh• 220, 846, 860, 861, 868, 870, - see Pryor, J. 373, 375, 456 me-Lundholm, E. 409, 443 879,880,883 Berti, F., Shore, P. A. 500, 520, Bewsher, P. D., Ashmore, J. - see Bernheimer, H. 848, 622,623,652 374,443 856, 859, 868, 879, 882, 883 Bertler, A. 155, 172, 497, 505, Beyer, K. R., Shapiro, S. R. Birks, R., MacIntosh, F. C. 765, 520 270,280 788,803 - Carlsson, A., Lindqvist, M., Bhadrakom, S., see Furchgott, Birmingham, A. T. 730, 756, Magnusson, T. 498, 520 R. F. 295, 296, 332 815,836 -- Rosengren, E. 112, 118, Bhagat, B. 217, 220, 772, 803, - Wilson, A. B. 356, 357, 763, 172,498,520 816,836 773,774,803 - Falck, B., Gottfries, C. G., - Bovell, G., Robinson, I. M. Birnbaumer, L., Pohl, S. L., Ljunggren, L., Rosengren, 737,756,772,803 Rodbell, M. 382, 384, 443 E.147,172 - Ragland, R. 647, 652 - Rodbell, M. 381, 382, 384, -- Hillarp, N.-A., Rosen• - Robinson, I. M., West, W. 386,443 gren, E., Torp, A. 125, 128, L.803 - see Appleman, M. M. 401, 131,160, 161, 165, 166, 167, - Shideman, F. E. 354, 355, 404,441 170,172 357 - see Belocopitow, E. 403, 442 940 Author Index

Birnbaumer, L., see Pohl, S. L. Blakeley, A. G. H., Brown, G. Bleckman, 1., Jurna, 1., Rum• 368,456 L., Ferry, C. B. 211, 213, mel, W. 796, 803 - see Rodbell, M. 382, 384, 220,569,576,606,764,767, Blessing, J. A., see Stone, C. A. 385,457 803 468, 536, 646, 659 Birrell, .J. H. W., see Hoffman, - Dearnaley, D. P. Harrison, Bligh, J. 484, 520 H. 23, 24, 42 V. 568, 606 - Cottle, W. H. 483, 484, 486, Birzis, L., Carregal, E. J. A. Blanco, M., see Bitensky, M. 487,488,492,520 687,715 W.368,369,443 -- MasJney, M. 487, 520 - see Hemingway, A. 494, 528 Blank, W., see Luse, S. A. 865, - Maskrey, M. 487, 520 Bisby, M. A., Fillenz, M. 588, 891 Blinks, J. R. 295, 306, 307, 310, 603,606 Blaschko,H.2,3,4,6,7, 10, 12, 314, 323, 330, 745, 746, 756 Biscardi, A. M., see Chiocchio, 186,188,189,211,212,220, Bliss, E. L., see Zapata, P. 52, S. R. 23, 40, 169, 174, 188, 232,237,240,262,484,520, 70,78 221,922,925 619,652, 845, 848, 852, 853, Blizzard, R. M., see Parra, A. - see Segura, E. T. 115, 139, 854,883,904,924 435,455 183 - Born, G. V. R., D'Iorio, A., Bloodwell, R. D., see Cooper, T. Bischoff, F., Torres, A. 855, Eade, N. R. 249, 250, 252, 815,837 883 262,539,606 Bloom, F. E. 46, 47, 48, 49, 50, Biscoe, T. J., Lall, A., Samp- - Buffoni, F., Weissman, N., 54, 56, 63, 64, 68, 72, 543, son, S. R. 23, 24, 39 Carnes, W. H., Coulson, W. 920 - Purves, M. J. 24, 39 F. 8, 12 - Aghajanian, G. K. 46, 50, - Sampson, S. R. 23, 40 - Burn, J. H., Langemann, H. 61, 63, 64, 71, 72 -- Purves, M. J. 23, 40 188, 220, 619, 652, 852, 883 - Aigeri, S., Groppetti, A., - Stehbens, W. E. 23, 40 - Chrusciel, T. L. 5, 12, 188, Revuelta, A., Costa, E. 47, - see Sampson, S. R. 24, 44 220,465,496,498,505,520, 64,67,72 Biserte, G. 906, 924 878,883 - Barrnett, R. J. 17,40,53, Bishop, G. H., Heinbecker, P. - Comline, R. S., Schneider, 56, 58, 60, 61, 72 688,690, 715 F. H., Silver, M., Smith, A. - Crayton, J. W. 67, 72 - see Heinbecker, P. 690, 719 D.5, 12, 68, 72, 250, 257, - Giarman, N. J. 46, 52, 56, Bishop, J. S., Larner, J. 370, 262, 540, 555, 557, 576, 606 58, 60, 72, 319, 330 443 - Firemark, H., Smith, A. D., - Groppetti, A., Revuelta, A., - see Larner, J. 404, 452 Winkler, H. 26, 40, 251, 257, Costa, E. 828, 836 Bishop, R., see Banks, P. 589, 262,592,593,606 - Iversen, L. L., Schmitt, F. 606 - Hagen, J. M., Hagen, P. 5, 0.5,12 Bitensky, M. W., Russell, V., 12, 249, 262, 539, 574, 606, - Kurpys, Battenberg 67 Blanco, M. 368, 369, 443 906,924 - see Aghajanian, G. K. 61, -- Robertson, W. 368, 443 - Hagen, P., Welch, A. D. 26, 63, 72 - see Becker, F. F. 369, 442 31, 40, 232, 248, 255, 262 - see Cohen, K. L. 419, 445 - Helle, K. B. 250, 262 - see Boadle, M. C. 47, 72 Bjorklund, A. Cegrell, L. 866, - Hope, D. B. 96, 102, 105 - see Crayton 54 - see Groppetti, A. 857, 888 883 - Holton, P., Stanley, G. H. -- Falck, B., Ritzen, M., S.188,220,878,883 - see Hughes, J. 203, 225 - see Roth, R. H. 50, 53, 71, Rosengren, E. 787, 803 - Jerrome, D. W., Robb• - Falck, B., Rosengren, E. Smith, A. H. T., Smith, A. 77 153,172 D., Winkler, H. 593, 601, - see Shorr, S. S. 52, 70, 77 Blaber, L. C., Bowman, W. C. 606,906,907,908,909,911, - see Siggins, G. R. 53, 54, 56, 800,803 924 58,60,77 - Gallagher, J. P. 800, 803 - Levine, W. G. 8, 12 - see Stjarne, L. 53, 68, 77, - see Christ, D. D. 800, 805 - Richter, D., Schlossmann, 198, 201, 229, 240, 268 - see Gallagher, J. P. 802, 806 H. 5, 12, 271, 280, 620, 652 - see Van Orden, L. S. 46, 48, Black, 1. B. 375, 443 - Smith, A. D. 5, 12 53,56,58,60,78,815,843 Blackard, W. G., Heidingsfel- -- Winkler, H. 26, 40, 250, Bloom, G., see Ostlund, E. 134, der, S. A. 435, 443 262 181 Blackman, J. G., Crowcroft, P. - Welch, A. D. 5, 12, 25, 40, -- Euler, U.S. v. 18, 40 J., Devine, C. E., Holman, 50, 72, 248, 262, 538, 606 --- Lishajko, F., Ritzen, M. E., Y onemura, K. 664, - see Bergeret, B. 7, 12 M., Adams-Ray, J. 18, 40, 668,674,677,688, 715 - see Buffoni, F. 8, 12 113, 134, 172 - Ginsborg, B. L., Ray, C. - see Demis, D. J. 4, 13 -- Fange, R. 18, 40 664,666,669,670,671,672, - see Pratesi, P. 352, 361 Blukoo-Allotey, J. A., Vincent, 673, 674, 675, 677, 695, 715 - see Prusoff, W. H. 249, 267 N. H., Ellis, S. 399, 443 - Holman, M. E. 664, 715 Blaufox, M. D., see Fotino, S. Blum, J., see Burkard, W. P. - Purves, R. D. 664, 668, 672, 864,887 828,829,836 674,675,677,715 Blecher, M., Merlino, N. S., Blum, J. J. 85, 105 Blackwell, B., Marley, E. 508, Ro'ane, J. T. 382, 443 - Kirshner, N., Utley, J. 85, 520 --- Flynn, P. D. 390, 443 106 Author Index 941

Boadle, M. C., Bloom, F. E. 47, Bonham Carter, S., Karoum, Boucher, R., see Barbeau, A. 72 F., Sandler, M., Youdim, 864,882 - Hughes,J.,Roth,R. H.195, M. B. H. 850, 883 - see Genest, J. 130, 169, 176 220 - see Youdim, M. B. H. 850, - see Poirier, L. J. 154, 181, - see Govier, W. C. 592, 610 899 847, 853, 868, 893 Boakes, A. J., see Hunter, K. Bonin, Himms-Hagen, J. 418 Bouckaert, J., see Nagasaka, R. 863, 869, 889 Bonomi, L., see Bogdanski, D. M.298,333 Bocklage Bourne, B., see Bou• F. 165,172 Boudin, G., Castaigne, P., Lher• cek, R. J. 117,173 - see Brodie, B. B. 136,137, mitte, F., Beck, H., Guil• Boehlke, K. W., Tiemeier, O. 139,140,142,147,173 lard, A., Marteau, R., Pe• W., Eleftheriou, B. E. 114, Bonvallet, M., Dell, P., Hiebel, pin, B., Roudot, P., Raphy, 136,172 G. 477, 521 B. 867, 884 Boeles, J. T. F., see Cate, J. Booker, B., see Levi-Montalci• Boukma, S. J., see Johnson, G. ten 515, 522 ni, R. 814, 819, 820, 831, A. 503, 504, 528 Bonisch, H., see Graefe, K. H. 840 Boulding, J. E., see McGeer, P. 740,741,742,758 Bookstein, J. J., see Harrison, L.860, 861, 867, 868, 869, Boero, G. C., see Gessa, G. L. T.S.912,927 874,891 881,887 Booth, A. N., Williams, R. T. BouIlin, D. J. 588, 606, 618, Boff, E., Heise, G. A. 496, 521 877,884 652, 781, 803 - see Scheckel, C. L. 496, 498, - see DeEds, F. 877, 878, 886 - O'Brien, R. A. 873, 879, 535,863,880,895 - see Masri, M. S. 857, 892 884 Bogaert, M. G., see Langer, S. Booth, D. A. 467, 488, 490, 501, Boulton, A. A., Pollitt, R. J., Z. 754, 759 510, 512, 521 Majer, J. R. 850, 851, 884 Bogdanski, D. F., Bonomi, L., Borchard, F., Vogt, M. 159, 172 - Quan, L., Majer, J. R. 851, Brodie, B. B. 165, 172 Borcherding,J. W., see Everett, 884 - Brodie, B. B. 204, 220 G. N. 853, 875, 879, 886 Boura, A. L. A., Copp, F. C., - Weissbach, H., Udenfriend, Borchgrevink, C. F., see Havel, Duncombe, W. G., Green, S.504,521 R. J. 404, 449 A. F., McConbrey, A. 776, - see Brodie, B. B. 136, 137, Boretti, G., see Erspamer, V. 803 139, 140, 142, 147,173 189,222 - Green, A. F. 776, 803, 814, - see Kuntzman, R. 150, 179 Borg, D. C., see Van Woert, M. 836 - see Mitoma, C. 878, 892 H. 857, 898 Bourgoignie, J., Guggenheim, - see Tissari, A. H. 213, 229 Borison, H. L. 471, 521 S., Kipnis, D. M., Klahr, S. Bohr, D. F. 323, 325, 330 - see McCarthy, L. E. 466, 443 Bohuon,C.905,924 530 Bouvier, G., see Poirier, L. J. - Guerinot, F. 902, 913, 917, Born, G. V. R. 209, 220 154,181 918,924 - Hornykiewicz, 0., Stafford, Bovell, G., see Bhagat, B. 737, - La Brosse, E. H., Assicot, A. 132,172 756,772,803 M., Amar-Costesec, A. 917, - see BIaschko, H. 249, 250, Bowers, M. B., jr., Heninger, 924 252,262,539,606 G. R., Gerbode, F. 846, 860, - see Amar-Costesec, A. 904, Borowitz, J. L. 591, 606 862,884 917,924 - Fuwa, K., Weiner, N. 251, - see Van Woert, M. H. 859, - see La Brosse, E. H. 917, 262 862,865,866,872,876,879, 919,928 Borowskaja, A. J., see Law• 898 Boissier, J. R., Simon, P. 496, rentjew, B. 1. 814, 830, 839 Bowles, G. R., see Weil-Mal- 505,521 Borud, 0., see Gjessing, L. R. herbe, H. 495, 505, 537 Bokri, E., see Feher, O. 705, 921,926 Bowman, R. H. 433, 443 718 - see O'Gorman, L. P. 866, Bowman, W. C. 800, 803 Bollman, J. L., see Manger, W. 874, 876, 893 - CaIlingham, B. A., Cuth• M.120,180 Borzecki, Z., see Nybiick, H. bert, A. W. 766, 796, 803 Bonaccorsi, A., Jespersen, J., 467,468,499,533 -- Osuide, G. 515, 521 Garattini, S. 732, 756 Boshart, C. R., Will, L., Pirre, - Goldberg, A. A. J., Raper, Bondareff, W.52,56,58,60, 72 A., Ringler, 1. 423, 443 C.796, 797, 798, 804 - Gordon, B. 52, 58, 73 Boshell, B. R., see Duke, W. - Hall, M. T. 297, 298, 330, Bone, A. D., see Weil-Malherbe, W.922,923,925 792,795,804 H. 4, 15, 132, 185 Boska, D., see Machova, J. 695, - Nott, M. W. 319, 330, 796, Boner, A., see Langemann, H. 697, 701, 708, 709, 710, 722 797, 798, 800, 802, 804 853,891, 902, 928 Bossaert, H., see Amery, A. - Raper, C. 401, 402, 443, 796, Bongiovanni, A. M., see Young, 627,652,916,924 797, 798, 799, 800, 804 R. B. 920, 921, 933 Botos, A., see Faredin, 1. 130, - Zaimis, E. 479, 521, 796, Bonham Carter, S., Hunter, 169,176 797,798,804 K. R., Laurence, D. R., Botturi, M., see Clementi, F. - see BIaber, L. C. 800, 803 Sandler, M., Stern, G. M., 52, 58, 60, 73, 778, 805 - see Raper, C. 800, 811 Youdim, M. B. H. 851, Boucek, R. J., Bocklage Bour• Boyarsky, S., Kirshner, N., 883 ne, B. 117,173 Labay, P. 170, 173 942 Author Index

Boyd, H., see Brandon, K. W. Breese, G. R., see Schildkraut, Brodie, B. B., see Nash, C. W. 767,804 J. J. 500, 535 278,281 Boyd, J. D. 24, 40 Breggin, P. R. 471, 521 - see Paoletti, R. 170,181 - see Lever, J. D. 23, 43 Brendel, K., see Bressler, R. - see Pletscher, A. 5, 15 Boyle, A. J., see McCann, D. S. 421,423,443 - see Shore, P. A. 272, 281 876,891 Brennan, J., see Caine, D. B. - see Smith, R. L. 170, 183 Bozorgmehri, P., seeFurchgott, 863,884 - see Spector, S. 272, 282, 505, R. F. 271, 280,742,752,757 Bresnick, E., see Mayfield, E. 536 Bozzi, R., Bruno, A., Allegran• D., jr. 425, 426, 454 - see Stern, D. N. 814, 842 za, A. 855, 884 Bressler, R., Cordon, M. V., - see Sulser, F. 499, 500, 536 - see Allegranza, A. 236, 261 Brendel, K. 421, 423, 443 - see Tagliamonte, A. 866, Braak, H., see Baumgarten, H. - see Entman, M. L. 398, 446 897 G. 68, 72, 114,172 Bricolo, A., Daile Ore, G. 862, - see Tissari, A. H. 213, 229 Braaten, M., see Berdal, P. 922, 884 - see Udenfriend, S. 189, 229 923,924 Bridgers, W., see Kopin, 1. J. Brodie, H. K. H., see Goodwin, Bradbury, S., Smith, A. D., 349,359 F. K. 846, 859, 862, 865, Winkler, H. 68, 73 Bridgman, C. S., see Jasper, H. 871, 872, 874, 875, 888 Bradham, L. S., Holt, D. A., H. 476, 528 Brody, H., see Pakkenberg, H. Sims, M. 382, 427,443 Briggs, F. N., see Hess, M. L. 846,857,893 Bradley, P. B. 476, 477, 521 398,449 Brody, J.

Brown, G. L., Dearnaley, D. P., Bruno, A., Bruno, S. C. 861, Burcin, A., see Porter, C. C. Geffen, L. B. 128, 129, 173, 884 497, 533, 644, 657, 823, 841 604,606 - see Allegranza, A. 236, 261 Burford, H., Leick, J., Walas• - Gillespie, J. S. 211, 220, 240, - see Bozzi, R. 855, 884 zek, E. J. 743, 756 262, 271, 280, 753, 756 Bruno, S. C., see Bruno, A. 861, Burford, R., see Bradley, P. B. - Goffart, M., Vianna Dias, 884 477 M.796, 797, 798, 799, 800, Buckley, G., Consolo, S., Gia• Burgen, A. S. V., Dickens, F., 804 cobini, E., Sioqvist, F. 662, Zatman, L. J. 766, 804 - Holmes, O. 686,691, 694, 716 716 - Iversen, L. L. 207, 220, 649, - Pascoe, J. E. 688, 689, 690, Buckley, G. A., Jordan, C. C. 652 716 299,330 Burger, A., Philippu, A., Schu• - see Blakeley, A. G. H. 211, Buckner, C. K., Patil, P. N. 323, mann, J. H. 205, 220 213,220,569,576,606,764, 331 - see Philippu, A. 500, 533, 767,803 Budd, G. C., Salpeter, J\L M. 588,614 - see Goffart, M. 800, 807 52, 56, 58, 60, 73 Burger, M., Langeman, N. H. Brown, H. A., see Fuller, A. M. Budge, J. L. 832, 836 904, 905, 906, 925 923,926 Bueding, E., BUibring, E. 798, Burghardt, C., see Sheppard, Brown, H. D., Chattopadhyay, 804 H. 433, 459 S. K., Matthews, W. S. 392, - Butcher, R. W., Hawkins, Burkard, W. P., Gey, K. F., 443 J., Timms, A. R., Suther• Pletscher, A. 814, 836, 862, -- Spiut, H. J., Spratt, J. land, E. W., jr. 405, 406, 884 S., iI., Pennington, S. N. 444 - Jalfre, M., Blum, J. 828, 433,443 - Kent, N., Fisher, J. 405, 829,836 Brown, J. D., Stone, D. B. 385, 406,444 - see Bartholini, G. 496, 497, 444 Bueker, E. D. 818, 836 520 Brown, M. L., see Korol, B. 648, - see Schenken, 1. 819, 841 - see Gey, K. F. 853, 867, 887 655 BUibring, E. 2, 12, 231, 263, - see Pletscher ,A. 504,506,533 Brown, N. B., see Larner, J. 783,784,804 - see Schwartz, D. E. 499, 535 404,452 - Burn, J. H. 336, 357, 515, Burke, J. P., see Van Orden, L. Brown, S. R., see Foster, M. 516, 521, 762, 783, 800, 804 S.52,56,60,67,70,78,786, 131,176 -- Skoglund, C. R. 516, 521 787,812 Brown, T. G., see Lands, A. M. - Tomita, T. 298, 331, 795, Burkhalter, A., see Crawford, 286,320,321,324,325,329, 804 J. A. 853, 886 333 - see Brown, G. L. 798, 800, Burn, J. H. 197,202,220,271, Brown, Th. G., ir., see Arnold, 804 280,336,357,763,764,765, A. 320, 321, 330 - see Bueding, E. 798, 804 766,774,800,804,813,832, Brown, W. T., see Sourkes, T. Buffoni, F., Blaschko, H. 8, 12 836, 864, 884 L. 874, 897 - see Blaschko, H. 8, 12 - Froede, H. 767, 804 Brown-Grant, K. 425, 444 Buhs, R. P., Beck, J. L., Speth, - Gibbons, W. R. 588, 607, Browning, E. T., see William• O. C., Smith, J. L., Tren• 767, 774, 778, 781, 782, 804 son,J. R. 371, 373,374,462 ner, N. R., Cannon, P. J., - Langemann, H., Parker, R. Brownstein, M. J., Heller, A. Laragh, J. H. 620, 652 H. O. 122, 158, 173 432,444 - see Prescott, L. F. 620, 658 - Malik, K. U. 767, 804 - see Brown, D. A. 697, 716 Bullock, T. H., Horridge, G. A. - Philpot, F. J., Trendelen- Bruck, H., Gerstenbrand, F., 86,87,105 burg, U. 271, 280, 813, 816, Grundig, E., Teuflmayr, R. Bunnell, B. N., see Moyer, K. 836 850,884 E. 479, 532 - Rand, M. J. 5, 9, 12, 197, Bruck, K., see Wunnenberg, W. Bunney, W. E., ir., see Good• 210,220,277,280,336,337, 418,462 win, F. K. 846, 859, 862, 340,357,512,521,584,607, Brucke, F. T. v. 764, 804 865, 871, 872, 874, 875,888 762, 763, 764, 782, 804 Bruel, van den, 'V., Cession• Buonocore, E., see Meaney, T. -- Wien, R. 766, 805 Fossion, A., Vandermeulen, F. 913, 929 - Robinson, J. 271, 280, 816, R., Lecomte, J. 128, 159, Burack, W. R., Drask6czy, P. 836 167,173 R. 467, 468, 521 - Tainter, M. L. 336, 357 Bruinvels, J. 481, 501, 521 -- Weiner, N. 548, 550, - Weetman, D. F. 763,805 Brundin, T. 21, 40, 124, 173, 553,606 - Welsh, F. 781, 805 232,263 - Weiner, N., Hagen, P. B. - see Blaschko, H. 188, 220, - Hamberger, B., Norberg, 249, 261, 263, 548, 550, 607 619, 652, 852, 883 K.-A. 124,173 - see Weiner, N. 241, 269, 337, - see Breckenridge, B. MeL. Brunelli, M., see Bagnoli, P.109 338,362, 548, 550, 560, 617, 401,402,443 Brunfelter, B., see Ross, S. B. 914,933 - see Bulbring, E. 336, 357, 212,228,351,361 Burba, J., see Belleau, B. 7, 12, 515,516,521,762,783,800, Brunner, H., Hedwall, P. R., 273, 280, 506, 520, 814, 836 804 Maitre, L., Meier, M. 637, Burch, G. E., Phillips, J. H. 24, - see Fleckenstein, A. 336, 646,647,648,652 40 337,358,737,757 Author Index

Burns, B. D., see Brown, G. L. Butcher, S. G., see Anden, N. Callingham, B. A., see Zaimis, 798,800,804 E. 854, 878, 881 E.198,230,821,830,844 Burns, J. J., Salvador, R. A., - see Butcher, L. L. 853, 854, Callison, D., see Shah, N. S. Lemberger, L. 286, 331 866,884 852,896 - see Salvador, R. A. 286, 334 - see Udenfriend, S. 854, 898 CaIne, D. B. 845, 884 Burns, T. W., Langley, P. 381, Butterworth, K. R., Mann, M. - Brennan, J., Spiers, A. S. 386,444 30,40,122,173,233,263 D., Stern, G. M. 863, 884 Burnstock, G. 115, 139, 173, Buzzo, H. J., see Lands, A. M. - Karoum, F., Ruthven, C.R. 566,569,607,762,805 286,320,321,323,324,325, J., Sandler, M. 855, 859, - Holman, M. E. 763, 805 333 874,875,876,877,884 -- Kmiyama, H. 693, 716 Byer, S. S., see Porter, C. C. - Sandler, M. 850, 866, 867, - see Gannon, B. 136, 176 862,894 874,884 - see McLean, J. R. 115, 116, Bygdeman, S., von Euler, U. S. - Spiers, A. S. D., Stern, G. 142,180 190,192,220,233,234,263 M., Laurence, D. R., Armi• - see Men'illees, N. C. R. 729, -- Hokfelt, B. 233, 234, 263 tage, P. 861, 865, 873, 884 731,760 - Johnsen, 0. 209, 220 - Stern, G. M., Laurence, D. - see Read, J. B. 116, 128, 182 - see Stjarne, L. 568, 569, 616 R., Sharkey, J., Armitage, - see Robinson 54 Bygrave, F. L. 372, 376, 377, P.884 Burri, P. H., see Kaser, H. 919, 398,444 - see Sandler, M. 851, 874, 928 Byrt, P. 424, 444 878,895 Burrill, D. Y., see Ivy, A. C. Calver, D. M., see Parkes, J. D. 471,528 Cabana, B. E., Prokesch, J. C., 869,893 BUIsztyn, P., see FUIChgott, R. Christiansen, G. S. 906, 925 Calvert, D. N., Lech, J. J. 385, F. 289, 292, 332 Caboni, F., see Gessa, G. L. 881, 444 Burton, S. D., Mondon, C. E., 887 - see Brooker, W. D. 316, 323, Ishida, T. 376, 444 Cabrera, R., Cohen, A., Middle• 330 Buschiazzo, H., Exton, J. H., ton, S., Utano, L., Viveros, Camba, R., see Gessa, G. L. 887 Park, C. R. 370, 393, 444 H. 764, 805 Cameron, D. C., Warner, H. A., Buse, J., see Buse, M. G. 423, - Tonance, R. W., Viveros, Szabo, A. J. 918, 925 444 H.704,716,774,805 Cameron, I. L., Smith, R. E. Buse, M. G., Johnson, A. H., Cadkin, L., see Rosenthal, I. M. 408,416,444 Kupenninc, D., Buse, J. 903, 905, 909, 930 Cammarata, P. S., Cohen, P. P. 423,444 Caesar, P. M., see Sandler, M. 867,884 - see Kansal, P. C. 422, 451 855,895 Campbell, D., see PatH, P. N. Busfield, D., see Shore, P. A. Cahill, G. F., jr., see Garcia, A. 344,346,347,352,360 497,535,619,621,622,625, 372,374,375,447 Campbell, J., Rastogi, K. S. 628, 637, 638, 658 - see Renold, A. E. 390, 457 422,444 Butcher, L. L., Butcher, S. G., - see Steiner, G. 409, 459, 485, Campbell, L. B., see Thomp• Larsson, K. 853, 854, 866, 536 son, J. H. 822, 842 884 Cahn, R. S., Ingold, C. K., Pre• Campos, H. A., Parr, J. J. 426, - Engel, J. 496, 521, 853, 875, log, V. 623, 652 444 879,884 Cairncross, K. D., McCulloch, - Shideman, F. E. 217, 220 -- Fuxe, K. 496, 521 M. W., Story, D. F., Trin• Campos, H. R., Crout, J. R. - see Ungerstedt, U. 506, 537, ker, F. 783, 805 239,263 854,898 Cairns, H. J. F. 467, 521 Cannata, M. A., Chiocchio, S. Butcher, R. W., Baird, C. E., Caldeyro, R., Patetta, M. A. R., Tramezzani, J. H. 48, Sutherland, E. W. 314, 331, 114,173 49,50,73 381,382,386,444 Caldwell, J. R., see Moorhead, Cannon, B., see Hittelman, K. - Ho, R. J., Meng, H. C., E. L. 900, 901, 929 J. 412, 415, 450 Sutherland, E. W. 381, 444 Caldwell, P. C., see POl'tzehl, H. - see Lindberg, O. 409, 412, - Sutherland, E. W. 386, 444 586,614 413,453 - see Abe, K. 434, 441 Caley, D. W. 465, 521 - see Prusinger, S. B. 409, - see Bueding, E. 405,406,444 Calimlim, L. R., see Morgan, J. 412, 413, 456 - see DeRobertis, E. 427, 446 P. 871, 874, 876, 892 Cannon, P. J., see Buhs, R. P. - see Exton, J. H. 371, 374, Calissano, P., see Angeletti, P. 620,652 447 819, 829, 835 Cannon, W.B. 1,2,13 - see Handler, J. S. 433, 449 Calle, J. D., see Bhoola, K. D. - Lissak, K. 198, 221, 815, - see Jefferson, L. S. 368, 370, 99,105 836 450 Callingham, B. A. 131, 173 - Newton, H. F., Bright, E. - see Robison, G. A. 10, 15, - Cass, R. 143, 147, 173 M., Menkin, V., Moore, R. 319,334,363,367,368,392, - Mann, M. 30, 40 M. 813, 830, 836 393,395,396,405,406,407, - Sharman, D. F. 117, 147, - Nice, L. B. 800, 805 441,457,462 173 - Rosenblueth, A. 2, 13, 813, - see Sutherland, E. W. 363, - see Bowman, W. C. 515, 821,832,836 395,396,460 521, 766, 796, 803 - Uridil, J. E. 1, 13 Author Index 945

Cantin, M., see Selye, H. 425, Carlsson, A., Meisch, J. -J., Cederquist, E., see Ljungberg, 458 Waldeck, B. 498, 522, 624, 0.901,929 Capella, C., see Solcia, E. 48, 77 653 Cegrell, L. 129, 168, 173 Capon, A. 477, 521 - Rosengren, E., Bertler, A., - Falck, B. 168, 173 Cappelen, C., see Berdal, P. Nilsson, J. 5, 13, 244, 263, -- Hellman, B. 129, 173 922,923,924 336,358,814,836 -- Rosengren, A. M. 131, Carabin, S., see Poirier, L. J. - Waldeck, B. 350,358,505, 133,168,173 154,181 522,619,620,621,622,624, - see Bjorklund, A. 787, 803, - see Wiseman-Distler, M. H. 626,629,636,644,645,653 866,883 864,899 - see And{m, N. E. 199, 209, Celander, 0., Mellander, S. 271, Cardon, P. V., see Watanabe, 219,847,881 280 A. M. 864, 898 - see Bertler, A. 112, 118, 172, Celesia, G. G., Barr, A. N. 861, Cardot, J. 82,94,95,97,105 498,520 865,885 Carlson, A. D. 109 - see Seiden, L. S. 496, 535 Century, B., see Vogel, W. H. Carlson, L. A., Hallberg, D., Carlton, P. L. 498, 522 854,898 Michell, H. 387, 444 Carlyle, R. F. 81, 86, 87, 105 Cepelfk, J., see Cernohorsky, - see Havel, R. J. 491, 527 Carman, C. T., Brashear, R. E. M. 301, 331 Carlson, L. D., see Hsieh, A. C. 901,925 - see Lincova, D. 387, 453 L. 491, 528 Carmichael, E. A., Feldberg, - see Wenke, M. 291, 312, 335 Carlsson, A. 125, 156, 160, 161, W., Fleischhauer, K. 493, Cerletti, A., see Rothlin, E. 314, 173,188,221,275,280,495, 522 334 497,498,505,506,507,521, Carmichael, L., see Jasper, H. Cernohorsky, M., Cepelfk, J., 522,637,638,653,845,863, H. 476, 528 Lincova, D., Wenke, M. 866,884 Carnes, W. H. 7, 13 301,331 - Corrodi, H., Fuxe, K., Hok• - see Blaschko, H. 8, 12 - see Lincova, D. 387, 453 felt, T. 499, 522 Carpenter, D.O., see Krauss, - see Wenke, M. 291, 312, 335 -- Waldeck, B. 190, 221, K. R. 774, 777, 809 Cerny, J. C., see Harrison, T. S. 501,506,522 Carpenter, W. T., jr., see Sjo• 912,927 - Dahlstrom, A., Fuxe, K., erdsma, A. 866, 896 Cervoni, P. 816, 822, 837 Hillarp, N.-A. 211, 221, 621, Carpi, A., Oliverio, A. 814, 837 - Reit, E., McCullough, J. 622,644,653 Carr, J. R., see Duke, W. W. 726, 756 - Fuxe, K., Hamberger, B., 922,923,925 - see Kirpekar, S. M. 156, 157, Lindqvist, M. 499, 522 Carr, L. A., Moore, K. E. 466, 178,211,225,240,265,548, -- Hokfelt, T. 500, 503, 467,468,469,502,522 568,612,787,808,814,815, 504,522 Carrara, M. C., see Jori, A. 501, 817,839 -- Ungerstedt, U. 522 504,528 - see Mirkin, B. L. 766, 810 - Hillarp, N.-A. 236, 242, 249, Carregal, E. J. A., see Birzis, L. - see Wakade, A. R. 338, 362 251,263,495,504,506,522, 687,715 Cesano, L., see Feruglio, F. S. 545,546,548,551,553,560, Carson, V., see Nayler, W. G. 915,926 607 396,455 Cession-Fossion, A. 587,607 -- Hokfelt, B. 249, 263, Carstairs, K. C., see Worlledge, - Vandermeulen, R. 122,173 S. M. 861, 899 - see Bruel, van den, W. 128, 545,548,550,551,553,556, Carter, J. R., jr., see Martin, D. 159,167,173 560,607 B. 384, 454 - see Lefebvre, P. J. 915, 929 -- Waldeck, B. 204, 213, Casella, C., see Peni, V. 664, - see Vandermeulen, R. 123, 221,243,244,245,246,253, 668,674,676,677,723 158,184 259,263,337,352,357,542, Caspersson, T., Hillarp, N.-A., Cha, K. S., Lee, W.-C., Rudzik, 558,607,622,653 Ritzen, M. 17, 40 A., Miller, J. W. 127, 164, - Lindqvist, M. 149,173, 188, Cass, R., see Callingham, B. A. 173 191,192,205,221,497,506, 143,147,173 Chabrol, M., see Tournade, A. 522,618,619,623,626,631, Castaigne, P., see Boudin, G. 34,44 636,639,653,878,884 867,884 Chahl, L. A., O'Donnell, S. R. -- Dahlstrom, A., Fuxe, K. Caston, J. D. 115, 173 310,331,745,746,756 Masuoka, D. 653 Cate, J. ten, Boeles, J. T. F., Chaikoff, 1. L., see Fries, B. A. -- Fila-Hromadko, S., Cor• Biersteker, P. A. 515, 522 465,525 rodi, H. 506, 522 Cate, W. R., see Lance, E. M. Challacombe, D. N., Sandler, -- Fuxe, K., Hokfelt, T. 913,928 M., Southgate, J. 850, 885 503,504,522 Cato, J., see Pardo, E. G. 783, Challoner, D. R., Steinberg, D. -- Magnusson, T. 5, 13, 811 394,444 495,496,498,504,505,522 Caulfield, J. B., see Balogh, K. - see Hepp, D. 389, 449 --- Waldeck, B. 505, 522 923,924 Chalmers, J. P., Davies, D. S., - Lundborg, P., Stitzel, R., Causey, G., see Barton, A. A. Draffan, G. H., Reid, J. L., Waldeck, B. 620, 645, 653 689,715 Thorgeirsson, S. S. 877 - Magnusson, T., Rosengren, Cavalca, L., see Ghislandi, E. Chamberlain, M. J., see Asa- E. 517, 522 909,926 toor, A. M. 877, 881 60 Hdb. expo Pharmakol., Vol. XXXIII 946 Author Index

Chamberlin, J. A., see Fries, J. CMvez, Z. A., see Costero, 1. Chrusciel, T. L. 498,522 G. 902, 926 560,607 - see Blaschko, H. 5, 12, 188, Chambers, D. M., Roberts, D. Chi, Y.-M., see Klainer, L. M. 220,465,496,498,505,520, J.470,505,507,522 401,427,451 878,883 Chambers, J. W., Georg, R. H., - see Murad, F. 367, 371, 392, Chrysohou, A., see Wegmann, Bass, A. D. 372, 444 396, 399, 455 A. 125, 185, 815, 843 Chan, P. S., Ellis, S. 316, 331 Chiappe de Cingolani, G. E., Chu, E. W., see Wurtman, R. Chance, B., see Prusinger, S. B. see Rodbell, M. 382, 384, J. 127, 164,185 413,415,456 457 Chubb, I. W. 588, 590 Chang, C. C. 112, 173 Chiarini, C., see Muratori, G. - De Potter, W. P., De - Su, C. Y. 159,173 23,43 Schaepdryver, A. F. 576, Chang, D. K., see Tainter, M. Chiba, C., see Wegmann, A. 579,580,603.604,607 L. 336, 361 125, 185, 815, 843 - see Austin, L. 194, 219 Chang, P. 353, 358 Chichibu, S., see Libet, B. 678, Ciaranello, R. D., see Barchas, Chang, V., Rand, M. J. 765, 805 721 J. D. 119, 172 Chanussot, B., Dando, J., Mou- - see Tosaka, T. 674, 678, 707, Cicero, T. J. 488, 523 lins, M., Lavelack, M. S. 724 Civen, M., see Semba, T. 867, 101,105 Chidsey, C. A., Harrison, D. C. 896 Chapman, J., see Ruthven, C. 629,653 Clark, A. C. L., Moore, A. E., R. J. 874, 894 - Kaiser, G. A., Lehr, B. 626, Niall, M. 920, 921, 925 Chapman, R. C., Diaz-Perez, R. 653 Clark. A. J. 9, 13 901,925 - see Gaffney, T. E. 498, 525 Clark, B., see Hardman, J. G. Chase, L. R., see Granner, D. - see Harrison, D. C. 355, 358, 737, 758 369, 375, 433, 448 468,522 Clalk, C. T., see Udenfriend, S. - see Melson, G. L. 433, 454 - see Spann, J. F., jr. 159,183 186,189,229,233,268 Chase, T. N. 880, 885 Ching, T. M., see Lindberg, O. Clark, L. C., jr., see Smythies, - Schnur, J. A., Gordon, E. 409,412,413,453 J. R. 866, 897 K. 860, 885 - see Prusingel', S. B. 413, 456 Clark, M. E. 90, 91, 105 - see Brody, J. A. 847, 860, Chiocchio, S. R., Biscardi, A. Clark, R., see Grelak, R. P. 870, 884 M., Tramezzani, J. H. 23, 888 - see Mendell, J. R. 846,860, 40, 169,174, 188, 221, 922, Clark, W. G. 191, 221 862,892 925 - Drell, W. 132,174 - see Ng, K. Y. 872, 879, 893 - Tramezzani, H. H. 68 - del Giudice, J. 845, 885 - see Watanabe, A. M. 864, - see Cannata, M. A. 48, 49, - Pogrund, R. S. 191, 221 898 50, 73 - see Fleming, R. M. 149, 176 Chatten, J., Voorhess, M. L. - see Tramezzani, J. H. 17, - see Hartman, W. J. 92, 107, 917,925 44, 48, 49, 50, 52, 68, 77 188, 191,224,853,867,880, Chattopadhyay, S. K., see Chipperfield, D., see Nayler, W. 889 Brown, H. D. 392, 433, 443 G. 396, 455 - see Pogrund, R. S. 876, 879, Chavez, B., see Sourkes, T. L. Chlouverakis, C. 381, 388, 389, 893 497,536,636,658,874,897, 444 - see Schott, H. F. 188, 228, 920,921,932 Chong, G. C., Phillis, J. W. 98, 867,895 Chavez-Ibarra, G., see Her• 105 Clarke, D. D., Wilk, S., Gitlow, nandez-Peon, R. 489, 528 Chou, C., see Rose, C. M. 872, S. E., Franklin, M. J. 113, Chen, 1. L., Yates, R. D. 52, 70, 894 174 73 - see Wurtman, R. J. 874,899 Clarke, D. E., Jones, C. J. 814, -- Duncan, D. D. 52, 70, 73 Christ, D. D., Blaber, L. C. 837 Chen, J. S., see Angeletti, P. 800,805 -- Linley, P. A. 747, 756, 819,829,835 - Nishi, S. 668, 707, 716, 789, 814,837 Chen,S. S. 685,686, 716 790,791,805 Clausen, T. 383, 445 Chenoweth, M., see Schaeffer, Christenson, J. G., Dairman, - Rodbell, M. 383, 390, 445 L. D. 371, 405, 458 W., Udenfriend, S. 853, 885 -- Dunand, P. 382, 445 Cherington, M. 865, 885 Christian, B., see Banks, P. 589, - see Girardier, L. 409, 448 Cherrier, F., see Faivre, G. 911, 606 Claycomb, W. C., Kilsheimer, 926 Christian, D. R., Kilsheimer, G. S. 374, 445 Chesher, G. B., see Bevan, J. A. G. S., Pettett, G., Paradise, Clemente, C. D., see Axelrod, 567, 568, 569, 570, 606 R., Ashmore, J. 394, 395, J. 272,279, 816,835 Chessin, M., Kramer, E. R., 444 Clementi, F. 58, 73 Scott, C. C. 194, 221 Christiansen, E. N., see Grav, - Mantegazza, P., Botturi, Chester-Jones, J., see Wright, H. J. 415, 448 M. 52,58, 60, 73,778,805 A.1l6,185 Christiansen, G. S., see Caba• - Palade, G. E. 564, 607 Cheung, W. Y. 427,444 na, B. E. 906, 925 - Zocche, G. P. 600, 607 - Salganicoff, L. 427, 444 Chrojka, V. E., see Merrill, S. - see De Virgiliis, G. 563, 608 - Williamson, J. R. 392, 395, 915,929 Cline, W. H., see Twente, J. W. 396,444 Chrusciel, M. 863, 885 119,184 Author Index 947

Clower, C., see Messiha, F. S. Colville, K. 1., see Salvador, R. Cooper, J. R., see Udenfriend, 855,892 A. 286, 334 S. 186, 229, 233, 268 Clymer, N. V., Seifter, J. 512, Colwell, A. R., Bright, E. M. Cooper, K. E., Cranston, W. 1., 523 419,445 Honour, A. J. 482, 523 Coats, D. A., Emmelin, N. 817, Comline, R. S., Silver, M. 416, Cooper, R. A., see Delange, R. 837 445 J. 401, 403, 445 Cobb,J.L. S. 102,105 - see Blaschko, H. 5_ 12, 68, Cooper, T. 815, 830, 837 Cochrane, C. M., see McCurdy, 72,250,257,262,540,555, - Gilbert, J. W., Bloodwell, R. L. 646, 656 557,576,606 R. D., Crout, J. R. 815, 837 Coggeshall, R. E., see Rude, S. Commarato, M. A., Brody, T. - Willman, V. L., Jellinek, 89,96,108 M., McNeill, J. H. 337, 338, M., Hanlon, C. R. 815, 837 Cohen, A., see Cabrera, R. 764, 358 - see Coleman, H. N. 392, 445 805 Conelly, C. M. 686, 716 - see Crout, J. R. 813, 816, Cohen, G., Collins, M. 864, 885 Congiu, S., see Spano, P. F. 170, 822,837 - Goldenberg, M. 131, 174 183 - see Dempsey, P. J. 392, 445, Cohen, K. L., Bitensky, M. W. Connamacher, R. H., see Hess, 824,837 419,445 S. M. 497, 528, 636, 639, - see Musacchia, X. J. 142, Cohen, L. H., see Hagen, P. B. 654 180 224 Connett, R. J., Kirshner, N. - see Potter, L. T. 614, 813, Cohen, M. S., see Rubin, R. P. 562,607 815,816,822,830,841 124,182 - see Viveros, O. H. 540, 542, - Sjoerdsma, A. 815, 837 Cohen, P. P., see Cammarata, 551,553,556,557,558,559, - see Sobel, B. E. 392, 459 P. S. 867, 884 560,617 Cooperman, L. K., see Sjoerds• Cohen,S. 814,819, 837 Conradi, E. C., Gaffney, T. E., ma, A. 912, 931 - see Levi-Montalcini, R. 819, Fink, D. A., Vangrow, J. S. COOle, H. G., Randle, P. J. 421, 840 647,648,653 445 Cohen, Y., see Jacquot, C. 351, Consolo, S., see Buckley, G. Copp, F. C., see Boura, A. L. A. 359 662, 716 776,803 Cohn, V. H., jr., see Shore, P. A. Constantinidis, J., de la Torre, Copps, S. G., Gerritsen, T., 159,169,183 J. C., Tissot, R., Geissbuh• Smith, D. W., Waisman, Colburn, R. W., Maas, J. W. ler, F. 872, 875, 885 H. A. 852, 885 250,263 - see De Ajuriaguerra, J. 877 Corbin, J. D., Krebs, E. G. 388, - see Ng, K. Y. 872, 879, 893 - see Tissot, R. 897 445 Cole, J. 0., Wittenborn, J. R. Contractor, S. F., Panigel, M., Corbin, J. G., see Exton, J. H. 845,885 Sandler, M., Southgate, J. 371, 373, 374, 447 Colella, D. F., see Arnold, A. 871,885 Cordeau, J. P., Moreau, A., 320,321,330 Contrera, J. F., see Goldstein, Beaulnes, A., Laurin, C. Coleman, H. N., Dempsey, P. M. 192, 223, 499, 503, 526, 476,523 J., Cooper, T. 392, 445 874,888 Cordon, M. V., see Bressler, R. Coleman, M. P., Barnet, A. 862, Conway, M. J., see Werrbach, 421,423,443 875,880,885 J. H. 422, 461 Cori, C. F. 10, 13 Coleman, R. A., see Farmer, J. Cook, J. W., jr., see Entman, - see Danforth, W. H. 402, B. 301, 331 M. L. 398, 446 403,445 Coles, H., see Williamson, J. R. Cook, L., Kelleher, R. T. 478, - see Sutherland, E. W. 10,15 373,374,462 523 Cori, G. T., see Hegnauer, A.lO, Coles, H. M. T., see Anthony, Cooke, I. M. 99, 100, 105 14 P. P. 917, 919, 924 - Goldstone, M. W. 80, 100, Corkill, A. R, Tiegs, O. W. 800, Collins, G. G., S. 503, 523 101,105 805 - Pryse-Davies, J., Sandler, - see Berlind, A. 100, 105 Corne, S. J., Graham, J. D. P. M., Southgate, J. 881, 885 - see Goldstone, M. W. 99, 271,280 - Sandler, M., Williams, E. 100,107 Cornelius, J. M., see Krasner, D., Youdim, M. B. H. 858, Cools, A. R., van Rossum, J. M. N. 861, 890 869,885 854,865,885 Corrodi, H., Fuxe, K. 500, 502, - West, G. W. 165, 174, 850, Coombs, H., see Maxwell, R. A. 503,523 885 354,360,727, 760 -- H6kfelt, T. 200, 202, - Youdim, M. B. H. 6, 13 Coon, J. M., Rothman, S. 584, 221,502,523 - see Sandler, M. 858, 895 607,764,805 - Hanson, L. C. F. 501, 502, Collins, J. V., see Locke, M. 601, Coons, Levak, Miller, Wechsler 523 613 482 - Jonsson, G. 80, 105 Collins, M., see Cohen, G. 864, Cooper, C. J., de la Lande, J. Corrodi, H., Malmfors, T. 190, 885 S., Tyler, M. J. 142, 174 221 Colombo, J. P., see Donath, A. Cooper, H. A., Gunn, J. A. 868, - see Anden, N. E. 197, 198, 901, 905, 912, 913, 925 885 206, 219, 737, 756, 854, 881 Colongo, P. G., see Feruglio, F. Cooper,1. S., see Stellar, S. 861, - see Carlsson, A. 190, 221, S.915,926 865,897 499,501,506,522 60· 948 Author Index

Corvelli, A., see Reis, D. J. ll8, Couch, E. F., Arimura, A., Cranella, A., see Pick, J. 52, 76 ll9, 120, 151,182 Schally, A. V., Souto, M., Cranston, W. 1., see Cooper, K. Costa, E., Garattini, S., Valzel• Savana,S.563,607 E. 482, 523 Ii, L. 500, 523 Coulson, W. F., Bender, D. A., Crawford, A. C., see Abel, J. J. - Gessa, G. L., Kuntzman, R., Jepson, J. B. 853, 885 llO,171 Brodie, B. B. 497, 523 - Henson, G., Jepson, J. B. Crawford, J. A., Burkhalter, A. - Neff, N. H., Ngai, S. H. 632, 877,885 853,886 641,653 - see Blaschko, H. 8, 12 Crawford, J. M., see Curtis, D. - Pscheidt, G. R., van Meter, Coupar, 1. M., Turner, P. 327, R. 319, 331, 714, 716 W. G., Himwich, H. E. 496, 328,331 Crawford, T. B. B., Law, W. 523 Coupland, R. E. 16, 17, 18, 19, 170,174 - Revzin, A. M., Kuntzman, 20,21,22,23,25,26,27,29, - Outschoorn, A. S. 111, ll2, R., Spector, S., Brodie, B. 30,31,32,34,35,37,39,40, 174 B. 787, 791, 805 50,52,68,73,124,174,232, - Yates, C. M. ll2, 174 - see Bloom, F. E. 47, 64, 67, 263,539,541,550,558,563, - see Amin, A. N. 486, 518 72,828,836 564,585,586,599,600,601, - see Guldberg, H. C. 859, - see Brodie, B. B. 192, 220, 607,900,903,909,911,913, 860,888 497,521 925 - see Moir, A. T. B. 859, 872, - see Ebadi, M. S. 431, 446 - Heath, 1. D. 25, 40 892 - see Gessa, G. L. 497, 526, - Holmes, R. L. 34, 40 Crayton, J., see Weiss, B. 429, 619,636,654 - Hopwood, D. 17,25,26,41, 461 ~ see Greengard, P. 462 49,50,73 Crayton, J. W., Bloom, F. E. - see Groppetti, A. 857, 888 - Macdougall, J. D. 22, 25, 54 - see Kuntzman, R. 505, 529 30, 31, 41, 232, 263 - see Bloom, F. E. 67, 72 - see Montanari, R. 196, 226 - Mastrolia, L., Weakley, B. Credner, K., see Holtz, P. 132, - see Nash, C. W. 278, 281 S. 27,39, 41 177,188,189,224,852,875, - see Neff, N. H. 58, 76, 235, - Pyper, A. S., Hopwood, D. 889 266,499,505,533,639,657, 17,26,41,48,50,73 Crema, A., see Beani, L. 792, 848,893 - Weakley, B. S. 21, 23, 25, 803 - see Weiss, B. 427, 429,461 27, 30, 31, 36, 37, 39, 41, Cremer, G. M., Molnar, G. D., Costero, 1., CMvez, Z. A., Pe• 909,925 Moxness, K. E., Sheps, S. ralta, L., Monroy, E., Ra• - see Barber 32 G., Maher, F. T., Jones, J. m6n, F. 560, 607 - see Mrastolina 34 D. 915, 925 Cote, L. D., see Duvoisin, R. C. Couri, D., see Kirpekar, S. M. Creseitelli, F., Geissman, T. A. 867,886 548,568,612 85,106 Cottle, W. H. 491, 523 Court, J., see Mena, 1. 861, 865, Crespin, S. R., Greenough, W. - see Bligh, J. 483, 484, 486, 880,892 B., Steinberg, D. 422, 445 487,488,492,520 Coury,J., see Fisher,A. 488, 525 - see Greenough, W. B. 422, Cottrell, G. A. 82, 83, 91, 95, Coward, R. E., Smith, P., Wil• 448 96, 99, 102, 106 son, O. S. 903, 925 Creveling, C. R. 619, 639, 653 - Laverack, M. S. 85, 106 Cowell, P., Davey, M. J. 481, - Dalgard, N., Shimizu, H., - Osborne, N. N. 94, 96, 106 494, 501, 523 Daly, J. W. 857, 886 - Pentreath, V. W. 80, 102, Cowie, A. L., Kosterlitz, H. W., - Daly, J., Tokuyama, T. 106 Watt, A. J. 795, 796, 805 Witkop, B. 498, 523 - see Osborne, N. N. 82, 96, - see Kosterlitz, H. W. 795, - Levitt, M., Udenfriend, S. 97, 108 809 189,221 - seePentreath,V.W.102,108 Coyle, J. T., Snyder, S. H. 499, - Van der Schoot, J. B., Cotzias, G. C. 850, 857, 861, 885 523, 865, 870, 886 Udenfriend, S. 505, 523 - Mena, 1. Papavasiliou, P. S. - see Horn, A. S. 870, 889 - see Crout, J. R. 504, 506, 861,885 - see Snyder, S. H. 854, 865, 507,523 - Papavasiliou, P. S. 861, 867, 873,897 - see Kuntzman, R. 192, 225, 885 Crabai, F., see Gessa, G. L. 881, 505,529 -- Fehling, C., Kaufman, 887 - see Nikodijevic, B. ll2, 134, B., Mena, I. 863, 864,885 - see Spano, P. F. 170,183 149,159,181,192,227 -- Gellene, R. 860, 861, Craig, A. B., jr. 376, 445 - see Pisano, J. J. 189,227 873,874,875,885 Craig, J. W., Rall, T. W., Lar- - see Senoh, S. 823, 841, 842, --- Aronson, R. B. 880, ner, J. 401, 404, 445 856,896 885 Craig, R. J., see Laraia, P. J. - see Shimizu, H. 427, 459 -- van Woert, M. H., Sa• 395,452 - see Udenfriend, S. 495, 537 kamoto, A. 857, 885 Crain, S. M., Benitz, H., Vatter, Crispin, M., see Braham, J. 850, - van Woert, M. H., Schiffer, A. E. 819, 837 851,884 1. M. 4,13,846, 857, 860, - Wiegand, R. G. 156, 174 Crofford, O. B., see Minemura, 864,885 Cramer, W. 560, 607 T. 385, 454 - see Mena, 1. 847, 861, 865, Crammer, J. 1., Brann, A. W., Croninger, A. B., see Robins, 880, 892 Bach, L. M. N. 517, 523 E. 854, 894 Author Index 949

Cros, L., see Kabela, E. 318, Cuthbert, A. W., see Bowman, Daly, B. de B., Scott, M. J. 764, 332 W. C. 766,796,803 805 Crout, J. R. 196,217,221,274, Cyr, S. D., see Hartman, W. J. Daly, J., see Creveling, C. R. 280,338,358,506,523,750, 92,107 498,523,857,886 757,900,925 - see Nikodijevic, B. 112, 134, - Alpers, H. S., Tatum, E. L., Dacie, J. V., see Worlledge, S. 149,159,181 Shore, P. A. 625, 630, 631, M. 861, 899 - see Senoh, S. 857, 896 632, 633, 641, 653 Da Costa, F. M., see Goldberg, Daly, J. W., Axelrod, J., Wit• - Cooper, T. 813, 816, 822, L. 1. 636, 651, 654 kop, B. 857, 886 837 Dacre, J. C., Scheline, R. R., - Benigni, J., Minnis, R., Ka• - Creveling, C. R., Uden• Williams, R. T. 858, 877, naoka, Y., Witkop, B. 857, friend, S. 504, 506, 507, 523 886 886 - Muskus, A. J., Trendelen• - Williams, R. T. 877, 886 - see Shimizu, H. 427, 459 burg, U. 217, 221 338, 358, Dagirmanjian, R., Laverty, R., Daly, 1\'1. de B., Scott, M. J. 584, 468,502,523 Mantegazzini, P., Sharman, 607 - Pisano, J. J., Sjoerdsma, A. D. F., Vogt, M. 495, 496, Damasio, A. R., Antunes, J. L., 912,925 523 Macedo, C. 865, 886 - Shore, P. A. 633, 635, 653 Dahl, E., Falck, B., Lindqvist, - see Antunes, J. L. 862, 881 - Sjoerdsma, A. 902, 903, 905, M., Mecklenburg, C. v. 17, Dandiya, P. C., see Menon, M. 911, 912, 916, 92~ 925 41,82,93,106 K. 502, 531 - see Campos, H. R. 239, 263 -- von Mecklenburg, C., Dando, J., see Chanussot, B. - see Cooper, T. 815, 837 Myhrberg, H. 86, 87, 92, 95, 101,105 - see Gillespie, L. 620, 654 106 Dando, M. R., see Osborne, N. - see Gienner, G. G. 923, 926 ---- Rosengren, E. 82, N.100,108 - see Sjoerdsma, A. 189, 228 83,91,92,93,94,95,96,106 Danforth, W. H. 401, 403, 404, - see Trendelenburg, U. 338, Dahlin, D. C., see Silverman, 445 361 L. 918,931 - Helmreich, E. 401, 405, 445 Crowcroft, P. J., Holman, M. Dahlstrom, A. 60, 73, 602, 603, -- Cori, C. F. 402, 403, 445 E., Szurszewski, J. H. 688, 607 Daniel, E. E., Paton, D. M., 716 - Fuxe, K. 67, 73, 463, 523, Taylor, G. S., Hodgson, B. - Muir, T. C., Szurszewski, J. 828, 837, 847, 886 J. 406,407, 440, 445 H. 668, 674, 716 - Haggendal, J. 826, 837 Daniel, E. F., Paton, D. M., - see Blackman, J. G. 664, -- Hokfelt, T. 121, 126,157, Taylor, G. S., Hodgson, B. 668, 674, 677, 688, 715 174,216,221,566,567,569, J.319,331 - see Holman, M. E. 719 607 Daniel, H., Derry, D. M. 408, - see Szurszewski, J. H. 677, - see Adams-Ray, J. 25, 39, 445 724 133,171 - see Derry, D. M. 408, 416, Cruikshank, M., see Mandell, A. - see Anden, N. E. 847, 881 446 J.501,531 - see Bartonicek, V. 499, 520 Daniel, P. M., Henderson, J. R. Cryer, P. E., Jarett, L., Kipnis, - see Carlsson, A. 211, 221, 422,445 D. M. 382, 445 621, 622,644,653 Danish, R., see Williamson, J. Csanyi, V., Greengard, 0., - see Hillarp, N.-A. 207, 224, R. 373, 374, 462 Knox, W. E. 375, 445 463,528 D'Anzi, F. A. 596, 597,607 Csillik, B., Kalman, G., Knyi• Dahlstrom, A. B., Zetterstrom, Da Prada, M., Pletscher, A. Mr, E. 786, 787, 805 B. E. M. 576, 607 205,221,855,873,886 Cuenca, E., see Valdecasas, F. Daile, P., see Nayler, W. G. - see Bartholini, G. 496, 520, G. 354, 362 396,455 879,882 Culp, D. A., see Kirkendall, W. Dairman, W., Gordon, R., - see Berneis, K. H. 250, 252, M. 901, 928 Spector, S., Sjoerdsma, A., 262,544,558,594,606 Cunningham, A., see Eranko, Udenfriend, S. 195, 221, Daunas, J., see Penhos, J. C. 0.781,806 234,263 374, 375, 455 Cunningham, H. M. 132,174 - Udenfriend, S. 873, 886 Davey, M. J., Farmer, J. B., Cunningham, M. A., see Bel• - see Christenson, J. G. 853, Reinert, H. 272, 280 ford, J. 393, 442 885 - Hayden, M. L., Scholfield, Cunningham, W., see Wycis, Dakin, H. D. 110,174 P. C. 704, 713, 716, 776, H. T. 869, 899 Dale, H. H. 1, 9, 13, 284, 294, 805 Currie, N., see Banks, P. 589, 331 - see Cowell, P. 481, 494, 501, 606 - see Barger, G. 284, 330, 353, 523 Curry, D. L., Bennett, L. L., 357,854,882 Davidsen, G., see Laursen, T. Grodsky, G. M. 421, 445 Dalgard, N., see Creveling, C. 912,928 Curtis, D. R. 783, 805 R. 857, 886 Davies, B. M., see Brown, G. - Crawford, J. M. 319, 331, Dalgliesh, C. E., see Asatoor, A. L. 814, 836 714,716 M.189,219 Davies, B. N., Horton, E. W., - Eccles, J. C., Eccles, R. M. Daile Ore, G., see Bricolo, A. Withrington, P. G. 618, 653, 516,523 862,884 711, 716 950 Author Index

Davies, D. S., see Chalmers, D. De Iraldi, A. P., see Sabatini, Denton, R. M., see Halperin, S.877 M. T. 821, 841 M. L. 388, 389, 449 Davis, K. J., see Schayer, R. W. De Iraldi, P. A., see De Rober• De Pierre, J., see Lindberg, O. 270,272,281 tis, E. 37, 41 412,453 Davis, R. A., Drain, D. J., Hor· De Jalon, M. G., see Jalon, P. De Potter, W. P. 543, 575, 576, lington, M., Lazare, R., Ur· G. De Ill, 178 578, 579, 580, 588, 590, 608 banska, A. 192, 221 De Kalbermatten, J. P. 709, - Moerman, E. J., De Schaep• Davis, V. E., Walsh, M. J., Ya· 716 dryver, A. F., Smith, A. D. manaka, Y. 864, 886 De Koch, L. L. 24, 41 574,576,578,588,590,608 - see Walsh, M. J. 864, 898 De la Lande, 1. S., Frewin, D., - De Schaepdryver, A. F., - see Yamanaka, Y. 864, 899 Waterson, J. G., 732, 757, Moerman, E. J., Smith, A. Davis, W. G. 314, 331 833,837 D. 214, 217, 221, 574, 576, Davis, W. J., see Novales, R. - Harvey, J. A., Ill, 179 578, 588, 590, 608 R. 434, 455 - Head, R. J. 169,179 - Smith, A. D., De Schaep• Davison, A. N. 850, 886 - Jellett, L. B. 742, 743, 757 dryver, A. F. 578, 579, 604, - Sandler, M. 853, 867, 886 - Waterson, J. G. 348, 358, 608 Davoren, P. R., Sutherland, E. 732, 757 - see Chubb, 1. W. 576, 579, W.433,445 - see Cooper, C. J. 142,174 580, 603, 604, 607 Dawes, G. S., Mestyan, G. 485, - see Slarotinek, A. 901, 932 - see Laduron, P. 214, 225 491,523 - see Waterson, J. G. 780, 812 - see Smith, A. D. 555, 557, Dawkins, M. J. R., Hull, D. Delange, R. J., Kemp, R. G., 575,576,578,579,580,581, 485,491,523 Riley, W. D., Cooper, R. A., 588,589,616 Dawson, J. M. P., see Pryse. Krebs, E. G. 401, 403, 445 De Quattro, V., Maronde, R., Davies, J. 922, 923, 930 - see Riley, W. D. 404, 457 Nagatsu, T., Alexander, N. Day, M., Green, J. P. 25, 41 De la Torre, J. C. 873, 886 194,222 Day, M. D., Owen, D. A. A. Del Castillo, J., Katz, B. 714, - Sjoerdsma, A. 851, 886 2Il, 221, 571. 607 717,802,805 - see Nagatsu, T. 126, 161, - Rand, M. J. 205, 221, 498, Dell, P. 477, 524 167,180,813,816,822,840 524., 618, 631, 647, 651, 653 - see Bonvallet, M. 477, 521 De Renzo, E. C., see Kuo, J. F. Day, N., see Giarman, N. J. Della Corte, L., Perrino, 1. 8, 381, 382, 383, 452 120,176 13 De Robertis, E. 50, 54, 73, 608 Dayrit, C., see Leaders, F. E. Delluva, A. M., see Gurin, S. - De Lores Amaiz, R. G., Sal• 575, 612, 762, 765, 809 186,223 ganicopf, L., De Iraldi, P. De Ajuriaguerra, J., Gauthier, De Lores Arnaiz, R. G., see De A., Zieher, L. M. 37, 41 G., Geissbuhler, F., Simo• Robertis, E. 37, 41 - Pellegrino de Iraldi, A. 47, na, B., Constantinidis, J., Del Rio, A. E., see Rudman, 52,54,56,73,214,222 Yanniotis, G., Krassoie• D. 387, 458 -- Rodriguez de Lores Ar• vitch, M., Eisenring, J.-J., Demis, D. J., Blaschko, H., naiz, G., Zieher, L. M. 61, 73 Tissot, R. 877 Welch, A. D. 4, 13 - Rodriguez de Lores Arnaiz, Dearnaley, D. P., Fillenz, M., Dempsey, P. J., Cooper, T. 392, G., Alberici, M., Butcher, R. Woods, R. 1. 23, 41, 70, 73, 445,824,837 W., Sutherland, E. W. 427, 130,169,174 - see Coleman, H. N. 392, 446 - Geffen, L. B. 194, 197, 221, 445 - Sabatini, D. D. 248, 263, 568,607 - see Sobel, B. E. 392, 459 562, 563, 596, 599, 608 - see Blakeley, A. G. H. 568, De M. Taveau, R., see Abel, J. - Vaz Ferreira 562, 563, 596, 606 J. lIO, 171 608 - see Brown, G. L. 128, 129, Dencker, S. J., Haggendal, J., - see Alberici, M. 504, 518 173, 604, 606 Ilves-Haggendal, M. 120, - see Gerschenfeld, H. M. 466, De Castro, F. 814, 837 174 526 De Champlain, J., see Iversen, Dengler, H. 122,174 - see Pellegrino de Iraldi, A. L. L. 198, 2Il, 225 - Reichel, G. 191, 221 50,52,53,56,58,61,76 - see Landsberg, L. 195, 226 - Spiegel, H. E., Titus, E. O. - see Rodriguez de Lores Ar• De Duve, C. 563, 608 203, 208, 209, 213, 221 naiz, G. 504, 534 - see Beaufay, H. 249, 262 Denham, S., see Tsai, T. H. Derry, D. M., Daniel, H. 408, De Eds, F., Booth, A. N., Jo- 834,843 416,446 nes, F. T. 877, 878, 886 Den Hertog, A., Greengard, P., - Schoenbaum, E., Steiner, - see Masri, M. S. 857, 892 Ritchie, J. M. 691, 717 G.130,174,408,446 Degkwitz, R., Frowein, R., Ku• - Ritchie, J. M. 691, 717 - see Daniel, H. 408, 445 lenkampf, C., Mohs, V. 860, Denton, R. L., see Sourkes, T. Desalles, L., see Rabinowitz, 886 L. 874, 897,920,921,932 M. 401,456 De Groat, W. C. 710, 716 Denton, R. M., Halperin, M. L. Descarries, L. 67 - Volle, R. L. 706, 707, 708, 389,390,445 - Droz, B. 61, 67, 71, 73 716, 788, 805 - Randle, P. J. 388, 445 Dessy, S., Grandis, V. 800, 805 De Groot, J. A., see Barbeau, - Yorke, R. E., Randle, P. J. De T. Valk, A., see Koelle, G. A. 858, 882 388,445 B. 271, 281 Author Index 951

Devine, C.E. 53,56, 73, 831, 837 Dobbing, J. 464, 524 Douglas, W. W., Poisner, A. M., - Laverty, R. 56, 73 Dobbs, J. W., Robison, G. A. Trifar6, J. M. 592, 608 - Simpson, F. O. 53, 56, 58, 73 406,407,446 - Ritchie, J. M. 690, 709, 717, - see Blackman, J. G. 664, Dockry, M., Kernan, R. P., 774,806 668, 674, 677, 688, 715 Tangney, A. 798, 805 - Rubin, R. P. 583, 586, 587, De Virgiliis, G., Meldolesi, J., Dodge, F. A., Rahamimoff, R. 589,591,608,693, 717 Clementi, F. 563, 608 590,608 - see Malamed, S. 559, 596, Devrim, S., Recant, L. 420, 446 Doe, R. P., see Sarosi, G. 901, 597,613 Dewey, V. C., see Janakidevi, 931 - see Poisner, A. M. 551, 553, K. 81, 85, 107 Dolezel, D., Ziabek, K.117, 174 558,559,560,587,614,914, Dewhurst, W. G., Marley, E. Dolezel, S. 126, 174 930 464,471,474,475,496,497, Dolivo, M. 662, 717 - see Trifar6, J. 555, 558, 560, 507,512,513,524 - Koelle, G. B. 705, 717 616 Dews, P. B. 509, 524 - see Dunant, Y. 678, 681, Dousa, T., Hechter, 0., Walter, - see Smith, C. B. 496, 535 682, 717 R., Schwartz, I. L. 433, 446 - see Wurtman, R. J. 479, - see Siegrist, G. 22, 39, 44, - Rychlik, I. 405, 446 509,514,537 52,70,77,786,787,811 Doyle, A. E., see Louis, W. J. De Wulf, H., Hers, H. G. 369, Domenjoz, R., Theobald, W. 914,929 370,446 500,524 Draffan, G. H., see Chalmers, - Stalmans, W., Hers, H. G. Domer, F. R., Feldberg, W. J. P. 877 370,446 492, 493, 524 Drager, G., see Shy, M. 855, 896 Dexter, L., see Mahoney, E. M. Dominic, J. A., Moore, K. E. Dragstedt, C. A., see Griesemer, 912,929 503,524 E. C. 271,280, 752, 758 Dezza, M., see Izquierdo, J. A. Dominitz, R., see Holtzman, E. Drahota, Z., Honova, E., Hahn, 507,528 68, 75, 597, 598, 599, 600, P. 412, 446 Dhalla, N. S., McLain, P. L. 601,611 Drain, D. J., Horlington, M., 398,446 Domino, E. F., see Kissel, J. Lazare, R., Poulter, G. A. Diamond, B., see Yaryura-To• W.515, 516, 517, 529 497,524 bias, J. A. 862, 899 - see Rech, R. H. 476, 534 - see Davis, R. A. 192,221 Diamond, J., Brody, T. M. 407, Donald, J. M., see Duke, W. W. Draskoci, M., Feldberg, W.,Ha• 446 923,925 ranath, P.S.R. 464, 478, 524 - see Brody, T. M. 298, 330, Donaldson, J., see Barbeau, A. Draskoczy, P. R., Lyman, C. P. 406,443 858,882 119, 159, 170, 174 Diaz Borges, J. M., see Drujan, Donath, A., Kaser, H., Ross, - Trendelenbul'g, U. 349, 350, B. D. 141, 157,174 B., Ziegler, W., Oetliker, 0., 358,734,737,739,746,747, Diaz-Perez, R., see Chapman, Colombo, J. P., Bettex, M. 748, 749, 750, 753, 774, 775 R. C. 901, 925 901, 905, 912, 913, 925 - see Balogh, K. 923, 924 Dickens, F., see Burgen, A. S. Donath, T., see Ungvary, G. Y. - see Burack, W. R. 467, 468, V. 766, 804 128,184 521,548,550,553,606 Diner, O. 34, 41, 68, 73, 563, Donhoffer, Sz., Szelenyi, Z. 417, - see Langer, S. Z. 340, 359, 585,594,595,597,598,601, 446 727,733,734,738,747,754, 608 Donnell, G. N., see Shaw, K. N. 759, 817, 818, 833, 839 Dingell, J. V., see Gillette, J. R. F. 921, 931 - see Pluchino, S. 734, 760 499,500,526 Donoso, A. O. 144,174 - see Trendelenburg, U. 348, D'Iorio 907 - Segura, E. T. 115,174 361, 729, 730, 735, 740, 761, D'Iorio, A., Eade, N. 546, 548, Dorfman, R. I., see Hagopian, 817, 833, 843 550,608 M. 112,177 - see Weiner, N. 241, 269, - see Anderson, P. J. 858, 881 Dornsaft, H., see Rosenmund, 337, 338, 362, 914, 933 - see Blaschko, H. 249, 250, K. W. 852, 894 Drell, W., see Clark, W. G. 132, 252, 262, 539, 606 Doty, R. W., see Wyrwicka, W. 174 - see Fortier, A. 244, 264 489,537 - see Hartman, W. J. 188, - see Gelinas, R. 853, 887, Dougan, D. F. H., McLean, J. 224 902,904,906,907,908,926 R. 95, 106 - see Pogrund, R. S. 876, 879, - see Hagen, P. 244, 264 Douglas, W. W. 5, 13, 255, 256, 893 - see Kim, H. C. 6, 14 257,263,545,546,565,581, Dresse, A., see Bacq, A. M. 273, - see Leduc, J. 125, 179, 906, 583, 585, 586, 590, 608 280, 506, 519, 814, 836 907,908,928 - Kanno, T. 586, 608, 693, - see Phillipot, E. 123, 132, Dismon, G., see Wilcox, H. G. 717 158,181 372,461 -- Sampson, S. R. 585, 586, Drews, E.-F., Lindmar, R. Divaris, G. A., see Krijgsman, 589,608 Muscholl, E. 621, 625, 637, B. J. 98, 107 - Poisner, A. M. 424, 446, 549, 653 Dixon, C. W., see Van Harken, 550,560,562,584,586,589, - see Muscholl, E. 633, 657 D. R. 373, 374, 460 608 Droz, B. 602, 608 Djordjevic, N., see Hoszowska• -- Rubin, R. P. 549, 550, - see Descarries, L. 61, 67, 71, Owczarek, A. 353, 359 608 73 952 Author Index

Drudi-Baracco, C., see Halpern, Duvoisin, R. 870, 886 Ehinger, B., Falck, B. 787, 806 B. N. 496, 527 - Yahr, M. D., Cote, L. D. -- Myhrberg, H. E. 89,106 Drujan, B. D., Diaz Borges, J. 867,886 -- Persson, R. 763, 806 M.141,174 - see Yahr, M. D. 861, 867, --- Rosengren, A.-M., -- Alvarez, N. 141, 157, 899 Sporrong, B. 780, 781, 806 174 Dworkind, J., see Trifar6, J. -- Sporrong, B. 730, 757, - Sourkes, T. L., Layne, D. 539,616 778,806 S., Murphy, G. F. 121, 170, Dyce, B., see Haverback, B. J. - see Aim, P. 871, 881 174 851,889 Ehringer, R. R., Hornykiewicz, Drummond, G. 1., Duncan, L. Dziedzic, S., see Gitlow, S. E. 0.4,13, Ill, 155,174,846, 382, 396, 398, 446 845,887 848, 856, 886 -- Friesen, A. J. D. 393, -- Lechner, K. 190,222 394,398,446 Eade, N. R. 117,123,174,239, Ehrlich, P. 9 -- Hertzman, E. 392, 393, 257,263,353,358,541,546, Eiduson, S. 496, 524 395,446 548, 550, 608, 609, 907, 925 Eisenfeld, A. J., Axelrod, J., - Harwood, J. P., Powell, C. - Wood, D. R. 233, 234, 263 Krakoff, L. 209, 222, 278, A. 401, 402, 446 - see Blaschko, R. 249, 250, 280,747,748,749,757 - Powell, C. A. 401, 427, 446 252, 262, 539, 606 - Krakoff, L., Iversen, L. L., Dua, S., see Anand, B. K. 489, - see D'Iorio, A. 546, 548, 550, Axelrod, J. 278, 280 519 608 - Landsberg, L., Axelrod, J. 747,751, 757 Du Bois, F. S., see Foley, J. O. Eades, C. G., see Martin, W. R. 688,718 515,517,531 Eisenring, J.-J., see De Ajuria• Dubreuil, R., see Leduc, J. 125, Earl, A. E., see Schneider, J. A. guerra, J. 877 179 517,535 Eisenstein, A. B., Strack, 1. Duch, D. S., Viveros, O. H., Ebadi, M. S., Weiss, B., Costa, 373,446 Kirshner, N. 540, 557, 559, E. 431, 446 Eisentraut, A. M., see Unger, 608 Ebashi, S., see Ozawa, E. 393, R. H. 422, 460 Dudel, J. 692, 717 394, 403, 455 Ekelund, L.-G., see Havel, R. - Kuffler, S. W. 702, 717 Eberlein, W. R., see Young, R. J.491,527 Duggan, F., see Pellegrino de B. 920, 921, 933 Eleftheriou, B. F., see Boehlke, Iraldi 61, 76 Eberstein, A., Sandow, A. 800, K. W. 114, 136,172 Dujovne, C. A., see Rivera-Ca• Elfvin, L.-G. 22, 25, 30, 31, 34, 806 41, 52, 53, 68, 70, 71, 74, limlim, L. 871, 894 Eccles, J. C. 570, 609, 663, 665, Duke, W. W., Boshell, B. R., 564, 609, 786, 806 669, 671, 672, 676, 678, 683, - Appelgren, L. E., Ullberg, Soteres, P., Carr, J. H. 922, 685,686,687,690,699, 717 923,925 S. 31,41,52, 68, 74 - Krnjevi6, K. 694,717 Eliasson, R., Risley, P. L. 163, - Donald, J. W., Boshell, B. - see Curtis, D. R. 516, 523 R. 923, 925 175 Eccles, R. M. 664, 665, 674, 676, Elizan, T. S., see Mones, R. J. Dunand, P., see Clausen, T. 678,688,690,699,717,790, 382,445 861, 862, 866, 869, 892 806 Elliott, T. R. 1, 13, 111, 123, Dunant, Y. 676,677,686,688, - Libet, B. 678, 682, 688, 708, 175, 832, 837 690, 717 717, 783, 784, 790, 806 Ellis, S. 376, 379, 446 - Dolivo, M. 678, 681, 682, - see Curtis, D. R. 516, 523 - Kennedy, B. L., Eusebi, A. 717 Eccleston, D. 500 J., Vincent, N. R. 319, 331, - see Siegrist, G. 52, 70, 77, - see Moir, A. T. B. 859, 892 376,446 786,787,811 - see Thoa, N. B. 356, 361, - Blukoo-Allotey, J. A. 399, Duncan, D., Yates, R. 50, 52, 622,659 443 68,70,74 Echevarria, R. A., see Greer, - Chan,P. S.316,331 - see Chen, 1.-L. 52, 70, 73 M. 918, 920,921,927 - Kennedy, B. L. 440, 451 - see Garner, C. M. 23, 42 Eckhardt, S. B., see Maxwell, Ellsworth, R. C., see Stehle, R. Duncan, L., see Drummond, R. A. 130, 169, 180, 354, L. 2, 15 G. I. 382,392,393,394,395, 360,736, 760 Elmqvist, D., Quastel, D. M. J. 396, 398, 446 Edgar, P., Rabinowitz, D., 790,806 Duncombe, W. G., see Boura, Merimee, T. J. 421, 446 Elofsson, R., Kauri, T., Niel• A. L. A. 776, 803 Edwards, J. C., Howell, S. L., sen, S. 0., Stromberg, J.-O. Duner, H. 263, 479, 524 Taylor, K. W. 422, 446 99,100,106 - von Euler, U. S., Pernow, Edwards, K. D. G., see Young, Eltherington, L. G., Horita, A. B. 157, 174 J. A. 620, 660 505,524 Dunlop, D., Shanks, R. G. Edwards, R. W. R., see McKen• Emerson, O. R., see Masri, M. 320,331 drick, T. 920, 929 S.857,892 Dunn, A., see Schaeffer, L. D. Efendic, S., see Ostman, J. 386, Emery, N., see Miller, N. E. 371,405,458 387,455 488,489,532 Dupre, J., see Unger, R. R. 422, Efron, M. L., see Geiser, C. F. Emmelin, N. 733, 757 460 921,926 - see Coats, D. A. 817, 837 Author Index 953

Emmerson, B. T., see Asatoor, Erulkar, S. D., Woodward, J. Euler, U. S. v., Lishajko, F., A. M. 877, 881 K. 665, 668, 674, 677, 717 Stjarne, L. 609 Enderle, J., see Mahaux, J. E. - see Woodward, J. K. 665, - Luft, R. 202, 222, 270, 280 912,929 666,675,725 -- Sunden, T. 270, 280 Enemar, A., Falck, R, Iturriza, Erwin, V.G.,Hellerman,L. 7,13 - Purkhold, A. 126, 128, 129, F. C. 116,175 - Schnaitman, C. 6, 15 161, 166, 167,175, 198,222, Engel, A., von Euler, U. S. 912, Esayan, N. A., see Kazarova, 576, 609, 813, 815, 837 925 E. K. 128, 165,178 - Ryd, G. 129, 166,175 Engel, J., see Anden, N. E. 878, Espinosa, R. E., see Levit, S. - Stjarne, L. 639 881 A.929 - Strom, G. 22, 41, 902, 925 - Butcher, L. L. 496, 521, 853, Esplin, D. W., Heaton, D. G. - Swanbeck, G. 214, 222 875,879,884 517,524 - see Benmiloud, M. 815, 816, Engel, W. K., see Mendell, J. R. Esterhuizen, A. C., Graham, J. 836 846,860,862,892 D. P., Lever, J. D., Spriggs, - see Bloom, G. 18, 40, 113, Engelhardt, E. L., see Saari, W. T. L. R 52, 56, 58,74,729, 134,172 S. 623, 625, 658 757,779,806 - see Bygdeman, S. 190, 192, Engelman 850 - Spriggs, T. L. B., Lever, J. 220, 233, 234, 263 Engelman, K., Hammond, W. D. 52, 56, 58,74 - see Duner, H. 157,174 G. 902, 912, 925 - see Lever, J. D. 214, 226, - see Folkow, B. 479, 525 - see Horwitz. D. 850, 889 831, 833, 839 - see Gemne 215 -- Ambrose. J. M., Sjoerds- Estler, C. J., Ammon, H. P. T. - see Kaindl, F. 479, 529 ma, A. 914, 925 496,524 - see Malmfors, T. 202, 226 - Sjoerdsma, A. 914,915,925 Etsten, B. E., Shimosato, S. - see Ostlund, E. 134, 181 - seeRosenstein,B.J.918,930 911,925 - see Roth, R. H. 194, 196, - see Sjoerdsma, A. 619, 658, Ettles, M., see Anden, N. E. 228 851, 866,896, 912, 916, 931 197,198,206,219,737,756 - see Shahab, L. 201, 207, England, A. C., jr., see Schwab, Euler, C. von 486, 524 228 R. S. 869, 895 Euler, U. S. v. 2, 17,41,83,84, - see Stjarne, L. 258, 268, Ensinck, J. W., see Williams, 92, 103, 106, Ill, 113, 117, 352,361,740,760,906,907, R. H. 382, 462 119, 120, 121, 134, 135, 136, 908,932 Entman, M. L., Cook, J. W., 143,156,158,166,170,175, Eusebi, A. J., see Ellis, S. 319, jr., Bressler, R. 398, 446 193, 197, 199, 203, 205, 211, 331,376,446 - Levey, G. S., Epstein, S. E. 214,217,222,231,232,234, Evans, A., see Everett, G. M. 377,393,396,397,447 238,239,258,259,263,270, 501,524 Epps, H. M. R. 474, 524 280,539,543,544,570,571, Evarts, E. V., Gillespie, L., Epstein, D., Gunn, J. A., Vir• 581,582,604,609,619,623, Fleming, T. C., Sjoerdsma, den, C. J. 858, 886 632,903,913,914,923,925 A. 272, 280 Epstein, S. E., see Entman, M. - see Engel, A. 912, 925 Everett, G. M. 501, 524, 886 L. 377, 393,396,397,447 - Fange, R. 18,41, 113, 114, - see Scudder, C. L. 118, 182 - see Levey, G. S. 392, 393, 134, 135, 136, 137, 175 - Toman, J. E. P. 498, 524 395, 396, 397, 453 - Floding, I. 111,175 - Wiegand, R. G. 496, 505, - seeSkelton,C.L. 395, 396, 459 - Franksson, E., Hellstrom, 524 Eranko, L., see Eranko, O. 781, J. 270,275, 280, 903,925 - Will, F., Evans, A. 501, 524 806 - Gaddum, J. H. 762, 806 Everett, G. N., Borcherding, J. Eranko, O. 5, 13, 22, 41, 117, - Gemzell, C. A., Strom, G., W. 853, 875, 879 122,124,175 Westman,A.22,41,911,925 Everett, S. D., Mann, S. P.117, - Harkonen, M. 786, 806 - Hamberg, U.18,41,111,175 176 - Kauko, L. 25, 41 -- Hellner, S.170, 175,188, Evetts, K. D., Uretsky, N. J., - Lempinen, M., Raisanen, L. 222 Iversen, L. L., Iversen, S. 32,41 - Hedqvist, P. 711, 717 D. 865, 886 - Raisanen, L. 121, 122,175 - Hellner, S. 132, 170,175 Evonuk, E., see Hannon, J. P. - Rechardt, L., Eranko, L., - Hellner-Bjorkman, S. 194, 485,527 Cunningham, A. 781, 806 197,222 Exley, K. A. 776, 806 Erdosova, R., see Hruza, Z. - Hillarp, N. A. 5, 13, 50, 74, Exton, J. H., Corbin, J. G., 170,178 214,222, 542, 609 Park, C. R. 371, 373, 374, Erickson, B. W., see Green, H. - Lindner, E., Myrin, S. O. 447 504,526 482,524 - Jefferson, L. S., jr.,Butcher, Ericsson, A. D., see Honos, E. - Lishajko, F. 111, 112, 125, R. W., Park, C. R. 371, 374, 876,889 126, 129, 156, 161, 169,175, 447 Ernst, A. M. 854, 858, 863, 886 188, 189, 192, 195, 197, 199, - Park, C. R. 368, 370, 371, Erspamer, V. 133, 175 200,201,202,203,204,205, 372, 373, 376, 447 - Boretti, G. 189, 222 208,209,211, 213, 214, 216, - see Buschiazzo, H. 370, 393, - Glasser, A. 133,175 217,218,219,222,244,246, 444 - Vialli, M. 133, 175 253,257,258,263,350,352, - see Friedmann, N. 369, 372, - see Shephard,D. M. 137,183 358 373,447 954 Author Index

Exton, J. H., see Jefferson, Falck, B., see Baumgarten, H. Feldberg,W.463,465,524,592, L. S. 368, 370, 450 G. 126, 163, 172 609 - see Mallette, L. E. 372, 453 - see Bertler, A. 114, 125, 128, - Gaddum, J. H. 584, 609 Eysell, K., see Franzen, F. 845, 131, 133, 136, 147, 160, 161, - Hellon, R. F., Lotti, V. J. 887 165,166,167,172,465,496, 483,484,524 Eyzaguirre, C., see Zapata, P. 520, 872, 883 -- Myers, R. D. 483, 524 52,70,78 - see Bjorklund, A. 153, 172, - Lotti,V.J.481,482,505,524 Ezdinli, E. Z., see Frohman, L. 787,803 - Malcolm, J. L. 493, 525 A. 422, 447 - see Cegrell, L. 129, 131, 133, - Minz, B., Tsudzimura, H. 168,173 478, 525, 584, 609 Fabrykant, M., see Smith, A. - see Dahl, E. 17, 41, 82, 83, - Myers, R. D. 483, 486, 525 A. 880, 896 86,87,91,92,93,94,95,96, - Sherwood, S. L. 470, 471, Fahse, C., see Schmid, J. 505, 106 525 535 - see Ehinger, B. 89, 106, 730, - see Banerjee, U. 510, 520 Fange, R., see Augustinsson, K. 757,763,778,780,781,787; - see Carmichael, E. A. 493, B. 134,171 806 522 - see Bloom, G. 18, 40 - see Enemar, A. 116, 175 - see Domer, F. R. 492, 493, - see Euler, U. S. von 18,41, - see Hillarp, N.-A. 539, 610 524 113, 114, 134, 135, 136, 137, Falk, G. S., see Greenberg, R. - see Draskoci, M. 464, 478, 175 E. 909,911, 919,920,927 524 Fahien, L. A., see Ikeda, M. Falk, G. W., see Rosenthal, 1. Feldman, S. M., see Parker, S. 194,196,225 M.918,919,920,930 W.489,533 Fahn, S., see Schwarz, G. A. Fang, M., see Belleau, B. 7, 12 Fellman, J. H. 231, 264, 853, 862,869,895 Farber, S. 584; 609 867,887 Fain, J. N. 314, 316, 317, 319, Faredin, 1., Benko, A., Winter, Felts, P. W., see Williamson, J. 331, 382, 383, 387, 409, M., Botos, A. 130, 169, 176 R. 371, 374, 462 447 Farese, R. V., see Glinsmann, Feng852 - Loken,S. C. 384,385,447 W. H. 371,375,448 Fenster, E. D., see Fleming, R. - Reed, N. 412, 414, 447 Farmer, J. B., Coleman, R. A. M.149,176 -- Saperstein, R. 409, 447 301,331 Ferguson, B. A., see Nash, C. - see Reed, N. 409, 411, 414, - Levy, G. P. 323, 331 W.352,360 457 - Kennedy, 1., Levy, G. P., Fernandez, M. C. C., Belocopi• Fairhurst, A. S., see Hittelman, Marshall, R. J. 324, 331 tow, E. 403, 442 K. J. 414, 450 - Rand, M. J., Wilson, J. 791, Ferrans, V. J., see Beltran, G. Faivre, G., Sommelet, J., Gil· 806 924 genkrantz, J. M., Cherrier, - see Davey, M. J. 272, 280 Ferrini, R., Glasser, A. 877,878, F., Masse, G. 911, 926 Farquhar, M. G., see Smith, R. 887 Falck, B. 79, 80, 86, 87, 88, 89, E. 27, 44, 601, 616 Ferris, R. M., Viveros, O. H., 93, 99, 102, 103, 106, 121, Farrell, K. E. 53, 71, 74, 578, Kirshner, N. 244, 245, 248, 176, 786, 787, 806, 815, 609,778,806 255,257,258,259,264,595, 837 Farrugia, M. T., Hunter, W. H., 596,609 - Haggendal, J., Owman, C. Kirk, G. 624, 653 Ferry, C. B. 584, 609, 666, 690, 114, 115, 140, 176 Fassina, G. 301, 323, 331 704,718,763,765,774,806 - Hakanson, R., Owman, C., Fatt, P., Katz, B. 675, 683, 702, - see Blakeley, A. G. H. 211, Sjoberg, N.-O. 133, 176 717 213,220,569,576,606,764, - Hellman, B. 129, 176 Faull, R. L. M., Laverty, R. 767,803 - Hillarp, N.-A. 621 847,856,886 - see Brown, G. L. 814, 836 -- Hogberg, B. 249, 250, Fawcett, D. W. 598, 609 Feruglio, F. S., Greco, F., Ce• 251,264,539,609 - McNutt, N. S. 397, 447 sano, L., Colongo, P. G., -- Thieme, G., Torp, A. 5, Feher, 0., Bokri, E. 705, 718 SaI'di, G., Ghiandussi, L. 13,17,23,41,815,837 Fehling, C. 887 915,926 -- Torp, A. 125, 127, 176, - see Cotzias, G. C. 863, 864, Feustel, G., see Luppa, H. 114, 188, 190, 197, 199, 222, 246, 885 179 257,264 Fein, J., Holtz, P., Palm, D. Field, E. J., Grayson, J., Ro• - Larson, B., von Mecklen• 647,653 gers, A. F. 516, 525 burg, C., Rosengren, E., Feinberg, S. M., see Rabhun, J. Fila-Hromadko, S., see Carls• Svenaeus, K. 126, 161, 176 271,281 son, A. 506, 522 - Ljunggren, L., Nordgren, L. Feinstein, H., Schramm, M. Fillenz, M. 52, 53, 60, 74,576, 147,176 424,447 577,578,580,609,778,806 - Ljungberg, 0., Rosengren, Feinstein, M. B., see Rubin, R. - see Bisby, M. A. 588, 603, E. 901, 905, 926 P. 586, 615 606 - Nystedt, T., Rosengren, E., Fekete, M., Kurti, A. M. 854, - see Dearnaley, D. P. 23, 41, Stenfio,J. 125, 128,176 863,887 70, 73, 130, 169,174 - Owman, C. 80, 106 Felch, W. Co, jr., see Goldstein, Finch, L., Leach, G. D. H. 814, - see AIm, P. 871, 881 M. 850,888 828,837 Author Index 955

Findlay, J. A., Gill, J. R., Le· Fleming, P., Makar, H., Hun• Foroglov-Kerameus, C., see ver, J. D. 422, 447 ter, K. R. 861, 862, 887 Siegrist, G. 52, 70, 77, 786, - see Lever, J. D. 562, 563, Fleming, R. M., Clark, W. G., 787,811 612 Fenster, E. D., Towne, J. C. Forsham, P. H., see Karam, J. Findlay, J. D., Robertshaw, D. 149,176 H. 422, 451 471,484,491,525 Fleming, T. C., see Evarts, E. Fortier, A., Leduc, J., D'Iorio, Fine, M. B., Williams, R. H. V. 272, 280 A. 244, 264 373,447 Fleming, W. W. 813,832,833, Fortner, J. G., see Riley, V. 49, Finean, J. B. 592, 609 834,838 76 Fineberg, S. E., see Athos, W. - Hawkins, D. F. 314, 331 Foss, P., see Sih, C. J. 852, 896 J.915,924 - Trendelenburg, U. 340, 358, Foster, G. V. 901, 926 Fink, C. J., see Lacy, P. E. 420, 648, 659, 739, 757, 833, 838 Foster, M., Brown, S. R. 131, 421,452 - see Green, R. D., III. 327, 176 Fink, D. A., see Conradi, E. C. 328,332,726,727,730,758, Foster, R. S., see Lomax, P. 647,648,653 832, 834, 838 481,482,530 Firemark, H., see Blaschko, H. - see Morrison, J. M., jr. 833, Foster, R. W. 303, 304, 307, 26, 40, 251, 257, 262, 592, 834,840 309,310,331,730,747,748, 593,606 - see Schmidt, J. L. 337, 344, 750,757 Fischer, Iversen, L. L. 468 346, 361, 833, 834, 841 Fotino, S., Blaufox, M. D. 864, Fischer, E., Amalfara, M. L. - see Trendelenburg, U. 337, 887 471,525 343,344,345,351,362,737, Foulkes, R. G., see McGeer, P. Fischer, J. E., Horst, W. D., 747, 761, 832, 833, 843 L. 860, 861, 867, 868, 869, Kopin, I. J. 621, 626, 631, - see Tsai, T. H. 355, 362 874,891 632, 633, 642, 653 - see Urquilla, P. R. 315, 316, Fouts, J. R., see Zeller, E. A. - Kopin, I. J., Axelrod, J. 335,348,362,745,761 7,15 278,280,816,837 - see Westfall, D. P. 340, 362, Fox, L. M., see McGuire, L. B. - Musacchio, J., Kopin, I. J., 739,761 912,929 Axelrod, J. 816, 837 Fletcher, J. R. 25, 41 Frank, M. M., see Wurtman, R. - Snyder, S. 67, 74, 814, 837 Flock, E. V., see Roth, G. M. J.479,509,514,537 - Weise, V. K., Kopin, I. J. 901,930 Franklin, M. J., see Clarke, D. 618, 653, 776, 806 - see Sheps, S. G. 911, 912, 931 D.113,174 - see Kopin, I. J. 205, 208, - see Stickler, G. B. 920,932 Franksson, E., see Euler, U. S. 225,338,352,359,619,621, Floding, I., see Euler, U. S. von v. 270, 275,280, 903,925 626, 629, 633, 642, 646, 111,175 Franzen, F., Eysell, K. 845,887 655 Florey, E. 103, 106 Frati, L., see Salvi, M. L. 819, - see Musacchio, J. M. 621, Floru, R., Sterescu-Volanschi, 841 625, 632, 633, 656 M., Nestianu, V. 478, 525 Fraumeni, J. F., see Miller, R. - see Snyder, S. 271, 282, 822, Flynn, P. D., see Blecher, M. W. 917, 929 823,842 390,443 Frazer, A., Hess, M. E. 399, 447 - see Wurtman, R. J. 198, Fogel, B. J., see Tamer, A. 848, - see Shanfeld, J. 392, 395, 230, 274, 282, 431, 462, 816, 897 458 844 Foley, J. 0., Du Bois, F. S. 688, Frears, C. C., see Godwin-Au• Fischer, P., see Bacq, Z. M. 718 sten, R. B. 870, 887 167,171 Foley, T. H., Marsden, C. D., Fredholm, R, Rosell, S. 387, Fisher, A., Coury, J. 488, 525 Owen, D. A. L. 494, 525 447 Fisher, J., see Bueding, E. 405, - see Marsden, C. D. 798, 810 Freedland, R. A., see Ross, B. 406,444 Foley, T. P., jr., see Parra, A. D. 374, 458 Fizette, N. B., see Heimberg, 435,455 Freedman, D., see Barchas, J. M.367,375,449 Folkow, B. 783, 806 D.U9,172 Flacke, W., Gillis, R. A. 685, - Euler, U. S. von 479,525 Freedman, L. S., see Goldstein, 718 - Haggendal, J., Lisander, B. M. 873, 888 - see Fleisch, J. H. 685, 718 216,223,240,264,566,567, Freeman, B. M. 485, 491, 525 - see Gillis, R. A. 685, 718 568,569,609 Freidberg, S. L., see Klainer, Flatt, J. P. 389, 390, 447 - Haeger, K., Uvnas, B. 762, L.M. 401, 427,451 Fleckenstein, A. 336, 358 806 French, J. E., see Woodin, A. - Bass, H. 336, 337, 343, 358, Fonnum, F., Larsen, K. 867, M. 584, 617 737, 757, 833, 837 887 Frerichs, H., Ball, E. G. 388, - Burn, J. H. 336, 337, 358, Foo, J. W., Jowett, A., Staf• 447 737,757 ford, A. 307; 331 Frewin, D., see De la Lande, I. - Srockle, D. 336, 337, 351, Forbes, A., see Therman, P. O. S. 732, 757, 833, 837 358,737,767 663,724 Frey, H. H. 742, 752, 757 Fleisch, J. H., Flacke, W., Gil· Forgrave, P., see Hemingway, Friedhoff, A. J., van Winkle, E. lis, R. A. 685, 718 A. 494, 528 850,887 Fleischhauer, K., see Carmi• Forland, M., see Lawrence, A. - see Goldstein, M. 112, 170, chael, E. A. 493, 522 M.915,928 177,874,888 956 Author Index

Friedman, A. H., Bhagat, B. Fuller, A. M., Brown, H. A., Fuxe, K., see Carlsson, A. 211, 142,160,176 Harrison, E. G., Siekert, R. 221,499,500,503,504,522, - Walker, C. A. 119,176 G. 923, 926 621, 622, 644, 653 Friedman, B., Goodman, E. H., Fuller, R. W., Hunt, J. M. 231, - see Corrodi, H. 200, 202, jr., Weinhouse, S. 370, 447 264 221,500,502,503,523 Friedman, S., see Kaufman, S. Funk, C. 852, 887 - see Dahlstrom, A. 67, 73, 189,225 Furchgott, R. F. 284, 285,286, 463, 523, 828, 837, 847, 886 Friedmann, N., Exton, J. H., 288,289,292,293,295,2£6. - see Goldstein, M. 888 Park, C. R. 369, 373, 447 298,299,300,301,302,303, - see Hillarp, N.-A. 207, 224, - Park, C. R. 376, 377, 447 305,306,313,314,315,316, 463,528 Friend, G., Zileli, M. S., Ham• 317,318,323,327,332,746, - see Ungerstedt, U. 506, 537, lin, J. R., Reutter, F. W. 757, 787, 808, 814, 838 854,898 271,280 - Bhadrakom, S. 295, 296, Friend, O. G., see Mahoney, E. 332 Gabay, S., see George, H. 851, M. 912, 929 - Bursztyn, P. 289, 292, 332 887 Fries, B. A., Chaikoff, 1. L. 465, - Kirpekar, S. M. 303, 304, Gabella, G. 52, 74, 795, 796, 525 332,353,354,358 806 Fries, J. G., Chamberlin, J. A. -- Rieker, M., Schwab, A. Gaddum, J. H. Ill, 176, 509, 902,926 212,223,303,332,634,654, 525,708,718 Friesen, A. J. D., Allen, G., Va• 730,731,757 - Schild, H. 2, 13 ladares, J. R. E. 394, 398, - Sanchez Garcia, P. 634, 654, - see Amin, A. N. 486, 518 447 742, 757 - see Barsoum, G. S. 111,172 - Oliver, N., Allen, G. 394, - Weinstein, P., Huebl, H., - see Euler, U. S. von 762, 806 398,447 Bozorgmehri, P., Mensen• - see Feldberg, W. 584, 609 - see Drummond, G. 1. 393, diek, S. R. 271, 280, 742, Gaffney, T. E., Chidsey, C. A., 394,398,446 752, 757 Braunwald, E. 498, 525 Friesen, H., see Barbeau, A. - see Besse, J. 289, 292, 293, - see Conradi, E. C. 647, 648, 862,882 297,330 653 Frist, T. F., see Riddell, D. H. - see Kirpekar, S. M. 156, 157, - see Mohammed, S. 647, 656 901,930 178,354,359,787,808,814, - see Sugarman, S. R. 646, Froede, H., see Burn, J. H. 815,817,839 648,651,659 767,804 - see Levin, J. A. 304, 333, Gage, P. W., Hubbard, J. 1. Frohlich, A., Loewi, O. 336, 752, 759 694,718 358 - see Wakade, A. R. 338, 362 Gagliardino, J. J., Hernandez, Froesch, E. R. 381, 447 Furneaux, P. J. S., McFarlane, R. E., Rodriguez, R. R. 421, Frohman, L. A., Ezdinli, E. Z., J. E. 84, 99, 106 447 Javid, R. 422, 447 Furness, J. B. 731, 757 Gagnon, D. J., Melville, K. 1. Fromageot, C., Jutisz, M., Le- Fuwa, K., see Borowitz, J. L. 494, 511, 525 derer, E. 112,176 251,262 Galambos, E., see Pfeifer, A. K. Frontali, N. 100, 106 Fuxe,K. 74, 188,223,463,525 504,533 - Haggendal, J. 84, 99, 106 - Goldstein, M., Ljungdahl, Galambos, R., see Therman, P. - Norberg, K.-A. 100, 106 A. 870, 887 0.663,724 - see Mancini, G. 54, 64, 75, - Hamberger, B., Malmfors, Gale, C., see Andersen, H. T. 101,107 T. 499, 525 490,519 Frowein, R., see Degkwitz, R. - Hillarp, N.-A. 499, 525 Gale, C. C., see Werrbach, J. H. 860,886 - Hokfelt, B., Nilsson, O. 37, 422,461 Fiilgraff, G., Heidenreich, 0., 41, 46, 61, 67, 71, 74, 866, Gallagher, J. P., Blaber, L. C. Heintze, K., Osswald, H. 887 802,806 319,331 --- Reinius, S. 46, 61, - see Blaber, L. C. 800, 803 Fuenzalida, S., see Mena, 1. 67,74 Gamo, T., see Sano, 1. 118, 155, 847, 861, 865, 880, 892 -- Ritzen, M., Ungerstedt, 182 Fugazza, J., see Beauvallet, M. U. 467, 525 Gang, H., see Goldstein, M. 118,172 - Sedvall, G. 131, 176, 831, 903,926 Fujimoto, S., see Iwata, H. 167, 833,838 Gannon, B., Burnstock, G. 136, 178 - Ungerstedt, U. 466, 499, 176 Fujiwara, M., Tanaka, T., Hi• 500,525 Garattini, S., Giachetti, A., Jo• roshi, H., Okegawa, T. 129, - see Adams-Ray, J. 25, 39, ri, A., Pieri, L., Valzelli, L. 166,176 133,171 500,525 Fukami, M., see Williamson, J. - see Anden, N.-E. 149,171, - see Bonaccorsi, A. 732, 756 R.409, 412, 413, 414, 415, 641,642,652,847,854,878, - see Costa, E. 500, 523 462 881 - see Jori, A. 501, 504, 528 Fukase, M., see Imura, H. 435, - see Angelakos, E. T. 125, - see Valzelli, L. 118, 149,184 450 159,171,188,201,219 Garcia, A., Williamson, J. R., Fulk, M. E., MacLeod, J. J. R. - see Bartonicek, V. 499, 520 Cahill, G. F., jr. 372, 374, 123,176 - see Butcher, L. L. 496, 521 375,447 Author Index 957

Gardiner, J. E., Hellmann, K., Geissbuhler, F., see Constan• Gewirtz, G. P., Kopin, I. J. Thompson, J. W. 767, 806 tinidis, J. 872, 875, 885 575,579,609 - Thompson, J. W. 763, 765, - see De Ajuriaguerra, J. 877 Gey, K. F. 876, 887 806 Geissman, T. A., see Crescitelli, - Burkard, W. P., Pletscher, Gardner, F. T., see Applewhite, F. 85, 106 A. 853, 867, 887 P. B. 81, 85, 105 Gejrot, T., LagerlOf, B., Wer• - Messiha, F. 867, 887 Gardner, L. I., see Greenberg, saIl, J. 923, 926 - see Bartholini, G. 235, 262, R. E. 918, 919, 921, 927 Gelehrter, T. D., see Tomkins, 851,876,882 - see Voorhess, M. L. 920, G. M. 375, 460 - see Burkard, W. P. 814, 921,933 Gelinas, R., Pellerin, J., D'Io• 836,862,884 Garfield, J. M., see Gillis, R. A. rio, A. 853, 887, 902, 904, - see Pletscher, A. 504, 506, 685,718 906, 907, 908, 926 533,814,841 Garg, K. N., see Allen, D. J. Gellene, R., see Cotzias, G. C. - see Schwartz, D. E. 499, 535 491,492,493,518 860,861,873,874,875,880, - see Thoenen, H. 160, 167, Garland, H., Pearce, J. 848, 887 885 184,504,536,620,621,625, Garland, P. B., Haddock, B. A., Gemne, Euler, U. S. v. 215 626,627,628,629,632,633, Yates, D. W. 415, 448 Gemzell, C. A., see Euler, U. S. 643,646,650,659,823,842, - Randle, P. J. 402, 448 v. 22,41, 91I, 925 875,897 - see Randle, P. J. 402, 456 Genest, J., Simard, S., Rosen• Geyer, M., see Van Orden, III, Garner, C. M., Duncan, D. 23, thal, J., Boucher, R. 130, L. S. 786, 787, 812 42 169,176 Ghiandussi, L., see Feruglio, F. Garrett, J., Osswald, W.,Rodri• - see Barbeau, A. 864, 882 S. 915, 926 gues-Pereira, E., Guimara• Gennaro, J. F., see Anton, A. Ghidoni, J. J., see Mayfield, E. es, S. 914, 926 H. 1I6, 142,171 D., jr. 425, 426, 454 Garvey, III. T. Q., see Gold• Georg, R. H., see Chambers, J. Ghiretti, F. 92, 106 stein, M. 196,223 W.372,444 Ghislandi, E., Guidotti, G., Ca• Garvin, J. S., see Klawans, H. George, H., Gabay, S. 851, 887 valca, L. 909, 926 L., jr. 869, 872, 890 Gerard, R. W., see Kosman, M. Ghosh, A. 1I7, 176 Gaskell, J. F. 89, 91, 106 E. 479, 529 Giachetti, A., Shore, P. A. 208, Gasner, L. T., see Griesemer, E. - see Sigg, E. 515, 535 223,352,358 C.496,527 Gerber, H., see Goldstein, M. - see Garattini, S. 500, 525 Gasser, H. S., see Grundfest, H. 467,469,526 - see Shore, P. A. 209, 228, 691, 718 Gerbode, F., see Bowers, M. B., 621,622,654 Gaudreau, P., see Barbeau, A. jr.846,860,862,884 Giacobini, E., see Buckley, G. 858,882 Gerold, see Haeusler 831 662,716 Gaunt, R., see Schneider, J. A. Gerritsen, T., see Copps, S. G. Giacomini, E. 17,42 517,535 852,885 Giarman,N.J., Day,N.120,176 Gauthier, G., see De Ajur-ia• Gerschenfeld, H. M. 95, 106 - see Bloom, F. E. 46, 52, 56, guerra, J. 877 - Tauy, L. 98, 106 58, 60, 72, 319, 330 Gautron, J., see Taxi, J. 787, - Wald, F., Zadunaisky, J.A., - see Pepeu, G. 871, 893 812 de Robertis, E. P. D. 466, - see Roth, R. H. 50, 53, 71, Gavitt, J., see Smith, A. A. 880, 526 77, 235, 267, 902, 904, 916, 896 Gerschman, R., see Houssay, 930 Gebber, G. L. 687, 700, 703, B. A. 140, 178 - see Stjarne, L. 53, 68, 77, 718 Gerstenbrand, F. 862, 887 198,201, 213, 229, 240, 268 - Snyder,D. W. 706, 707, 718 - Griindig, E. 879, 887 - see Van Orden, L. S. 46, 53, - Volle, R. L. 685, 686, 697, - see Bruck, H. 850, 884 56,58,60,78,570,571,616, 701, 706, 718 Gertner, S. B., Reinert, H. 689, 634, 660, 815, 843 Geffen, L. B. 200, 212, 223, 240, 718 Gibb, J. W., Webb, J. G. 851, 264 Gessa, G. L., Costa, E., Kuntz• 887 - Livett, B. G. 543, 574, 602, man, R., Brodie, B. B. 497, Gibbons, W. R., see Burn, J. H. 609 526, 619, 636, 654 588,607,767,774,778,781, -- Rush, R. A. 74, 217, - Vargiu, L., Crabai, F., Boe• 782,804 223, 574, 575, 602, 609 ro, G. C., Caboni, F., Cam• Gibson, J. E., see Scudder, C. - Ostberg, A. 60, 74, 543, 602, ba, R. 881, 887 L. 1I8, 182 603, 609, 826, 838 - see Costa, E. 497, 523 Gibson, W. C., see McGeer, P. - Rush, R. A. 602, 604, 609 - see Sjoerdsma, A. 866, 896 L.860, 861, 867, 868, 869, - see Brown, G. L. 128, 129, - see Spano, P. F. 170,183 874,891 173,604,606 - see Tagliamonte, A. 866, Gifford, R. W., Kvale, W. F., - see Dearnaley, D. P. 194, 897 Maher, F. T., Roth, G. M., 197, 221, 568, 607 Gessa, R., see Spano, P. F. 170, Priestley, J. T. 900, 926 - see Livett, B. G. 574, 602, 183 - see Pontasse, E. F. 914, 915, 613 Gessner, O. 114, 176 930 Geiser, C. F., Efron, M. L. 921, Gevers, W., Krebs, H. A. 372, - see Priestley, J. T. 901, 911, 926 377,448 930 958 Author Index

Gigee, W., see Raab, W. 170, Girardier, L., Seydoux, J., Glowinski, J., Kopin, 1. J., Axel• 181, 197, 206, 228, 816, 841 Clausen, T. 409,448 rod,J.50,74,198,218,223, Gij6n, E., see Pardo, E. G. 783, Gitlow, S. E., Bertani, L. M., 467,468,469,504,526 811 Wilk, E., Li, B. L., Dzied• - Snyder, S. H., Axelrod, J. Gilbert, J. W., see Cooper, T. zic, S. 845, 887 218,223,467,468,526 815,837 - Mendlowitz, M., Kruk, E., - see Iversen, L. L. 198, 208, Giles, R. E., Miller, J. W. 164, Khassis, S. 912, 926 209,211,212,218,225,278, 176, 506, 526, 750, 758 - see Clarke, D. D. 113, 174 281,467,468,469,528,570, Giles, R. H., jr., see McKinney, - see Mendlowitz, M. 845, 892 611,813,814,816,820,821, T. D. 122,180 - see Pertsemlidis, D. 901, 822, 828, 830, 831, 834, 839 Gilfrich, H. J., see Rahn, K. H. 913,930 - see Milhaud, G. 467, 532 646, 648, 658 del Giudice, J., see Clark, W. - see Reivich, M. 466, 534 Gilgenkrantz, J. M., see Faivre, G. 845, 885 Godwin-Austen, R. B., Frears, G. 911, 926 Gjessing, L. R. 620, 654, 845, C. C., Bergmann, S., Par• Gill, J. R., see Findlay, J. A. 852,853,887,900,912,913, kes, J. D., Knill-Jones, R. 422,447 918,919,920,921,926 P. 870, 887 Gilles, C. N., see Hughes, J. - Borud, O. 921, 926 Giiriig, P., Szporny, L. 165, 176 203,225 - Mauritzen, K. 921, 926 Goetzl, F. R., see Ivy,A. C. 471, Gillespie, J. S. 198, 203, 204, - see O'Gorman, L. P. 866, 528 223 874,876,893 Goffart, M. 796, 797, 800, 807 - Hamilton, D. N. H. 747, Gladstone, G. P., Van Heynin• - Brown, G. L. 800, 807 758 gen, W. E. 584, 610 - Holmes, D. 708, 718 -- Hosie, R. J. A. 748, 758 Glaser, A., see Erspamer, V. - Perry, W. L. M. 798,807 - Kirpekar, S. M. 176, 199, 133,175 - Ritchie, J. M. 797, 807 202,209,210,223,568,576, - see Ferrini, R. 877,878,887 - see Brown, G. L. 796, 797, 609,610 - see Mantegazzini, P. 496, 798, 799, 800, 804 - Mackenna, B. R. 210, 223, 531 - see Phillipot, E. 123, 132, 763,807 Glagov, S., see Wolinsky, H. 158,181 - Muir, T. C. 748, 758, 828, 831,844 Gokhale, S. D., see Gulati, O. 838 Glaizner, B., see Walker, R. J. D. 299, 314, 315, 332 - see Avakian, O. V. 204, 219, 97,98,109 Golan, R., see Braham, J. 850, 747,749, 756 Glassman, P. M., see Angelakos, 851,884 - see Brown, G. L. 211, 220, E.T. 115, 137, 139, 140,171 Gold, A. H. 370, 448 240,262,271,280,753,756 Glees 783 Goldberg, A. A. J., see Bow• Gillespie,L., Oates,J.A., Crout, Glenner, G. G., Crout, J. R., man, W. C. 796, 797, 798, J. R., Sjoerdsma, A. 620, Roberts, W. C. 923,926 804 654 - see Grimley, P. M. 52, 70, Goldberg, A. L., Singer, J. J. - see Evarts, E. V. 272, 280 74,922,923,927 401,402 448 - see Oates, J. A. 191, 227, Glinsmann, W. H., Hern, E. P. Goldberg, L. 1., Da Costa, F. 618,657 370, 371, 448 M., Ozaki, M. 636 651, 654 Gillette, J. R., Dingell, J. V., -- Linarelli, L. G., Farese, - Sonneville, P. F., McNay, Sulser, F., Kuntzman, R., R. V. 371, 375, 448 J. L. 863, 887 Brodie, B. B. 499, 500, 526 - Mortimore, G. E. 372, 376, - Yeh, B. K. 854, 887 Gillingham, F. J., see Guldberg, 448 - see Horwitz, D. 863, 869, H. C. 859, 888 - see Klein, D. C. 429, 430, 889 - see Pullar, 1. A. 859, 872, 451 - see McNay, J. L. 854, 891 873,894 Glisson, S., see Shah, N. S. 852, - see Yeh, B. K. 854, 899 Gillis, C. N., see Sears, M. L. 896 Goldberg, N. D., O'Toole, A. G. 817,841 Glisson, S. N., see Agrawal, H. 428,448 - see Simmonds, M. A. 747, C. 118,171 - Villar-Palasi, C., Sasko, H., 748,749,760 Glowinski, J., Axelrod, J. 198, Larner, J. 404, 448 Gillis, R. A., Flacke, W., Gar· 208,210,212,213,218,223, - see Larner, J. 404, 452 field, J. M., Alper, M. H. 278,280,467,497,499,500, Golden, R. L., Mortati, F. S., 685, 718 505,507,526 Schroeter, G. A. 868, 887 - see Flacke, W. 685, 718 -- Iversen, L. 500, 505, 526 Golden, R. M., see Leon, A. S. - see Fleisch, J. H. 685, 718 -- Kopin, 1. J., Wurtman, 873,891 - see Varma, D. R. 338, 362 R.J.465, 526, 820, 838 Goldenberg, M., see Cohen, G. Gillo-Joffroy, L., see Barbeau, - Baldessarini, R. J. 270, 280, 131,174 A. 864, 882 468,504,526 Goldfarb, A., see Sacks, O. W. Ginsborg, B. L. 705, 706, 718 - Iversen, L. L. 118, 149176, 865,895 - Guerrero, S. 695, 698, 699, 466,467,468,495,497,498, Goldfien, A., Zileli, S., Good• 718 499, 504, 526, 621, 622, 655 man, D., Thorn, G. W. 911, - see Blackman, J. G. 664, -- Axelrod, J. 193, 223, 926 666,669,670,671,672,673, 236,264,466,467,468,495, Goldhaber, P., see Wells, H. 674, 675, 677, 695, 715 497,498,499,504,526 425,461 Author Index 959

Goldhammer, Y., see Braham, Gonzalez-Vegas, J. A., Wol• Gordon, R. S., see Hertelendy, J.863,884 stencroft, J. H. 10, 13 F. 422, 449 Goldman, J. M., Hadley, M. E. Goodall, McC. 4, 13, 121, 122, Gordon, R. S., jr., see Wolfe, S. 448 125. 158. 159, 160, 177, 188, M. 423, 462 - see Hadley, M. E. 434, 448 198,223,813,815,838,852, Gordon, W., see Kuttner, R. Goldman, R., see Harrison, D. 888 465,529 C.355,358 - Alton, H. 855, 888 Gorgas, K. 29, 42 Goldstein, L., Munoz, C. 477, - Harlan, W. R., jr., Alton, H. Gorin, E., Shafrir, E. 388, 389, 508,526 855,888 448 Goldstein, M. 467, 469, 507, - Kirshner, N. 4, 13,187, 188, Gosselin, L., see Bacq, A. M. 526, 902, 917, 926 223, 815, 838 273, 280, 506, 519, 814, 836 - Anagnoste, B. 628, 654 - Stone, C. 901, 926 Goto, K., see Kasuya, Y. 727, -- Goldstein, M. N. 917, - see Kirshner, N. 31, 42, 231, 738, 759 926 265 Gottesman, K. S., see Miller, N. -- Lauber, E., McKereg• Goodchild, M. A. 503, 526 E. 488, 489, 532 han, M. R. 193, 201, 223, Goodland, G. A. J., see Kirpe• Gottfries, C. G., Gottfries, I., 503,526,814,838 kar, S. M. 548, 612 Roos, B. E. 856, 860, 888 -- Nakajima, K. 501, 526 Goodman, D., see Goldfien, A. - see Bertler, A. 147, 172 -- Owen, W. S., Battista, 911,926 Gottfries, I., see Gottfries, C. A. F. 847, 850, 887 Goodman, E. H., jr., see Fried- G. 856, 860, 888 -- Yamamoto, A., Felch, man, B. 370, 447 Gourley, D. R. H., Bethea, M. W. C., jr. 850, 888 Goodman, H. M. 385, 448 D. 383, 448 - Battista, A. F., Nakatini, - Bray, G. A. 390, 448 Govier, W. C. 298, 319, 327, 332 S., Anagnoste, B. 847, 863, - see Bray, G. A. 390, 443 - Boadle, M. C. 592, 610 874,880,888 Goodman, L. S., see Nickerson, - Lovenberg, W., Sjoerdsma, - Contrera, J. F. 192, 223, M.9,14 A. 423, 448 499,503,526 Goodner, C. J., see Werrbach, - Mosal, N. C., Whittington, - Freedman, L. S., Back• J. H. 422, 461 P., Broom, A. H. 298, 332 strom, T. 873, 888 Goodwin, B. L. 875, 878, 888 - Sugrue, M. F., Shore, P. A. - Friedhoff, A. J., Pomerantz, - Karoum, F., Ruthven, C. R. 731,758 S., Contrera, J. F. 874, 888 J., Sandler, M. 858, 866, 888 Govyrin, V. A. 131, 170, 177 -- Simmons, C. 112, 170, - see Sandler, M. 878,895 Govyrin, W. A., see Plotnikova, 177 Goodwin, F. K., Brodie, H. K. S. N. 86, 108 - Fuxe, K., Battista, A. F., H., Murphy, D. L., Bunney, Graber, A., see Porte, D. 419, Backstrom, T., Nakatani, S. W. E., jr. 846,859,862,865, 422,456 888 871, 872, 874, 875, 888 Graefe, K. H., Bonisch, H., - Gang,H.,Joh,T.H.903,926 - seeTamarkin,N.R.860,897 Trendelenburg, U. 740, 741, - Gerber, H. 467, 469, 526 Gordon, B., see Bondareff, W. 742, 758 - Joh, T. H., Garvey, III., T. 52,58,73 - Trendelenburg, U. 9, 13, Q.196,223 Gordon, E., see Axelrod, J. 338, 342,361,728,738,739,746, - Lauber, E., McKereghan, 357 758 M. R. 189, 193, 223, 503, Gordon, E. K., see Brody, J. A. - see Trendelenburg, U. 751, 506,526 847, 860, 884 752, 754, 761 - McKereghan, M. R., Lau- - see Chase, T. N. 860, 885 Graeff, F. G. 506, 526 ber, E. 624, 654 - see Kopin, I. J. 209, 210, Graeff, J. de, Horak, B. J. V. - Nakajima, K. 503, 526 217,218,225,274,275,276, 901,926 - Weiss, Z. 189, 190, 223 277,278,281,502,529,816, Graf,N., seeSchmid,E. 914,931 - see Anagnoste, B. 881 839 Graham, J. D. P. 919, 926 - see Battista, A. F. 847, 882 Gordon, M. F., see Rapela, C. - Lever, J. D., Spriggs, T. L. - see Fuxe, K. 870, 887 E. 115,182 B. 53, 56, 74, 584, 610, 780, - see Musacchio, J. M. 189, Gordon, P., see Scheving, L. E. 807 227, 503, 532, 619, 626, 656 119,182 - see Corne; S. J. 271, 280 Goldstein, M. N., see Goldstein, Gordon, R., Reid, J. V. 0., - see Esterhuizen, A. C. 52, M. 917, 926 Sjoerdsma, A., Udenfriend, 56,58,74,729,757,779,806 Goldstein, R., see Rosenthal, I. S.194,223 - see Lever, J. D. 46, 53, 56, M.903,905,909,930 - Spector, S., Sjoerdsma, A., 58, 75 Goldstone, M. W., Cooke, I. M. Udenfriend, S. 194, 223, Gram, T. E., Wright, H. N. 622, 99,100,107 234,237,264 625, 638, 648, 654 - see Berlind, A. 100, 105 - see Dairman, W. 195, 221, Grand, R. J. 425,448 - see Cooke, I. M. 80, 100, 234,263 - Gross, P. R. 425, 448 101,105 - see Spector, S. 194, 228, Grandis, V., see Dessy, S. 800, Gomez, H., see Mohammed, S. 235, 268, 639, 658 805 647,656 - see Udenfriend, S. 497, 501, Granner, D., Chase, L. R., Gonnard, P., see Schmitt, H. 503,537,619,627,637,639, Aurbach, G. D., Tomkins, 742 752, 760 660 G. M., 369, 375, 433, 448 960 Author Index

Granner, D., see Tomkins, G. Greer, M. 866, 888 Griindig, E., see Gerstenbrand, M.375,460 - Anton, A. H., Williams, C. F. 879, 887 Grant, R., see Andersson, B. M., Echevarria, R. A. 918, Grunden, L. R. 470, 471, 476, 494,519 920,921,927 508,512,527 Grasso, S. G., see Karam, J. H. - Sprinkle, T. J., Williams, C. - Katzung, B. G. 470, 471, 422,451 M.913,921,927 479,527 Grav, H. J., Pedersen, J. I., - Williams, C. M. 855, 860, - Marley, E. 470, 471, 472, Christiansen, E. N. 415, 448 888 474,485,512,527 Gray, S. J., see Resnick, R. H. - see Anton, A. H. 852, 881, Grundfest, H., Gasser, H. S. 880,894 905, 9Il, 913, 918, 924 691,718 Grayson, J., see Field, E. J. Greer, W. E. R.,Robertson, W., Grynszpan-Winograd, O. 563, 516,525 Smithwick, R. H. 901, 927 585,594,595,597,610 Greco, F., see Feruglio, F. S. Grelak, R. P., Clark, R., Guerinot, F., see Bohuon, C. 915,926 Stump, J. M., Vernier, V. 902,913,917,918,924 Greeff, K., Strobach, H. 912, G. 870, 888 Guerrero, S., see Ginsborg, B. 920,926 Griesemer, E. C., Barsky, J., L. 695,698,699, 718 Green, A. A., see Page, I. H. Dragstedt, C. A., Wells, J. Guther, W., see Schumann, H. Ill, 181 A., Zeller, E. A. 271, 280, J. 730, 760 Green, A. I., see Snyder, S. H. 752,758 Gueudet, R., see Pellegrino de 500,535 - Gasner, L. T. 496, 527 Iraldi, A. 53, 56, 58, 60, 76 Green, A. F., see Boura, A. L. Grillo, M. A. 22, 42, 46, 52, 56, Guggenheim, M. 852, 888 A.776,803,814,836 60,67,70,71,74,778,786, Guggenheim, S., see Bourgoi• Green, D. E., Richter, D. 8, 13 787,807,920,927 gnie, J. 443 Green, H., Erickson, B. W. 504, - Palay, S. L. 47, 52, 54, 56, Guidotti, G., see Ghislandi, E. 526 60, 71, 74, 778, 807 909,926 Green, J. 861, 888 Grimley, P. M., Glenner, G. G. Guillard, A., see Boudin, G. 867, Green, J. H., Heffron, P. F. 52,70,74,922,923,927 884 664,718 Grivel, M. L., see Ruckebusch, Guimaraes, S., Osswald, W. - see McCubbin, J. W. 709, 1[.482,484,491,534 327,332 722 de Groat, W. C., see Takeshige, - see Garrett, J. 914, 926 Green, J. P. 216, 223 C.704,724 Gulati, O. D., Gokhale, S. D., - see Day, M. 25, 41 Grobecker, H. 662, 718 Parikh, H. M., Udwadia, B. Green, R. D., III., Fleming, W. - Holtz, P. 619, 628, 654 P., Krishnamurty, V. S. R. W. 327, 328, 332, 726, 727, -- Jonsson,J. 341, 358 299, 314, 315, 332 730, 758, 832, 834, 838 -- Muller, H. K. Il5, 140, Gulati, O. S., Kelkar, V. V. 339, - Miller, J. W. 127,177 177, 619, 628, 637, 654 358 - see Bristow, M. 310, 312, -- Palm, D., Bak, I. J., Guldberg, H. C., Ashcroft, G. 313, 323, 324, 330 Hassler, R. J. 587, 590, 610 W., Crawford, T. B. B. 860, Greenawalt, J. W., see Schnait• - see Schumann, H. J. 192, 888 man, C. 6,15 228,619,623,627,637,644, - Turner, J. W., Hanieh, A., Greenberg, M. J. 98, 107 658 Ashcroft, G. W., Crawford, Greenberg, R. E., Gardner, L. Groblewski, G. E., see Lands, T. B. B., Perry, W. L. M., I. 918, 919, 921, 927 A. M. 320, 324, 325, 333 Gillingham, F. J. 859, 888 - Lind,J. 21, 22, 42 Grodsky, G. M., Bennett, L. L. - see Moir, A. T. B. 859, 892 - Rosenthal, I., Falk, G. S. 421,448 Gumulka, W., Szreniawski, Z. 909,911,919,920,927 -- Smith, D.F., Schmid,F. 701,718 - see Rosenthal, I. M. 903, G.420,448 - see Szreniawski, Z. 710, 724 905,909,918,919,920,930 - see Curry, D. L. 421, 445 Gunn, J. A., see Cooper, H. A. Greene, A. L. 503, 527 - see Karam, J. H. 422, 451 868,885 Greengard, O. 368, 375, 448 Groh, R. H., see Jenkins, R. B. - Epstein, D. 858, 886 - see Csanyi, V. 375, 445 865,890 Gunne, L.-M. Il9, 177, 845, 888 Greengard, P., Costa, E. 462 de Groot, J., see Wagner, J. W. - Lidvall, H.-F. 852, 875, 888 - Straub, R. W. 691, 718 488,489,490,537 Gurin, S., Delluva, A. M. 186, - see Den Hertog, A. 691, Groppetti, A., Algeri, S., Bloom, 223 717 F., Costa, E., Revuelta, A. Gustafsson, B., see Strandberg, - see Kuo, J. F. 365, 369, 394, 857,888 K. 165,184 401,452 - see Bloom, F. E. 47, 64,67, Gustafsson, E., see Anden, N. - see Miyamoto, E. 428, 454 72,828,836 E. 197, 198, 206, 219, 737, - see Reik, L. 366, 368, 457 Gross, P. R., see Grand, R. J. 756 Greenough, W. B., Crespin, S. 425,448 Gut, M., see Hagopian, M. Il2, R., Steinberg, D. 422, 448 Grossman, S. P. 471,473,479, 177 - see Crespin, S. R. 422, 445 488,510,527 Gutenstein, M., see Shaw, K. Greer, C. M., Pinkston, J. 0., Gruber, C. M. 796, 797,800,807 N. F. 877, 896 Baxter, J. H., jr., Brannon, Griindig, E., see Bruck, H. 850, Gutman, A., Shafrir, E. 388, E. S. 2, 14 884 448 Author Index 961

Gutman, Y., Weil·Malherbe, H. Haggendal, J., Lindqvist, M. Hakanson, R., Owman, C. 133. 164,177 218,223,497,498,527 177, 816, 838 Gyermek, L. 661, 694, 718 - Malmfors, T. 121, 157, 177, - Owman, C., Sjoberg, N.-O. - Bindler, E. 708, 709, 718 57l, 610, 634, 654 133,177 - Sigg, E. B., Bindler, E. 705, - see Adams-Ray, J. 25, 39 - see Falck, B. 133, 176 718 - see Dahlstrom, A. 121, 126, Hake, T. 48, 74 Gyorgy, L., see Pfeifer, A. K. 157,174,216,221,566,567, Halaris, A., Ruther, E., Matus• 504,533 569, 607, 826, 837 sek, N. 61, 74 - see Dencker, S. J. 120,174 Hales, C. N., see Perry, M. C. Haag, H. W., Philippu, A., - see Falck, B. 114, 115, 140, 382,383,455 Schiimann, H. J. 241, 264, 176 - see Randle, P. J. 402, 456 914,927 - see Folkow, R 216, 223, - see Wade, D. R. 388, 389, Haase, H. J., Janssen, P. A. J. 240,264,566,567,568,569, 461 848,888 609 Haley, T. J., McCormick, W. Haase, M., see Shahab, L. 399, - see Frontali, N. 84, 99, 106 G. 470, 47l, 476, 527 458 Hallstrom, T., Persson, T. 866, Haljasmaa, 0., see Ross, S. B. Habeck, D. A., see Thomson, 888 506,534 J. F. 411, 412, 460 Harkonen, M. 787, 807 Hall, G., see Bertler, A. 241, Haber, R, see Pscheidt, G. R. - Passonneau, J. V., Lowry, 242,262 147,181 O. H. 662, 719 Hall, M. T., see Bowman, W. Haber, J., see Klingman, G. I. - see Eranko, O. 786, 806 C. 297, 298, 330, 792, 795, 165,179 Haeusler, G. 356, 357, 358, 709, 804 Haberland, G., see Kroneberg, 7l2, 7l3, 815 Hallberg, D., see Carlson, L. A. G. 750, 759 - Gerold 831 387,444 Habermann, E. 99, 107 - Haefely,W.,Huerlimann,A. Hallenbeck, G. A., see Stickler, Habighorst, L. V., see Bassler, 690,693,712,713,719,774, G. R 932 R. 909, 911, 924 778,807,814, 831, 834, 838 Halliwell, G., Quinton, R. M., Hack, M. A., see Leimdorfer, -- Thoenen, H. 737, 745, Williams, F. E. 500, 527 A. 470, 47l, 530 758,815,827,828,831,833, Halperin, M. L., Denton, R. M. Haddock, R A., see Garland, 838 388,389,449 P. R 415, 448 --- Huerlimann, A. 777, - see Denton, R. M. 389, 390, Hadley, M. E., Goldman, J. M. 807 445 434,448 - Thoenen, H., Haefely, W. Halpern, R N., Drudi-Barac• - see Goldman, J. M. 448 827,828,838 co, C., Bessirard, D. 496, Haefely, W. 584, 586, 589, 67l, -- Haefely, W.,Hiirlimann, 527 677,680,681,684,687,693, A. 588, 610, 666, 693, 704, Hamada, M., see Ayukawa, S. 695,696,697,698,700,701, 706,712,719,775,776,777, 191,219 702,703,705,706,707,708, 807 Hamberg, D., see Euler, D. S. 709, 710, 712, 718, 719 - see Thoenen, H. 620, 626, V. 18,41, Ill, 170,175, 188, - Hiirlimann, A., Thoenen, H. 633,643,646,648,650,659, 222 199,223,240,264,568,610, 827, 829, 834, 842 Hamberger, B. 500, 527, 621, 623,627,633,637,643,644, Hagen, J. M. 424, 449 622,654 646,647,648,650,651,654, - see Blaschko, H. 5, 12, 249, - Levi-Montalcini, R., Nor• 686,693,695,697,701,709, 262, 539, 574, 606, 906, 924 berg, K. A., Sjoqvist, F. 710, 719, 753, 758, 833, 838 Hagen, P. 4, 14, 902, 927 820, 821, 822, 830, 838 - Staehelin, H., Thoenen, H. - D'Iorio, A. 244, 264 - Malmfors, T., Norberg, K.• 704,708,719 - Welch, A. D. 4, 14 A., Sachs, C. 199, 209, 224, - see Haeusler, G. 588, 610, - see Blaschko, H. 5, 12, 26, 622,654 666,690,693,704,706,712, 31, 40, 232, 248, 249, 255, -- Stjarne, L. 240, 264 7l3, 719, 737, 745, 758, 774, 262, 539, 574, 606, 906, 924 - Norberg, K.-A. 662, 719, 775,776,777,778,807,814, Hagen, P. B., Cohen, L. H. 224 787, 807 815,827,828,831,833,834, - see Burack, W. R. 249, 261, -- Olson, L. 747, 758 838 263, 548, 550, 607 -- Sjoqvist, F. 662, 719 - see Thoenen, H. 160, 167, - see Weiner, N. 548, 550, -- Dngerstedt, U. 662, 719, 184,209,211,212,229,240, 560,617 787,796,807 268,351,356,361,504,536, Hager, C. R, Kenney, F. T. - Ritzen, M., Wersall, J. 23, 588,590,616,620,621,625, 375,376,449 42,922,927 626,627,628,629,632,633, Hagopian, M., Dorfman, R. I., - see Anden, N.-E. 149, 171 643,646,648,649,659,712, Gut, M. 112, 177 - see Brundin, T. 124,173 724,767,778,779,812,814, Hahn, P., see Drahota, Z. 412, - see Carlsson, A. 499, 522 823, 826, 827, 842, 875, 897 446 - see Fuxe, K. 499, 525 Haeger, K., see Folkow, B. 762, Hajdu, S., Weiss, H., Titus, E. - see Jonsson, G. 203, 225 806 592,610 - see Norberg, K.-A. 216, 227, Haggendal, J. 112, 128, 131, Hakanson, R., Lilya, R, Ow• 240, 266, 662, 723, 787, 811 177,507,527 man, C. 133, 165, 177 - see Wirsen, C. 130, 185 61 Hdb. expo Pharmakol., Vol. XXXIII 962 Author Index

Hamberger, C. A., Hamberger, Hanson, L. C. F. 501, 502, 527 Hartman, W. J., Akawie, R. I., C. B., Wersiill, J., Wager• - see Corrodi, H. 501,502,523 Clark, W. G. 191, 224, 853, mark, J. 922, 927 Hanstrom, B. 85, 107 867,880,889 Hamberger, C. B., see Ham• Hanze, A. R., see Moffett, R. B. - Clark, W. G., Cyr, S. D., berger, C. A. 922, 927 506,532 Jordan, A. L., Leibhold, R. Hamburger, V., see Levi-Mon• Hara, T., see Ayukawa, S. 191, A. 92, 107 talcini, R. 818, 840 219 - Pogrund, R. S., Drell, W., Hamer, J., see Hess, M. L. 398, Harakal, C., see Shindler, R Clark, W. G. 188,224 449 160,183 Hartmann, W. H., see Schimke, - see Shinebourne, E. A. 398, Haranath, P. S. R. K., Prema• R. N. 901, 931 459 latha, K., Rao, N. R. 911, Harvey, J. A., see de la Lande, Hamilton, C. L., see Spector, 927 I. S. 111,179 N. H. 491, 536 - see Dra81roci, M. 464, 478, Harvey, S. C., Nickerson, M. Hamilton, D. N. H., see Gille• 524 479,509,527 spie, J. S. 747, 748, 758 Harbich, I., see Hertting, G. Harwood, J. P., see Drum· Hamilton, T. C. 351, 358 735,736,737,758,834,838 mond, G. I. 401, 402, 446 Hamlin, J. R, see Friend, G. Hardman, H. F., see Meester, Hasenbush, L. L., see Klerman, 271,280 W. D. 399, 454 G. L. 862, 890 Hammermeister, K. E., see Hardman, J. G., Mayer, S. E., Hashimoto, Y., Ishii, S., Ohi, Posner, J. B. 404, 456 Clark, B. 737, 758 Y., Imaizumi, R 61, 74 Hammond, W. G., see Engel• Hardy, J., see Papeschi, R 859, Hasner, E. H., see Laursen, T. man, K. 902, 912, 925 893 912,928 - see Sjoerdsma, A. 912, 931 Hare, M. L. C. 5, 14, 271, 280 Hasselbach, W., Seraydarian, Hancock, C., Kosersky, D. S., Hare, T. A., see Vogel, W. H. K. 245, 264 Volle, R. L. 705, 719 853, 854, 867, 868, 898 - see Taugner, G. 205, 229, - Volle, R. L. 686, 697, 703, Hargrove, M. D., jr., see An• 242,243,244,245,246,250, 719 lyan, W. G. 861, 881 253,257,258,268,539,616 Handelman, C., see Wells, H. Harlan, W. R., jr., see Goodall, Hassler, R. 857, 889 425,461 McC. 855, 888 - Riechert, T. 847, 889 Handler, J. S., Bensinger, R., Harman, S. M., see Rubin, R. Hassler, R J., see Grobecker, Orloff, J. 433, 434, 449 P. 124,182 H. 587, 590, 610 - Butcher, R. W., Sutherland, Harper, A. M., see Hanington, Haugaard, E. S., see Haugaard, E. W., Orloff, J. 433, 449 E. 850, 889 N. 397, 449 Handley, S. L., see Brittain, Harris, B., see Luse, S. A. 466, Haugaard, N., Haugaard, E. S., R. T. 470, 471, 481, 507, 530 Lee, N. H., Horn, R S. 397, 509,521 Harris, S. C., see Ivy, A. C. 471, 449 Hanieh, A., see Guldberg, H. C. 528 - Hess, M. E. 391, 395, 449 859,888 Harris, W. S., Schoenfeld,C.D., - see Hess, M. E. 391, 399, - see Pullar, I. A. 859, 872, Brooks, R H., Weissler, A. 449 873,894 M. 491, 527 Havel, R. J. 491, 527 Hanig, J. F., Morrison, J. M., Harrison, D. C., Chidsey, C. A., - Carlson, L. A., Ekelund, L .. jr., Krop, S. 873, 888 Goldman, R, Braunwald, G., Holmgren, A. 491, 527 Hanington, E. 850, 889 E. 355, 358 - Naimark, A., Borchgrevink, - Harper, A. M. 850, 889 - see Chidsey, C. A. 355, 358, C. F. 404, 449 - see Sandler, M. 850, 895 468, 522, 629, 653 - Pernow, B., Jones, N. L. - see Smith, I. 850, 896 Harrison, E. G., see Fuller, A. 404,449 - see Youdim, M. B. H. 850, M.923,926 Haverback, B. J., Dyce, B., 899 - see Levit, S. A. 929 Thomas, H. V. 851, 889 Hanlon, C. R, see Cooper, T. Harrison, H., see Mahoney, E. HavliCek, V. 497, 506,527 815,837 M.912,929 Hawes, R., see Bergeret, B. 7, Hanly, C., see Awapara, J. 188, Harrison, T. S. 467, 527 12 219 - Barlett, J. D., Seaton, J. F. Hawkins, D. F., see Fleming, Hannon, J. P., Evonuk, E., 915,927 W. W.314,331 Larson, A. M. 485, 527 - Seaton, J. F. 132, 177 Hawkins, J., see Bueding, E. Hano, K., see Iwata, H. 167, -- Cerny, J. C., Bookstein, 405,406,444 178 J. J., Bartlett, J. D. 912, Hayden, M. L., see Davey, M. Hansen, S., see Perry, T. L. 927 J. 704, 713, 716,776,805 851,893 Harrison, V., see Blakeley, A. Haydon, D. A., Taylor, J. 593, Hanson, A., von Studnitz, W. G. H. 568, 606 610 875, 889, 921, 927 Harrison, W. H., see Scheving, Haynes, R. C., jr., see Adam, - see Studnitz, W. v. 921, 932 L. E. 119, 182 P. A. J. 372, 377, 441 Hanson, E., see Masuoka, D. T. Hart, J. S., see Jansky, L. 408, Hayward, J. S., Ball, E. G. 411, 626,656 411,417,450 417,449 Hanson, H. M., see Torchiana, Hart·Mercer, J., see Mason, G. Hazelrig, C. G., see Zimon, R M. L. 628,651,659 A. 917, 920, 929 P. 912, 933 Author Index 963

Heacock, R A. 49, 74 Heise, G. A., see Boff, E. 496, Henning,M.192,224,236,264, Head, R., see Slarotinek, A. 521 652,654,864,889 901,932 Heise, R., see Holtz, P. 2, 14, - Rubenson, A. 864, 889 Head, R J., see de la Lande, 1. 187,224, 619, 654, 848, 852, - Svensson, L. 646, 651, 654 S.169,179 864,889 - see Andlm, N.-E. 157, 171, Heath, 1. D., see Coupland, R. Helle, K. B. 250, 264, 542, 556, 236,261,641,642,652 E. 25, 40 610 Henry, R. J., see Jacobs, L. S. Heaton, D. G., see Esplin, D. - Serck-Hansen, G. 250,264, 912,928 W.517,524 592,610 Henson, G., see Coulson, W. F. Hebb, C., Kasa, P., Mann, S. - see Banks, P. 5,12,34,39, 877,885 125,177 68, 72, 217, 220, 250, 262, Hepp, D., Challoner, D. R, Hebb, C. 0., Konzett, H. 737, 555,556,557,605 Williams, R. H. 389, 449 758 - see Blaschko, H. 250, 262 - Menahan, L. A., Wieland, Hechter, 0., see Bar, H. P. 368, Heller, A., see Brownstein, M. 0.382,449 382,384,386,442 J.432,444 Hepp, D. K., see Williams, R. - see Dousa, T. 433, 446 Hellerman, L., see Erwin, V. G. H. 382, 462 Hedges, A., Turner, P. 323, 325, 7,13 Herczeg, B., see Williamson, J. 332 Hellerstein, D. 586,610 R. 373, 374, 462 Hedqvist, P. 214, 224 Hellman, B., see Cegrell, L. Herd, P. A., Horwitz, B. A. - Stjarne, L. 240, 264, 568, 129,173 412,449 610 - see Falck, B. 129, 176 - see Horwitz, B. A. 413, 450 - see Euler, U. S. von 711, Hellman, G., see Peskar, B. Herman, E. H., Barnes, C. D. 717 201,204,227 517,528 - see Stjarne, L. 217,229,240, Hellmann, K. 764, 807 Hermann, H., Mornex, R. 900, 249,268,568,569,574,616 - see Gardiner, J. E. 767, 901,902,903,904,913,927 Hedwall, P. R., see Brunner, H. 806 Hellner, S., see Euler, U. S. von - Mornex, R. 861, 889 637,646,647,648,652 132,170,175,188,222 Hern, E. P., see Glinsmann, W. Heffler, S., see Baserga, R 425, Hellner-Bjorkman, S., see Eu• H. 370,371, 375, 448 426,442 ler, U. S. von 194, 197, 222 Hernandez, R. E., see Gagliar• Heffron, P. F., see Green, J. H. Hellon, R. F., see Feldberg, W. dino, J. J. 421, 447 664, 718 483,484,524 Hernandez-Peon, R., Chavez• Hegnauer, A., Cori, G. T. 10, Ibarra, G., Morgane, P. J., 14 Hellstrom, J., see Euler, U. S. Timo-Iaria, C. 489, 527 Hehman, K. N., Vonderahe, A. v.270,275,280, 903, 925 Herrera, M. G., see Renold, A. R, Peters, J. J. 464, 527 Helmreich, E. 401, 449 E. 390, 457 Hehn, von G., see Bargmann, - see Danforth, W. H. 401, Herrlich, P., Sekeris, C. E. 913, W.416,442 402,403,405,445 921,927 Heidenberg, W. J., see Thurm, Hemingway, A., Forgrave, P., - see Sekeris, C. E. 875, 895, R H. 914, 933 Birzis, L. 494, 528 913,931 Heidenreich, 0., see Fiilgraff, - see Stuart, D. G. 494, 536 Herrnstein, R. J., see Morse, G. 319, 331 Hempel, K., MannI, H. F. K. W. H. 480, 532 Heidingsfelder, S. A., see Black• 123,177,233,257,264,565, Herron, G. R., see Thurm, R. ard, W. G. 435, 443 610 H. 914, 933 Heier, G., see Wollenberger, A. Hems, R., see Ross, B. D. 374, Hers, H. G., see De Wulf, H. 399,462 458 369,370,446 Heilbriinn, L. V. 602, 610 Henderson, A. H., Most, A. S., Hersey, R. M., see Morgan, J. Heilmeyer, L., see Kahler, H. Sonnenblick, E. H. 398, 449 P. 871, 874, 876, 892 J.853,890 Henderson, A. M., see Sokal, J. Hertelendy, F., Machlin, L. J., Heim, F., see Mitznegg, P. 406, E. 367, 371, 459 Gordon, R. S., Horino, M., 454 Henderson, J. R., see Daniel, Kipnis, D. M. 422, 449 Heim, 1., Hull, D. 408, 411, P. M. 422, 445 - see Horino, M. 422, 450 449 Hendley, E. D., see Snyder, S. Hertting, G. 197,209,224,339, Heimberg, M., Fizette, N. B. H. 500, 535 350,359,737,758,813,815, 367,375,449 Hendry, W. S., see Robertson, 834,838 - Weinstein, 1., Kohout, M. D. M. 920, 930 - Axelrod, J. 202, 224, 274, 373,374,375,449 Heneague, P., see Sourkes, T. 280 - see Van Harken, D. R. 373, 15 -- Kopin, 1. J., Whitby, L. 374,460 Heninger, G., see Van Woert, G. 198,208, 209, 212, 213, - see Wilcox, H. G. 372, 461 M. H. 862, 865,866, 898 224, 813, 816, 833, 838 Heinbecker, P. 690, 719 Heninger, G. R., see Bowers, M. -- Patrick, R. W. 355, 359, - Bishop, G. H. 690, 719 B., jr. 846, 860, 862, 884 814,838 - see Bishop, G. H. 688, 690, Hennemann, H.-M., Trende• -- Whitby, L. G. 500, 528, 715 lenburg, U. 816, 838 814,827,833,838 Heintze, K., see Fiilgraff, G. Henning, H. V., see Seubert, - Potter, L. T., Axelrod, J. 319,331 W. 373, 458 202,224,630,654 964 Author Index

Hertting, G., Schiefthaler, T. Highman, B., see Shore, P. A. Himwich, W. A., Petersen, J. 125,160,177,212,224,813, 159, 169, 183 C., Allen, M. L. 465, 528 815,816,838 Hill, D., see Wada, J. A. 470, - see Agrawal, H. C. 118,171 - Suko, J., Widhalm, S., Har• 479,514,537 Himwich, H. E., see Costa, E. bich, 1. 735, 736, 737, 758, Hill, J. A., see Miller, R. W. 496,523 834,838 917,929 - see Pscheidt, G. R. 118, 154, - Widhalm, S. 767, 775, 807 Hillarp, N.-A. 26, 42, 79, 80, 181,504,505,533,534 - see Axelrod, J. 338, 357, 86, 87, 88, 89, 93, 99, 102, Hintersberger, H., Bartholo• 500, 505, 519, 827, 836 103,236,241,242,244,246, mew, J. R. 905, 918, 920, - see Kopin, 1. J. 278, 281 248,249,250,251,252,253, 921,927 - see Linet, O. 144, 147, 179 255,257,258,264,539,540, Hippius, H., Logemann, G. 861, - see Peskar, B. 201, 204, 227 541,542,548,550,553,556, 889 - see Pichler, H. 8, 14 610,814,838 Hirano, T., see Kobayashi, H. - see Suko, J. 8, 15 - Falck, B. 539, 610 67,75 - see Whitby, L. G. 211, 230 - Fuxe, K., Dahlstrom, A. Hiroshi, H., see Fujiwara, M. Hertzler, E. C. 708, 719 207,224,463,528 129,166,176 Herztman, E., see Drummond, - Hokfelt, B. 23, 42, 122, 130, Hirsch, C. W., see Brodie, B. B. G. I. 392,393,395,446 177 192,220,497,521 Heslop, T. S., see Maycock, W. -- Nilson, B. 246, 257, 265 - see Kuntzman, R. 192, 225, D'A. 34, 43 - Lagerstedt, S., Nilson, B. 5, 505,529 Hess, A., see Zapata, P. 52, 70, 14,248,265,539,610 Hirsch, J. G. 7, 14, 594, 611 78 - Lindqvist, M., Vendsalu, A. Hirschmann, J., Mayer, K. 869, Hess, M. E., Haugaard, N. 391, 904,907,927 889 449 - Malmfors, T. 240,265 Hittelman, K. J., Fairhurst, A. - Shanfeld, J., Haugaard, N. - Nilson, B. 251, 252, 265, 539, S., Smith, R. E. 414, 450 399,449 592, 594, 610 - Lindberg, 0., Cannon, B. - see Frazer, A. 399, 447 -- Hogberg, B. 249, 265, 412,415,450 - see Haugaard, N. 391, 395, 539,610 Ho, R. J., Jeanrenaud, B. 383, 449 - Thieme, G. 541, 550, 610 450 - see Shanfeld, J. 392, 395, - see Adams-Ray, J. 133,171 -- Posternak, Th., Renold, 458 - see Anden, N.-E. 847, 881 A. E. 382, 383, 450 Hess, M. L., Briggs, F. N., - see Bertler, A. 123, 125, 128, -- Renold, A. E. 382, 450 Shinebourne, E., Hamer, J. 131, 160, 161, 165, 166, 167, - see Butcher, R. W. 381, 444 398,449 170,172,236,237,241,242, Hodgkin, A. L. 669, 719 - see Shinebourne, E. A. 398, 262 - Keynes, R. D. 611 459 - see Carlsson, A. 204, 211, Hodgson, B.J., see Daniel,E.E. Hess, S. M., Connamacher, R. 213,221,236,242,243,244, 319,331,406,407,440,445 H., Ozaki, M., Udenfriend, 245,246,249,251,253,259, Hogberg, B., see Falck, B. 249, S. 497, 528, 636, 639, 654 263,337,352,357,495,504, 250, 251, 264, 539, 609 - Redfield, B. G., Udenfriend, 506,522,542,545,546,548, - see Hillarp, N.-A. 249, 265, S.224 550,551,553,556,558,560, 539,610 - see Paulsen, E. C. 149, 181, 607, 621, 622, 644, 653 Hoglund, R. 23, 42 196,227 - see Caspersson, T. 17, 40 Hohn, D., see Trendelenburg, Hestrin, M., see Perry, T. L. - see Von Euler, U. S. 5, 13, U.342, 361, 751, 752, 754, 851,893 50,74,214,222,542,609 761 Hetey, S., see Patil, P. N. 315, - see Falck, B. 5, 13, 17,23, Hoehn, M. M., see Yahr, M. D. 334 41, 125, 127, 176, 188, 190, 861,867,899 Heyd, G., see Philippu, A. 588, 197,199,222,246,249,250, Hokfelt, B., McLean, J. 122, 614 251,257,264,539,609,621, 177, 233, 234, 265 Heymans, C., see De Schaep• 815,837 - see Anden, N.-E. 641, 652 dryver, A. F. 132, 161, 166, - see Fuxe, K. 499, 525 - see Bygdeman, S. 233, 234, 182 Hillman, C. C., see Allen, D. O. 263 - see Nagasaka, M. 298, 333 301,302,330,387,441 - see Carlsson, A. 249, 263, Heynen, H. P., see Schmid, E. Hilton, J. G., Steinberg, M. 499,500,502,503,504,522, 914, 931 684, 719 545,548,550,551,553,556, Hidaka, H., see Nagatsu, T. - see Athos, W. J., 915, 924 560,607 557,613 - see Scian, L. F. 915, 931 - see Fuxe, E. 37, 41, 46, 61, Hidaka, T. 99, 107 Himms-Hagen, J. 11, 294, 301, 67,71,74,467,525,866,887 - Kuriyama, H. 802, 808 319,332,366,371,379,384, - see Hillarp, N.-A. 23, 42, Hiebel, G., see Bonvallet, M. 385,386,387,390,395,401, 122, 130, 177, 246, 257, 265 477,521 404,406,408,409,410,411, H6kfelt, T. 46, 47, 48, 50, 52, Higgins, J. A., see Reik, L. 366, 412,417,437,440,449,491, 53, 54, 56, 58, 60, 61, 63, 64, 368,457 528 67,68,71,75,159,166,167, Highman, B., see Maling, H. M. - see Bonin 418 177,214,224,232,233,234, 272,281,505,530 - see Muirhead, M. 408, 455 265, 566, 602, 611, 778, 808 .Author Index 965

Hokfelt, T., Jonsson, G. 47,48, Holman, M. E., see Merrillees, Honos, E., Ericsson, .A. D., 56, 58, 63, 75 N. C. R. 729, 731, 760 McCann, D. S. 876, 889 - Ungerstedt, U. 47, 64, 71, - see Szurszewski, J. H. 677, Honour, .A. J., see Cooper, K. 75 724 E. 482, 523 - see .Anden, N.-E. 149, 171 Holmes, D., see Goffart, M. 708, Honova, E., see Drahota, Z. - see Corrodi, H. 200, 202, 718 412,446 221,502,523 Holmes, O. 686, 719 Hope, D. B. 921, 927 - see Dahlstrom, .A. 121, 126, - see Brown, G. L. 686, 691, - see Blaschko, H. 96, 102, 157,174,216,221,566,567, 694,716 105 569,607 Holmes, R. L., see Coupland, Hopsu, V. K., Makinnen, E. O. Hortnagl, H. 604 R. E. 34, 40 48,75 - Hortnagl, H., Winkler, H. Holmgren, .A., see Havel, R. J. - see Arstila, .A. W. 52, 72 214,224 491,527 - see Paikama, .A. 24, 43 - SchOpf, J., Winkler, H. 600 Holstein, .A.-F., see Baumgar• Hopwood, D. 26, 27, 42 - see Hortnagl, H. 214, 224 ten, H. G. 126, 144, 163, - see Coupland, R. E. 17, 25, - see Plattner, H. 563, 614 172,796,803 26,41,48,49,50,73 - see Winkler, H. 539, 540, Hoisti, L. R. 913, 927 Horak, B. J. V., see Graeff, J. 555,558,559,592,600,617 Holt, D . .A., see Bradham, L. S. de 901, 926 Hoffman, H., Birrell, J. H. W. 382,427,443 Horino, M., Machlin, L. J., Her• 23,24,42 Holt,P.G., Oliver, I. T. 375, 450 telendy, F., Kipnis, D. M. Hoffman, M., see Senft, G. 367, Holten, D., Kenney, F. T. 376, 422,450 458 450 - see Hertelendy, F. 422, 449 Hoffmann, E. J., see Hoffmann, Holton, P. 122,177,904,927 Horita, .A. 354, 359 F. 764, 808 - Rand, M.J. 763, 808 - see Eltherington, L. G. 505, Hoffmann, F., Hoffmann, E. J., - see Blaschko, H. 188, 220, 524 Middleton, S., Talesnik, J. 878,883 Horlington, M., see Davis, R . .A. 764,808 Holtz, P. 2,117,177,187,188, 192,221 Hofmann, W. W., Ryan, R. L. 192,224,864,868,889 - see Drain, D. J. 497, 524 860,889 - Credner, K. 132, 177, 189, Horn, .A. S., Coyle, J. T., Sny• Hohorst, H.-J., Rafael, J. 412, 224 der, S. H. 870, 889 450 -- Koepp,W.188,224,852, Horn, N., see Kerkut, G. .A. 8, - see Rafael, J. 412, 415, 456 875,889 96,97,107 Hokin, L. E. 594, 596, 611 -- Kroneberg, G. 132, 177 Horn, R. C., see Koop, C. E. - see Hokin, M. R. 594, 611 -- Walter, H. 188,224 917,928 Hokin, M. R., Benfy, B. G., - Heise, R., Ludtke, K. 2, 14, Horn, R. S., see Haugaard, N. Hokin, L. E. 594, 611 187,224,619,654,848,852, 397,449 - Hokin, L. E., Shelp, W. D. 864,889 Hornbrook, K. R. 294, 319, 611 - Kroneberg, G., Schuman, 332, 376, 440, 450 Holbach, K. H., see Bettag, W. H.-J. 132,177 Horne, R. W., see Bangham, A. 862,883 - Osswald, W., Stock, K. 337, D. 593, 605 Holgerson, L. 0., see .Anderson, 359 E. G. 119, 154, 171 - Palm, D. 2, 14, 188, 224, Hornykiewicz, O. 188, 225, 275, Holland, W. C., Schumann, H. 252,258,261,265,353,359, 281,497,528,845,854,855, J.233,234,265 639,647,652,654,860,864, 856,857,872,873,889 - see .Auditore, G. V. 376, 442 867, 868, 889, 900, 927 - see Aigner, A. 504, 518 Hollander, P. B., see Walsh, M. - Stock, K., Westermann, E. - see Barolin, G. S. 856, 860, J.353,362 864,889 882 Hollands, B. C. S., Vanov, S. - Westermann, E. 188, 224, - see Bernheimer, H. 848, 730,758,787,808 867,889 854,856,858,859,868,879, Hollenberg, N. K., see Nicker• - see Balzer, H. 742, 752, 756 882,883 son, M.507, 511, 533 - see Fein, J. 647, 653 - see Birkmayer, W. 4, 12, Hollett, C. R., .Auditore, J. V. - see Grobecker, H. 115, 140, 188, 220, 846, 860, 861, 868, 388,450 177,341,358,587,590,610, 870, 879, 880, 883 Holloway, C., see Kirshner, N. 619, 628, 637, 654 - see Born, G. V. R. 132, 172 236,244,246,249,250,251, - see Palm, D. 297, 334, 648, - see Ehringer, R. H. 4, 13, 258,265 657 111,155,174,190,222,846, Holman, M. E. 565,566,611, Holtzman, E., Dominitz, R. 68, 848,856,886 731,758 75,597,598,599,600,601, - see Holzer, G. 868,889 - Crowcroft; P. J., Ostberg, 611 - see Lisch, H.-J. 148,179 A., Szurszewski, J. H. 719 Holzbauer, M. 538, 611 - see Lloyd, K. 854, 867, 868, - see Blackman, J. G. 664, - Sharman, D. F. 854 891 668,674,677,688,715 - Vogt,M.5, 14,131,178,244, Horowitz, J. M., jr., see Hor• - see Burnstock, G. 693, 716, 265,814,839 witz, B. .A. 409, 450 763,805 Holzer, G., Hornykiewicz, O. Horridge, G. .A., see Bullock, T. - see Crowcroft, P. J. 688, 716 868,889 H. 86, 87,105 966 Author Index

Horst, W. D., see Fischer, J. E. Hubert, J. W. A., van Rossum, Hunter, K. R., see Bonham 621,626,631,632,633,642, J. G. 846, 889 Carter, S. 851, 883 653 Hudgens, R. W., see Robins, E. - see Fleming, P. 861, 862, - see Kopin, I. J. 205, 208, 854,894 887 225,274,275,281,338,352, Huebl, H., see Furchgott, R F. Hunter, R B., Marshall, P. B., 359,502,529,619,621,626, 271, 280, 742, 752, 757 Oram,F.J.22,42,902,927 629,633,642,646,655,816, Hiirlimann, A., see Haefely, W. - see West, G. B. 22, 44,123, 839 199,223,240,264,568,610, 185 - see Wurtman, R J. 198, 623,627,633,637,643,644, Hunter, W. H., see Farrugia, 230,274,282,816,844 646,647,650,651,654,686, M. T. 624, 653 Horton, E. W., see Davies, B. 693,695,697,701,709,710, Hurkmans, J. A. T. M., see ~. 618, 653,711, 716 719, 753, 758, 833, 838 Rossum, J. M. van 623,624, Horwitz, B. A., Herd, P. A., - see Haeusler, G. 588, 610, 658 Smith, R E. 413, 450 666,690,693,704,706,712 Huston, R B., Krebs, E. G. - Horowitz, J. M., jr., Smith, 713 719,774,775,776,777, 403,450 R. 409, 450 778, 807, 814, 831, 834, 838 Hutchinson, R. R., Renfrew, J. - Smith, R E., Pengelley, E. - see Thoenen, H. 160, 167, W. 488, 528 T. 417, 450 184,209,211,212,229,240, Hutter, O. F., Lowenstein, W. - see Herd, P. A. 412, 449 268,351,356,361,504,536, R 800, 801, 808 - see Imai, Y. 417, 450 588,590,616,620,621,625, Hynie, S., see Wenke, M. 291, - see Smith, R E. 408, 416, 626,627,628,629,632,633, 312,335 417,418,459 643,646,648,649,650,659, Hyyppa, M., Rinne, U. K., Horwitz, D., Goldberg, L. I., 767,778,779,812,814,823, Sonninen, V. 866, 890 Sjoerdsma, A. 863, 869, 889 826, 827, 842, 875, 897 - Lovenberg, W., Engelman, Hug, C. C., jr., see Weisbrodt, Ibarra., J., see Albores-Saave• K., Sjoerdsma, A. 850, 889 ~. W. 327, 335 dra, J. 909, 924 - see Engelman, K. 914, 925 Hughes, J., Gillens, C. ~., Ichikawa, Y., Yamano, T. 248, - see Pettinger, W. A. 619, Bloom, F. E. 203, 225 265 657 - see Boadle, M. C. 195,220 Igna.rro, L. J., Shideman, F. E. Hosie, R J. A., see Gillespie, J. Hughes, R. C., Polgar, J. G., 117,143,178 S.748,758 Weightman, D., Walton, J. - Titus, E. 298, 323, 327, 332 Hosoi, K., see Ozawa, E. 403, ~. 865, 866, 869, 889 Ikeda, M., Fahien, L. A., Uden• 455 Hughes, S. D., see Jost, J.-P. friend, S. 194, 196, 225 Hoszowska-Owczarek, A., Lan• 375,450 - Levitt, M., Udenfriend, S. ger, S. Z., Djordjevic, ~., Huijing, F., Lamer, J. 393, 450 187,225,234,265,619,655 de Schaepdryver, A. F _353, - see Lamer, J. 404, 452 - see Imura, H. 435, 450 359 Hukovi6, S. 762, 767, 774, 808 Ilves-Haggendal, M., see Denk• Hottenstein, M_, see ~ichols, C. - Muscholl, E. 211, 212, 225, ker, S. J. 120, 174 W. 121, 157,181 240,265,586,588,611,649, Imai, Y., Horwitz, B.A.,Smith, House, E. C., see ~akano, J. 654,753,758,774,781,808, R E. 417, 450 385,455 814, 839 - see Smith, R E. 417, 459 Houssay, B. A., Gerschman, R., Hull, D., Segall, M. M. 417, 450 Imaizumi, R., see Hashimoto, Rapela, C. E. 140, 178 - see Dawkins, M. J. R 485, Y. 61, 74 - Wassermann, G. F., Tramez• 491,523 - see Ishii S. 61, 75 zani, J. H. 20, 42, 142, 178 - see Heim, I. 408, 411, 449 - see Matsuoka, M. 61, 76, Howell, J. I., Lucy, J. A. 593, Hume, D. M. 900, 901, 927 118, 148, 180, 507, 531 611 Hume, W. R., see Waterson, J. - see ~ukada, T. 504, 533 Howell, S. L., see Edwards, J. G. 780, 812 - see Oka, M. 239, 246, 248, C. 422, 446 Humphreys, R J., see Raab, 254,255,256,259,266,267, - see Lacy, P. E. 420, 421, 452 W. 816, 841 539,542,559,587,591,595, Hrfiza, Z., Albrecht, I., Jelin• Hunt, C. C., ~elson, P. G. 664, 596,614 kova, M., Erdosova, R. 170, 668, 675, 689, 720 Imashuku, S., La Brosse, E. H. 178 - Riker, W. K. 664 667,668, 917,927 Hsie, A., see Jost, J.-P. 375, 670,671,689,720 Imura, H., Kato, Y., Ikeda, M., 450 Hunt, J. M., see Fuller, R W. Morimoto, M., Yawata, M., Hsieh, A. C. L., Carlson, L. D. 231,264 Fukase, M. 435, 450 491,528 Hunter, K. R., Boakes, A. J., Ingold, C. K., see Cahn, R. S. Huang, S. ~., McLeish, W. A. Laurence, D. R, Stern, G. 623,652 901,909,927 M. 863, 869, 889 Ingram, D. L., see Baldwin, B. Hubbard, J. I., Schmidt, R. F. - Stern, G. M. 880, 889 A.171 692, 720, 789, 802, 808 -- Laurence, D. R. 863, Ingvarsson, C. G. 862, 890 - Willis, W. D. 802, 808 867,869,890 Ingvarsson, G. 862, 890 - see Gage, P. W. 694, 718 --- Armitage, P. 869, Innes, I. R., Kohli, J. D. 341, Hubbard, S. J. 689, 720 870,890 359 Huber, G. C. 690, 720 -- Sharkey,J. 861, 890 - 356,359 Author Index 967

Innes, I. R., KosterIitz, H. W. Iversen, L. L., see Eisenfeld, Jiirlfors, U., Smith, D. S. 603, 737, 758, 833,839 A. J. 278, 280 611 Inoue, M., Akimoto, H. 140, - see Evetts, K. D. 865, 886 Jaim-Etcheverry, G., Zieher, L. 178 - see Fischer 468 M.46,48,56,58,63,75, 126, Iorio, L. C., McIsaac, R. J. 709, - see Glowinski, J. 118, 149, 161, 178, 901, 928 720 176,193,223,236,264,466, - see Pellegrino de Iraldi, A. - see Moore, P. F. 406, 454 467,468,495,497,498,499, 60,61,76 Ireson, J. D., see Salmon, G. K. 500,504,505,526 Jalfre, M., see Burkard, W. P. 651,658 - see Jarrot 349 828,829,836 Ishida, N., see Itoh, C. 123,178, - see Lightman, S. 278, 281, JaIife, J., see Kabela, E. 318, 232,265,906,912,928 569,613,747,748,750,759 332 - see Sato, T. 905, 912, 931 - see Uretsky, N. J. 64, 78, Jalon, P. G. De, Bayo, J. B., Ishida, T., see Burton, S. D. 828, 829, 831, 843 DeJalon, M. G. 111,178 376,444 Iversen, S. D., see Evetts, K. D. James, W. O. 112, 178 Ishii, S. 61, 75 865,886 Jameson, H. D. 865, 867, 890 - Shimizu, N., Matsuoka, M., Ivy, A. C., Goetzl, F. R.,Harris, Jamieson, J. D., Palade, G. E. Imaizumi, R. 61, 75 S. C., Burrill, D. Y. 471, 528 598,611 - see Hashimoto, Y. 61, 74 Iwanow, G. 783, 808 Janakidevi, K., Dewey, V. C., - see Matsuoka, M. 61, 76 Iwata, H., Fujimoto, S., Nishi• Kidder, G. W. 81, 85, 107 - see Shimizu, U. 61, 77 kawa, T. Hano, K. 167,178 Jang, C.-S. 313, 332 Ishii, T., see Nakano, J. 385, Izquierdo, J. A., Jofre, I. J., Jankowska, E., Jukes, M. G. 455 Dezza, M. 507, 528 M., Lund, S., Lundberg, A. Issekutz, B., jr., Miller, H. I., - Kaumann, A. J. 750, 758 518,528 Rodahl, K. 404, 450 - Merlo, A. B. 507, 528 - Lund, S., Lundberg, A. 518, Ito, H., see Arakawa, T. 852, - see Jofre, I. J. 136, 178 528 881 - see Merlo, A. B. 507, 531, Janssen, P. A. J., see Haase, H. Ito, M., Oshima, T. 672, 673, 532 J.848,888 720 Jansky, L. 411, 450 Itoh, C., Yoshinaga, K., Sato, Jaanus, S. D., Miele, E., Rubin, - Hart,J.S.408,411,417,450 T., Ishida, N., Wada, Y. R. P. 589, 611 Jaques, P., see Beaufay, H. 123, 178, 232, 265, 906, 912, - see Rubin, R. P. 549, 586, 249,262 928 587,615,914,930 Jaramillo, J., Volle, R. L. 686, - see Sato, T. 905, 912, 931 Jackman, L. M., see McCarl, R. 695,697,701,703,704,705, Itoh, S., see Kuroshima, A. 408, L. 398, 454 706,708,720 411,452 Jackson, C. J., see Musacchio, Jard, S., see Bastide, F. 434, Iturriza, F. C. 116, 178 J. M. 337,360, 635, 656 442 - see Enemar, A. 116, 175 Jackson, C. M. 30, 42 Jardetzky, P., see Weiner, N. Iversen, L. L. 50, 75, 197, 203, Jacobi, C., Roemer, C. 482, 528 250,269 204,225,281,302,303,307, Jacobowitz, D. 125, 178, 796, Jarett, L., see Cryer, P. E. 382, 332,349,350,352,359,468, 808 445 500,528,622,655,736,739, - Woodward, J. K. 662, 720, J arrot, B. 746, 759 744,746,747,748,749,750, 787,808 - Iversen, L. L. 349 758,814,815,821,822,831, - see Laties, A. M. 121, 179 - Langer, S. Z. 752, 759 839 - see Nichols, C. W. 121, 157, - see Iversen, L. L. 157, 163, - Axelrod, J., Glowinski, J. 181 166,178, 813, 816, 822, 839 208,212,225 - see Patil, P. N. 347, 351, Jasmin, G., see Barbeau, A. - De Champlain, J., Glowin• 360, 621, 657 880,882 ski, J., Axelrod, J. 198,211, Jacobs, L. S., Sobel, C., Henry, Jasper, H. H., Bridgman, C. S., 225 R. J. 912, 928 Carmichael, L. 476, 528 - Glowinski, J. 467, 468, 469, Jacobsen, C. F., Kennard, M. Javid, R., see Frohman, L. A. 528 A. 516, 528 422,447 -- Axelrod, J. 209, 212, Jacobson, J., see Ursillo, R. C. Jeanrenaud,B.379,389,450 218,225,278,281,570,611, 731,761 - see Ho, R. J. 382, 383, 450 621, 622, 655, 813, 814, 816, Jacoby, G. A., see Page, L. B. - see Lambert, A. E. 420, 421, 820, 821, 822, 828, 830, 831, 905,906,909, 913, 918, 919, 452 834,839 921,930 - see Letarte, J. 382, 383, 453 - Jarrott, B. 157, 163, 166,178 Jacquot, C., Bralet, J., Cohen, - see Touabi, M. 383, 390, 460 -- Langer, S. Z. 813, 816, Y., Valette, G. 351, 359 Jefferson, L. S., Exton, J. H., 822,839 Jaeger, C. P. 94 Butcher, R. W., Suther• - Kravitz, E. A. 204, 225 - Jaeger, E. C., Welsh, J. H. land, E. W., Park, C. R. - Langer, S. Z. 749, 758 94,107 368,370,450 - Salt, P. J. 749, 758 Jaeger, E. C., see Jaeger, C. P. Jefferson, L. S., jr., see Exton, - see Bloom, F. E. 5, 12 94,107 J. H.371,374,447 - see Burgen, A. S. V. 207, Jaenig, W., Schmidt, R. F. 688, Jellett, L. B., see De la Lande, 220,649,652 720 I. S. 742, 743, 757 968 Author Index

Jellinek, M., see Cooper, T. 815, Johnston, J. P. 6, 14, 869, 890 Jungas, R. L., Ball, E. G. 381, 837 Johnston, V. S., see Smythies, 451 - see Musacchia, X. J. 142, J. R. 866, 897 Junod, A., see Lambert, A. E. 180 Joly, J. G., see Barbeau, A. 421,452 Jellinger, K., see Bernheimer, 858,882 Juorio, A. V. 114, 115, 116, 141, H. 848, 856, 883 Jonason,J. 166,178, 816, 839 178 Jelinkova, M., see Hruza, Z. - see Almgren, O. 752, 756 - Vogt, M. 117, 147,178,637, 170,178 - see Rutledge, C. O. 495, 534 638,655 Jenkins, R. 860, 869, 890 Jonasson, J., Rosengren, E., Jurna, 1., Rummel, W. 796, 808 Jenkins, R. B., Groh, R. H. Waldeck, B. 245, 265 -- Schafer, H. 796, 808 865,890 Jones, A. 720 - see Bleckman, 1. 796, 803 Jenkinson, D. H., Morton, 1. K. - see Trendelenburg, U. 687, Jutisz, M., see Fromageot, C. M. 298,319, 332,795,808 705,709,724 112,176 - Stamenovic, B. A., Whita• Jones, A. B., see RodbeIl, M. ker, B. D. L. 800, 801, 808 382,384,457 Kabela, E., JaIife, J., Peon, C., Jepson, J. B., see Coulson, W. Jones, B. J., Roberts, D. J. 470, Cros, L., Mendez, R. 318, F. 853, 877, 885 528 332 - see Shaw, K. N. F. 877, 896 Jones, C. J., see Clarke, D. E. Kadzielawa, K. 355,476, 359 Jequier, E. 709, 720 747, 756,814,837 - Widy-Tyszkiewicz, E. 496, - Robinson, D. S., Lovenberg, Jones, F. T., see De Eds, F. 497,501,504,529 W., Sjoerdsma, A. 879, 890 877,878,886 Kahler, H. J., Heilmeyer, L. Jerrome, D. W., see Blaschko, Jones, 1. C., see Wright, A. 20, 853,890 H. 593, 601, 606, 906, 907, 44 Karki, N. T. 170,178,195,225 908, 909, 911, 924 Jones, J. D., see Cremer, G. M. - Kuntzman, R., Brodie, B. Jespersen, J., see Bonaccorsi, 915,925 B. 118,178 A. 732, 756 Jones, K. B., Quilliam, J. P. Kaser, H. 900, 912, 918, 920, Job, C., Lundberg, A. 685, 688, 662, 720 921,928 720 Jones, N. F., Walker, G., Ruth• - Tiirler, K., Burri, P. H. 919, Jobin, M., see Andersson, B. ven, C. R. J., Sandler, M. 928 484,519 851, 890, 913, 916, 928 - Wagner, H. P., Kiiffer, F. Joel, C. D. 409, 411, 450 Jones, N. L., see Havel, R. J. 922,928 Jofre, 1. J., Izquierdo, J. A. 404,449 - see Donath, A. 901, 905, 136,178 Jonsson, G., Hamberger, B., 912,913,925 - see Izquierdo, J. A. 507, Malmfors, T., Sachs, C. 203, - see Studnitz, W. v. 920, 921, 528 225 932 Joh, T. H., see Goldstein, M. - Sachs, C. 611 Kahn, J. B., see Vanderipe, D. 196,223,903,926 - see Corrodi, H. 80, 105 R. 341, 362 Johansson, B., Roos, B.-E. 859, - see H6kfelt, T. 47, 56, 58, Kaindl, F., Euler, U. S. von 890 63,75 479,529 Johnels, A. G., Palmgren, A. Jonsson, J., see Grobecker, H. Kaiser, G. A., see Chidsey, C. 17,42 341,358 A. 626, 653 - see Augustinsson, K. B. Jordan, A. L., see Hartman, W. Kajikawa, K., see Oka, M. 239, 134,171 J.92,107 246,248,254,266,542,614 Johnsen, 0., see Bygdeman, S. Jordan, C. C., see Buckley, G. A. Kajinuma, H., Kaneto, A., Ku• 209,220 299,330 zuya, T., Nakao, K. 422, Johnson, A. H., see Buse, M. Jori, A., Carrara, M. C., Garat- 451 G. 423, 444 tini, S. 501, 504, 528 Kakimoto, Y., Armstrong, M. Johnson, B., see Persson, H. - Garattini, S. 501, 528 D. 189, 225, 629, 655 298,327,334 - see Garattini, S. 500, 525 - see Sano, 1. 118, 155, 182 Johnson, G. A., Boukma, S. J., Jost, A., see Margolis, F. L. Kakiuchi, S., RaIl, T. W. 427, Kim, E. G. 503, 504, 528 903,929 428, 451 - Kim, E. G., Veldkamp, W., Jost, J.-P., Hsie, A., Hughes, S. -- McIlwain, H. 427, 451 Russel, R. 502, 528 D., Ryan, L. 375, 450 - see Rail, T. W. 427, 456 Johnson, G. E., Mickle, D. 625, Joubert, M., see Barbeau, A. Kako, K., see Wegmann, A. 632,655 858,882 198,230 - Pugsley, T. A. 628, 638, 640, Jowett, A., see Foo, J. W. 307, Kalas, J. P., see Zarafonetis, C. 655 331 J. D. 116, 142,185 - Ritzen, M. 621, 655 Joyce, D. 856, 890 Kalinina, N. A., Repin, 1. S. - see Steiner, G. 409, 459 Judah, J. D., Nicholls, M. R. 483,529 Johnson, J. C., see Van der 377,451 KaJman, G., see CsiIIik, B. 786, Wende, C. 857, 898 Jukes, M. G. M., see Anden, 787,805 Johnson, J. R., see Asatoor, A. N.-E. 518, 519 Kalsner, S. 341, 359 M. 877, 881 - see Jankowska, E. 518, 528 - Nickerson, M. 274, 278, 281, Johnson, M. C., see Melville, K. Jungas, R. L. 381, 382, 383, 304,332,727,728,738,744, 1.494,531 388,451 750, 752, 759 Author Index 969

Kamano, A., see Shah, N. S. Kasa, P., see Hebb, C. 125, Kelleher, R T., see Cook, L. 852,896 177 478,523 Kamberi, 1. A., Mical, R. S., Kashimoto, T., see Kawasaki, Kellett, G., see Wycis, H. T. Porter, J. C. 866, 890 A. 406, 451 869,899 Kamijo, K., Koelle, G. B., Kasuya, Y., Goto, K. 727,738, Kellow, A. H., see Smith, 1. Wagner, H. H. 271, 281 759 850,851,855,896 Kamin, D. L., see Kirshner, N. Katese, R. Y., see Brantigan, Kelly, A. R, see Moorhead, E. 236,251,265 C. O. 900, 924 L. 900, 901,929 Kamo, M. 140, 178 Kathan, R, see Rosenthal, 1. Kelly, M., Sharman, D. F., Te• Kanaoka, Y., see Daly, J. W. M. 903, 905, 909, 918, 920, gerdine, P. 132, 178 857,886 930 Kemp, R G., see Delange, R. J. Kaneko, Y., McCubbin, J. W., Kato, Y., see Imura, H. 435, 401,403,445 Page, 1. H. 494, 511, 529 450 Kennard, M. A., see Jacobsen, - see McCubbin, J. W. 494, Katz, A. M. 397, 451 C. F. 516, 528 495,530 Katz, B. 265, 584, 594, 611, Kennedy, B. L., see Ellis, S. Kaneto, A., Kosaka, K.,Nakao, 664,693,720 319,331,376,440,446,451 K. 422, 451 - Miledi, R 589, 611, 692, Kennedy, 1., see Farmer, J. B. - see Kajinuma, H. 422, 451 693, 720 324,331 Kanno, T., see Douglas, W. W. - see Del Castillo, J. 714, 717, Kennedy, J., see Schayer, R. 585, 586, 589, 608, 693, 717 802,805 W.270,272,281 Kanno, Y., Loewenstein, W. R. - see Fatt, P. 675, 683, 702, Kennedy, J. S., Symington, T., 564,611 717 Woodger, B. A. 902, 906, Kansal, P. C., Buse, M. G. 422, Katz, J., Landau, B. R., 928 451 Bartsch, G. E. 389, 451 Kenney, F. T., see Hager, C. B. Kanuke, K., see Yoshida, H. - Rognstad, R 389, 451 375,376,449 852,899 - see Rognstad, R 389, 390, - see Holten, D. 376, 450 Ka6, C. Y. 586, 611 457 - see Wicks, W. D. 375, 461 Kapeller, K., Mayor, D. 53, 60, Katz, R 1., Kopin, 1. J. 588, Kent, N., see Bueding, E. 405, 71,75,602,826,839 611 406,444 - see Banks, P. 53, 60, 72 Katzung, B. G., see Grunden, Kerkut, G. A., Horn, N., Wal• Kapeller-Adler, R 6, 14 L. R. 470, 471, 479, 527 ker, R. J. 96, 97,107 Kaplan, E. H., see Schayer, R. Kaufman, B., see Cotzias, G. C. - Sedden, C. B., Walker, R W. 270, 281 863,864,885 J. 82, 89,94, 95,96,107 Kaplan, M., see Smith, A. A. Kaufman, L., see Rossi, P. 913, - Thomas, R C. 686, 720 880,896 930 - Walker, R. J. 97, 107 Kappers, J. A. 428, 451 Kaufman, R, see Whitlock, J. - see Marsden, C. A. 81, 82, Karam, J. H., Grasso, S. G., P., jr. 425, 426, 461 89, 90, 91, 94, 96, 107 Wegienka, L. 0., Grodsky, Kaufman, S. 850, 890 - see Sedden, C. B. 82, 93, 94, G. M., Forsham, P. H. 422, - Friedman, S. 189, 225 108 451 - see Levin, E. Y. 189, 226, - see Walker, R. J. 97, 98, 109 Karczmar, A. G., see Scudder, 231,250,266,503,530 - see Woodruff, G. N. 97, 109 C. L. 118,182 Kauko, L., see Eranko, O. 25, Kernan, R. P., see Dockry, M. Kardaman, S., see Klingman, 41 798,805 G. 1. 165, 179 Kaumann, A. J. 304, 333, 749, Kerrpola, W. 371, 451 Karim, S. M. M. 508, 529 750, 751, 759 Kerstell, J., see Anden, N.-E. Karlson, P., Sekeris, C. E., Se• - see Izquierdo, J. A. 750, 758 865, 866, 872, 874, 875, 881 keri, K. E. 99, 107 Kauri, T., see Elofsson, R. 99, Kessler, J. T., see McDowell, F. - see Sekeris, C. E. 99, 108, 100,106 H. 861, 891 853,876,896 Kawamura, Y., see Stuart, D. Ketteler, H. J., see McGrath, Karnauchow, P. N. 922, 928 G. 494, 536 W. R 501, 530 Karnovsky, M. J., see Shea, S. Kawasaki, A., Kashimoto, T., Ketterer, H., see Unger, R. H. M.602,615 Yoshida, H. 406, 451 422,460 Karoum, F., Poliakoff, S., Kayaalp, S. 0., McIsaac, R J. Kety, S. S., see La Brosse, E. H. Ruthven, C. R J., Sandler, 584, 611, 612, 711, 720 275,281,903,928 M. 876, 877, 890 - Turker, R K. 584, 612 Key, B. J., Marley, E. 464, 471, - see Bonham Carter, S. 850, Kazarova, E. K., Esayan, N. A. 474,475,485,512,529,873, 883 128,165,178 890 - see CaIne, D. B. 855, 859, Keech, M. K., see McCann, D. - see Marley, E. 471, 474, 475, 874,875,876,877,884 S.876,891 476,477,531 - see Goodwin, B. L. 858, 866, Kehoe, J. 98, 107 Keynes, R D., see Hodgkin, A. 888 Kelkar, V. V., see Gulati, O. S. L.611 - see Ruthven, C. R J. 874, 339,358 Khairallah, P. A., see Palaic, D. 894 Kelleher, J., Watters, G., Ro• 500,533 - see Sandler, M. 848, 851, binson, R, Smith, P. 912, Khan, 1. A., see O'Gorman, L. 874,878,895 928 P.866,874,876,893 970 Author Index

Kharkevich, D. A. 661, 694. Kirpekar, S. M., see Furchgott, Klainer, L. M., Chi, Y.·M., 720 R. F. 212, 223, 303, 304, Freidberg, S. L., RaIl, T. Khassis, S., see Gitlow, S. E. 332,353,354,358,634,654, W., Sutherland, E. W. 401, 912,926 730, 731, 757 427,451 Kicic, M., see Micic, R. 902, - see Gillespie, J. S. 176, 199, Klawans, H. L., jr., Garvin, J. 929 202,209,210,223,568,576, S., Shekelle, R. B. 869, 872, Kidder, G. W., see Janakidevi, 609,610 890 K. 81, 85, 107 Kirshner, A. G., Kirshner, N. - Weiner, W. 890 Kier, L. B., Truitt, E. B., jr. 250,265,580,612 Kleeman, C. R., see Liberman, 854,890 - see Kirshner, N. 244, 246, B. 433, 453 Kiesewetter, W. B., see Koop, 249,250,258,265,540,555, Klein, D. C., Berg, G. R., WeI· C. E. 917, 928 557,560,562,565,587,612 ler, J. 429, 430, 451 Kikuchi, T. 496, 529 Kirshner, N. 31, 42, 204, 225, --- Glinsmann, W. 429, Kilbinger, H., Lindmar, R., 232,233,236,243,244,245, 430,451 LOffelholz, K., Muscholl, E., 246,250,254,255,265,498, - Rowe, J. 430, 451 Pati!, P. N. 624, 626, 633, 529,539,544,546,557,558, - Weller, J. L. 430, 431, 451 634,637,642,643,648,649, 589, 596, 612, 853, 890 Klein, L. A., see Liberman, B. 650,655 - Goodall, McC. 31, 42, 231, 433,453 Kilsheimer, G. S., see Christian, 265 Kleinschmidt, A., Schiimann, D. R. 394, 395, 444 - Holloway, C., Kamin, D. L. H. J. 909, 928 - see Claycomb, W. C. 374, 236,251,265 Klemm, N. 86,101,107 445 -- Smith, W. J., Kirshner, Klensch, H. 131, 178 Kim, E. G., see Johnson, G. A. A. G., 244, 246, 249, 250, Klerman, G. L., Schildkra.ut, J. 502,503,504,528 258,265 J., Hasenbush, L. L. 862, Kim, H. C., D'Iorio, A. 6, 14 - Rorie, M., Kamin, D. L. 890 Kim, T. S., Shulman, J., Le· 236,265 Klinge, E. 164, 178 vine, R. A. 406, 451 - Sage, H. J., Smith, W. J. Klingman, G. I. 156, 178, 813, Kimmich, G. A., Rasmussen,H. 68,75 814,816,821,822,828,830, 372,377,451 --- Kirshner, A. G. 540, 839 Kimura, K., see Takagi, H. 498, 555,557,560,562;565,587, - Kardaman, S., Haber, J. 536 612 165,179 King, E. C., see Welsh, J. H. - Smith, W. J. 213, 225, 595, - Klingman, J. D. 822, 831, 81,87,109 612 839 King, M., see Angelakos, E. T. Klingman, J. D., see Klingman, 115,137,139,140,160,171 - Viveros, O. H. 595, 612 G. I. 822, 831, 839 Kipnis, D. M., see Bourgoignie, - see Anlyan, W. G. 861, 881 Klouda, M. A. 160, 179 J.443 - see Blum, J. J. 85, 105 Kluge, A., see Wiist, G. 913,933 - see Cryer, P. E. 382, 445 - see Boyarsky, S. 170,173 Knill·Jones, R. P., see Godwin· - see Hertelendy, F. 422, 449 - see Connett, R. J. 562, 607 Austen, R. B. 870, 887 - see Horino, M. 422, 450 - see Duch, D. S. 540, 557, - see Parkes, J. D. 869, 893 - see Turtle, J. R. 386, 419, 559,608 Knoche, H., Alfes, H., Moell. 420,421,433,434,460 - see Ferris, R. M. 244, 245, ma.n, H. 113, 130, 179 Kirby, K. C., jr., Swem, D., 248,255,257,258,264,595, Knox, W. E. 854, 890 Baserga, R. 426, 451 596,609 - see Csanyi, V. 375, 445 Kirk, G., see Farrugia, M. T. - see Goodall,McC. 4, 13, 187, KnyiMr, E., see Csillik, B. 786, 624,653 188, 223, 815, 838 787,805 Kirkendall, W. M., Liechty, R. - see Kirshner, A. G. 250, 265, Kobayashi, H., Hirano, T., D., Culp, D. A. 901,928 580,612 Oota, Y. 67, 75 Kirkland, R. J. A., see Whitta· - see Mannarino, E. 467, 469, - Libet, B. 675, 683, 707, 720, ker, V. P. 37, 44, 617 504,505,531 788,789,808 Kirkpatrick, W. E., see Lomax, - see Sage, H. J. 34, 44, 540, - see Libet, B. 678, 707, 721, P.481,482,530 555,615 788,789,809 Kirpekar, S. M., Cervoni, P. - see Viveros, O. H. 34, 44, Kobayashi, S. 23, 42 211,225,240,265 239, 246, 250, 254, 257, 261, Kobayashi, T. 470, 529 -- Couri, D. 548, 568, 612 269,540,542,551,553,555, Kobayashi, Y., see Schayer, R. -- Furchgott, R. F., 156, 556,557,558,559,560,565, W. 270, 272,281 157,178,787,808,814,815, 587,595,598,600,604,617 Koch, J. P., see Resnick, R. H. 817,839 Kisin, I. E. 651, 652, 655 880,894 - Furchgott, R. F. 354, 359 Kiss, T. 34, 42 Koch, R., see Shaw, K. N. F. - Goodland, G. A. J., Lewis, Kissel, J. W., Domino, E. F. 921,931 J.J. 548, 612 515,516,517,529 Koch·Weser, J. 745, 759 - Misu, Y. 568, 588, 612, 693, Klaas, D., see Rafael, J. 412, Koe, B. K., Weissman, A. 866, 720, 781, 782, 808 456 890 - Wakade, A. R. 213, 225, Klahr, S., see Bourgoignie, J. - see Weissman, A. 498, 502, 588,612,781,782,808 443 537 Author Index 971

Koelle, G. 34, 42 Kopin, 1. J., Hel'tting, G., Kosterlitz, H. W. 796, 808 Koelle, G. B., De T. Valk, A. Gordon, E. K. 278, 281 - Cowie, A. L. 795, 809 271,281 - Weise, V. K., 235, 266, 498, - Lees,G.M. 584, 634, 776,809 - see Dolivo, M. 705, 717 529, 640, 655 -- Wallis, D. 1. 663, 673, - see Kamijo, K. 271, 281 -- Sedvall, G. C. 639, 640, 675,678,680,682,691,695, Koepp, W., see Holtz, P. 188, 641,655 696, 697, 703, 721, 789, 809 224, 852, 875, 889 - see Axelrod, J. 338, 357, - Lydon, R. J., Watt, A. J. Kohei, H., see Akabane, J. 587, 912,924 792, 793, 794, 795, 809 605 - see Baldessarini, R. J. 499, - Robinson, J. A. 792, 809 Kohl, M., see Sacks, O. W. 519,588,605 - Thompson,J. W., Wallis,D. 861,865,894 - see Fischer, J. E. 278, 280, 1. 663, 690, 721 Kohli, J. D. 298, 300, 333 618,621,626,631,632,633, - Wallis, D. 1. 663, 676, 721 - Ling, G. M. 314, 333 642,653,776,806,816,837 - Watt, A. J. 298, 333 - see Innes, 1. R. 341, 359 - see Gewirtz, G. P. 575, 579, - see Cowie, A. L. 795, 796, Kohn, A. 16, 42, 783, 808 609 805 Kohout, M., see Heimberg, M. - see Glowinski, J. 50, 74, 198, - see Innes, 1. R. 737, 758, 373, 374, 375, 449 218,223,465,467,468,469, 833,839 Kojiri, K., see Ayukawa, S. 504, 526, 820, 838 Kottegoda, S. R. 764, 809 191,219 - see Hertting, G. 198, 208, Kovacsics, G. B., see Saelens, Koketsu, K. 675, 683, 695, 707, 209,212,213,224,813,816, J. K. 112, 134, 149,182 720,789,808 833,838 Krakoff, L. R., Axelrod, J. 232, - Nishi, S. 663, 666, 670, 678, - see Katz, R. 1. 588, 611 266 683, 696, 720, 721 - see Krauss, K. R. 630, 655, - see Eisenfeld, A. J. 209, 222, -- Noda, 't. 678, 696, 721 774, 777, 809 278,280,747,748,749,757 -- Soeda, H. 695, 696, 721 - see La Brosse, E. H. 903, Kramer, E. R., see Chessin, M. - see Abood, L. G. 256, 261 928 194,221 - see Nishi, S. 664, 668, 669, - see Musacchio, J. M. 193, Krantz, K. D., Seiden, L. S. 671,673,674,675,676,677, 201,216,227,337,338,352, 504,529 683,684,685,688,690,695, 360,503,532,619,620,621, Krasner, N., Cornelius, J. M. 722,789,810 625,626,632,633,635,636, 861,890 Koll, J. F., see Sack, H. 900, 645,656 Krassoievitch, M., see De Aju• 930 - see Ng, K. 't. 872, 879, 893 riaguerra, J. 877 Komalahiranya, A., Volle, R. - see Poch, G. R. 338, 361, Krause, E. G., Wollenberger, L. 713, 721 636,657 A. 399, 452 Kondo, S. 482, 529 - see Potter, L. T. 468, 533, - see Wollenberger, A. 399, Konishi, M., see Ochi, J. 52, 76 629,658 462 Konno, N., see Kuroshima, A. - see Schanberg, S. M. 467, Krauss, K. R., Carpenter, D. 408,411,452 468,499,534 0., Kopin,1.J. 774, 777, 809 Kono,T. 382,384, 385, 386,451 - see Schildkraut, J. J. 500, - Kopin, 1. J., Weise, V. K. Kontras, S. B. 920, 921, 928 535 630,655 Konzett, H. 709, 721, 750, 759 - see Sedvall, G. 194, 228, - see Kopin, 1. J. 196, 225, - see Hebb, C. O. 737, 758 235,267,639,658,813,816, 573,612 Koop, C. E., Kiesewetter, W. 822,828,841 Krautheim, J., see Schmid, E. B., Horn, R. C. 917, 928 - see Wurtman, R. J. 198, 914,931 Koop, G. E., see 'toung, R. B. 230, 274, 282, 816, 844 Kravitz, E. A., see Iversen, L. 920,921,933 Koppanyi, T., see Maengwyn• L. 204,225 Kopin, 1. J. 4, 14, 235, 241, 266, Davies, G. D. 354,360 Krayenbiihl, H., Siegfried, J. 270,275,276,281,545,565, - see Wurzel, M. 314,335 863,869,891 572,612,618,620,636,643, Korduba, C. A., Veals, J., Krayer, 0., Alper, M. H., Paa• 650,655,863,879,890 Symchowicz, S. 880, 890 sonen, M. K. 355, 359 - Axelrod, J. 906, 928 KorEmyi Both, A., see Viragh, - see Paasonen; M. K. 336, -- Gordon, E. K. 276, 281 S.22, 27, 30, 39, 44 354,360 - Breese, G. R., Krauss, K. Kork, A. E., see Pertsemlidis, Krebs, E. G., see Brostrom, lVI. R., Weise, V. K. 196, 225, D. 901, 913, 930 A. 404, 443 573,612 Kormano, M. 872, 890 - see Corbin, J. D. 388, 445 - Bridgers, W. 349, 359 Kornacker, M. S., Ball, E. G. - see Delange, R. J. 401, 403, - Fischer, J. E., Musacchio, 409, 411, 412, 451 445 J. M., Horst, W. D., Weise, Korol, B., Soffer, L., Brown, - see Huston, R. B. 403, 450 V. K. 205, 208, 225, 338, M. L. 648, 655 - see Posner, J. B. 401, 402, 352,359,619,621,626,629, Kosaka, K., see Kaneto, A. 404,456 633, 642, 646, 655 422,451 - see Riley, W. D. 404, 457 - Gordon, E. K. 209, 210, 217, Kosersky, D. S., see Hancock, - see Walsh, D. A. 401, 461 218,225,276,277,281 C. 705, 719 Krebs, H. A., see Gevers, W. -- Horst, W. D. 274, 275, Kosman, M. E., Gerard, R. W. 372, 377, 448 281, 502, 529, 816, 839 479,529 - see Ross, B. D. 374, 458 972 Author Index

Kreisberg, R.-A. 394, 452 Kuntzman, R., see Gessa, G. L. Ladisch, W., see Schubert, P. - see Williamson, J. R. 371, 497, 526, 619, 636, 654 467,535 374,462 - see Gillette, J. R. 499, 500, Laduron, P. 235, 236, 248, 249, Krell, R. D., see PatiI, P. N. 526 266 329,334 - see Karki, N. 1I8, 178 - Belpaire, F. 31, 42, 233, 239, Kremer, M., Russell, W. R., Kuntzman, R. G., see Shore, 240,243,246,254,266,539, Smyth, G. E. 847, 891 P. A. 272, 281 542,572,576,578,600,602, Krijgsman, B. J. 101, 107 Kuo, J. F. 381, 452 612 - Divaris, G. A. 98, 107 - De Renzo, K C. 381, 382, - De Potter, W., De Schaep• Kris, A. 0., Miller, R. E., Wher• 383,452 dryver, 214, 225 ry, F. E., Mason, J. W. 422, - Greengard, P. 365, 369, 394, - see Belpaire, F. 233, 262, 452 401,452 540,557,559,606 Krishnamurty, V. S. R., see - see Miyamoto, K 428, 454 L'age, M., see Seubert, W. 373, Gulati, O. D. 299, 314, 315, Kuperminc, D., see Buse, M. 458 332 G. 423, 444 Lagercrantz, H. 212, 225 Krivoy, W. A., Wills, J. H. 703, Kuriyama, H., see Burnstock, - Kuylenstierna, R, Stjarne, 721 G. 693, 716 L. 250,266 Krnjevi6, K., MiIedi, R. 800, - see Hidaka, T. 802, 808 - Pertoft, H., Stjarne, L. 248, 801,809 Kuroshima, A., Konno, N., 249,250,266 - Phillis, J. W. 497, 529 Itoh,S.408,411,452 - see Stjarne, L. 217, 229, - see Eccles, J. C. 694, 717 Kurpys, see Bloom, F. E. 67 249,268,574,616 Kroneberg, G., Schlossmann, Kurti, A. M., see Fekete, M. Lagerlof, R, see Gejrot, T. 923, K., Haberland, G. 750, 759 854,863,887 926 - Schiimann, H. 234, 266, Kuruma, 1., Bartholini, G., Lagerstedt, S., see Hillarp, N.- 498,529 Pletscher, A. 876, 891 A.5,14,248,265,539,610 - Stoepel, K. 619, 631, 655 - see Bartholini, G. 877, 882 Laidlaw, P. P. 864,891 - see Holtz, P. 132,177 Kuttner, R., Sims, J. A., Gor• Lajtha, A. 464, 465, 474, 529 Krop, S., see Hanig, J. F. 873, don, W. 465,529 - Toth,J. 465,530 888 Kuylenstierna, B., see Lager• Lall, A., see Biscoe, T. J. 23, 24, Kruk, E., see Gitlow, S. E. 912, crantz, H. 250, 266 39 926 Kuzmina, L. V., see Plotniko• Lambert, A. E., Jeanrenaud, Kuba, K. 801, 809 va, S. 1. 88,108 B., Renold, A. E. 420, 452 Kiiffer, F., see Kaser, H. 922, Kuzuya, H., see Nagatsu, T. -- Junod, A., Renold, A. E. 928 557,613 421,452 Kuehl, F. A., jr., Vandenheu• Kuzuya, T., see Kajinuma, H. - Junod, A., Stauffacher, W., vel, W. J. A., Ormond, R. 422, 451 Jeanrenaud, B., Renold, A. E. 850,891 - see Porte, D. 419, 422, 456 E. 421, 452 Kuffler, S. W., see Dudel, J. Kvale, W. F., see Gifford, R. Lammerant, J., see De Schry• 702, 717 W.900,926 ver,C. 159, 170,182 Kujalova, V., see Mosinger, B. - see Priestley, J. T. 901, 91I, Lammers, A. J., van Rossum, 382,454 930 J. M. 496, 530, 863, 865, Kukovetz, W. R .. Lembeck, F. 891 - see Roth, G. M. 901, 930 Lancaster, G., Larochelle, L., 738, 759 Kypson, J., Triner, L., Nahas, - Poch, G. 394, 395, 396, 452 G. G. 382, 383, 452 Bedard, P., Missala, K., Kulenkampf, C., see Degkwitz, Sourkes, T. L., Poirier, L. J. R. 860, 886 Labay, P., see Boyarsky, S. 847,868,891 Kulkarni, A. S. 471, 476, 483, 170,173 Lancaster, S. 89, 107 529 Lance, E. M., Cate, W. R., Lid• Kullnig, R. K., see Archer, S. La Brosse, E. H., Axelrod, J., dle, G. W., Scott, H. W. 913, 506,519 Kety, S. S. 275, 281 928 Kunos, G., Szentivanyi, M. 299, -- Kopin, 1. J., Kety, S. S. Landau, R R., see Katz, J. 333 903,928 389,451 Kuntz, A., Saccomanno, G. -- Sjoerdsma, A. 912, 928 Landez, J. H., see Wykes, A. 688, 721 - Belehradek, J., Barski, G., A. 192,230 Kuntzman, R., Costa, E., Cre· Bohuon, C., Schweissguth, Lands, A. M., Arnold, A., Mc• veling, C. R., Hirsch, C., 0.917,928 Auliff, J. P., Luduena, F. P., Brodie, R B. 505, 529 - Schweissguth, 0., Bohuon, Brown, T. G. 286, 320, 321, - Creveling, C., Hirsch, C. W., C.919,928 324, 325, 329, 333 Brodie, B. R 192,225 - see Bohuon, C. 917, 924 - Groblewski, G. K, Brown, - Shore, P. A., Bogdanski, D., - see Imashuku, S. 917, 927 T. G. 320, 324, 325, 333 Brodie, B. R 150, 179 Lacy, P. E., Howell, S. L., - Luduena, F. P., Buzzo, H. - see Brodie, R R 192, 220, Young, D. A., Fink, C. J. J. 286, 320, 321, 323, 324, 497,521 420,421,452 325,333 - see Costa, E. 497, 523, 787, - Young, D. A., Fink, C. J. Landsberg, L., Axelrod, J. 196, 791,805 420,452 226 Author Index 973

Landsberg, L., De Champlain, Lapidus, J. B., see Tye, A. 346, Laties, A. M., Jacobowitz, D. J., Axelrod, J. 195, 226 351,362 121,179 - see Eisenfeld,A.J. 747, 751, Lapis, K., see Benedeczky, 1. Latta, H., see Barajas, L. 52, 757 25,39,909,911,924 72 - see Molinoff, P. 629, 656 Laplace, J. P., see Ruckebusch, Lattimer, J. K., see Tannen• Langan, T. A. 369, 452 1'.482,484,491,534 baum,M.909,932 Langemann, H. 3, 14, 188, 226, Laporte, 1'., Lorente de N6, R. Lau, S. H., see Thurm, R. H. 853,891 676,677,678,682,688,690, 914,933 - Ackermann, H. 854, 891 721 Lauber, E., see Goldstein, M. - Boner, A., Miiller, P. B. - see Lorente de N6, R. 685, 189,193,201,223,503,506, 853, 891, 902, 928 690, 722 526, 624, 654, 814, 838 - see Blaschko, H. 188, 220, Laragh, J. H., see Buhs, R. P. Laumonier, R., Marche, C., 619, 652, 852, 883 620,652 Marche, J. 909, 928 - see Burn, J. H. 122, 158, Laraia, P. J., Craig, R. J., Red• Laurence, D. R., see Bonham 173 dy, W. J. 395, 452 Carter, S. 851, 883 - see Ziegler, W. H. 905, 933 Laren, F., see Wurtman, R. J. - see CaIne, D. B. 861, 865, Langeman, N. H., see Burger, 431, 462, 823, 844 873,884 M. 904, 905, 906, 925 Larin, F., see Wurtman, R. J. - see Hunter, K. R. 863, 867, Langendorff, O. 832, 839 851,899 869,870,889,890 Langeneckert, W., see Palm, Lariviere, E. W., see Moore, K. Laurin, C., see Cordeau, J. P. D. 297, 334, 648,657 E. 119,180 476,523 Langer, G. A. 397,452 Larner, J. 369, 370, 452 Laursen, T., Davidsen, G., Langer, S. Z. 340, 359, 569, 612, - Sanger, F. 401, 452 Hasner, E. H., Lindberg, J., 734, 735, 749, 750, 751, 753, - Villar-Palasi, C., Goldberg, S0rensen, B. 912, 928 754, 759, 817, 818, 839 N. D., Bishop, J. S., Hui• Laverack, M. S., see Chanussot, - Bogaert, M. G., De Schaep• jing, F., Wenger, J. 1., Sas• B. 101,105 dryver, A. E. 754, 759 ko, H., Brown, N. B. 404, - see Cottrell, G. A. 85, 106 - Drask6czy, P. R., Trende• 452 Laverty, R., Phelan, E. L. 831, lenburg, U. 340, 359, 727, - see Bishop, J. S. 370, 443 839 733,734,738,747,754,759, - see Craig, J. W. 401, 404, - Sharman, D. F. 112, 115, 817,818,833,839 445 118, 119, 120, 148, 149, 152, - Trendelenburg, U. 307, 308, - see Goldberg, N. D. 404, 448 153,154,156,179,787,809, 309,313,327,333,726,727, - see Huijing, F. 393,450 855,891 730, 734, 738, 744, 745, 746, - see Rosell-Perez,M. 401, 457 -- Vogt, M. 159,179, 823, 747,754,759,817,839 Laroche, M. J., see Axelrod, J. 826,839 - see Hoszowska-Owczarek, 272,273,279,506,519,814, - Taylor, K. M. 112, 179, 859 A. 353,359 836 - see Dagirmanjian, R. 495, - see Iversen, L. L. 749, 758, Larochelle, L., see Bedard, P. 496,523 813,816,822,839 847,851,882 - see Devine, C. E. 56, 73 - see Jarrot, B. 752, 759 - see Lancaster, G. 847, 868, - see Faull, R. L. M. 847, 856, - see Pluchino, S. 734, 760 891 886 - see Smith, C. B. 157, 183, Larrabee, M. G. 594, 612, 662, - see Taylor, K. M. 872, 874, 734,760,815,817,818,833, 721 897 842 - Bronk, D. W. 682, 686, 687, Lavis, V. R., Williams, R. H. - see Tsai, T. H. 343, 344, 345, 721 385,452 351,362 - Leicht, W. S. 594, 612 Law, W., see Crawford, T. B. - see Van Orden, L. S. 46, 52, - see Bronk, D. W. 663, 682, B. 170,174 56, 78, 348, 362, 729, 734, 690,716 Lawrence, A. M. 915, 928 761, 814, 817, 833, 843 Larsen, K., see Fonnum, F. - Forland, M. 915, 928 - see Weiner, N. 814, 817, 867,887 Lawrentjew,B. J. 784, 809, 814, 843 Larson, A. M., see Hannon, J. 839 Langley, J. N. 9, 284, 333 P.485,527 - Borowskaja, A. J. 814, 830, Langley, P., see Burns, T. W. Larsson, B., Owman, C., Sund• 839 381, 386, 444 ler, F. 133,179 Lawson, J. W., see Manley, E. Langwinski, R., see Maj, J. 341, - see Falck, B. 126, 161, 176 S.299,333 360 Larsson, K., see And{m, N.-E. Layne, D. S., see Drujan, B. D. Lapan, E., see Applewhite, P. 847,881 121, 170, 174 B. 81, 85,105 - see Butcher, L. L. 853, 854, Lazare, R., see Davis, R. A. Lapidus, J. B., Tye, A., Patil, 866,884 192,221 P. N. 302, 333 Larsson, S., see Andersson, B. - see Drain, D. J. 497, 524 - see Patil, P. N. 344, 346, 490,494,519 Leach, C. S., Lipscomb, H. S. 347,352,360,623,657 Lasagna, L., see Prescott, L. F. 32,42 - see Seidehamel, R. J. 746, 620,658 Leach, G. D. H., see Finch, L. 747, 760 - see Rivera-Calimlim, L. 814,828,837 - see Swamy, V. C. 649,659 871,894 Leaders, F. E. 762, 809 974 Author Index

Leaders, F. E., Dayrit, C. 575, Leibowitz, S. F. 490, 510, 530 Lever, J. D., see Graham, J. 612, 762, 765, 809 Leibson, L. G., Stabrovskii, E. D. P. 53, 56, 74, 584, 610, Le Blanc, J., Robinson; D., M.117,179 780,807 Sharman, D. F., Tousig. Leiby, C. M., see Porter, C. C. Levey, G. S. 393, 453 nant, P. 132, 179 497,498,533,619,636,639, - Epstein, S. E. 392, 393, 396, - see Baldwin, B. A.171 657 397,453 Leboeuf, B., see Renold, A. E. Leicht, W. S., see Larrabee, M. - Skelton, C. L., Epstein, S. 390,457 G. 594, 612 E. 392,395, 397, 453 Lebovitz, H. E., Pooler, K. Leick, J., see Burford, H. 743, - see Entman, M. L. 377, 393, 422,452 756 396,397,447 Lech, J. J., see Calvert, D. N. Leiderman, E., see Beltran, G. - see Skelton, C. L. 395, 396, 385,444 924 459 Lechner, K., see Ehringer, H. Leimdorfer, A. 469, 511, 512, Levi, A. J., see Asatoor, A. M. 190,222 514,530 877,881 Le Compte, P. M. 923, 928 - Arana, R., Hack, M. A. 470, Levi, R, see Maynert, E. W. Lecomte, J., see Bacq, Z. M. 471,530 119,180 114,171 - Metzner, W. R T. 469, 470, Levi-Montalcini, R 819, 820, - see Bruel, van den, W. 128, 471,530 831,839,840 159,167,173 Leitz, F. H., Stefano, F. J. E. - Angeletti, P. V. 11,14, 167, - see Lefebvre, P. J. 915, 929 213,226 179, 814, 819, 820, 821, 822, Ledebur, I. X., Tissot, R. 497, Lembeck, F., Resch, H. 750, 830,831,840 530 759 - see Angeletti, P. 819, 829, Lederer, E., see Fromageot, C. - see Kukovetz, W. R 738, 835 112,176 759 - Booker, B. 814, 819, 820, Leduc, J. 166, 167, 170, 179, Lemberger, L., see Burns, J. J. 831,840 234,266,904,928 286,331 - Cohen, S. 819, 840 - D'Iorio, A. 906, 907, 908, - see Salvador, R. A. 423, 458 - Hamburger, V. 818, 840 928 Lemberger, M., see Sih, C. J. - Meyer, H., Hamburger, V. - Dubreuil, R., D'Iorio, A. 852,896 818,840 125,179 de Lemos, C., see Pick, J. 52, - Tentori, L., Vivaldi, G., An• - Rivest, P. 417, 452 76 geletti, P. U., Marini-Bet• - see Fortier, A. 244, 264 Lempinen, M. 22, 32, 42 tolo, G. B. 819, 840 Lee, F. L. 340, 359 - see Eranko, O. 32, 41 - see Hamberger, B. 820, 821, - Trendelenburg, U. 584, 612 Lenard, J., Singer, S. J. 48, 75 822, 830, 838 - Weiner, N., Trendelenburg, Lenn, N. J. 61, 67, 71, 75 Levin, E. Y., Levenberg, B., U. 626, 655 Lentz, T. L. 85, 88, 107 Kaufman, S. 189; 226, 231, --- 338,359 - see Wood, J. G. 86, 109 250, 266, 503, 530 Lee, J. E., see McDowell, F. H. Leon, A. S., Solomon, H. M., Levin, J. A., Furchgott, R. F. 861,891 Ross, I., Golden, R. M., 304,333,752,759 Lee, K.-L., see Wicks, W. D. Abrams, W. B. 873, 891 Levin, N., see Braham, J. 850, 375,461 Leonard, R H., see Williams, 851,884 Lee, N. H., see Haugaard, N. C. M. 921, 933 Levine, M., see Sommer, S. R. 397,449 Uranth, C., see Ungvary, G. 489,535 Lee, W. C., Shideman, F. E. 688,724 Levine, R., see Penhos, J. C. 764,809 Letarte, J., Jeanrenaud, B., 374,375,455 - Shin, Y. H., Shideman, F. Renold, A. E. 382, 383, 453 Levine, R A. 371, 453 E. 355, 359 - Renold, A. E. 383, 453 - see Kim, T. S. 406, 451 - see Cha, K.-S. 127, 164,173 Lettvin, J. Y., see Schwab, R. Levine, R J., see Roth, R. H. Leeper, L. C., see Sjoerdsma, S. 863, 895 235,267 A. 902, 904, 931 Levak, see Coons 482 - Sjoerdsma, A. 192, 226, 636, Lees, G. M., see Kosterlitz, H. Levenberg, B., see Levin, E. Y. 639,655, 850, 891 W. 584, 634, 663, 673, 675, 189,226,231,250,266,503, Levine, R. L., see Roth, B. H. 678,680,682,691,695,696, 530 902,904,916,930 697, 703,721,776,789, 809 Lever, J. D. 34, 43 Levine, W. G., see Blaschko, H. Lefebvre, P. J., Cession-Fos• - Esterhuizen, A. C. 214, 226, 8,12 sion, A. M., Luyckx, A. S., 729,757,779,806,831,833, Levit, S. A., Sheps, S. G., Espi• Lecomte, J. L., Van Cau• 839 nosa, R. E., Remine, W. H., wenberge, H. S. 915, 929 - Findlay, J. A. 562, 563, 612 Harrison, E. G. 929 - see Luyckx, A. S. 422, 453 - Lewis, P. R, Boyd, J. D. Levitt, M., Spector, S., Sjoerds• Legg, P. G. 52, 75 23,43 ma, A., Udenfriend, S. 226, Lehninger, A. L. 397, 452 - Spriggs, T. L. B., Graham, 234,237,266,501,530,816, Lehr, B., see Chidsey, C. A. J.D.P.46,53, 56,58, 75 840 626,653 - see Esterhuizen, A. C. 52, - see Creveling, C. R 189, 221 Leibhold, R. A., see Hartman, 56,58,74 - see Ikeda, M. 187,225,234, W.J.92,107 - see Findlay, J. A. 422, 447 265, 619, 655 Author Index 975

Levitt, M., see Nagatsu, T. 8, Lieberman, E., see Shaw, K. N. Lindmar, R., see Loffelholz, K. 14, 187, 191, 193, 194, 227, F. 921, 931 706, 721, 741, 759 231,232,234,266,501,533, Lieberman, F., see Vaughan, - see Muscholl, E. 621, 633, 848,878,893,902,930 M. 388, 461 648,657 - see Spector, S. 187, 196,228 Liebman, J. 337, 359 Lindner, E., see Bargmann, W. - see Zhelyaskov, D. K. 501, - Muskus, A. J., Waud, D. R. 416,442 537 354,359 - see Euler, U. S. von 482, Levy, B. 286, 320, 333 Liechty, R. D., see Kirkendall, 524 - Tozzi, S. 314, 316, 333 W. M. 901, 928 Lindqvist, M., see Bertler, A. - Wasserman, M. 310, 333 Lightman, S., Iversen, L. L. 498,520 - Wilkenfeld, B. E. 286, 333 278,281,569,613,747,748, - see Carlsson, A. 5, 13, 149, - see Ahlquist, R. P. 285, 298, 750, 759 173,188,191,192,205,221, 330 Liley, A. W. 802, 809 495,496,497,498,499,503, - see Wilkenfeld, B. E. 406, Lilya, B., see Hakanson, R. 504,505,506,522,618,619, 461 133,165,177 623,626,631,636,639,653, Levy, C. K., see Smythies, J. R. Lin, Y.-C., Sturkie, P. D. 143, 878,884 478,535 179 - see Dahl, E. 17, 41, 82, 83, Levy, G. P., see Farmer, J. B. - see Sturkie, P. D. 117,184 106 323, 324, 331 Linarelli, L. G., see Glinsmann, - see Haggendal, J. 218, 223, Lewander, T. 626, 628, 655 W.H. 371, 375, 448 497,498,527 Lewis, G. P. 514, 530 Lin£ova, D., Cernohorsky, M., - see Hillarp, N. A. 904, 907, - Matthews, J. 387, 453 Cepelik, J., Miihlbachova, 927 - Reit, E. 709, 710, 721 E., Wenke, W. 387, 453 Linet, 0., Widhalm, S., Hert• Lewis, J. J., see Kirpekar, S. - see Cernohorsky, M. 301, 331 ting, G. 144, 147,179 M. 548, 612 - see Wenke, M. 291, 312, 335 - see Suko, J. 8, 15 Lewis, P. R., Shute, C. C. D. Lind, J., see Greenberg, R. E. Ling, G. M., see Kohli, J. D. 34,38,43,585,612 21,22,42 314, 333 - see Lever, J. D. 23, 43 Lindberg, J., see Laursen, T. - see Malik, K. U. 764, 773, Lhermitte, F., see Boudin, G. 912,928 781,810 867,884 Lindberg, 0., De Pierre, J., Ry• Linley, P. A., see Clarke, D. E. L'Hermite, P., see Taxi, J. 787, lander, E., Afzelius, B. A. 747,756,814,837 812 412,453 Lipscomb, H. S., see Leach, C. Li, B. L., see Gitlow, S. E. 845, - Prusinger, S. B., Cannon, S. 32, 42 887 B., Ching, T. M. 409, 412, Lipton, M. A., see McCurdy, R. Liberman, B., Klein, L. A., 413,453 L. 646, 656 Kleeman, C. R. 433, 453 - see Barnard, T. 411, 416, Lisander, B., see Folkow, B. Libet, B. 675, 678, 680, 681, 417,442 216,223,240,264,566,567, 682,686,692,721 - see Hittelman, K. J. 412, 568,569,609 - Chichibu, S., Tosaka, T. 415,450 Lisch, H.-J., Aigner, A., Hor• 678,721 - see Prusinger, S. B. 409, 412, nykiewicz, O. 148, 179 - Kobayashi, H. 678,707,721, 413,456 - see Aigner, A. 504, 518 788,789,809 - see Skala, J. 411, 416, 459 Lishajko, F. 123,179, 188,204, - Tosaka, T. 665, 677, 678, Linden, G., see Lorimier, A. de 226,242,244,246,251,252, 680, 688, 721 917,929 253,254,255,256,257,259, - see Eccles, R. M. 678, 682, Lindmar, R. 356, 359, 772, 809 266, 595, 596, 613 688,708,717,783,784,790, - Loffelholz, K., Muscholl, E. - see Bloom, G. 18, 40, 134, 806 357,359,588,590,613,706, 172 - see Kobayashi, H. 675, 683, 721, 768, 771, 772, 773, 809 - see Euler, U. S. von Ill, 707,720, 788, 789, 808 - Muscholl, E. 202, 209, 210, 112, 125, 126, 129, 156, 161, - see Tosaka, T. 674, 678, 707, 211,226,240,266,337,338, 169,175,188,189,192,195, 724 340,349,355,359,360,570, 197,199,200,201,202,203, Lickfeld, K., see Philippu, A. 588,613,622,623,627,637, 204,205,208,209,211,213, 205,227 638,644,645,647,649,655, 214,216,217,218,219,222, Liddell, D. W., see Weil-Mal• 728, 735, 736, 739, 740, 759, 244,246,253,257,258,263, herbe, H. 120,185 768, 772, 773, 774, 809 350,352,358,609 Liddle, G. W., see Abe, K. 434, -- Rahn, K. H. 627, 634, - see Ostlund, E. 134,181 441 656 - see Shahab, L. 201, 207, 228 - see Lance, E. M. 913, 928 -- Sprenger, E. 621, 625, - see Stjarne, L. 189, 193, Liddle, R. A., see Abe, K. 434, 630,633,634,635,637,642, 194,195,229,232,233,236, 441 643, 648, 650, 656 258,268,498,536,616,639, Lidvall, H.-F., Bee Gunne, L. - Bee DrewB, E.-F. 621, 625, 658,906,907,908,932 M. 852, 875, 888 637,653 Lissak, K. 783, 784, 809 Liebau, H. 914, 929 - see Kilbinger, H. 624, 626, - see Benedeczky, I. 596, 606 Lieberman, A. N., Pedersen, B. 633,634,637,642,643,648, - see Cannon, W. B. 198,221, 862,865,891 649,650,655 815,836 976 Author Index

Littleton, G. K., see Turtle, J. Losert, W., see Senft, G. 367, Lundberg,A.783,784,788,810 R. 460 422,423,458 - Thesleff, S. 700, 722 Littleton, J. M. 503, 530 Lotti, V. J., Porter, C. C. 863, - see Anden, N.-E. 518, 519 Litwack, G., see Sasaki, T. 425, 891 - see Jankowska, E. 518, 528 426,458 - see Banerjee, U. 510, 520 - see Job, C. 685, 688,720 Livett, B. G., Geffen, L. B., - see Feldberg, W. 481, 482, Lundberg, D. 817, 818, 840 Austin, L. 574, 602, 613 483, 484, 505, 524 Lundborg, P. 337, 360, 570, - see Austin, L. 194, 219 Louis, W. J., Doyle, A. E. 914, 572,613 - see Geffen, L. B. 74, 217, 929 - Stitzel, R. 243, 245, 259, 223,543,574,575,602,609 Loveland, M., see Steiner, G. 266,622,625,645,656 Ljungberg, 0., Cederquist, E., 409,459 - see Almgren, O. 621, 652 Studnitz, W. v. 901, 929 Loveland, R. E. 94, 107 - see Carlsson, A. 620, 645, - see Falck, B. 901, 905, 926 - see Welsh, J. H. 103,109 653 - see Studnitz, W. v. 914, 932 Lovenberg, W., Barchas, J., - see Stitzel, R. E. 217, 228 Ljungdahl, A., see Fuxe, K Weissbach, H., Udenfriend, Lundholm, L. 491, 530 870,887 S.814,840 - Mohme-Lundholm, E., Ljunggren, L., see Bertler, A. - Weissbach, H., Udenfriend, Svedmyr, N. 453 147,172 S. 189, 226, 619, 656, 853, - see Bevitz, A. 409, 443 - see Falck, B. 147,176 891 Luppa, H., Weiss, J., Feustel, Lloyd, D. P. C. 663, 685, 699, - see Govier, W. C. 423, 448 G.114,179 713,721 - see Horwitz, D. 850, 889 Luse, S. A. 466, 530, 919, 929 Lloyd, K., Hornykiewicz, O. - see Jequier, E. 879,890 - Blank, W., Mettler, F. A. 854, 867, 868, 891 - see Sjoerdsma, A. 189, 228, 865,891 Locke, M., Collins, J. V. 601, 866,896 - Harris, B. 466, 530 613 - see Spector, S. 189, 228 Luyckx, A. S., Lefebvre, P. J. Lodoen, F. V., see Van Orden, - see Udenfriend, S. 85,109 422,453 III, L. S. 786, 787, 812 - see Weissbach, H. 191,230, - see Lefebvre, P. J. 915, 929 Loffelholz, K. 588, 613, 769, 619,660 Lycke, E., Roos, B.-E. 847, 770,771, 772, 773, 775, 782, - see Yamori, Y. 854, 899 870,891 809 Lowenstein, W. R., see Hutter, Lydon, R. J., see Kosterlitz, H. - Lindmar, R., Muscholl, E. O. F. 800, 801, 808 W. 792, 793, 794, 795,809 706,721,741,759 Lowry, o. H., see Harkonen, Lyman, C. P., see Drask06zy, - Muscholl, E. 584, 613, 706, M. H. 662, 719 P. R. 119, 159, 170,174 722,768,769,771,772,781, - see Passoneau, J. V. 402, Lyman, F. L. 845, 891 809,810 455 - see Kilbinger, H. 624, 626, Lucchesi, B. R., Whitsitt, L. S., Maas, J. W., see Colburn, R. 633,634,637,642,643,648, Stickney, J. I. 314, 333 W.250,263 649,650,655 Luco,J. V.800,810 Mac, K., see Sawyer, M. E. 813, - see Lindmar, R. 357, 359, Lucy, J. A. 593, 613 841 588,590,613,706,721,768, - see Howell, J. I. 593, 611 Macadam, R. F. 923, 929 771,772,773,809 Ludden, C. T., see Stone, C. A. Macdougall, J. D., see Coup• Loewenstein, W. R. 564, 613 344,361,468,536,646,647, land, R. E. 22, 25, 30, 31, - see Kanno, Y. 564, 611 659, 823, 827, 842 41,232,263 Loewi, O. 1, 2, 14, 114, 179, - see Torchiana, M. L. 635, MacDougall, L., see Perry, T. 232, 266, 762, 809 659 L. 851, 893 - see Frohlich, A. 336, 358 Ludolph, H.-J., see Rafael, J. Macedo, C., see Antunes, J. L. Logemann, G., see Hippius, H. 412, 415, 456 862,881 861,889 Luduena, F. P., see Lands, A. - see Damasio, A. R. 865, Loizou, L. A. 873, 891 M. 286, 320, 321, 323, 324, 886 Loken, S. C., see Fain, J. N. 325,329,333 Macgregor, A. R., see West, G. 384,385,447 Liidtke, K, see Holtz, P. 2, 14, B. 22, 44, 123,185 Lomax, P., Foster, R. S., Kirk• 187,224,619,654,848,852, Machado, A. B. M. 48, 53, 56, patrick, W. E. 481, 482, 864,889 75 530 Luft, R., see Euler, u.S. von Machlin, L. J., see Hertelendy, Longo, V. G., Silvestrini, B. 202, 222, 270, 280 F. 422, 449 476,530 Lugovoy, J. K., see Natel80n, - see Horino, M. 422, 450 Lorand, L., see Rabinowitz, M. S.112,181 Machne, X., see Stoney, S. D. 401,456 Lum, B. K. B., see Biel, J. H. 664, 665, 668, 669, 724 Lorente de N6, R., Laporte, Y. 814,836 Machova, J., Boska, D. 695, 685,690,722 - see Somani, P. 314, 334 697,701,708,709,710,722 - see Laporte, Y. 676, 677, Lund, A. 111, 112, 121, 179, Macht, D.I., see Abel, J. J.1l4, 678,682,688,690,721 202,203,226 171 - see Marrazzi, A. S. 692, 722 - M0ller, K O. 911, 929 MacIntosh, F. C., see Birks, R. Lorimier, A. de, Bragg, U., Lund, S., see Jankowska, E. 765, 788, 803 Linden, G. 917, 929 518,528 Mackay, D. 288, 333 Author Index 977

MacKenna, B. R. 200, 202, 217, Maitre, L. 191, 226, 501, 507, Malmfors, T., v. Euler, U. S. 226 619,627,637,656 202,226 - see Gillespie, J. S. 210, 223, - Staehelin, M. 188, 189, 218, - Sachs,C. 814,815, 817, 826, 763,807 226,619,623,625,626,627, 827,831,840 Maclaghan, N. F., Wilkinson, 636, 637, 647, 656 - see Corrodi, H. 190, 221 J. H. 270, 281 - see Brunner, H. 637, 646, - see Fuxe, K. 499, 525 MacLeod, J. J. R., see Fulk, M. 647,648,652 - see Haggendal, J. 121, 157, E. 123,176 - see Maier, R. 626, 656 177, 571, 610, 634, 654 Macmillan, W. H. 211, 226 - see Muscholl, E. 188, 205, - see Hamberger, B. 199,209, - Rand, M. J. 169, 179 227,572,613,619,623,627, 224, 240, 264, 622, 654 Madison, L. L., Seyffert, W. A., 631,633,634,636,637,647, - see Hillarp, N.-A. 240, 265 jr., Unger, R. H. Barker, B. 657 - see Jonsson, G. 203, 225 422,453 Maj, J., Langwinski, R. 341, Maltbie, M., see Namm, D. H. - see Seyffert, W. A., jr. 422, 360 393, 394, 395, 396, 398, 455 458 - Przegalinski, E. 504, 530 Malvaldi, G., Mencacci, P., Maeda, T., Wegmann, R. 857, -- Wielosz, M. 504, 530 Viola-Magni, M. P. 30, 43 891 - Vetulani, J. 503, 504, 530 Manara, L., Aigeri, S., Sestini, Maengwyn-Davies, G. D., Kop- Majer, J. R., see Boulton, A. M. G. 500, 531 panyi, T. 354, 360 A. 850, 851, 884 Mancini, G., Frontali, N. 54, - see Pruss, T. P. 658 Makar, H., see Fleming, P. 861, 64, 75, 101, 107 - see Wurzel, M. 314, 335 862,887 Mandell, A. J., Spooner, C. E., Manni, H. F. K., see Hempel, Makinnen, E. 0., see Hopsu, Winters, W. D., Cruikshank, K. 123, 177, 233, 257, 264, V. K. 48,75 M., Sabbot, I. M. 501, 531 565,610 Makman, M. H., Sutherland, - see Spooner, C. E. 465, 512, Marki, F., Axelrod, J. J., Wit• E. W.367,368,453 536 kop, B. 110, 115, 179 Malaisse, W. J., Malaisse-La• Mandell, S., see Stellar, S. 861, Magnall, D., see Banks, P. 602, gae, F. 421, 453 865,897 606 -- Mayhew, D. 420, 421, Manganiello, V., see Murad, F. Magni, F., see Bagnoli, P. 109 453 381,390,455 Magnusson, J., Rosengren, E. -- Wright, P. H., Ashmore, Manger, W. M., Bessis, M. 871, 119,154,179 J.421,422,453 891 Magnusson, T., see Anden, N.• - see Malaisse-Lagae, F. 421, - Wakim, K. G., Bollman, J. E. 206, 219, 495, 498, 519, 453 L. 120,180 625,637,644,652,813,816, - see Williamson, J. R. 371, Manley, E. S., Lawson, J. W. 828,835,865,866,872,874, 373,374,462 299,333 875,881 Malaisse-Lagae, F., Mahy, M., Mann, J. D., see Axelrod, J. - see Bertler, A. 498, 520 Malaisse, W. J. 420, 421, 912,924 - see Carlsson, A. 5, 13, 495, 453 Mann, M., see Butterworth, K. 496, 498, 504, 505, 517, - see Malaisse, W. J. 421, 422, R. 30, 40, 122, 173, 233, 522 453 263 Magoun, H. W., see Ward, A. Malamed, S., Poisner, A. M., - see Callingham, B. A. 30, 40 A., jr. 846, 898 Trifar6, J. M., Douglas, W. Mann, S., see Hebb, C. 125,177 Mahaux, J. E., Schaepdryver, W. 559, 596, 597, 613 Mann, S. P., see Akester, A. R. . A. F. de, Verniory, A., En• Malamud, D. 423, 426, 453 117,171 derle, J., Smets, W., Rein• - Baserga, R. 425, 426, 453 - see Everett, S. D. 117,176 hold, H., Rood, M. de, Malcolm, J. L., see Feldberg, Mannarino, E., Kirshner, N., Meunier, A. 912, 929 W.493,525 Nashold, B. S. 467, 469, Maher, F. T., see Cremer, G. M. Maldonado, M. C., see Albores• 504,505,531 915,925 Saavedra, J. 909, 924 - see Nashold, B. S., 494, 533 - see Gifford, R. W. 900, 926 Malik, K. U. 651, 656 Manocha, S. L., Shanta, T. R. - see Sheps, S. G. 911, 912, - Ling, G. M. 764, 773, 781, 662, 722 914, 915, 931 810 Manshardt, J., Wurtman, R. J. Mahoney, E. M., Friend, O. G., - Muscholl, E. 647, 651, 656 119,180 Dexter, L., Harrison, H. - see Burn, J. H. 767, 804 Mansour, T. E. 394, 453 912,929 Maling, H. M., Highman, B., Mantegazza, P., see Clementi, Mahy, M., see Malaisse-Lagae, Spector, S. 272, 281, 505, F.52,58,60,73,778,805 F. 421, 453 530 Mantegazzini, P., Glasser, A. Maickel, R. P., Beaven, M. A., - see Shore, P. A. 159, 169, 496,531 Brodie, B. B. 349, 360 183 - Poeck, K., Santibaiiez, H. - Matussek, N., Stern, D. N., - see Stern, D. N. 814, 842 G. 477, 531 Brodie, B. B. 814, 840 Mallette, L. E., Exton, J. H., - see Dagirmanjian, R. 495, - see Mayer, S. E., 465, 531 Park, C. R. 372, 453 496,523 - see Paoletti, R. 170,181 Malmejac, J. 783, 810 Manukhin, B. N., Pustovoito• Maier, R., Maitre, L., Staehe• Malmfors, T. 121,179,226,570, va, Z. E., Vyaz'mina, N. M. lin, M. 626, 656 571, 613, 621, 622, 656 117,143,180 62 Hdb. expo PharmakoJ., Vol. XXXIII 978 Author Index

Marche, C., see Laumonier, R. Marrazzi, R. N., see Marrazzi, Matsuoka, M., Ishii, S., Shi· 909,928 A. S. 810 mizu, N., Imaizumi, R. 61, Marche, J., see Laumonier, R. Marsden, C. A., Kerkut, G. A. 76 909,928 81, 82, 89, 90, 91, 94, 96, - Yoshida, H., Imaizumi, R. MarcheselIi, W., see Allegra, F. 107 118, 148, 180, 507, 531 25,39 Marsden, C. D., Foley, T. H., - see Ishii, S. 61, 75 Marchesi, V. T., see Woodin, A. Owen, D. A. L., McAllister, Matthews, E. K. 585, 601, 613 M. 584, 617 R. G. 798, 810 - Saffran,M.585,613 Marechal, L. R., see Torres, H. - Meadows, J. C. 798, 810 Matthews, J., see Lewis, G. P. N. 404, 460 - see Foley, T. H. 494, 525 387,453 Margolis, F. L., Roffi, J., Jost, - see Owen, D. A. L. 494, 533, Matthews, M. R., Nash, J. R. A. 903, 929 798,811 G. 786, 810 - see Roffi, J. 32, 44 Marsden, D. 857, 892 - Raisman, G. 22, 39, 43, 70, Margolius, H. S., see Sugarman, Marsden, H. B. 917, 929 76, 784, 786, 787, 810 S.R.646,648,651,659 Marshall, P. B., see Hunter, R. Matthews, R. J. 682, 722, 783, Margossian, S. S., see McCarl, B. 22, 42, 902, 927 810 R. L. 398, 454 Marshall, R. J., see Farmer, J. - Roberts, B. J. 710, 722 Marin, 0., see Mena, 1. 847, 892 B. 324, 331 Matthews, W. S., see Brown, H. Marinetti, G. V., Ray, T. K., Marteau, R., see Boudin, G. D. 392, 443 Tomasi, V. 368, 377, 382, 867,884 Matthies, H., see Popov, N. 453 Martin, A. P., Baserga, R. 426, U8, 149, 181 Marini-Bettolo, G. B., see Levi• 453 Matthieu, P., Revol, L. 857, Montalcini, R. 819, 840 Martin, D., jr., see Tomkins, G. 892 Markham, C. H. 861, 892 M. 375, 460 Matthysse, S., see Wurtman, R. - Treciokas, 1., Ansel, R. D. Martin, D. B., Carter, J. R., jr. J.874,899 863,892 384,454 Matussek, N., Benkert, 0., - see Ansel, R. D. 863, 865, Martin, W. R., Eades, C. G. Schneider, K., Otten, H., 881 515,517,531 Pohlmeier, H. 862, 892 Marks, B. H., see Samorajski, Maskrey, M., see Bligh, J. 487, - see Halaris, A. 61, 74 T. 198, 199,211,228 520 - see Maickel, R. P. 814, 840 - see Vernikos-DanelIis, J. Mason, D. F. J. 695, 696,722 Matz, L. R., Skinner, S. L. 25, 435,461 Mason, G. A., Hart-Mercer, J., 43 Markus, H. B., Ball, E. G. 385, Millar, E. J., Strang, J. 917, Mauritzen, K., see Gjessing, L. 453 920,929 R. 921, 926 Marley, E. 337, 343, 344, 346, Mason, H. S., see West, E. S. Mawdsley, C. 861, 865, 869, 354,360,474,531 363,461 873,892 - Key, B. J. 471, 474, 475, Mason, J. W., see Kris, A. O. Maxwell, D. R., Palmer, H. T. 476,477,531 422,452 500,531 - Morse, W. H. 480, 509, 531 Masoro, E. J., Rowell, L. B., Maxwell, R. A., Eckhardt, S. - Paton, W. D. M. 240, 266, McDonald, R. M. 454 B., Wastila, W. B. 130, 169, 479,531 --- Steiert, B. 404, 454 180 - Prout, G. 1. 34, 43, 479, 531 Masri, M. S., Booth, A. N., De• - Plummer, A. J., Povalski, - Stephenson, J. D. 471, 474, Eds, F. 857, 892 H., Schneider, F., Coombs, 475,485,488,489,491,495, - Robbins, D. J., Emerson, H. 354, 360, 727, 760 506,508,510,512,513,515, O. H., DeEds, F. 857, 892 - Povalski, H., Plummer, A. 516, 531, 873, 892 Masse, G., see Faivre, G. 911, J. 337,360 - Vane, J. R. 515, 531 926 - Wastila, W. B., Eckhardt, - see Allen, D. J. 484, 485, Mastrolia, L., see Coupland, R. S.B.354,360, 737, 760 491,492,493,509,518 E. 27, 39, 41 - see Trendelenburg, U. 307, - see Blackwell, B. 508, 520 Masuoka, D., see Carlsson, A. 327,334,339,340,342,350, - see Dewhurst, W. G. 464, 653 361, 737, 738, 744, 746, 761 471,474,475,496,497,507, Masuoko, D. T., Alcaraz, A., May, C., see Patil, P. N. 315, 512,513,524 Hanson, E. 626, 656 334 - see Grunden, L. R. 470, 471, Mata, R. 0., see Spector, S. Maycock, W. D'A., Heslop, T. 472,474,485,512,527 501,536 S.34,43 - see Key, B. J. 464, 471, 474, Matlina, E. Sch., Rachmanova, Mayer, K., see Hirschmann, J. 475,485,512,529,873,890 T. B. 123, 179 869,889 Maronde, R., see De Quattro, Matschinsky, F. M., see Brek• Mayer, S. E. 10, 14, 319, 333, V. 194,222 kenridge, B. MeL. 401, 402, 393,396,398,399,440,454 Marques, M., Serrano, L. 142, 443 - Maickel, R. P., Brodie, B. 180 Matsuda, Y. 472, 508, 531 B. 465, 531 Marrazzi, A. S. 682, 722, 783, - see Toda, N. 494, 495, 536 - Namm, D. H., Rice, L. 395, 810 Matsumura, R., see Akabane, 454 - Lorente de N6, R. 692, 722 J.587,605 - Williams, B. J., Smith, J. - Marrazzi, R. N. 810 Matsuoka, M. 504, 531 M. 399, 454 Author Index 979

Mayer, S. E., see Hardman, McCullough, W. S., see Ward, McKendrick, T., Edwards, R. J. G. 737, 758 A. A., jr. 846, 898 W. H. 920, 929 - see Namm, D. H. 392, 393, McCurdy, R. L., Prange, jr., A. McKenna, O. C., Angelakos, E. 394,395,396,398,455 L., Lipton, M. A., Cochrane, T. 126, 161, 180 - see Williams, B. J. 393, 401, C. M. 646, 656 McKereghan, M. R., see Gold• 461 McDonald, R. H., see McNay, stein, M. 189, 193,201,223, Mayfield, E. D., jr., Ghidoni, J. L. 854,891 503,506,526,624,654,814, J. J., Bresnick, E., Stanton, McDonald, R. M., see Masoro, 838 H. C. 425, 426, 454 E. J. 404, 454 McKey, R., see Tamer, A. 848, Mayhew, D., see Malaisse, W. McDougal, M. D., West, G. B. 897 J.420,421,453 792,810 McKinney, T. D., Baldwin, D. Mayhew, D. A.; Wright, P. H., McDowell, F. H. 862,863,865, M., Giles, R. H., jr. 122,180 Ashmore, J. 419, 454 891 McLain, P. L., see Dhalla, N. S. Maynard, D. M. 100, 107 - Lee, J. E., Swift, T., Sweet, 398,446 - Welsh, J. H. 99, 107 R. D., Ogsbury, J. S., Kess• McLean, J. R., Burnstock, G. Maynert, E. W., Levi, R. 119, ler, J. T. 861, 891 115,116, 142,180 180 - see Barbeau, A. 845, 882 - see Dougan, D. F. H. 95,106 Mayor, D., see Banks, P. 53, 60, McElroy, W. T., jr., see Spitzer, - see Hokfelt, B. 122, 177, 72,217,220,250,262,602, J.J.373,459 233,234,265 605,606 McEwen, C. M. 7, 8, 14 McLeish, W. A., see Huang, - see Kapeller, K. 53, 60, 71, McFarland, H., see Vogel, W. S. N. 901, 909, 927 75,602,826,839 H. 853, 854, 898 McLennan, H. 515, 517, 530, Mazeaud, M. 114, 136, 180 McFarlane,J. E., see Furneaux, 689,722 Mazurkiewicz-Kwilecki, I. M. P.J. S. 84, 99, 106 - Pascoe, J. E. 688, 722 299, 314, 316, 333 McGeer, E. G., McGeer, P. L. - see Weir, M. C. L. 783, 784, McAfee, R. D. 434, 454 119,154,180 791,812 McAllister, R. G., see Marsden, - see McGeer, P. L. 150, 180, McManus, J. M., see Moore, P. C. D. 798, 810 495, 497, 498, 530 F. 406, 454 McAuliff, J. P., see Arnold, A. - see Peters, D. A. V. 848,893 McMillan, A., see Armstrong, 320,321,330,387,440,441 - see Wada, J. A. 154, 184, M. D. 6, 11, 193, 219, 270, - see Lands, A. M. 286, 320, 470,479,514,537 272,279,848,881,912,924 321,324,325,329,333 McGeer, P. L., Boulding, J. E., - see Shaw, K. N. F. 270, 281, McCann, D. S., Mitchell, J. G., Gibson, W. C., Foulkes, R. 874,896 Keech, M. K., Boyle, A. J. G. 860, 861, 867, 868, 869, McMillan, M. 905, 912, 929 876,891 874,891 McNay, J. L., McDonald, R. H., - see Honos, E. 876, 889 - McGeer, E. G., Wada, J. A. Goldberg, L. I. 854, 891 McCann, S. M., see Smith, R. 150,180,495,497,498,530 - see Goldberg, L. I. 863, 887 W.489,535 - Zeldowicz, L. R., 860, 891 - see Yeh, B. K. 854, 899 McCarl, R. L., Margossian,S.S., - see Bagchi, S. P. 195,220 McNeill, J. H., Brody, T. M. Jackman, L. M., Webb, R. - see McGeer, E. G. 119, 154, 737,739,760 L. 398, 454 180 - see Brody, T. M. 319, 330, McCarthy, L. E., Borison, H. L. - see Peters, D. A. V. 848, 893 406,440,443 466,530 - see Wada, J. A. 470, 479, - see Commarato, M. A. 337, McConbrey, A., see Boura, A. 514,537 338,358 L. A. 776, 803 McGrath, W. R., Ketteler, H. McNutt, N. S., see Fawcett, D. McCook, R. D., Peiss, C. N., J.501,530 W.397,447 Randall, W. C. 488, 530 - see Tsai, T. H. 341, 362, Mead, A. R., see Shore, P. A. McCormick, W. F., see Nibbe• 834,843 272,281 link, D. W. 901, 930 McGregor, D. D. 767, 810 Meadows, J. C., see Marsden, McCormick, W. G., see Haley, McGuire, L. B., Fox, L. M. C. D. 798, 810 T.J.470,471,476,527 912,929 Meaney, T. F., Buonocore, E. McCoullogh, H. N., see Varma, McHugh, B. P., see Athos, W. 913,929 D. R. 738, 739, 761 J.915,924 Von Mecklenburg, C., see Bert• McCubbin, J. W., Green, J. H., McIlwain, H., see Kakiuchi, H. ler, A. 114, 136, 172 Salmoiraghi, G. C., Page, I. 427,451 - see Dahl, E. 17,41,82,83, H. 709, 722 McInnes, I., see Nayler, W. G. 86,87,91,92,93,94,95,96, - Kaneko, Y., Page, I. H. 396,455 106 494,495,530 McIntosh, D. A. D., see Scales, - see Falck, B. 126, 161, 176 - see Kaneko, Y. 494, 511, B. 398, 421, 458 Medes, G. 852, 892 529 McIsaac, R. J. 783, 810 Meester, W. D., Hardman, H. - see Page, I. H. 708, 723 - see Iorio, L. C. 709, 720 F. 3'99, 454 McCulloch, M. W., see Cairn• - see Kayaalp, S. O. 584, 611, Meier, M., see Brunner, H. 637, cross, K. D. 783, 805 612, 711, 720 646, 647, 648, 652 McCullough, J., see Cervoni, P. - see Norberg, K.-A. 662, 682, Meisch, J.-J., see Carlsson, A. 726,756 723 498,522,624,653 62· 980 Author Index

Meisler, J., see Rabinowitz, M. Merrillees, N. C. R., see Bennett, Miledi, R. 689, 722, 834, 840 401,456 M. R. 665, 715 - see Katz, R 589, 611, 692, Meldolesi, J., see De Virgiliis, Merritt, J. H., Schultz, E. J. 693, 720 G. 563, 608 192,226 - see Krnjevie, K. 800, 809 Mellander, S., see Celander, O. -- Wykes, A. A. 192, 226 Miles, R. M. 900, 901, 929 271,280 Mersmann, H. J., Segal, H. L. Milgram, E., see Wells, H. 425, Melmon, K., see Spector, S. 370,454 461 189,228 Mertens-Strythagen, J., see Milhaud, G., Glowinski, J. 467, Melson, G. L., Chase, L. R., De Schryver, C. 159, 170, 532 Aurbach, G. D. 433, 454 182 Millar, E. J., see Mason, G. A. Meltzer, S. J. 832, 840 Merton, P. A. 800, 810 917,920,929 - Auer, C. M. 832, 840 Messeloff, C. R., see Sacks, O. Millar, R. A., Benfey, B. G. Melville, K. I. 2, 14 W. 861, 865,894 132,180 - Johnson, M. C.494, 531 Messiha, F. S., Agallianos, D., Millard, R. W., see Angelakos, - see Gagnon, D. J. 494, 511, Clower, C. 855,892 E. T. 115, 137, 139, 140, 525 - see Gey, K. F. 867, 887 160,171 - see Share, N. N. 494, 535 Mestyan, G., see Dawes, G. S. Miller, see Coons 482 Mena, I., Court, J., Fuenzalida, 485,491,523 Miller, H. I., see Issekutz, R, S., Papavasiliou, P. S., Cot• van Meter, W. G., see Costa, E. jr. 404, 450 zias, G. C. 861, 865, 880, 892 496,523 Miller, J. W. 327, 333 - Marin, 0., Fuenzalida, S., Mettler, F. A., see Luse, S. A. - see Cha, K.-S. 127, 164, 173 Cotzias, G. C. 847, 892 865,891 - see Giles, R. E. 164, 176, - see Cotzias, G. C. 861, 863, Metzel, E., Weinmann, D., Rie• 506,526,750,758 885 chert, T. 854, 856, 858, 892 - see Green, R. D. 127, 177 Menahan, L. A., Wieland, O. Metzner, W. R. T., see Leim• - see Rudzik, A. D. 127,182 372,374,454 dorfer, A. 469, 470, 471, - see Spratto, G. R. 127,183 - see Hepp, D. 382, 449 530 Miller, L. L. 372, 375, 454 Mencacci, P., see Malvaldi, G. Meunier, A., see Mahaux, J. E. Miller, N. E. 482, 488, 491, 532 30,43 912,929 - Gottesman, K. S., Emery, Mendell, J. R., Chase, T. N., Meyer, H. 464, 532 N. 488, 489, 532 Engel, W. K. 846, 860, 862, - see Levi-Montalcini, R. 818, - see Slangen, J. L. 490, 510, 892 840 535 Mendez, R., see Kabela, E. 318, Miller, R. E., see Kris, A. O. Meyerhoff, J. L., see Snyder, S. 422,452 332 H. 854, 865, 897 Mendlowitz, Wolf, L., Miller, W., Fraumeni, J. F., M., R. Meythaler, Mitznegg, R. R, see Hill, J. A. 917, 929 Gitlow, S. E. 845, 892 P.406,454 - see Gitlow, S. E. 912, 926 Milne, M. D., see Asatoor, A. Meng, H. C., see Butcher, R. W. Mical, R. S., see Kamberi, I. A. M. 877, 881 381,444 866,890 Mims, C. A. 467, 532 Menkin, V., see Cannon, W. B. Michaelson, I. A. 54, 58, 76 Minemura, T., Crofford, O. R 813,830.836 - Taylor, P. W., Richardson, 385,454 Menon, M. K., Dandiya, P. C., K. C., Titus, E. 58, 76 Minnis, R., see Daly, J. W. 857, Bapna,J. S.502,531 - see Sjoqvist, F. 56,77,821, 886 Menon, T., see Sutherland, E. 842 Minz, B., see Feldberg, W. 478, W.401,460 - see Whittaker, V. P. 37, 44, 525,584,609 Mensendiek, S. R., see Furch• 617 Mirkin, B. L., Brown, D. M., gott, R. F. 271, 280, 742, Michelakis, A. M., Robertson, Ulstrom, R. A. 131, 180 752,757 D. 864, 892 - Cervoni, P. 766, 810 Mercier, D., see Shealy, C. N. Michell, H., see Carlson, L. A. Mirolli, M. 96, 108 870,896 387,444 - Welsh, J. H. 96, 108 Merimee, T. J., see Edgar, P. Mi6ie, R., Kicic, M., Adanja, S. Mishkin, M., see Robinson, B. 421,446 902,929 W.489,534 Merlino, N. S., see Blecher, M. Mickle, D., see Johnson, G. E. Missala, K., see Lancaster, G. 382,390,443 625,632,655 847,868,891 Merlis, S., see Yaryura-Tobias, Middleton, S., see Cabrera, R. - see Sourkes, T. L. 867, 897 J. A. 862, 899 764,805 Misu, Y., see Kirpekar, S. M. Merlo, A. R, Izquierdo, I. 507, - see Hoffmann, F. 764, 808 568,588, 612, 693, 720, 781, 531,532 Midtvedt, T., see Scheline, R. 782,808 - see Izquierdo, I. 507, 528 R. 877. 895 Misugi, K., Misugi, N., New• Merrill, S., Chrojka, V. E., Ber• - see Strandberg, K. 165, 184 ton.W.A.909,919.920,929 kowitz, G. M., Texter, E. C. Miele, E. 584, 613 Misugi, N., see Misugi, K. 909, 915,929 - Rubin, R. P. 589, 613 919,920,929 Merrillees, N. C. R. 53, 71, 76 - see Jaanus, S. D. 589, 611 Mitchell, J. G., see McCann, D. - Burnstock, G., Holman, M. - see Rubin, R. P. 584, 589, S. 876, 891 E. 729, 731, 760 615 Mitchell, R. M. 30, 43 Author Index 981

Mitoma, C., Posner, H. S., Bog• Mondon, C. E., see Burton, Morgan, J. P., Preziosi, T. J., danski, D. F., Udenfriend, S. D. 376, 444 Bianchine, J. R., 862, 892 S.878,892 - see Mortimore, G. E. 454 - Spiegel, H. E., Hersey, R. Mitznegg, P., Heim, F., Mey• Mones, R. J., Elizan, T. S., Sie• M., Calimlim, L. R., Bian• thaler, B. 406, 454 gel, G. J. 861, 862, 866, 869, chine, J. R. 871, 874, 876, Miyagi, S., see Patil, P. N.315, 892 892 334 Monnier, M. 496, 531 - see Rivera-Calimlim, L. 871, Miyahara, M. 125, 160, 180 - Tissot, R. 496, 532 894 Miyamoto, E., Kuo, J. F., Monro, A. F., see Robinson, R. Morgane, P. J. 489, 532 Greengard, P. 428, 454 34,44 - see Hernandez-Pe6n, R.489, Miyamoto, S., see Abood, L. G. Monroe, B. G. 67, 76 528 256,261 Monroy, E., see Costero, I. 560, Morimoto, M., see Imura, H. Miyazawa, T., see Akabane, J. 607 435,450 587,605 Montagu, K. A. 112, 118, 147, Morin, R. D., see Smythies, J. Mjones, H. 846, 892 159,166,180,188,226,796, R. 866, 897 Modder, G. P., see Van den 800,810 Mornex, R., see Hermann, H. Bergh, S. G. 415, 460 Montagu, K. R. 4, 14 861,889,900,901,902,903, Modolell, J. B., Moore, R. O. Montanari, R., Costa, E., Bea• 904,913,927 382,454 ven, M. A., Brodie, B. B. Morpurgo, C., see Pscheidt, G. Modonesi, G., see Muratori, G. 196,226 R. 504, 505, 534 23,43 Montplaisir, J., Barbeau, A. Morris, L., see Smith, R. A. Moller, H. 25, 43 851,892 919,932 Moellman, H., see Knoche, H. Moore, A. E., see Clark, A. C. Morrison, J. M., jr., Fleming, 113, 130,179 L. 920, 921,925 W. W.833,834,840 Moerman, E. J., see Amery, A. Moore, G. E., O'Donnell, S. R. - see Hanig, J. F. 873, 888 627,652,916,924 307,310,333 Morse, W. H., Herrnstein, R. J. - see De Potter, W. P. 214, Moore, K. E. 502, 504, 532 480,532 217,221,574,576,578,588, - Lariviere, E. W. 119, 180 - see Marley, E. 480, 509, 590,608 - Rech, R. H. 502, 506, 532 531 Moerman, E. H., see Smith, A. - Wright, P. F., Bert, J. K. - see Wurtman, R. J. 479, D. 557, 575, 576, 578, 579, 502,532 509,514,537 580, 581, 588, 616 - see Carr, L. A. 466, 467, Mortati, F. S., see Golden, R. Moffett, R. B., Hanze, A. R., 468,469,502,522 L. 868, 887 Seay, P. H. 506, 532 - see Dominic, J. A. 503, 524 Mortimore, G. E., Mondon, C. Mogabgab, W. J., see Beltran, Moore, P. F., Iorio, L. C., E.454 G.924 McManus, J. M. 406,454 - see Glinsmann, W. H. 372, Mohammed, S., Gaffney, T. E., Moore, R. E., Underwood, M. 376,448 Yard, A. C., Gomez, H. 647, C.485,491,532 - see Mondon, C. E. 372, 373, 656 Moore, R. M., see Cannon, W. 454 - see Sugarman, S. R. 646, B. 813, 830, 836 Morton, I. K. M., see Jenkin• 648, 651, 659 Moore, R. 0., see Modolell, J. son, D. H. 298, 319, 332, Mohme-Lundholm, E. 405, 454 B. 382, 454 795,808 - see Andersson, R. G. G. 406, Moore, R. Y., see Wurtman, R. Mosal, N. C., see Govier, W. C. 441 J. 120,185 298,332 - see Bevitz, A. 409, 443 Moorhead, E. L., Caldwell, J. Moses, S. G., see Robins, E. - see Lundholm, L. 453 R., Kelly, A. R., Morales, 854,894 Mohs, V., see Degkwitz, R. 860, A. R. 900, 901, 929 Mosinger, B., Kujalova, V. 382, 886 Moorhead, M., see Welsh, J. H. 454 Moir, A. T. B., Ashcroft, G. W., 87,89,90,99,109 - Vaughan, M. 381, 382, 383, Crawford, T. B. B., Eccle• Moppert, J. 596, 613 454 ston, D., Guldberg, H. C. Morales, A. R. j see Moorhead, Most, A. S., see Henderson, A. 859,872,892 E. L. 900, 901, 929 H. 398, 449 Molina-Negro, P., see Papeschi, Moran, J., see Belleau, B. 7, 12 Moulins, M., see Chanussot, B. R. 859, 893 Moran, N. C. 286, 320, 333 101,105 Molinoff, P. 826, 875, 892 - Perkins, M. E. 285, 333, Moxness, K. E., see Cremer, G. - Axelrod, J. 629, 656, 814, 814,840 M.915,925 816, 822, 840, 879, 892 - see Reddy, V. 318, 334 Moyer, K. E., Bunnell, B. N. - Landsberg, L., Axelrod, J. Moreau, A., see Cordeau, J. P. 479,532 629,656 476,523 Mrastolina, Coupland, R. E. M011er, K. 0., see Lund, A. 911, Morgan, C. D., Ruthven, C. R. 34 929 J., Sandler, M. 875, 892 Miihlbachova, E., see Lincova, Molnar, G. D., see Cremer, G. Morgan, H. E., Parmeggiani, D. 387, 453 M.915,925 A. 399, 454 Miiller, H. K., see Grobecker, Mondon, C. E., Mortimore, G. - see Robison, G. A. 392, H. 115, 140, 177, 619, 628, E. 372, 373, 454 393,395,396,457 637,6/H 982 Author Index

Miiller, 0., Bee Ratzenhofer, M. Murphy, G. F., Robinson, D., Muscholl, E., see Kilbinger, II. 31, 43, 600, 615, 909, 911, Sharman, D. F. 873, 893 624,626,633,634,637,642, 915,930 - Sourkes, T. L. 227, 636, 658 643,648,649,650,655 Miiller, P. B., see Langemann, - see Barbeau, A. 855, 860, - see Lindmar, R. 202, 209, II. 853, 891, 902, 928 869,879,882 210,211,226,240,266,337, - see Ziegler, W. II. 905, 933 - Bee Drujan, B. D. 121, 170, 338,340,349,355,357,359, Mueller, R. A., Thoenen, II., 174 360,570,588,590,613,621, Axelrod, J. 194, 195, 226, - see Sharman, D. F. 847, 896 622,623,625,627,630,633, 813,814,822,826,830,834, - see Sourkes, T. L. 111, 183, 634, 635, 637, 638, 642, 643, 840, 904, 929 189,191,228,497,536,874, 644,645,647,648,649,650, - see Axelrod, J. 195, 219 878,897,920,921,932 655,656,706,721,728,735, - see Thoenen, II. 194, 229, Musacchia, X. J., Jellinek, M., 736, 739, 740, 759, 768, 771, 235,268,600,616 Cooper, T. 142, 180 772,773,774,809 Miiller-Calgan, II., Sommer, S. Musacchio, J. M. 232, 233, 266 - see Li:iffelholz, K. 584, 613, 848,893 - Bhagat, B., Jackson, C. J., 706,721,722,741,759,768, Muenter, M. D., see Tyee, G. M. Kopin, 1. J. 337, 360, 635, 769, 771, 772, 781, 809, 810 871, 874, 880, 898 656 - see Malik, K. U. 647, 651, Muenzer, J., see Wolfe, S. M. - Fischer, J. E., Kopin, 1. J. 656 423,462 621,625,632,633,656 - see Weber, E. 212,230,622, Muir, T. C., Yonemura, K. 695, - Goldstein, M. 189, 227, 619, 649,660 706, 722 626,656 Muskus, A., see Trendelenburg, - see Crowcroft, P. J. 668, -- Anagnoste, B., Poch, G., U. 301, 334, 648, 659, 832, 674,716 Kopin, 1. J. 503, 532 833,843 - see Gillespie, J. S. 748, 758, - Kopin, 1. J., Snyder, S. 193, Muskus, A. J. 354, 355, 360 828,838 201, 227, 503, 532 - see Crout, J. R. 217, 221, Muirhead, M., IIimms-IIagen, -- Weise, V. K. 201, 227, 338, 358, 468, 502, 523 J. 408, 455 338,352,360,503,532,619, - see Liebman, J. 354, 359 Mulholland, S. G., Atuk, M. 0., 620, 621, 626, 636, 656 - see Pluchino, S. 354, 355, Walzak, M. R. 901, 929 - Weise, V. K., Kopin, 1. J. 360 Mullen, P. E., see Smith, 1. 850, 201,216,227,620,621,626, - see Trendelenburg, U. 337, 896 645,656 341,343,344,345,351,362, Mulligan, R. M. 900, 929 - see Fischer, J. E. 816, 837 737,747, 761 Munkvad, T., see Randrup, A. - see Kopin, 1. J. 205, 208, Myers, R. D. 467, 472, 473, 488, A. 236, 267, 502,534 225,338,352,359,619,621, 489,532 Munoz, C., see Goldstein, L. 626, 629, 633, 642, 646, 655 - Sharpe, L. G. 489, 532 477,508,526 Muscholl, E. 11, 159, 160, 180, - Yaksh, T. L. 481, 482, 484, Munro, A. F. 318, 333 188,190,205,208,209,211, 486,487,490,491,533 Munske, K.,seeSenft,G. 367,458 212,214,227,497,532,572, - see Feldberg, W. 483, 486, Munson, P. L., see Wells, II. 573, 613, 618, 619, 624, 628, 524,525 425,461 632,639,652,657,737,738, - see Sharpe, L. G. 489, 490, Murad, F., Chi, Y.-M., Rail, T. 760, 763, 772, 783, 810, 814, 535 W., Sutherland, E. W. 367, 816, 833, 840, 914, 929 Myhrberg, H. E. 81, 90, 91, 108 371, 392, 396, 399, 455 - Drews, E.-F., Lindmar, R. - see Dahl, E. 82, 83, 86, 87, - Manganiello, V., Vaughan, 633,657 91,92,93,94,95,96,106 M. 381, 390, 455 - Lindmar, R. 621, 648, 657 - see Ehinger, B. 89, 106 - Rail, T. W., Vaughan, M. - Maitre, L. 188, 205, 227, Mylius, E. A., see Berdal, P. 390,404,405,455 572,613,619,623,627,631, 922,923,924 - Vaughan, M. 392, 393, 395, 633, 634, 636, 637, 647, 657 Myrin, S.-O., see Euler, U. S. 455 - Rahn, K. H. 624, 627, 628, von 482,524 - Bee Vaughan, M. 381, 382, 642,657 384,386,460 -- Watzka, M. 23, 43, 169, Naess, K., Simes, T. B. 798, Murad, J. E., Shore, P. A. 622, 180 800,810 656 - Sprenger, E. 351, 360, 621, Nagasaka, M., Bouckaert, J., Muratori, G. 23, 24, 43 625, 637, 644, 646, 648, 657 de Schaepdryver, A. F., - Battaglia, G. 23, 43 - Vogt, M. 39, 43, 124, 156, Heymans, C. 298, 333 -- Modonesi, G. 23, 43 180,498,532,550,613,787, Nagata, N., Rasmussen, II. - Chiarini, C., Battaglia, G. 810 433,455 23,43 - Weber, E. 208, 227, 349, Nagatsu, 1., see Nagatsu, T. Murayama, S., Unna, K. R. 360, 622, 649, 657 904,916,929 706, 722 - see Drews, E.-F. 621, 625, Nagatsu, T., Kuzuya, H., Hi• - see Sanghvi, 1. 705, 723 637,653 daka, H. 557, 613 Murnaghan, M. F. 338, 360 - see Hukovic, S. 211, 212, - Levitt, M., Udenfriend, S. Murphy, D. L., see Goodwin, 225,240,265,586,588,611, 8, 14, 187, 191, 194, 227, F. K. 846, 859, 862, 865, 649, 654, 753, 758, 774, 781, 231,232,234,266,501,533, 871, 872, 874, 875, 888 808,814,839 848, 878, 893, 902, 930 Author Index 983

Nagatau, T., Rust, L. A., De Natelson, S., Lugovoy, J. K., Niemcyzyk, H., see Baust, W. Quattro, V. 126, 161, 167, Pincus, J. B. 112,181 477,520 180,813,816,822,840 Nayler, W. G., McInnes, 1., Niemi, M., Ojala, K. 922, 930 - Van der Schoot, J. B., Le· Chipperfield, D., Carson, V., Nierenstein, M., see Roaf, H. vitt, M., Udenfriend, S. 193, Daile, P. 396, 455 E.17,43 227 Necina, J. 498, 533 Nikodijevic, B., Creveling, C. - Zamamoto, T., Nagatsu, 1. Nedergaard, O. A., Bevan, J. R., Udenfriend, S. 192, 227 904, 916, 929 A. 773, 810 - Daly, J., Creveling, C. R. - see Ayukawa, S. 191, 219 - Westermann, E. 295, 297, 112,134,149,159,181 - see DeQuattro, V. 194, 222 327,334 Nilson, B., see Hillarp, N.-A. - see Udenfriend, S. 194, 229, - see Bevan, J. A. 569, 606 5, 14, 246, 248, 249, 251, 234,269,501,505,537,619, Neff, N. H., Barrett, R. E., 252,257,265,539,592,594, 627,640,660,814,843,850, Costa, E. 58, 76, 848, 893 610 898, 904, 933 - Costa, E. 235, 266, 499, 505, Nilsson, J., see Carlsson, A. 5, Nahas, G. G., see Kypson, J. 533 13, 244, 263, 336, 358, 814, 382,383,452 - Ngai, S. H., Wang, C. T., 836 - see Poyart, C. F. 389, 456 Costa, E. 639, 657 Nilsson, 0., see Fuxe, E. 37, - see Triner, L. 405, 406, 460 - see Costa, E. 632, 641, 653 41,46,61,67,71,74,866,887 Naimark, A., see Havel, R. J. Neil, E., O'Regan, R. G. 24, 43 Ninteman, F. W., see Poschel, 404,449 Nelson, P. G., see Hunt, C. C. B. P. H. 502, 533 Nakajima, K., see Goldstein, 664,668,675,689,720 Nishi, S., Koketsu, K. 664, 668, M. 501, 503, 526 Nestianu, V., see Floru, R. 478, 669,671,673,674,676,677, Nakajima, S., Takahashi, K. 525 683,684,695,722,789,810 686, 722 Newsholme, E. A., see Randle, - Soeda, H., Koketsu, K. Nakama, M., see Takagi, H. P. J. 402, 456 664,674,675,676,683,685, 498,536 Newton, H. F., see Cannon, 'V. 688,690,722 Nakanishi, S., see Akabane, J. B. 813, 830, 836 - see Christ, D. D. 668, 707, 587,605 Newton, W. A., see Misugi, K. 716,789,790,791,805 Nakano, J., Ishii, T., Pyron, 909,919,920,929 - see Koketsu, K. 663, 666, J. T., House, E. C. 385, Ng, K. Y., Chase, T. N., Col• 670,678,683,695,696,720, 455 burn, R. W., Kopin, 1. J. 721 Nakano, T., Tomlinson, N. 872,879,893 Nishida, S., Trotter, J., Sears, 114,136,181 Ngai, S. H., see Costa, E. 632, M. L. 52, 76 Nakao, K., see Kajinuma, H. 641,653 Nishihara, H. 802, 810 422,451 - see Neff, N. H. 639, 657 Nishikawa, T., see Iwata, H. - see Kaneto, A. 422, 451 Niall, M., see Clark, A. C. L. 167,178 Nakatani, S., see Battista, A. 920,921,925 Nishinumani, K., see Sano, 1. F. 847, 882 Nibbelink,D. W.,Peters,B.H., 118, 155, 182 - see Goldstein, M. 847, 863, McCormick, W. F. 901, 930 Noble, E. P., Wurtman, R. J., 874,880,888 Nice, L. B., see Cannon, W. B. Axelrod, J. 466, 499, 533 Namba, J., see Yoshida, H. 800,805 Noda, Y., see Koketau, K. 678, 852,899 Nicholls, J. G. 689, 722 696,721 Namm, D. H., Mayer, S. E. - Baylor, D. A. 686, 722 Noel, J., see Best, J. B. 54, 60, 392,394,395,396,455 Nicholls, M. R., see Judah, J. 72 - Mayer, S. E., Maltbie, M. D. 377, 451 Nomura, J., see Varon, S. 819, 393, 394,395,396,3~8,455 Nichols, C. W., Jacobowitz, D., 843 - see Mayer, S. E. 395, 454 Hottenstein, M. 121, 157, Norberg, K.-A. 662, 723, 787, Nance, S. L., see Thomson, J. 181 796,811 F. 411, 412, 460 Nicholson, W. E., see Abe, K. - Hamberger, B. 216, 227, Nanta, V., see Pekkarinen, A. 434,441 240,266,662,723,787,811 912,930 Nickerson, M. 9, 14, 284, 285, - McIsaac, R. J. 662, 682, 723 Naranjo, C., see Shulgin, A. T. 316, 334, 814, 841 - Olson, L. 129, 181 866,896 - Goodman, L. S. 9, 14 - Ritzen, lL, Ungerstedt, U. Nash, C. W., Costa, E., Brodie, - Hollenberg, N. K. 507, 511, 786,787,811 B. B. 278, 281 533 - Sjaqvist, F. 682, 723, 783, - Wolff, S. A., Ferguson, B. - see Harvey, S. C. 479, 509, 787,811 A. 352, 360 527 - see Almgren, O. 752, 756 Nash, J. R. G., see Matthews, - see Kalsner, S. 274, 278, - see Anden, N.-E. 129, 166, M. R. 786, 810 281,304,332,727,728,738, 171 Nashold, B. S., Mannarino, E., 744, 750, 752, 759 - see Brundin, T. 124,173 Wunderlich, M. 494, 533 - see Stromblad, B. C. R. 197, - see Frontali, N. 100,106 - see Mannarino, E. 467, 469, 198,201,206,229,341,361, - see Hamberger, B. 199,209, 504,505,531 816, 842, 914, 932 224,622,654,662,719,747, Nasmyth, P. A., Andrews, W. Nielsen, S.-O., see Elofsson, R. 758,787,796,807,820,821, H. H. 211, 227 99,100,106 822,830,838 984 Author Index

Nordenfeldt, I. 765, 811 Ostman, J., Efendic, S., Arner, Olsson, R., Roos, B.-E. 846, Nordenstam, H., Wester, P. O. P. 386, 387, 455 860,893 25,43 Oetliker, 0., see Donath, A. Oota, Y., see Kobayashi, H. - see Adams·Ray, J. 24, 39 901,905,912,913,925 67, 75 - see Ostlund, E. 134,181 Ogata, H., see Akabane, J. 587, Oram, F. J., see Hunter, RB. Nordgren, L., see Falck, B.147, 605 22,42,902,927 176 Ogg, J., see Roth, G. M. 901, Orbeli, L. A. 800, 811 Normann, T. C. 563, 584, 613 930 Ord, M. G., see Prusoff, W. H. North, W. G. 136, 139, 181 O'Gorman, L. P., Borud, 0., 249,267 Northrop, G., Parks, R. E., jr. Khan, I. A., Gjessing, L. R. Ordy, J. M., Samovajski, T., 367,371,455 866, 874, 876, 893 Schroeder, D. 160, 181 Northrop, R. B. 99, 108, 316, Ogsbury, J. S., see McDowell, O'Regan, R G., see Neil, E. 24, 334,376,455 F. H. 861, 891 43 Norton, S., see Pirch, J. H. 505, Ohad, I., see Amsterdam, A. Orfei, V., see Vogel, W. H. 854, 533 423,441,589,597,605 898 Nott, M. W., see Bowman, W. Ohi, Y., see Hashimoto, Y. 61, Orloff, J., see Handler, J. S. C. 319, 330, 796, 797, 798, 74 433,434,449 800,802,804 Ohuchi, T., see Oka, M. 239, Ormond, R E., see Kuehl, F. Nourok, D. S. 901, 930 246,248,254,255,256,259, A., jr. 850, 891 Novales, R. R., Davis, W. J. 266,539,542,559,587,591, Oro, L., Wallenberg, L., Rosell, 434,455 595,596,614 S.387,455 Novin, D., see Sommer, S. R. Ojala, K., see Niemi, M. 922, Osborne, N. N., Cottrell, G. A. 489,535 930 82,96,97,108 Nowaczynski, W., see Barbeau, Oka, M., Kajikawa, K., Ohu• - Dando, M. R. 100, 108 A. 864, 882 chi, T., Yoshida, H., Imai• - see Cottrell, G. A. 94, 96, Nukada, T., Sakurai, T., Imai· zumi, R. 239, 246, 248, 254, 106 zumi, R 504, 533 266,542,614 Osher, J. V., see Bevan, J. A. Nyback, H., Borzecki, Z., Sed• - Ohuchi, T., Yoshida, H., 325,330 vall, G. 467,468,499,533 Imaizumi, R. 254, 255, 256, Oshima, T., see Ito, M. 672, - seeSchubert,J.499,500,535 259,267,539, 559, 587, 591, 673,720 Nystedt, T., see Falck, B. 125, 595,596,614 Oskarsson, V. 164,181 128,176 O'Keeffe, R, Sharman, D. F., Osswald, H., see Fiilgraff, G. Vogt, M. 148,154,181,855, 319,331 Oates, J. A., Gillespie, L., 893 Osswald, W., see Garrett, J. Udenfriend, S., Sjoerdsma, Okegawa, T., see Fujiwara, M. 914,926 A. 191, 227, 618, 657 129,166,176 - see Guimaraes, S. 327, 332 - see Gillespie, L. 620, 654 Okros, I., see Pfeiffer, A. K. 61, - see Holtz, P. 337, 359 - see Sjoerdsma, A. 189, 228 76 Ostberg, A., see Geffen, L. B. Obrador, S., Odoriz, J. B. 699, Olbermann, M., see Rahn, K. 60, 74, 543, 602, 603, 609, 723 H. 646, 648, 658 826,838 Obre, A. 799, 811 Olin, J. S., see Shore, P. A. 112, - see Holman, M. E. 719 O'Brien, R. A., see Boullin, D. 183 Ostrom, R J., see Verity, M. A. J. 873, 879,884 Oliver, G., Schafer, E. A. 796, 569,616 Ochi, J., Konishi, M., Yoshi• 811 Osuide, G., see Bowman, W. C. kawa, H. 52, 76 Oliver, I. T., see Holt, P. G. 515,521 Ochs, S., see Sigg, E. 515, 535 375,450 O'Toole, A. G., see Goldberg, O'Connor, W. V., see Arnold, - see Yeung, D. 375, 376, 462 N. D. 428, 448 A. 320, 321, 330 Oliver, N., see Friesen, A. J. D. Otten, H., see Matussek, N. O'Donnell, S. R, see Chahl, L. 394,398,447 862,892 A. 310, 331, 745, 746, 756 Olivereau, M. 18, 43 Outschoorn, A. S., see Craw• - see Moore, G. E. 307, 310, Oliverio, A., Stjarne, L. 194, ford, T. B. B. 111, 112,174 333 227 Overton, E. 464, 533 Odoriz, J. B., see Obrador, S. - see Carpi, A. 814, 837 Overweg, N. I. A., see Triner, 699, 723 Olson, L., see Almgren, O. 752, L. 405, 406, 460 Ostlund, E. 17, 18, 43, 81, 84, 756 Owen, C. A., see Zimon, R. P. 85, 86, 99, 102, lO3, 108, - see Anden, N.-E. 129, 166, 912,933 113, 134, 135, 136, 140, 181 171,865,866,872,874,875, Owen, C. A., jr., see Tyee, G.M. - Bloom, G., Adams-Ray, J., 881 871,874,880,898 Ritzen, M., Siegman, M., - see Hamberger, B. 747, 758 Owen, D. A. A., see Day, M. D. Nordenstam, H., Lishajko, - see Norberg, K.-A. 129, 181 211,221,571,607 F., von Euler, U. S. 134, 181 Olson, M. S., see Williamson, J. Owen, D. A. L., Marsden, C. D. - see Augustinsson, K. B. 134, R. 409, 412, 413, 414, 415, 494, 533, 798, 811 171 462 - see Foley, T. H. 494, 525 - see Bloom, G. 18, 40, 113, Olsson, K., see Andersson, B. - see Marsden, C. D. 798, 810 134,172 484,519 Owen, M. 99 Author Index 985

Owen, W. S., see Goldstein, M. Palm, D. 868, 893 Parker, S. W., Feldman, S. M. 847,850,887 - Langeneckert, W., Holtz, P. 489,533 Owman, C. 206, 227, 428, 455 297,334,648,657 Parkes, J. D., Sharpstone, P., - Rosengren, E., Sjoberg, N.• - see Balzer, H. 190, 220 Williams, R. 862, 893 O. 127, 164,181 - see Fein, J. 647, 653 - Zilkha, K. J., Calver, D. M., - Sjoberg, N.-O. 127, 181 - see Grobecker, H. 587, 590, Knill-Jones, R. P. 869, 893 - see Bertler, A. 133,172,872, 610 - see Godwin-Austen, R. B. 883 - see Holtz, P. 2, 14, 188,224, 870,887 - see Falck, B. 80, 106, 114, 252,258,261,265,353,359, Parkinson, J. 846, 893 115, 133, 140, 176 639,647,652,654,860,864, Parks, R. E., jr., see Northrop, - see Hakanson, R. 133, 165, 867,868,889,900,927 G. 367, 371, 455 177,816,838 Palmer, A. C. 470, 471, 476, 533 Parmeggiani, A., see Morgan, - see Larson, B. 133, 179 Palmer, H. T., see Maxwell, D. H. E. 399, 454 Owman, T., see Baumgarten, R. 500, 531 Parr, J. J., see Campos, H. A. H. G. 126, 163,172,796,803 Palmgren, A., see Johnels, A. 426,444 0ye, I. 394, 395, 398, 399, 455 G.17,42 Parra, A., Schultz, R. B., Fo• - Sutherland, E. W. 10, 14, Panigel, M., see Contractor, S. ley, T. P., jr., Blizzard, R. 433,455 F. 871, 885 M. 435, 455 - see Robison, G. A. 392,393, Panisset, J.-C., see Palaic, D. Partridge, S. M. 7, 14 395,396,457 163,181 Pascoe, J. E. 663, 665, 695, 696, - see Sutherland, E. W. 363, Panke, W., see Rossi, P. 913, 697, 703, 723 460 930 - see Brown, G. L. 688, 689, Ozaki, M., see Goldberg, L. 1. Paoletti, R., Smith, R. L., 690,716 636, 651, 654 Maickel, R. R., Brodie, B. - see McLennan, H. 688, 722 - see Hess, S. M. 497, 528, 636, B. 170,181 PaBio, M., Lj. Savio, V. 686,723 639,654 - see Smith, R. L. 170, 183 Passoneau, J. V., Lowry, O. H. Ozawa, E., Ebashi, S. 393, 394, Papavasiliou, P. S., see Cotzias, 402,455 403,455 G.C.857,860,861,863,864, - see Harkonen, M. H. 662, 719 - Hosoi, K., Ebashi, S. 403, 867, 873, 874, 875, 880, 885 Patel, D. G., see Patil, D. G. 455 - see Mena, 1. 861, 865, 880, 329,334 892 Patetta, M. A., see Caldeyro, R. Paasonen, M. K., Krayer, O. Papeschi, R., Molina-Negro, P., 114,173 336,354,360 Sourkes, T. L., Hardy, J., Patil, P. N. 296, 310, 311, 312, - see Krayer, O. 355, 359 Bertrand, C. 859, 893 323,325,334 Pacha, W., see Salzmann, R. Pappano, A. J., Volle, R. L. - Jacobowitz, D. 347, 351, 313,334,353,361 696,704,723 360,621,657 Paddle, B. M., see Prusinger, - see Takeshige, C. 704, 724 - Lapidus, J. B., Campbell, s. B. 413, 415, 456 - see Volle, R. L. 676, 682, D., Tye,A.344,346,347,352, Page, 1. H., Green, A. A. 111, 705,725 360 181 Paradise, R., see Christian, D. - - Tye, A. 344, 346, 347, - McCubbin, J. W. 708, 723 R. 394, 395, 444 352,360,623,657 - see Kaneko, Y.494,511,529 Pardo, E. G., Cato, J., Gij6n, - Patel, D. G., Krell, R. D. - see McCubbin, J. W. 494, E., Alonso de Florida, F. 329,334 495,530,709,722 783,811 - Tye, A., May, C., Hetey, S., - see PalaUJ, D. 500, 533 Pare, C. M. B., Sandler, M. 862, Miyagi, S. 315, 334 Page, L. B., Jacoby, G. A. 905, 893 - see Buckner, C. K. 323, 331 906,909,913,918,919,921, - Sandler, M., Stacey, R. S. - see Kilbinger, H. 624, 633, 930 854,893 634,637,642,643,648,649, Paimre, M., see Rubin, R. P. - Yeung, D. P. H., Price, K., 650,655 586,615 Stacey, R. S. 856, 893 - see Lapidus, J. B. 302, 333 Pak, C. 202, 227 Parent, A., see Bedard, P. 847, - see Seidehamel, R. J. 746, Pakkenberg, H., Brody, H. 882 747, 760 846,857,893 Parikh, H. M., see Gulati, O. D. - see Swamy, V. C. 649, 659 Palade, G. E. 596, 597, 614 299, 314, 315, 332 - see Tye, A. 346, 351, 362 - see Clementi, F. 564, 607 Park, C. R., see Buschiazzo, H. Paton, D. M. 622, 623, 657 - see Jamieson, J. D. 598, 611 370,393,444 - see Daniel, E. F. 319, 331, Palaic, D., Page, 1. H., Khair• - see Exton, J. H. 368, 370, 406,407,440,445 allah, P. A. 500, 533 371, 372, 373, 374, 376, 447 Paton, W. D. M. 240, 267, 288, - Panisset, J.-C. 163, 181 - see Friedmann, N. 369, 372, 334 Palay, S. L., see Grillo, M. A. 373,376,377,447 - Perry, W. L. M. 695, 696, 47, 52, 54, 56, 60, 71, 74, - see Jefferson, L. S. 368, 370, 699, 711, 723 778,807 450 - Rothschild, A. M. 589, 614 - see Williams, T. H. 786, 812 - see Mallette, L. E. 372, 453 - Thompson, J. W. 788, 811 Palkama, A. 585, 614 Parker, R. H. 0., see Burn, J. - Vizi, E. S. 793, 794, 795,796, - Hopsu, V. K. 24, 43 H. 122, 158,173 811 986 Author Index

Paton, W. D. M., Zar, M. A. Pepin, B., see Boudin, G. 867, Pettinger, W. A., Spector, S., 796,811 884 Horwitz, D., Sjoerdsma, A. - see Marley, E. 240, 266, 479, Peralta, L., see Costero, 1. 560, 619,657 531 607 Petzold, G. L., see Reik, L. 366, Patrick, R. W., see Axelrod, J. Perkins, J. P., see Walsh, D. A. 368,457 519 401,461 Pfaller, W., see Plattner, H. - see Hertting, G. 355, 359, Perkins, M., see Sidman, R. L. 563,614 814,838 130,170,183,815,842 Pfau, A., see Besser, M. 1. B. Paulsen, E. C., Hess, S. M. 149, - see Weiner,~. 130, 170,185 902,924 181,196,227 Perkins, M. E., see Moran, ~. Pfeifer, A. K., Galambos, E., Pauly, J. E., see Scheving, L. E. C.285,333,814,840 Gyorgy, L. 504, 533 119,182 Pernow, B., see Duner, H. 157, Pfeiffer, A. K., Szato, S., Pol• Pazery, L. M., see Scheckel, C. 174 kouits, M., Okros, 1. 61, 76 L. 496, 535, 863, 880, 895 - see Havel, R. J. 404, 449 Pfeiffer, R., see Philippu, A. Pearce, J., see Garland, H. 848, Perri, V., Sacchi, 0., Casella, C. 205,227 887 664,668,674,676,677,723 Phelan, E. L., see Laverty, R. Pearse, A. G. E. 47, 48, 49, 76 Perrino, 1., see Della Corte, L. 831,839 Peart, W. S. 2, 14 8,13 Philippu, A., Becke, H., Bur• Peaston, M. J. T., Bianchine, J. Perry, J. E., see Wiegand, R.E. ger, A. 500, 533 R. 87l, 874, 876, 893 504,537 - Heyd, G., Burger, A. 588, Peck, E., see Awapara, J. 188, Perry, M. C., Hales, C.~. 382, 614 219 383,455 - Pfeiffer, R., Schiimann, H. Pedersen, B., see Lieberman, Perry, T. L., Hestrin, M., J., Lickfeld, K. 205, 227 A.~.862,865,891 MacDougall, L., Hansen, S. - Schiimann, H. J. 251, 252, Pedersen, J. I., see Grav, H. J. 851,893 253,255,267,498,533,539, 415,448 - see Awapara, J. 188, 219 587,590,591,614,615,625, Peiss, C. ~., see McCook, R. D. Perry, W. L. M., Reinert, H. 626,627,637,638,641,642, 488,530 689,723 657 Pekkarinen, A., Scheinin, T. - see Goffart, M. 798, 807 - see Burger, A. 205, 220 M., ~anto, V. 912, 930 - see Guldberg, H. C. 859, 888 - see Haag, H. W. 241, 264, Pellegrino de Iraldi, A., Dug• - see Paton, W. D. M. 695, 914,927 gan, F., de Robertis, E. 61, 696,699,711,723 - see Schumann, H. J. 67, 76 Persson, H., Johnson, B. 298, 77,242,245,259,267 - Gueudet, R. 53, 56, 58, 60, 327,334 Phillipot, E., Goffart, M., Dres• 76 - see Anden, ~. E. 197, 198, se, A. 123, 132, 158, 181 - Jaim-Etcheverry, G. 60, 61, 206,219,737,756 Phillips, J. H., see Burch, G. E. 76 - see Ehinger, B. 763, 780, 24,40 - de Robertis, E. 50, 52, 53, 781,806 Phillis, J. W., see Chong, G. C. 56,58,76 Persson, T., Waldeck, B. 503, 533 98,105 - Zieher, 1. M. 120, 181 - see Hallstrom, T. 866, 888 - see Krnjevi6, K. 497, 529 -- de Robertis, E. 52, 56, Pertoft, H., see Lagercrantz, H. Philpot, F. J., see Burn, J. H. 76 248,249,250,266 27l, 280, 813, 816, 836 - see De Robertis, E. 47, 52, Pertsemlidis, D., Gitlow, S. E., Piccinelli, D. 96, 108 54, 56, 61, 73, 214, 222 Siegel, W. C., Kork, A. E. Pichler, H., Suko, J., Hertting, Pellerin, J., see Gelinas, R. 853, 901,913,930 G. 8, 14 887,902,904,906,907,908, Peskar, B., Hellman, G., Hert• Pick, J. 67l, 723, 731, 760 926 ting, G. 201, 204, 227 - de Lemos, C., Cranella, A. Pengelley, E. T., see Horwitz, Peters, B. H., see ~ibbelink, D. 52,76 B. A. 417, 450 W.901,930 Pieri, L., see Garattini, S. 500, Penhos, J. C., Wu, C. H., Dau• Peters, D. A. V., McGeer, P. L., 525 nas, J., Reitman, M., Le• McGeer, E. G. 848, 893 Piezzi, R. S. 18, 19, 43 vine, R. 374, 375, 455 Peters, J. J., see Hehman, K. Pincus, J. B., see ~atelson, S. Pennington, S. ~., see Brown, ~. 464, 527 112,181 H. D. 433, 443 Petersen, J. C., see Himwich, Pindell, M., see Belleau, B. 7, Pentreath, V. W., Cottrell, G. W. A. 465, 528 12 A.102,108 Peterson, D. D., see Seiden, L. Pinder, R. M. 873, 893 - see Cottrell, G. A. 80, 102, S. 503, 504, 535 Pinkston, J. 0., see Greer, C. 106 Peterson, E., see Barcroft, H. M. 2, 14 Penttila, O. 164,181 494,520 Piras, R., Staneloni, R. 402, Penttila, 0., Vartiainen, A. Peterson, R. F., see Skipski, V. 403,404,405,455 866,893 P. 592, 615 - see Staneloni, R. 403, 459 Peon, C., see Kabela, E. 318, Petillot, ~., see Schmitt, H. Pirch, J. H., ~orton, S. 505, 332 646,647,651,658 533 Pepeu, G., Giarman,~. J. 87l, Pettett, G., see Christian, D. R. Pirrll, A., see Boshart, C. R. 893 394,395,444 423,443 Author Index 987

Pisano, J. J., Creveling, C. R., Poeck, K., see Mantegazzini, P. Popov, N., Pohle, W., Rosier, Udenfriend, S. 189, 227 477,531 V., Matthies, H. lI8, 149, - see Crout, J. R. 912, 925 Pogrund, R. S., Drell, W., 181 Pivnicki, D., see Sourkes, T. C. Clark, W. G. 876, 879, 893 Porte, D. 422, 456 874,897 - see Clark, W. G. 191, 221 - Graber, A., Kuzuya, T., Plattner, H., Winkler, H., - see Hartman, W. J. 188,224 Williams, R. H. 419, 422, Hortnagl, H., Pfaller, W. Pogson, C. I. 388, 456 456 563,614 Pohl, S. L., Birnbaumer, L., - Williams, R. H. 422, 456 Pletscher, A. 281 Rodbell, M. 368, 456 Porter, C. C., Titus, D. C. 620, - Bartholini, G., Tissot, R. - see Birnbaumer, L. 382, 635,657 873,876,893 384,443 - Torchiana, M. L., Totaro, - Brossi, A., Gey, K. F. 814, - see Rodbell, M. 385, 457 J .. A., Stone, C. A. 625, 626, 841 Pohle, W., see Popov, N. lI8, 637,638,657 - Gey, K. F., Burkard, W. P. 149,181 - Totaro, J. A., Leiby, C. M. 504,506,533 Pohlmeier, H., see Matussek, 497,498,533,619,636,639, -- Zeller, P. 814, 841 N. 862, 892 657 - Shore, P. A., Brodie, B. 5, Pohorecky, L., Rust, J. H. 32, -- Stone, C. A. 823, 826, 15 43,600,614 841 - see Bartholini, G. 235, 262, Poirier, L. J. 847, 893 -- Burcin, A. 497, 533, 644, 496,497,520,851,853,863, - Singh, P., Boucher, R. 853, 657,823,841 868, 875, 876, 877, 879, 882 893 - Watson, L. S., Titus, D. C., - see Berneis, K. H. 250, 252, -- Sourkes, T. L., Boucher, Totaro, J. A., Byer, S. S. 262, 544, 558, 594, 606 R. 847, 868, 894 862, 894 - see Brodie, B. B. 498, 521 - Sourkes, T. L. 847, 856, 894 - see Lotti, V. J. 863, 891 - see Burkard, W. P. 814, -- Bouvier, G., Boucher, - see Stone, C. A. 468, 536, 836,862,884 R., Carabin, S. 154,181 618,639,646,647,652,659, - see Da Prada, M. 205,221, - see Bedard, P. 847, 851, 823,827,842 855,873,886 882 - see Torchiana, M. L. 623, - see Gey, K. F. 853, 867, 887 - see Lancaster, G. 847, 868, 624, 628, 635, 651, 659 - see Kuruma, I. 876, 891 891 Porter, J. C., see Kamberi, I. A. - see Schwartz, D. E. 499,535 - see Sharman, D. F. 847, 896 866,890 - see Tissot, R. 897 - see Sourkes, T. L. 847, 860, Porter, K. R., see Ashford, T. Plotnikova, S. I. 101, 108 897 P. 372, 442 - Kuzmina, L. V. 88,108 Poisner, A. M., Douglas, W. W. Portig, P. J., see Banister, R. J. Plotnikova, S. N., Govyrin, W. 587,614,914,930 19,39, 115, 171 A. 86, 108 - Trifar6, J. M., 248, 249, 256, Porto, A., see do Valle, J. R. Pluchino, R., see Pluchino, S. 257,259,267,539,595,596, 142,184 354,355,360 614 Portzehl, H., Caldwell, P. C., Pluchino, S. 356, 360, 733, 737, -- Douglas, W. W. 551, Ruegg, J. C. 586, 614 760,834,841 553, 558, 559, 560, 614 Poschel, B. P. H., Ninteman, - Muskus, A. J., Pluchino, R. - see Douglas, W. W. 424, F. W.502,533 354,355,360 446,549,550,560,562,584, Poskanzer, D. C., see Schwab, - Trendelenburg, U. 340, 360, 586,589,592,608 R. S. 869, 895 726, 734, 760, 834, 841 - see Malamed, S. 559, 596, Posner, H. S., see Mitoma, C. - Van Orden, L. S., III., 597,613 878,892 Drask6czy, P. R., Langer, - see Trifar6, J. 555, 558, 560, - see Weil-Malherbe, H. 244, S. Z., Trendelenburg, U. 596,616 258, 259, 269, 495, 505, 537 734, 760 Polesky, H. ]'., see Staley, N. Posner, J. B., Hammermeister, - see Brimijoin, S. 730, 735, A. 919, 920, 932 K. E., Bratvold, G. E., 736, 756 Polgar, J. G., see Hughes, R. C. Krebs, E. G. 404, 456 - see Trendelenburg, U. 307, 865,866,869,889 - Stern, R., Krebs, E. G. 401, 327,334,339,340,342,348, Poliakoff, S., see Karoum, F. 402,456 350,361,729,730,735,737, 876,877,890 Posternak, Th., see Ho, R. J. 738, 744, 746, 751, 752, 754, Polikarpova, L. I. 169, 181 382,383,450 761,817,833,843 Polkouits, M., see Pfeiffer, A. Potter, L. T. 50, 52, 58,76,317, Plummer, A. J., see Maxwell, R. K. 61, 76 323,334,565,570,571,572, A. 337, 354, 360, 727, 760 Poll, H., Sommer, A. 89,108 590,603,614 - see Schneider, J. A. 517, 535 Pollitt, R. J., see Boulton, A. - Axelrod, J. 189, 196, 217, Podgornaya, G. 122, 181 A. 850, 851, 884 227,239,267,468,533,574, Poch, G. R., Kopin, I. J. 338, Pomerantz, S., see Goldstein, 614, 629, 630, 657 361,636,657 M. 874, 888 -- Kopin, 1. J. 468, 533, - see Kukovetz, W. R. 394, Pontasse, E. F., Gifford, R. W. 629,658 395,396,452 914,915,930 - Cooper, T., Willman, V. L., - see Musacchio, J. M. 503, Pooler, K., see Lebovitz, H. E. Wolfe, D. E. 614, 813, 815, 532 422,452 816, 822, 830, 841 988 Author Index

Potter, L. T., see Axelrod, J. Prusinger, S. B., Williamson, Quastel, J. H. 6, 15 338, 357, 827, 836 J. R., Chance, B., Paddle, - see Pugh, C. E. M. 271, 281 - see Hertting, G. 202, 224, B. M. 413, 415, 456 Quilliam, J. P., Shand, D. G. 630,654 - see Lindberg, O. 409, 412, 712,723 - see Wolfe, D. E. 52, 56, 78, 413,453 - Tamarin, D. L. 814, 841 200, 216, 230, 815, 844 - see Williamson, J. R. 409, - see Jones, K. B. 662, 720 - see Wurtman, R. J. 127, 412,413,414,415,462 Quinton, R. M., see Halliwell, 185 Prusoff, W. H., Blaschko, H., G. 500, 527 Poulter, G. A., see Drain, D. J. Ord, M. G., Stocken, L. A. 497,524 249,267 Raab, A. W., see Saari, W. S. Povalski, H., see Maxwell, R. Pruss, T. P., Maengwyn-Davies 623,625,658 A. 337, 354,360, 727, 760 G. D., Wurzel, M. 658 Raab, W., Gigee, W. 170,181, Powell, C. A., see Drummond, - see Wurzel, M. 314, 335 197, 206, 228, 816, 841 G. I. 401,402,427, 446 Pryor, J., Berthet, J. 373, 375, - Humphreys, R. J. 816, 841 Powell, C. E., Slater, I. H. 285, 456 Rabadjija, M., see Weiner, N. 334,814,841 Pryse-Davies, J., Dawson, J. 194,230 Poyart, C. F., Nahas, G. G. M. P., Westbury, G. 922, Rabhun, J., Feinberg, S. M., 389,456 923,930 Zeller, E. A. 271, 281 - Vulliemoz, Y., Nahas, G. G. - see Anthony, P. P. 917, 919, Rabin, C. B. 930 389,456 924 Rabinovitch, A., see Sourkes, Prange, jr., A. L., see McCurdy, - see Collins, G. G. S. 881, 885 T.L. 189, 191,228,878,897 R. L. 646, 656 Przegalinski, E., see Maj, J. Rabinowitz, D., see Edgar, P. Prasad, K. N., see Van Woert, 504,530 421,446 M. H. 857, 898 Pscheidt, G. R., Haber, B. 147, Rabinowitz, M., Desalles, L., Pratesi, P., Blaschko, H. 352, 181 Meisler, J., Lorand, L. 401, 361 - Himwich, H. E. 118, 154, 456 Prelog, V., see Cahn, R. S. 623, 181,505,533 Rachmanova, T. B., see Mat- 652 - Morpurgo, C., Himwich, H. Iina, E. Sch. 123, 179 Premalatha, K., see Haranath, E. 504, 505, 534 Racker, E. 384, 456 P. S. R. K. 911, 927 - see Costa, E. 496, 523 - Proctor, H. 6, 15 Plescott, L. F., Buhs, R. P., Pugh, C. E. M., Quastel, J. H. Radley, J. M. 425, 456 Beattie, J. 0., Speth, O. C., 271,281 Rafael, J., Klaas, D., Hohorst, Trenner, N. R., Lasagna, L. Pugsley, T. A., see Johnson, G. H.-J. 412, 456 620,658 E. 628, 638, 640, 655 - Ludolph, H.-J., Hohorst, H. Preziosi, P., see De Schaepdry• Pullar, I. A., Weddell, J. M., J.412, 415, 456 ver, A. F.182 Hanieh, A., Ahmed, R., - see HohOl'st, H.-J. 412, 450 Preziosi, T. J., see Morgan, J. Gillingham, F. J. 859, 872, Ragland, R., see Bhagat, B. P. 862,892 873,894 647,652 Price, H. L., see Valk, A. De T., Pumphrey, R. J., see Bronk, Rahamimoff, R., see Dodge, F. jr. 112,184 D. W. 685, 716 A. 590, 608 Price, K., see Pare, C. M. B. Puppi, A., see Benedeczky, I. Rahn, K. H. 169, 182 856,893 596,606 - Gilfrich, H. J., OIbermann, Pridham, J. B., see Andrews, Purkhold, A., see Euler, U. S. M.646,648,658 R. S. 852, 881 von 126, 128, 129, 161, 166, - see Lindmar, R. 627, 634, Priestley, J. T., Kvale, W. F., 167,175,198,222,576,609, 656 Gifford,R. W.901,911,930 813, 815, 837 - see MuschoII, E. 23, 43, 169, - see Gifford, R. W. 900, 926 Purves, M. J., see Biscoe, T. J. 180, 624, 627, 628, 642, 657 Priimak, E. K. 130, 181 23,24,39,40 Raisman, G., see Matthews, M. Prince, L. N., see Vogel, W. H. Purves, R. D., see Blackman, R. 22, 39, 43 853,854,898 J. G. 664, 668, 672, 674, Raisanen, L., see Eranko, O. Prockop, D., see Spector, S. 675,677, 715 32, 41, 121, 122, 175 272,282,505,536 Pushpathadam, J. J., Barbeau, Raisman, G. 61, 76 Proctor, H., see Racker, E. 6, A, 858, 894 - see Matthews, M. R. 70, 76, 15 Pustovoitova, Z. E., see Manuk• 784,786,787,810 Prokesch, J. C., see Cabana, B. hin, B. N. 117, 143,180 Rail, T. W., Kakiuchi, S. 427, E. 906, 925 Pyle, R. 913, 930 456 Prout, G. I., see Marley, E. 34, Pyper, A. S., see Coupland, R. - Sutherland, E. W., Wosi• 43,479,531 E. 17,26,41,48,50, 73 lait, W. D. 370, 456 Prout, T. E., see Schimke, R. Pyron, J. T., see Nakano, J. - see Craig, J.W. 401, 404, 445 N. 901, 931 385,455 - see Kakiuchi, S. 427, 428. Prusinger, S. B. 413, 414, 456 451 - Cannon, B., Ching, T. M., Quan, L., see Boulton, A. A. - see Klainer, L. M. 401, 427, Lindberg, O. 413, 456 851,884 451 -- Lindberg, O. 409, 412, Quastel, D. M. J., see Elm• - see Murad, F. 367, 371, 390, 413,456 qvist, D. 790, 806 392,396,399,404,405,455 Author Index 989

RaIl, T. W., see Sattin, A. 427, Rasmussen, H., see Kimmich, Reinhold, H., see Mahaux, J. 458 G. A. 372, 377, 451 E. 912, 929 - see Sutherland, E. W. 10, - see Nagata, N. 433, 455 Reinius, S., see Fuxe, K. 46, 61, 15,367,369,401,460 Rastgeldi, S. 122, 182 67,74 Ramon, F., see Costero, 1. 560, Rastogi, K. S., see Campbell, J. Reis, D. J., Weinbren, M., Cor• 607 422,444 velli, A. 118, 119, 120, 151, Rand, M. J., Ridehalgh, A. 765, Rathey, V., see Van Woert, M. 182 811 H. 862, 865, 866, 898 Reit, E., see Aiken, J. W. 662, - Varma, B. 768, 811 Ratzenhofer, M., Aubock, L., 715 - Whaler, B. C. 766, 811 Miiller, O. 909, 911, 915,930 - see Cervoni, P. 726, 756 - Wilson, J. 776, 811 - Miiller, O. 31, 43, 600, 615 - see Lewis, G. P. 709, 710, - see Brandon, K. W. 584, Ray, C., see Blackman, J. G. 721 606, 762, 764, 765, 774, 804 664,666,669,670,671,672, Reitman, M., see Penhos, J. C. - see Burn, J. H. 5, 9, 12,197, 673, 674, 675, 677, 695, 715 374,375,455 210,220,277,280,336,337, Ray, T. K. 368, 456 Reitter, H. 470, 471, 483, 534 340,357,512,521,584,607, - see Marinetti, G. V. 368, Reivich, M., Glowinski, J. 466, 762,763,764,766,782,804, 377,382,453 534 805 Raymond-Tremblay, D., see Remine, W. H., see Levit, S. A. - see Chang, V. 765, 805 Barbeau, A. 858, 882 929 - see Day, M. D. 205, 221, Raymondeaud, C., see Sig• Remolina, J., see Acheson, G. 498,524,618,631,647,651, wald, J. 864, 896 H.689,715 653 Read, J. B., Burnstock, G. 116, Renfrew, J. W., see Hutchin• - see Farmer, J. B. 791, 806 128,182 son, R. R. 488, 528 - see Holton, P. 763, 808 Recant, L., see Devrim, S. 420, Rennick, B. R. 855, 894 - see Macmillan, W. H. 169, 446 Renold, A. E. 419, 421, 457, 179 Rech, R. H. 467, 534 599,600,615 Randall, W. C., see McCook, R. - Domino, E. F. 476, 534 - Cahill, G. F., jr., Leboeuf, D. 488, 530 - see Moore, K. E. 502, 506, B., Herrera, M. G. 390, 457 Randle, P. J., Garland, P. B., 532 - see Ho, R. J. 382, 383, 450 Hales, C. N., Newsholme, Rechardt, L., see Eranko, O. - see Lambert, A. E. 420, 421, E. A. 402, 456 781,806 452 - see Coore, H. G. 421, 445 Reddy, V., Moran, N. C. 318, - see Letarte, J. 382, 383, 453 - see Denton, R. M. 388, 445 334 Renson, J., Weissbach, H., - see Garland, P. B. 402, 448 Reddy, W. J., see Laraia, P. J. Udenfriend, S. 864, 894 Randrup, A., Munkvad, 1. 502, 395,452 - see Bacq, A. M. 273, 280, 534 Redfield, B. G., see Hess, S. M. 506,519, 754, 756, 814, 836 - Rasmussen, E. B., Munk- 224 Renyi, A. L., see Ross, S. B. vad, T. 236, 267 Reed, N., Fain, J. N. 409, 411, 212,228,337,350,351,361, - Scheel-Kriiger, J. 504, 534 414,457 500,534,737,760 Rang, H. P. 317, 334 - see Fain, J. N. 409, 412, Repin, 1. S., see Kalinina, N. - Ritchie, J. M. 673, 686, 691, 414,447 Regen, D. M., Terrell, E. B. A. 483, 529 692,723 Resch, H., see Lembeck, F. Ranson, S. W., Billingsley, P. 374,457 750,759 R. 690, 723 Rehn, O. N. 126, 129, 161, 167, - see Billingsley, P. R. 688, 182, 190, 228, 814, 841 Resnick, R. H., Gray, S. J., 715 Reichel, G., see Dengler, H. Koch, J. P., Timberlake, Rao, N. R., see Haranath, P. S. 191,221 W. H. 880, 894 R. K. 911, 927 Reid, J. L., see Chalmers, J. P. Retzius, G. 89, 108 Rao, N. S. 860, 861, 873, 894 877 Reutter, F. W., see Friend, G. Rapela, C. E., Gordon, M. F. Reid, J. V. 0., see Gordon, R. 271,280 115,182 194,223 Reutter, K. 88, 89, 108 - see Houssay, B. A. 140, 178 Reiffenstein, J., see Belleau, B. Revol, L., see Matthieu, P. 857, Raper, C., Bowman, W. C. 800, 7,12 892 811 Reiffenstein, R. J. 727, 760 Revuelta, A., see Bloom, F. E. - Wale, J. 316, 334 Reik, L., Petzold, G. L., Hig• 47,64,67,72,828,836 - see Bowman, W. C. 401, gins, J. A., Greengard, P., - see Groppetti, A. 857, 888 402,443,796,797,798,799, Barrnett, R. J. 366, 368, Revzin, A. M., see Costa, E. 800,804 457 787,791,805 Raphy, B., see Boudin, G. 867, Reimann, E. M., see Brostrom, Reynolds, R. W. 489, 534 884 M. A. 404, 443 Ribaupierre, F. de, see Siegrist, Rasmussen, E. B., see Randrup Reinert, H. 695, 708, 709, 723, G. 22, 39, 44, 52, 70, 77,786, A. A. 236, 267 784,787,791,811 787,811 Rasmussen, H., Tenenhouse, A. - see Davey, M. J. 272, 280 Rice, L., see Mayer, S. E. 395, 372,396,421,423,424,456, - see Gertner, S. B. 689, 718 454 589,614 - see Perry, W. L. M. 689, 723 Richards 827 990 Author Index

Richards, J. G., Tranzer, J. P. Ritchie, J. M., see Goffart, M. Robinovitch, M. R., Smuckler, 67, 76 797,807 E. A., Sreebny, L. M. 426, - see Tranzer, J. P. 46, 48, - see Rang, H. P. 673, 686, 457 56,64,67,78,823,824,828, 691,692,723 Robins, E., Robins, J. M., 843 Ritzen, 1\1., see Bjorklund, A. Croninger, A. B., Moses, S. Richardson, J. A., Wood, E. F. 787,803 G., Spencer, S. J., Hud· 768,811 - see Bloom, G. 18, 40, ll3, gens, R. W. 854, 894 Richardson, K. C. 47, 52, 53, 56, 134,172 Robins, J. M., see Robins, E. 58,71,76,214,228,815,841 - see Caspersson, T. 17, 40 854,894 - see Michaelson, 1. A. 58, 76 - see Fuxe, K. 467, 525 Robinson, Burnstock, 54 - see Roth, C. D. 52, 77 - see Hamberger, B. 23, 42, Robinson, B. W., Mishkin, M. - see Sjoqvist, F. 56 77,821, 922,927 489,534 842 - see Johnson, G. E. 621, 655 Robinson, D., see LeBlanc, J. - see Wolfe, D. E. 52, 56,78, - see Norberg, K.·A. 786, 787, 132,179 200,216,230,815,844 811 - see Murphy, G. F. 873, 893 Richter, D. 132, 182, 270, 271, - see Ostlund, E. 134, 181 Robinson, D. S., see Jequier, 281 Rivera·Calimlim, L., Dujovne, E. 879, 890 - see Blaschko, H. 5, 12, 271, C. A., Morgan, J. P., La· - see Salaman, M. R. 390, 458 280,620,652 sagne, L., Bianchine, J. R. - see Wing, D. R. 390, 462 - see Green, D. E. 8, 13 871,894 Robinson, 1. M., see Bhagat, B. Riddell, D. H., Schull, L. G., - Morgan, J. P., Dujovne, C. 737,756,772,803 Frist, T. F., Baker, T. D. A., Bianchine, J. R., La· Robinson, J., see Burn, J. H. 901,930 sagna, L. 871, 894 271,280,816,836 Ridell, D. H., see Scott, H. W. Rivest, P., see Leduc, J. 417, Robinson, J. A., see Kosterlitz, 901,931 452 H. W. 792, 809 Ridehalgh, A., see Rand, M. J. Rizack, M. A. 388, 389, 457 Robinson, R. 905, 9ll, 920, 765,811 Roaf, H. E. 17,43 921,930 Riechert, T., see Hassler, R. - Nierenstein, M. 17, 43 - Monro, A. F. 34, 44 847,889 Ro'ane, J. T., see Blecher, M. - Smith, P. 912, 930 - see Metzel, E. 854, 856, 858, 382,390,443 -- Whittaker, S. R. F. 913, 892 Robb·Smith, A. H. T., see 930 Rieker, M. S., see Furchgott, Blaschko, H. 593, 601, 606, - see Kelleher, J. 912, 928' R. F. 212, 223, 303, 332, 906,907,908,909,911,924 - see Stott, A. W. 620, 659 634,654,730,731,757 Robbins, D. J., see Masri, 857, Robinson, R. L. 241, 267, 914, Rifkin, M., see Scudder, C. L. 892 930 ll8,182 deRobertis, E., see Sabatini, Robison, G. A., Butcher, R. W., Rijntjes, N. V. M., see Van M. T. 821, 841 Sutherland, E. W. 10, 15, Rossum, J. M. 872, 898 Roberts, B. J., see Matthews, 319,334,363,367,368,392, Riker, W. K. 695, 698, 699, R. J. 710, 722 393,396,405,406,407,441, 700, 7ll, 712, 723 Roberts, D. J., see Abbs, E. T. 457 - see Hunt, C. C. 664, 667, 506,518 -- 0ye, I., Morgan, H. E., 668, 670, 671, 689, 720 - see Broadley, K. J. 501, 521 Sutherland, E. W. 392, 393, Riley, V., Fortner, J. G. 49, 76 - see Chambers, D. M. 470, 395,396,457 Riley, W. D., Delange, R. J., 505,507,522 -- Sutherland, E. W. 462 Bratvold, G. E., Krebs, E. - see Jones, B. J. 470, 528 - see Dobbs, J. W. 406, 407, G.404,457 - see Street, D. M. 128, 132, 446 - see Delange, R. J. 401, 403, 184 - see Sutherland, E. W. 367, 445 Roberts, J. C., Smith, R. E. 371,395,396,460 Rimoin, D. L., see Schimke, R. 4ll,457 Rocha e Silva, M., Sproull, D. N. 901, 931 - see Smith, R. E. 4ll, 459 H. 493, 534 Ringler, 1., see Boshart, C. R. Roberts, L. S. 102 RodaW, K., see Issekutz, B., jr. 423,443 Roberts, W. C., see Glenner, G. 404,450 Rinne, U. K. 67, 76 G. 923, 926 Rodbell, M. 379, 381, 382, 383, - Sonninen, V. 153, 182, 861, Robertshaw, D., see Findlay, 389,457 872,875,894 J. D.471,484,491,525 - Birnbaumer, L., PoW, S. L. - see Hyyppa, M. 866, 890 Robertson, D., see Michelakis, 385,457 Risley, P. L., see Eliasson, R. A. M. 864, 892 - Jones, A. B. 382, 457 163,175 Robertson, D. M., Hendry, W. -- Chiappe de Cingolani, G. Ritchie, J. M., Straub, R. W. S., Vogel, F. S. 920, 930 E., Birnbaumer, L. 382, 686,691,723 Robertson, M. 1., see Abbs, E. 384,457 - see Armett, C. J. 703, 706, T. 777, 803 - see Birnbaumer, L. 381, 715,765,803 Robertson, P. A. 708, 723 382, 384, 386, 443 - see Den Hertog, A. 691, 717 Robertson, W., see Bitensky, - see Clausen, T. 382, 383, - see Douglas, W. W. 690, M. W.368,443 390,445 709,717,774,806 - see Greer, W. E. R. 901, 927 - see Pohl, S. L. 368, 456 Author Index 991

Rodnight, R, see Weller, M. Rosen, S. M., see Rosen, O. M. Ross, S. B., Haljasmaa, O. 506, 428,461 433,457 534 Rodrigues-Pereira, E., see Gar• Rosenblueth, A., see Cannon, - Renyi, A. L., 337 350, 351, rett, J. 914, 926 W. B. 2, 13, 813, 821, 832, 361,500,534,737,760 Rodriguez, H. A., see Albores• 836 -- Brunfelter, B. 212, 228, Saavedra,J.909,924 Rosengren, A. M., see BertIer, 351,361 Rodriguez, R R, see Gagliar• A. 241, 262, 465, 495, 496, Rossi, P., Kaufman, L., Ruzi• dino, J. J. 421, 447 498,520 cka, F. F., Panke, W. 913, Rodriguez de Lores Arnaiz, G., - see Cegrell, L. 131, 133, 168, 930 de Robertis, E. 504, 534 173 Rossum, J. M., van 325, 327, - see Alberici, M. 504, 518 - see Ehinger, B. 780, 781, 329,335,498,534,623,658, - see DeRobertis, E. 61, 73, 806 854,898 427,446 Rosengren, E., Sjoberg, N.-O. - Ariens, E. J. 288, 335 Roemer, C., see Jacobi, C. 482, 127, 164, 182 - Hurkmans, J. A. T. M. 623, 528 - see Anden, N. E. 813, 816, 624,658 Roer, E. M., see Rubin, R P. 828,835 - Wijffels, C. C. B., Rijntjes, 124,182 - see Bertler, A. 4, 12, 112, N. V. M. 872, 898 118, 123, 125, 128, 131, 133, - see Cools, A. R 854, 865, Roffi, J. 21, 32, 44, 122, 182, 147, 148, 149, 150, 152, 153, 232,267 885 160, 161, 165, 166, 167, 170, - see Hubert, J. W. A. 846, - Margolis, F. 32, 44 172,188,220,236,237,241, 889 - see Margolis, F. L. 903, 929 242, 262, 872, 883 - see Lammers, A. J. 496, Rogers, A. F., see Field, E. J. - see Bjorklund, A. 153, 172, 530, 863, 865, 891 516,525 787,803 Roth, B. H., Stjarne, L., Le• Rogers, D. C., see Bennet, M. - see Carlsson, A. 5, 13, 244, vine, R. L., Giarman, N. J. R 731, 756 263,336,358,517,522,814, 902,916,930 Rogers, K. J., see Angel, A. 836 Roth, C. D., Richardson, K. C. 506,519 - see Dahl, E. 82, 83, 91, 92, 52, 77 Rognstad, R, Katz, J. 389, 93, 94, 95, 96, 106 Roth, G. M., Flock, E. V., 390,457 - see Falck, B. 125, 126, 128, Kvale, W. F., Waugh, J. - see Katz, J. 389, 451 161,176,901,905,926 M., Ogg, J. 901,930 Rood, M. de, see Mahaux, J. E. - see Jonasson, J. 245, 265 - see Gifford, R W. 900, 926 912,929 - see Magnusson, J. 119, 154, Roth, L. J., Schoolar, J. C., Roos, B.-E. 855, 894 179 Barlow, C. F. 534 - Sjostrom, R. 846, 894 - see Owman, C. 127, 164,181 Roth, M., see Schwartz, D. E. - Werdinius, B. 506, 534 Rosenmund, K. VV., Dornsaft, 499,535 - see Anden, N.-E. 498, 518, H. 852, 894 Roth, R. H., Stjarne, L., 519,855,859,865,866,872, Rosenstein, B. J., Engelman, Bloom, F. E., Giarman, N. 874,875,881 K. 918, 930 J. 50,53, 71, 77 - see Gottfries, C. G. 856, 860, Rosenthal, 1., see Greenberg, -- v. Euler, U. S. 194, 196, 888 R E. 909, 911, 919, 920, 927 228 Rosenthal, 1. M., Greenberg, -- Levine, R. J., Giarman, - see Johansson, B. 859, 890 R., Goldstein, R., Kathan, N. J. 235, 267 - see Lycke, E. 847, 870, 891 R, Cadkin, L. 903, 905, - Stone, E. A. 193, 228, 498, - see Olsson, R 846, 860, 893 909,930 534 Rorie, M., see Kirshner, N. 236, -- Kathan, R, Falk, G. - see Boadle, M. C. 195, 220 265 W., Wong, R. 918, 919, 920, - see Stjarne L. 53, 68, 77, Rosazza, J., see Sih, C. J. 852, 930 189,194,195,198,201,213, 896 Rosenthal, J., see Genest, J. 229,236,240,268,498,536, Rose, C., see Wurtman, R. J. 130,169,176 616 874,899 RosIer, V., see Popov, N. 118, Rothballer, A. B. 472, 476, 477, Rose, C. M., Chou, C., Wurt- 149,181 534 man, R J. 872, 894 Ross, B., see Donath, A. 901, Rothlin, E., Cerletti, A. 314, Rosell, S. 387, 457 905,912,913,925 334 - Axelrod, J. 208, 228 Ross, B. D., Hems, R., Freed• Rothman, S., see Coon, J. M. - Sedvall, G. 210, 228 land, R. A., Krebs, H. A. 584,607,764,805 -- Ullberg, S. 871, 894 374,458 Rothschild, A. M., see Paton, - see Ballard, K. 387, 442 Ross, C. A., see Stone, C. A. W. D. M. 589, 614 - see Fredholm, B. 387, 447 468,536,646,647,659,823, Roudot, P., see Boudin, G. 867, - see Oro, L. 387, 455 842 884 Rosell-Perez, M., Larner, J. Ross, D. M. 87, 108 Rouillier, C., see Siegrist, G. 22, 401,457 Ross, G. T., see Wurtman, R. 39, 44, 52, 70, 77, 786, 787, Rosen, J. A. 868, 894 J. 232, 235,269, 903, 933 811 Rosen, O. M., Rosen, S. M. 433, Ross, 1., see Leon, A. S. 873, Rowe, J., see Klein, D. C. 430, 457 891 451 992 Author Index

Rowell, L. B., see Masoro, E. J. Ruthven, C. R. J., see Jones, Saffran, M., see Matthews, E. 404,454 N.F. 851, 890, 913, 916, 928 K. 585, 613 Roy, S., Wolman, L. 857, 894 - see Karoum, F. 876, 877, Sage, H. J., Smith, W. J., Rubenson, A., see Henning, M. 890 Kirshner, N. 34, 44, 540, 864,889 - see Morgan, C. D. 875, 892 555,615 Rubin, R. P. 595, 615 - see Sandler, M. 845, 848, - see Kirshner, N. 68, 75,540, - Cohen, M. S., Harman, S. 851, 853, 855, 858, 870, 874, 555,557,560,562,565,587, M., Roer, E. M. 124, 182 875,878,895 612 - Feinstein, M. B., Jaanus, S. Rutledge, C. 0., Jonason, J. Saint Cyr, S., see Sourkes, T. L. D., Paimre, M. 586, 615 495,534 874, 897, 920, 921, 932 - Jaanus, S. D. 549, 587, 615, - Weiner, N. 193, 228, 498, Sakamoto, A., see Cotzias, G. 914,930 534 C.857,885 - Miele, E. 584, 589, 615 - see Weiner, N. 232, 233, Sakharov, D. A., Zz.-Nagy, 1. - see Douglas, W. W. 549, 236,269 95,108 550,583,586,587,589,591, Ruzicka, F. F., see Rossi, P. Sakurai, T., see Nukada, T. 608,693,717 913,930 504,533 - see Jaanus, S. D. 589, 611 Ryan, L., see Jost, J.-P. 375, Salaman, M. R., Robinson, D. - see Miele, E. 589, 613 450 S.390,458 Ruckebusch, Y., Grivel, M. L., Ryan, R. L., see Hofmann, W. - see Wing, D. R. 390, 462 Laplace, J. P. 482, 484, W.860,889 Salganicoff, L., see Cheung, W. 534 Rychlik, 1., see Dousa, T. 405, Y. 427, 444 - Laplace, J. P., Grivel, M. L. 446 - see DeRobertis, E. 37, 41 484,491 534 Ryd, G. 190, 228 Salmoiraghi, G. C. 319, 334 Rude S. 81, 89, 90, 91, 108 - Sjostrand, N. O. 126,182 - see McCubbin, J. W.· 709, - Coggeshall, R. E., van Or- - see Euler, D. S. von 129, 722 den,L. S.89,96,108 166,175 Salmon, G. K., Ireson, J. D. Rudman, D. 458 Rylander, E., see Lindberg, O. 651,658 - Del Rio, A. E. 387, 458 412,453 Salomon, Y., Schramm, M. 424, Rudzik, A., see Cha, K.-S. 127, 458 164,173 Saari, W. S., Raab, A. W., Salpeter, E. E., see Salpeter, M. Rudzik, A. D., Miller, J. W. Engelhardt, E. L. 623, 625, M.77 127,182 658 Salpeter, M. M., Bachmann, L., Riiegg, J. C., see Portzehl, H. Sabatini, D. D., Bensch, K. G., Salpeter, E. E. 77 586,614 Barrnett, R. J. 48, 77 - see Budd, G. C. 52, 56, 58, Ruffin, J. M., see Anlyan, W. - see DeRobertis, E. D. 248, 60,73 G. 861, 881 263,562,563,596,599,608 Salt, P. J., see Iversen, L. L. Rummel, W., see Bleckman, 1. Sabatini, M. T., DeIraldi, A. 749, 758 796,803 P., deRobertis, E. 821, 841 Salva, J. A., see Valdecasas, F. - see J urna, 1. 796, 808 Sabbot,1. M., see Mandell, A. J. G. 354, 362 Rush, R. A., see Geffen, L. B. 501,531 Salvador, R. A., Colville, K. I., 74, 217, 223, 574, 575, 602, Sabuncu, N. 846, 894 April, S. A., Burns, J. J. 604,609 Sacarrao, G. F. 18,44 286,334 Ruskell, G. L. 52, 77 Sacchi, 0., see Perri, V. 664, - April, S. A., Lemberger, L. Russel, R., see Johnson, G. A. 668,674,676,677,723 423,458 502,528 Saccomanno, G., see Kuntz, A. - see Burns, J. J. 286, 331 Russell, V., see Bitensky, M. 688, 721 Salvi, M. L., Angeletti, P. D., W. 368, 369, 443 Sachs, C., see Hamberger, B. Frati, L. 819, 841 Russell, W. R., see Kremer, M. 199, 209, 224, 622, 654 Salzmann, R., Pacha, W., 847,891 - seeJonsson,G. 203,225,611 Taeschler, M., Weidmann, Rust, J. H., see Pohor-ecky, L. - see Malmfors, T. 814, 815, H.313,334,353,361 32,43,600,614 817, 826, 827, 831, 840 Samorajski, T., Marks, B. H., Rust, L. A., see Nagatsu, T. Sack, H., Koll, J. F. 900, 930 Webster, E. J. 198, 199, 126,161,167,180,813,816, Sacks, O. W., Kohl, M. 861, 211,228 822,840 865,894 Samovajski, T., see Ordy, J. M. Ruther, E., see Halaris, A. 61, -- Schwartz, W. F., 160, 181 74 Messeloff, C. R. 861, 894 Sampietro, R., see Sol cia, E. Ruthven, C. R. J., Karoum, F., - Messeloff, C. R., Schwartz, 48, 77 Anah, C. 0., Chapman, J., W. F. 861, 894 Sampson, S. R., Biscoe, T. J. Sandler, M. 874, 894 --- Goldfarb, A., Kohl, 24,44 - Sandler, M. 913, 920, 921, M.865,895 - see Biscoe, T. J. 23, 24, 39, 930 Sadavongvivad, C., see Aviado, 40 - see CaIne, D. B. 855, 859, D. M. 161,171 - see Douglas, W. W. 585, 874, 875, 876, 877, 884 Saelens, J. K., Schoen, M. S., 586,589,608 - see Goodwin, B. L. 858, 866, Kovacsics, G. B. 112, 134, Samson, F. E., see Schmitt, F. 888 149,182 0,602,615 Author Index 993

Samuel, E. P. 784, 811 Sano, I., Gamo, T., Kakimoto, Schaepdryver, A. F. de, see Samuels, H. H., see Tomkins, Y., Taniguchi, K., Take• Amery, A. 627,652,916,924 G. M. 375, 460 sada, M., Nishinumani, K. - see Chubb, I. W. 576, 579, Sanan, S., Vogt, M. 148,182 118,155,182 580,603,604,607 Sanbe, S. 688, 723 Santibaiiez, H. G., see Mante• - see De Potter, W. P. 214, Sanchez Garcia, P., see Furch• gazzini, P. 477, 531 217,221,574,576,578,588, gott, R F. 634, 654, 742, Saperstein, R, see Fain, J. N. 590,604,608 757 409,447 - see Hoszowska-Owczarek, Sandler, M. 849, 851, 853, 856, Sapira, J. P., Altman, M., A. 353, 359 861,867,874,895,900,911, Vandyk, K., Shapiro, A. P. - see Laduron, P. 214, 225 920 901,931 - see Langer, S. Z. 754, 759 - Collins, G. G. S., Youdim, Sarcione, E. J., see Sokal, J. E. - see Mahaux, J. E. 912, 929 M. B. H. 858, 895 367,371,459 - see Nagasaka, M. 298, 333 - Goodwin, B. L., Ruthven, Sardi, G., see Feruglio, F. S. - see Smith, A. D. 557, 575, C. R. J., Caine, D. B. 878, 915,926 576,578,579,580,581,588, 895 Sargent, T., see Shulgin, A. T. 616 - Karoum, F., Ruthven, C. 866,896 Schaeppi, U. 477, 534 R J. 848, 895 Sarosi, G., Doe, R. P. 901, 931 Scharer, K., see Theiss, E. 863, --- Caine, D. B. 874, 895 Sarova-Pinhas, I., see Braham, 897 --- Southgate, J., Caine, J. 850, 851, 863, 884 Schain, R J. 470, 506, 534 D. B. 851, 878, 895 Sasaki, T., Litwack, G., Baser• SchalIy, A. V., see Couch, E. F. - Ruthven, C. R J. 845, 848, ga, R. 425, 426, 458 563,607 853, 858, 870, 875, 895 Sasko, H., see Goldberg, N. D. Schanberg, S. M., Schildkraut, -- Caesar, P. M. 855, 895 404,448 J. J., Kopin, I. J. 467, 468, - Youdim, M. B. H., South- - see Lamer, J. 404, 452 499,534 gate, J., Hanington, E. 850, Sato, T., Ishida, N., ltoh, C., - see Schildkraut, J. J. 500, 895 Wada, Y., Yoshinaga, K. 535 - Bonham, Carter S. 850, 851, 905,912,931 Schaumann, O. 623, 648, 658 883 - see ltoh, C. 123, 178, 232, Schayer, R. W. 270, 281 - see Caine, D. B. 850, 855, 265,906,912,928 - Smiley, R. L., Davis, K. J., 859,866,867,874,876,877, Sato, T. L., Sjoerdsma, A. 913, Kobayashi, Y. 270, 272, 281 884 931 -- Kaplan, E. H. 270, 281 - see Challacombe, D. N. 850, Satoh, M., see Takagi, H. 498, -- Kennedy, J. 270, 272, 885 536 281 - see Collins, G. G. S. 858, Sattin, A., Rail, T. W. 427, 458 Schear, M. J., see Yahr, M. D. 869,881,885 Savana, S., see Couch, E. F. 861,867,899 - see Contractor, S. F. 871, 563,607 Scheckel, C. L., Boff, E. 498, 885 Savio, V., see Paii6, M. 686, 723 535 - see Davison, A. N. 853, 867, Sawyer, M. E., Mac, K., -- Pazery, L. M. 496, 535, 886 Schlossberg, T. 813, 841 863,880,895 - see Goodwin, B. L. 858, 866, Sayre, D. F., see Anton, A. H. Scheel-KrUger, J., see Rand• 888 112, 116, 118, 119, 131, 140, rup, A. 504, 534 - see Jones, N. F. 851, 890, 142, 144, 147, 149, 154, 159, Scheiffarth, F., see Tiedge, F. 913,916,928 160,161,163,164,166, 167, 923,933 - see Karoum, F. 876, 877, 171,852,881,905,911,913, Scheinin, T. M., see Pekkarinen, 890 918,924 A, 912, 930 - see Morgan, C. D. 875, 892 Scales, B., McIntosh, D. A. D. Scheline, R R 877, 895 - see Pare, C. M. B. 854, 862, 398,421,458 - Midtvedt, T. 877, 895 893 Schacht, U., Schultz, G., Senft, - see Dacre, J. C. 858, 877, 886 - see Ruthven, C. R. J. 874, G. 259, 267 Schenken, I., Bueker, E. D. 894,913,920,921,930 Schachter, M., see Bhoola, K. D. 819,841 - see Smellie, J. M. 852, 896 99,105 Scheving, L. E., Harrison, W. - see Youdim, M. B. H. 6, 15, Schafer, E. A., see Oliver, G. H., Gordon, P., Pauly, J. E. 850,899 796,811 119,182 Sandow, A., see Eberstein, A. Schafer,H.,seeJurna,1. 796,808 Schiefthaler, T., see Hertting, 800,806 Schaefer, J. M., see Van Orden, G. 125, 160, 177, 212, 224, Saner, A., Thoenen, H. 829, 841 L. S. 52, 56, 60, 67, 70, 78 813, 815, 816, 838 Sanger, F., see Lamer, J. 401, Schaeffer, L. D., Chenoweth, Schiffer, I. M., see Cotzias, G. 452 M. Dunn, A. 371, 405, 458 C. 4, 13, 846, 857, 860, 864, Sanghvi, I., Murayama, S., Schaepdryver, A. F. de 903, 931 885 Smith, C. M., Unna, K. R. - Preziosi, P., Van der Schild, H., see Gaddum, J. H. 705,723 Stricht, J.182 2,13 Sankoff, I., Sourkes, T. L. 913, - Taquini, A. C. jr., Bernard, Schild, H. O. 288, 290, 334 921,931 P., Heymans, C. 132, 161, - see Arunlakshana, O. 291, - see Sourkes, T. L. 874, 897 166,182 330 68 Hdb. expo Pharmakol., Vol. xxxm 994 Author Index

Schildkraut, J. J., Schanberg, Schneider, J. A., Plummer, A. Schiimann, H.-J., Schmidt, K., S. M., Breese, G. R., Kopin, J., Earl, A. E., Gaunt, R. Philippu, A. 67, 77 I. J. 500, 535 517,535 - see Burger, A. 205, 220 - see Klerman, G. L. 862, 890 Schneider, K., see Matussek, N. - see Haag, H. W. 241, 264, - see Schanberg, S. M. 467, 862,892 914,927 468,499,534 Schnieden, H., Williams, T. - see Holland, W. C. 233, 234, Schiller, D., see Shahab, L. 399, 855,895 265 458 Schnur, J. A., see Chase, T. N. - see Holtz, P. 132, 177 Schimke, R. N., Hartmann, W. 860,885 - see Kleinschmidt 909, 928 H. 901, 931 Schoen, M. S., see Saelens, J. K. - see Kroneberg, G. 234, 266, -- Prout, T. E., Rimoin, D. 112,134,149,182 498,529 L. 901, 931 Schoenbaum, E., see Derry, D. - see Philippu, A. 205, 227, Schirger, A., see Zimon, R. P. M. 130,174,408,446 251, 252, 253, 255, 267, 498, 912,933 - see Steiner, G. 409, 459 533,539,587,590,591,614, Schlegel, G. G. 901, 931 Schoenfeld, C. D., see Harris, 615,625,626,627,637,638, Schlender, K. K., Wei, S. H., W. S. 491, 527 641,642,657 Villar-Palasi, C. 401, 458 SchOnhiifer, P. S., Tissad, A. H. Schull, L. G., see Riddell, D. H. Schlossberg, T., see Sawyer, M. 213,229 901,930 E. 813, 841 SchOpf, J., see Hiirtnagl, H. Schultz, E. J., see Merritt, J. H. Schlossmann, H., see Blaschko, 600 H. 5, 12, 271, 280, 620, 652 192,226 Scholfield, C. N., see Brown, D. Schultz, G., see Schacht, D. Schlossmann, K., see Krone• A. 697, 716 berg, G. 750, 759 259,267 Scholfield, P. C., see Davey, M. - see Senft, G. 367,422,423, Schmid, E. 912, 931 J. 704, 713, 716, 776, - Bachmann, K., Heynen, H. 805 458 Scholz, R., see Williamson, J. Schultz, R. B., see Parra, A. P., Graf, N., Krautheim, J. R. 371, 373, 374, 462 914,931 435,455 Schoner, W., see Seubert, W. Schwab, A., see Furchgott, R. - see Tiedge, F. 923, 933 373,458 Schmid, F. G., see Grodsky, G. F. 212, 223, 303, 332, 634, M.420,448 Schoolar, J. C., see Roth, L. J. 654, 730, 731, 757 Schmidt, J. 482, 535 534 Schwab, R. S. 870, 895 - Flthse, C. 505, 535 Schott, H. F., Clark, W. G. 188, - Amador, L. V., Lettvin, J. Schmidt, J. L., Fleming, W. W. 228,867,895 Y. 863, 895 337,344,346,361,833,834, Schramm, M. 424, 458 - England, A. C., jr., Poskan• 841 - Bdolah, A. 425, 458 zer, D. C., Young, R. R. Schmidt, K., see Schiimann, H. - see Amsterdam, A. 423, 441, 869, 895 J.67,77,623,627,637,644, 589,597,605 - see Barcroft, H. 494, 520 658 - see Babad, H. 424, 442 Schwartz, D. E., Burkard, W. Schmidt, R. F., see Hubbard, - see Bdolah, A. 424, 442 P., Roth, M., Gey, K. F., J. I. 692, 720, 789, 802, - see Feinstein, H. 424, 447 Pletscher, A. 499, 535 808 - see Salomon, Y. 424, 458 Schwartz, I. L., see Dousa, T. - see Jaenig, W. 688, 720 Schroeder, D., see Ordy, J. M. 433,446 Schmiterliiw, C. G. 129, 182, 160,181 Schwartz, W. F., see Sacks, O. 188, 191, 228, 852, 895 Schroeter, G. A., see Golden, R. W. 861, 865, 894, 895 Schmitt, F. 0., Samson, F. E. L. 868, 887 Schwarz, G. A., Fahn, S. 862, 602,615 DeSchryver, C., Mertens-Stryt• 869,895 - see Bloom, F. E. 5, 12 hagen, J., Becsei, I., Lam• Schweissguth, O. 920, 931 Schmitt, H., Gonnard, P. 742, merant, J. 159, 170, 182 - see Amar-Costesec, A. 904, 752, 760 Schubert, J., Nybitck, H., Sed• 917,924 - Schmitt, H. 337, 361 vall, C. 499, 500, 535 Schubert, P., Ladisch, W. 467, - see La Brosse, E. H. 917, - Petillot, N. 646, 647, 651, 919,928 658 535 - see Schmitt, H. 337, 361 Schiimann, H.-J. 4, 15, 117, Schweitzer, A., Wright, S. 515, Schnaitman, C., Erwin, V. G. 120, 125, 129, 132, 161, 165, 516,535 Greenawalt, J. W. 6, 15 166,167,168,182,188,228, Scian, L. F., Westermann, C. Schneider, F., see Maxwell, R. 239,249,258,261,267,541, D., Verdesca, A. S., Hilton, A. 354, 360, 727, 760 548, 550,551, 553, 560, 600, J. G. 915, 931 Schneider, F. H. 551, 587, 589, 615,902,905,906,907,908, Scopes, J. W., Tizard, J. P. M. 590,615 909,931 485,535 - Smith, A. D., Winkler, H. - Grobecker, H. 192,228 Scott, C. C., see Chessin, M. 34, 44, 540, 555, 557, 558, -- Schmidt, K. 619, 623, 194,221 560,562,587,592,615 627,637,644,658 Scott, H. W., Ridell, D. H., - see Blaschko, H. 5, 12, 68, - Giither, W. 730, 760 Brockman, S. K. 901, 931 72, 250, 257, 262, 540, 555, - Philippu, A. 242, 245, 259, - see Lance, E. M. 913, 928 557,576,606 267 Scott, J. A. 852, 895 Author Index 995

Scott, M. J., see Daly, M. de B. Sekeris, C. E., see Herrlich, P. Shanks, R. G., see Dunlop, D. 584, 607, 764, 805 913, 921, 927 320,331 Scudder, C. L., Karczmar, A. - see Karlson, P. 99, 107 Shanta, T. R., see Manocha, S. G., Everett, G. M., Gibson, Selberis, W. H., see Arnold, A. L. 662, 722 J. E. Rifkin, M. U8, 182 320,321,330,441,441 Shapiro, A. P., see Sapira, J. P. Sealock, R. R. 852, 895 Sell, J., see Werle, E. 619, 660, 901,931 Sears, M. L., Barany, E. H. 852,899 Shapiro, H. 797, 800, 811 817,841 Sellers, E. A., see Steiner, G. Shapiro, S. H., see Beyer, K. - Gillis, C. N. 817, 841 409,459 H. 270, 280 - see Nishida, S. 52, 76 Sellinger, O. Z., see Beaufay, Share, N. N., Melville, K. I. - see Waltman, S. 813, 816, H. 249, 262 494,535 822,843 Selvaratnam, I., see Weiner, N. Sharkey, J., see CaIne, D. B. Seaton, J. F., see Harrison, T. 640,660 884 S. 132, 177, 912, 915, 927 Selye, H., Veilleux, R., Cantin, - see Hunter, K. R. 861, 890 Seay, P. H., see Moffett, R. B. M.425,458 Sharma, V. N., see Sogani, R. 506,532 Semba, T., Civen, M. 867, 896 K. 646, 658 Sedden, C. B., Walker, R. J., Senft, G., Schultz, G., Munske, Sharman, D. F. 123, 170,183, Kerkut, G. A. 82, 93, 94, K., Hoffman, M. 367, 458 896 108 - Sitt, R., Losert, W., - Poirier, L. J., Murphy, G. - see Kerkut, G. A. 82, 89, Schultz, G., Hoffmann, M. F., Sourkes, T. L. 847, 896 94,95,96,107 367,422,423,458 - Vanov, S., Vogt, M. 159, - see Walker, R. J. 97, 98, 109 - see Schacht, U. 259, 267 183,272,281 Sedvall, G. 218, 228 Senoh, S., Creveling, C. R., - Vogt,M. 148,183 - Kopin, I. J. 194, 228, 235, Udenfriend, S., Witkop, B. - see Callingham, B. A. U7, 267, 813, 816, 822, 828, 841 823,841 147,173 - Weise, V. K., Kopin, I. J. - Daly, J., Axelrod, J., Wit• - see Dagirmanjian, R. 495, 639,658 kop, B. 857, 896 496,523 - see Fuxe, K. 131, 176, 831, - Witkop, B. 823, 842 - see Holzbauer, M. 854 833,838 -- Creveling, C. R., Uden- - see Kelly, M. 132, 178 - see Kopin, I. J. 639, 640, friend, S. 842, 856, 896 - see Laverty, R. U2, U5, 641,655 - see Axelrod, J. 270, 279 118, 119, 120, 148, 149, 152, - see Nyback, H. 467, 468, Seraydarian, K., see Hassel• 153,154,156,159,179,787, 499,533 bach, W.245,264 809,823,826,839,855,891 - see Rosell, S. 210, 228, 87l, Serck-Hansen, G., see Helle, - see LeBlanc, J. 132,179 894 K. B. 250, 264, 592, 610 - see Murphy, G. F. 873, 893 - see Schubert, J. 499, 500, Serrano, L., see Marques, M. - see O'Keeffe, R. 148, 154, 535 142,180 181,855,893 - see Strandberg, K. 165, 184 Serrano, P. 875, 896 Sharpe, L. G., Myers, R. D. - see Wurtman, R. J.120, 185 Sestini, M. G., see Manara, L. 489,490,535 Segal, D. S., Whalen, R. E. 866, 500,531 - see Myers, R. D. 489, 532 895 Seubert, W., Henning, H. V., Sharpless, S. 47l, 478, 514, 535 Segal, H. L., see Mersmann, H. Schoner, W., L'age, M. 373, Sharpstone, P., see Parkes, J. J. 370, 454 458 D. 862, 893 Segall, M. M., see Hull, D. 417, Sevy, R. W., see Shindler, R. Shaw, F. H. U2, 183 450 160,183 Shaw, K. N. F., Gutenstein, M., Segura, E. T., Biscardi, A. M. Seydoux, J., see Girardier, L. Jepson, J. B. 877,896 139,183 409,448 - Lieberman, E., Koch, R., -- Apelbaum, J. U5, 183 Seyffert, W. A., jr., Madison, Donnell, G. N. 921, 931 - see Donoso, A. O. U5, 174 L. L. 422, 458 - McMillan, A., Armstrong, Seidehamel, R. J., Patil, P. N., - see Madison, L. L. 422, 453 M. D. 270, 281, 874, 896 Tye, A., Lapidus, J. B. 746, Shafrir, E., see Gorin, E. 388, - see Armstrong, M. D. 6,11, 747, 760 389,448 270,272,279,848,881,912, Seiden, L. S., Carlsson, A. 496, - see Gutman, A. 388, 448 924 535 Shah, N. S., Kamano, A., Glis• Shea, S. M., Karnovsky, M. J. - Peterson, D. D. 503, 504, son, S., Callison, D. 852, 896 602,615 535 Shahab, L., Lishajko, F., v. Shealy, C. N., Weeth, J. B., - see Krantz, K. D. 504, 529 Euler, U. S. 201, 207, 228 Mercier, D. 870, 896 Seifter, J., see Clymer, N. V. - Wollenberger, A., Haase, Shein, H. M., Wurtman, R. J. 512,523 M., Schiller, U. 399, 458 429,458 Seitelberger, F., see Bernhei• Shand, D. G. 695, 723 - see Axelrod, J. 429, 430, mer, H. 848, 856, 883 - see Quilliam, J. P. 7l2, 723 431, 442, 823, 836 Sekeris, C. E., Herrlich, P. 875, Shanes, A. M. 723 - see Wurtman, R. J. 431, 895,913,931 Shanfeld, J., Frazer, A., Hess, 462,823,844 - Karlson, P. 99, 108, 853, M. E. 392, 395, 458 Shekelle, R. B., see Klawans, 876,896 - see Hess, M. E. 399, 449 H. L., jr. 869, 872, 890 6S· 996 Author Index

Shelp, W. D., see Hokin, M. R Shore, P. A., Mead, A. R., Sigwald, J., Raymondeaud, C. 611 Kuntzman, R. G., Spector, 864,896 Shepherd, D. M., West, G. B. S., Brodie, B. B. 272, 281 Sih, C. J., Foss, P., Rosazza, J. 18, 22, 44, 122, 123, 124, - Olin, J. S. 112,183 Lemberger, M. 852, 896 143, 158,183,185, 232, 267, - see Berti, F. 500, 520, 622, Silver, M., see Blaschko, H. 5, 903, 905, 906, 931 623,652 12, 68, 72, 250, 257, 262, Sheppard, H., Burghardt, C. - see Brodie, B. B. 486, 498, 540,555,557,576,606 433,459 521 - see Comline, R S. 416, 445 Sheps, S. G., see Cremer, G. M. - see Crout, J. R. 625, 630, Silverman, L., Dahlin, D. C., 915,925 631,632,633,635,641,653 Tyee, G. M., Stickler, G. B. - see Levit, S. A. 929 - see Giachetti, A. 208, 223, 918,931 - Maher, F. T. 914, 915, 931 352, 358, 621, 622, 654 Silvestrini, B., see Longo, V. G. - Tyee, G. M., Flock, E. V., - see Govier, W. C., 731, 476,530 Maher, F. I. 911, 912, 931 758 Simard, S., see Genest, J. 130, - see Zimon, R. P. 912, 933 - see Kuntzman, R 150, 179 169,176 Sherif, M. A. F. 762, 811 - see Murad, J. E. 622, 656 ~imek, J. 855, 896 Sherrod, T. R, see Bristow, M. - see Pletseher, A. 5, 15 Simmonds, M. A., Gillis, C. N. 310, 312, 313, 323, 324, 330 - see Spector, S. 272, 282, 747,748,749,760 Sherwood, S. L.470,535 505,536, Simmons, C., see Goldstein, M. - see Feldberg, W. 470, 471, - see Sugrue, M. F. 622, 623, 112, 170, 177 525 659 Simon, P., see Boissier, J. R Shideman, F. E., see Bhagat, Shorr, S. S., Bloom, F. E. 52, 496,505,521 B. 354, 355, 357 70,77 Simona, B., see DeAjuriaguerra - see Campos, H. A. 217, 220 Shulgin, A. T., Sargent, T., J.877 - see Ignarro, L. J. 117, 143, Naranjo, C. 866, 896 Simpson, F. 0., see Devine, C. 178 Shulman, J., see Kim, T. S. E. 53, 56, 58, 73 - see Lee, W. C. 355, 359, 764, 406,451 Simpson, L. L. 581, 590, 615 809 Shumway, W. 115, 183 Sims, J. A., see Kuttner, R Shimamoto, K., see Toda, N. Shute, C. C. D., see Lewis, P. R 465,529 494,495,536 34,38,43,585,612 Sims, M., see Bradham, L. S. Shimazu, T. 371, 459 Shy, M., Drager, G. 855, 896 382,427,443 - Amakawa, A. 370, 371, 459 Sidman, R. L., Perkins, M., Simson, J. V. 424, 459 Shimizu, H., Creveling, C. R., Weiner, N. 130, 170, 183, Sinclair, L., see Anthony, P. P. Daly, J. W. 427, 459 815,842 917,919,924 - Daly, J. W., Creveling, C. - see Weiner, N.130, 170,185 Singer, J. J., see Goldberg, A. R.427,459 Siegel, G. J., see Mones, R J. L.401,402,448 - see Creveling, C. R 857, 861, 862, 866, 869, 892 Singer,S.J.,seeLenard,J.48,75 886 Siegel, W. C., see Pertsemlidis, Singh, P., see Barbeau, A. 858, Shimizu, N., see Ishii, S. 61,75, D. 901, 913, 930 882 77 Siegfried, J. 863, 865, 896 - see Poirier, L. J. 847, 853, - see Matsuoka, M. 61, 76 - see Krayenbiihl, H. 863, 868,893,894 Shimosato, S., see Etsten, B. E. 869,891 - see Sourkes, T. L. 847, 860, 911,925 Siegman, M., see Ostlund, E. 897 Shin, Y. H., see Lee, W. C. 355, 134,181 Sipple, J. H. 901, 931 359 Siegrist, G., Dolivo, M., Du• Sirness, T. B., see Naess, K. Shindler, R., Harakal, C., Sevy, nant, Y., Foroglov-Kera• 798,800,810 R. W. 160,183 meus, C., de Ribaupierre, Sitt, R, see Senft, G. 367, 422, Shinebourne, E. A., Hess, M. L., F., Roullier, C. 52, 70, 77, 423,458 White, R. J., Hamer, J. 786,787,811 Sjoberg, N.-O. 127, 164, 183 398,459 - Ribaupierre, F. de, Dolivo, - see Falck, B. 133, 176 - see Hess, M. L. 398, 449 M., Rouiller, C. 22, 39, 44 - see Hakanson, R 133, 177 Shipley, R E., Tilden, J. H. Siekert, R G., see Fuller, A. M. - see Owman, C. 127, 164,181 111,183 923,926 - see Rosengren, E. 127, 164, Shooter, E. M., see Varon, S. Sierra de la Gomez Alonso, see 182 819,843 Trendelenburg, U. 301, 334, Sjoqvist, F. 786, 811 Shore, P. A. 112, 161, 165, 166, 337,341,343,344,345,351, - Taylor, P. W., jr., Titus, E. 167,183,498,535 362,648,659,737,747,761, 821,842 - Alpers, H. S. 622, 658 832,833,843 - Titus, E., Michaelson, I. A., - Busfield, D., Alpers, H. S. Siess, E., see Wieland, O. 394, Taylor, P., Richardson, K. 497,535,619,621,622,625, 461 C. 56, 77, 821, 842 628, 637, 638, 658 Sigg, E., Oche, S., Gerard, R - see Buckley, G. 662, 716 - Cohn, V. H., jr., Highman, W.515,535 - see Hamberger, B. 662, 719, B., Maling, H. M. 159, 169, - see Gyermek, L. 705, 718 820,821,822,830,838 183 Siggins, G. R, Bloom, F. E. 53, - see Norberg, K.-A. 682, 723, - Giachetti, A. 209, 228 M, 56, 58, 60, 77 783,787,811 Author Index 997

Sjoercisma, A. 4, 15, 272, 280, Skelton, C. L., Levey, G. S., Smith, C.B., DewB, P.B. 496, 535 851, 896, 914, 931 Epstein, S. E. 395, 396, 459 - Trendelenburg, U., Langer, - Engelman, K., Spector, S., - see Levey, G. S. 392, 395, S. Z., TBai, T. H. 157, 183, Udenfriend, S. 851, 896, 397,453 734,760,815,817,818,833, 916,931 Skinner, S. L., see Matz, L. R. 842 -- Waldmann, T. A., 25,43 - see Antonaccio, M. J. 752, Cooperman, L. K., Ham• Skipski, V. P., Peterson, R. F., 756 mond, W. G. 912, 931 Barclay, M. 592, 615 - Bee Steinberg, M. I. 339, 361 - Leeper, L. C., Terry, L. L., Skoglund, C. R. 516, 517, 535 Smith, C. M., Bee Sanghvi, I. Udenfriend, S. 902, 904, 931 - Bee Bernhard, C. G. 515, 520 705,723 - Lovenberg, W., Engelman, - see Biilbring, E. 516, 521 Smith, D. E., see Thomson, J. K., Carpenter, W. T., jr., Skok, V. I. 665, 685, 724 F. 411, 412, 460 Wyatt, R. J., Gessa, G. L. Skultety, F. M. 489, 535 Smith, D. F., see Grodsky, G. 866,896 Slangen, J. L., Miller, N. E. M. 420, 448 -- Oates, J. A., Crout, J. R. 490,510,535 Smith, D. S., see Jarlfors, U. Udenfriend, S. 189, 228 Slarotinek, A., De la Lande, I. 603,611 - Studnitz, W. von 626, 658 S., Head, R. 901, 932 Smith, D. W., see Copps, S. G. - Vendsalu, A., Engelman, K. Slater, I. H., see Powell, C. E. 852,885 619,658 285,334,814,841 Smith, E. R. B., see Weil-Mal• - Bee Dairman, W. 195, 221, Smalley, K. N. 109 herbe, H. 903, 933 234,263 Smellie, J. M., Sandler, M. 852, Smith, I., Kellow, A. H. 850, - Bee DeQuattro, V. L. 851, 896 851,855,896 886 Smets, W., see Mahaux, J. E. -- Hanington, E. 850, 896 - Bee Cooper, T. 815, 837 912,929 -- Mullen, P. E., Haning- - see Crout, J. R. 902, 903, Smiley, R. L., Bee Schayer, R. ton, E. 850, 896 905, 911, 912, 916, 922, 925 W.270,272,281 Smith, J. L., see Buhs, R. P. - Bee Engelman, K. 914, 915, Smirnow, A. 783, 784, 811 620,652 925 Smith, A. A., Fabrykant, M., Smith, J. M., see Mayer, S. E. - Bee EvartB, E. V. 272, 280 Kaplan, M., Gavitt, J. 880, 399,454 - Bee Gillespie, L. 620, 654 896 Smith, J. S., Brandon, S. 848, - see Gordon, R. 194, 223, Smith, A. D. 26, 44, 242, 248, 896 234,237,264 250,251,252,268,539,543, Smith, P. 876, 896 - see Govier, W. C. 423, 448 544,546,551,576,581,584, - Bee Coward, R. F. 903, 925 - see Horwitz, D. 850, 863, 586,598,601,603,604,615 - see Kelleher, J. 912, 928 869,889 - DePotter,W.P.555,589,616 - see Robinson, R. 912, 913, - see Jequier, E. 879, 890 -- Moerman, E. H., De 930 - see La Brosse, E. H. 912, Schaepdryver, A. F. 557, Smith, R. A., Whitehead, T. 928 575,576,578,579,580,581, P., Morris, L., Williams, H. - see Levine, R. .J. 192, 226, 588,616 P. 919, 932 636, 639, 655, 850, 891 - Winkler, H. 5, 26, 44, 248, Smith, R. E., Farquhar M. G. - see Levitt, M. 226, 234, 237, 249,250,251,268,539,551, 27,44,601,616 266,501,530,816,840 556,562,580,592,594,601, - Horwitz, B. A. 408, 416, - Bee Oates, J. A. 191, 227, 616,620,634,635,856,906, 418,459 618,657 907,915,923,932 -- Imai, Y. 417, 459 - Bee Pettinger, W. A. 619, - see BlaBchko, H. 5, 12, 26, - Roberts,J.C.411,459 657 40, 68, 72, 250, 251, 257, - see Cameron, I. L. 408, 416, - see Sato, T. L. 913, 931 262,540,555,557,576,592, 444 - see Spector, S. 187, 189, 593,601,606,906,907,908, - Bee Hittelman, K. J. 414, 190,191,194,196,228,235, 909,911,924 450 268,501,502,536,637,639, - Bradbury, S. 68, 73 - see Horwitz, B. A. 409, 413, 658,851,897 - see DePotter, W. P. 214, 417,450 - Bee Studnitz, W. v. 920, 921, 217,221,574,576,578,579, - Bee Imai, Y. 417, 450 932 588,590,604,608 - Bee Roberts, J. C. 411, 457 - see Udenfriend, S. 85, 109 - Bee Schneider, F. H. 34, 44, Smith, R. L. 878, 896 - see Yamori, Y. 854, 899 540,555,557,558,560,562, - Bee Paoletti, R. 170, 181 Sjostrand, N.-O. 116, 126, 143, 587,592,615 -- Brodie, B. B. 170, 183 163, 183, 815, 842 - Bee Strieder, N. 908, 932 Smith, R. W., McCann, S. M. - Swedin, G. 163, 183 - see Winkler, H. 539, 540, 489,535 - Bee Ryd, G. 126, 182 542,555,558,559,565,592, Smith, W. J., Bee Kirshner, N. SjoBtrom, R., see Roos, B.-E. 593,600,617,903,904,908, 68, 75, 213, 225, 244, 246, 846,894 916,933 249,250,258,265,540,555, Skala, J., Barnard, T., Lind• Smith, C. B. 149,183,278,281, 557,560,562,565,587,595, berg, O. 411, 416, 459 298,334,337,361,646,648, 612 - see Barnard, T. 411, 417, 651,658,730,752,760,834, - see Sage, H. J. 34, 44, 540, 442 842 555,615 998 Author Index

Smithwick, R. H., see Greer, Solomon, H. M., see Abrams, Southgate, J., see Challacombe, W. E. R. 901, 927 W. B. 873, 881 D. N. 850, 885 Smuckler, E. A., see Robino• - see Leon, A. S. 873, 891 - see Collins, G. G. S. 881, 885 vitch, M. R. 426, 457 Somani, P., Lum, B. K. B. 314, - see Contractor, S. F. 871, Smyth, G. E., see Kremer, M. 334 885 847,891 Somlyo, A. P., see Somlyo, A. - see Sandler, M. 850, 851, Smythies, J. R. 845, 897 V. 731, 760 878,895 - Johnston, V. S., Bradley, R. Somlyo, A. V., Woo, C. Y., Souto, M., see Couch, E. F. 563, J., Benington, F., Morin, R. Somlyo, A. P. 731, 760 607 D., Clark, L. C. jr. 866, 897 Sommelet, J., see Faivre, G. Souverijn, J. H. M., see Van - Levy, C. K. 478, 535 9lI,926 den Bergh, S. G. 415, 460 Snipes, R. L., Thoenen, H., Sommer, A., see Poll, H. 89, Spann, J. F., jr., Chidsey, C. A., Tranzer, J. P. 842 108 Braunwald, E. 159, 183 - see Tranzer, J. P. 46, 48, 56, Sommer, S., see Miiller-Calgan, Spano, P. F., Vargui, L., Cra• 64,67,77,78,823,824,828, H. 848, 893 bai, F., Congiu, S., Gessa, 843 Sommer, S. R., Novin, D., R., Gessa, G. L. 170, 183 Snyder, D. W., see Gebber, G. Levine, M. 489, 535 Spector, N. H., Brobeck, J. R., L. 706, 707, 718 Sonnenblick, E. H., Stam, A. Hamilton, C. L. 491, 536 Snyder, R., see Vogel, W. H. C., jr. 397, 459 Spector, S., Gordon, R., 853, 854, 867, 868, 898 - see Henderson, A. H. 398 Sjoerdsma, A., Udenfriend, Snyder, S., Fischer, J., Axelrod, 449 S. 194, 228, 235, 268, 639, J. 271,282, 822, 842 Sonneville, P. F. 880, 897 658 - see Fischer, J. E. 67, 74, - see Goldberg, L. I. 863, 887 - Mata, R. 0., Sjoerdsma, A., 814,837 Sonninen, V., see Hyyppa, M. Udenfriend, S. 501, 536 - see Musacchio, J. M. 193, 866,890 - Melmon, K., Lovenberg, 201,227,503,532 - see Rinne, U. K. 153,182, W., Sjoerdsma, A. 189, 228 Snyder, S. H., Axelrod, J., 861, 872, 875. 894 - Prockop, D., Shore, P. A., Wurtman, R. J., Fischer, J. Sorensen, B., see Laursen, T. Brodie, B. B. 272, 282, 505, E. 823, 842 928 536 -- Zweig M. 901, 932 Soteres, P., see Duke, W. W'. - Shore, P. A. 282 - Coyle, J. T. 873, 897 922,923,925 -- Brodie, B. B. 505, 536 - Green, A. I., Hendley, E. D. Sourkes, T. L. 188, 191, 228, - Sjoerdsma, A., Udenfriend, 500,535 618,639,658,814,842,874, S. 190, 191, 228, 501, 502, - Taylor, K. M., Coyle, J. T., 897 536, 637, 658, 851, 897 Meyerhoff, J. L. 854, 865, - Denton, R. L., Murphy, G. -- ZaItz man-Nirenberg, P., 897 F., Chavez. B., Saint Cyr, Levitt, M., Udenfriend, S. - see Coyle, J. T. 499, 523, S. 874, 897, 920,921, 932 187,196,228 865,870,886 - Heneague, P., Trano, Y.4, 15 - see Costa, E. 787, 791, 805 - see Glowinski, J. 218, 223, - Missala, K. 867, 897 - see Dairman, W. 195, 221, 467,468,526 - Murphy, G. F. Ill, 183 234,263 - see Horn, A. S. 870, 889 -- Chavez, B., Zielinska, - see Gordon, R. 194, 223, - see Taylor, K. M. 865, 897 ~I.497, 536, 636,658 234,237,264 Sobel, B. E., Dempsey, P. J., -- Rabinovitch, A. 189, - see Levitt, M. 226, 234, 237, Cooper, T. 392, 459 191, 228, 878, 897 266, 501, 530, 816, 840 Sobel, C., see Jacobs, L. S. 912, - Pivnicki, D., Brown, W. T., - see Maling, H. M. 272, 281, 928 Wiseman-Distler, M. H., 505,530 Soeda, H., see Koketsu, K. 695, Murphy, G. F., Sankoff, I., - see Pettinger, W. A. 619, 696,721 Saint Cyr, S. 874, 897 657 - see Nishi, S. 664, 674, 675, - Poirier, L. J. 847, 897 - see Shore, P. A. 272,281 676, 683, 722, 685, 688, 690 -- Singh, P. 847, 860, 897 - see Sjoerdsma, A. 851, 896, Soffer, L., see Korol, B. 648,655 - see Barbeau, A. 855, 860, 916,931 Sogani, R. K., Sharma, V. N. 869,879,882 - see Udenfriend, S. 497, 501, 646,658 - see Bedard, P. 851, 882 503,537,619,627,637,639, Sokal, J. E., Sarcione, E. J., - see Drujan, B. D. 121, 170, 660 Henderson, A. M. 367, 371, 174 Spencer, S. J., see Robins, E. 459 - see Lancaster, G. 847, 868, 854,894 Solandt, D. Y., see Bronk, D. 891 Speth, O. C., see Buhs, R. P. W. 663, 682, 690, 716 - see Murphy, G. F. 227 620,652 Sol cia, E., Sampietro, R., Ca• - see Papeschi, R. 859, 893 - see Prescott, L. F. 620, 658 pella,C.48,77 - see Poirier, L. J. 154, 181, Spiegel, E. A., see Wycis, H. T. Solier, M., see Beauvallet, M. 847, 856, 868, 894 869,899 lI8,172 - see Sankoff, I. 913, 921, 931 Spiegel, H. E., see Dengler, H. Solomon, H. M., Spirt, N. M., - see Sharman, D. F. 847, 896 J. 203, 208, 209, 213, 221 Abrams, W. B. 873, 879, - see Wiseman-Distler, M. H. - see Morgan, J. P. 871, 874, 897 864,899 876,892 Author Index 999

Spiegel, H. E., see Titus, E. O. Staley, N. A., Polesky, H. F., Steinman, A. M., see Barchas, 212,229 Bensch, K. G. 919, 920, J. D. 119, 172 Spiers, A. S. D., see Caine, D. 932 Stellar, S., Mandell, S., Waltz, B. 861, 863, 865, 873, 884 Stalmans, W., see De Wulf, H. J. M., Cooper, I. S. 861, 865, Spiro, D., see Tannenbaum, M. 370,446 897 909,932 Stam, A. C., jr., see Sonnen• Stenfio, J., see Falck, B. 125, Spirt, N. M., see Solomon, H. blick, E. H. 397, 459 128,176 M. 873, 879, 897 Stamenovic, B. A., see Jenkin• Stephens, Welsh, 81, 91 Spitzer, J. J., McElroy, W. T., son, D. H. 800, 801, 808 Stephenson, J. D., see Marley, jr. 373, 459 Staneloni, R., Piras, R. 403, E. 47l, 474, 475, 485, 488, Spjut, H. J., see Brown, H. D. 459 489,491,495,506,508,510, 433,448 - see Piras, R. 402, 403, 404, 512,513,515,516,531,873, Spoerlein, M. T., see Van der 405,455 892 Wende, C. 857, 898 Stanley, G. H. S., see Blaschko, - see Wurtman, R. J. 874, 899 Spooner, C. E., Winters, W. D. H. 188, 220, 878, 883, Stephenson, R. P. 288, 289, 334 464,496,497,505,536 Stanley, S., see Vaughan, M. Sterescu -Volanschi, M., see -- Mandell, A. J. 465, 512, 388,461 Floru, R. 478, 525 536 Stanton, H. C., see Mayfield, E. Stern, D. N., Maling, H. M., - see Mandell, A. J. 501, 531 D., jr. 425, 426, 454 Altland, P. D., Brodie, B. Sporrong, B., see Ehinger, B. Staszewska-Barczak, J., Vane, B. 814, 842 730, 757, 778, 780, 781, 806 J. R. 914, 915, 932 - see Maickel, R. P. 814, 840 Spratt, J. S., jr., see Brown, H. Staub, M., see Barnett, A. 339, Stern, G. 846, 897 D. 433, 443 357 Stern, G. M., see Bonham Car• Spratto, G. R., Miller, J. W. Staub, M. S., see Wong, K. K. ter, S. 851, 883 127,183 420,421,462 - see CaIne, D. B. 861, 863, Sprenger, E., see Lindmar, R. Stauffacher, W., see Lambert, 865,873,884 621,625,630,633,634,635, A. E. 421, 452 - see Hunter, K. R. 861, 863, 637, 642, 643, 648, 650, 656 Stavorski, J. M., see Stone, C. 837, 869, 870, 880, 889, 890 - see Muscholl, E. 351, 360, A. 344, 361, 647, 659, 823, Stern, R., see Posner, J. B. 401, 621,625,637,644,646,648, 827,842 402,456 657 - see Torchiana, M. L. 635, Stickler, G. B., Flock, E. v. 920, Spriggs, T. L. B., see Ester• 659 932 huizen, A. C. 52, 56, 58, 74, Steen, B., see Anden, N. E. 865, - Hallenbeck, G. A., Flock, E. 729, 757, 779, 806 866, 872, 874, 875, 881 v.932 - see Graham, J. D. P. 53, 56, Stefano, F. J. E., see Leitz, F. - see Silverman, L. 918, 931 74, 584, 610, 780, 807 H. 213, 226 Stickney, J. I., see Lucchesi, B. - see Lever, J. D. 46, 53, 56, Steg, G. 861, 897 R. 314, 333 58, 75 - see Anden, N. E. 865, 866, Stilling, H. 22, 44 Springer, A., see Aigner, A. 504, 872, 874, 875, 881 Stitzel, R. E., Lundborg, P. 518 Stehbens, W. E., see Biscoe, T. 217,228 Sprinkle, T. J., see Greer, M. J.23,40 - see Almglen, O. 621, 652 913, 921, 927 Stehle, R. L., Ellsworth, H. C. - see Carlsson, A. 620, 645, 653 Sproull, D. H., see Rocha e 2,15 - see Lundborg, P. 243, 245, Silva, M. 493, 534 Steiert, B., see Masoro, E. J. 259,266,622,625,645,656 Sreebny, L. M., see Robino• 404,454 Stitzel, R. E., see Urquilla, P. vitch, M. R. 426, 457 Steiker, D. D., see Young, R. B. R. 315, 316, 335, 348, 362, Stabrovskii, E. M. 114, 134, 920,921,933 745, 761 135, 136, 138, 184 Steinberg, D., see Challoner, D. Stjarne, L. 50, 77, 189, 191, - see Leibson, L. G. 117,179 R. 394, 444 194,205,228,229,232,233, Stacey, R. S. 853, 897 - see Crespin, S. R. 422, 445 234,235,236,240,241,245, - see Pare, C. M. B. 854, 856, - see Greenough, W. B. 422, 249,252,253,255,257,258, 898 448 259,268,468,498,536,539, Staehelin, H., see Haefely, W. - see Vaughan, M. 388, 461 544,546,549,550,581,582, 704,708, 719 Steinberg, M., see Hilton, J. G. 616, 914, 923, 932 - see Thoenen, H. 7l2, 724 684,719 - von Euler, U. S. 740, 760 Staehelin, M., see Maier, R. Steinberg, M. I., Smith, C. B. -- Lishajko, F. 258, 268, 626,656 339,361 352, 361, 906, 907, 908, 932 - see Maitre, L. 188, 189, 218, Steiner, G., Cahill, G. F., jr. - Hedqvist, P. 240, 268 226,619,623,625,626,627, 409,459,485,536 -- Bygdeman, S. 568, 569, 636,637,647,656 - Johnson, G. E., Sellers, E. 616 Staubli, W., see Suter, E. R. A., Schonbaum, E. 409, 459 -- Lagercrantz, H. 217, 416,460 - Loveland, M., Schonbaum, 229,249,268,574,616 Stafford, A. 398, 459, 748, 760 E. 409, 459 - Lishajko, F. 189, 193, 229, - see Born, G. V. R. 132, 172 - see Derry, D. M. 130, 174, 232,233,236,268,498,536, - see Foo, J. W. 307, 331 408,446 616,639,658 1000 AuthOl' Index

Stjarne, L., Lishajko, F., Roth, Strack, 1., see Eisenstein, A. B. Sugrue, M. F., Shore, P. A. 622, R.II.194,195,229,236,268 373,446 623,659 - Roth, R. II., Bloom, F. E., Strandberg, K., Sedvall, G., - see Govier, W. C. 731, 758 Giarman, N. J. 53, 68, 77, Midtvedt, T., Gustafsson, Snko, J., Linet, 0., lIertting, 198, 201, 229, 240, 268 B. 165,184 G.8,15 -- Giarman, N. J. 213, 229 Strang, L. B., see Mason, G. A. - see lIertting, G. 735, 736, -- Lishajko, F. 189, 229, 917,920,929 737,758,834,838 236,268,498,536,616 Straub, R. W. 686, 691, 724 - see Pichler, II. 8, 14 - Wennmalm, A. 200, 229 - see Greengard, P. 691, 718 Sulser, F., Bickel, M. II., Bro• - see Euler, U. S. von 609,639 - see Ritchie, J. M. 686, 691, die, B. B. 499, 500, 536 - see lIamberger, B. 240, 264 723 - Watts, J., Brodie, B. B. - see lIedqvist, P. 240, 264, Straus, R., Wurm, M. 905, 932 499,500,536 568,610 Street, B. W., see Aldridge, W. - see Gillette, J. R.499,500,526 - see Lagercrantz, II. 248, N. 411, 412, 441 Sunden, T., see Euler, U. S. v. 249,250,266 Street, D. M., Roberts, D. J. 270,280 - see Oliverio, A. 194, 227 128,132,184 Sunderman, C. R., Sunderman, - see Roth, R. II. 50, 53, 71, Strieder, N., Ziegler, E., Wink• F. W., Ballinger, W. F. 912, 77, 196,228,235,267,902, ler, II., Smith, A. D. 908, 932 904,916,930 932 Sunderman, F. W., see Sunder• Stock, K., Westermann, E. O. - see Winkler, II. 26, 44, 592, man, C. R. 912, 932 170,184,381,386,459 593,617,906,907,908,933 Sundler, F., see Larson, B. 133, - see Bieck, P. 170,172 Strobach, II., see Greeff, K. 179 - see lIoltz, P. 337, 359, 864, 912,920,926 Suomalainen, P., Uuspaa, J. 889 Strom, G. 488, 536 122,184 Stock, R. 850, 897 - see Euler, U. S. v. 22, 41, Sussman, K. E., Vaughan, G. Stocken, L. A., see Prusoff, W. 902, 911, 925 D. 420, 460 II. 249, 267 Stromberg 872 Suter, E. R. 416, 460 Stockle, D., see Fleckenstein, A. Stromberg, J.·O., see Elofsson, - Staubli, W. 416, 460 336,337,351,358,737, 757 R. 99, 100, 106 Sutherland, E. W., Cori, C. F. Stohr, P. 783, 784, 811 Stromblad, B. C. R. 166, 184, 10,15 Stoepel, K., see Kroneberg, G. 241,268, 271, 282, 816, 842, - 0ye, 1., Butcher, R. W. 363, 619,631,655 914,932 460 Stolz, F. 1l0, 184 - Nickerson, M.197, 198, 201, - RaIl, T. W. 10,15,367, 369, Stone, C., see Goodall, McC. 206,229,341,361,816,842, 460 901,926 914,932 -- Menon, T. 401, 460 Stone, C. A., Porter, C. C. 618, Struck, E., Ashmore, J., Wie• - Robison, G. A. 367, 371, 639,652,659 land, O. 373, 374, 459 395,396,460 -- Stavorski, J. M., Lud• Stuart, D. G., Kawamura, Y., -- Butcher, R. W. 395, 396, den, C. T., Totaro,J.A. 827, lIemingway, A. 494, 536 460 842 Stuckey, W. J., see Beltran, G. - see Butcher, R. W. 314, 331, - Ross, C. A., Wenger, II. C., 924 381,382,386,444 Ludden, C. T., Blessing, J. Studnitz, W. v. 237, 268, 852, - see Davoren, P. R. 433, 445 A., Totaro, J. A., Porter, C. 857,858,874,898,900,912, - see De Robertis, E. 427, 446 C.468, 536, 646, 659 913,917,921,932 - see lIandler, J. S. 433, 449 - Stavorski, J. M., Ludden, C. - lIanson, A. 921, 932 - see Jefferson, L. S. 368, 370, T., Wenger, II. C., Ross, C. - Kaser, II., Sjoerdsma, A. 450 A., Totaro, J. A., Porter, C. 920,921,932 - see Klainer, L. M. 401, 427, C. 647, 659, 823, 842 - Ljungberg, O. 914, 932 451 ---- Torchiana, M. L. - see lIanson, A. 875, 889, - see Makman, M. II. 367, 344,361 921,927 368,453 - see Porter, C. C. 625, 626, - see Ljungberg, O. 901, 929 - see Murad, F. 367, 371, 392, 637, 638, 657, 823, 826, 841 - see Sjoerdsma, A. 626, 658 396,399,455 - see Torchiana, M. L. 623, Stump, J. M., see Grelak, R. P. - see 0ye, 1. 10, 14, 433, 455 624,628,635,651,659 870,888 - see RaIl, T. W. 370, 456 Stone, D. B., see Brown, J. D. Sturkie, P. D., Lin, Y.-C. 117, - see Robison, G. A. 10, 15, 385,444 184 319,334,363,367,368,392, Stone, E. A., see Roth, R. II. - see Lin, Y.-C. 143, 179 393,395,396,405,406,407, 193,228,498,534 Sturm, A. 913, 932 441,457,462 Stoney, S. D., Machne, X. 664, Su, C., Bevan, J. A. 356, 361 - see Wosilait, W. D. 370, 462 665,668,669,724 - see Bevan, J. A. 567, 568, Sutherland, E. W., ir., see Stormorken, II. 581, 616 569,570,606,767,803 Bueding, E. 405, 406, 444 Story, D. F., see Cairncross, K. - see Chang, C. C. 159, 173 Svanborg, A., see Anden, N. E. D. 783, 805 Sugarman, S. R., Margolius, II. 865,866,872,874,875,881 Stott, A. W., Robinson, R. 620, S., Gaffney, T. E., Moham• Svedmyr, N., see Lundholm, L. 659 med, S. 646, 648, 651, 659 453 Author Index 1001

Svenaeus, K., see Falck, B., Takagi, H., Satoh, M., Yamat• Taylor, A. N., Wilson, R. W. 126,161,176 su, K., Kimura, K., Na• 428,460 Svensson, L., see Henning, M. kama, M. 498, 536 Taylor, G. S., see Daniel, E. E. 646,651,654 Takagi, K., Takayanagi, 1. 324, 319,331,406,407,440,445 Svensson, T. H., Waldeck, B. 325,334 Taylor, J., see Haydon, D. A. 503,536 Takahashi, K., see Nakajima, 593,610 Swamy, V. C., Tye, A., La S.686,722 Taylor, K. M., Laverty, R. 872, Pidus, J. B., Patil, P. N. Takahashi, R., see Aprison, M. 874,897 649,659 H. 144, 147,171 - Snyder, S. H. 865, 897 Swanbeck, G., see Euler, U. S., Takamine, J. 110, 184 - see Laverty, R. 112,179,859 von 214, 222 Takayanagi, 1., see Takagi, K. - see Snyder, S. H. 854, 865, Swedin, G., see Sjostrand, N.- 324,325,334 897 0.163,183 Takayasu, H., see Yokoyama, Taylor, K. W., see Edwards, J. Sweeney, D. C. 81, 82, 83, 87, M. 25, 45, 601, 617, 909, 911, C. 422, 446 92,95,96,97,108 933 Taylor, P., see Sjoqvist, F. 56, Sweet, R. D., see McDowell, F. Takesada, M., see Sano, 1. 118, 77,821,842 H. 861, 891 155,182 Taylor, P. M. 485, 491, 536 Swern, D., see Kirby, K. C., jr. Takeshige, C., Pappano, A. J., Taylor, P. W., see Michaelson, 426,451 de Groat, W. C., Volle, R. L. 1. A. 58,76 Swift, T., see McDowell, F. H. 704, 724 Tegerdine, P., see Kelly, M. 861,891 - Volle, R. L. 695, 705, 706, 132,178 Swislocki, N. I. 381, 390, 460 724 Tenenhouse, A., see Rasmus• Symchowicz, S., see Barnett, A. Takeuchi, A., Takeuchi, N. 675, sen, H. 372, 396, 421, 423, 212,220,339,357 694, 724 424,456,589,614 - see Korduba, C. A. 880, 890 Takeuchi, N., see Takeuchi, A. Tentori, L., see Levi-Montal• - see Wong, K. K. 420, 421, 675,694,724 cini, R. 819, 840 462 Takeuchi, T., see Ayukawa, S. Tepperman, H. M., see Allan, Symington, T., see Kennedy, J. 191,219 W.422,441 S. 902, 906,928 Talesnik, J., see Hoffmann, F. Terrell, E. B., see Regen, D. M. Szabo, A. J., see Cameron, D. 764,808 374,457 C. 918, 925 Tamarin, D. L., see Quilliam, J. Terry, L. L., see Sjoerdsma, A. Szato, S.,seePfeiffer,A.K. 61, 76 P. 814, 841 902,904,931 Szeinberg, A., see Braham, J. Tamarkin, N. R., Goodwin, F. Teufimayr, R., see Bruck, H. 850,851,884 K., Axelrod, J. 860, 897 850,884 Szelenyi, Z. 417, 460 Tamer, A., McKey, R., Arias, Tew, J. M., see Westlake, R. J. - see Donhoffer, Sz. 417, 446 D., Worley, L., Fogel, B. J. 855,899 Szentivanyi, M., see Kunos, G. 848,897 Texter, E. C., see Merrill, S. 299,333 Tanaka, T., see Fuijwara, M. 915,929 Szporny, L., see GOrog, P. 165, 129,166,176 Thaemert, J. C. 52, 71, 77 176 Tangney, A., see Dockry, M. Theiss, E., Scharer, K. 863, 897 Szreniawski, Z., Gumulka, W. 798,805 Theobald, W., see Domenjoz, 710,724 Taniguchi, K., see Sano, 1. 118, R. 500, 524 - see Gumulka, W. 701, 718 155,182 Therman, P.O., Forbes, A., Szurszewski, J. H., see Crow- Tannenbaum, M., Spiro, D., Galambos, R. 663, 724 croft,P.J. 668, 674, 688 716 Lattimer, J. K. 909, 932 Thesleff, S., see Axelsson, J. -- Holman, M. E. 677, 724 Taquini, A. C., jr., see De 834,836 - see Holman, M. E. 719 Schaepdryver, A. F. 132, - see Lundberg, A. 700, 722 Szymonowicz, L. 114,184 161, 166, 182 Thieme, G., see Anden, N. E. Tatum, E. L., see Crout, J. R. 865,866,872,874,875,881 Tabachnick, 1. 1. A., see Wong, 625, 630, 631, 632, 633, 641, - see Falck, B. 5, 13, 17,23, K. K. 420, 421, 462 653 41,815,837 Taber, R. 1., see Barnett, A. Tau9, L. 97, 98, 108, 661, 724, - see Hillarp, N. A. 541, 550, 212,220,486,504,520 783,791,812 610 Tada, K., see Arakawa, T. 852, - see Gerschenfeld, H. M. 98, Thoa, N. B., Eccleston, D., 881 106 AxeITod,J.356,361,622,659 Taeschler, M., see Salzmann, Taugner, G., Hasselbach, W. Thoenen,H. 572,616, 618,620, R. 313, 334, 353, 361 205,229,242,243,244,245, 659,828,856 Tagliamonte, A., Tagliamonte, 246,250,253,257,258,268, - Haefely, W., Gey, K. F., P., Gessa, G. L., Brodie, B. 539,616 Hiirlimann, A. 160, 167, B. 866, 897 Taxi, J. 52, 54, 56, 58, 60, 67, 184,504,536,620,621,625, Tagliamonte, P., see Taglia• 71, 77, 570, 616, 689, 724, 626,627,629,632,633,643, monte, A. 866, 897 786,812 650,659,823,842,875,897 Tainter, M. L., Chang, D. K. - Droz, B. 52, 53, 56, 77 -- Hausler, G., Hiirlimann, 336,361 - Gautron, J., L'Hermite, P. A_ 620, 628, 633, 643, 646, - see Burn, J. H. 336, 357 787,812 648,650,659 1002 Author Index

Thoenen, H., Haefely, W., Stae• Thron, C. D., Waud, D. R. 317, Tomchick, R., see Axelrod, J. helin, H. 712, 724 334 6, 11, 197, 198, 219, 239, - Hiirlimann, A., Gey, K. F., Thurm, R. H., Heidenberg, W. 262,270,272,279,504,519, Haefely, W. 628, 633, 659 J., Herron, G. R., Lau, S. 816,836,858,881 -- Haefely, W. 209, 211, H. 914, 933 - see Weil-Malherbe, H. 850, 212,229,240,268,351,356, Thurman, R. G., see William• 899 361,588,590,616,649,659, son, J. R. 373, 374, 462 Tomita, T., see Biilbring, E. 814,826,827,842 Tiedge, F., Scheiffarth, F., 298,331,795,804 - Mueller, R. A., Axelrod, J. Schmid, E. 923, 933 Tomkins, G. M., Gelehrter, T. 194, 229, 235, 268, 600, 616 Tiegs, O. W., see Corkill, A. B. D., Granner, D., Martin, D., - Tranzer, J. P. 47, 64, 77, 800,805 jr., Samuels, H. H., Thomp• 356,361,620,622,659,737, Tiemeier, O. W., see Boehlke, son, E. B. 375, 460 760,775,812,814,824,826, K. VV. 114, 136, 172 - see Granner, D. 369, 375, 827,828,829,830,831,842 Tigyi, A., see Benedeczky, 1. 433,448 -- Haeusler, G. 827, 829, 596,606 Tomlinson, N., see Nakano, T. 834,842 Tilden, J. H., see Shipley, R. E. 114,136,181 -- Hiirlimann, A., Haefely, 111,183 Torchiana, M. L., Porter, C. C., W.767,778,779,812 Timberlake, W. H., see Res• Stone,C.A.623,624,635,659 - see Axelrod, J. 195,219 nick, R. H. 880, 894 - Porter, C. C., Stone, C. A., - see Haefely, W., 199, 223, Timms, A. R., see Bueding, E. Hanson, H. M. 628, 651, 659 240,264,568,610,623,627, 405,406,444 - Wenger, H. C., Stavorski, J. 633,637,643,644,646,647, Timo-Iaria, C., see Hernandez• Ludden, C. T. Stone, C. A. 648,650,651,654,686,693, Pe6n, R. 489, 528 635,659 695,697,701,704,708,709, Tipton, K. F. 7, 15 - see Angelakos, E. T. 125, 710, 719, 753, 758, 833, 838 Tislow, R., see Wilson, S. P. 159,171, 188, 201, 219 - see Haeusler, G. 588, 610, 500,537 - see Porter, C. C. 625, 626, 666,693,704,706,712,719, Tissari, A. H., SchOnh6fer, P. 637,638,657 737,745,758,775,776,777, S., Bogdanski, D. G., Bro• - see Stone, C. A. 344, 361 807,815,827,828,831,833, die, B. B. 213, 229 Torp, A., see Bertler, A. 125, 838 Tissot, R. 877, 897 128, 131, 160, 161, 165, 166, - see Mueller, R. A. 194, 195. - Pletscher, A., Bartholini, 167,170,172 226,813,814,822,826,830. G., Constantinidis, J. 897 - see Falck, B. 5, 13, 17, 23, 834,840,904,929 - see Constantinidis, J. 872, 41, 125, 127,176, 188, 190, - see Saner, A. 829, 841 875,885 197, ]99,222,246,257,264, - see Snipes, R. L. 842 - see De AjuriaguelTa, J. 877 815,837 - see Tranzer, J. P. 46, 48, - see Ledebur, 1. X. 497, 530 Torquati, T. 852, 898 53, 56, 58, 60, 64, 67, 78, - see Monnier, M. 496, 532 Torrance, R. W., see Cabrera, 566,604,616,666,724,778, - see Pletscher, A. 873, 876, R. 704, 716, 774, 805 812,814,815,823,824,826, 893 de la Torre, J. C., see Constan• 828,831,832,843,920,933 Titus, D. C., see Porter, C. C. tinidis, J. 872, 875, 885 Thomas, H. V., see Haverback, 620,635,657,862,894 Torres, A., see Bischoff, F. 855, B. J. 851, 889 Titus, E., see Hajdu, S. 592,610 883 Thomas, R. C., see Kerkut, G. - see Ignarro, L. J. 298, 323, Torres, H. N., Marechal, L. R., A. 686, 720 327,332 Bernard, E., Belocopitow, Thompson, E. B., see Tomkins, - see Michaelson, 1. A. 58, 76 E. 404, 460 G. M. 375, 460 - see Sj6qvist, F. 56, 77, 821, - see Appleman, M. M. 401, Thompson, J. H., Campbell, L. 842 404,441 B. 822, 842 Titus, E. 0., Spiegel, H. E. 212, - see Belocopitow, E. 403, 442 Thompson, J. W. 763, 764, 229 Tosaka, T., Chichibu, S., Libet, 812 - see Dengler, H. J. 203, 208, B. 674, 678, 707, 724 - see Gardiner, J. E. 763, 765, 209,213,221 - see Libet, B. 665, 677, 678, 767,806 Tizard, J. P. M., see Scopes, J. 680,688,721 - see KosterIitz, H. W. 663, W.485,535 Totaro, J. A., see Porter, C. C. 690, 721 Tobias, J. A. Y. 862, 898 497,498,533,619,625,626, - see Paton, W. D. M. 788, Toda, N., Matsuda, Y., Shi• 636,637,638,639,644,657, 811 mamoto, K. 494, 495, 536 823, 826, 841, 86~, 894 Thomson, J. F., Habeck, D. A., Todd, W. R., see West, E. S. - see Stone, C. A. 468, 536, Nance, S. L., Beetham, K. 363,461 646, 647, 659, 823, 827, 842 L.460 Toker, C. 923, 933 Toth, J., see Lajtha, A. 465,530 - Smith, D. E., Nance, S. L., Tokuyama, T., see Creveling, Touabi, M., Jeanrenaud, B. Habeck, D. A. 411, 412, 460 C. R. 498, 523 383,390,460 Thorgeirsson, S. S., see Chal• Toman, J. E. P., see Everett, Tournade, A., Chabrol, M., mers, J. P. 877 G. M. 498, 524 Wagner, P.-E. 34, 44 Thorn, G. W., see Goldfien, A. Tomasi, V., see Marinetti, G. V. Tousignant, P., see Le Blanc, 911,926 368,377,382,453 J.132,179 Author Index 1003

Tower, S. S., see Bronk, D. W. Trendelenburg, U., Maxwell, Triner, L., Overweg, N. I. A., 663,682,690,716 R. A., Pluchino, S. 307, 327, Nahas, G. G. 405, 406, 460 Towne, J. C., see Fleming, R. 334,339,340,342,350,361, - see Kypson, J. 382, 383, 452 M.149,176 737,738,744,746,761 Trinker, F., see Cairncross, K. Tozzi, S., see Levy, B. 314, 316, - Muskus, A., Fleming, W. D. 783, 805 333 W., Gomez Alonso de la Trinker, F. R. 647, 648, 660 Traczyk,W.Z.470,471,512,536 Sierra, B. 337, 343, 344, Trombitas, S., see Barbeau, A. Tramezzani, J. H., Chiocchio, 345,351,362,648,659,737, 855,882 S., Wassermann, C. F. 17, 747, 761, 832, 833, 843 Trotter,J., see Nishida, S. 52,76 44, 48, 49, 50, 52, 68, 77 - de la Sierra, B. G. A., Mus• Truitt, E. B., jr., see Kier, L. B. Tramezzani, J. H., see Can· kus, A. 301, 334 854,890 nata, M. A. 48, 49, 50, 73 - Weiner, N. 733, 739, 761, - see Walsh, M. J. 353, 362 - seeChiocchio,S.R.23,40,68, 813, 817, 832, 833, 834, 843 Tsai, T. H. 742, 761 169, 174, 188,221,922, 925 - see Brimijoin, S. 355, 357, - Denham, S., McGrath, W. - see Houssay, B. 20, 42, 142, 730,735,736,756 R. 834, 843 178 - see Burn, J. H. 271, 280, - Fleming, W. W. 355, 362 - see Wassermann, G. F. 20, 813,816,836 - Langer, S. Z., Trendelen- 44, 116, 142, 184 - see Crout, J. R. 217, 221, burg, U. 343, 344, 345, 351, - see Wurtman, R. J. 116, 338,358,468,502,523 362 124,185 - see Drask6czy, P. R. 349, - Wendt, R. L., McGrath, W. Trano, Y., see Sourkes, T. 15 350,358,734,737,739,746, R. 341, 362 Tranzer, J. P. 68 747,748,749,750,753,754, - see Smith, C. B. 157, 183, - Snipes, R. L. 56, 77 757 734,760,815,817,818,833, - Thoenen, H. 47, 48, 53, 56, - see Fleming, W. W. 340, 842 58,60,64, 77, 78,566,604, 358,739,757,833,838 Tseng, L. F., Walaszek, E. J. 616, 666, 724, 778, 812, 814, - see Graefe, K. H. 9, 13, 728, 854,898 815, 823, 824, 826, 828, 831, 738,739,740,741,742,746, Tsudzimura, H., see Feldberg, 832,843,920,933 758 W.478, 525, 584, 609 -- Snipes, R. L., Richards, - see Hennemann, H.-M. 816, Tiirker, R. K., see Kayaalp, S. J. G. 46, 48, 56, 64, 67, 78, 838 0.584,612 823, 824, 828, 843 - see Langer, S. Z. 307, 308, Tiirler, K., see Kaser, H. 919, - see Richards, J. G. 67, 76 309,313,327,333,340,359, 928 - see Snipes, R. L. 842 726,727,730,733,734,738, Turner, J. W., see Guldberg, H. - see Thoenen, H. 356, 361, 744,745,746,747,754,759, C. 859, 888 620,622,659,737,760,767, 817,818,833,839 Turner, P., see Coupar, I. M. 775,778,779,812,814,824, - see Lee, F. L. 338, 359, 584, 327,328,331 826,827,828,829,830,831, 612,626,655 - see Hedges, A. 323, 325, 332 834,842 - see Pluchino, S. 340, 360, Turtle, J. R., Kipnis, D. M. 386, Treciokas, L., see Markham, C. 726, 734, 735, 760, 834, 841 419, 420,421,433,434, 460 H. 863, 892 - seeSmith,C.B.157,183,734, - Littleton, G. K., Kipnis, D. Treherne, J. E. 101, 109 760, 815,817,818,833, 842 M.460 Treister, G., see Barany, E. H. - see Tsai, T. H. 343, 344, Twarog, B. 99 817,836 345,351,362 Twente, J. A., see Twente, J. Trendelenburg, P. 1,5,9, 10,15 - see Van Orden, L. S. 46, 52, W.119,184 Trendelenburg, U. 9, 203, 211, 56, 78, 348, 362, 729, 734, Twente, J. W., Cline, W. H., 217,229,241,268,297,302, 761, 814, 817, 833, 843 Twente, J. A. 119, 184 307,337,339,340,354,361, - see Wagner, K. 737, 761 Tyee, G. M. 875, 898 468,537,569,632,634,659, - see Weiner, N. 209, 230, - Muenter, M. D., Owen, C. 661,684,687,688,694,698, 814,817,843 A., jr. 871, 874, 880, 898 700,702,703,705,707,708, Tl'enner, N. R., see Buhs, R. P. - see Sheps, S. G. 911, 912, 931 709,724,726,727,728,730, 620,652 - see Silverman, L. 918, 931 731,733,737,738,739,742, - see Prescott, L. F. 620, 658 Tye, A., Baldesberger, R., Lapi• 743,746,747,752,753,760, Trifar6, J. 587, 593, 594, 616 dus, J. B., Patil, P. N. 346, 761,783,812,813,817818, - Dworkind, J. 539, 616 351,362 832,833,843,914,933 - Poisner, A. M. 596, 616 - Patil, P. N., Lapidus, J. B. - Crout, J. R. 338, 361 -- Douglas, W. W. 555, 346,351,362 - Drask6czy, P. R. 740, 761 558,560,616 - see Lapidus, J. B. 302, 333 -- Pluchino, S. 348, 361, 729, Trifar6, J. M., see Douglas, W. - see Patil, P. N. 315, 334, 730,735,761,817,833,843 W. 592, 608 344,346,347,352,360,623, - Gomez Alonso de la Sierra, - see Malamed, S. 559, 596, 657 B., Muskus, A. 337, 341, 361 597,613 - see Seidehamel, R. J. 746, - Hahn, D., Graefe, K. H., - see Poisner, A. M. 248, 249, 747,760 Pluchino, S. 342, 361, 751, 256, 257, 259, 267, 539, 551, - see Swamy, V. C. 649, 659 752,754,761 553, 558, 559, 560, 595, 596, Tyler, M. J., see Cooper, C. J. - Jones, A. 687, 705, 709, 724 614 142,174 1004 Author Index

Udenfriend, S. 18,44, 187, 196, Udwadia, B. P., see Gulati, O. Valk, A. De T., jr., Price, H. L. 229,232,234,235,237,268, D. 299, 314, 315, 332 112,184 639, 660, 845, 848, 850, 898 Ulbricht, W. 713, 724 do Valle,J.R,Porto,A.142,184 - Clark, C. T., Axelrod, J., Ullberg, S., see Elfvin, L.-G. 31, Valzelli, L., Garattini, S. 118, Brodie, B. B. 189, 229 41,52,68,74 149,184 - Cooper, J. R, Clark, C. T., - see Rosell, S. 871, 894 - see Costa, E. 500, 523 Baer, J. E. 186, 229, 233, Ulstrom, R A., see Mirkin, B. - see Garattini, S. 500, 525 268 L. 131,180 Van Bruggen, J. T., see West, - Creveling, C. R 495, 537 Umezawa, H., see Ayukawa, S. E. S. 363, 461 - Lovenberg, W., Sjoerdsma, 191,219 Van Buren, J. M., see Weil• A. 85, 109 Underwood, M. C., see Moore, Malherbe, H. 855, 899 - Wyngaarden, J. B. 4, 15, R. E. 485, 491, 532 Van Cauwenberge, H. S., see 186, 229, 234, 268, 501, 537 Unger, R. H., Ketterer, H., Lefebvre, P. J. 915, 929 - Zaltzman-Nirenberg, P. Dupre, J., Eisentraut, A. M. Van den Bergh, S. G., Modder, 192,196,229,467,468,469, 422, 460 G. P., Souverijn, J. H. M. 497,501, 537, 636, 660 - see Madison, L. L. 422, 453 415,460 -- Gordon, R, Spector, S. Ungerstedt, U. 828, 831, 843 Vandenheuvel, W. J. A., see 497,501,503,537,619,627, - Butcher, L. L., Butcher, S. Kuehl, F. A. J. 850, 891 637,639,660 G., Anden, N.-E., Fuxe, K. Vanderipe, D. R., Kahn, J. B. -- Nagatsu, T. 194, 229, 506,537,854,898 341,362 234,269,501,505,537,619, - see Anden, N.-E. 854, 881 Vandermeulen, R.t Cession• 627,640,660,814,843,850, - see Carlsson. A. 522 Fossion, A. 123, 158, 184 898,904,933 - see Fuxe, K. 466, 467, 499, - see Bruel, van den, W. 128, - see Bogdanski, D. F. 504, 500,525 159,167,173 521 - see Hamberger, B. 662,719, - see Cession-Fossion, A. 122, - see Christenson, J. G. 853, 787, 796, 807 173 885 - see Hiikfelt, T. 47, 64, 71, Van der Schoot, J. B., see - see Creveling, C. R 189, 75 Creveling, C. R 505, 523 221,505,523 - see Norberg, K.-A. 786, 787, - see Nagatsu, T. 193, 227 - see Crout, J. R. 504, 506, 811 Van der Stricht, J., see De 507,523 Ungvary, G., Leranth, C. 688, Schaepdryver, A. F. 182 - see Dairman, W. 195, 221, 724 Van der Waal 514 234, 263, 873, 886 Ungvary, G. Y., Donath, T. Van der Wende, C., Johnson, J. - see Gordon, R 194, 223, 128,184 C.857,898 234,237,264 Unna, K. R., see Murayama, S. - Spoerlein, M. T. 857, 898 - see Hess, S. M. 224, 497, 706, 722 Vandyk, K, see Sapira, J. P. 528, 636, 639, 654 - see Sanghvi, I. 705, 723 901,931 - see Ikeda, M. 187, 194, 196, Urbanska, A., see Davis, R. A. Vane, J. R HI, 184 225,265,619,655 192,221 - see Marley, E. 515, 531 - see Levitt, M. 226, 234, 237, Uretsky, N. J., Iversen, L. L. - see Stazewska-Barczak, J. 266, 501, 530, 816, 840 64, 78, 828, 829, 831, 843 914,915,932 - see Lovenberg, W. 189, 226, - see Evetts, K D. 865, 886 Vangrow, J. S., see Conradi, E. 619, 656, 814, 840, 853, 891 Uridil, J. E., see Cannon, W. B. C.647, 648, 653 - see Mitoma, C. 878, 892 1,13 Van Harken, D. R., Dixon, C. - see Nagatsu, T. 8, 14, 187, Urquilla, P. R, Stitzel, R E., W., Heimberg, M. 373, 374, 191,193,194,227,231,232, Fleming, W. W. 315, 316, 460 234, 266, 501 533, 848, 878, 335, 348, 362, 745, 761 Van Heyningen, W. E., see 893,902,930 Ursillo, R. C., Jacobson, J. 731, Gladstone, G. P. 584, 610 - see Nikodijevic, B. 192, 227 761 Van Orden, L. S., Bensch, K. - see Oates, J. A. 191, 227, Utano, L., see Cabrera, R. 764, G., Giarman, N. J. 46, 53, 618,657 805 56,58,60,78,570,571,616, - see Pisano, J. J. 189,227 Utley, J., see Blum, J. J. 85, 634,660 - see Renson, J. 864, 894 105 -- Langer, S. Z., Tren• - see Senoh, S. 823, 841, 842, Uuspaa, J., see Suomalainen, delenburg, U. 46, 52, 56, 78, 856,896 P. 122,184 348,362,729,734,761,814, - see Sjoerdsma, A. 189, 228, Uuspaa, V. J. 119, 122, 159,184 817,833,843 851, 896, 902, 904, 916, 931 Uvnas, B., see Folkow, B. 762, - Bloom, F. E., Barrnett, R - see Spector, S. 187, 190, 806 J., Giarman, N. J. 46, 48, 191,194,196,228,235,268, 53, 56, 58, 60, 78, 815, 843 501, 502, 536, 637, 639, 658, Valadares, J. R. E., see Friesen, - Burke. J. B.. Geyer. M.• 851,897 A. J. D. 394, 398, 447 Lodoen, F. V. 786, 787, 812 - see Weissbach, H. 191,230, Valdecasas, F. G., Salva, J. A., - Schaefer, J. M., Burke, J. 619,660 Cuenca, E. 354, 362 P. 52,56,60, 67,70, 78 - see Zhelyaskov, D. K 501, Valette, G., see Jacquot, C. 351, - see Pluchino, S. 734, 760 537 359 - see Rude, S. 89, 96, 108 Author Index 1005

Vanov,S.,Vogt,M.124,156,184 Verity, M. A., Bevan, J. A. Vogel, F. S., see Robertson, D. - see Hollands, B. C. S. 730, 730, 731, 761 M. 920, 930 758,787,808 -- Ostrom, R. J. 569, 616 Vogel, W. H. 868, 898 - see Sharman, D. F. 159, - see Bevan, J. A. 569, 606, - McFarland, H., Prince, L. 183,272,281 731, 756 N. 853, 854, 898 Van Woert, M. H., Bowers, M. Vernadakis, A., Woodbury, D. - Orfei,V., Century, B. 854,898 B., jr. 859, 872, 876, 879, M. 465, 537 - Snyder, R., Hare, T. A. 853, 898 Vernier, V. G., see Grelak, R. P. 854, 867, 868, 898 - Heninger, G., Rathey, V., 870,888 Vogt,M. 2,4, 15, 112, 119, 120, Bowers, M. B., jr. 862, 865, Vernikos-Danellis, J., Marks, 121,124,152,156,184,272, 866,898 B. H. 435, 461 282,463,486,505,537,538, - Prasad, K. N., Borg, D. C. Verniory, A., see Mahaux, J. E. 589,617,820,821,830,834, 857,898 912,929 843,855,898 - see Cotzias, G. C. 4, 13, 846, Vesell, E. S., see Wurtman, R. - see Banister, R. J. 19, 39, 857, 860, 864, 885 J. 232, 235, 269, 903, 933 115,171 Varagi6, V. 742, 752, 761 Vetulani, J., see Maj, J. 503, - see Bell, C. 567,568,569,606 Vargiu, L., see Gessa, G. L.183, 504,530 - see Borchard, F. 159,172 881,887 Vialli, M. 89, 109 - see Dagirmanjian, R. 495, Vargui, L., see Spano, P. F. - see Erspamer, V. 133, 175 496,523 170 Vianna Dias, M., see Brown, G. - see Holzbauer, M. 5, 14, Varma, B., see Rand, M. J. 768, L.796,797,798,799,800,804 131, 178, 244, 265, 814, 839 811 Vieth,J., see Baust, W.477, 520 - see Juorio, A. V. 117, 147, Varma, D. R. 727, 761 Villar-Palasi, C. 404, 461 178,637,638,655 - Benfey, B. G. 651, 660 - see Goldberg, N. D. 404, 448 - see Laverty, R. 159, 179, - Gillis, R. A., Benfey, B. G. - see Larner, J. 404, 452 823,826,839 338,362 - seeSchlender,K.K.401,458 - see Muscholl, E. 39, 43, 124, - McCullough, H. N. 738, 739, Vincent, N. H., see Blukoo• 156,180,498,532,550,613, 761 Allotey, J. A. 399, 443 787,810 - see Benfey, B. G. 298, 330, - see Ellis, S. 319, 331, 376, - see o'Keeffe, R. 148, 154, 353,357 446 181,855,893 Varon, S., Nomura, J., Shooter, Vincent, S. 18, 44 - see Sanan, S. 148,182 E. M. 819, 843 Vincenzi, F. F., see Appel, W. - see Sharman, D. F. 148, Vartiainen, A., see Penttila, O. C. 765, 803 159, 183, 272, 281 866,893 Viola, M., see Bagnoli, P. 109 - see Vanov, S. 124, 156,184 Vatter, A. E., see Crain, S. M. Viola-Magni, M. 599 Vohra, M. M. 589, 617 819,837 Viola-Magni, M. P., see Mal- Volle, R. L. 319, 335, 661, 676, Vaughan, G. D., see Sussman, valdi, G. 30, 43 682,687,688,697,699,705, K. E. 420, 460 Virligh, S., Korenyi Both, A. 724, 725, 783, 788, 812 Vaughan, M. 388, 460 22, 27, 30, 39, 44 - Pappano, A. J. 676, 682, - Murad, F. 381, 382, 384, Virden, C. J., see Epstein, D. 705, 725 386,460 858,886 - see De Groat, W.C. 706,707, - Steinberg, D., Lieberman, Vischer, M. B., see Azuma, T. 708,716,788,805 F., Stanley, S. 388, 461 114, 115, 140. 142, 171 - see Gebber, G. L. 685, 686, - see Mosinger, B. 381, 382, Vivaldi, G., see Levi-Montal• 697,701,706,718 383,454 cini, R. 819, 840 - see Hancock, C. 686, 697, - see Murad, F. 381, 390, 392, Viveros, H., see Cabrera, R. 703, 705, 719 393,395,404,405,455 704, 716,764,774,805 - see Jaramillo, J. 686, 695, Vaz Ferreira, see De Robertis, Viveros, O. H., Arqueros, L., 697,701,703,704,705,706, E. D. P. 562, 563, 596, 608 Connett, R. J., Kirshner, N. 708, 720 Veals, J., see Korduba, C. A. 540,542,551,553,556,557, - see Komalahiranya, A. 713, 880,890 558,559,560,617 721 Veerdonk, F. C. G. van de, see -- Kirshner, N. 34, 44, 239, - see Pappano, A. J. 696, 704, Brouwer, E. 116, 173 246,250,254 257 261,269, 723 Veilleux, R., see Selye, H. 425, 540,551,553,555,557,558, - see Takeshige, C. 695, 704, 458 559,560,562,565,587,595, 705,706,724 Veldkamp, W., see Johnson, G. 598,600,604,617 Vonderahe, A. R., see Hehman, A. 502, 528 - see Duch, D. S. 540, 557, K. N. 464, 527 Vendsalu, A.ll1, 131, 132,184, 559,608 Voorhess,M. L. 905, 918,921,933 911,933 - see Ferris, R. M. 244, 245, - Gardner, L. 1. 920, 921, 933 - see Hillarp, N. A. 904, 907, 248,255,257,258,259,264, - see Chatten, J. 917, 925 927 595,596,609 Voorhoeve, P. E. 517, 537 - see Sjoerdsma, A. 6HI, 658 - see Kirshner, N. 595, 612 Votava, J., see Weight, F. F. Verdesca, A. S., see Scian, L. F. Vizi, E. S. 795, 796, 812 683, 725 915,931 - see Paton, W. D. M. 793, Vulliemoz, Y., see Poyart, C. F. Verity, M. A. 731, 761 794,795,796,811 389,456 1006 Author Index

Vyaz'mina, N. M., see Manuk• Wale, J., see Raper, C. 316, 334 Wastila, W. B., see Maxwell, R. hin, B. N. 117, 143,180 Walker, C. A., see Friedman, A. A. 130, 169, 180, 354, 360, Vyklicky, L., see Anden, N.-E. H.119,176 736,760 518,519 Walker, G., see Jones, N. F. Watanabe, A. M., Chase, T. N., 851,890,913,916,928 Cardon, P. V. 864, 898 Wada, J. A. 470, 471, 537 Walker, R. J.I09 Waterson, J. G., Hume, W. R., - McGeer, E. G. 154, 184 - Woodruff, G. N., Glaizner, de la Lande, I. S. 780, 812 - Wrinch, J., Hill, D., B., Sedden, C. B., Kerkut, - see De la Lande, I. S. 348, McGeer, E. G., McGeer, P. G. A. 97, 98, 109 358, 732, 757, 833, 837 L. 470, 479, 514, 537 - see Kerkut, G. A. 82, 89, Watlington, C. 0.434,461 - see McGeer, P. L. 150, 180, 94,95,96,97,107 Watson, L. S., see Porter, C. C. 495,497,498,530 - see Sedden, C. B. 82, 93, 94, 862,894 Wada, Y., see Arakawa, T. 852, 108 Watson, P. J. 695, 696, 705, 881 - see Woodruff, G. N. 97, 109 708, 709, 710, 725 - see Itoh, C. 123, 178, 232, Wall, P. D. 665, 694,725 Watt, A. J. 795, 812 265, 906, 912, 928 Wallace, D. K., see Anlyan, W. - see Cowie,A.L. 795, 796,805 - see Sato, T. 905, 912, 931 G. 861, 881 - see Kosterlitz, H. W. 298, Wade, D. R., Hales, C. N. 388, Wallenberg, L., see Oro, L. 333,792,793,794,795,809 389,461 387,455 Watt, J. 850,898 Waelsch, H. 465, 474, 476, 537 Wallis, D. I., see Kosterlitz, H. Watters, G., see Kelleher, J. Wagermark, J., see Hamber• W. 663, 673, 675, 676, 678, 912,928 ger, C. A. 922, 927 680,682,690,691,695,696, Watts, J., see Sulser, F. 499, Wagner, H. H., see Kamijo, K. 697, 703, 721, 789, 809 500,536 271,281 Walsh, D. A., Perkins, J. P., Watzka, M., see Muscholl, E. Wagner, H. P., see Kaser, H. Krebs, E. G. 401, 461 23, 43, 169,180 922,928 - see Brostram, M. A. 404, 443 Waud, D. R. 288, 302, 307, 308, Wagner, J. W., de Groot, J. Walsh, M. J., Davis, V. E., 335,744,761 488,489,490,537 Yamanaka, Y. 864, 898 - see Liebman, J. 354, 359 Wagner, K., Trendelenburg, U. - Hollander, P. B., Truitt, E. - see Thron, C. D. 317, 334 737,761 B., jr. 353, 362 Waugh, J. M., see Roth, G. M. Wagner, P.-E., see Tournade, - see Davis, V. E. 864, 886 901,930 A. 34, 44 - see Yamanaka, Y. 864, 899 Weakley, B. S., see Coupland, Waisman, H. A., see Copps, S. Walsh, S. A., see Williams, R. R. E. 21, 23, 25, 27, 36, 37, G. 852, 885 H. 382, 462 39,41,909,925 Wakade, A. R., Cervoni, P., Walter, H., see Holtz, P. 188, Weaver, W. T., see Anlyan, W. Furchgott, R. F. 338, 362 224 G. 861, 881 - see Kirpekar, S. M. 213, Walter, R., see Dou~a, T. 433, Webb, J. G., see Gibb, J. W. 225,588,612,781,782,808 446 851,887 Wakim, K. G., see Manger, W. Waltman, S., Sears, M. 813, Webb, R. L., see McCarl, R. L. M.120,180 816,822,843 398,454 Walaas, 0., see Berdal, P. 922, Walton, J. N., see Hughes, R. Weber, E., Muscholl, E. 212, 923,924 C. 865,866, 869, 889 230, 622, 649, 660, Walaszek, E. J., see Burford, Waltz, J. M., see Stellar, S. 861, - see Muscholl, E. 208, 227, H. 743, 756 865,897 349,360,622,649,657 - see Tseng, L. F. 854, 898 Walzak, M. P., see Mulholland, Weber, L. J. 635, 660 Wald, F., see Gerschenfeld, H. S. G. 901, 929 Weber, W. W., Zannoni, V. G. M.466,526 Wang, C. T., see Neff, N. H. 876,898 Waldeck, B. 351, 362, 620, 621, 639,657 Webster, E. J., see Samorajski, 624,625,626,660 Ward, A. A., jr., McCullough, T. 198, 199, 211, 228 - see Almgren, O. 621, 626, W. S., Magoun, H. W. 846, Wechsler, see Coons 482 630,652 898 Weddell, J. M., see Pullar, I. A. - see Anden, N.-E. 199,209, Warner, H. A., see Cameron, D. 859,872,873,894 219 C. 918, 925 Weeth, J. B., see Shealy, C. N. - see Carlsson, A. 190, 204, Wartenberg, H., Baumgarten, 870,896 213,221,243,244,245,246, H. G. 52, 68, 72, 78 Weetman, D. F., see Burn, J. 253,259,263,337,350,352, Waser, P. G. 696, 725 H. 763, 805 357,358,498,501,505,506, Wasserman, M., see Levy, B. Wegienka, L. 0., see Karam, J. 522, 542, 558, 607, 619, 621, 310,333 H. 422, 451 622,626,629,636,644,645, Wassermann, G. F., Tramez• Wegmann, A. 160, 161, 166, 653 zani, J. H. 20, 44, 116, 142, 167,185 - see J onasson, J. 245, 266 184 - Chiba, C., Chrysohou, A., - see Persson, T. 503, 533 - see Houssay, B. 20, 42, 142, Bing, R.J.125,185,815,843 - see Svensson, T. H. 503, 536 178 - Kako, K. 198, 230 Waldmann, T. A., see Sjoerds• - see Tramezzani, H. H. 17, Wegmann, R., see Maeda, T. rna, A. 912, 931 44, 48, 49, 50, 52, 68, 77 857,891 Author Index 1007

Wei, S. H., see Schlender, K. K. Weinshilboum, R, Axelrod, J. Welsh, F., see Burn, J. H. 781, 401,458 855,899 805 Weidmann, H., see Salzmann, Weinstein, I., see Heimberg, M. Welsh, J. H. 102, 103,109,854 It. 313, 334,353, 361 373,374,375,449 - King, E. C. 81, 87, 109 Weight, F. F., Votava, J. 683, Weinstein, P., see Furchgott, - Loveland, R E. 103, 109 725 !t.F. 271,280,742, 752, 757 - Moorhead, M. 87, 89, 90, Weightman, D., see Hughes, R Weir, M. C. L., McLennan, H. 99,109 C.865,866,869,889 783, 784, 791, 812 - Williams, L. D. 87, 88, 109 Weil-Malherbe, H. 132, 185, Weisbrodt, N. W., Hug, C. C., - see Jaeger, C. P. 94, 107 464,537,854,898,905,933 jr., Bass, P. 327, 335 - see Maynard, D. M. 99, 107 - Axelrod, J., Tomchick, R Weise, V. K., see Fischer, J. E. - see Mirolli, M. 96, 108 850,899 618,653,776,806 - see Stephens 81,91 - Bone, A. D. 4, 15, 132, 185 - see Kopin, I. J. 196, 205, Wendt, R L., see Tsai, T. H. - Liddell, D. W. 120, 185 208,225,235,266,338,352, 341,362 - Posner, H. S. 244, 258, 259, 359,498,529,573,612,619, Wenger, H. C., see Stone, C. A. 269 621,626,629,633,639,640, 344,361,468,536,646,647, -- Bowles, G. R 495, 505, 641,642,646,655 659,823,842 537 - see Krauss, K. R 630, 655 - see Torchiana, M. L. 635,659 - Smith, E. R B. 903, 933 - see Musacchio, J. M. 201, Wenger, J. I., see Larner, J. - Van Buren, J. M. 855, 899 216,227,338,352,360,503, 404,452 - Whitby, L. G., Axelrod, J. 532,619,620,621,626,636, Wenke, M. 387, 461 209,213,230,504,537 645,656 - Lincova, D., CepeHk, J., - see Axelrod, J. 197, 198, - see Sedvall, G. C. 639, 658 Cernohorsky, M., Hynie, S. 219,239,262,816,836 Weiss, B. 428, 429, 461 291, 312, 335 - see Gutman, Y. 164,177 - Costa, E. 427, 429, 461 - see Cernohorsky,M.301,331 - see Whitby, L. G. 198, 230, - Crayton, J. 429, 461 Wenke, W., see Lincova, D. 239,269,276,282,816,844 - see Ebadi, M. S. 431, 446 387,453 Weinbren, M., see !teis, D. J. Weiss, H., see Hajdu, S. 592, Wennmalm, A. 193, 230, 236, 118, 119, 120, 151, 182 610 269 Weiner, N. 235, 269, 858, 899 Weiss, J., see Luppa, H. 114, - see Stjarne, L. 200, 229 - Burack, W. R, Hagen, P. 179 Wense, T., see Bayer, G. 85, 105 B. 548, 550, 560, 617 Weiss, P. 189,230 Wentink, E. 479, 537 - Drask6czy, P. R, Burack, Weiss, Z., see Goldstein, M. Werdinius, B. 860,899 W. R 241, 269, 337, 338, 189,190,223 - see Anden, N.-E. 498, 518, 362, 914, 933 Weissbach, H., Lovenberg, W., 519, 855, 859, 865, 866, 872, - Jardetzky, P. 250, 269 Udenfriend, S. 191, 230, 874,875,881 - Langer, S. Z., Trendelen- 230,619,660 - see !toos, B. E. 506, 534 burg, lJ. 814, 817, 843 - seeBogdanski,D.F.504,521 Werle, E., Sell, J. 619, 660, 852, - Perkins, M., Sidman, R L. - see Lovenberg, W. 189,226, 899 130,170,185 619,656,814,840,853,891 Werrbach, J. H., Gale, C. C., - !tabadjija, M. 194, 230 - see !tenson, J. 864, 894 Goodner, C. J., Conway, M. - !tutledge, C. O. 232, 233, Weissler, A. M., see Harris, W. J.422,461 236,269 S.491,527 Wersall, J., see Gejrot, T. 923, - Selvaratnam, I. 640, 660 Weissman, A., Koe, B. K. 498, 926 - Trendelenburg, lJ. 209, 230 502,537 - see Hamberger, B. 23, 42, - see Alousi, A. 194, 219 - see Koe, B. K. 866, 890 922,927 - see Borowitz, J. L. 251, 262 Weissman, N., see Blaschko, H. - see Hamberger, C.A. 922, 927 - see Burack, W. R 249, 261, 8,12 West, E. S., Todd, W. R, 263, 548, 550, 553, 606, Welch, A. D., see Blaschko, H. Mason, H. S., Van Bruggen, 607 5, 12, 25, 26, 31, 40, 50, 72, J. T. 363, 461 - see Lee, F. L. 338, 359, 626, 232,248,255,262,538,606 West, G. B. 121, 140, 142, 144, 655 - see Demis, D. J. 4, 13 158,185,905,933 - see !tutledge, C. O. 193, - see Hagen, P. 4, 14 - Shepherd, D. M., Hunter, R 228,498,534 Weller, J., see Klein, D. C. 429, B., MacGregor, A. 22, 44, - see Sidman, R L. 130, 170, 430,431,451 123,185 183,815,842 Weller, M., !todnight, R 428, - seeMcDougal,M.D.792,810 - see Trendelenburg, lJ. 733, 461 - see Shepherd, D. M. 18, 44, 739,761,813,817,832,833, Wells, G. P. 91, 109 122, 123, 124, 137, 143, 158, 834,843 Wells, H. 425, 426, 461 183,232,267,903,905,906, Weiner, W., see Klawans, H. - Handelman, C., Milgram, E. 931 L., jr. 890 425,461 West, G. W., see CollinS, G. G. Weinhouse, S., see Friedman, - Zackin, S. J., Goldhaber, P., S. 165,174,850,885 B. 370, 447 Munson, P. L. 425, 461 West, W.L., see Bhagat,B. 803 Weinmann, D., see Metzel, E. Wells, J. A., see Griesemer, E. Westbury, G., see Pryse-Da• 854, 856, 858, 892 C. 271, 280, 752,758 vies, J. 922, 923, 930 1008 Author Index

Wester, P.o., see Norden• Widhalm, S., see Linet, O. 144, Williams, R. H., Walsh, S. A., stam, H. 25, 43 147,179 Ensinck, J. W. 382, 462 Westermann, C. D., see Scian, Widy-Tyszkiewicz, E., see Kad• -- Hepp, D. K., Ensinck, L. F. 915, 931 zielawa, K. 496, 497, 501, J. W.382,462 Westermann, E., see Bieck, P. 504,529 - see Fine, M. B. 373, 447 170,172 Wiegand, R. E., Perry, J. E. - see Hepp, D. 389, 449 - see Holtz, P. 188,224,864, 504,537 - see Lavis, V. R. 385, 452 867,889 Wiegand, R. G., see Crain, S. - see Porte, D. 419, 422, 456 - see Nedergaard, O. A. 295, M.156,174 Williams, R. T., see Booth, A. 297,327,334 - see Everett, G. M. 496, 505, N. 877, 884 Westermann, E. 0., see Stock, 524 - see Dacre, J. C. 858, 877,886 K. 170, 184, 381, 386, 459 Wieland, 0., Siess, E. 394, 461 Williams, T., see Schnieden, H. Westfall, D. P., Fleming, W. - see Hepp, D. 382, 449 855,895 W. 340,362, 739, 761 - see Menahan, L. A. 372, Williams, T. D. 22, 39, 44 Westfall, T. C. 197, 200, 201, 374,454 Williams, T. H. 52, 70, 78, 786, 206,217,230 - see Struck, E. 373, 374, 459 812 Westlake, R. J., Tew, J. M. Wieland, T. 112,185 - Palay, S. L. 786, 812 855,899 Wielosz, M., see Maj, J. 504. Williamson, J. R. 373, 374, 392, Westman, A., see Euler, U. S. 530 393,394,395,396,399,409, v. 22, 41, 911, 925 Wien, R., see Burn, J. H. 766, 413,414,415,462 Westwood, D. A., Whaler, B. 805 - Browning, E. T., Scholz, R. C. 766, 812 Wieneke, A. A., see Woodin, A. 371,373,374,462 Whalen, R. E., see Segal, D. S. M. 592, 617 -- Thurman, R. G., 866,895 Wiesel, J., see Biedl, A. 123,172 Scholz, R. 373, 374, 462 Whaler, B. C., see Rand, M. J. Wijffels, C. C. B., see Van Ros• - Herczeg, B., Coles, H., 766,811 sum, J. M. 872, 898 Danish, R. 373, 374, 462 - see Westwood, D. A. 766, Wilcox, H. G., Dismon, G., - Kreisberg, R. A., Felts, P. 812 Heimberg, M. 372, 461 W.371,374,462 Wherry, F. E., see Kris, A. O. Wilk, E., see Gitlow, S. E. 845, - Prusinger, S., Olson, M. S., 422,452 887 Fukami, M. 409, 412, 413, Whitaker, B. D. L., see Jen• Wilk, S., see Clarke, D. D. 113, 414,415,462 kinson, D. H. 800, 801, 808 174 - Scholz, R., Browning, E. T. Whitby, L. G., Axelrod, J., Wilkenfeld, B. E., Levy, B. 406, 371,373,374,462 Weil-Malherbe, H. 198,230, 461 - Wright, P. H., Malaisse, W. 239,269,276,282,816,844 - see Levy, B. 286, 333 J., Ashmore, J. 371, 373, - Hertting, G., Axelrod, J. Wilkinson, J. H., see Maclag• 374,462 211,230 lan, N. F. 270, 281 - see Cheung, W. Y. 392, 395, - see Axelrod, J. 500, 505, 519 Wilkinson, M., see Youdim, M. 396,444 - see Hertting, G. 198, 208, B. H. 850, 899 - see Prusinger, S. B. 413, 209,212,213,224,500,528, Will, F., see Everett, G. M. 501, 415,456 813,814,816,827,833,838 524 Willier, B. H. 232, 269 - see Weil-Malherbe, H. 209, Will, L., see Boshart, C. R. 423, Willis, W. D., see Hubbard, J. 213,230,504,537 443 1. 802, 808 White, R. J., see Shinebourne, Williams, B. J., Mayer, S. E. Willman, V. L., see Cooper, T. E. A. 398, 459 393,401,461 815,837 Whitehead, T. P., see Smith, - see Mayer, S. E. 399, 454 - see Potter, L. T. 614, 813, R. A. 919, 932 Williams, C. M., Leonard, R. H. 815,816,822,830,841 Whitlock, J. P., jr., Kaufman, 921,933 Wills, J. H., see Krivoy, W. A. R., Baserga, R. 425,426,461 - see Anton, A. H. 852, 881, 703,721 Whitsitt, L. S., see Lucchesi, B. 905, 911, 913, 918, 924 Wilmanns, K., see Behringer, R. 314, 333 - see Greer, M. 855, 860, 888, K. 868,882 Whittaker, S. R. F., see Robin• 913, 918, 920, 921, 927 Wilson, A. B., see Birmingham, son, R. 913, 930 Williams, E. D. 901, 933 A. T. 356, 357, 763, 773, Whittaker, V. P. 46, 50, 54, 58, - see Collins, G. G. S. 858, 774,803 78,205,230 869,885 Wilson, J. 781, 812 - Michaelson, I. A., Kirk• Williams, F. E., see Halliwell, - see Farmer, J. B. 791, 806 land, R. J. A. 37, 44, 617 G. 500, 527 - see Rand, M. J. 776, 811 Whittington, P., see Govier, W. Williams, H. P., see Smith, R. Wilson, O. S., see Coward, R. C.298,332 A. 919, 932 F. 903, 925 Wicks, W.D.368,375,376,461 Williams, J. R., see Garcia, A. Wilson, R. W., see Taylor, A. - Kenney, F. T., Lee, K.-L. 372,374,375,447 N. 428, 460 375,461 Williams, L. D., see Welsh, J. Wilson, S. P., Tislow, R. 500, Widhalm, S., see Hertting, G. H. 87, 88, 109 537 735,736,737,758,767,775, Williams, R., see Parkes, J. D. Wilson, V. J. 515, 537 807,834,838 862,893 Windle, F. 475, 537 Author Index 1009

Wing, D. R., Robinson, D. S. Wolfe, D. E. 52, 56,78 Wright, H. N., see Gram, T. E. 390,462 - Potter, L. T. 52, 56, 78 622,625,638,648,654 - Salaman, M. R., Robinson, -- Richardson, K. C., Axel- Wright, P. F., see Moore, K. E. D. S. 390, 462 rod, J. 52, 56, 78, 200, 216, 502,532 Wing, E. S., see Barbour, H. G. 230,815,844 Wright, P. H., see Malaisse, W. 482,520 - see Potter, L. T. 614, 813, J. 421, 422, 453 van Winkle, E., see Friedhoff, 815,816,822,830,841 - see Mayhew, D. A. 419, 454 A. J. 850, 887 Wolfe, S. M., Muenzer, J., Gor• - see Williamson, J. R. 371, Winkler, H. 239, 251, 269, 539, don, R. S., jr. 423,462 373,374,462 541,592,593,594,601,617, Wolinsky, H., Glagov, S. 831, Wright, S., see Schweitzer, A. 906,907,933 844 515,516,535 - Hortnagl, H., Hortnagl, H., Wollenberger, A., Krause, E.- Wrinch, J., see Wada, J. A. Smith, A. D. 539, 540, 558, G., Heier, G. 399, 462 470,479,514,537 559,592,600,617 - see Krause, E.-G. 399, 452 Wu, C. H., see Penhos, J. C. -- Smith, A. D., Zur Ned• - see Shahab, L. 399, 458 374,375,455 den, G. 555, 617 Wolman,L.,seeRoy,S.857,894 Wu, K. S. 91, 109 - Smith, A. D. 542, 565, 593, Wolner, E. 763, 774, 812 Wiinnenberg, W., Bruck, K. 617,903,904,908,916,933 Wolstencroft, J. H., see Gonza- 418,462 - Strieder, N., Ziegler, E. 26, lez-Vegas, J. A. 10, 13 Wust, G., Kluge, A., Barkhoff, 44,592,593,617 Wong, K. K., Symchowicz, S., E. R. 913, 933 - Ziegler, E., Strieder, N. 906, Staub, M. S., Tabachnick, I. Wunderlich, M., see Nashold, 907,908,933 I. A. 420, 421, 462 B. S. 494, 533 - see Blaschko, H. 26, 40, Wong, R., see Rosenthal, I. M. Wurm, M., see Straus, R. 905, 250,251,257,262,592,593, 918,919,920,930 932 601,606,906,907,908,909, Woo, C. Y., see Somlyo, A. V. Wurtman, R. J. 32, 45 911,924 731,760 - Axelrod, J. 32, 45,120,124, - see Bradbury, S. 68, 73 Wood, D. R., see Eade, N. R. 185,232,269,428,429,431, - see Hortnagl, H. 214, 224, 233,234,263 462,903,933 600 Wood, E. F., see Richardson, -- Fischer, J. E. 431, 462 - see Plattner, H. 563, 614 J. A. 768, 811 -- Potter, L. T. 127,185 - see Schneider, F. H. 34, 44, Wood, J. G. 61, 78, 95, 96, 109, -- Sedvall,G.,Moore,R. Y. 540,555 557 558,560,562, 596,617 120,185 587,592,615 - Barrnett, R. J. 17, 44, 48, -- Tramezzani, J.116, 124, - see Smith, A. D. 5, 26, 44, 50,52,61, 78 185 248,249,250,251,268,539, - Lentz, T. L. 86, 109 -- Vesell, E. S., Ross, G. T. 551,556,562,580,592,594, Woodbury, D. M., see Verna• 232,235,269,903,933 601,616,620,634,635,856, dakis, A. 465, 537 - Chou, C., Rose, C. 874, 899 906,907,915,923,932 Woodger, B. A., see Kennedy, - Chu, E. W., Axelrod, J.127, - see Strieder, N. 908, 932 J. S.902, 906,928 164,185 Winter, M., see Faredin, I. 130, Woodin, A. M., French, J. E., - Frank, M. M., Morse, W. H., 169,176 Marchesi, V. T. 584, 617 Dews,P. B. 479, 509, 514, 537 Winters, W. D., see Mandell, A. - Wieneke, A. A. 592, 617 - Kopin, I. J., Horst, D. W., J.501,531 Woodruff, G. N., Walker, R. J. Fischer, J. E. 198, 230, 274, - see Spooner, C. E. 464, 465, 97,109 282,816,844 496,497,505,512,536 -- Kerkut, G. A. 97, 109 - Larin, F. 851, 899 Wirsen, C. 130, 185 - see Walker, R. J. 97, 98, 109 - Rose, C. M., MatthYBBe, S., - Hamberger, B. 130, 185 Woods, R. I. 44, 569 Stephenson, J., BaldeBBari• Wise, R. A. 489, 537 - see Dearnaley, D. P. 23, 41, ni, R. 874, 899 Wiseman-Distler, M. H., Sour- 70, 73, 130, 169,174 - Shein, H. M., Axelrod, J., kes, T. L., Carabin, S. 864, Woodward, J. K., Bianchi, C. Laren,F. 431, 462, 823,844 899 P., Erulkar, S. D. 665, 666, - see Axelrod, J. 428, 429, - see Sourkes, T. L. 874, 897 675,725 430,431,442,823,836 Withrington, P. G., see Davies, - see Erulkar, S. D. 665, 668, - see Glowinski, J. 465, 526, B. N. 618, 653, 711, 716 674,677,717 820,838 Witkop, B. B., see Axelrod, J. - see Jacobowitz, D. 662, 720, - see Manshardt, J. 119,180 270,279 787,808 - see Noble, E. P.466, 499, 533 - see Creveling, C. R. 498, 523 Worley, L., see Tamer, A. 848, - see Rose, C. M. 872, 894 - see Daly, J. W. 857, 886 897 - see Shein, H. M. 429, 458 - see Marki, F. 110, 115, 179 Worlledge, S. M., Castairs, K. - see Snyder, S. H. 823, 842 - see Senoh, S. 823, 841, 842, C., Dacie, J. V. 861, 899 Wurzel, M., PrUBB, T. P., Kop• 856,857,896 Wosilait, W. D., Sutherland, E. panyi, T. Maengwyn-Da• Wittenborn, J. R., see Cole, J. W. 370, 462 vies, G. D. 314, 335 0.845,885 - see RaIl, T. W. 370, 456 - see Pruss, T. P. 658 Wolf, R. L., see Mendlowitz, M. Wright, A., Jones, I. C. 20, 44, Wyatt, R. J., see Sjoerdsma, A. 845,892 116,185 866,896 64 Hdb. expo PharmakoI.. Vol. XXXIII 1010 Author Index

Wycis, H. T., Cunningham, W., Yokoyama, M., Takayasu, H. Zambrano, D. 61, 78 Kellett, G., Spiegel, E. A. 25, 45, 601, 617, 909, 911, Zannoni, V. G., see Weber, W. 869,899 933 W.876,898 Wykes, A. A., Landez, J. H. Yonemura, K., see Blackman, Zapata, P., Hess, A., Bliss, E. 192,230 J. G. 664, 668, 674, 677, 688, L., Eyzaguirre, C. 52, 70, - see Merritt, J. H. 192, 226 715 78 Wylie, D. W., Archer, S., Ar• - see Muir, T. C. 695, 706, 722 Zar, M. A., see Paton, W. D. M. nold, A. 273, 282, 750, 761 Yorke, R. E., see Denton, R. 796,811 - see Archer, S. 506, 519 M. 388, 445 Zarafonetis, C. J. D., Kalas, J. Wyngaarden, J. B., see Uden• Yoshida, H., Kanuke, K., P. 116, 142, 185 friend, S. 4, 15, 186, 229, N amba, J. 852, 899 Zatman, L. J., see Burgen, A. 234, 268, 501, 537 - see Kawasaki, A. 406, 451 S. V. 766, 804 Wyrwicka, W., Doty, R. W. - see Matsuoka, M. 118, 148, Zeldowicz, L. R., see McGeer, 489,537 180,507,531 P. L. 860, 891 - see Oka, M. 239, 246, 248, Zeller, E. A. 814, 844 Yahr, M. D. 861, 862, 864, 869, 254,255,256,259,266,267, - Barsky, J. 271, 282 872, 873, 879, 899 539,542,559,587,591,595, -- Berman, E. R., Fouts, - Duvoisin, R. C., Schear, M. 596,614 J.R.7,15 J., Barrett, R. E., Hoehn, Yoshikawa, H., see Ochi, J. 52, - see Griesemer, E. C. 271, M. M. 861, 867, 899 76 280,752,758 - see Duvoisin, R. C. 867, Yoshinaga, K., see Itoh, C. 123, - see Rabhun, J. 271, 281 886 178, 232, 265, 906, 912, 928 Zeller, P., see Pletscher, A. 814, Yaksh, T. L., see Myers, R. D. - see Sato, T. 905, 912, 931 841 481,482,484,486,487,490, Youdim, M. B. H., Bonham Zetterstrom, B. E. M., see 491,533 Carter, S., Sandler, M., Dahlstrom, A. B. 576, 607 Yamada, H., Yasunobu, K. T. Hanington, E. Wilkinson, Zhelyaskov, D. K., Levitt, M., 8,15 M. 850, 899 Udenfriend, S. 501, 537 Yamamoto, A., see Goldstein, - Sandler, M. 6, 15 Ziegler, E., see Strieder, N. 908, M. 850, 888 - see Bonham Carter, S. 850, 932 Yamanaka, Y., Walsh, M. J., 851,883 - see Winkler, H. 26, 44, 592, Davis, V. E. 864, 899 - see Collins, C. G. S. 6, 13, 593,617,906,907,908,933 - see Davis, V. E. 864, 886 858,869,885 Ziegler, W., see Donath, A. 901, - see Walsh, M. J. 864, 898 - see Sandler, M. 850, 858, 895 905,912,913,925 Yamano, T., see Ichikawa, Y. Young, D. A., see Lacy, P. E. Ziegler, W. H., Langemann, H., 248,265 420,421,452 Miiller, P. B. 905, 933 Yamatsu, K., see Takagi, H. Young, J. A., Edwards, K. D. Zieher, L. M., see De Robertis, 498,536 G. 620, 660 E. 37, 41, 61, 73 Yamori, Y., Lovenberg, W., Young, J. Z. 34, 45 - see Jaim-Etcheverry, G. Sjoerdsma, A. 854, 899 Young, R. B., Steiker, D. D., 46, 48, 56, 58, 63, 75, 126, Yanniotis, G., see De Ajuria• Bongiovanni, A. M., Koop, 161, 178, 901, 928 guerra, J. 877 G. E., Eberlein, W. R. 920, - see Pellegrino de Iraldi, A. Yard, A. C., see Mohammed, S. 921,933 52, 56, 76, 120, 181 647,656 Young, R. R., see Schwab, R. Zielinska, M., see Sourkes, T. L. Yaryura-Tobias, J. A., Dia• S.869,895 497,536,636,658 mond, B., Merlis, S. 862,899 Zileli, M. S., see Friend, G. 271, Yasunobu, K. T., see Yamada, Zackin, S. J., see Wells, H. 425, 280 H.8,15 461 Zileli, S., see Goldfien, A. 911, Yates, C. M., see Crawford, T. Zadunaisky, J. A., see Ger• 926 B. B. 112, 174 schenfeld, H. M. 466, 526 Zilkha, K. J., see Parkes, J. D. Yates, D. W., see Garland, P. Zaimis, E. 737, 761, 814, 821, 869,893 B. 415, 448 844 Ziller-Perez, H. V. 89, 109 'Yates, R. D. 25, 28, 30, 34, 45, - Berk, L., Callingham, B. Zimon, R. P., Sheps, S. G., 596,597,617 198, 230, 821, 830, 844 Hazelrig, C. G., Schirger, A., - see Chen, L-L. 52, 70, 73 - see Bowman, W. C. 479, Owen, C. A. 912, 933 - see Duncan, D. 50, 52, 68, 521, 796, 797, 798, 804 Ziabek, K., see Dolezel, D. 117, 70,74 Zaltzman-Nirenberg, P., see 174 Yawata, M., see Imura, H. 435, Spector, S. 187, 196,228 Zocche, G. P., see Clementi, F. 450 - see Udenfriend, S. 192, 194, 600,607 Yeh, B. K., McNay, J. L., 196,229,234,269,467,468, Zs.-Nagy, L 95, 96, 109 Goldberg, L. L 854, 899 469,497,501,503,505,537, - see Sakharov, D. A. 95, 108 - see Goldberg, L. L 854, 887 619,627,636,637,639,640, Zuckerkandl, E. 123, 124, 185 Yeung, D., Oliver, L T. 375, 660,814,843,850,898,904, Zur Nedden, G., see Winkler, 376,462 933 H. 555, 617 Yeung, D. P. H., see Pare, C. Zamamoto, T., see Nagatsu, T. Zweig, M., Axelrod, J. 206, 230 M. B. 856, 893 904,916,929 - see Snyder, S. H. 901, 932 Subject Index* f = Reference to a figure or formula; t = reference to a table.

Accelerans substance 1 Acetylcholine, release by, of noradrenaline Accessory male genital glands, effect of 588t denervation on noradrenaline 815 -, - -, characteristics 769-771 Acetaldehyde -, - -, effect of drugs 766-778 -, indirect effects 353 -, - -, muscarinic inhibition 767-771 -, stimulation of adrenal medulla 587t -, - -, role of calcium 588t, 781-782 Acetylcholine - release from -, binding to cholinoceptors 589 -- intestine (after catecholamines) -, content in iris 781 792-796 -, effects (on) - -- spleen 575-576 -, - adrenergic nerve cell body 695-696 -, stimulation of adrenal medulla -, - adrenergic nerve terminals 762-783 -, - phospholipid turnover 594 -, - -, antidromic AP 704, 775 -, - release of -, - -, presence of atropine 775 -, -- adenine nucleotides 549t, 551 -, - blood vessels 764 --, -- catecholamines 549t, 551 -, - cardiac adenyl cyclase 399 -, -- cholesterol 558 -, - cardiac glycogen phosphorylase 399 -, -- phospholipids 558 -, - chromaffin granules 255 -, - role of CajMg 587 t -, - conduction in C-fibres 765 Acetylcholinesterase -, - ganglia 704-705, 709-710 -, "direct colouring" thiocholine technique -, -, inotropic 764 780 -, - inotropic response to catecholamines -, distribution in organs 778-781 399 - -, effect of fixatives 781 -, - nictitating membrane 764 -, occurrence in pancreatic arterioles 584 -, -, noradrenaline-like 764 N -Acetyldopamine -, - noradrenaline storage in nerve partic- -, enterohepatic circulation 875-876 les 219 -, occurrence in insects 99,104 -, - pilomotor muscles 764 -, urinary excretion in -, - release of noradrenaline 767-771 -- - neuroblastoma 921 -, - responses to sympathetic nerve stimu- -- pheochromocytoma 913 lation 764--765 -- tumours 875 -, - skeletal muscle N -Acetylnoradrenaline, urinary excretion in -,-- -,denervated 834 neuroblastoma 921 -, - -, interaction with catecholamines N-Acetyltyramine, urinary excretion in 798,801 neuroblastoma 921 -, - spleen 764 Acid phosphatase, chromaffin cells 68 -, occurrence in -, "granule" fraction 539 -, - echinoderms 102 Actinomycin D, effecton PNMT activity 32 -, - molluscs 92 Action potential (AP) (of) -, - urochordates 103 -, adrenergic nerve terminal 704, 775 - receptors, action of adrenergic antagonists -, -, effect of 6-hydroxydopamine 666, 316 775 -, release by, of -, ganglionic -, - catecholamines from -, -, antidromic 669-671 -, -- adrenal gland 30-31,584, 587t -, -, -, effect of drugs 671 -, -- inferior mesenteric ganglion 124 -, -, -, initial segment (IS) spike 671,676 -, - (-)-a-methyldopamine 634 -, -, -, soma-dendritic (SD) spike 671, -, - a-methylnoradrenaline 634 676

* Prepared by H. Kilbinger, R. Lindmar, K. LOffelholz and E. Muscholl 64· 1012 Subject Index

Action Potential (AP) (of), ganglionic, ortho- Adenosine 3',5'-monophosphate (cyclic 3',5'• dromic 676-677 AMP; cAMP), metabolic effect on brain -, -, -, after nicotinic drugs 698 428 -, -, -, effect of veratrine 713 -, - liver (scheme) 367t, 378f -, postganglionic 690-691 Adenosine 3',5'-monophosphate phosphodi- -, -, effect of TEA 712 esterase in -, skeletal muscle after catecholamines 798 - brain 427 Additive effects - liver 367,377, 378f -, definition 754 - pineal gland 429 -, difference to potentiation 754 Adenosine triphosphatase (ATPase) Adenine nucleotides of adrenal medulla -, Na-K-stimulated, relationship to -, fate after stimulation 546-551 -, - adenyl cyclase 381-384 -, occurrence in chromaffin granules -, - amino acid transport 383 541-542 -, - glucose transport 382-384 -, release 547t--549t, 550 -,role in Adenosine diphosphate (ADP) -, - catecholamine uptake 244-248 -, effect on liver glycogen synthetase 370 -, - stimulus-secretion coupling 595- -, substrate of oxidative phosphorylation 596 41Of, 412-413 Adenosine triphosphate (ATP) Adenosine 3',5'-monophosphate (cyclic 3',5'- -, distribution in sympathetic nerves AMP; cAMP) 543f,544 -, effect on -, effect on -, - adrenal medulla 589 -, - catecholamine uptake by chromaffin -, - amylase formation in salivary glands granules 243, 253 423-425 -, - catecholamine release from chromaffin -, - brain protein kinase 428 granules 256-257 -, - calcium in liver 377 -, - liver glycogen synthetase 370 -, - calcium uptake by -, - stability of storage vesicles 253, -, -- heart 396 595-596 -, -- sarcoplasmic reticulum 397-398 -, occurrence in -, - enzymes of glycogen cycle in -, - chromaffin granules 26, 539 -, -- heart 393-394 -, - synaptic vesicles 570 -, -- skeletal muscle 401 -, rate of synthesis 550 -, -- white adipose tissue 388 -, release form -, - enzymes of glycolysis in -, - adrenal medulla 34, 547 t--549 t, 550 -, -- heart 394 -, - chromaffin granules 34, 253-256 -, -- skeletal muscle 402 -, role in stimulus-secretion coupling 595- -, - insulin secretion 420 596 -, - lipid metabolism (liver) 374-375 - uptake by chromaffin granules 243, 253 -, - lipolysis in S-Adenosylmethionine -, -- heart 394 -,occurrence 272 -, -- skeletal muscle 402 -,role in -, -- white adipose tissue 381 -, - N-methylation 231 -, - liver gluconeogenesis 371-373 -, - O-methylation 272 -, - liver glycogen 369-371 Adenyl cyclase (as, in) -, - melanophores 434 - allotopic enzyme 384 -, - phosphofructokinase in white adipose -, association with adrenoceptors 10, 363, tissue 388 392 -, - potassium fluxes in liver 376 - brain 427 -- protein synthesis in liver 375-376 - p-cells of pancreatic islets -- skeletal muscle enzymes, endogenous - -, regulation of insulin secretion 419- inhibitors 404-405 421,420f -, - smooth muscle phosphorylase 405- -, discovery 10 406 -, embedding in membrane structure 384 -, - triglycerid lipase in white adipose - foetal liver 368 tissue 385£., 387-388 - frog skin 434 -, - urea production 372, 374 - liver 367-369 - fcrmation - kidney cortex and medulla 433 - -, liver 368-369 -, mediation of effects of catecholamines in - -, relationship to -, - brown adipose tissue 408-409 - -, - p-adrenoceptor stimulation 319 -, - cardiac muscle 392-393 - -, - inotropic response 395-399 -, - liver 377,378f - -, - skeletal muscle contraction 402 -, - salivary glands 423, 427 - -, - smooth muscle activity 406-407 -, - various tissues 365 -, metabolic effect on -, - white adipose tissue 380f Subject Index 1013

Adenyl cyclase (as, in) pineal gland 429, Adrenaline (see also catecholamines), effect 431 t, 432 on (of) neuromuscular transmission 402, - red blood cells 10, 433 798-800 - salivary glands 423 -, - nictitating membrane 346 - sarcoplasmic reticulum 393, 397 -, - oxygen consumption 491 - skeletal muscle 400f,401 -, - preganglionic nerve terminals 790 - smooth muscle 405 -, - pyruvate transport in liver mitochon- - stimulation, dissociation from inotropic dria 372 response 395-396 -, - shivering - toad bladder 433-434 -, - -, intraarterial infusion 494 - tumour cells 433 -, - -, intravenous injection 494 - white adipose tissue -, - -, intraventricular injection - -, pH dependence 389 491-494 - -, relationship to -, - spinal cord reflexes - -, - glucose transport 383-384 -,- -,extensor reflexes 515 - -, - Na-K-ATPase 382-384 -, - -, flexor reflexes 515-517 Adipose tissue (see also brown-, white-), cate- -, - sympathetic ganglia cholamines in 130, 169-170t -, - -, inhibition of transmission 788 Adnamine, inhibition of OOMT 506 -, - -, membrane potential 788-792 Adrenal body, innervation of 38 -, - temperature Adrenal cortex, role in methylation of nor• -, - -, intracerebral injection 483-484 adrenaline 124 -, - -, intravenous injection (chick) Adrenalectomy, effect on urinary excretion of 484-485 catecholamines 275 -, - -, intraventricular injection 481- Adrenal glands (see also adrenal medulla or 488 chromaffin cells) -, - tension development in skeletal muscle -, catecholamines in 16-34, 36-38 402,796-798,797f -, innervation of 18-19,34-38 -, - tyrosine hydroxylase 234-235 Adrenaline (see also catecholamines) -, - vas deferens 346 -, appearance during morphogenesis 21 -, - water intake 488-491 -, autoxidation 8 -, - white adipose tissue -, distribution after administration 274- -, - -, amino acid incorporation 390 276 -, - -, amino acid transport 383 -, effect on (of) -, - -, glucose transport 383, 390 -, - adrenergic nerve cell body -, - -, lipogenesis 389-390 -, - -, depolarization 708 -, exchange with endogenous noradrenaline -, - -, generation of P-wave 682 in -, - amino acid uptake by liver 372 -, - heart 206f -, - behaviour (after) -, - isolated nerve particles 201, 219 -, - -, interaction of adrenergic anta- -, formation 186-187,231-232 gonists 508-509 -, -, concept of pathway 188 -, -- intracerebral injection 472-474 -, -, effect of corticosteroids on 31-32, -, -- intracisternal injection 469-470 232 -, -- intravenous injection 474-476 -, identification as -, -- intraventricular injection 470- -, - accelerans substance 2, 232 472,512 -, - "Sympathicus Stoff" 114 -, - blood pressure after intraventricular -, (-)-isomer injection 494, 495 -, -, potency [relative to (-)-noradrenal- -, - blood sinuses of leech 89 ine] on -, - 4500. uptake by heart 396 -,-,-,a-adrenoceptors 326,327t,328- -, - electrocortical activity 472-478 329 -, - -, interaction of adrenergic anta- -, -, -, p-adrenoceptors 321-325, 322t gonists 508 -, (+ )-isomer, noradrenaline substitution by -, - encephale isola preparation 477 625 -,- lmPP 801-802 -, metabolism 270, 274-276 -,- EPSP 789 -, -, deamination 271-272 -, - food intake 488-491 -, -, O-methylation 272-274 -, - -, interaction of adrenergic anta- -, occurrence in gonists 510 -, - amphibia 114-115, 137t, 139t- -,- heart 14lt -,- -,arthropods 101-102 -, - annelids 81 t -, - -, molluscs 98 -, - arthropods -, - infusion in man 494 -, - -, crustaceans 83 t -, - intestinal acetylcholine output -, - -, insects 84 t 792-796 -, - birds 117, 143t-147t 1014 Subject Index

Adrenaline (see also catecholamines), occur- Adrenaline (see also catecholamines), uptake rencein bony fishes 113-114, 136t, 138t (into) rates of (+)- and (-}-isomer 206f -, - carotid labyrinth 19 -, urinary excretion after adrenalectomy -, - cartilaginous fishes 113, 135t, 137t 275 -, - cephalocordates 84t Adrenal medulla -, - chromaffin cells 17-32, 36-38 -, adrenaline (in) 275 -, - -, extramedullary 123-124 -, - release by lysolecithin 592 -, - coelenterates 81 t -, - -storing cells 122 -, - echinoderms 84t -, - uptake 239 -, - flatworms 81 t -, Brownian motion of vesicles 583-584 -, - hagfishes 113, 134 t -, catecholamine(s) -, - invertebrates 79 -, - -ATP ratio 541-542 -, - lamprey 113, 134 t -, - concentration 121-123, 158t, 903, -,- mammals 905 -, - -, adrenal medulla 121-122, 158t -, - -, chemical sympathectomy 828 -, - -, blood 131 -, - -, immunosympathectomy 821 -, - -, blood vessel walls 129-130, -, - resynthesis 3,234,237,550 168t--169t -, - synthesis 231-239 -,--, brain 117-119,152t -, - turnover 903-904 -, - -, carotid body 130, 169t, 922 -, - uptake 240 -, - -, carotid body tumour 923 t -, cholinoceptors in, 584 -, - -, eye 157t -, cytoplasmic enzymes, lack of release 562 -, - -, female sex organs 127,I64t -, effect of -, - -, ganglia 120-121, 156t -, - cholinomimetic drugs 546-551, -, - -, ganglioneuroma 918t 548t--549t -, - -, gastro-intestinal tract 127-128, -, - insulin 546, 547 165t -, - ions 549t, 551 -, - -, glomus jugulare tumour 932 t -, - local anaesthetics 589 -, - -, heart 125, 159t--160t -, - morphine 546,547t -, - -, kidney 161 t -, - reserpine 547 t--548 t, 550 -, - -, liver 128, 166t -, - splanchnic nerve stimulation 546- -, - -, male sex organs 126, 162t--I64t 551, 548t--549t -, - -, neuroblastoma 918t -,enzymesin 3 -, - -, paraganglia 123-124 -, "false hormones" in 241 -, - -, peripheral nerves 120-121, 156t -, fine structure of -, - -, phaeochromocytoma 22, 904, -, - capillaries 564 905t -, - catecholamine-containing cells 52t -, - -, salivary glands 129,166t -, noradrenaline -, - -, skeletal muscle 131, 170t -, - Jdopamine-p-hydroxylase ratio 540 -, - -, skin 131 -, - -storing cells 122 -, - -, spleen 128-129, 167t -, - uptake 239 -, - -, thyroid gland 161 t -, phospholipid turnover 594 -,- -,urine 132,170t -, release of -, - molluscs 91-92 -, - adenine nucleotides 547 t--549 t, 550 -, - -, cephalopods 83t -, - catecholamines, effect of -, - -, gastropods 82t -, -- cocaine 240 -, - -, pelecypods 82t--83t -, -- colchicine 601 -, - protozoans 81 t, 85 -, -- phenoxybenzamine 240 -, - reptiles 116,142t -, -- vinblastine 601 -, - sponges 85 -, - catecholamines -, - suprarenal bodies 18 -, -- exocytosis 563 -, - sympathetic ganglia 787 -, -- mechanisms 544-546, 560--564 -, - urochordates 84t -, -- resting secretion 564-565 -, - venom of Bufo agua 114-115 -, - cholesterol 558 -, - vertebrates 110-185 -, - lysosomal enzyms 551 -, potency [relative to isoprenaline] 320- -, - phospholipids 558 321 -, stimulation of -, removal from perfusion fluid 202-203 -, -, effect on tyrosine hydroxylase 600 -, storage 253-254, 275 -,-,fate of -, -, versus noradrenaline 31-32 -, -, - adenine nucleotides 546-551 -, uptake (into) -, -, - insoluble components 508---559 -, - adrenergic nerve granules 201 -, -, - proteins 551-559 -, - blood platelets 132 -, -, - vesicle contents 594-596 -, - chromaffin granules 242, 253-254 -, -, rate of ATP resynthesis 550 -, - organs and tissues 197-198 -, -, role of CajMg 587t Subject Index 1015

Adrenal medulla, stimulus-secretion coupling Adrenergic antagonist(s), interaction with 583-598 catecholamines on spinal cord reflexes -, subcellular localization of 517 -, - adenosine phosphates 541-542 -, potencies 287 -, - catecholamines 538-542 -, types of 287 -, - chromogranin A 540 a-Adrenergic antagonists -, - dopamine-p-hydroxylase 540-542 -, discovery 9 -,- RNA 539 -, doses for satisfactory effect 299 Adrenergic agonist(s) (see also sympathomi• -, effect on metic amines) -, - "degeneration contraction" 817- -, acting on both a- and p-adrenoceptors 818 298--299 -, additional actions of 299-302, 313- -, - insulin secretion 421-423 317 -, - neuromuscular junction 800 -, changes in sensitivity to 295---297 -, - non-adrenergic receptors 316 -, definition 283 -, - noradrenaline -, equilibrium conditions during measure- -, -- uptake 209 ment of responses 317 -, -- storage 218 -, indirect actions 297-298 -, -- synthesis 195 -, partial agonists, definition 288, 289f -, interaction with -, relative affinities 289 -, - catecholamines -, relative potencies (potency ratios) -, -- behaviour 507-509 287-289 -, -- blood pressure 511 -, -, effect of neuronal uptake inhibition on -, -- food intake 510 303-304,305t -, -- temperature 509-510 -, -, revealing-subtypes of p-adrenoceptors -, - p-adrenoceptors 316-317 320--325,321t,322t p-Adrenergic antagonists -, -, role in characterisation of adrenocep- -, a.ffinity to a-adrenoceptors 314-316 tors 287 -, anti-arrhythmic effects of 314 -, removal from receptor region 302-313 -, competition with isoprenaline for satur- -, -, effect on able uptake mechanism 310--313 -, -, - potencies of competitive antago- - effect on nists 306-313 -, - adenyl cyclase stimulation by cate- -, -, - relative potencies of agonists cholamines 396 302-306 -, - a-adrenoceptors 299, 314-316 -, strong agonist, definition 289 -, - contractility of a-Adrenergic agonists -, -- cardiac preparations 314 -, concentration-response curve 300f -, -- smooth muscle 314 -, effect on -, - insulin secretion 421-423 -, - acetylcholine release from -, - non-adrenergic receptors 316 -, -- ganglia 708 -, - noradrenaline uptake 209, 299, 307 -, -- myenteric plexus 795---796 -, - rate of cardiac preparations 314 -, - ganglionic hyperpolarization 707 -, interaction with -, - melanophores 434 -, - catecholamines -, - transmission 707-708, 788 -,- -, behaviour 508,509 p-Adrenergic agonists, effect on -, - -, blood pressure 511 - ganglionic depolarization 708 -, - -, food intake 510 - ganglionic transmission 788 -, - -, temperature 509-510 - melanophores 434 -, - dibenamine 315 Adrenergic antagonist(s) -, role as partial agonist 314 -, competitive, role of saturable neuronal Adrenergic blocking agents, see adrenergic uptake process 306-313 antagonist -, definition 283 -, direct effects of 313-317 Adrenergic false transmitter(s) 618-660 -, effect on -, action of -, - lipolysis in white adipose tissue 385£, -, - guanethidine 645-646 386-387 -, - reserpine 644-646 -, - noradrenaline release 271 -, definition 619 -, - preganglionic nerve terminals 790- -, depletion of noradrenaline 636-639 791 -, effect on -, - uptake of -, - adrenergio tranElmission 650---652 -, -- catecholamines in blood platelets -, - adrenoceptors 647-648 209 -, - noradrenaline release by nerve stimu- -, -- noradrenaline, extraneuronal 209 lation 642-644 -, equilibrium conditions 317 -, - re-uptake of a.mines 648--6QQ 1016 Subject Index

Adrenergic false transmitter(s), effect on Adrenergic nerve cell body, effect of nicotinic sensitivity to noradrenaline 646-647 drugs 695-703 -, - synthesis of -, - polypeptides 709-710 -, -- dopamine 639 -, - prostaglandins 711 -, -- noradrenaline 639-M2 -, - TEA 711-712 -, formation 338, 625-629 -, - tetrodotoxin 712 -, incorporation of amines as 625-626 -, - veratrum alkaloids 713 -, interaction with noradrenaline at adreno- -, electrical properties 664t--665t, 666- ceptors 650--652 690 -, release (by) 572-573, 573f, 629-636 -, -, cell resistance 664t, 667 -, - acetylcholine 634 -, -, delayed rectification 667 -,- DMPP 634 -, -, effect of -, - indirectly acting amines 634-636 -, -, - axotomy 689-690 -, - nerve stimulation 631-634,633t -, -, - denervation 688-689 -, - spontaneous 629-631 -, -, electric time constant 667 -, resistance towards depletion by -, -, resting membrane potential 664 t, -, - guanethidine 620, 645-646 666-667 -, - reserpine 644-M5 -,-,rheobase 665t, 668 -, - tyramine 620 -, -, specific membrane capacitance 664t, -, retention (in, as) 667 -, - adrenergic nerves 621 -, electrolyte distribution 666-667 -, - microsomal fraction 620 -, fast EPSP 673-676 -, - prerequisite for release 620 -, -, characteristics 674t -, stereochemistry of 623 -, -, definition 678 -, subcellular distribution 572-573, 573f, -, -, equilibrium potential 674t, 674- 620--621 675 -,uptake 205-207,621-622 -, localization of catecholamines 67-68 Adrenergic innervation -, N-wave 678 -, accessory male genital glands 815 -, repetitive firing 668 -, brown adipose tissue 408 -, synaptic excitation -, cat nictitating membrane 348 -, -, early afterdischarge (EAD) 684 -, density of 729-733 -, -, early firing 681 -, neuro-muscular interval 569, 729-733 -, -, effect of catecholamines 789 -, rabbit ear artery 347-348 -, -, fast EPSP 673-676 -, symmetry of 383,729-733 -, -, late afterdischarge (LAD) 684 Adrenergic nerve cell axon -, -, late firing 681 -, axoplasmic flow 60, 602-603 -, -, orthodromic AP 676-677 -, B- and C-fibres 690 -, -, posttetanic phenomena 686-687 -, effect of nicotinic drugs 703 -, -, refractory period 685 -, electrical properties 690-692 -, -, slow synaptic potentials 677-684, -, electrotonic interaction between neigh- 678f,679f bouring fibres 692 -,-,-,IPSP 678--683 -, fine structure of 71 -, -, -, late late slow wave (LLN) 684 -, localization of catecholamines 67-68 -, -, -, late slow EPSP 684 Adrenergic nerve cell body -, -, -, LN-wave (late negative) 680 -, accommodation to current flow 668-669 -, -, -, P-wave 678-683 -, action potential (AP) -, -, -, slow EPSP 680 -, -, antidromic 669-673 -, threshold depolarization 665t, 668 -, -, orthodromic 665t, 676-677 Adrenergic nerve terminal(s) -, adrenoceptors 707-708 -, adrenoceptors 708 -, cholinoceptors 682 -, central nervous system (electron micro- -, -, interaction with adrenoceptors 708 scopy) 60-67, 61£-66f, 71 -,effect of -, cytoplasmic noradrenaline 570-572 -, - acetylcholine 695-696 -, degeneration after -, - adrenergic neurone blocking agents -, - 6-hydroxydopamine 666, 823 712-713 -, - surgical denervation 817 -, - amino acids 710-711 -, effect of -, - amphetamine 695 -, - acetylcholine 762-783 -, - electrical pulses 668-669 -, - adrenergic neuron blocking agents -, - hexamethonium 695, 697 712-713, 776 -, - histamine 709 -, - amino acids 711 -,- 6-hydroxydopamine 824--826,828 -, - 5-hydroxytryptamine 709 -, - 5-hydroxytryptamine 708--709 -, - local anaesthetics 589, 776 -, - local anaesthetics 712 -, - nicotinic drugs 704 -, - muscarinic drugs 704--706 -, - polypeptides 710 Subject Index 1017

Adrenergic nerve terminal(s), effect of pro- Adrenoceptor(s), concentration of ca.techol- staglandins 711 amines at -, - tetraca.ine 693, 712 -, -, methods of studying 728 -,- TEA 712 -,-,role of -, - tetrodotoxin 693, 712 -, -, - COMT 750-752 -, - veratrum alkaloids 713 -, -, - extraneuronal uptake 747-750 -, electrical properties 692-694 -,-,- MAO 752 -, electrophysiological studies 664-666 -, -, - neuronal uptake 733-740, 755, -, electron microscopy of 46-47,54-60, 756 55f, 57f, 59f, 71, 577f, 779f, 780f -, nature of, for metabolic effects 440-441 -, electrosecretory coupling 693 -, procedures for pharmacological charac- -, interaction with cholinergic terminals terisation of 287-318 778-781 -, -, theoretical concepts 287-293 -, muscarinic receptors 706-707 -, occurrence in -, nicotinic receptors 704 -, - adrenergic neurone 707-708 -, occurrence in -, - hypothalamus -, - intestinal ganglia 796 -, - -, a-adrenoceptive "hunger" system -, - sympathetic ganglia 787 490,510 -, Schwann cell processes 665 -, - -, p-adrenoceptive "satiety" system -, vesicles in 54-60, 543f, 544, 577f, 778 490,510 to 779 -, - myenteric plexus 795 Adrenergic neurone -, - skeletal muscle 801-802 -, adrenoceptors 707-708 -, - smooth muscle 792 -, cholinoceptors 694-707 -, - white adipose tissue 384-387 -, effect of noradrenaline infusion 914 a-Adrenoceptors 318-319, 325-329 -, electrophysiology 661-715 -, chemistry 9-10 -, multi-amine storage 206-207 -, definition 286 -, release of -, evidence for similarity of 325-329 -, - noradrenaline -, introduction of term 285 -, - -, effect on formation of 3 -, responses mediated on -, - -, quantal release 580 -, - autonomic ganglia 319 -, - noradrenaline, role of -, - blood vessels 325, 326 t-327 t, 328 -, -- calcium 581, 781 to 329 -, -- extragranular store 581-582 -,- CNS 319 -, -- synaptic vesicles 565-582 -,- heart 318-319,326t -, - proteins 574-578 -, - liver 319 -, - vesicular components 574-582, -, - pancreas 319 575f,579t -, - nictitating membrane 326t, 328 -, stimulus-secretion coupling 583-598 -, - seminal vesicles 326t, 329 -, subcellular dynamics 601-605,603f -, - skeletal muscle 319 -, vesicles 543f -, - smooth muscle 318-319, 325, 326t -, -, Brownian motion 602 to 327 t, 328-329 -, -, dense-cored 598 -, - spleen 326t-327t, 328 -, -, granular 543 -,- trachea 326t -, -, large 603 -, role in central actions of catecholamines -, -, noradrenergic 544 507-511 -, -, synaptic 579 p-Adrenoceptors 320-325 Adrenergic neuron blocking agents, effects on -, definition 285-286 -, acetylcholine evoked responses 774- -, responses mediated on 778 -, adrenergic nerve terminals 776-777 -, - autonomic ganglia 319 -, - blood vessels 320-321, 321 t, 322t, -, ganglia 712-713 -, noradrenaline release 774-778 324-325 -, response to nerve stimulation 774-778 -,- CNS 319 Adrenergic receptors see adrenoceptors -,- heart 318-321,321t,322t,324-325 Adrenergic synapses, morphology 347-348 -, - intact dog, vasodepression 320-321, Adrenoceptor(s) 32lt -, affinity of diastereomers of a-methylated -, - intact rat, calorigenesis 320-321, phenylethanolamines 350-351 32lt -, chemistry 9-10 -, - kidney 319 -, classification 283-335 -, - lung 320-321, 321 t -, -, experimental conditions -, - metabolism of -, -, -, intact animals 293-294 -, -- adipose tissue 319-321, 322t, -, -, -, isolated organs 293-295,294t 324-325 -, -, historical background 9, 284-286 -, -- heart 319 1018 Subject Index

p-Adrenoceptors, responses mediated on meta- J-Amino-n-valeric acid, ganglionic effects bolism of liver 319 710 -, -- skeletal muscle 319~321 Amitriptyline, effect on -, -- smooth muscle 319 - 5-HT release 500 -, - pancreas 319 - noradrenaline release form nerve particles -, - skeletal muscle 319-321, 797, 802 213 -, - smooth muscle 318--321,322-325, - noradrenaline uptake 212-213 323-324t Ammonium, effect on posttetanic hyperpo• -, - spleen 323t, 325 larization 691 -,- trachea 321, 322t, 324-325 Amphetamine -, - uterus 320--321, 322t, 324--325 -, compulsive gnawing behaviour after - -, role in central actions of catecholamines in rat 865 507-511 -, effect on -, sub-types (PI' Ps) 320--325, 321 t-- -, - adrenergic nerve terminals 704 323t, 329 -, - behaviour (after) 865 Adrenochrome, formation from adrenaline 8 -, -- intracisternal injection 511 Adreno-cortical hormone (see also glucocorti- -, -- pretreatment with a-methyltyro- coids, individual steroids), effect on sine 502--503 - extra-adrenal chromaffin cells 22 -, - ganglionic transmission 701 - extraneuronal noradrenaline uptake 749 -, - noradrenaline - liver adenyl cyclase stimulation 369 -, -- accumulation in reserpine-treated - RNA transcription 32 brain 218 - skeletal muscle phosphorylase 405 -, -- metabolism in brain 210, 218 Adrenocorticotrophic hormone (ACTH), -,- - uptake in brain 208,212 effect on -, ganglionic depolarization by 695 - PNMT activity 32 -, membrane stabilizing action of 698 - white adipose tissue -, release of AMP and catecholamines from - -, adenyl cyclase in 379 adrenal medulla by 549, 551 - -, amino acid transport in 383 -, stereotype behaviour after 865 - -, glucose transport in 383 (+ )-Amphetamine Mterhyperpolarization, see hyperpolarising -, cocaine-resistant accumulation 351 after potential -, effect on p-Alanine, ganglionic effects 710 -, - adrenal medulla, role of CajMg 587t Alcaptonuria, association with parkinson• -, - behaviour after intraventricular in- ism 848 jection 512 Aldehydereductase, occurrence in neuroblas• -, - dopamine receptors 854 toma 917 -, - mesenteric artery 773 Aldosterone, effect on PNMT activity 32 -, - noradrenaline uptake 207-208 Amantadine, treatment of parkinsonism -, - small intestine 773 869-870 -, indirect effect 351 Amine oxidases (see also benzylamine oxi- Amphibia dase, MAO, spermine oxidase) -, catecholamines in 114-116, 137t, -, occurrence in echinoderms 102 139t--141 t -,types 7-8 -, -, seasonal variations 115 Amine storage organelles, role in catechol- -, chromaffin cells 18 amine synthesis 232-233 Amylase secretion (salivary gland), regulation Amino acids of 424--426 -, depression of ganglionic transmission 710 Angiotensin -, ganglionic depolarization 710-711 -, effect on -, transport in white adipose tissue 383 -, - blood pressure after intraventricular L-Amino acid decarboxylase, see DOPA de- injection 494 carboxylase -, - dog adrenal medulla, dependence on y-Aminobutyric acid (GABA) perfusion medium 834 -, effect on noradrenaline uptake 214 -, - noradrenaline synthesis 195 -, ganglionic effects 710-711 -, - noradrenaline uptake 214 -, uptake by brain 190 -, s1i.mulation of a-Amino-3' ,4' -hydroxyacetophenone (artere• -, - adrenal medulla 587 t none), occurrence in insect cuticle 85 -, - ganglia 709-710 y-Amino-p-hydroxybutyric acid, ganglionic Annelids, catecholamines in 81 t, 89-91 effects 710 Antabuse, see disulfiram Aminochromes, formation 49--50 Antagonism 6-Aminonicotinic acid amide, depletion of -, competitive catecholamines in adrenal medulla 259 -, -, between stereoisomers in racemates 3-Alnino-I-propansulfonic acid, ganglionic 302 effects 710 -, -, concepts related to 290-291 Subject Index 1019

Antagonism competitive, "paired control" Autoradiography of adrenergic nerves, small preparation for study of 295-296 granular vesicles 56 -, irreversible, concepts related to 292- - -, uptake studies 198, 199f 293 - catecholamine-containing tissues, fine Anticholinergic drugs structure 52 t--53 t -, effect on dopamine uptake in synapto- - eNS, uptake studies 61, 466-467 somes 870 - monoamines, identification 47 -, treatment of parkinsonism 870 Axo-axonal synapses 781 Anticholinesterase, effect on Axo-dendritic synapses in - neuromuscular junction 800 - central neurones 71 - response to - sympathetic ganglion 71 -- acetylcholine 767 Axoplasm, viscosity of 602 -- sympathetic nerve stimulation Axoplasmic How, 766--767 -, effect of Antidepressant drugs, screening test 501 -, - colchicine 60 Antidiuresis, role of p-adrenoceptors 319 -, - ligature 60 Anti-insulin serum, effect on lipid meta- -, transport of bolism 373 -, - chromogranin A 574 Antimalarial drugs, antilipolytic effect 385f -, - enzymes 189, 574 Antimycin, effect on Axo-somatic synapse 795-796 - acetylcholine evoked catecholamine sec• - in guinea pig ileum 795f retion from adrenal medulla 213 - in sympathetic ganglia 71 - noradrenaline uptake into nerve particles Azide, effect on noradrenaline uptake and 213-214 release on nerve particles 213 - respiratory chain 413 Anti-parkinsonian drugs, inhibition of dop• Barium amine uptake of corpus striatum 499 -, effect on ganglionic action potential 671 Apomorphine -, release of -, adventitions movements after, in parkin- -, - ATP and catecholamines 549t, 551 . sonian patients 864 -, - chromogranins 554 t, 557 -, effect on (in) -, - dopamine-p-hydroxylase 554t-- -- dopamine receptors 854, 863 555t, 557 -, - dopamine uptake by platelets 873 -, supersensitivity to, after decentralization -, - parkinsonism 863 833 -, - sexual functions 866 B-cells in sympathetic ganglia 688 Area postrema, noradrenaline uptake 464 Behaviour Arsenate, effect on noradrenaline uptake into -, innate nerve particles 213 -, -, effects of catecholamines 469-478 Arterenone, see 2-amino-3',4'-hydroxyace• -,learnt tophenone -, -, effects of catecholamines on Arterial hypertension, treatment of 4 -, -, - classical conditioning 478 Arthropods, catecholamines in 83-84 t, -, -, - instrumental conditioning 478- 99-102 479 DL-Aspartate, ganglionic depolarization -, -, - operant conditioning 479-481 710 Behavioural arousal, after catecholamines Atrium 475,476,477 - guinea pig, a- and p-adrenoceptors 298 Benzoquinonium, effect on neuromuscular - rat, autonomic nerves 780f junction 800 Atropine, effect on Benzylamine oxidase - depolarization of adrenergic nerve termi- -, biochemistry 8 nals by acetylcholine 706 -, occurrence 7 - muscarinic ganglionic depolarization 705 -, oxidation of dopamine 8 - noradrenaline Benzyloxyamines, effect on dopamine-p- -- uptake 214 hydroxylase 193 -- release 768,775 Biophase -- storage 219 -, definition 302, 726 - posttetanic hyperpolarization 692 -,model 736 - responses to acetylcholine 764 Birds Autoinhibition (see also nicotinic drugs) -, catecholamines in 116--117,143-144t, -, definition 301 145-147t - of effects of catecholamines 301 -, chromaffin cells in 20 Autophagic vacuoles in chromaffin granules Blood, catecholamines in 131-132 20,21£ Blood-brain barrier Autoradiography of -, adult brain 464-465 - adrenergic nerves -, immature brain 464-465,474 1020 Subject Index

Blood platelets, association with catechol• Bretylium, effect on ganglia 712 amines 131-132 -, - noradrenaline Blood pressure, central control, effect of cate• -, -- concentration 190 cholamines 494-495 -, -- uptake 209 Blood vessels (see also ear, mesenteric, -, -- release 774 pulmonary artery) -, -- storage (nerve granules) 219 -, catecholamine-containing cells, fine -, - responses to structure 53t -, -- acetylcholine 774 -, catecholamines in 129-130, 168-169t -, -- nicotinic drugs 775-776 -, chromaffin cells in 17,21 -, -- sympathetic nerve stimulation -, "degeneration contraction" after trans- 775-776 plantation 817-818 -, indirect effect on atria 354 -, effect of 6-hydroxydopamine 831 -, release by sympathetic nerve stimulation Body temperature, regulation (after) 618, 776 - immunosympathectomy 821 -, uptake into organs 776 - neuronal model of 486, 487 f, 488 Brown adipose tissue - surgical denervation 813, 821 -, effect on heat production 416-418 Bony fishes, catecholamines in 113-114, -, endocrine function 417-419 136t, 138t -, growth 416 -, diurnal variation 114 -, metabolic function 407-419 Botulinum toxin, effect on -,occurrence 408 - postganglionic sympathetic transmission -, sympathetic innervation 408,416 766 -, ultrastructure 52t, 416 - responses to sympathetic nerve stimula• Bulbocapnine tion 766 -, catatonia after 854 Bradykinin -, effect on brain stem 10 -, catecholamine release from adrenal me- Butanephrine (1-(3,4-dihydroxyphenyl)-2- dulla aminobutane-1-01), effects on behaviour -, -, dependence on perfusion medium 834 469,470,511 -, -, role of calcium 587 t Butoxamine for distinction of p-adrenocep• -, ganglionic stimulation 709-710 tors 286 Brain Butyrylaldehyde, indirect effects of 353 -,I'-aminobutyric acid after 6-hydroxy• Butyrylcholine, ganglionic depolarization by dopamine 828 706 -, catecholamines (in, after) 117-119,148 Butyrylcholinesterase, distribution in central to 154t ear artery 780 -, - dopamine injection 466 -, - 6-hydroxydopamine 828 Caesium, effect on -, - immunosympathectomy 821 - late hyperpolarization 697 -, - injection - posttetanic hyperpolarization 691 -, - -, importance of injectate volume Caffeine 466-467,476 -,effect on -, - -, migration pathways 467 -, - amino acid transport 383 -, -- technique 461 -, - phosphodiesterase activity 379 -, - uptake 464-469 Calcium -, extracellular space 465 -, effect on -, 5-hydroxytryptamine after 6-hydroxy- -, - adrenal medulla 589 dopamine in 828 -, - ganglionic depolarization 705 - noradrenaline -, - myosin ATPase 398 - -, intraventricular injection -, intracellular actions 590 - -, -, disappearance after 468,469f -, metabolism in liver 377 - -, -, regional distribution 466, 468 -, movements in heart 39lf,397-398 - -, -, subcellular distribution 468 -, release of ATP and catecholamines 549, -- storage 468 551 -- turnover 467-469 -, role in -, sympathin 4 -, - adenyl cyclase stimulation in -, uptake of drugs from -, -- brain 382 -, - blood 464-465 -, -- heart 382 -, - cerebrospinal fluid 465-467 -, -- liver 368 -. - -, role of neuroglia 465-466 -, -- white adipose tissue 382 Bretylium -, - amyla.se secretion 424 -, effect on -, - catecholamine release from -, - adrenergic nerve terminal 712-713, -, -- adrenal medulla 586-592, 587 t 776-777 -, -- chromaffin granules 255-256 -, - C-fibres 776 -, - ganglionic depolarization 695 Subject Index 1021

Calcium, role in ganglionic AP 670-671 Catecholamine(s) (see also individual amines), -, - insulin secretion 421 action (effect) on (at, in, of) acetylcholine -, - liver gluconeogenesis 372 release (intestine) 792-796 -, - noradrenaline release 588t, 781-782 -, - adenyl cyclase 10 -, phosphorylase activation in skeletal mus- -, - -, brain 427 cle 403 -, - -, heart 39lf, 392-393 -, - release of dopamine-p-hydroxylase -, - -, liver 367-369 575, 575f, 587t-588t, 590 -, - -, white adipose tissue membrane -, - stimulus-secretion coupling 586- 380-384 590 -, - autonomic ganglia 783-784 Carbamyl choline (carbachol) -, - behaviour -, effect on -, - -, innate behaviour 469-478 -, - adrenal medulla 587 t -, - -, learnt behaviour 478-481 -, - food intake 488-491 -, - -, species differences 471 -, - tracheal strips 301 -, - -, stereospecificity 512-514 -, - water intake 488-491, 510 -, - p-cells of pancreatic islets 419-423, -, ganglionic depolarization by 695 420f -, ganglionic hyperpolarization by 704 -, - blood glucose concentration 436t, -, release of 437 -, - ATP and catecholamines from adrenal -, - calcium in liver 377 medulla 551,548-549t -, - cardiac glycogen phosphorylase 393 -, - lysosomal enzymes from adrenal me• to 394 dulla 551 -, - cardiac glycogen synthetase 393 Carbonic anhydrase, occurrence in glomus -, - cardiovascular system 274 cells 24 -, - central control of blood pressure Carbonyl cyanide m-chlorophenylhydrazone, 494-495 effect on noradrenaline uptake and release -, - cholinergic nerve terminals 783-796 on nerve particles 214 -, - electro cortical activity 471-478 Carbonyl cyanide p-trifluoromethoxyphenyl• -,- EPP 801 hydrazone (FCCP), effect on respiration -, - fat mobilization 11,437t of brown adipose tissue 413-414 -, - food and water intake 488-491 Carotid body 22-24 -, - ganglionic transmission 788-792 -, catecholamine-containing cells -, - intestinal motility 792-796 -, -, electron microscopy 70, 922 -, - kidney adenyl cyclases 433 -, -, fine structure 52t -, - lipid metabolism in liver 373-375 -, catecholamines in 130, 169t, 922 -, - liver gluconeogenesis 371-372 -, chemoreceptors 70 -, - liver glycogen phosphorylase 10, 369 -, chromaffin cells 22-23 to 371 -, denervation 24 -, - liver glycogen synthetase 11, 369- -, dopamine in 23 371 -, effect of anoxia 24 -, - melanophores 434 -, electron microscopic histochemistry 922 -, - mobilization of energy reserves 11, -, glomus type I and II cells 22-24, 70 435-437 -, 5-hydroxytryptamine in 23,922 -, - neuromuscular junction 796-802 -, innervation 22-24 -, - oxygen consumption 491 -, noradrenaline in 23, 922 -, - oxygen uptake of brown adipose tissue - tumours, catecholamine concentration 409-415 922,923t -, - potassium fluses in liver 376-377 Carotid labyrinth of frog, catecholamines in -, - protein kinases 11 19 -, - protein synthesis in liver 375-376 Cartilaginous fishes, catecholamines in 113, -, - salivary glands 423-427 135t, 137t -, - shivering 491-494 Castration, effect on catecholamines in -, - skeletal muscle 796-798,797f - seminal vesicles 126 -, - temperature 481-488 - vasa deferentia 126 -, - toad bladder 433-434 Cat, effects of catecholamines on -, - urea production 372 - behaviour 471-476 -, - vessels of perfused liver 367 - electrocortical activity 472,475 -, aggregation with ATP 544 - temperature 483 - /ATP ratio in chromaffin granules Catalepsy, induction by intraventricular in- - -, normal adrenal medulla 249, 257- fusion of catecholamines (dog) 470 260 Catechol, effects on EPP 802 - -, phaeochromocytoma 907-908 Catecholamine(s) (see also individual amines) -, autoxidation 318 -, accumulation studies, method 728 -, -, catalysts 8 -, action (effect) on (at, in, of) -, -, phenolase type 8 1022 Subject Index

Catecholamine(s) (see also individual amines), Catecholamine(s) (see also individual amines), blood-brain barrier 464-465, 873 release (from) -, calorigenic effect 437--438 -, - adrenal medulla -, cerebrospinal fluid-brain barrier 465- -, - -, indirectly acting sympathomimetic 467 amines 590, 587 t -, column chromatography 276 -, - -, resting secretion 565 -, conjugated forms of, in -, - adrenergic nerves, concentration at -,- mammals adrenoceptors after 752-754 -, - -, blood 131 -, - adrenergic nerve granules 186, 218- -, - -, urine 132, 276t, 277t 219 -, distribution after administration 274 -, - chromaffin cells 32-34 -, elimination studies, method 728 -, - chromaffin granules 186 -, estimation techniques 111-113 -, - -, effect of ATPfMg++ 255-257 -, -, brain 118 -, - -, possible role of chromogranin 251 -, isolation techniques 276 -, -, fundamental mechanisms 538-605 -, lipolytic effect 379, 380f -, -, mode of 544-546,545f -, -, autoinhibition of 301 -, -, -, adrenal medulla, ultrastructural -, -, events at cell membrane 381-387 evidence 560-564 -, -, inhibitory compounds 385f -, -, -, sympathetic nerves, electron -, -, intracellular events 387-390 microscopic evidence 578-580, 577 f -, -, species differences 387 -, -, subcellular mechanisms (exocytosis) -, localization in 582-605 -, - adrenergic nerve cell body 67-68 -, role in ganglionic transmission 708 -, - adrenergic nerve terminals 54-60 - role as neurotransmitters (discovery) -, - cells, cytology 68-71 1-11 -, metabolic effects (on, in) 363--441 -, staining in electron microscopy 46-54 -, - brown adipose tissue 407--419, 410f -, staining in light microscopy (see also -, - cardiac muscle 390-399 formaldehyde-fluorescent reaction) 47 -, - -, scheme 39lf -, storage -, -, adrenergic nerves 214-219 -- intact animals 435--440, 439 t -, - liver 366-379, 367t, 378t -, -, binding in the store 544-546 -, -, chromaffin granules 251-261,260 f -, - pineal gland 428--432, 430f -, - skeletal muscle 400--405,400f -, -, -, heterogeneity of store 257-258 -, - smooth muscle 405--407 -,-,-,phaeochromocytoma 907-909 -, -, -, storage complex hypothesis 252 -, - white adipose tissue 379-390, 380 f -, metabolism (in) 10, 11, 270-279, 273f, -, -, extragranule store (adrenal medulla) 540 849f -, -, neuronal stores -, -, conjugation with sulphate 270-271 (phaeochromocytoma) 914-915 -, -, deamination 270-272, 274, 278- -, -, particulate store (adrenal medulla) 279 540-542 -, -, essential hypertension 845 - structure-activity studies (brain) 511- -, -, familial dysautonomia 845 514 -,- man 845-881 -, subcellular localisation in -, - molluscs 95-97 -, - adrenal medulla 538-542 -, -, morphine addiction 845 -, - CNS 60-67 -, -, O-methylation 272-274 -, synthesis -, -, Parkinson's disease 845-881 -, -, adrenal medulla 231-239,238f -, -, phenylketonuria 845 -, -, adrenergic nerves 188--196 -, -, tyrosinosis 845 -, - and metabolism in man 845-881 -, occurrence in -, -, enzymes of -, - autonomic ganglia 784-787 -, -, -, in neuroblastoma 917 -, - chromaffin cells 16-38 -, -, -, in phaeochromocytoma 902 -, - invertebrates 79-109 -, -, -, subcellular distribution 232- -, - venoms of 233 -, -- amphibia 114-115 -, -, rate of 233-234, 550 -, -- insects 99, 104 -, -, -, effect of nop A on 237, 241 -, -- reptiles 116 -, -, -, nerve stimulation 234 -, - vertebrates 110-185 -,-,-,phaeochromocytoma 902-904 -, - thyroid tumour 901 -, -, regulation 234-236, 600 -, physiological function in fatigued muscle - turnover rate (adrenal medulla) 234,237 405 -,uptake -, radioactive amines -, -, adrenergic nerves 197-214 -, -, use in metabolic studies 274-278 -, -, -, concentration gradient 203,732f -, -, use in uptake studies 197 -, -, -, effect of drugs 207-214 Subject Index 1023

Catecholamine(s) (see also individual amines), COMT inhibitors, mechanism of action 506, uptake, adrenergic nerves, membranal 507 197-198, 337, 348-351 -, side effects 506 -, -, -, non-specific 198-199 Caudate nucleus -, -, -, specific 197-202, 205 -, dopamine turnover 469 -, -, adrenergic nerve granules 186, 200- -, types of vesicles in 64 202 C-cells in sympathetic ganglia 688 -,-, brain 198,467--469 Central nervous system (see also brain) -, -, chromaffin granules (effect of) 186, -, adrenoceptors 319 204,241-248,247f -, catecholamine containing neurones 71 -, -, - adrenergic antagonists 246 -, nerve terminals, electron microscopy -, -, - amine concentration 242-243 60-67, 6lf-66f -, -, - ATPase 205, 244-246 -, noradrenaline in synaptosomes 543 -, -, - ATPjMg++ 204,243,253 Cephalochordates, catecholamines in 84t, -, -, - 5-hydroxytryptamine 245 103 -, -, - reserpine 243-244 Cerebellum, noradrenaline turnover 468 -, -, - stereospecificity 243 Cerebrospinal fluid -, -, - sympathomimetic amines 245 -, catecholamines in 120 -, -, - temperature 242-243 -, fluid-brain barrier 465--467 -, -, extraneuronal 274, 278-279, 747- Chemodectomas 900 753 Chicken -, -, kinetic constants 203t -, effects of catecholamines on -, -, neuronal 274, 278-279, 733-747 -, - behaviour 464,473,474 -, -, saturation of 203, 744-747 -, - temperature 484, 485f, 486 -, -, vesicular 337, 352, 740-744 -, test object for central effects of catechol- -, -, -, "active uptake" hypothesis 544 amines 464,474 Chlorisondamine, supersensitivity after 833 -, uptake2 (see also extraneuronal uptake) 204,278,748 p-Chloromercuribenzoate, antilipolytic effect 385f -, urinary excretion 270 p-Chlorophenylalanine, effect on sexual acti• -, -, effect of reserpine treatment on 236 vity 866 -, -, neuroblastoma 920 4-(m-Chlorophenylcarbamoyloxy)-2-butynyl• -,-,phaeochromocytoma 912 trimethylammonium chloride (McN-A- Catechol-O-methyl transferase (COMT) 343) -, activity after denervation 816 -, effect on rabbit ear artery 768-769 -, discovery 6 -, muscarinic ganglionic depolarization 706 -, extraneuronal localization 822 m-Chlorophenylhydrazone (CCP), effect on -, methylation of noradrenaline uptake and release on nerve -,- meM-hydroxylgroup 857 particles 214 -, - para-hydroxyl group 857 Chlorpromazine -, occurrence in -,effect on -, - kidney 278 -, - dopamine receptors 854 -, - liver 279 -, - noradrenaline uptake 208 -, - neuroblastoma 917 -, -- by nerve particles 213-214 -, - phaeochromocytoma 904 -, indirect effect on cat heart 353 -, role in Cholesterol -, - catecholamine - in chromaffin granules after lysis 558 -, -- actions 274 - release from adrenal medulla 558 -, -- metabolism 272-279 Choline -, - removal of adrenergic agonists from -, ganglionic depolarization receptor region 303-304 -, -, muscarinic 706 Catechol-O-methyltransfera.se inhibitors -, -, nicotinic 695 (COMT inhibitors) 272-273 -, reversal of hemicholinium effects 765 -, effects on Choline acetyltransferase, effect of denerva- -, - actions of catecholamines 273-274 tion 765 -, - behaviour 507 Cholinergic link hypothesis 763-778 -, - catecholamines in brain 506-507 Cholinergic nerve fibres -, - extraneuronal deamination 278-279 -, effect of -, - extraneuronal uptake ofnoraruenaline -, - catecholamines on 783-796 748-750 -, - chemical sympathectomy on 824f, -, - normetanephrine in brain 507 832 -, - sensitivity to -,occurrence in adrenergic nerves 762-763 -, -- adrenaline 751-752 -, stimulation, effect on -, -- isoprenaline 750-751 -, - insulin secretion 422 -,- - noradrenaline 751-752 -, - noradrenaline release 781 1024 Subject Index

Cholinesterase, see acetylcholinesterase, buty- Chromaffin cell, noradrenaline storing, foetal rylcholinesterase life 21-22 Cholinesterase inhibitors, effect on -, -, innervation 38 - ganglionic depolarization by -, organelles (other than granules) -- acetylcholine 695 -, -, autophagic vacuoles 21£, 30, 601 -- muscarinic drugs 705 -, -, basement membrane 29, 33f - ganglionic transmission 685 -, -, cilia 29-30 Choline 2:6-xylylether (TM 10, xylocholine) -, -, desmosomes 29 -, effect on noradrenaline uptake 209 -, -, endoplasmic reticulum 27-28, 31, -, indirect effect on atria 354 599--600 -, supersensitivity after 833 -, -, Golgi elements 27, 28f, 30-31 Cholinoceptors -, -, lysosomes 19f, 27, 68, 601 -, binding of acetylcholine to 589 -, -, microtubules 27,601 -, distribution in adrenal medulla 584 -, -, mitochondria 27, 68 -, effect of local anaesthetics on 589 -, -, nucleus 30 Cholinomimetic drugs (see also muscarinic -, -, plasma membrane 28-30 drugs, nicotinic drugs) -, -, ribosomes 27,28 -, induction of tyrosine transaminase 375 -, small "emply" vesicles 596-598 -, release of -, subcellular dynamics 598--601,599f -,- chromogranin 554--555t,557 -, ultra-structure 18-39, 68-70 -, - dopamine-p-hydroxylase 554--555t Chromaffin granules (see also synaptic 557 (granular) vesicles) Chromaffin cell -, adrenaline-storing 31-32,909 -, adrenaline-storing 18, 21-22, 25, 29f, -, ATP content 26, 249 51£ -, attachment to cell membrane 590-592 -, -, basophilia 26 -, Brownian motion 583-584, 601 -, -, cytoplasmic organelles 27 -, chemical composition 249-251, 539- -, -, foetal life 21-22 540,595 -, -, innervation 38 -,- after lysis 558--559 -, definition 16 -, chromogranin A 26, 31, 540 -, degeneration 30 -, chromomembrins 601 -, distribution in -, classification 25, 26, 540-542 -, - invertebrates 17 -, components, fate of 560-561 -, - vertebrates 17 -, definition 241 -, - -, amphibia 18 -, destruction 27 -, - -, birds 20 -, diameter 68, 594 -, - -, cartilaginous fishes 113, 137t -, discharge of contents 32-34, 594-596 -, - -, cyclostomes 17,113, 134t -, discovery 5, 594 -, - -, elasmobranchii 18 -, effect of -, - -, mammals 20-22, 123--124, 576 -, - hypo-osmotic shock 559 -, - -, reptiles 20, 116 -, - hypophysectomy 600 -,enzymes -, - osmotic shock 252 -, -, acid phosphatase 27 -, - stimulation of adrenal medulla 559 -, -, cytochrome b 559 600 -, electron microscopy 68, 69f, 909-911, -, -, hydrolases 601 910f -, -, tyrosine hydroxylase 600 -, electron opacity 50, 5lf, 68, 69f -, extra-adrenal 21-25,38-39 -,enzymes -, -, carotid body 22-24 -, -, ATPase 26, 244-245 -, -, function 22, 39 -, -, cytochrome b559 26 -, -, innervation 38-39, 124 -, -, dopamine-p-hydroxylase 26,31, 559, -, -, paraganglia 123-124 595 -, -, peripheral organs 24-25 -, exocytosis 23, 33f, 34 -,-,skin 25 -, -, re-use after 601 -, -, superior cervical ganglion 39 -, formation 30-31, 244, 251, 599-600 -, -, synaptic endings 38--39 -, isolation methods 241-242, 248-249, -, innervation 16, 18-19, 34-39 539,906-907 -, - types of synaptic endings 18-19, -, labelling with aH-DOPA 31 34-39,35f -, life span 31, 601 -, membrane permeability 594 -, lipids 26 -, micropinocytosis in 596-598 -, lysis by ATPJMg 596 -, mitotic activity 30 -, lysolecithin 592-594,593t -, noradrenaline-storing 18, 21-22, 25, -, membrane 32--33 28f, 36f, 51£, 69f -, -, coating of 597f,597-598 -, -, cytoplasmic organelles 27 -, - fission 596-598 -, -, eosinophilia 26-27 -, - formation 600 Subject Index 1025

Chromaffin granules (see also synaptic (gran• Cocaine, effect on ular) vesicles), membrane fusion with cell -, - lipolysis 385 membrane 34,594--598,597f -, - muscarinic ganglionic depolarization -, - permeability 251-252,255 705 -, - proteins 559 -, - noradrenaline -, noradrenaline-storing 27, 31-32, 909 -, - -, circulating 211 -, phaeochromocytoma 906-911 -, -- outflow from perfused organs -, proteins 26 211-212 -, release of -, -- release 753 -, - ATP 253-256 -, -- storage 219 -, - catecholamines 253-257 -, - uptake of -, - -, acceleration 259 -, -- catecholamines 211-212, 218, -, - -, calcium-induced 591 274,303 -, - -, inhibitors 258-259 -, -- a-methylnoradrenaline 212 -, - chromogranin A 557 -, -- phenylethanolamine 212 -, - dopamine-p-hydroxylase 557 -, -- tyramine 339 -, - soluble components 562-563 -, indirect effect on -, small, conversion to large granules 600 -, - blood pressure 354 -, storage of -, - heart 339, 354 -, - adrenaline 253-254 -, - nictitating membrane 339, 354 -, - catecholamines 248-261 -, interaction with -, - dopamine 242, 246, 253-254, 257 -, - adrenaline on placenta 211 -, - noradrenaline 253-254 -, - tyramine 212 -, transport 601 -, -"paradox" 336 -, uptake of catecholamines 241-248 -, potentiation of directly acting amines Chromaffin reaction 16-17 339-340 -, chemistry 16 -, supersensitivity to catecholamines -, enterochromaffin cells 16 -, -, stereospecificity 746 -, mast cells 16, 25 -, supersensitivity to noradrenaline 727, -, sensitivity 17 730-734, 737-739, 751, 753, 832-833 -, use in electron microscopy 50 -, -, degree of, in various tissues 730t Chromaffin system 16-45 -, -, effect of cold storage on 738 Chromogranin A -, -, postjunctional effects 727, 731, 736, -,assay 250,557,580 738 -,axonal transport 557,602--603 -, -, relation to neuromuscular distance -, characteristics 250-251, 562 731£ -, formation 542, 599 Coelenterates, catecholamines in 81 t, 86- -, marker of "granular" fraction 540 87 -, occurrence (in) 250 Colchicine, effect on -, - chromaffin granules - adrenal medulla 601 -, - -, loss 551-556, 552t-553t - axoplasmic flow 60 -, - -, release into perfusate 556-558 - mitotic activity of chromaffin cells 30 554 t---555 t - noradrenaline transport 603 -, - "heavy" synaptic vesicles 577 Cold exposure, effect on -, - nerve granules 217 - growth of brown adipose tissue 416,418f -, - sympathetic nerves 543t, 544 - oxygen uptake 411 -, - synaptic vesicles 574 Collision technique 774 -, release form adrenal medulla Colossal cells ("chromaffin cells" ofleech) 89 -, -, resting secretion 565 erythro-Corbadrine, see a-methylnoradrenal- -, -, stimulated 557, 561£, 562 ine -, tissue binding 580 threo-Corbadrine Chromomembrin 601 -,effect on Chrothiomycin, effect on -, - adrenoceptors 648 - dopamine-p-hydroxylase 191 -, - blood pressure 624 - tyrosine hydroxylase 191 -, fluorescence with trihydroxyindole Ciba 39089 Ba, see l-isopropylamino-2-hydro• method 624 xy-3-( o-allyloxy -phenoxy)propane -, noradrenaline substitution by 625, 637 Circadian rhythms (diurnal variations) of -, release by adrenergic nerve stimulation catecholamines in 621,633t - bony fishes 114 -, retention by storage vesicles 625 - brain 119, 151 t -, upta.ke 621 - pineal gland 120 Corpus cardiacum, Brownian motion of Cocaine vesicles 584 -, depression of smooth muscle preparations Corticosterone, effect on adrenaline storage 306 32 65 Hdb. expo Pharmako\ •• Vol. XXXIII 1026 Subject Index

Cortisone, effect on extra-adrenal chromaffin Denervation (see also supersensitivity, sym• cells 32 pathectomy), effect on catecholamine con• Cyanide, effect on catecholamine uptake and centration in kidney 126 release 213 -, -- male sex organs 126 Cycloheximide, effect on salivary gland DNA -, -- salivary gland 129 synthesis 426 -, -- spleen 128-129 Cyclohexylamine, bacterial production from -, -- skeletal muscle 131 cyclamate 878 -, - heart adenyl cyclase activity 392 N-Cyclohexyl-methyl-N-ethyl-p-chloro- - supersensitivity of ethylamine (GD 131), effect on -- nictitating membrane 817, 818f, - a-adrenoceptors 304 832-834 - neuronal uptake 304 -- various organs 727,733-737,817 - non-neuronal uptake 304 II-Deoxycorticosterone, effect on PNMT acti- Cyclopentamine, affinity for noradrenaline vity 32 uptake site 207-208 Deoxyfrenolicin, antilipolytic effect 385f Cyclostomes Depression, response to L-DOPA 862 -, catecholamines in 113, 134 t Desaspidin, effect on noradrenaline uptake -, chromaffin cells in 17 and release on nerve particles 214 Cystathionine Deoxyribonucleic acid (DNA) synthesis, -, occurrence in ganglioneuroma 919 stimulation by catecholamines 425-427 -, urinary excretion in Desensitization, agonist induced 296-297 -- neuroblastoma 921 Desipramine (DMI) -- phaeochromocytoma 913 -, effect on DL-Cysteate, ganglionic depolarization 710 -, - release of Cytochrome, constituent of chromaffin -, -- catecholamines from brain 499 granule membrane 559 -, -- noradrenaline from nerve particles Cytochrome b559, distribution in chromaffin 213,218 cell 248, 600 -, - uptake of Cytochrome oxidase, in -, -- catecholamines in brain 499-501 - brown adipose tissue 411, 417 -, -- dopamine in brain 212 - glomus cells 24 -, -- noradrenaline 212-213, 218, - Helix pomatia 97 303 Cytochrome system, role in catecholamine -, -- tyramine 339 autoxidation 8 -, interaction with catecholamines -, - behaviour 500, 501 dEcAMP, see dibutyryl adenosine 3'5'• -, - eating response 501 monophosphate -, - temperature 501 DCI, see dichloroisoproterenol Dexamethasone, effect on PNMT activity Debrisoquin, adrenergic neurone block after 32, 124 712-713 Dexamphetamine, see (+ )-amphetamine Decaborane-14 DHE, see dihydroergotamine -, effect on Dibenamine -, - catecholamine levels 192 -, effect on -, - DOPA decarboxylase 192 -, - a-adrenergic agonists 300f -, interaction with pyridoxal-5'-phosphate -, - adrenoceptors 284-285 192 -, - IPSP 790-791 -, - noradrenaline uptake 208 (+ )-Decanoylcarnitine, effect on liver lipid metabolism 373-374 -, - slow synaptic potentials 682 -, - receptors Decentralization (see also supersensitivity) -, - -, acetylcholine 316 -, definition 814 -, - -, histamine 316 -, effect on -, - -,5-hydroxytryptamine 316 -, - adrenergic neurones 814 -, indirect effect on heart 353 -, - noradrenaline concentrations 190, -, interaction with p-adrenergic antagonists 815-818 315 - supersensitivity, of nictitating membrane Dibutyryl adenosine 3',5'-monophosphate 818f, 832-834 (dB cAMP) "Degeneration contraction" 735, 737, 817 -, effect on Denervation (see also supersensitivity, sym• -, - adrenal medulla 589 pathectomy) -, - amylase secretion by salivary glands -, degeneration contraction after 735,737, 423-----425 817 -, - gluconeogenesis (liver) 372 -, effect on -, - melanophores 434 -, - catecholamine concentration in -, - melatonin synthesis 429-430 -, -- adipose tissue 130 -, - metabolism Subject Index 1027

Dibutyryl adenosine 3',5'-monophosphate 3,4-Dihydroxyphenylacetic acid, occurrence (dBcAMP), effect on metabolism, brown in neuroblastoma 919 adipose tissue 409,412 -, urinary excretion -, - -, lipids (liver) 374-375 -, - after L-DOPA 874,876 -, - -, liver 367 -, - in neuroblastoma 921 -, - neuromuscular transmission 402 DL-Dihydroxyphenylalanine, treatment of -, - smooth muscle relaxation 406 parkinsonism 860 -, induction of tyrosine transaminase 375 L-Dihydroxyphenylalanine (DOPA) -, inotropic effect 395-396 -, 3f, 187f, 849f -, properties 363 -, absorption 871 -, resistance to brain cAMP phosphodiester- -, biological half-life 876 ase 427 -, blood-brain barrier 872 Dichloroisoproterenol, 1-(3',4'-dichloro- -, effects on phenyl)-2-isopropylaminoethanol (DCI) -, - behaviour 495-497 -, effect on -, - blood pressure after intraventricular -, - adrenergic responses of injection 494 -, -- heart 285 -, - brain dopamine 872-873 -, -- skeletal muscle 797 -, - brain noradrenaline 875 -, -- smooth muscle 285 -, - catecholamines in adrenal medulla -, - a-adrenoceptors 314-315 237,241 -, - lipolysis 314 -, - electrocortical activity in -, - noradrenaline uptake 208 -, -- encephale isole preparation 496, -, role as (in) 497 -, - classification of adrenoceptors 285 -, -- intact animals 496, 497 -, - partial adrenergic agonist 314 -, - electromyographic activity 497 -, sympathomimetic activity 314 -, - heart rate after intraventricular in- Diethyldithiocarbamate jection 494 -, effects on -, - spinal cord reflexes 517 -, - behaviour 504 -, - temperature 495 -, - temperature 504 -, - tyrosine hydroxylase activity 873 -, formation from disulfiram 503 -, - urinary excretion of noradrenaline Dihydroergotamine (DHE) 875 -, effect on -, formation 3-4, 187, 849f -, - a-adrenoceptors 328-329 -, - in substantia nigra 8 -,- p-adrenoceptors 316 -, metabolism (in, of) 270, 849f -, - 5-hydroxytryptamine receptors 316 -, - brain 495 -, - lipolysis 316, 387 -, -, formation of Schiff's bases 864, 867 -, pA2 values 326t-327t -, - mast cells 25 -, time for equilibrium 317 -, -, non-enzymatic decarboxylation 868 Dihydro-p-erythroidine, effect on fast EPSP -, -, orally administered 870-880 676 -, -, p-dehydroxylation (bacterial) 877- Dihydroxyephedrine, see a-methyladrenaline 879 3,4-Dihydroxymandelic acid -,-,scheme 871f -, formation from catecholamines 272, -, occurrence in 273f -, - annelids 91 -,O-methylation 272,273f -, - birds 117, 143-144t -, occurrence in -, - coelenterates 86-87 -, - bovine splenic vessels 129-130 -, - ganglioneuroma 918t -, - Helix aspersa 96-97 -, - insects 99 3,4-Dihydroxymandelic aldehyde 272, 273f -,- mammals 3',4'-Dihydroxy-2-methyl propiophenone -, - -, brain 118 (U-0521), inhibitor of COMT 506, 751 -, - -, dog heart 125 3,4-Dihydroxyphenylacetaldehyde 273 f -,- -,eye 121,157t -, pharmacological action 864 -, - -, skin 131 3,4-Dihydroxyphenylacetamide, inhibitor of -, - -, spinal cord 119-120, 154t COMT 506 -, - neuroblastoma 918t 3,4-Dihydroxyphenylacetic acid 273f -, - phaeochromocytoma 905t -, formation -, - plants 852 -, - from catecholamines 273 -, placental barrier 871 -, - in brain 495 -, plasma levels after oral dose 871 -, occurrence in -, side effects 861,863-866 -, - bovine splenic vessels 129-130 -, tool in fluorescence histology 132-133 -, - cerebrospinal fluid after DOPA -, transamination pathways 859f 872-873 -, treatment of -, - Helix aspersa 96-97 -, - miscellaneous diseases 862 65· 1028 Subject Index

L-Dihydroxyphenylalanine (DOPA), treat• 3,4-Dihydroxyphenylpyruvic acid, urinary ment of parkinsonism 4, 188, 860-869 excretion in neuroblastoma 921 -, - -, adventitious movements 864-865 threo-3,4-Dihydroxyphenylserine (DOPS) -, - -, combination with decarboxylase 852f inhibitor 862-863 -, decarboxylation 188,619 -, - -, combination with MAO inhibitor -,effect on 868-869 -, - behaviour 497 -, - -, drug incompatibilities 867-869 -, - blood pressure 191 -, - -, hypotensive effect 863-864 -, - brain noradrenaline 495 -, - -, major side effects 863-869 -, - electrocortical activity 497 -, - -, sexual aspects 866 -, - urinary noradrenaline excretion 852 -, - -, toxic delirium 865 -, precursor of noradrenaline 189 -, urinary excretion 874 3,4-Dihydroxypseudoephedrine -, -, neuroblastoma 921 -, effect on -,-,phaeochromocytoma 913 -, - adrenergic transmission 643t, 650- -, -, various diseases 852 651 -, urinary metabolites 874-875 -, - adrenoceptors 648 Dihydroxyphenylalanine decarboxylase -, - noradrenaline release by sympathetic -, activity after nerve stimulation 642, 643 t -, - denervation 816 -, release (by) -, - immunosympathectomy 822 -, - acetylcholine 634 -, co-factor 3, 188 -,- DMPP 634 -, discovery 2, 187 -, - sympathetic nerve stimulation 621, -, formation of 633t -, - a-methyldopamine 619 -, -, spontaneous, from heart 630 -, - a-methyl-metatyramine 619 -, - tyramine 635 -, - a-methyl-5-hydroxytryptamine 619 -, retention by storage vesiclell 625 -, - metatyramine 619 -, substitution of noradrenaline by 625,637 -, - noradrenaline 619 -, uptake 621 -, identity with 5-HTP decarboxylase 853 Diisopropylfluorophosphate, effect on -, inactivation 188 - mesenteric artery 767 -, inhibition (by) 191-192,496--497 - spleen 767 -, - dihydroxyphenylpyruvic acid 867 3,4-Dimethoxyphenylethylamine -, - a-methyldopa 618, 639 -, akinetic action in animals 858 -, - a-MMT 639 -, effect on adrenoceptors in brain stem 10 -, - phenylpyruvic acid 853-854, 867 4-a-Dimethyl-metatyramine, effect on cate• -, isoenzymes 853 cholamines in brain 499 -, Km value 196 3-a-Dimethyltyrosine, effect on tyrosine -, lack of release by sympathetic nerve hydroxylase 502 stimulation 578 Dimethylphenylpiperazinium (DMPP) -, localisation 187-189 -, adrenergic neurone block 356,773-774 -, meta tyrosine as substrate 878 -, effect on -, occurrence in -, - adrenergic nerve terminals 704 -, - adrenal medulla 3 -, - ganglia 697 -, - human brain 854 -, - ganglionic transmission 700f, 701- -, - nervous system of molluscs 95 703 -, - vascular endothelium of CNS 465 -, - responses to sympathetic nerve stimu- -, substrate specificity 2--4, 188, 619 lation 772-774 Dihydroxyphenylalanine transaminase, for• -, indirect effect on atria 356, 773 mation of dihydroxyphenylpyruvic acid -, release of 859f,867 -, - dihydroxypseudoephedrine 334 3,4-Dihydroxyphenylethanol 273f -, - a-methyladrenaline 334 3,4-Dihydroxyphenylformaldehyde (Proto• -, - a-methylnoradrenaline 334 catechualdehyde), urinary excretion in -, - noradrenaline phaeochromocytoma 913 -, - -, characteristics 769f,770-773 3,4-Dihydroxyphenylglycol 273f -, - -, muscarinic inhibition 768 -, metabolite of catecholamines 272 -, - -, role of calcium 588 t 2-(3,4-Dihydroxyphenyl}-hexanoyl amide, in- -, - -, species differences 772 hibitor of COMT 507 Dinitrophenol (DNP), effect on 3,4-Dihydroxyphenyllactic acid 859f - catecholamine secretion from adrenal 2-(3,4-Dihydroxyphenyl}-pentanoyl amide, medulla 213 inhibitor of COMT 507 - late hyperpolarization 697 3,4-Dihydroxyphenylpyruvic acid 859f - noradrenaline uptake and release on nerve -, conversion to L-DOPA 876 particles 214 -, formation from L-DOPA 867,876 Disulfiram Subject Index 1029

Disulfiram, effect on Dopamine (see also catecholamines), inactiva• -, - adrenergic transmission 643t tion (molluscs) 96-97 -, - behaviour 504 -, inhibition of AP in molluscan ganglia -, - dopamine (brain) 503 97-98 -, - dopamine-p-hydroxylase 192, 503- -, loss from heart after 504 -, - guanethidine 645 -, - -, mechanism of action 192-193 -, - reserpine 645 -, - electro cortical activity 504 -, metabolism 275, 871 f -, - noradrenaline (brain) 503 -, -, brain 495 -, - noradrenaline release after nerve -, -, parkinsonism 859-860 stimulation 643t -, occurrence in -, noradrenaline depletion 629 -, - amphibia 115, 116, 140t-141 t Diurnal variations, see circadian rhythms -, - annelids 81 t, 89-91 DNP, see dinitrophenol -, - arthropods Dog, effect of catecholamines on -, - -, crustaceans 83t,99 - behaviour 470--471 -, - -, insects 84t,99 - electrocortical activity 471--472 -, - basal ganglia, discovery 4 - temperature 483 -, - birds 117, 143t-147t Dopacetamide, effect on tyrosine hydroxylase -, - bony fishes 114 190 -, - carotid labyrinth 19 Dopamine (see also catecholamines) -, - coelenterates 81 t, 86--87 -, accumulation in -, - echinoderms 84t,102 -, - brain after DOPA 495 -, - flatworms 81 t, 87 -, - -, effect of Ro 4-4602 496 -, - invertebrates 79-109 -, - brain, effect of -, - mammals 188 -, -- desmethylimipramine 499 -, - -, adrenal medulla 4,122-123, 158t -, -- imipramine 499 -, - -, blood plasma 132 -, - cat organs after disulfiram 629 -, - -, bovine splenic vessels 129-130 -, - mollusc ganglia 97 -, - -, brain 118-119, 148t-155t,272, -, binding in platelets (parkinsonism) 873 275 -, blood-brain barrier 873 -, - -, carotid body 23, 130, 169t, 922 -, catecholamine concentration after ad- -,- -,eye 121, 157t ministration (adrenal medulla) 237, 241 -, - -, ganglioneuroma, tissue content -, depletion by tyramine 850 918t -, distribution after administration 275 -, - -, gastro-intestinal tract 127-128, -, effect on 165t -, - adrenergic transmission 650 -, - -, heart 125, 159t-160t -, - behaviour -, - -, kidney 161 t -, - -, intracerebral injection 474, 512 -, - -, liver 128, 166t -, - -, intravenous injection 474,476 -,- -,lung 125, 161t -, - -, intraventricular injection 470 -, - -, male sex organs 164t -, - -, stereotype behaviour after 865 -, - -, mast cells 25 -, - electro cortical activity 474 -, - -, neuroblastoma 918t -, - food intake 488--491 -, - -, pancreas 129, 168t -, - guinea pig atria 297 -, - -, peripheral nerves and ganglia -, - heart of molluscs 98, 104 120-121, 156t,787 -, - noradrenaline uptake -,- -,phaeochromocytoma 905t -, - -, isolated nerve particles 208 -, - -, pineal gland 120 -, - -, isolated perfused rat heart 207 -, - -, salivary gland 166t -, - rabbit aortic strip 297 -, - -, skeletal muscle 131, 170t -, - response to adrenergic nerve stimula- -, - -, skin 131 tion after decaborane-14 190 -, - -, spinal cord 119-120, 154t -, - spinal cord reflexes 515 -, - -, spleen 128-129, 167t -, - temperature -, - -, thyroid gland 126, 161 t -, - -, interaction of adrenergic blocking -, - -, urine 132, 170t agents 510 -, - molluscs -, - -, intracerebral injection 484 -, - -, cephalopods 83t,92 -, - -, intracisternal injection 481 -,- -,gastropods 82t,93-95 -, - -, intraventricular injection 481 -, - -, pelecypods 82-83t, 91-92, 95 -, - tyrosine hydroxylation 235 -, - nerve cells (invertebrates) 17 -, - water intake 488--491 -,- protozoans 81t,85 -, formation from DOPA 187 -, - reptiles 116, 142t -, formation of Schiff's bases 867 -, - ribbon worms 89 -, p-hydroxylation, reserpine induced in- -, - venoms of insects 99, 104 hibition 236 -, - vertebrates 110---185 1030 Subject Index

Dopamine (see also catecholamines), potency Dopamine-p-hydroxylase, subcellular distri- (relative to adrenaline) 343t bution, chromaffin cells 540, 542 -, precursor of N -acetyldopamine in insects -, -, chromaffin granule membrane 559 99 -, substrates -, pressor effect in man 863 -, -, dopamine 188-189 -, rate of secretion (adrenal medulla) 123 -, -, metatyramine 619 - receptors -, -, a-methyldopamine 619, 624 - -, mammalian kidney 854 -, -, a-methyl-metatyramine 619, 624 - -, molluscs 97 -, -, a-methyltyramine 619 - -, stimulation of, compulsive gnawing -, -, tyramine 619 865 Dopamine particles (heart) 201 -, release by nerve stimulation 633t Dose ratio, definition 290 -, restoration of response to nerve stimula- tion after reserpine 571 Ear artery (rabbit) -, role as neurotransmitter -, cholinesterase in 780 -, -, basal ganglia 188 -, "degeneration contraction" 817 -, -, eNS 275, 845 -, effect of -, -, discovery 4 -, - acetylcholine 764 -, -, molluscs 92,97-99,104 -, - muscarinic agents on response to sym- -, role in therapeutic effect of DOPA (par- pathetic nerve stimulation 768-769 kinsonism) 872-874 Echinoderms . -, -, discovery 4 -, catecholamines in 84 t, 102-103 -, striatum, parkinsonism 856 -, innervation of muscles 102-103 -, substantia nigra (parkinsonism) 856 Efficacy, definition 288 -, turnover (experimental parkinsonism) Elasmobranchii, chromaffin cells in 18 855 Electrocortical activity, effects of catechol- -, uptake (by, in) amines on 471-478 -, - chromaffin granules 242, 253-254 Electrocortical arousal after -, - brain after intraventricular injection - adrenaline 466-467 - -, curarized animals 477 -, - isolated nerve particles 201 - -, role of hypertension 477-478 -, - isolated rat heart 201 - catecholamines -, - Km value 204 - -, encephale isole preparation 477 -, - platelets (human) 873 - -, intact animals 475-477 -, - striatum, inhibition by anti-parkin- - vasopressin 477 sonian drugs 499 Electrocortical-behavioural dissocation -, urinary excretion 472,474 -, -, dependence on pH 855 Electron dense-cored vesicles, in -, -, neuroblastoma 921 - cholinergic nerve endings 19-20, 37 -, -, parkinsonism 855 - chromaffin cells of -, -, phaeochromocytoma 913 -- carotid body 23 "Dopamine granules" (adrenal medulla) -- suprarenal bodies 18 253-254 - nervous tissue of molluscs 95-96 Dopamine-p-hydroxylase - non-chromaffin cells of carotid body 23 -, activity (after, in) 189 Electron lucent vesicles, in -, - chemical sympathectomy 826 - cholinergic nerve endings 18-20, 37 -, - denervation 816 - nervous tissue of molluscs 95-96 -, - molluscs 95 Electron microscopy -, axoplasmic flow 574,602-603 -, catecholamine-containing structures -, chemical properties 189, 193, 576, 580 46-71 -, co-factors 189 -, -, adrenergic nerve terminals 59-U7, -, estimation method 557 823-824, 824f, 825f - inhibitors 192-193,503-504 -, -, identification 46-47 -, Km value 196 -, -, non-terminal axons 67-68, 70-71 -, occurrence in -, -, sympathetic ganglia 67, 70-71 -, - neuroblastoma 917 -, -, - after 6-hydroxydopamine 824- -, - synaptic vesicles 543f, 544, 574, 577, 826 603 -, -, -, effect of nerve growth antiserum -, rate of resynthesis 559 821 -, release from -, -, vesicle fractions 50-54,61,67,214, -, - adrenal medulla 565 215f -, - chromaffin granules 557 -, methods -, - sympathetic nerves 588t, 590 -, -, autoradiography 61, 67, 200, 20lf -, stereospecificity 624, 635 -, -, fixation 17, 25, 26, 47-50, 781 -, subcellular distribution 187, 189, 254 -, -, staining 47-50,823-824 Subject Index 1031

Electromyographic activity, effect of cate• N-Ethylmaleimide (NEM), effect on ATPase cholamines on 491-494 of chromaffin granules 244-245, 259 Electrophysiology of adrenergic neurone -, - catecholamine release from chromaffin 661-715 granules 259 Electroshock, effect on noradrenaline resyn• -, - noradrenaline uptake in isolated nerve thesis 196 particles 213 Eledoisin, ganglionic action 710 a-Ethylnoradrenaline, stimulation of p- Encephale isole preparation, behavioural and adrenoceptors 320 electrocortical arousal after catechol• Excitatory junction potential (EJP) amines 476,477 -, effect of catecholamines on 802 End-plate potential (EPP), effects of cate- -, recording in cholamines 801 -, - dog retractor penis 565-566 Enterochromaffin cells in -, - piscine red muscle 802 - mammals 133 -, - vaS deferens 565-566 - urochordates 103 Excitatory postsynaptic potential (EPSP) Environmental lighting, metabolic effects in -, fast EPSP 673-676 pineal gland 428-432, 431 t -, -, effect of Enzyme -, -, - adrenaline 789 - activation versus stimulation 365 -, -, - "non-depolarizing" ganglionic - inactivation versus inhibition 365 blocking agents 676 - induction, definition 364 -, -, electrogenesis 674-675 - repression, definition 364 -, late slow EPSP 684 Ephedrine -, miniature EPSP 675 -, cocaine-resistant accumulation 351 -, -, effect of adrenaline on 789 -, effect on -, slow EPSP 680 -, - p-adrenoceptors 301 Exocytosis -, - behaviour after intracisternal injec- -, adrenal medulla tion 511 -, -, historical aspects 563 -, - noradrenaline uptake 208 -, -, ultrastructural observations 563- - isomers, effect on 564,563f -- muscarinic receptors 301 -, anterior pituitary gland 563 -- nictitating membrane 351 -, corpus cardia cum 563 -- rat vas deferens 346 -, in vitro models 255-257 -, stimulation of adrenal medulla 587t -, rate of 594 Epinine (N -methyldopamine) -, role of -, occurrence in Bufo marinus venom 115 -, - Brownian motion of vesicles 583- -, potency (relative to adrenaline) 343t 584 -, substrate for MAO 864 -, - calcium 589-592 EPP, see end-plate potential -, - type of vesicle 578-582 EPSP, see excitatory postsynaptic potential -, subcellular mechanisms 582-605 Equations for Eye, mammalian - effect of agonist, acting on specific type of -, adrenergic innervation of 121 receptors 288 -, catecholamines in 121, 157t - irreversible antagonism 292-293 - reversible competitive antagonism 290 Fat cell ghosts, technique of preparation 379 - -, two antagonists present 315 FCCP, see carbonyl cyanide p-trifluoro• - saturable uptake model system 308- methoxyphenylhydrazone 309,311 Feedback control mechanism for noradren- Ergometrine, dopamine antagonist in mol• aline synthesis 187, 190, 194 luscs 97-98 FFA, see free fatty acids Ergot alkaloids, role in classification of Flatworms, catecholamines in 81 t, 87-88 adrenoceptors 284 Fluorescence histochemical method, see Ergotamine, effect on formaldehyde-fluorescent reaction - a-receptors 353 Fluorescence microscopy, see formaldehyde- - smooth muscle preparations 314 fluorescent reaction Ergotoxine Fluoride, effect on -, effect on neuromuscular junction 800 - adenyl cyclase 368 -, role in discovery of adrenoceptors 9 - noradrenaline uptake and release on nerve a-Ethoxydopacetamide, inhibitor of COMT particles 213 507 Food intake Ethylenediaminetetraacetic acid (EDTA), -, effects of catecholamines on 488-491 effect on catecholamine oxidation 318 -, -, stereospecificity 512 N -Ethylmaleimide (NEM) -, relation to thermoregulation 490-491 -, antilipolytic effect 385f Formaldehyde-fluorescent reaction, in -, effect on - adrenergic nerves (after) 1032 Subject Index

Formaldehyde-fluorescent reaction, in adren• Glucagon, effect on liver ergic nerves (after), axoplasmic noradren• - -, adenyl cyclase 367-369 aline 571 - -, calcium in 377 - -, corbadrine isomers 621 - -, gluconeogenesis 371-373 -- 6-hydroxydopamine 826 - -, lipid metabolism 373-375 -- immunosympathectomy 821 - -, metabolic processes 367 - -, uptake experiments 197,200 - -, potassium fluxes 376 - amphibia 114--116 - -, protein synthesis 375-376 - birds 117 - pyruvate transport in mitochondria 372 - bony fishes 114 - urea production 372,374 - catecholamine-forming cells 132-133 - white adipose tissue - chromaffin cells 5, 17, 23 - -, adenyl cyclase 379 - invertebrates 79, 80, 86-95, 99-104 - -, glucose transport 383 - mammals Glucocorticoids - -, adipose tissue 130 -, effect on - -, adrenal gland 122 -, - liver glycogen synthesis 370-371 - -, eye 121 -, - liver lipid metabolism 373 - -,heart 125 -, induction of - -, intestine 128 -,- PNMT - -, liver 128 -, - -, normal chromaffin tissue 32, 124, - -,lung 125 232 - -, male sex organs 126-127 -,- -,phaeochromocytoma 232 - -, pancreas 129 -, - tyrosine transaminase 375 - -, salivary glands 129 -, "permissive" effect 379 - -, skeletal muscle 131 Gluconeogenesis in liver 371-373 - -, spleen 129 Glucose-6-phosphate, effect on liver glycogen - reptiles 116 synthetase 370 Fowl, effects of catecholamines on Glucose transport in white adipose tissue 383 - behaviour 470--472 L-Glutamate, effect on ganglionic trans• - temperature 485 mission 710 Free fatty acids (FFA) Glycerol, release by catecholamines 389 -, effect on Glycogen metabolism, regulation by auto- -, - liver metabolism 373-374 nomic nerves 371 -, - oxygen uptake 412--414 Glycogen phosphorylase in -, - urea production 374 - cardiac muscle -, release by catecholamines 389 - -, activation versus inotropic response -, uncoupling of oxidative phosphorylation 395-396 412--415,414f - -, calcium dependence 394-396 -, uptake by liver 373 - -, effect of anoxia 399 Frog (see also amphibia), catecholamines in - liver 10, 369-371, 378f 115,140-141 t - skeletal muscle 10, 400f, 401 Fructose diphosphate, effect on triglycerid - -, activation by electrical stimulation lipase 388 402--403 - smooth muscle 405--407 GABA, see I'-aminobutyric acid - -, activation after Ganglioneuroblastoma 900 - -, - p-adrenoceptor agonists 406--407 Ganglioneuroma - -, - contraction 407 -, catecholamines in 918t Glycogen synthetase in -, -, release 921 - cardiac muscle 393 - liver 369-371, 378f -, -, subcellular distribution 919 -,occurrence 900,917 - skeletal muscle 400f,401 - -, effect of electrical stimulation 403 Gastro-intestinal tract, mammalian, cate• Goat, effects of catecholamines on tempera• cholamines in 127-128, 165t ture 484 GD 131, see N-cyclohexyl-methyl-N-ethyl-p• Goldblatt clamp method, effect on catechol• chloroethylamine amines in blood vessels 130 Glomus jugulare, catecholamines in tumours Golgi apparatus of chromaffin cell 599- of 922,923t 600, 599f Glucagon, effect on Gonadotrophins, effect on PNMT activity 32 - blood pressure of phaeochromocytoma Granular vesicles, see synaptic (granular) patients 915 vesicles - heart Guanethidine - -, adenyl cyclase 392-393 -, effect on - -, '5ea uptake 396 -, - adrenergic false transmitters 645- - insulin secretion 419--422 646 Subject Index 1033

Guanethidine, effect on adrenergic nerve Hexamethonium, effect on responses to sym- terminals 712-713,777 pathetic nerve stimulation 764 -, - ganglia 712 n-Hexylamine, indirect effect 352-353 -, - noradrenaline Histamine -, -- uptake 209 -, antilipolytic effect 385f -, -- storage in nerve granules 219 -, effect on -, -- release 277,774 -, - aortic strip 341 -, indirect effects 355 -, - brain adenyl cyclase 427 -, membranal uptake of 355 -, - catecholamine(s) -, release from adrenergic nerves 618 -, -- appearance in gastric juice 128 Guanosinetriphosphate (GTP), in chromaffin -, -- release (from, in) granules 542 -, --- adrenal medulla 587t, 914- Guinea-pig, effects of catecholamines on 915 - behaviour 475,476 -, --- phaeochromocytoma 914--915 - electrocortical activity 475 -, - dog adrenal medulla, dependence on perfusion medium 834 H 35/25, see 1-(4-methylphenyl)-2-isopropyl- -, - ganglia 709 aminopropanol -, - noradrenaline H 44/68, see a-methyltyrosine dimethyl ester -, -- uptake 214 p-Haloalkylamines -, -- storage in nerve particles 219 -, a-adrenergic blocking activity 10 -, occurrence in -, classification of adrenoceptors 284--285 -, - ganglioneuroma 919 Haloperidol -, - molluscs 92 -, effect on -, receptors, effect of adrenergic antagonists -, - dopamine receptors 854, 865 on 316 -, - dopamine uptake by platelets 873 DL-homocysteate, ganglionic depolarization -, treatment of Gilles de 100 Tourettes disease 710 865 Homocysteine, occurrence in phaeochromo• Harmalol, treatment of parkinsonism 868 cytoma 906 Harmine Homoserine, urinary excretion in neuro- -, effects on sympathetic ganglia 788 blastoma 921 -, treatment of parkinsonism 868 Heart Homovanillic acid (HVA) 857f -, catecholamine-containing cells, fine-struc- -, cerebrospinal fluid (in, after) ture 52t -, -, assay 859 -, chromaffin cells 17-18,21,125 -, - depression 862 -, frog, a- and p-adrenoceptors 299, 320 -, - DOPA administration 872-873 -, inotropic response -, - parkinsonism 859-860 -, - after acetylcholine 769 -, formation 270, 273f, 495 -, -, relationship to phosphorylase acti- -, occurrence vation 391,395-399 -, -, basal ganglia (parkinsonism) 856 -, mammalian, catecholamines in 125, -, -, Helix aspersa 96, 97 159t-160t -, -, neuroblastoma 918t, 919 -, noradrenaline release 768-778 -, urinary excretion (after, in) 858 -, -, effect of acetylcholine 769 -, - L-DOPA 874,876 -, response to sympathetic nerve stimulation -, - malignant pha.eochromocytoma 912, after 913 -, - anticholinesterases 767 -, - neuroblastoma 921 -, - hemicholinium 765 -, - parkinsonism 855 -, sympathectomy, effects of 815, 821, -, - tyramine 850 826f, 827-830 iso-Homovanillic acid (3-hydroxy-4-meth- Hemicholinium, effects on responses to sym- oxyphenyl acetic acid) 857f pathetic nerve stimulation 765 -, urinary excretion 857 Hexamethonium, effect on -, - in parkinsonism 858 - adrenergic nerve terminals 704 Hydergin, effect on noradrenaline uptake - ganglia 208-209 - -, antidromic AP 671 Hydrocortisone, effect on - -, depolarization 695 - lipid metabolism (liver) 373 - -, fast EPSP 676 - PNMT activity 32 - -, nicotinic late hyperpolarization 697 m-Hydroxybenzyloxyamine (NSD 1024). - noradrenaline effect on dopamine-p-hydroxylase 192 -- uptake 209 P-Hydroxy-N -t-butyl-2,4-dichlorophenethyl• -- release by nicotinic drugs 767-771 amine, effect on lipolytic response 314 - responses to 3-Hydroxycinnamic acid, effect on DOPA -- nicotinic drugs 764 decarboxylase 191 1034 Subject Index

5-Hydroxydopa p-Hydroxyphenylpyruvic acid, urinary ex- -,effect on cretion after L-DOPA 876 -, - adrenergic nerve terminals 823 5-Hydroxytryptamine (5-HT) -, - adrenergic transmission 643t -, depletion by -, - noradrenaline -,- DOPA 879 -, -- pressor response 646 -, -- plus Ro 4-4602 496 -, -- release by sympathetic nervestim- -, - reserpine 5 ulation 643t -, effect on -, -- response of nictitating membrane -, - adrenal medulla 587 t 646 -, - catecholamine uptake 245 -, loading of hypothalamic vesicles 68 -, - dopamine uptake by platelets 873 5-Hydroxydopamine -, - nictitating membrane 356 -, effect on -, - noradrenaline -, - adrenergic nerve terminals 823-824, -, -- storage in nerve particles 219 824f -, -- uptake 214 -, - adrenergic transmission 650 -, - sexual activity 866 -, - number of vesicles in eNS 64-65 -, - sympathetic ganglion 708-709 -, electron microscopic evidence of vesicular -, - temperature 486 retention 622 -, electron microscopic evidence of vesicular -, loading of synaptic vesicles 58, 60, 68 retention 58, 622 -, O-methylation 620 -, increased concentration after sympathec- - release by nerve stimulation 632, 633t tomy 822-823 6-Hydroxydopamine 856f -, indirect effects 356 -, aetiology of parkinsonism 856, 861 -, occurrence in -, effect on -, - annelids 89-91 -, - adrenergic nerve terminals 64, 666, -, - carotid body 23, 922 775,823-824,825f,826 -, - crustaceans 99-100 -,- brain 828--829 -, - flatworms 87-88 -, - dopaminergic neurones 857 -, - hypothalamus (parkinsonism) 856 -, - neuronal uptake of noradrenaline 737 -, - molluscs 92, 94, 95 -, - sympathetic ganglia 824-826 -, - nerve cells 17 -, - tyrosine hydroxylase 194 -, - phaeochromocytoma tissue 905t - formation 823 -, - thyroid tumour 901 -, indirect effect 356 -, - urochordates 103 -, liberation as false transmitter 827 - receptors, effect of adrenergic antagonists -, mechanism of action 829-830, 829f 316 -, noradrenaline depletion 826-828 -, synthesis in pineal gland 206 -, -, protection against, by metaraminol - uptake by 878 -- adrenal medullary granules 243 - supersensitivity to noradrenaline 737 -- adrenergic nerves 206, 208, 622 -, treatment schedules 827-828 -- platelets 205 -,uptake 827,827f 5-Hydroxytryptamine N -acetyltransferase, m-Hydroxyephedrine, potency [relative to regulation of melatonin synthesis 430, adrenaline] 343 t 431t,432 p-Hydroxyephedrine, potency [relative to 5-Hydroxytryptophan (5-HTP) adrenaline] 343 t -, protection against harmaline tremor 880 5-Hydroxyindoleacetic acid, in cerebrospinal -, substrate of DOPA decarboxylase 188 fluid after L-DOPA 879 -, therapeutic effects in parkinsonism 880 4-(2-Hydroxy-3-isopropylaminopropoxy)-in• 5-Hydroxytryptophan decarboxylase, acti• dole (LB 46), p-adrenergic antagonist 307 vity after surgical denervation 823 3-Hydroxy -4-methoxyphenylacetic acid, see Hyperpolarizing afterpotential, following iso-homovanillic acid antidromic ganglionic spike 671--673 4-Hydroxy-3- methoxyphenyllactic acid 859 f Hypertensive crisis -, urinary excretion after DOPA 876, 877 - after DOPA plus MAO inhibitor 869 4-Hydroxy-3-methoxyphenylpyruvic acid - in phaeochromocytoma patients 913, 859f 915 p-Hydroxynorephedrine, see a-methyloctop• Hyperthermia after amine - adrenaline 482-484 p-Hydroxyphenylacetaldehyde, in neuro• - DOPA 495 blastoma 917 - dopamine 481 m-Hydroxyphenylacetic acid, urinary ex• - isoprenaline 481 cretion after L-DOPA 877-878 - noradrenaline 481-488 -, suppression by neomycin 878 Hypogastric nerve p-Hydroxyphenylpropanolamine, potency -, catecholamines in 124 [relative to adrenaline] 343t -, cholinergic fibres in 762 Subject Index 1035

Hypogastric nerve, chromaffin cells in 124 Insulin, effect on chromaffin granules 33, -, effect of cutting on noradrenaline in 600 -, - accessory male genital glands 815 -, - glucose transport (cardiac muscle) -, - vas deferens 815 399 Hypophysectomy, effect on -, - glycogen metabolism (skeletal muscle) - chromaffin granules 600 404 - noradrenaline synthesis 195-196 -,-liver - PNMT activity 32, 124 -, -- enzyme induction 375-376 Hypothalamus -,- - gluconeogenesffi 372 -, adrenaline in 486 -,- - glycogen 370 -, electrical stimulation, effect on shivering -, - noradrenaline uptake 214 493-494 -, - white adipose tissue -, electron micrographs 6lf-66f -, -- amino acid transport 383 -, 5-hydroxytryptamine in 486 -, -- glucose transport 383 -, injection of catecholamines, effect on -, -- lipolysis 382,385f -, - behaviour 474,476 - secretion, role of -, - food and water intake 488-491 -- adrenoceptors 319 -,- temperature 482-484,485f -- calcium 421 -, noradrenaline -- catecholamines 419-423 -, - content 486 -- sympathetic tone 422 -, - turnover 486 INPEA, see N-isopropyl-p-nitrophenyl- -, - uptake 464 ethanolamine -, role in temperature regulation 486-488 Intestine -, types of vesicles in 63 -, catecholamine(s) Hypothermia after -, - containing cells 52t - adrenaline 481-484 -, - content 127-128, 165t - dopamine 481 -, -, effect on motility 792-796 - isoprenaline 485 -, response to sympathetic nerve stimu- - a-methylnoradrenaline 485 lation after - noradrenaline 481-485 -,- DMPP 773 Hypoxanthine, catecholite of adenine nucleo• -, - hemicholinium 765 tides 541 -, types of adrenoceptors 285-286, 298 Intrinsic activity 288 Imipramine, effect· on Intrinsic efficacy 288 - central actions of noradrenaline 501 Invertebrates - disappearance from brain of -, catecholamines in 79-109 -- catecholamines 499 -, chromaffin cells in 17 -- 5-hydroxytryptamine 500 Iodoacetic acid, effect on - uptake of - catecholamine secretion from adrenal -- catecholamines 499 medulla 213 -- 5-hydroxydopamine 827 - noradrenaline uptake and release on nerve -- 5-hydroxytryptamine 500 particles 213 -- noradrenaline 212, 218 Iodobenzoate, effect on noradrenaline uptake Immunosympathectomy 818-823, 830- and release on nerve particles 213 832 3-Iodo-L-tyrosine, effect on tyrosine hydro- -, effect on xylase 190 -, - adrenergic nerve fibres of adipose Iproniazid tissue 130 -, discovery as MAO inhibitor 7 -, - behaviour of rat 821 -, effect on (in) -, - noradrenaline uptake 198, 737 -, - noradrenaline uptake in brain 213 -, limitations of 830-831, 835 -, - oculogyric crises 861 -, supersensitivity to noradrenaline 7.) 7 Iris Indole alkylamines, ganglionic stimulation -, catecholamine-containing cells 52t 708-709 -, "degeneration contraction" 817 Inhibitory postsynaptic potential (IPSP) -, dilator muscle, innervation 763 -, effect of -, noradrenaline content after -, - catecholamines 682,778-792 -, - chemical sympathectomy 828 -, - dibenamine 682, 790-791 -, - surgical denervation 815 -,- ouabain 683,789 Isolated tissues -, electrogenesis 678, 680, 789 -, change in sensitivity to adrenergic Insulin agonists 295-297 -, effect on -, loss of drug from bathing solution 317- -, - catecholamine excretion in phaeo- 318 chromocytoma 913 Isoniazid, formation of Schiff's base with -, - chromaffin cells 16,546, 547t pyridoxal phosphate 868 1036 Subject Index

Isoprenaline, see isopropylnoradrenaline Isopropylnoradrenaline (isoprenaline, iso• l-Isopropylamino-2-hydroxy-3- (o-allyloxy• proterenol) [see also catecholamine(s)], phenoxy)-propane (Ciba 39089 Ba), effect potency [relative to (-)-noradrenaline] on -,-,a-adrenoceptors 326-327t, 328- - acetylcholine receptors 316 329 - histamine receptors 316 -, -, p-adrenoceptors 321-325,322t 4-(2-Isopropylamino-l-hydroxyethyl) -, selective agonist for p-adrenoceptors 299 methanesulfonanilide (sotalol, MJ 1999) -, supersensitivity after -, effect on -, - block of COMT 750-751 -, - acetylcholine receptors 316 -, - denervation 834 -, - histamine receptors 316 -, - phenoxybenzamine 748-749 -, intrinsic sympathomimetic activity 314 -, uptake (by) - isomers -, - adrenergic nerve granules 197-198 - -, as isoprenaline antagonists 310-312 -, - axonal membrane 197-198 - -, effect on insulin secretion 421 -, -, extraneuronal 303,310,748-751 -, pA2-values 322-323t, 325 -, - isolated nerve particles 201 Isopropylmethoxamine, for distinction of -, -, lack of membranal 350 p-adrenoceptors 286 -, -, vesicular 350 N -Isopropyl-p-nitrophenylethanolamine 4-Isopropyltropolone, effect on dopamine-p• (INPEA) hydroxylase 193 -, effect on Isoproterenol, see isopropylnoradrenaline -, - lipolysis 387 Isoxsuprine, interaction with propranolol -, - 5-hydroxytryptamine receptors 316 299-300 -, intrinsic sympathomimetic activity 314 -, isomers, effect on a-adrenoceptors 315 Juxta glomerular apparatus, fine structure of -, pA2 values for p-adrenergic blockade catecholamine-containing cells in 52t 322t Isopropylnoradrenaline (isoprenaline, iso- KA-value of proterenol) [see also catecholamine(s)] - adrenergic agonists 288, 289 -, effect (action) on (of) - adrenergic agonists during presence of an -, - behaviour irreversible antagonist 292-293, 293f -, - -, interaction of adrenergic blocking - muscarinic agonist 292 agents 508 KB-value -, - -, intracerebral injection 474, 512 -, erroneous estimates of 296, 307-313, -, - -, intracisternal injection 469-470, 313-316,317 511 -, estimation of, for classification of -, - -, intravenous injection 476 -, - agonists 290-291 -, - -, intraventricular injection 470, -,- receptors 290--291 512 -, - sub-types of p-adrenoceptors 321- -, - blood pressure after intraventricular 325,322t injection 494, 511 Kidney, mammalian -, - EPP 801-802 -, adrenergic innervation 126 -, - food intake 490 -, catecholamine content 126, 161 t -, - -, interaction of adrenergic blocking -, - after immunosympathectomy 821 agents 510 Kinetic constants (Michaelis-Menten) of -, - ganglionic resting potential 788- - catecholamine uptake 203t 792 - enzymes involved in catecholamine syn- -, - growth of salivary glands 425-426 thesis 196 -, - infusion in man 494 Kitten, effects of catecholamines on behavi• -, - lipolytic response 312-313 our 475,476 -, - neuromuscular transmission 798- Km-values, see kinetic constants 800 K5 592, see 1-(3-methylphenoxy)-2-hydroxy- -, - noradrenaline uptake in isolated per- 3-isopropylaminopropane fused rat heart 207 -, - skeletal muscle 796-798 Lacrimal gland, fine structure of catechol- -, - temperature amine-containing cells in 52 t -, - -, interaction of adrenergic blocking Lactate dehydrogenase agents 510 -, molecular diameter 562 -, - -, intracerebral injection 485 -, lack of release from chromaffin cell 562 -, - -, intraventricular injection 481 Late negative wave (LN-wave) in -, facilitation of ganglionic transmission - superior cervical ganglion 675f 788 - sympathetic ganglia 680-681 -, ganglionic depolarization 708 LB 46, see 4-(2-hydroxy-3-isopropylamino• -, hypotensive effect, reversed by pilocar- propoxy)-indole pine 351 Lecithin, chromaffin granules 593 Subject Index 1037

Leptodactyline (m-hydroxyphenylethyl- Mast cells trimethylammonium) -, chromaffin reaction 16,25 -, isolation from amphibia 133 -, dopamine-containing 25 -, pharmacological properties 133 -, occurrence in ruminants Leucocyte granules -, - gastrointestinal tract 127-128 -, Brownian motion of 584 -, - heart 125 -, rate of exocytosis 594 -, - liver 128, 166t Light exposure, see environmental lighting -,- lung 125 Lipid(s) -, - skeletal muscle 131 -, chromaffin granules 539, 558-559 -, - thyroid gland 126 -, metabolism in liver 373-375 -, role in noradrenaline Lipolysis -, - storage 25 -, brown adipose tissue 409, 410f -, - synthesis 25 -, isolated fat cells, effect of p-adrenergic McN -A-343, see 4-(m-chlorophenylcarba• antagonists 312-313 moyloxy)-2-butynyltrimethylammonium -, liver 374-375, 378f chloride -, white adipose tissue 379, 380f, 385f Mecamylamine, effect on -, -, interference of serum albumin 318, - antidromic ganglionic AP 671 325 - fast EPSP in sympathetic ganglia 676 Liver, mammalian Median eminence, types of vesicles in 63 -, adrenergic innervation 128 Melanin -, catecholamine content 128, 166t - formation 8, 49-50 -, - after immunosympathectomy 821 - forming cells, tyrosinase in 8 LN-wave, see late negative wave -, substantia nigra cells in parkinsonism Lithium, effect on 857 - nicotinic ganglionic actions 696-697 Melanophores - posttetanic hyperpolarization 691 -, electron microscopy of 49-50 Lobeline, ganglionic actions 695, 698, 701 -, occurrence 25 Local anaesthetics, effect on Melatonin, synthesis in pineal gland 428- - adrenergic nerve terminals 589, 776 432, 430f, 431 t - chromaffin cell 587, 589 Membrane capacitance of adrenergic nerve - ganglia (electrophysiology) 712 cell body 664t, 667 Locus coeruleus, types of vesicles in 63-64 Membrane potential, adrenergic nerve cell LSD, see lysergic acid diethylamide body 664t,666-667 Lung, mammalian Mental disease, noradrenaline in cerebro• -, catecholamine content 125, 161 t spinal fluid 120 -, - after immunosympathectomy 821 Mercuribenzoate, effect on noradrenaline -, fine structure of catecholamine-contain- uptake and release on nerve particles 213 ing cells 52 t Mesenteric artery, vessels Luteinizing-hormone releasing factor, dis• -, noradrenaline content after 6-hydroxy• charge by dopamine 866 dopamine 831 Lysergic acid diethylamide (LSD), effect on -, response to sympathetic nerve stimulation noradrenaline after - uptake 213 -, - anticholinesterases 767 - storage 218 -,- DMPP 773 Lysolecithin Metabolic inhibitors, effect on catecholamine -, action on uptake in chromaffin granules 213 -, - heart 592 Metabolic processes -, - membranes 593 -, regulation (general) 364t -, occurrence 592,593t -, skeletal muscle 402-405 -, role in catecholamine release 251,592- Metamphetamine, effect on adrenal medulla 594 587t Lysosomal enzymes, secretion from adrenal Metanephrine 273f gland 551 -, electro cortical activity after 477 -, formation 272-276 Magnesium, role in catecholamine release -, indirect effect on rabbit ileum 350 from adrenal medulla 586-589, 587 t -, inhibition of extraneuronal uptake 748 Malabsorption syndrome, MAO activity in -, metabolism 273, 275 intestinal mucosa 850-851 -, occurrence in Mammals -, - ganglioneuroma 919 -, catecholaminesin 117-133,148t--170t -, - neuroblastoma 919 -, chromaffin cells in 20--22 -, - phaeochromocytoma 905t Man, effects of catecholamines on behaviour -, urinary excretion 275,903 470 -, -, neuroblastoma 921 Mania, urinary excretion of dopamine 855 -, -, phaeochromocytoma 912 1038 Subject Index

Metaoctopamine, formation in vivo 626 4-Methoxy-3,5-dihydroxyphenylalanine, Metaraminol effect on -, effect on - adrenergic transmission 643 t -, - adrenergic transmission 651 - noradrenaline release 643 t --, - nictitating membrane 344 - response to noradrenaline 646 -, - noradrenaline 4-Methoxy-3,5-dihydroxyphenylethylamine -, -- responses 646-647,649 -, effect on adrenergic transmission 650 -, -- synthesis 639-641 - electron microscopic evidence of vesicular -, -- uptake 207-208, 649 retention 622 -, - rat vas deferens 346 -, formation 626 -, - small granular vesicles 58 -, indirect action 648 -, formation 626, 628 -, O-methylation 620 -, indirect action 344, 346, 648 -, release by nerve stimulation 633t -, loss from 3-Methoxy-4-hydroxy compounds, see also -, - heart 625, 632, 645 4-Hydroxy-3-methoxy ... -, - salivary gland 630, 632 3-Methoxy-4-hydroxymandelic acid (VMA) -, noradrenaline substitution by 205-206, 273f 625,637-638 -, electrocortical activity after 477 -, optical isomers (enantiomorphs) -, metabolite of catecholamines 270, 272, -, -, absolute configuration 623 273f, 276, 277 -, -, affinity for retention 622 -, occurrence in -, -, effect on blood pressure 623 -, - Helix aspersa 97 - -, formation in vivo 624-625 -, - neuroblastoma tissue 918t - -, loss from heart 625 -, - phaeochromocytoma tissue 905t - -, membranal uptake 622 -, urinary excretion (after) 6, 277 -,potency 343t, 344 -, - L-DOPA 874-875 -, release (by) -, - neuroblastoma 920 -, - nerve stimulation 631, 633t, 635 -, - phaeochromocytoma 848, 912 -, -, spontaneous, from heart 630 -, - reserpine 193, 236 -, - tyramine 635 3-Methoxy -4-hydroxyphenylalanine, urinary -, resistance towards metabolizing enzymes excretion in neuroblastoma 921 622 3-Methoxy -4-hydroxyphenylethanol -, metabolite of catecholamines 273f -, retention by -, - adrenergic neurones 188,621 -, urinary excretion in neuroblastoma 921 3-Methoxy -4-hydroxyphenylethylamine, -, - particulate fraction (heart) 645 urinary excretion in phaeochromocytoma -, shift between pools 630, 645 913 -, uptake 3-Methoxy-4-hydroxyphenylglycol 273f -, -, characteristics 622-623 -, metabolite of catecholamines 272-273, -, -, chromaffin granules 243 276-277 -, -, effect of sympathectomy 621 -, occurrence in -, -, membranal 622, 649 -, - brain 469 -, -, vesicular 201,622,645 -, - neuroblastoma 917,919 -, urinary excretion after cold exposure -, - phaeochromocytoma 906 632 -, urinary excretion 277 threo-Metaraminol, actions 625 -, -, neuroblastoma 921 Metatyramine, urinary excretion after -,-,phaeochromocytoma 912 L-DOPA 878 3-Methoxytyramine 273f Metatyrosine 878f -, urinary excretion in -, decarboxylation 188, 619 -, - neuroblastoma 921 -, excitatory effect 878 -, - phaeochromocytoma 913 -, hydroxylation 189 a-Methyladrenaline -, hypertensive response to 879 -, diastereomers 624 Methacholine, effect on -, effect (on) - adrenal medulla 587t -, - adrenergic transmission 643t, 650- - noradrenaline release 768 651 - sympathetic ganglia -, -, cardiovascular 648 -- depolarization 705-706 -, - nictitating membrane 343t -- hyperpolarization 704 -, - noradrenaline release by nerve stimu- - tracheal strip 301 lation 642,643t Methoxamine -, fluorescence in adrenergic nerves 621 -, effect on nictitating membrane 342 -, formation 628 -, -, cocaine-treated 738 -, release (by) -, -, denervated 734 -, - nerve stimulation 631-632,633t, -, lack of neuronal uptake 307, 350 635 Subject Index 1039 a-Methyladrenaline, release (by) spontaneous a-Methyldopamine, optical isomers, p-hydro- 630 xylation 624 -, - tyramine 635 -, -, retention by heart 626 -, substitution of catecholamines 625, 637 -, potency 343t erythro-a-Methyladrenaline, see a-methyl- -, release by nerve stimulation 632, 633t adrenaline (-)-a-Methyldopamine (see also a-methyl• N-Methyladrenaline 849f dopamine, optical isomers) -, formation 231 -, effect on atrial response to noradrenaline -, metabolism 270, 272 649 -, occurrence in adrenal medulla 123, 231 -, release by nerve stimulation 633 t, 649- a-Methylated amines (see also individual 650 amines), uptake into brain 466 -, substitution of noradrenaline 637 a-Methylated amino acids (see also a-methyl- N-Methyldopamine, see epinine dopa, a-MMT, a-methyltyramine) 3-0-Methyldopamine, see 3-methoxytyr- -, decarboxylation 4 amine -, depletion of brain 4-Methyl-a-ethyl-meta-tyramine, depletion -, - dopamine 497 of brain catecholamines 500 -, - 5-hydroxytryptamine 497 N-Methyl-N-(2-hydroxybenzyl)-hydrazine threo-N-methylcorbadrine, see dihydroxy- (NSD 1039), effect on pseudoephedrine - DOPA decarboxylase 192 a-Methyldopa - endogenous catecholamines 192 -, central hypotensive effect 192, 652, 864 N-Methyl-N(3-hydroxybenzyl)-hydrazine -, decarboxylation 188, 619, 635 (NSD 1034), effect on -, effect on - DOPA decarboxylase 192 -, - adrenergic transmission 643t, 651 - dopamine-p-hydroxylase 192 -, - blood pressure 651-652 - endogenous catecholamines 192 -,- brain a-Methyl-5-hydroxytryptophan, decarboxy• -, -- dopamine 626, 638 lation 619 -, -- 5-hydroxytryptamine 626 5-Methylisoxazole 3-carboxylic acid, anti- -, -- noradrenaline 191, 497, 626, 637 lipolytic effect 385f to 638 N-Methylmetadrenaline 849f -, - DOPA decarboxylase 191 N -Methylmetanephrine -, - noradrenaline -, formation from -, -- concentration of peripheral organs -, - metanephrine 231 191,636-638 -, - N-methyladrenaline 123,231 -, -- excretion 642 -, occurrence in -, -- release by nerve stimulation 643t -, - normal human urine 231,232 -, -- synthesis 639-642 -,- phaeochromocytoma 232,906,912 -, - response to noradrenaline of a-Methyl-metatyramine -, -- blood pressure 646 -, effect on noradrenaline -, -- heart 646 -, - synthesis 639-640 -, -- nictitating membrane 646-647 -,- uptake 208 -, - spinal cord noradrenaline 641 -, formation 191,628 -, - tyrosine hydroxylase 190 -, optical isomers, P-hydroxylation 624 -, - vascular resistance 651 a-Methyl-metatyrosine (a-MMT) -, O-methylation 620 -, decarboxylation 188,619 N-Methyl DOPA, lack of decarboxylation -, effect on 2-3, 188 -, - adrenergic transmission 644,651 3-0-Methyl DOPA 859f,877f -, - brain -, formation from L-DOPA 876-877 -, -- dopamine 638 -, metabolism 877 -, -- noradrenaline 497,628 a-Methyldopamine -, - DOPA decarboxylase 191 -, affinity to uptake sites 188, 649 -, - noradrenaline -, effect on response of vas deferens to nor- -, -- concentration of peripheral organs adrenaline 647 191, 628, 636-638 -, formation 191, 626 -, -- pressor response 646 -, indirect action 648 -, -- synthesis 639-641 -, O-methylation 620 -, -- uptake 208 -, optical isomers -, - small granular vesicles 58 -, -, absolute configuration 624 -, - spinal cord noradrena.line 641 -, -, effect on -, - tyrosine hydroxylase 190 -, -, - adrenergic transmission 643 t, 650 -, - urinary excretion of -, -, - noradrenaline release by nerve -, -- 3-methoxy-4-hydroxyphenyl- stimulation 642, 643t glycol 640 -, -, histofluorescence 621 -, -- noradrena.line 640 1040 Subject Index a-Methylnoradrenaline a-Methylnoradrenaline, uptake, vesicular - diastereomer(s) 201,622,645 - -, absolute configuration 623 -, urinary excretion after a-methyldopa - -, erythro-form 623, 624 624,634 - -, threo-form 624 a-Methyloctopamine -, effect (on) -, effect on (of) -, - adrenergic transmission 650-651 -, - adrenergic transmiBBion 651 -, - behaviour (after) -, - immunosympathectomy on retention -, -- intracerebral injection 474, 512 of 621 -, -- intravenous injection 475-476 -, formation 626, 628 -, -- intraventricular injection 470- -, indirect action 648 472,512 . -, loss from heart after guanethidine 646 -, - -, interaction of phenoxybenzamme -, release by nerve stimulation 631-632, 507-509 633t -, - blood pressure 647-648 Methylphenidate, indirect effect on nictitat• -, -- after infusion into hypothalamus ing membrane 354 495 1-(3-Methylphenoxy)-2-hydroxy-3-isopropyl -, -, cardiovascular 648 aminopropane (K6 592), effect on -, - electromyographic activity 475f, - 5-hydroxytryptamine receptors 316 492-493,493f - lipolysis (white adipose tissue) 386 -, - electro cortical activity 474-477, a-Methylphenylalanine 475f -, effect on DOPA decarboxylase 191 -, - -, interaction of phenoxybenzamine -, formation of metaraminol 628 507-508 1-(4-Methylphenyl)-2-isopropylamino• -, - encephale isole preparation 477 propanol (H 35/25), pA2-values for -, - food intake 489 p-adrenergic blockade 322t -, - isolated blood vessels 647 5-Methylpyrazole 3-carboxylic acid, anti- -,- noradrenaline lipolytic effect 385f -, -- preBBor response 646 Methyl reserpate methyl ester (Su 9064), --- uptake 207-208, 649 effect on noradrenaline resynthesis 196 -: - oxygen consumption 491, 492f, 493 4-Methyltropolone, effect on dopamine-p- -, - spinal cord reflexes 515 hydroxylase 193 -, - temperature 484, 485 . a-Methyltyramine, formation in liver 628 -, - -, interaction of phenoxybenzamme 3-0-Methyltyramine, formation in brain 495 509-510 a-Methyltyrosine -, formation 189, 191, 626, 627 -, effects on -, histofluorescence 621 -, - behaviour 502 -, loss from -, - brain catecholamines 501-503 -, - peripheral organs (after) 192,625 -, - -, restoration with L-DOPA 502- -, -- guanethidine 645-646 503 -, -- reserpine 644-646 -, - DOPA decarboxylase 191 -, - vesicles after prenylamine 644 -, - formation of -, O-methylation 620 -, -- dopamine 190, 501 -, optical isomers (enantiomorphs) -, -- 5-hydroxytryptamine 190, 19lf -, -, absolute configuration 623 -, -- metaraminol 640 -, -, effect on -, -- noradrenaline 190, 238f, 501, -, -, - blood pressure 623 -, -, - vas deferens 346 627,636-637 -, -, formation 623-624 -, - parkinsonian tremor 851 -,potency 320--321,343t -, - phaeochromocytoma patients -, release by nerve stimulation 205,631- -, - -, blood pressure 916 634, 633t, 649 -, - -, malignant disease 851 -, retention by -, - -, urinary excretion of catechol- -, - adrenergic neurone 188, 621 amines 627,916 -, - granular vesicles 625, 645 -, - tyrosine hydroxylase 190, 501-503 -, - -, electron microscopic evidence 58, -, - tyrosine transaminase 851 63-64, 622 -, metabolism 190, 501, 619, 627-628, 637 -, substitution of noradrenaline 625, 637- -, relief of migraine 850 638 -, toxicity 502 -, uptake a-Methyltyrosine dimethyl ester (H 44/68), -, -, characteristics 622 effect on tyrosine hydroxylase 190 -, -, chromaffin granules 243 Micropinocytosis, of plasma membranes -, -, effect of sympathomimetic amines 596-598 208,649 Microsomes, occurrence in "granule" fraction -, -, membranal 622, 644, 649 539 Subject Index 1041

Microspectrophotometry Monoamine oxidase inhibitors, effect on dop- -, identification of 5-hydroxytryptamine 23 amine P-hydroxylase 505 -, qualitative and quantitative 17 -, - excretion of Microtubules, of -, -- catecholamines 271 - chromaffin cell 601 -, -- phenylethylamine 189 - nerve axon 602--603 -, -- tyramine 189 Migraine, defect in tyramine conjugation -, - 5-hydroxytryptamine in brain 505 850 -, - membrane permeability 190 Minimal current gradient, definition 669 -, - noradrenaline Mitochondria -, -- efflux 741 - in chromaffin cells 27, 68 -, - -, intraneuronal 570 -,MAO in 6 -, -- uptake MJ 1999 (sotalol), see 4-(2-isopropylamino-l• -, -- -, brain 213 hydroxyethyl) methanesulfonanilide -, -- -, extraneuronal 748, 752 MK 485 (DL-a-hydrazino-a-methyl-3,4- -, -- -, nerve particles 213 dihydroxyphenylpropionic acid), inhibi• -, -- -, neuronal membrane 740t, tion of DOPA decarboxylase 862-863 74lf, 742-744, 752 Molluscs, catecholamines in 82t--83t, 91-99 -, -- release 271 Monkey, effects of catecholamines on -, -- synthesis 193-194,235 - behaviour 470,471 -, -- tissue levels 272 - electrocortical activity 471--472 -, - small granular vesicles 58 - temperature 484 -, - sympathetic ganglia 788 Monoamine oxidase (MAO) -, hypertensive response after DOPA 869 -, activity after -, interaction with catecholamine effects on -, - denervation 271, 816 -, - behaviour 505,506 -, - immunosympathectomy 822 -, - spinal cord reflexes 517 -, chemistry 7 -, - temperature 505, 506 -, discovery 5-6, 271 -, mechanism of action 504, 505 -, inhibition, measurement in vivo 620 -, sympathomimetic effects 355 -, isoenzyme(s) of 6-7 -, treatment of parkinsonism 868 -, - MA04 in human brain 858 -, use for identification of adrenergic cells -, occurrence in 47 -, - adrenergic neurones 271 Monoaminergic neurones, discovery of 89 -,- brain Monoamines in pathogenesis of mental dise• -, - -, mitochondria 504 ases 845 -, - -, vascular endothelium 465 Morphine, effect on adrenal medulla 546, -, - glomus cells 24 547t -, - mitochondria 6 Mouse, effects of catecholamines on -, - molluscs 96-97 - behaviour 470 -, - neuroblastoma 917 - temperature 481 -, - nictitating membrane 752 Muscarine -, - phaeochromocytoma 904 -, effect on -, - submaxillary gland 752 -, - adrenal medulla 587 t -,role in -, - rabbit ear artery 768-769 -, - catecholamine -, ganglionic depolarization 705 -, -- metabolism 271-272, 278-279 -, ganglionic hyperpolarization 704 -, -- release by tyramine 277-278 - receptors, effect of p-adrenergic agonists -, -- termination of action 271-274 on 301 -, - indirect effects of amines 351-352 Muscarinic drugs -, - removal of adrenergic agonists from -, effect on receptor region 303 -, - lipolysis 385£ -, substrate(s) -, - noradrenaline release 768 -, -, octopamine 619 -, - response to nerve stimulation 768- -, -, tyramine 619 769 -, -, stereospecificity 7 -, ganglionic depolarization 705-706 Monoamine oxidase inhibitors -, hyperpolarization of nerve cell body -, accumulation of octopamine 629 704--705 -, effect on -, release of catecholamines from adrenal -, - a-aminobutyric acid influx 190 medulla 584 -, - catecholamines Muscular exercise, effect on tyrosine hydro- -, - -, actions of 271, 274 xylase 195 -, - -, brain 504--506 -, - -, circulating 271 NEM, see N -ethylmaleimide -, - -, metabolism 271-272 Neostigmine, effect on -, - dopamine in brain 272, 868 - ganglia 695 66 Hdb. expo PharmakoJ., Vol. XXXIII 1042 Subject Index

Neostigmine, effect on mesenteric artery 767 Nictitating membrane, effect of - nictitating membrane 767 -, - acetylcholine 764 - spleen 767 -, - nicotine 764 Nerve granules, see synaptic (granulated) -, - sympathetic nerve stimulation vesicles -, - -, anticholinesterases 766-767 -, definition 214, 241 -, - -, hemicholinium 765 Nerve growth antiserum -, neuro-muscular distance 729 -, effect on sympathetic ganglia 819-821, Nonshivering thermogenesis, adaptation for 820£,831 408, 417-419, 418f -, penetration across blood-brain barrier Noradnamine, inhibitor of COMT 506 831,835 Noradrenaline [see also catecholamine(s)] Nerve growth factor 11, 818-819, 819£ -, accumulation in brain Neuroblastoma -, -, effect of combined pretreatment with -, catecholamine reserpine and MAO inhibitors 218 -, - metabolism 917 -, -, effect of desmethylimipramine 499 -, - release 920-922 to 500 -, - subcellular distribution 919 -, -, effect of imipramine 499-500 -, - synthesis 917 -, -, effect of MAO inhibitors 505 -, - tissue content 917, 918t, 919 -, appearance during morphogenesis 21 -, - urinary excretion 920-922 -, available pool of 205,217 -, classification 921 -, brain concentration after DOPA 495 -, microscopical observations 919-920 -, -, pretreatment with Ro 4-4602 496 -, occurrence 900,917 -, calorigenic response, role of brown adipose Neuroglia, role in uptake of drugs 464-465 tissue 417-419 Neuromuscular transmission, effect of cate- -, compartment, size of (for tyramine) cholamines on 796-802 338-339 Neurosecretory vesicles in neuropiles of mol- -, disappearance from brain luscs 95-96 -, -, effect of DMI 499 Neuro-sympathomimetic amines 336 -, -, effect of imipramine 499 Nialamide, effect on -, displacement from vesicles by tyramine - electrocortical activity 506 337 - noradrenaline uptake in nerve particles -, distribution 213 -, -, after administration 274-275 Nicotine -, -, in homogenization fractions of adre- -, effect on nergic nerves 217 -, - ganglionic transmission 699-703 -, -, in sympathetic nerves 543f, 544 -, - nictitating membrane 764 -, effect (action) on -, - noradrenaline storage 214,219 -, - behaviour (after) -, indirect action -, - -, interaction of adrenergic anta- -, -, pulmonary artery 356 gonists 507, 508 -, -, spleen 764 -, -- intracerebral injection 473-474, -, release of 512 -, - ATP from adrenal medulla 549t, 551 -, -- intracisternal injection 469-470, -, - catecholamines 511 -, - -, adrenal medulla 549t, 587t -, -- intravenous injection 474-476 -, - -, inferior mesenteric ganglion 124 -, -- intraventricular injection 470- -, - noradrenaline 471,512 -, - -, characteristics 769-771 -, - blood pressure 647-648 -, - -, role of calcium 588t -, - -, intraventricular injection 494, Nicotinic acid, antilipolytic effect 385f 511 Nicotinic drugs -, - dopamine synthesis 194,195£ -, effect on adrenergic -, - electro cortical activity 472-478 -, - nerve cell body 695-696 -, - -, interaction of adrenergic anta- -, - nerve terminals 704 gonists 508 -, release of -, - encephale isole preparation 477 -, - catecholamines from adrenal medulla -, - EPP 801-802 584 -, - food intake 488-491 -, - noradrenaline 767-774,777 -, - -, interaction of adrenergic antago- Nictitating membrane nists 510 -, catecholamine-containing cells, fine- -, - ganglionic membrane potential 788 Btruoturo 52t to 732 -, cholinesterase in 779-780 -, - heart 648 -, decentralization 818f,832-834 -, - heart rate after intraventricular in- -, "degeneration contraction" 735, 737, 817 jection 494 -, denervation 815-817, 818f, 832-834 -, - hemodynamics in man 648 Subject Index 1043

Noradrenaline [see also catecholamine(s)), Noradrenaline [see also catecholamine(s)], effect (action) on 5-hydroxytryptamine metabolism synthesis 823 -, -, conjugation 277 t -, - intestinal acetylcholine output 792 -, -, deamination 271-272 to 796 -, -, effect of -, - isolated blood vessels 647 -, -, - amphetamine 278 -, - metaraminol uptake 208 -, -, - reserpine 210,218,277,278 -, - molluscan heart 98 -, -, - sympathectomy 821-822 -, - nerve stimulation after reserpine pre- -, -, - tyramine 277 treatment 210f -, -, O-methylation 272-274 -, - neuromuscular transmission 798- -, metabolites in urine 276-277 800 -, occurrence in -, - nictitating membrane 346 -, - amphibia 114-115, 137t, 139-141 t -, - noradrenaline synthesis 194, 195£, -, - annelids 81 t, 89-91 234-235 -, - aortic body 23 -, - noradrenaline uptake 207 -, - arthropods -, - oxygen consumption 491 -, - -, crustaceans 83t, 99 -, - shivering 491--4,94 -, - -, insects 84t, 99 -, - skeletal muscle 796-798 -, - birds 117,143-147t -, - spinal cord reflexes -,- bony fishes 113-114, 136t, 138t -, - -, extensor reflexes 515 -, - carotid labyrinth 19 -, - -, flexor reflexes 515-517 -, - cephalocordates 84t, 103 -, - temperature -, - cervico-thoracic paraganglia 23 -, - -, dose-dependence (rat) 481, 482f -, - chromaffin cells 17-31,36-38 -, - -, interaction of adrenergic antago- -, - coelenterates 81 t, 86-87 nists 509,510 -, - cyclostomata 113, 134t -, - -, intracerebral injection 482--4,85 -, - echinoderms 84t, 102 -, - -, intracisternal injection 481 -, - euselachii 113, 135t, 137t -, - -, intravenous injection (chick) -, - flatworms 81 t, 87 484,485 -, - invertebrates 79-109 -, - -, intraventricular injection 481- -,- mammals 485 -, - -, adipose tissue 130, 169t-170t -, - tryptophan transport into pineal gland -, - -, adrenal gland 121-122, 158t 431 -,- -, blood 131 -, - tyrosine hydroxylation 194,234-235 -, - -, blood vessel walls 129-130, 168t -, - vas deferens 346 to 169t -, - water intake 488--4,91 -,- -, brain 117-119,148t-155t,272 -, formation from -, - -, carotid body 23, 130, 169t, 922 -, - erythro-dihydroxyphenylserine 188 -, - -, carotid body tumour 922,923t -, - erythro-m-hydroxyphenylserine 188 -, - -, cerebrospinal fluid 120 -, - "false precursors" 619 -, - -, extra-adrenal chromaffin cells -, - threo-dihydroxyphenylserine 188 22, 123-124 -, ganglionic hyperpolarization 707 -,- -,eye 121,157t -, loading of vesicles 58 -, - -, female sex organs 127, 164t -, loss from -, - -, ganglioneuroma, tissue content -, - brain after 918t -, -- aMDOPA 637 -, - -, gastro-intestinal tract 127-128, -, -- aMMT 637 165t -, -- a-methyltyrosine 636-637 -, - -, glomus jugulare tumour, tissue -, - heart after content 922, 923t -, -- ganglionic blockade 630 -,- -,heart 125, 159-160t, 272 -, -- guanethidine 645-646 -, - -, hypothalamus (parkinsonism) -, -- aMDOPA 636-638 856 -, -- aMDA 636 -, - -, kidney 161 t -, -- metaraminol 636 -, - -, liver 128, 166t -, -- a-methylmetatyramine 636 -,- -,lung 125,161t -, -- aMMT 636 -, - -, male sex organs 126, 162t-164t -, -- a-methyltyrosine 636-637 -, - -, neuroblastoma, tissue content -, -- reserpine 644-646 918t -, - spleen after reserpine 644, 646 -,- -,pancreas 129,168t -, - storage vesicles after prenylamine -, - -, peripheral nerves and ganglia 644 120-121, 156t -, - superior cervical ganglion after decen• -, - -, phaeochromocytoma. tissue con• tralization 630 tent 904,905t -, - vas deferens after aMDOPA 637 -. - -, pineal gland 120 66· 1044 Subject Index

Noradrenaline [see also catecholamine(s)], Noradrenaline [see also ca.techolamine(s)], occurrence in mammals, salivary glands release (by, from, of) sympathetic nerve 129, 166t stimulation, increase by tetraethylam• -, - -, skeletal muscle 131,170t monium 712 -,- -,skin 131 -, - -, muscarinic inhibition 769 -, - -, spinal cord ll9-120,I54t -, - -, newly synthesized amine 196 -, - -, spleen 128-129, 167t, 272 -, - -, role of impulse frequency 693- -, - -, thyroid gland 161 t 694 -, - -, urine 132, 170t -, - -, role of synaptic vesicles 565-582 -, - molluscs -, - tyramine 336 -, - -, cephalopods 83t, 92 -, - a-veratrine and veratrine 713 -, - -, gastropods 82t, 92-95 -, removal from perfusion fluid 202-203 -, - -, pelecypodes 82-83t, 95 -, - as measure of net neuronal uptake -, - protozoans 81 t, 85 728,735 -, - reptiles ll6, 142t -, -, effect of MAO inhibition 740t, 74If -, - ribbon worms 89 -, -, effect of reserpine pretreatment -, - sponges 85 740t,74If -, - sympathetic ganglion 787 -, retention by particulate and supernatant -, - urochordates 84 fraction of heart 645 -, - venoms of insects 99 -, role as -, - vertebrates llO-185 -, - neurotransmitter, discovery 2, 9 -, potency, relative to -, - precursor of adrenaline 2,231 -, - adrenaline 343t -, storage (in) 214-219 -, - isoprenaline 320-321 -, - axoplasm -, quantal release from sympathetic nerves -, - -, failure of release by sympathetic 565-566 nerve stimulation 570-572 -, radioactive, specific activity in tissues -, - -, fluorescence microscopy 571 275 -, -, capacity 216 -, release (by, from, of) -, -, effect of drugs on 218-219 -, - acetylcholine 634 -, -, reserpine-resistant store 218 -, - -, enhancement by atropine 768 -, -, specific stores 200, 205, 214 -, - -, inhibition by muscarinic action -, subcellular localization in sympathetic 768 nerves 543-544 -, - -, mechanisms 778 -, substitution by false transmitters 625- -, - adrenergic nerves 217-218, 544- 626 546 -, - non-stoichiometric 638 -, - -, concentration at adrenoceptors -, - stoichiometric 637 after 752-754 -, supersensitivity to 817, 818f, 832-834 -, - -, effect of cocaine 753 -, synthesis -, - -, inactivation of noradrenaline after -, -, effect of adrenergic false transmitters 753-754 639-642 -, -, combined with release of false trans- -, -, effect of a-methyltyrosine 190, 19If mitters 647-652 -, -, effect of precursors 190 -,- DMPP 634 -, -, feedback control mechanism 187, -, -, effect of 190, 194 -, -, - anticholinesterases 766-767 -, -, induction 193-196 -, -, - decentralization 202 -, -, inhibitors 190-193 -, -, - ganglionic blocking agents 202 -, -, kinetics 196 -, -, - vagal stimulation 781 -, -, localization 189 -, - indirectly acting amines 629, 634- -, -, pathways 186-187 636 -,-,phaeochromocytoma 902,903 -, - isolated nerve particles 200 -, -, rate limiting step 187, 190 -, - lysolecithin 592 -, -, regulation 193-196, 195f -, -, muscarinic inhibition of 706-707 -, transport in sympathetic nerve 602-603 -, - nicotinic drugs 767-774 -, turnover (brain) 468 -, -, rate of, from granules of male sex -, -, effect of MAO inhibition 505 organs 126 -, -, specific 197-202, 205 -, -, role of calcium 581, 781-782 -, -, -, effect of reserpine 210f -, -, role of sodium 782 -, -, tissues 197-198 - -,spontaneous 629,630 -, uptake (by, in) -, - sympathetic nerve stimulation 201- -, - axonal membrane 197 202, 629, 631-634, 633t, 767-774 -, - blood platelets 132 -, - -, amount per stimulus 566-570, -, - brain after intraventricular injection 568t 467-469 -, - -, amount per varicosity 567-570 -, - -, effect of MAO inhibition 466-467 Subject Index 1045

Noradrenaline [see also catecholamine(s)], Normetanephrine, occurrence in brain 469 uptake (by, in) chromaffin granules 242, -, - neuroblastoma 917 253-254 -, urinary excretion 276-277 -, -, correlation to adrenergic innervation Norphenylephrine, potency 343t 816 N orsynephrine, potency 343 t -, -, effect of Nortriptyline, effect on noradrenaline uptake -, -, - chemical sympathectomy 828 and release on nerve particles 213, 218 -, -, - degeneration of adrenergic nerves NSD 1024, see m-hydroxybenzyloxyamine 198-199 NSD 1034, see N-methyl-N(3-hydroxy• -,-, - depletion (bulk uptake) 202 benzyl)-hydrazine -, -, - immunosympathectomy 821 NSD 1039, see N-methyl-N-(2-hydroxyben• -, -, - inhibition of synthesis (bulk up- zyl)-hydrazine take) 202 Nucleoside triphosphatase, in chromaffin -, -, - reserpine (rat iris) 199 granule membrane 559 -, -, - surgical sympathectomy 816 N-wave, in superior cervical ganglion 675f -, -, membranal 644, 649 Nylidrine, interaction with propranolol 299 -,- organs 197-198 to 300 -, uptake in adrenergic nerves 197-214 -, -, effect of "Occupation theory" of drug action 288 -, -, - adrenergic blocking agents 208- Octopamine (OA) 209 -, accumulation after MAO inhibition 629 -, -, - enzyme inhibitors 213 -, effect on -, -, - ganglionic blockers 209 -, - adrenergic transmission 650-651 -, -, - metabolic inhibitors 213-214 -, - noradrenaline synthesis 639-641 -, -, - neuronal blockers 209 -, formation 626 -, -, - psychotropic drugs 209-213 -, indirect actions 346, 648 -, -, - sympathomimetic amines 207- -, loss from heart after 208 -, - guanethidine 645-646 -, -, importance of density of innervation -- phenylethylamine derivatives 636 833 -, - reserpine 645 -, -, parallelism with 5-hydroxytrypt• -, - sympathomimetic amines 350 amine uptake in platelets 205 -, occurrence in -, uptake in adrenergic nerve granules 200 -,- cephalopods 92,189 to 202 -, - heart 189, 629 -, -, effect of -, - kidney 189 -, -, - ADP 204 -, - urine 189, 629 -, -, - AMP 204 -, optical isomers, direct and indirect effects -, -, - ATP 204f, 205 346 -, -, - ATPfMg++ 200,204f -, release by nerve stimulation 205, 631- -, -, - cAMP 204 632,633t -, -, - CTP 204 -, transformation to noradrenaline 189 -, -, - rTP 204 -, uptake by -, -, - Na+ 204 -, - adrenal medullary granules 242 -, -, - oxidative phosphorylation 205 -, - isolated nerve particles 201 -, -, - UTP 204 Oestradiol, effect on -, urinary excretion 276-277 - noradrenaline content of female sex or• -, - after adrenalectomy 275 gans 127 -, - after reserpine 193 - PNMT activity 32 (+ )-Noradrenaline Oestrus cycle, effect on catecholamines in -, inhibition of uptake of (-)-isomer 739 female sex organs 127 -, neuronal uptake 739, 740 Oil immersion technique 274, 728 Noradrenergic transmission, impairment by Oligomycin, effect on reserpine 498 - catecholamine secretion from adrenal Normetanephrine 273t medulla 213 -, effect on - noradrenaline uptake and storage in nerve -, - electro cortical activity 477 particles 213-214, 218 -, - noradrenaline uptake 207 - phosphate uptake in brown adipose tissue -, indirect effect on ileum 350 414-415 -, inhibition of extraneuronal uptake 303, Organ of Zuckerkandl 748 -, catecholamines in 123 -, metabolism -, innervation of 38 -, -, conjugation 277 Ouabain -, -, deamination 276-277 -, antilipolytic effect in fat cells 382, 385f -, N-methylation of 231-232 -, effect on -, occurrence in -, - adrenal medulla 589 1046 Subject Index

Ouabain, effect on amino acid transport Parkinsonism, Parkinson's disease (after) 383 -, association with low blood pressure 855 -, - calcium uptake by heart 398 -, arteriosclerotic, aetiological factors 847 -, - glucose transport 383 -, biochemical considerations 848-858 -, - hyperpolarizing afterpotential 673 -, brain level of 5-hydroxytryptamine 879 -, - Na-K-ATPase 382-383 to 880 -, - nicotinic late hyperpolarization 697 - carbon monoxide poisoning 848 -, - noradrenaline uptake 213 -, degenerative changes in basal ganglia -, - posttetanic hyperpolarization 673 846 Ox, effects of catecholamines on temperature -, dopamine metabolism 854-857 484 -, drug-induced (after) Oxedrine -, - haloperidol 848, 854, 860 -, behaviour after intracisternal injection of -, - phenothiazines 848, 854-855, 860 470,511 -, - reserpine 848 -, lipolysis after 312-313 -, -, response to L-DOPA 861 Oxidative phosphorylation -, effect of catecholamines on skeletal muscle -, brown adipose tissue 798 -, -, "loosening" by FFA 410f,413 -, idiopathic -, -, uncoupling by -, -, aetiological factors 847, 856 -, -, - dinitrophenol 413, 414f -, -, response to L-DOPA 860-861 -, -, - FFA 412-415 - manganese in toxication 847-848 -, -, - FCCP 413-414 - -, response to L-DOPA 861 -, salivary glands, amylase secretion by 424 -, melanin of substantia nigra cells 857 -, uncoupling agents, catecholamine uptake -, models of, in animals 846-847 and release 213-214,219 -, MAO activity in brain 858 Oxotremorine, ganglionic -, postencephalitic - depolarization 706 -, -, aetiological factors 847 - hyperpolarization 704 -, -, response to L-DOPA 861 Oxygen uptake -, treatment with -, brown adipose tissue 411-413 -,- amantadine 869-870 -, effect of catecholamines 437-438, 491 -, - anticholinergic drugs 870 Oxytocin, effect on noradrenaline uptake -, - L-DOPA 4,188,860-869 214 -, - metatyrosine 879 Pempidine, effect on noradrenaline release pA2-values 775 -, erroneous estimates of 307-317,321 Pentachlorophenol, effect on noradrenaline -, estimation of, for classification of uptake and release from nerve particles -, - agonists 290-291 214 -, - -, indirect actions of 298 Pericardial organs of crustaceans, innervation -,- receptors 290-291 100-102 -, - sub-types of fJ-adrenoceptors 321- Phaeochromoblastoma (see also Phaeochro- 325,322t mocytoma) 900 Pancreas Phaeochromocytoma -, adrenergic innervation of 129 -, catecholamine(s) -, catecholamines in 129, 168t -, - plasma levesl 911-912 -, cholinesterase in 780 -, - release 911-917 -, exocrine -, - -, effect of tyramine 914 -, -, movement of granules 596-597 -, - synthesis 902-903 -, -, transport of proteins 598 -, - -, regulation of 235 -, fine structure of catecholamine-contain- -, - tissue content 22,904, 905t, 906 ing cells 52 t -, -, turnover rate 903-904 Paradoxical sleep 472,474 -, -, urinary excretion 902,912-913 Paraganglia, see chromaffin cells, extra-adre• -, -, -, after insulin 913 nal -, -, -, after a-methyltyrosine 627, 916 Paragangliomas 900 -, diagnosis Parasympathetic ganglia, adrenergic nerve -, -, angiography 913 terminals in 787 -, -, provocative tests 914-915 Parathyroid hormone, effect on kidney ade• -, -, urinary excretion of catecholamines nyl cyclase 433 and metabolites 912 Paredrine, effect on behaviour after intra• -, -, venous sampling technique 911-912 cisternal injection 470, 511 -, incidence 900-901 Pargyline, effect on -, lack of innervation 911,913 - noradrenaline uptake in nerve particles -, location 902 213 -, malignancy - sympathetic ganglia 788 -, -, biochemical aspects of 912-913 Subject Index 1047

Phaeochromocytoma, malignancy, percentage Phenylethanolamine-N -methyl transferase 913 (PNMT), discovery 2, 231 -, N-methylmetanephrine in 232 -, inhibitors of 232 Phenformin, antilipolytic effect 385f -, localization in cytosol 31 Pheniprazine, effect on noradrenaline uptake -, occurrence in chromaffin cells of and release 213 -, - mammals 231 Phenothiazine derivatives, effect on noradren- -, - reptiles 116 aline uptake 208 -, substrates 231, 619 Phenoxybenzamine Phenylethylamine -, adrenoceptor blockade 299,304, 305t -, AMP release from adrenal medulla 549t, -, effect on 551 -, - COMT activity 278 -, behaviour after intraventricular injection -, - insulin secretion 421 512 -, - O-methylation 278, 749, 753 -, catecholamine release from adrenal -, - neuromuscular junction 800 medulla 549t, 551, 590 -, - noradrenaline -, -, role of Ca/Mg 587t -, -- overflow from spleen 208, 211 - fate in tissues 572 -, -- synthesis 193 - occurrence in urine 189 -,- - uptake 208--209,748,753 - supersensitivity to 833 -, -- -, extraneuronal 278, 303 Phenylisopropylhydrazine -, - non-adrenergic receptors 316 -, amphetamine-like stimulation 505 -, - release of -, inhibition of MAO 505 -, -- chromogranin A 576 Phenylpropanolamine -, -- dopamine-p-hydroxylase 576 -, cocaine-resistant accumulation 351 -, indirect effect on heart 353 -, effect on Phentolamine -, - adrenal medulla 587 t -, adrenoceptor blockade 307, 308f, 309 -, - behaviour 511 -, -, neuromuscular junction 800 -, indirect effect 351 -, -, time for equilibrium 317 Phospholipids (in) -, effect on -, chromaffin granules after lysis 558 -, - 5-hydroxytryptamine receptors 316 -, release from adrenal medulla 558 -, - insulin secretion 421-423 -, turnover in adrenal medulla 594 -, - lipolysis 316-317,386-387,423 Phosphoenolpyruvate carboxykinase, induc- -, - muscle glycogenolysis 423 tion in liver 375-376, 378f -, - noradrenaline uptake 208-209 Phosphorylase, see glycogen phosphorylase -, - smooth muscle preparations 314,348 Physalaemin, ganglionic action 710 -, indirect effect on heart 353 Physostigmine, effect on -, pA 2-values 326-327t, 328--329 - nictitating membrane 766-767 Phenylephrine - noradrenaline uptake and release· 213 -, effect on - spleen 767 -, - behaviour after Pilocarpine -, -- intracisternal injection 511 -, ganglionic depolarization 706 -, -- intraventricular injection 470, -, stimulation of adrenal medulla 587t 512 Pilomotor muscles -, - muscarinic receptors 301 -, contraction by -, optical isomers, direct and indirect effects -, - acetylcholine 764 344,346 -, - -, block by hexamethonium 774 -, potency -, - nicotine 764 -, - a-adrenoceptors 326t--327t, 328-- -, innervation of 763 329,343t,344 Pineal gland -, - p-adrenoceptors 321-325,322t, -, acetylcholinesterase in 781 343t -, catecholamines in 120 -, selective agonist for a-adrenoceptors -, fine structure of catecholamine-containing 298--299 cells 52-53t Phenylethanolamine, cocaine-resistant accu• -, monoamines in 58 mulation 351 -, regulation of metabolism 428-432 Phenylethanolamine-N -methyl transferase "Pink spot", see also 3,4-dimethoxyphenyl• (PNMT) ethylamine, identity of 850, 858 - activity, effect of Placenta, noradrenaline uptake by 199 -- ACTH 32 Positive afterpotential, see hyperpolarizing -- adrenocorticosteroids 32, 124, 232, afterpotential 903 Postganglionic sympathetic denervation, see -- gonadotrophins 32 sympathectomy -- sexual hormones 32 Postspike positivity, see hyperpolarizing after• -, characteristics 231,562 potential 1048 Subject Index

Posttetanic hyperpolarization (in) Propranolol, effect on lipolysis 314, 386- - adrenergic C-fibres 686 387 - adrenergic nerve cell body 686 -, - non-adrenergic receptors 316 - sympathetic ganglionic cells 673 -, - skeletal muscle 797 -, role of sodium-pump 686 -, optical isomers Potassium -, -, effect on insulin secretion after tol- -, action on adrenergic nerve terminals butamide 421 775-776 -, pA 2 -values 322t, 324 -, decentralization supersensitivity to 833 Propylhexedrine, affinity for noradrenaline -, metabolism in liver 376-377 uptake site 207-208 -, release of Prostaglandins (E-series) -, - catecholamines and ATP from adrenal -, effect on medulla 549t, 551, 587t -, - adrenergic nerve terminals 711 -, - noradrenaline 588t, 775, 781 -, - ganglia 711 -, role in -, - lipolysis 385f -, - amylase secretion 424 -, - noradrenaline uptake 214 -, - ganglionic AP 669 -, release during nerve stimulation 618, -, - nicotinic late hyperpolarization 696 711 to 697 Prostigmine, effect on noradrenaline uptake -, - posttetanic hyperpolarization 691 and release 213 Potentiation, see supersensitivity Protein kinase, cAMP-dependent, in liver Practolol, pA2-values as p-adrenergic anta• 365,369 gonist 322t, 324-325 Proteins in Preganglionic sympathetic denervation, see - chromaffin granules 539 decentralization -- after lysis 558-559 Pregnancy, effect on catecholamines in female -- after stimulation 551-559 sex organs 127 - synaptic vesicles Prenylamine, effect on - -, release by sympathetic nerve stimula- - catecholamine release from tion 574-578 -- adrenal medulla 587 t Protocatechulaldehyde, see dihydroxy- -- chromaffin granules 258-259 phenylformaldehyde - noradrenaline Protozoans, catecholamines in 81 t, 85 -- uptake and storage in nerve particles -, incorporation of amino acids 85 208,218 Pulmonary artery (rabbit) -- synthesis 193 -, neuromuscular distance 730,731 Probenecid -, noradrenaline release per varicositY -, diagnostic test for parkinsonism 860 567,568t -, effect on homovanillic acid transport -, response to sympathetic nerve stimulation 846,859 after DMPP 773 Procaine, effect on ganglia 712 Puromycin, effect on Pronethalol - PNMT activity 32 -, effect on - salivary gland DNA synthesis 426 -, - cAMP formation 314 Purple gland of N ucella la pilIus 17 -, - lipolysis in white adipose tissue 386 P-wave (sympathetic ganglia) 678-683, to 387 675f -, - non-adrenergic receptors 316 - after blockade of nicotinic receptors 681 -, - skeletal muscle 797 -, effect on postspike positivity 681 -, intrinsic sympathomimetic activity 314 -, involvement of adrenaline 682 -, pA2-values 322t, 324-325 Pyridoxal-5' -phosphate -, specificity of p-adrenoceptor blockade -, chemical reaction with catecholamines 286 188,867 -, time required for -, coenzyme for L-DOPA decarboxylase -- equilibrium 317 188,867 Propionaldehyde, indirect effects 353 -, effect on Propionylcholine, ganglionic depolarization -, - formation of dihydroxyphenylpyruvic 706 acid 867 Propranolol -, - therapeutic action of L-DOPA 867- -, effect on 868 -, - a-adrenoceptors 314-315 -, formation of Schiff's bases 867 -, - p-adrenoceptors 306, 306f, 307, 310 Pyrogallol, effect on -, - -, specificity of blockade 286 - COMT 273, 306, 506 -, - Clio uptake by sarcoplasmic reticulum - catecholamines in brain 507 398 - viability of isolated organs 306 -, - calorigenic action of noradrenaline Pyruvate carboxylase, inhibition by calcium 412 372 Subject Index 1049

Quantal release of Reserpine, effect on noradrenaline release - neurotransmitter from 566, 570-571 -- ganglia 675 -, -- storage 218, 260f, 277 -- motor neuron 570,590-591,802 -, -- synthesis 193,236, 238f - noradrenaline from sympathetic nerves -, -- uptake 204f, 209-211, 247f 565-566,580 -, - spinal cord reflexes 517 -, - synaptic vesicles 56-58,574 Rabbit, effect of catecholamines on -, exacerbation of parkinsonism 870 - electrocortical activity 472 -, persistence of amines after 218, 635 - temperature 482-483 -, response to Rat, effect of catecholamines on -, - sympathetic nerve stimulation 21Of, - behaviour 470--471, 473 217,498,652 - temperature 481-482 -, - -, restoration 210f, 570-571, 631 Rauwolfia alkaloids 5 -, - tyramine 297-298, 340-341 Receptor-agonist complex 288 -, - -, restoration 338, 631, 634-635 Receptor-antagonist complex 290 -, sedation, reversal by DOPA 498 Reproductive organs -, subsensitivity after 340, 739 -, catecholaminesin 126-127,162t-I64t -, supersensitivity after 739, 742, 833 -, adrenergic innervation of 126-127 -, sympathomimetic activity 277 Reptiles Respiration, effect of intraventricular adren- -, catecholamines in 116, 142t aline 471 -, chromaffin cells in 20 Ribbon worms, catecholamines in 88-89 Reserpine Ribonucleic acid (RNA) -, abolition of indirect effects of amines -, occurrence in "granule" fraction 539 297-298,340--341 -, salivary gland, effect of isoprenaline 426 -, effect on Ro 4-1284, effect on noradrenaline resyn• -, - adrenergic false transmitters 211, thesis 196 644-646 Ro 4-4602, see N-(DL-seryl)-Nl-(2,3,4- -, - adrenal medulla 30-31, 557-558 hydroxylbenzyl)-hydrazine -, - -, ATP 547t, 548t, 550 Rotenone, effect on -, - -, catecholamines 547t, 548t, 550 - lipolysis 385f -, - -, role of calcium 587t - noradrenaline-stimulated respiration -, - behaviour 497-498 413,414f -, - -, action of DID 500-501 - noradrenaline uptake on nerve particles -, - catecholamine(s) 213-214 -, - -, adrenal medulla 244, 261 Rubidium, effect on posttetanic hyperpolari• -,--, brain 497-500 zation 691 -, - -, carotid body 70 -, - -, chromaffin cells 16, 124 Salbutamol, selective p-adrenergic agonist -, - -, chromaffin granules 243-244, 324 258-259 Salivary gland, of -, - -, discovery 5, 244 - mammals -, -- metabolism 277 - -, adrenergic innervation 129 -, -,- -, skin 25 - -, catecholamines in 129, 166t -, - chromaffin cells 16, 124 - -, "degeneration contraction" 817 -, - -, endoplasmic reticulum 28 - -, enlargement after -, - -, granules 33-34 - -, - isoprenaline 423, 425-426 -, - -, plasma membrane 33-34 - -, - theophylline 426 -, - -, ribosomes 28 - -, sympathetic denervation -, - -, transport ATPase 245 - -, -, choline acetyltransferase 765 -, - "degeneration contraction" 817 - -, -, noradrenaline 815 -, - dopamine levels - octopus -, - -, molluscs 96 - -, catecholamines in 92, 104, 189 -, - -, reptiles 116 - -, octopamine in 92, 189 -, - dopamine-p-hydroxylase 193, 261, Salsolinol, role in alcohol addiction 864 557-558 Sarcoma tissue, nerve growth factor in 818 -, - excitability of Actinia equina 87 to 819 -, - histofluorescence 130, 571 Sarcoplasmic reticulum, calcium uptake and -, - 6-hydroxydopamine-induced sym- release 397-398 pathectomy 827 Sarin, effect on spleen 767 -, - 5-hydroxytryptamine (brain) 5, 497 Schizophrenia, "pink spot" in 850 to 498 Schwann cell -, - noradrenaline -, membrane fusion with chromaffin cell -, - -, intraneuronal 570 35-36 -, -- metabolism 210, 218, 278 -, sympathetic ganglia 71 1050 Subject Index

Seasonal variations of catecholamines in Spleen, noradrenaline overflow, effect of drugs - amphibia 115 211-213,775-778,777f - mammals -, response to - -, adrenal gland 122 -, - acetylcholine 764, 774-775 - -, brain 118 -, - nerve stimulation 767, 774-775 Second messenger (see also adenosine 3',5'• -, - nicotinic drugs 764,775-777 monophosphate)' concept 363,398 Splenic nerve Serine dehydratase, induction in liver 375, -, cholinergic fibres in 762 378f -, distribution of vesicles in 214-215, Serotonin, see 5-hydroxytryptamine 215£,543f N-(DL-Seryl)-Nl-(2,3,4-hydroxybenzyl)• -, release of acetylcholine after stimulation hydrazine (Ro 4-4602), inhibition of 575-576 DOPA decarboxylase 496-497, 862- Sponges, catecholamines in 85 863 Stereoisomers of adrenergic agonists, compe- Sheep, effects of catecholamines on tempera• titive antagonism between 302 ture 483-484 Stimulus-secretion coupling Short adrenergic neurones, innervation of -, adrenergic nerve terminals reproductive organs 126-127, 815 -, -, effect of bretylium 776 Shy-Drager syndrome 855 -, hypothesis of mechanism 256-257 Skeletal muscle (see also neuromuscular -, role of cell membrane 583-598, 583 f transmission) Storage vesicle, see chromaffin granule, -, catecholamines in 131,170t synaptic (granular) vesicles -, effects of catecholamines on 796-798 "Stress", effect on catecholamines in -, fatigue of 800 - adrenal gland 121 -, twitch tension 796-798 - brain 119 Skin, mammalian, catecholamines in 131 Strontium, effect on ganglionic AP 671 Slow synaptic potentials 677---084 Submaxillary gland Sodium -, ca.techolamines after immunosympathec• - flux in frog skin, effect of drugs 434 tomy 821 -, role in -, nerve growth factor in 819 -, - catecholamine release 589 -, noradrenaline after surgical sympathec- -, - ganglionic potentials 669-670,691, tomy 816 695-697 Subsensitivity (post junctional), after reser• Sotalol (MJ 1999) see 4-(2-isopropylamino-l- pine 739 hydroxylethyl)-methanesulfonanilide Substantia nigra, formation of L-DOPA in 8 Soterenol, selective p-adrenergic agonist 324 Substitute transmitter, see adrenergic false "Spare receptor" systems 288-289 transmitters Spermine oxidase Sucrose-gap technique 663 -, biochemistry 8 Sulphate conjugase in neuroblastoma 917 -, occurrence in ruminant plasma 7 Supersensitivity (to) Spinal cord - acetylcholine, after decentralization -, catecholamines in 119-120,I54t 737,833 - reflexes, effect of catecholamines on 514 - catecholamines (after) to 518 - -, cocaine-like 727,733,737-739 Splanchnic nerve - -, -, stereospecificity 746 -, activity after sympathectomy 834 - -, decentralization-type, see post- - stimulation, effect on junctional -- adrenal medulla 546-551,548t- - -, denervation-type, see prejunctional 549t - -, inhibition of -- -, release of chromogranins 554 t, - -, - COMT 750-752 557 - -, - MAO 742-744 -- -, release of dopamine-p-hydroxylase -- nerve stimulation 739 554t,557 - -, prejunctional type 733-739,733f Spleen - -, postjunctional type 340, 726, 733f, -, acetylcholinesterase in 778 733-734,737-739 -, adrenergic innervation 129 - -, -, stereospecificity 746-747 -, catecholamines in 128-129, 167t -- reserpine 340,739,742 -, catecholamine-containing cells, fine struc- - -, time course of development 727, ture 53t 733f,734 -, chromaffin cells in 576 -, definition 754 -, noradrenaline - a-hydroxytryptamine 737 -, - content after sympathectomy Supra-chiasmatic nucleus, types of vesicles in -, - -, chemical 827-828 64 -, - -, immunological 821 Suprarenal bodies -, - -, surgical 817 -, catecholamines in 18 Subject Index 1051

Suprarenal bodies, innervation of 38 Sympathetic ganglia (see also adrenergic Supraorbital smooth muscle, "degeneration nerve cell body), prevertebral, effect of contraction" 817 amino acids 710-711 Sympathectomy (sympathetic denervation, -, -, - atropine 684-685,705-706 see also immunosympathectomy) 813- -, -, - chlorisondamine 684 844 -, -, - cholinesterase inhibitors 685, -, chemical 823-832 695,705 -, -, definition 814 -, -, - hexamethonium 684-685, 695, -, -, effect on behaviour 829 697 -, -, limitations of 830-831, 835 -, -, - 5-hydroxytryptamine 709 -, -, regeneration of nerve fibres after -, -, - local anaesthetics 712 828,832 -, -, - muscarinic drugs 684-685, 704 -, compensatory mechanisms 832-834 to 705 -, elimination of indirect actions of amines -, -, - nicotinic drugs 699-703 297-298 -, -, - reserpine 791 -, role in studies of -, -, - veratrine 713 -, - enzyme localization 816, 822, 826, -, -, post-activation phenomena 685- 830 687 -, - noradrenaline "Sympathetic myoneural junction" 284 -, -- inactivation 815-816, 830, 835 Sympathetic nerves (see also adrenergic neu• -, -- localization 47,56, 59f, 815, 830, rone) 835 -, catecholamine-containing structures -, - sympathetic nervous system 813, 53t 830,835 -, cholinergic fibres in 762-763 -, surgical Sympathetic nerve stimulation (electrical) -, -, definition 814 -, effect on -, -, effect on -, - brown adipose tissue 409 -, -, - behaviour 813 -, - liver glycogen 371 -, -, - choline acetylase 765 -, - noradrenaline synthesis 193-194, -, -, - noradrenaline content of organs 753 25,814-817 -, - number of synaptic vesicles 604 -, -, - pineal gland metabolism 429,431 t -, - pilomotor muscles 764 Sympathetic ganglia (see also adrenergic -, - pineal gland metabolism 428, 432 nerve cell body) -, - small granular vesicles 56 -, adrenergic nerve terminals in 688, 787 -, - spleen 764 -, axo-dendritic contacts 71 -, - tyrosine hydroxylase 194 -, axo-somatic contacts 71 -, failure to release -, B-cells 688 -, - axoplasmic noradrenaline 570-572 -, catecholamine-containing cells in 52t, -, - DOPA decarboxylase 578 70, 784-787 -, - tyrosine hydroxylase 578 -, C-cells 688 -, release of -, chromaffin cells in 21, 22, 39, 124, 786- -, - chromogranin A 574,588t 787 -, - dopamine p-hydroxylase 574-578, -, convergence of input 688 575f,588t -, divergence of impulses 688 -, - noradrenaline (after) -, electron microscopy of 67-71,69f -, - -, amount per stimulus 566-570, -, innervation 60, 688, 787 568t -, integrative activity 687-688 -, -- adrenergic neurone blocking -, paravertebral agents 774-778 -, -, nerve growth antiserum 819-821 -, -- anticholinesterases 766-767 -, -, removal of 813-816 -, -- DMPP 772-774 -, phospholipid turnover 594 -, -- MAO inhibitors 570 -, presence in postganglionic nerve trunk -, -- metabolites 278 830 -, -- reserpine 570 -, prevertebral -, - -, role of calcium 588t, 781 -, -, nerve growth antiserum 819-820, -, - proteins 574-578 831 -, - vesicular components 576 -, -, removal 813-814, 817 -, response to, after -, release of catecholamines in 791-792 -, - acetylcholine 764-765 -, transmission -, - anticholinesterases 766-767 -, -, effect of -, - botulinum toxin 766 -, -, - a-adrenoceptor agonists 707- -, - guanethidine 781 708, 788-792 -, - hemicholinium 765 -, -, - adrenergic neurone blocking -, - 6-hydroxydopamine 828 agents 712-713, 791 -, - immunosympathectomy 821 1052 Subject Index

SyInpathWn 1-2 Synaptic (granular) vesicles (see also chrom• Sympathomimetic amines (see also adre- affin granules), small dense-cored, origin nergic agonists) and fate 603-605 -, affinity to -, stability 216 -,- adrenoceptors 285,342-347 -, subcellular dynamics 602-{j05, 603f -, - membranal uptake 348-351 -,transport 602-{i03 -, classification 336-362 Synaptic inhibition in molluscan neurons 97 -, -, experimental methods 339-341 to 98 -, -, influence of morphology 347-348 Synaptic vesicles -, directly acting 341-352 - in cholinergic nerve endings 18, 19, 36, -, -, decentralization supersensitivity 340 37 -, -, definition 336 -, non granulated 34 -, -, denervation supersensitivity 340 Synaptosomes, noradrenaline in 543 -, -, potentiation by cocaine 339-340 Synephrine -, effects (on) -, effect on muscarinic receptors 301 -, - dopamine-p-hydroxylase 192 -, optical isomers, effect on vas deferens -, - 5-hydroxytryptamine receptors 341 346 -, -, structure-activity relationships 344 -,potency 343t -, - uptake of -, -- a-methylnoradrenaline 208, 349 Testosterone, effect on -, -- noradrenaline 207-208,349 - adenyl cyclase (liver) 369 -, indirectly acting - catecholamines in -, -, aliphatic amines 352-353 -- seminal vesicles 126 -, -, characteristics 297, 341-352 -- vasa deferentia 126 -, -, definition 336-337 - PNMT activity 32 -, -, effect on Tetracaine, effect on -, -, - adrenal medulla 590 - antidromic firing 693 -, -, - noradrenaline - ganglia 712 -, -, -- metabolites 278 - noradrenaline -, -, -- re-uptake 208 -- uptake 212 -, -, -- storage 219 -- release 586, 589, 693 -, -, formation of false transmitters 338, Tetraethylammonium (TEA), effect on 625-629 -- ganglionic electrical activity 711-712 -, -, potentiation by MAO inhibitors 752 - noradrenaline release 712 -, tachyphylaxis 338 Tetraethylpyrophosphate, effect on nictitat• ynaptic (granular) vesicles (see also chro• ing membrane 767 maffin granules) Tetramethylammonium (TMA) -, adrenergic nerve cell body 67-68 -, depolarization of adrenergic nerve cell -, attachment to cell membrane 590-592, body 695-{j96 577f -, nicotinic block of ganglionic transmission -, Brownian motion 583-584, 602 701 -, cytology 214--216, 543f Tetrahydropapaveroline -, dopamine-p-hydroxylase 580, 603 -, formation from dopamine 864 -, electron microscopy 54-60, 55f, 57f, -, occurrence in liver 864 59f -, role in alcohol addiction 864 -, "heavy" noradrenergic 543 Tetrodotoxin (TTX), effect on -, large dense-cored - antidromic firing (adrenergic neuron) -, -, conversion to small vesicles 603- 693,712 604 - EJP 566 -, -, distribution 543-544, 569 - ganglionic potentials 671, 696, 712 -, -, exocytosis, fate after 578-580 - noradrenaline release 693,777-778 -, -, internal matrix 63 - stimulus-secretion coupling 777-778 -, -, origin and fate 603-605 Thallium, effect on posttetanic hyperpolariza- -, "light" noradrenergic 543 tion 691 -, loading with monoamines 58, 60, 352 Theophylline -, noradrenaline content 216, 566 -, antilipolytic effect 385f -, release of -, effect on -, - noradrenaline 566-570 -, - adenyl cyclase of toad bladder 433- -, - proteins 574-578 434 -, reserpine-resistant 64 -, - adrenaline response on neuromuscular -, re-use after exocytosis 604-605 transmission 402 -, role in amine release 565-582 -, - adrenal medulla 589 -, small dense-cored -, - amino acid incorporation 390 -, -, distr'bution 543-544, 569 -, - amylase secretion 423--424 -, -, exocytosis, fate after 580-582 -, - brain cAMP 427 Subject Index 1053

Theophylline, effect on brown adipose tissue Tyramine, effect on (after) nictitating mem- metabolism 409, 412 brane 348 -, - insulin secretion 419-423,420f -, - noradrenaline -, - lipid metabolism of liver 374 -, -- release by nerve stimulation 643t -, - melanophores 434 -, -- synthesis 640 -, - phosphodiesterase (white adipose tis- -, -- uptake 207-208, 338 sue) 379 -, - rabbit ear artery 348 -, induction of tyrosine transaminase 375 -, - reserpine 336 -, inotropic response, effect of acetylcholine -, - umbilical artery 339 399 -, - vas deferens 339 Thiol containing compounds, antilipolytic - metabolism effect 385f - -, conjugation in man 850 Thymoxamine, a-adrenergic a.ntagonist - -, conversion to 322t,325 - -, - dopamine 189 Thyroid gland, catecholamines in 126, 161 t - -, - noradrenaline 189 Thyroid stimulating hormone, effect on ade- - -, - octopamine 189, 338, 619, 626 nyl cyclase 379 - -, deamination 7, 337, 619 Thyroid tumour -, mode of action 277,337-339 -, catecholamines in 901 -, occurrence in -, 5-hydroxytryptamine in 901 -, - cephalopods 92 Thyroxine, effect on -,- CNS 189 - cardiac adenyl cyclase activity 392 -, - urine 189, 921 - dopamine-p-hydroxylase 193 -, potentiation of histamine 341 - tyrosine hydroxylase 195 -, release of TM 6, effect on noradrenaline uptake 209 -, - catecholamines TM 10, see choline 2:6-xylylether -, - -, adrenal medulla 241, 914 Tolazoline, effect on a-adrenoceptors 353 -,- -,phaeochromocytoma 914 Tolbutamide -, - -, role of CafMg 587t -, antilipolytic effect 385f -, - histamine 341 -, effect on insulin secretion 421 -, - noradrenaline 277-278, 337-339 Transplantation of Kidney, "degeneration -, - -, role of calcium 588t, 590 contraction" of vessels after 817-818 -, - -, time course 773 Transverse tubules (T-tubules) in cardiac - uptake by muscle 396 -- adrenal medullary granules 242- Tranylcypromine 243,245 -, inhibition of PNMT activity 232 -- adrenergic nerves 205, 337 -, release of noradrenaline in brain 505 -, urinary excretion (neuroblastoma) 921 Tricyclic antidepressants, antilipolytic effect Tyrosinase 385f -, occurrence in melanin cells 8 2,3,4-Trihydroxyacetophenone, inhibitor 0 -, role in catecholamine autoxidation 8 COMT 506 Tyrosine 3f,849f Trihydroxyindole method 111-112 -, decarboxylation 3,187,188 Trimetoquinol, selective p-adrenergic agonist -, formation 187 324 -, hydroxylation 31, 187, 850 Tropolone, inhibitor of Tyrosine hydroxylase - COMT 323, 506 -, characteristics 187 - dopamine-p-hydroxylase 506 -, effect of Tropolone-4-acetamide, inhibitor of COMT -, - chemical sympathectomy 826 304,507 -, - catecholamines 234-236, 640 Tuamine, effect on noradrenaline uptake 208 -, - -, neuroblastoma 917 Tuaminoheptane, effects on behaviour 511 -, - -, phaeochromocytoma 904, 916 Tubero-infundibular neurone system, role in -, - metaraminol 640--641 gonadotrophin secretion 866 -, - octopamine 640 d-Tubocurarine, effect on -, - surgical sympathectomy 816 - antidromic ganglionic A.P 671 -, inhibition 190-191, 235, 237, 501-502 - fast EPSP in sympathetic ganglia 676 -, Km value 196 - nicotinic AP at adrenergic nerve terminals -, lack of release by nerve stimulation 578 704 -, localization 187, 189 Tumours, dopamine-secreting, urinary ex- -, occurrence in cretion of metabolites 874 -, - chromaffin cells 8, 562 Tyramine -, - -, neuroblastoma 917 -, effect on (after) -, - -, phaeochromocytoma 904, 916 -, - adrenergic tranSmission 643t -, role in parkinsonism 848-851 -, - 6-hydroxydopamine 828 -, substrates 619, 627 -, - imidazole-N-methyl transferase 341 -, transsynaptic induction 235,600, 834 1054 Subject Index

Tyrosine transaminase Uptake, neuronal, saturation, slopes of dose- -, activation by response curves 744-746 -, - catecholamines 876 -, -, stereospecificity 200--201, 746 -,- DOPA 876 -, non-neuronal 303 -, induction in liver 375-376, 378f -, vesicular 337,352,622,740--744 -, role in catecholamine synthesis 851 -, -, affinity of sympathomimetic amines 352 U-0521, see 3',4'-dihydroxy-2-methyl• -, -, definition 337 propiophenone -, -, stereospecificity 740 Uncoupling of oxidative phosphorylation in Uptakel , see uptake, membranal and uptake, brown adipose tissue mitochondria 412 neuronal to 415 Uptakes (see also uptake, extraneuronal) Urine, catecholamines in 132, 170t 204,278,748 Urochordates, catecholamines in 84, 103 Urosympathin, composition of 132 Vanillic acid, urinary excretion Uterine artery, release of noradrenaline per -, neuroblastoma 921 varicosity 567,568t -, phaeochromocytoma 913 Uterus, catecholamines after immunosym• Varicosities of adrenergic nerves pathectomy 821 -, noradrenaline concentration 216 Ultradian rhythm of catecholamines in rat -, types of vesicles in 544 brain 119 Vas deferens Ultramorphological studies, see electron -, autonomic nerves 779f microscopy -, catecholamine-storing cells, fine struc- Uptake amines ture 53t -, extraneuronal 274, 278-279, 747-753 -, neuro-muscular distance 729 -, -, differences to neuronal uptake 748 -, noradrenaline (after) -, -, effect of COMT inhibition 748-752 -, - chemical denervation 827 -, -, effect of MAO inhibition 748, 752 -, - immunosympathectomy 821 -, -, inhibitors of 748-749 -, - surgical denervation 827 -, -, organ differences 748 -,- uptake 218,570 -, -, species differences 748 -, varicosity 577f -, membranal (see also neuronal uptake) Vasopressin, effect on 197-198,337,348-351,622 - adenyl cyclase (toad bladder) 433--434 -, -, affinity of sympathomimetic amines - blood pressure after intraventricular in- 348-351 jection 494 - kidney adenyl cyclases 433 -, -, definition 337 - noradrenaline uptake 214 - -, methods for study 348-349, 622, Veratrum alkaloids, effects on adrenergic 728 neurone 713 - -, stereospecificity 349-351 Vertebrates -, neuronal 274,278-279,733-747 -, catecholamines in 110--185 -, -, effect of cocaine 727,737-739 -, chromaffin cells in 17-22 -, -, effect of denervation Vinblastine, effect on adrenal medulla 601 -, -, -, chemical denervation 737 Viscero-visceral reflex, after decentralization -, -, -, surgical denervation 727, 733- 688 736 Vitamin K5, antilipolytic effect 385f -, -, effect of MAO inhibition 740t, 74lf, VMA, ("vanillylmandelic acid"), see 3- 742-744 methoxy-4-hydroxymandelic acid -, -, effect of nerve stimulation 739 Vomiting, after catecholamines 471,475 -, -, effect of reserpine pretreatment 740t, 74lf,742-743 Water intake -, -, effect of sympathomimetic amines -, effects of catecholamines 488--491 739 -, relation to thermoregulation 490--491 -, -, influence on relative potencies of White adipose tissue, isolated cells, prepara• directly acting amines 303-304, 305t tion 379 -, -, quantitative considerations 735, 736 -, -, saturation 203, 307-313, 744-747 Xylocholine, see choline 2: 6-xylyl ether