PLTW (STEM) Biomedical Science (BMS – H Forensics)

Summer Assignment 2015-2016

Welcome to PLTW (STEM) Biomedical Science Pathway.

PLTW (Project Lead the Way) Biomedical Science pathway is for the student who desires a more in- depth study of biomedical science that will incorporate various aspects of science, public health and math with an emphasis on both mastery and critical thinking/application skills. This is a fast-paced college level course (*Course Substitution Credit A PLTW course or sequence of courses substitutes for a program course—treated similar to college transfer credit https://www.pltw.org/university-partners. Students will have to apply for any transfer of credit on their own.) that requires much outside classroom preparation, independent and problem based learning.

A summer assignment is essential to a good foundation as we incorporate more reading across the curriculum and giving all students an opportunity to learn more about the general content prior to starting the course! This class requires a strong work ethic, problem based learning and the ability to work independently. This is a freshman college course. Let’s start strong by getting a head-start!

 Summer book to read: Demon in the Freezer by ISBN-10: 0345466632

Please make sure that you complete all parts of the summer assignment! No two students’ assignments should be identical and your work should not be copied directly from any of the sources you are using. When citing resources – Please use APA format citation and have a reference page. The assignment will be due on Wednesday August 5th 2015. Please Do Not wait until the end of the summer to start working! We look forward to having you in class!!

The PLTW BMS team

Expectations: i. Turn in your COMPLETED answers to the reading by Wednesday August 5th 2015 ii. You do not have to re-write the question. iii. Please number each response based on the chapter, page(s) # and question #. Your handwritten responses should be collated in a journal/notebook or 3 ring binder. iv. DO NOT SKIP or FLIP question sequences. v. You must write in complete sentences and respond to the questions thoroughly (*this is a part of learning how to communicate as a scientist). vi. ALL writing should be in ink – BLACK or BLUE ink pen only should be legible, uniquely your own and responses should be in complete sentences with facts supporting your evidence. vii. Reference page – in text citation and reference page (APA citation format). Wikipedia, encyclopedia, google, yahoo or search engines and non-peer reviewed sites are not reference sources.

PLTW – BIOMEDICAL SCIENCE SUMMER READING (*9th and 10th STEM students) The Demon in the Freezer Study Guide Questions (FOR EACH QUESTION – please note the Chapter, page(s) # and paragraph # when citing from the book to answer the question. Each question below should be referenced with chapter, page(s) # and specifics from the book. Additional research is required to answer most of the question in its entirety.)

1. How were the from the spinal tap tested? Explain 2. Describe the appearance of . Where does anthrax (Bacillus anthracis) grow best? Explain why. 3. What is a lymph node? Compare a healthy lymph node to the diseased lymph node. Explain

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4. What are “HOT” agents? Explain 5. When was officially eradicated? Officially where does the smallpox exist today? Name to additional location thought to illegally possess smallpox? 6. Why was there a greater concern about smallpox than there was about anthrax? Explain 7. The author uses a metaphor when making the statement, “The inflamed area in the back of his throat was no bigger than a postage stamp, but in a biological sense it was hotter than the sun.” What does the author mean by this? 8. Describe what is happening to Peter’s body….How do you feel as this is being read? Why? 9. What is different between smallpox and AIDS? Explain 10. What lessons were learned from Meschede Hospital regarding smallpox and ? Explain 11. Assume that you came down with smallpox…the initial case… What do you think the multiplier would be? (Hint: think about how many people you directly contact, SIR model) 12. VIRUS: What is a virus’s most important means of survival? What often happens when a virus jumps species? What is the ecological benefit of ? Explain 13. Given what you know about the transmission requirements of smallpox from the reading, why did the ring vaccination work? Explain 14. What is the significance in the statement; ”One by one the laboratories keeping smallpox sent their samples to America or Russia or destroyed them or said they had destroyed them.” 15. What and where is ? Define “Heating Up”. 16. What is ? Explain. 17. Why would we not revaccinate everyone in the USA based from the reading of the book? Explain. 18. Explain what is HeLa. What is unique about HeLa cells? 19. Explain the life cycle of Anthrax and why is this, “Not your mother’s Anthrax”? Explain 20. Describe the essence of the scientific method from the reading of this book. 21. Compare the pox virus genome to the human genome. 22. Do you agree with the author’s perspective in that there is a threat for small pox to be used as a weapon of terror? Support your viewpoint. 23. Are you for or against vaccines? Support your stance with data from the book and other resources. 24. Do you agree with the choice to not destroy the small pox virus? Defend your position. 25. RESEARCH: Were there any inaccuracies in the book that are now identified as incorrect/incomplete? State which section (Chapter, page and paragraph) and what is the new hypothesis or new information. (* Make sure that you note the page/chapter of the inaccuracy)

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