My Index Expurgatorius Would Run Much As Follows

Total Page:16

File Type:pdf, Size:1020Kb

My Index Expurgatorius Would Run Much As Follows their union, so must the united Pharmacopaeias set an example The number of alkaloids and other active principles of plants of self-abnegation. should be increased. Aconitia, of which a certain mode of Thus, as a melancholy indispensable in our new pharmaceutical preparation has been published, should not have been omitted reform bill, I beg to present a list of rotten boroughs for dis- from the last London Pharmacopoeia. The principles of conium, franchisement-a catalogue of drugs drawn from the materia hyoscyamus, tobacco, lobelia, and other active drugs, might be medica of the three Pharmacopoeias whose constituencies, or retained in greater safety if combined with an acid, such as the doctors who prescribe them, have become so extremely sulphuric, which renders them very soluble in water. For limited that it seems scarcely necessary to retain them any convenience of prescribing, and the avoidance of mistakes in longer. dispensing such powerful poisons, I would recommend that Index run as standard of one certain of dose should be My Expurgatorius would much follows :- , solutions strength Absinthium, acetum, acidum aceticum (omit eight of these, ordered in the British Pharmacopoeia. Such solutions would and leave only a strong acid of 85 per cent., and a dilute acid be uniform in strength, and more to be depended on for cer- of 5 per cent.), allium, althsea, anethum, angelica, anthemidis tainty and safety of effect than any tincture, juice, infusion, or oleum, aurantii fructus, balsamum Canadense, barytas carb. et extract of the plant, the amount of whose active principle of sulph., calamina (replace by pure carb. zinc), calamus aroma- course varies much. Mistakes would be next to impossible if ticus, canna, cannabis, carota, cassiae cortex et oleum, casto- all the solutions of the Pharmacopoeia were so diluted that the reum, centaurium, chiretta, cinchona cinerea, cocculus, cornu ordinary dose for an adult man should be just one drachm, and et c. ustum (replace by pure phosph. lime), cyminum, dul- in no case more or less. This is already the case with the liquor camara, euphorbium, gossypium, hemidesmus, inula, lactuca, hydrargyri, bichloridi, and solutions of morphias hydrochloras lactucarium, lauro-cerasus, lauri baccse, linum cath., lixivus and acetas. The liquor ammoniac must be diluted, liquor cinis, lupulina, malva, marmor, matico, melissa, menyanthes, ammonias acetatis concentrated, arsenical solution made ten mori succus, mucuna, origanum, ossa, petroleum, plumbi carb., times weaker, liquor potassa? and liquor potassa3 carbonatis plumb, ox. rubrum, potassse bichromas, potass. carb. impura, diluted with one measure of water; the diluted acids mixed rhamni succus, saccharum commune, sacch. lactis, sagapenum, with three parts of water. This would very much simplify salicis cortex, sassafras, simaruba, spigelia, spiritus pyroxilicus, prescribing, and make dispensing safer. Graduated solutions spongia, stannum, tapioca, terebinthina veneta, ulmus, viola. In of drachm strength may be made of the active principles of all seventy-four. the following vegetables :-hyoscyamus, conium, aconite, hem- This would make a great clearance, after which we should lock, tobacco, lobelia; also of quina and cinchona. Resinous be able to see our way better. Half of the list are superfluous medicines, as guaiacum, jalap, scammony, perhaps rhubarb, -i.e., rendered unnecessary by the existence of better drugs may be exhibited in solution by means of alkali, as I have else- of the same kind. The others are useless, or nearly so. I where recommended. These alkaline drachm solutions would shall be glad, if called upon, to give my especial reasons for be far more easy of absorption than the undissolved resin, wishing to expunge any particular member of the foregoing which must undergo the action of an alkali before it can pass list. into the blood. With regard to the formulae, an amalgamation must of Along with this plan of drachm solutions, it would be highly course be made, and all discrepancies must cease. As far as desirable that tinctures for internal use should be brought to a possible, the present London formu]ae may be retained, because uniform standard of two drachms for a dose, and all infusions, liable to very little exception. But their number, as I have decoctions, and mixtures, to a dose of one ounce. The tinctures said, may be materially curtailed by the removal to the materia of cantharides, aconite, opium, conium, stramonium, &c., being medica list of those pure chemicals of which it is unnecessary thus diluted, would be no longer sources of danger. The solu- to prescribe the mode of preparation. Most of the additions tions not intended for internal use should be kept in a separate to the last London Pharmacopoeia were wisely made. But the part of the druggist’s shop, and labelled Poison. This seems strained preparations of the gums are objectionable, as in the to me to form a simple solution of a pregnant question that has process the essential oil is partly lost. Linimentum saponis is been much agitated of late. solid at ordinary temperature, and requires to be altered. 8. The object of the changes which I have recommended may I may mention some drugs and forms at present peculiar to be stated in one word as simplification. Out of manifold re- either the London, Edinburgh, or Dublin Pharmacopoeias, but forms on a subject which has much engaged my attention, I which should by all means be introduced into the new one. have culled a few of the more prominent, in order to present In the London Pharmacopoeia : atropia, its sulphate; phos- them to the notice of the profession. The British Pharma. phorus ; granati rad. cort.; sulphur precipitatum; the distinct copceia must soon be taken seriously in hand; but ample time oils of vegetables; the concentrated infusions (cinchona); tinct. must first be given to elicit all discussion that may pave the quins co.; the ammoniated tinct. colch. co. In the Edinburgh way for the compilation of a volume that, whatever its faults Pharmacopoeia we find filix mas. In the Dublin Pharmacopoeia, or its excellencies, must serve as our prescribing manual for- glycerina. I would exclude the valerianates of the Dublin many years to come. Let us hope that the result of these de- Pharmacopoeia, which are not to be relied upon; also the liberations, in the hands of a body of men who have been pulvis ferri of Quevenne, preferring much the saccharine carbo- selected as most worthy to represent all grades of the profession nate of the London Pharmacopoeia. ’ in the three kingdoms, will be worthy of them and of us. 7. What remedies and forms may most advantageously be ’, introduced in addition to those now remaining? On this point i Two rules be very great caution must be observed. may safely CASTRATION AND MUTILATION. laid down for our guidance. 1st. Remedies and forms exten- II sively used in practice, where not obviously irrational, should CASES SHOWING THE IMMUNITY OF INSANE PERSONS FROM be introduced. 2nd. Remedies and forms which may safely be INFLAMMATION AFTER INJURIES. recommended on sure theoretical grounds, or which chemical knowledge enables us to substitute for substances already in BY WM. C. HILLS, ESQ., M.R.C.S., Maidstone. use, may be included, but with greater caution. To the lists of preparations of the alkalies, the sulphurets ofi CASE l.-J. B-, a homicidal and suicidal maniac, had for potassium and sodium, which are an admirable means of ad- a occasioned ministering sulphur internally or externally, may be added; long period much anxiety in consequence of the also the phosphate and benzoate of ammonia, both advisable as severity of his symptoms. On the 29th of April, 1856, during having the power of keeping uric acid in solution in the urine. the temporary absence of his attendant, he castrated himself in To the of iron the lactate be and a preparations may added, the watercloset; a little of pointed lath to make tincture of the potassio-tartrate substituted for vinum ferri, using piece an in the which he with which is of very uncertain strength. For antimonial powder, ’, opening scrotum, enlarged by tearing the preparation of which is most unscientific, and which in the ’i his fingers so as to lay open each tunica vaginalis. The wound last London Pharmacopoeia is reduced to the verge of absolute bore the shape of a Y inverted. The exact way in which the inertness, a mixture of a small proportion of teroxide of anti- spermatic cords had been severed could not be ascertained; it mony with phosphate of lime may be adopted. In the prepa- seemed probable, however, that they had been jerked asunder, ration of mercurial pill and ointment the use of some old mass the naked testis being firmly in the hand. The re- to oxidize the quick metal should be prohibited, and about 1 per grasped moval of both testes was one he had thrown down cent. of protoxide of mercury, the chief active element of these ’, complete: compounds, may be incorporated instead. A tincture of chloro- I the pan, the other in a corner. The man was faint from the form, of about 10 per cent. strength, may be used instead of the shock, but no haemorrhage occurred, and no vessels required variable mixture prescribed so widely as " chloric ether." I tying. Sutures were used to hold together the torn scrotum 436 which became reunited in the course of a moderate suppuration, - without sloughing. The patient complained of great tender- it in the West Indies. ness in each inguinal canal, where there was swelling from Edward (——, aged twenty-four, a respectable young man, effusion in the course of the spermatic vessels. This swelling employed as a Government clerk at Trinidad, was admitted gradually subsided, and no ill consequences followed the violent under Dr.
Recommended publications
  • Palliative Care : the 400-Year Quest for a Good Death
    Palliative Care This page intentionally left blank Palliative Care The 400-Year Quest for a Good Death Harold Y. Vanderpool McFarland & Company, Inc., Publishers Jefferson, North Carolina ISBN 978-0-7864-9799-7 (softcover : acid free paper) ISBN 978-1-4766-1971-2 (ebook) ♾ LIBRARY OF CONGRESS CATALOGUING DATA ARE AVAILABLE British Library cataloguing data are available © 2015 Harold Y. Vanderpool. All rights reserved No part of this book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying or recording, or by any information storage and retrieval system, without permission in writing from the publisher. On the cover: clockwise from top left hospice nurse with patient (Stockbyte/Thinkstock); Doctor Onstine, medical doctor, making an examination, 1943 (Library of Congress); Doctor and nurse examining patient in hospital room (Digital Vision/Thinkstock); The doctor’s office on Transylvania Project, Louisiana, 1940 (Library of Congress); Intensive Care Unit (iStock/Thinkstock) Printed in the United States of America McFarland & Company, Inc., Publishers Box 6¡¡, Je›erson, North Carolina 28640 www.mcfarlandpub.com For Jan This page intentionally left blank Table of Contents Acknowledgments ix Preface 1 1: From Proclamation to Recognition: 1605–1772 5 2: Minute Details and Codified Conduct: 1789–1825 23 3: That Science Called Euthanasia: 1826–1854 39 4: Polarities Between Attention and Disregard: 1859–1894 58 5: Challenging the Overreach of Modern Medicine: 1895–1935 76 6: Never Say Die Versus Care for the Dying: 1935–1959 93 7: Times of Momentous Transition: 1960–1981 112 8: Progress, Threatening Seas, and Endurance: 1982–1999 140 9: Choices: 2000 to the Present 173 Epilogue 207 Chapter Notes 211 Bibliography 243 Index 265 vii This page intentionally left blank Acknowledgments Research on the topics in this history began when I wrote the first of two master’s degree theses as a Kennedy fellow in medical ethics and the history of medicine at Har- vard University.
    [Show full text]
  • Confessions of an American Opium Eater : from Bondage to Freedom
    Cornell University Library The original of tiiis book is in the Cornell University Library. There are no known copyright restrictions in the United States on the use of the text. http://www.archive.org/details/cu31924090935077 In compliance with current copyright law, Cornell University Library produced this replacement volume on paper that meets the ANSI Standard Z39.48-1992 to replace the irreparably deteriorated original. 2001 GforttcU Uttlnetaitg ffiibrarg Stljaftt, !N*ni lock CHARLES WILUAM WASON COLLECTION CHINA aWD THE CHINESE THE GIFT OF CHARLES WILLIAM WASON CLASS OF 1876 laiB ''^.^^^-^ ) : Confessions American Opium Eater From Bondage to Freedom Timely advised, the coming evil shun Better not do the deed than weep it done. — Trior. BOSTON James H. Earle 178 Washington Street 1895 Copyright, i8gS, By James H. Earle. Ail rights reserved. OOI^TEZSTTS. CHAPTER I. Preliminary i CHAPTER II. Concerning My Early Life lo CHAPTER III. My First Experiment with Opium 24 CHAPTER IV. Am I My Sister's Keeper ?—The Prodigal Daughter ... 33 CHAPTER V. At the Gaming Table — The Death of My Wife .... 41 CHAPTER VI. I Attempt to Break Away from the Opium Habit, Do not Suc- ceed, and Return to Gambling 47 CHAPTER VII. "Who Fell Among Thieves"—A Startling Experience . 51 CHAPTER VIII. I Enter the Maine General Hospital as a Patient ... 56 CHAPTER IX. I Attempt to Fight the Demon Morphia Single-Handed and Am Defeated 63 II OOlTTEilsrT'S. (COHTISUEDA CHAPTER X. A Dishonorable Lawyer — I Advocate My Own Case . 73 CHAPTER XI. How I Was Living . .... 78 CHAPTER XII. I Believe in God and Christ, but Have No Religion .
    [Show full text]
  • Wild Lettuce (Lactuca Virosa) Toxicity Sima Besharat,1,2 Mahsa Besharat,3 and Ali Jabbari4
    BMJ Case Rep. 2009; 2009: bcr06.2008.0134. Published online 2009 Apr 28. doi: 10.1136/bcr.06.2008.0134 PMCID: PMC3031874 Other full case Wild lettuce (Lactuca virosa) toxicity Sima Besharat,1,2 Mahsa Besharat,3 and Ali Jabbari4 Sima Besharat, Email: moc.oohay@pg_tarahseb_s Copyright 2009 BMJ Publishing Group Ltd Abstract BACKGROUND Iran grows a variety of herbs, some of which are processed for pharmaceutical purposes.1 Wild lettuce (fig 1), which is known as “Laitue vireuse” in French, “Wilder lattich” in German and “Allubbyne” in Arabic, is also known as “opium lettuce”. Its scientific name is Lactuca virosa; in Latin, lactuca means “milky extract” and virosa means “toxic”.2 A biennial herb, wild lettuce grows on the banks of rivers and on waste grounds to a maximum height of 6 feet, flowering in July and August.1 It has a smooth and light green, sometimes purple spotted, erect stem which springs from a brown tap root.2 It is cultivated in different regions of the world, such as Austria, France, Germany, Scotland and Iran.1 The whole plant is rich in a milky juice that flows freely when it is scratched. The juice has a bitter taste and a noxious odour. When dried, it hardens, turns brown, and is known as lactucarium. L virosa has been found to contain lactucic acid, lactucopicrin which is amorphous, 50–60% lactucerin (lactucone) and lactucin. Lactocerine is the main component of the lactucarium, which is a neutral insoluble material.1 Lactucarium is a diuretic, laxative and sedative agent which relieves dyspnoea, and decreases gastrointestinal inflammation and uterus contractions.
    [Show full text]
  • Plant Powers, Poisons, and Herb Craft
    PLANT POWERS, POISONS, AND HERB CRAFT BY DALE PENDELL Foreword by Gary Snyde, $21.95 US In 'Pharmako/Poeia, Dale Pendell offers a mesmerizing guide to psychoactive Alternative plants, from their pharmacological roots to the literary offshoots. "This is a Health/ book," writes Gary Snyder, "about danger: dangerous knowledge, even more Literature dangerous ignorance." Against the greater danger, ignorance, Pendell strikes a formidable blow, as he proves himself a wise and witty guide to our plant teach- ers, their powers and their poisons. "Dale Pendell reactivates the ancient connection between the bardic poet and the shaman. His Pharmako/Poeia is a litany to the secret plant allies that have always accompanied us along the alchemical trajectory that leads to a new and yet authentically archaic future." — Terence McKenna, author of True Hallucinations "Much of our life-force calls upon the plant world for support, in medicines and in foods, as both allies and teachers. Pendell provides a beautifully crafted bridge between these two worlds. The magic he shares is that the voices are spoken and heard both ways; we communicate with plants and they with us. This book is a moving and poetic presentation of this dialogue." — Dr. Alexander T. Shulgin, University of California at Berkeley, Department of Public Health "Pharmako/Poeia is an epic poem on plant humours, an abstruse alchemic treatise, an experiential narrative jigsaw puzzle, a hip and learned wild-nature reference text, a comic paean to cosmic consciousness, an ecological handbook, a dried-herb pastiche, a countercultural encyclopedia of ancient fact and lore that cuts through the present 'conservative' war-on-drugs psychobabble." - Allen Ginsberg, poet Cover design "Dale PendelFs remarkable book will make it impossible to and color work ever again underestimate the most unprepossessing plant.
    [Show full text]
  • Wild Lettuce Latin Name: Lactuca Virosa
    Wild Lettuce Latin Name: Lactuca virosa Also known as: Prickly Lettuce, Horse Thistle, Green Endive, Compass Plant, Poor Man’s Opium, Opium Lettuce Scientific Classification Wild varieties of lettuce have some percentage of narcotic sap (induces sleep or stupor and relieves pain without the addictive qualities of opiates) and among them Lactuca virosa has the greatest concentration of narcotic juice. Other medicinal varieties of lettuce include L. scariola (also commonly known as prickly lettuce) L. altissima, L. Canadensis (also called wild lettuce and commonly found in America) and L. sativa (known as garden lettuce). Cultivation of garden lettuce has significantly reduced the narcotic sap content, but the herb is still used as an ingredient for lotions to heal skin disorders caused by sunburn and coarseness. Family: Asteraceae – aster, daisy and sunflower family Compositae – in earlier classifications Genus: Lactuca – lettuce Species: L. virosa – bitter lettuce Influence on the Body (PRINCIPLE ACTIONS are listed in CAPITAL LETTERS) Blood & Circulation heart palpitations Body System LOOSENS CATARRH (inflamed and congested mucous membranes) • HARDENED MUCUS Digestive Tract bitter (stimulates digestive juices and improves appetite) • dyspepsia (indigestion) • colic (severe abdominal pain) • irritated gastro-intestinal tract • diarrhea • intestinal worms Eyes eyesight Infections and ERRATIC FEVER • diaphoretic (promotes perspiration) Immune System • Candida albicans (yeast infection) • whooping cough (also known as pertusis, a contagious
    [Show full text]
  • Prescription Medications, Drugs, Herbs & Chemicals Associated With
    Prescription Medications, Drugs, Herbs & Chemicals Associated with Tinnitus American Tinnitus Association Prescription Medications, Drugs, Herbs & Chemicals Associated with Tinnitus All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form, or by any means, without the prior written permission of the American Tinnitus Association. ©2013 American Tinnitus Association Prescription Medications, Drugs, Herbs & Chemicals Associated with Tinnitus American Tinnitus Association This document is to be utilized as a conversation tool with your health care provider and is by no means a “complete” listing. Anyone reading this list of ototoxic drugs is strongly advised NOT to discontinue taking any prescribed medication without first contacting the prescribing physician. Just because a drug is listed does not mean that you will automatically get tinnitus, or exacerbate exisiting tinnitus, if you take it. A few will, but many will not. Whether or not you eperience tinnitus after taking one of the listed drugs or herbals, or after being exposed to one of the listed chemicals, depends on many factors ‐ such as your own body chemistry, your sensitivity to drugs, the dose you take, or the length of time you take the drug. It is important to note that there may be drugs NOT listed here that could still cause tinnitus. Although this list is one of the most complete listings of drugs associated with tinnitus, no list of this kind can ever be totally complete – therefore use it as a guide and resource, but do not take it as the final word. The drug brand name is italicized and is followed by the generic drug name in bold.
    [Show full text]
  • Lactuca Serriola: Short Review of Its Phytochemical and Pharmacological Profiles Thukaa Z
    REVIEW ARTICLE Lactuca serriola: Short Review of its Phytochemical and Pharmacological Profiles Thukaa Z. Abdul-Jalil* Ph. D., Pharmacognosy and Medicinal Plants, Department of Pharmacognosy, College of Pharmacy, University of Baghdad, Iraq Received: 12th June, 2020; Revised: 15th July, 2020; Accepted: 30th August, 2020; Available Online: 25th September, 2020 ABSTRACT Lactuca serriola Linn (prickly lettuce) is a common weed in cultivated fields belong to the Asteraceae family. Its leaves are used as a vegetable, eaten raw, or cooked. The present review attempts to furnish a brief overview of pharmacognosy, traditional uses, phytochemical, pharmacological activities, and the industrial applications of the Lactuca serriola (L. serriola) that will further explore its potential using the scientific process. Notarized information on pharmacognosy, traditional uses, phytochemical, pharmacological activities, and industrial applications of the L. serriola was gathered from authenticated online sources, like Scopus, Google Scholar, Research Gate, Science Direct, Elsevier, PubMed, and Web of Science. Additional information was collected from traditional sources, such as, books, book chapters, journal articles, and scientific publications sourced from the college library. L. serriola has a conventional use in the treatment of headache, insomnia, nervousness, hypertension, palpitation, fever, etc. It has been found in a recent finding thatL. serriola contains active components that have biological functions in disease control. They display diverse
    [Show full text]
  • Psychoactive Natural Products: Overview of Recent Developments
    12 Ann Ist Super Sanità 2014 | Vol. 50, No. 1: 12-27 DOI: 10.4415/ANN_14_01_04 Psychoactive natural products: overview of recent developments István Ujváry REVIEWS iKem BT, Budapest, Hungary AND Abstract Natural psychoactive substances have fascinated the curious mind of shamans, artists, Key words ARTICLES scholars and laymen since antiquity. During the twentieth century, the chemical com- • ethnopharmacology position of the most important psychoactive drugs, that is opium, cannabis, coca and • mode of action “magic mushrooms”, has been fully elucidated. The mode of action of the principal in- • natural products gredients has also been deciphered at the molecular level. In the past two decades, the • psychopharmacology RIGINAL use of herbal drugs, such as kava, kratom and Salvia divinorum, began to spread beyond • toxicology O their traditional geographical and cultural boundaries. The aim of the present paper is to briefly summarize recent findings on the psychopharmacology of the most prominent psychoactive natural products. Current knowledge on a few lesser-known drugs, includ- ing bufotenine, glaucine, kava, betel, pituri, lettuce opium and kanna is also reviewed. In addition, selected cases of alleged natural (or semi-natural) products are also mentioned. O, mickle is the powerful grace that lies In herbs, plants, stones, and their true qualities William Shakespeare (Romeo and Juliet) INTRODUCTION Historical background of psychoactive natural During the past 200 years, there has been major pro- products research gress in our understanding of the composition and ef- The biochemical machinery of an organism generates fects of many psychoactive natural products, particular- many structurally related chemicals (Nature’s “combinato- ly those that have therapeutic uses.
    [Show full text]
  • A Review Study on Analgesic Applications of Iranian Medicinal Plants
    Asian Pac J Trop Med 2014; 7(Suppl 1): S43-S53 S43 Contents lists available at ScienceDirect Asian Pacific Journal of Tropical Medicine journal homepage:www.elsevier.com/locate/apjtm Document heading doi: 10.1016/S1995-7645(14)60202-9 A review study on analgesic applications of Iranian medicinal plants 1 2 3 2 2 Mahmoud Bahmani , Hedayatollah Shirzad , Maedeh Majlesi , Najmeh Shahinfard , Mahmoud Rafieian-Kopaei * 1Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran 2Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran 3Faculty of Nursery and Midwifery, Iran University of Medical Sciences, Tehran, Iran ARTICLE INFO ABSTRACT Article history: Numerous side effects of synthetic drugs have caused medicinal plants to be regarded in recent Received 21 Jul 2014 decades as a reliable source of new drugs. Regarding the analgesic effects of many plants that are Received in revised form 4 Aug 2014 pointed in traditional medicine of Iran, many studies have been performed in this field that have Accepted 20 Aug 2014 caused need to be reviewed. In this study, different methods of testing pain, analgesic activity Available online 19 Sep 2014 and possible compounds of medicinal plants and also the possible mechanisms actions of these T Keywords: plants are presented. he data presented in this review paper provide scientific information that might be used for isolation of potentially active compounds from some of these medicinal plants Analgesia in future. Antinociception Flavonoids Medicinal plants Pain 1. Introduction involving in pain conditions are partially or totally disabled. The United States Center for Healthcare Statics carried out Based on definition of international association of an eight-year study, demonstrating 32.8% U.S.
    [Show full text]
  • Butter Lettuce
    Butter Lettuce Also called Boston and Bibb lettuce, good-quality butter lettuce will have fairly large, loose heads with thick leaves and even green coloring. Scratch the stalk and smell. A sweet or bitter smell means sweet or bitter flavor. In 2009, Yuma County produced over 900 acres of Butter lettuce valued at over $950,000. Butter lettuce originated from the Mediterranean basin. Other va- rieties were developed as hybrids from the original genetic line. The two best-known varieties of Butter Lettuce in the US are Bibb and Boston lettuce. How do you tell them apart? Boston's leaves are wider and lighter green than Bibb's. The smaller Bibb is highly prized by gourmets, and it is the flavorful rose and red tinged varieties that 'steal the show' with taste and beauty. Bibb owes its name to John Bibb who developed this variety in Kentucky from Boston lettuce in the 1850s. Butter lettuce, as its name suggests, is so tender that it melts in the mouth like butter, particularly the heart, when the lettuce is picked. It forms a loose head of large leaves resembling an open rose. The name "Boston," though typically North American, may be found anywhere. The fla- vor of butter lettuce is very subtle: it lends itself to countless uses. Butter lettuce contains lactucarium which has effects similar to those of opium. Because of its sedative properties, it is recommended for treating insomnia, intestinal spasms and palpita- tions. It is said that the emperor Domitian "tortured" his guests at banquets by serving them a head of lettuce at the beginning of the meal.
    [Show full text]
  • Lactuca-Virosa-Wild-Lettuce.Pdf
    Wild Lettuce Species (Family) Other constituents Mannitol, proteins, resins and sugars . Lactuca virosa L. (Asteraceae/Compositae) Synonym(s) Food Use Bitter Lettuce, Lettuce Opium Wild lettuce is not used in foods, although the related Related Lactuca species include Lactuca sativa species L. sativa is commonly used as a salad ingre- (Garden Lettuce), Lactuca scariola (Prickly Lettuce), dient. Lactuca altissima and Lactuca canadensis (Wild Lettuce of America) Herbal Use Wild lettuce is stated to possess mild sedative, ano- Part(s) Used dyne and hypnotic properties . Traditionally, it has Leaf, latex been used for insomnia, restlessness and excitability in children, pertussis, irritable cough, priapism, dysme- Pharmacopoeial and Other norrhoea, nymphomania, muscular or articular pains, and specifically for irritable cough and insom- Monographs ,G7,G8,G4 ,G64) nia. (G BHC 1992 (G6) BHP 1996 (G9) Martindale 32nd edition (G43) Dosage (G36) PDR for Herbal Medicines 2nd edition Dried leaves 0.5-3.O g or by infusion three times (G6) daily . Legal Category (Licensed Products) (G37) Liquid extract 0.5-3.OmL (1 :1 in 25% alcohol) GSL three times daily . (G6) (G6,G22,G48,G60,G64) Constituents Loctucorium (dried latex extract) (BPC 1934) 0.3- All parts of the plant contain a milky, white latex (sap) 1 .0 g three times daily . which, when collected and dried, forms the drug known as lactucarium .(G33) Soft extract (BPC 1934) 0 .3-1 .0 g three times daily. Acids Citric, malic and oxalic (up to 1%) acids ; Pharmacological Actions cichoric acid (phenolic) .( ' ) In vitro and animal studies (2,G33) Alkaloids Hyoscyamine, later disputed . N- Lactucarium has been noted to induce mydriasis .(G6) methyl-(3-phenethylamine, also disputed.
    [Show full text]
  • Anticancer Activity of Lactuca Steriolla Growing Under Dry Desert Conditionof Northern Region in Saudi Arabia
    Journal of Natural Sciences Research www.iiste.org ISSN 2224-3186 (Paper) ISSN 2225-0921 (Online) Vol.3, No.2, 2013 Anticancer activity of lactuca steriolla growing under dry desert conditionof Northern Region in Saudi Arabia Eman Elsharkawy 1 and Mona Alshathly 2 1-*Department of Eco physiology, Desert Research Center Northern Border University-ARAR- Saudi Arabia, Chemical Department 2- Faculty of science for girls- King Abdulaziz University- Jeddah- Saudi Arabia, Northern Border University- ARAR- Saudi Arabia, Zoology Department. Abstract Medicinal herbs are also significant source of synthetic and herbal drugs. So far, pharmaceutical companies have screened more than 25,000 plants for anti-cancer drugs. So we done to discover the anticancer activity of the terpinoid compound isolated from terrestrial Saudi plants, the MeOH extract of the aerial parts of the plant lactuca steriolla family Asteraceae was in vitro investigated for cytotoxicity against HCT116, A549, HepG2 and MCF-7 cell lines, and resulted in vitro show high cytotoxic activity against breast cancer with for MeOH extract and good cytotoxicity against liver cancer of hexane extract, respectively, Organic extracts , were fractionated through classic chromatography. The steroids stigmasterol acetate, β-sitosterol and campesterol were identified in hexane extract. Triterpenes, germincol, lupeol, α-amyrin, β-amyrin, olean 18-ene, lupeol acetate were isolated from methanol extract. Steroids and 14b-perganane and 4- piprdenone were isolated from methanol extract and identified by GC-MS. while triterpenes identified byH 1 NMR and C 13 NMR. Essential oils of the fresh leaves were obtained by hydro distillation and analyzed by GC-MS Keywords : Asteraceae, Lactuca serriolla, triterpene, volatile oil, breast anticancer Introduction The Asteraceae family compasses the largest family of angiosperms with approximately 23,000 species, 1,535 genera and represents approximately 10% of all world flora .The plants of Asteraceae family are studied respecting their chemical composition and biological activity.
    [Show full text]