Curriculum Vitae Richard Béliveau
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Curriculum Vitae Richard Béliveau 2 A. EDUCATION Dr. Richard Béliveau Date of birth: 13/03/53 Scientific director, Chaire en prévention et traitement du cancer Nationality: Canadian P.O. 8888, Station Centre-ville Tél.: (514) 987-3000 ext. 8551# Montréal (Québec) H3C 3P8 FAX: (514) 987-0246 [email protected] www.richardbeliveau.org I. FORMATION AND ACADEMIC POSITIONS Emeritus Professor Université du Québec à Montréal 2015- Scientific director, Chaire en prévention et Université du Québec à Montréal 2012- traitement du cancer Research associate Segal Cancer Center 2006- Lady Davis Institute Jewish General Hospital Chairholder, Chaire en prévention et Université du Québec à Montréal 2004-2012 traitement du cancer Research associate Cancer Prevention Centre 2008-2013 Oncology department McGill University Member of the Jewish General Hospital Cancer Cancer Prevention Centre 2008-2013 Prevention Centre and the Division of Cancer Jewish General Hospital Prevention of the McGill Department of Oncology Chairholder, Chaire de neurochirurgie Centre hospitalier de l’Université 2005-2012 Claude Bertrand de Montréal Associated professor, Département de chirurgie Université de Montréal 2005-2012 Full Professor of biochemistry Université du Québec à Montréal 1984-2013 Adjunct Professor of physiology Université de Montréal 1987-2013 Director (Laboratory of Molecular Medicine) Hôpital Sainte-Justine 1996-2009 Member of the hemato-oncology department Hôpital Sainte-Justine 1995-2009 Member of the Group on experimental Jewish General Hospital 2001-2013 therapy of cancer Member of the vascular malformation unit Hôpital Sainte-Justine 2000-2009 3 Member of the Groupe de Recherche en Université de Montréal 1984-2013 Transport Membranaire Assistant Professor (Department of Pediatrics) Université de Montréal 1982-1984 Research Fellow (F.R.S.Q.) Université de Montréal 1982-1984 Post-doctoral Fellow (N.S.E.R.C.) Cornell University 1980-1981 Ph.D. (Biochemistry) Université Laval 1976-1980 B.Sc. (Molecular Biology) Université du Québec à 1973-1976 Trois-Rivières II. PRIZES AND AWARDS 1970 – Winner of the Concours National de Version Grecque et Latine. 1973 – Scholarship from the Organisme pour la Promotion de l'Olympisme. 1976 – Junior Scholarship from the Natural Sciences and Engineering Research Council (N.S.E.R.C.), Sciences 67. – Scholarship for the Medical Research Council of Canada. – Scholarship for Graduate Studies from the Government of Quebec. – National Scholarship from Imperial Oil 1976-78. 1977 – Senior Scholarship form N.S.E.R.C., Sciences 67 1979 – Traveling grant to attend the International Workshop on Membrane Bio-energetics (Detroit, July 1979). 1980 – Post-doctoral Fellowship from N.S.E.R.C., 1980-81. – Post-doctoral Fellowship from the Prêt d'Honneur, of the Société St-Jean Baptiste. – Post-doctoral Fellowship from the Fondation Girardin-Vaillancourt, 1980-81. 1982 – Research Scholar of the Fonds de la Recherche en Santé du Québec (F.R.S.Q.), 1982-84. 2006 – Prize of general public for the book « Les aliments contre le cancer » at 29e Salon du livre de Montréal 2006 – Silver Prize in the Special Interest Category, French-language Culinary books of the Canadian Culinary Book Awards, Cuisine Canada & the University of Guelph (with the book : Les aliments contre le cancer) 2007 – Prize « Diplômé émérite » of Université du Québec à Trois-Rivières 2007 – Prize « Ancien émérite » of Séminaire de Trois-Rivières 2007 – Prize « Grand diplômé » and medal « Gloire de l’Escolle » of Université Laval, Quebec 4 2007 – Prize « Pythagore 2007, prix de diplômé exceptionnel » in the categroy Sciences of health, Université du Québec à Trois-Rivières 2007 – Silver Prize in the Special Interest Category, French-language Culinary books of the Canadian Culinary Book Awards, Cuisine Canada & the University of Guelph (with the book : Cuisiner avec les aliments contre le cancer) 2008 – Chosen as « Le Grand livre du mois » Club d’actualité littéraire français, for May 2008 with the book : « Cuisiner avec les aliments contre le cancer » 2008 – Gold Gutenberg 2008, from Les artisans des arts graphiques de Montréal, with the book : « Cuisiner avec les aliments contre le cancer » 2009 – Prize of general public with the book « La santé par le plaisir de bien manger » at 32nd Salon du livre de Montréal 2010 – Prize of Excellence for a Television report for « Une révolution se prépare », from the television program « Découverte » 2012 – « Diplôme honorifique » Cégep de Trois-Rivières 2013 – "Médaille UQAM" in recognition of his longstanding career achievements as a professor 2014 – Honoured by Québécor as an outstanding author 2014 – Guest of honour at "Le Salon du Livre de Montréal" III. RESEARCH TRAINING 1973 – Participant in a student exchange, in France, organized by the office franco-québécois pour la jeunesse: training course on Scientific Hobbies. 1980-81 – Post-doctoral Fellow in the laboratory of Dr. Richard McCarty, Department of Biochemistry, Molecular and Cell Biology, Cornell University. IV. EXPERIENCE (Teaching and professional) 1973 – Research Assistant in the Biology laboratory of Dr. A. Aubin, Université du Québec à Trois-Rivières (U.Q.T.R.). 1974 – Research Assistant in the Limnology laboratory of Dr. L. Wong, Ontario Department of Environment. 1975 – Research Assistant in the Physiology laboratory of Dr. R. Ward, U.Q.T.R. 5 1976 – Research Assistant in the Laboratory of Dr. R. Leblanc, U.Q.T.R. 1978 – Teaching Assistant for a laboratory course on Metabolism and Biochemistry, Department of Biochemistry, Université Laval. 1981 – Lecturer, Department of Biochemistry, Cornell University, Ithaca, New York. 1982 – Assistant Professor, Department of Pediatrics, Faculty of Medicine, Université de Montréal. 1984 – Professor, Department of Chemistry, Université du Québec à Montréal. 1986 – Lecturer, Department of Pharmacology, Université Laval and Université de Sherbrooke V. AFFILIATIONS – American Association for Cancer Research – Groupe de Recherche sur les Protéines Membranaires, Université de Montréal – Membre de l’équipe de neurochirurgie-oncologie CHUM – Membre du groupe de thérapie expérimentale sur le cancer Hôpital général Juif – Member of the Jewish General Hospital Cancer Prevention Centre and the Division of Cancer Prevention of the McGill Department of Oncology Research Orientations − Interaction of drugs with P-glycoprotein − Drug delivery through blood-brain barrier − Angiogenesis and tumor growth − Pharmacological modulation of drug resistance in cancer − Matrix metalloproteases in diseases − Cancer prevention by diet − Blood coagulation and cancer − Role of caveolae in signal transduction − Proteomic analysis of serum 6 B. SUPERVISION AND TEACHING I. RESEARCH COLLABORATORS, GRADUATE STUDENTS AND POST- DOCTORAL FELLOWS Professor in sabbatical Dr. Gérard Plante 1991-1992 Dr. John Wilson 1996-1997 Post-doctoral Dr. Vincent Vachon Reconstitution of the renal phosphate 1987-1992 (McGill) Dr. Louise Rochon Glucose transport by brain capillaries 1989-1990 (Laval) Dr. Julie Lafond Phosphorylation of brain capillary proteins 1990-1991 Dr. Richard Desrosiers Structure-function of methyltransferases 1991-1992 Dr. Borhane Annabi Mechanistic aspects involved in MMP-2 1999-2001 activation Dr. Laurence Fenart Penetration of the blood-brain barrier 1999-2000 Dr. Anthony Régina Molecular characterization of endothelial 2000-2002 cells in brain tumors Dr. Claude Dagenais Drug transport in the blood-brain barrier 2000-2001 Dr. David Ratel MT1-MMP-mediated angiogenesis in fibrin 2003-2004 matrix. Links between homeostasis and angiogenesis Research Associates Dr. Sylvie Lamy Dr. Michel Demeule Research Assistants Annie Levert Alain Larocque Alain Zgheib Jean-Christophe Currie Sophie Koselko 7 Graduate Students Hanane Ibnoul-Khatib Electrogenicity of the renal reabsorption of phosphate M.Sc. 1986 Johanne Strévey Involvement of arginine residues in renal transport Ph.D. 1987 Michelle Bernier Molecular studies on ion coupling in membrane transport M.Sc. 1987 Denis Gingras Protein methylation and G-proteins Ph.D. 1993 Michel Demeule Molecular studies on cyclosporine P-glycoprotein in M.Sc. 1990 normal tissues Ph.D. 1993 Bruno Beaumier Kinetics of the renal transport of phosphate M.Sc. 1990 Lise Dallaire Studies on phosphate transport across the blood-brain Ph.D. 1993 barrier Paul Ménard Studies on the proteolysis of membrane enzymes M.Sc. 1989 Sybille Neidhart Trace element composition of tissues M.Sc. 1989 Marie-Claude Delisle Purification of the renal phosphate transporter Ph.D. 1994 Jean-François Pouliot Lipidation of blood-brain barrier proteins Ph.D. 1994 Marc Jetté Molecular studies on the renal adaptation to M.Sc. 1991 hypophosphatemia Ph.D. 1996 Dominique Boivin Purification and characterization of a protein M.Sc. 1992 methyltransferase from the kidney Ph.D. 1995 Julie Pelletier Aging and renal functions: role of protein methylation M.Sc. 1993 Edith Beaulieu Involvement of P-glycoprotein in human cancers Ph.D. 1998 Diane Bilodeau Protein methylation in the kidney Ph.D. 2000 Christian Boyer Immunodetection of Na+-coupled carriers Ph.D. 1997 Lucie Jetté Drug transport by brain capillaries Ph.D. 1997 Yansen Xiao Protein oligomerisation and renal transport M.Sc. 1995 Ph.D. 2001 Wei Lin Chemical modification of methyltransferases M.Sc. 1995 André Dugré Limited proteolysis of the renal phosphate carrier M.Sc. 1995 Lise Tremblay Characterization of the renal tyrosine protein kinases Ph.D. 1994 Éric Vincent Involvement of cysteines is the renal phosphate