Brief for the Appraisal of the Master of Science in Applied Bioscience
Submitted to the Ontario Council on Graduate Studies
May 13, 2005
VOLUME I: The Program
University of Ontario Institute of Technology
TABLE OF CONTENTS
Section Content Page VOLUME I Table of Contents 2 1. INTRODUCTION 1.1 Brief Listing of Program 4 1.2 Background 4 1.2.1 Other Programs 4 1.2.2 Graduate Program Demand 5 1.3 Mission 6 1.4 Program Overview and Objectives 6 1.5 Method Used for Self-Study 10 1.6 Fields in the Program 10 1.7 Review of Concerns from Previous Appraisal 11 1.7 Special Matters and Innovative Features 11 2. THE FACULTY 2.1 Faculty by Field 14 2.2 External Operating Research Funding 18 2.3 Graduate Supervision 19 2.4 Current Teaching Assignments 20 2.5 Commitment of Faculty Members from other graduate 24 programs and/or other institutions 3. PHYSICAL AND FINANCIAL RESOURCES 3.1 Library Resources 25 3.2 Laboratory Resources 25 3.3 Computer Facilities 27 3.4 Space 27 3.5 Financial Support of Graduate Students 28 3.5.1 Sources of Funding for Graduate Students 28 3.5.2 Financial Counselling 30 3.5.3 Annual Reporting 30 4. PROGRAM REGULATIONS AND COURSES 4.1 Intellectual Development and Educational Experience of the 31 Student 4.2 Program Regulations 33 4.2.1 Part-time Studies 33 4.2.2 Admission and Language Requirements 33 4.2.3 Degree Requirements 35 4.2.4 Program Map 35 4.2.5 Course Offerings and Frequency 35 4.2.6 Progress Reports 35 4.2.7 Thesis Evaluation Procedures 36 4.3 Total Graduate Courses Listed and Level 36 4.4 Graduate Course Descriptions and Outlines 37 5. OUTCOMES 5.1 Enrolment and Graduations 47 5.2 Employment 47
Master of Science - Applied Bioscience 2 University of Ontario Institute of Technology
TABLE OF CONTENTS continued…
Section Content Page 5.3 Publications 47 5.4 Projected Graduate Intake and Enrolments 47 Appendix A: Library Resources Appendix B: Additional Information 1 Degree Level Summary 56 2 Program Comparisons 60 3 Resource Renewal and Upgrading 70 4 Program Design and Credential Recognition 72 5 Applicant Acknowledgement and Agreement 73
VOLUME II Curricula Vitae – Faculty Members Barsby, T. Bonetta, D. Byrne, C. Forrester, S. Green-Johnson, J. Holdway, D. Jones-Taggart, H. Naumkin, F. Paal, K. Sanchez, O. VOLUME III Curricula Vitae – Prospective Assessors Atkinson, Jeffrey Burka, John F. Curry, R. Allen Dixon, D. George Metcalfe, Chris Mulligan, Lois Schraft, Heidi Van Der Kraak, Glen
Master of Science - Applied Bioscience 3 University of Ontario Institute of Technology
1. INTRODUCTION
1.1 Brief listing of program
The University of Ontario Institute of Technology (UOIT) proposes to offer a graduate program leading to the degree of Master of Science (M.Sc.) in Applied Bioscience. Students will obtain their degree through successful completion of a thesis and specified course requirements. The expected length of time for degree completion is 24 months.
The program is planned to be launched by the Faculty of Science in September, 2006, or as soon as practical after all necessary approvals are obtained.
1.2 Background
The University of Ontario Institute of Technology is Ontario’s newest university. UOIT accepted its first undergraduate students in the fall of 2003.
The Faculty of Science offered its first undergraduate programs in Physical Science (with specializations in Physics, Chemistry and Mathematics) and Biological Science (with specializations in Pharmaceutical Biotechnology and Environmental Toxicology) in the fall of 2003. Since then, UOIT has received Ministerial consent to offer honours baccalaureate science degrees in Physics, Chemistry, Energy and the Environment (with Chemistry and Physics streams), Biological Science - Life Sciences stream, Computing Science and Forensic Science. Proposals for a degree in Applied and Industrial Mathematics as well as a Medical Physics specialization in the BSc in Physics, and two new specializations (Biological Chemistry and Pharmaceutical Chemistry) in the BSc in Chemistry program are currently under review by PEQAB. In addition, the Faculty of Science offers service and elective courses to other faculties in the University.
With the rapid growth and success of the undergraduate science programs at UOIT, the Faculty of Science is ready and able to expand into the graduate program area by offering MSc programs.
The University's Faculty of Health Sciences has also contributed to the development of this proposal and will participate in its implementation. This Faculty currently offers an Honours Bachelor of Science in Nursing and an Honours Bachelor of Health Science with both a complementary (general) model and a specialization in Medical Laboratory Science.
1.2.1 Other programs
There are currently no other graduate level programs offered by the Faculty of Science. A Master of Information Technology Security (MITS), UOIT's first graduate degree, is scheduled to be offered by the Faculty of Business and Information Technology beginning in September 2005. The Faculty of Science is also preparing a proposal for a MSc in Modelling and Computational Science for submission in 2005 to the Ontario Council on Graduate Studies.
Master of Science - Applied Bioscience 4 University of Ontario Institute of Technology
1.2.2 Graduate program demand
Today, knowledge has become the critical basis of competitive advantage among many industries and world economies. Indeed, about a third of the growth rate in per capita income is attributable to technological innovation. The source of most technological advances is university research, which generates the knowledge that leads to eventual breakthroughs. In Canada, universities are responsible for 34% of the research and development activity in the country1. This figure is likely to increase as our knowledge based economy continues to grow. To maintain its competitiveness, Canada will need to build on its intellectual resources by increasing its efforts towards science education and training. Part of these efforts will be to create and expand graduate training in areas where there is strong industry demand.
The current and future labour force in the biotechnology and pharmaceutical industries will require more individuals with interdisciplinary research skills. In light of this, the Applied Bioscience program at UOIT will provide unique interdisciplinary training in chemistry and biology, allowing students to develop a broad scientific perspective. At the same time, students will gain the depth of knowledge needed in their chosen areas of specialization. The ‘department-free’ environment at UOIT provides a unique opportunity for creating a program with this interdisciplinary scope. The program is expected not only to attract many students from outside the university, but also some of UOIT’s students that will be graduating in 2007.
1Organisation for Economic Co-operation and Development. Main Science and Technology Indicators (MSTI): 2004/2 edition
Master of Science - Applied Bioscience 5 University of Ontario Institute of Technology
1.3 University Vision, Mission and Values
VISION
The University of Ontario Institute of Technology is an innovative and market-oriented institution, pursuing inquiry, discovery and application through excellence in teaching and learning, value-added research and vibrant student life.
MISSION
• Provide career-oriented undergraduate and graduate university programs with a primary focus on those programs that are innovative and responsive to the needs of students and employers. • Advance the highest quality of research. • Advance the highest quality of learning, teaching, and professional practice in a technologically enabled environment. • Contribute to the advancement of Ontario and Canada in the global context with particular focus on Durham Region and Northumberland County • Foster a fulfilling student experience and a rewarding educational (work) environment. • Offer programs with a view to creating opportunities for college graduates to complete a university degree.
VALUES
Integrity and Respect We will treat each other with dignity, including those with challenges.
Honesty and Accountability Our actions reflect our values, and we are accountable for both.
Intellectual Rigour We strive for excellence and challenge convention.
1.4 Program Overview and Objectives
Life science research today is increasingly interdisciplinary. This trend has been driven in part by a greater reliance on chemical techniques in biological research; indeed, techniques that were once strictly the domain of chemists are now also part of the repertoire of many biologists. Given the success and new research opportunities that this approach has demonstrated, the interdependence of chemistry and biology can only be expected to increase in the future. However, in contrast to this general trend, graduate science education in biology has lagged behind, and most other graduate programs fail to provide training to students in both biology and chemistry. The UOIT environment provides a unique opportunity to provide an integrated educational experience in both fields. The primary objective of the Applied Bioscience program is to train students to become high-quality researchers at the interface between chemistry and biology, with competence in both of these subjects and the ability to tackle interdisciplinary problems and to work independently and successfully within collaborative networks. The program will equip students with a wide array of both practical and
Master of Science - Applied Bioscience 6 University of Ontario Institute of Technology conceptual scientific skills that will prepare them for leadership roles in the life sciences. These goals will be achieved through independent research and rigorous interdisciplinary coursework. The program will bring together students and faculty from a variety of scientific backgrounds, which will further enrich the learning experience of the students. In addition, in keeping with the UOIT’s strategic plan, research will be aimed at creating innovations that will improve the lives of Canadians.
The two main fields of research in the Applied Bioscience program (ABP) are Biomolecular Science and Environmental Science and Health (ESH). Biomolecular Science focuses on the use of molecular and cellular tools to investigate new approaches for combating infectious organisms and disease; biomaterials and bio-based products; drug discovery, drug formulation and site-specific drug delivery; and mechanisms of action of pharmaceuticals at the cellular and molecular level. The field of Environmental Science and Health includes an emphasis on environmental toxicology, whose goal is to determine the implications of external toxicants on the health of organisms and the discovery of indicators for environmental problems and methods to lessen human exposure to toxins. In addition, researchers in the ABP will investigate the pathophysiology of environmental disorders and the micro and macro environmental factors causing cancer.
The Applied Bioscience program is a unique collaborative program involving faculty in the Faculties of Science and Health Sciences at UOIT. The participating faculty members are made up of an interdisciplinary network of chemists, biologists and health scientists. Graduate students participating in this program will therefore be exposed to interdisciplinary research while they undertake their thesis projects in laboratories at UOIT, many of which are funded by NSERC or CIHR.
Research in Biomolecular Science will provide the technical training required for employment.
Employers such as those in the pharmaceutical and biotechnology industries, government and academia require graduates with a wide range of research expertise. The Applied Bioscience program will provide students with a wide range of research skills and expertise in techniques used for: • bioassays and toxicity testing • biomonitoring • assessing cellular activity and cell interactions at the molecular level • the isolation and characterization of biochemicals • biotechnology (heterologus gene expression)
Students will also receive hands-on experience with state-of-the-art analytical and biological instrumentation, such as: • Nuclear Magnetic Resonance (NMR) Spectrometer • Infrared (IR) Spectrometer • Ultraviolet (UV) Spectrometer • High Pressure Liquid Chromatograph (HPLC) • Ultra Performance Liquid Chromatograph (UPLC) • Gas Chromatograph (GC) • Mass Spectrometer (in tandem with UPLC or GC) • microarray and protein mass spectrometer • DNA microinjection
Master of Science - Applied Bioscience 7 University of Ontario Institute of Technology
Research in Environmental Science and Health will allow students to bridge laboratory- based discovery with community-based applications.
Environmental sciences will be complemented by a health component that:
a. addresses real or potential effects of environmental factors to health b. informs and educates the community at large on these issues c. develops science & health researchers with strong awareness & skills to perform research connecting the environment & human health.
In Ontario, various undergraduate and graduate programs focus on the general area of environmental sciences, but have not yet developed strong graduate streams focusing on Environment, Science & Health interactions. This is a gap which we intend to fill. At UOIT, a technology- and community-oriented university, we are building a unique group that encourages faculty members from different disciplines to closely collaborate. The Faculties of Science and Health Sciences combine a diverse group of expertise in, among others, environmental toxicology, chemistry, physics, mathematics, computational science, microbiology and immunology, nutrition, mental and community health, pathology, molecular biology and cancer research. This provides a very good assembly to build a graduate program that will pursue research in environmental sciences and health.
This program will be developed with local, regional and national interests in mind. The region of Durham has a very diverse environment, with many unexplored environmental issues that provide ideal grounds for research. Also, in this region there is a combination of industrial, rural, nuclear, socioeconomic and geographic conditions that are quite unique. Research in this region will be of benefit to the community at large and to the national and international research community.
The objectives of the MSc program will be achieved through a combination of course work, supervised research, a research seminar, and a research thesis.
Program Learning Outcomes
Graduates of the program will have reliably demonstrated the ability to:
• demonstrate specialized knowledge and understanding of essential facts, concepts, principles, and theories in a specific area of advanced study.
• apply the knowledge gained in their studies to specific research questions
• demonstrate a critical awareness of current problems and new knowledge about a particular area of applied bioscience research
• interpret current research trends and suggest future research avenues within the fields of applied bioscience
• understand the connections between biology, chemistry, and health sciences and acknowledge the value of diverse interpretations, methods, and disciplines in solving research problems
Master of Science - Applied Bioscience 8 University of Ontario Institute of Technology
• be able to work in research teams that span a range of expertise in chemistry and biology, and work collaboratively with scientists in other disciplines
• identify practical implications of applied bioscience research for both the scientific community and the general public
• use established techniques of research and enquiry to formulate specific research questions, propose and test hypotheses, determine methodologies, and interpret results
• recognize and be guided by social, professional, and ethical expectations and concerns involved in advanced education and research.
• demonstrate safe and competent use of laboratory tools, equipment and techniques, including cutting-edge technology in Biology and Chemistry, to support research activities
• communicate conclusions of their research clearly and effectively to both specialist and non-specialist audiences
• demonstrate qualities and transferable skills necessary for employment
• act independently to plan and implement activities to advance their knowledge and skills
These objectives will be achieved through courses dealing with key areas and necessary research skills in Applied Bioscience, participation in UOIT’s Science Colloquium Series, focused research training under the guidance of a research supervisor and supervisory committee, and the completion of a thesis that contributes to new knowledge. Course assignments will include written reports, oral presentations, review and critical analyses of professional literature and research.
Relationship of proposed program to unit academic plans
From its inception, the Faculty of Science has had no departments, and has emphasized interdisciplinary activity in its teaching and research. This includes team-teaching of courses cutting across disciplines. In addition, the Colloquium Series in the Faculty of Science, initiated in Fall, 2004, emphasizes interdisciplinary research and is an ongoing focal point for research interaction among faculty, postdoctoral fellows and research visitors. From the beginning, the Faculty of Science has built a strong core of research-oriented faculty in various areas of biology and chemistry who are expected to form collaborations with each other in both research and the training of graduate students. Research laboratories of several Health Science researchers supporting the proposed program are physically located within the laboratory infrastructure of the Science researchers, and one faculty member (Jones-Taggart) holds a 25% joint appointment in Science.
The Master’s program in Applied Bioscience will provide graduate training to interested and capable UOIT undergraduate students in the Faculty of Science in areas relevant to our honours B.Sc. degree in Biological Science (with specializations available in Environmental Toxicology, Pharmaceutical Biotechnology and Life Sciences), Chemistry (with specializations proposed for Biological Chemistry and Pharmaceutical Chemistry), or in areas complementary Master of Science - Applied Bioscience 9 University of Ontario Institute of Technology to our honours degree programs offered in the Faculty of Health Sciences.
Preparation for PhD studies
The Applied Bioscience Program will prepare students for PhD studies in various areas in biological, chemical, health and life science. Depending on the background of the student, the proposed program is more than sufficient to ensure access to the PhD programs in these areas of most universities across the country.
In terms of academic background and scholarly activities, the program will prepare students for the challenges of doctoral studies. The program in general will provide students with high- quality graduate courses and current-interest research problems, from which results will be expected to be published in peer-reviewed journals. Furthermore, there will be ample opportunities for scientific communication in both written and oral formats (eg., delivery of papers at conferences), and exposure to cutting-edge research from both the UOIT faculty and numerous visiting academics and professionals via the ongoing Science Colloquium and Seminar Series.
1.5 Method used for the self-study as well as the preparation of the brief, including faculty and student input and involvement
This brief was prepared by a Graduate Committee of members from UOIT's Faculties of Science and Health Sciences.
Graduate Committee Members of the Faculty of Science: Todd Barsby Dario Bonetta Sean Forrester Julia Green-Johnson Douglas Holdway Fedor Naumkin Krisztina Paal
Graduate Committee Members of the Faculty of Health Sciences: Carolyn Byrne - Dean, Faculty of Health Sciences Holly Jones-Taggart Otto Sanchez
The appraisal has gone through thorough reviews by the Faculty Council of the Faculty of Science, the Associate Provost, Research and Graduate Studies, the Curriculum and Program Review Committee, and the Academic Council of UOIT.
1.6 Fields in the program
The two fields of focus in the Applied Bioscience program are:
• Biomolecular Science • Environmental Science and Health
Master of Science - Applied Bioscience 10 University of Ontario Institute of Technology
1.7 Review concerns expressed in previous appraisal and actions taken
As this is an application for a new program, this section is not applicable.
1.8 Special matters and innovative features
The proposed MSc in Applied Bioscience program has a number of unique features which make it attractive for prospective students, and which are outlined below.
Tier 1 Canada Research Chair The University of Ontario Institute of Technology is quickly building a reputation for research excellence, which is expected to attract excellent graduate students. In recent months, UOIT faculty members have received high-profile recognition for their work in a number of areas. As a recent example, on Nov. 12, 2004, Douglas Holdway, a professor in the Faculty of Science, was awarded a Tier 1 Canada Research Chair in Aquatic Toxicology by the federal government. Dr. Holdway will receive a total of $1.65 million in research funding over seven years, including a $125,000 infrastructure grant from the Canada Foundation for Innovation (CFI) and $125,000 in matching funds from the Ontario government. Dr. Holdway’s research focuses on the impact that very brief, or “pulse” exposure to toxic compounds has on aquatic life.
Interdisciplinary Focus Major advances in fundamental knowledge often result from interdisciplinary research approaches and collaborations. The interdisciplinary research environment underlying the proposed program has the potential to result in important practical applications and will provide our students with a unique research perspective to foster their scientific training and outlook. The UOIT infrastructure, with an interdisciplinary Faculty of Science with strong links to Health Science and to other Faculties, provides a unique opportunity to expose students to a research environment involving multiple overlapping and complementary areas of research expertise. The proposed program is significant in that it brings together an interdisciplinary network of chemists, biologists and health scientists who will strive to focus their research interests on common questions. This focus will help students to understand the connections between biology, chemistry and health sciences and to appreciate the value of diverse interpretations, methods and disciplines in identifying and solving research problems in the biosciences.
An additional benefit of the inherent structure of the Faculty of Science, with no traditional departments, is the expertise and collaborative support of other members of the Science Faculty for the proposed program. These include Dr. Luciano Buono, an assistant professor in the Faculty of Science whose research deals with the theory of nonlinear dynamical systems and their biological applications, and the Dean, Dr. William Smith, who has extensive research experience in molecular-based and macroscopic physiological modeling. Both have strong interests in bioscience and are keen to serve on appropriate advisory committees in the Applied Bioscience program.
The interdisciplinary nature of the program will also benefit from the high degree of interaction between Science and Health Science faculty members. In addition to the full participation of the faculty members listed in Table 2-1, collaborative support from other faculty members will be provided (Dr. Moira Grant, Dr. Ellen Vogel), also in the form of service on appropriate advisory committees and lectures on specific topics in graduate courses. The Faculty of Health Sciences will contribute expertise to the Environmental Science and Health field in the
Master of Science - Applied Bioscience 11 University of Ontario Institute of Technology following ways:
• population health, workplace & community-based research (Carolyn Byrne, Moira Grant, Ellen Vogel) • cellular and molecular biology research (Holly Jones-Taggart) • qualitative and mixed-methods research (Ellen Vogel, Carolyn Byrne, Moira Grant) • food security, nutrition & health research (Ellen Vogel) • environment and cancer research (Holly Jones-Taggart, Otto Sanchez) • experimental pathology (Otto Sanchez) • health policy and practice (Ellen Vogel, Moira Grant)
More specifically, members of the Faculty of Health Sciences will pursue collaborative research avenues within Applied Bioscience, be members of graduate student advisory committees and participate in teaching and coordination of graduate courses in the program. In these roles, they will apply health-based research methodology, promote applications of ongoing research into health issues and enable opportunities for community-based studies. Specifically, Dr. Carolyn Byrne, Dr. Ellen Vogel and Dr. Moira Grant will be advisors in the areas of community health; mental health; food security and nutrition; mixed methods and qualitative research; and workplace health and health policy. Dr. Holly Jones-Taggart and Dr. Otto Sanchez will contribute with their experience in cancer research as well as cellular and molecular in vivo research methodology. Together, these faculty members will support research on any applications to individuals and/or the community.
Overall, we believe that the unique synergies in the Applied Bioscience program will provide many benefits to its graduate students, including: • unique exposure to graduate supervision by both science & health experts • a small, closely interactive & multidisciplinary research community • a regional community with a wealth of inherent research questions to address • new & incipient state-of-the-art technology & research infrastructure • exposure to and critical appraisal of environmental health issues
Leading Edge Facilities and Equipment Drs. Forrester, Barsby, Paal, Jones-Taggart and Bonetta have applied for a CFI New- Opportunities grant for the formation of a Pharmaceutical Research Network. The equipment to be purchased by this grant will be used both by graduate students in the individual laboratories of the Pharmaceutical Research Network and by other graduate students in the Applied Bioscience Program.
One of the main aims of the Pharmaceutical Research Network is to provide current and future researchers at UOIT access to the most advanced technology that will facilitate the discovery of novel therapeutic approaches to treat human disease. With this in mind, any new equipment and technology will provide UOIT with research capacity that is competitive both nationally and internationally. Specifically, this equipment will directly benefit the Pharmaceutical Research Network investigators, other principal core-faculty investigators at UOIT and future graduate students.
The University of Ontario Institute of Technology provides each of its students access to its Mobile Learning Environment. Every graduate student at UOIT will have wireless access to library resources, email, and the internet, in addition to other online services.
Master of Science - Applied Bioscience 12 University of Ontario Institute of Technology
Community-Based Focus UOIT is a new university in the Durham Region, an area which has little precedent for a research-focused academic institution within its geographic area and communities. As such, UOIT has a tremendous opportunity to engage the local community in the scientific process, especially through the Environmental Science and Health field. Currently, the Durham Region has a strong history of clinical research at its regional hospitals, and there are many ongoing pharmacological clinical trials carried out at the regional health facilities. These research efforts are facilitated by The Research Institute at Lakeridge Health and we foresee potential collaborations with this Institute and with the clinical researchers; this will benefit basic and clinical research both regionally and nationally.
Master of Science - Applied Bioscience 13 University of Ontario Institute of Technology
2. THE FACULTY
The research interests of the faculty cover a range of topics within Applied Bioscience, with a strong element of interaction between individuals; this should provide an excellent environment for graduate student training.
There are initially 10 full-time core professors involved in the proposed program. Since UOIT is a young university, there will be several additional appointments in the very near future.
In addition, UOIT is open to offering adjunct professorships both to external academics and to professionals with industrial ties.
Brief biographies are provided below for the faculty involved in the development and delivery of the proposed new program. The Curricula Vitae for all faculty are provided in Volume II of this submission.
Field 1 - Biomolecular Science
Todd Barsby (Assistant Professor, Faculty of Science) Dr. Barsby’s research integrates chemistry and biology in an effort to more effectively discover metabolites that may perform important ecological functions and that may be developed into drugs. He has published extensively in journals distributed by the American Chemical Society on the topic of antibiotics from microorganisms. He has been successful in major funding competitions, having received fellowships and awards from NSERC (PDF, PGS-B, Discovery), Fletcher Challenge Ltd, and the University of British Columbia (Graduate Fellowship). He has presented his research at national and international conferences, and has successfully patented his research. As well, Dr. Barsby has been active in moving chemistry from the laboratory to the field, and he has undertaken research expeditions to the United Kingdom, Western Canada, and the Caribbean. Dr. Barsby is one of only a few certified Aquanauts in Canada, having undertaken research in 2003 for 10 days in the Aquarius Undersea Research Laboratory, the world’s only undersea laboratory.
Dario Bonetta (Assistant Professor, Faculty of Science) Dr. Bonetta’s training and research background spans developmental biology, genetics, molecular biology, and the biochemistry of plant and microbial systems. He has recently been awarded a multi-year NSERC Discovery grant. To investigate the cell wall biology of plant and fungal systems he has held a Barbara McClintock PDF and a NSERC PDF at the Carnegie Institution of Washington at Stanford University, and has been a Research Scientist with Agriculture and Agri-Food Canada. He was an invited speaker at the British Biochemical Society’s Glycobiology meeting in 2002 and he has published extensively on plant development, biochemistry, and genetics in high profile journals, including Science. In 1998, Dr. Bonetta was awarded the Strauss Memorial Award for Molecular Biology at the University of Toronto.
Sean Forrester (Assistant Professor, Faculty of Science): Dr. Forrester’s research specializes on neurotransmitter-gated ion channels in parasitic nematodes, a novel field of research in Canada. He is a well recognized parasitology researcher and has received numerous awards for presentations of his research at both national and international scientific meetings. His specific expertise is in molecular biology, neurochemistry, molecular pharmacology and electrophysiology. In 2002, he was awarded the TWM Cameron award for excellence in Parasitology research from McGill University, which is Master of Science - Applied Bioscience 14 University of Ontario Institute of Technology awarded to the top student in Parasitology. In addition, his research has been published in well-known journals such as Biochemical Pharmacology and the highest ranked Parasitology journal (Molecular and Biochemical Parasitology). The laboratories in which he conducted his Ph.D. (Prichard lab, McGill University) and postdoctoral research (Pearce lab, University of Pennsylvania) are considered top parasitology labs in North America. He has a proven track record of success with major funding competitions, including a recent 5-year NSERC Discovery Grant, and was previously awarded an NSERC post graduate scholarship, an NSERC post doctoral fellowship, and major fellowships from McGill University (McGill Major Fellowship).
Julia Green-Johnson (Assistant Professor, Faculty of Science) Dr. Green-Johnson’s research deals with functional food components and their ability to influence the immune system, with a focus on their bioactivity in the mucosal microenvironment; characterization of bioactive products produced by lactic acid bacteria in milk and soy fermentations; microbe-host cell interactions, with an emphasis on the impact of probiotics and their bioactive products on cytokine and eicosanoid production and neuroimmune interactions in the context of the mucosal microenvironment. Additional areas of research include exercise and its effect on the human immune system, with a focus on effects on immunosenescence, and the impact of nutritional modification on bovine immunity. She was an invited speaker at the Montreal International Probiotic Symposium in 2004, and her research on immunomodulation by probiotics and other dietary components is funded through NSERC, the Ontario Ministry of Food and Agriculture (OMAF) and the Atlantic Innovation Fund (AIF).
Holly Jones-Taggart (Assistant Professor, Faculty of Health Sciences) Dr. Jones-Taggart’s research to date has concentrated on cell signaling and cancer cell metastasis. She completed postdoctoral training at the Ontario Cancer Institute and the Amgen Research Institute in Toronto. Her expertise in biological technology has resulted in many top publications in the areas of cell biology and physiology (Journal of Cell Biology) and a chapter in the recently published, A Laboratory Guide to the Mammalian Embryo. The link between bone cell differentiation signals and breast cancer metastatic behaviour is now the focus of her research. Recent manuscripts include those investigating the novel chemokine RANKL and its receptor in bone disease, published in the Annals of the Rheumatic Diseases.
Fedor Naumkin (Assistant Professor, Chemistry): Dr. Naumkin’s research concentrates on ab initio-based studies of nano-scale systems. It involves development of accurate and efficient theoretical/computational approaches and their use in prediction and analysis of the interrelations among structural, electronic, optical, electric, magnetic, and other properties of polyatomic systems. Such systems are represented by atomic/molecular complexes and clusters, species adsorbed on solid surfaces, molecular interfaces, etc. Practical applications of this research include new molecular species and materials, reaction design (in particular in geometry-restricted environments), catalytic and other processes, molecular (nano-) electronics, etc. The results are extensively published in highly rated journals and have a high Citation index (according to the Institute of Scientific Information). Most recent work (carried out in the University of Toronto) includes organic molecules on silicon surfaces, complexes of metal atoms and inorganic molecules, and is to be extended to bio-molecules. Dr Naumkin is also a referee for leading journals (J.Chem.Phys., J.Phys.Chem., etc.).
Master of Science - Applied Bioscience 15 University of Ontario Institute of Technology
Krisztina Paal (Assistant Professor, Faculty of Science) Dr. Paal has a breadth of expertise in biological and organic chemistry including site-specific covalent modification of proteins, ligand-protein binding interactions, enzymology, and organic synthesis. She has extensive international research experience that includes 4 years in the pharmaceutical industry. She is a co-inventor of a patented, innovative technology providing an alternative solution to the formulation of non-water-soluble drugs, and she actively participated in various stages of the development of a novel, water-soluble formula of paclitaxel (TaxAlbin®). Dr. Paal has published on the topics of developing hemoglobin-based red cell substitutes and, as a visiting scientist at the University of British Columbia, on enzymes involved in glycolipid metabolism. Her research efforts have resulted in scientific publications in top journals (Journal of the American Chemical Society) and two international patents.
Otto Sanchez (Associate Professor, Faculty of Health Sciences) Dr. Sanchez’s research encompasses cancer biology, with emphasis on the problems of carcinogenesis, metastasis and experimental therapeutics. His diverse educational and professional experience as a medical doctor and pathologist, combined with graduate studies in cancer cytogenetics and metastasis, allows him to focus on research that aims at linking cellular and molecular cancer events to their potential clinical impact. His expertise on murine models of cancer has led him to be a consultant and collaborator with various cancer research laboratories, which has led to the publications of six papers in 2004, most in high impact journals, and nineteen peer-reviewed papers in the last 5 years. He has received two awards from the American Association for Cancer Research Minority Scholar Program. Currently, Dr. Sanchez is a co-investigator in a CIHR grant to study the biology of osteosarcomas (2003- 2006), that was ranked first (out of 49 applications reviewed) by the Cancer A review panel in the March 2003 competition.
Field 2 - Environmental Science and Health
Todd Barsby (Assistant Professor, Faculty of Science) Dr. Barsby has expertise in both fields of the program. Please refer to his biography in the section above.
Carolyn Byrne (Dean, Faculty of Health Sciences) Dr. Byrne served as an investigator in two research units: the system-linked Research Unit on Health and Social Service Utilization, and the community-linked AIDS Resource Unit. Her clinical work as a nurse and psychotherapist is in the area of mental health, and she has considerable expertise in understanding depression as well as its impact on spouses and the capacity to parent. Her expertise in curriculum development and problem-based learning has garnished her international reputation and many honours such as the President's award for educational leadership at McMaster. She has been a consultant to schools of Nursing within Canada, the United States, England, Japan and South Africa.
Doug Holdway (Tier 1 CRC in Aquatic Toxiciology; Full Professor, Faculty of Science): Dr. Holdway’s research examines ecotoxicological impacts of contaminants upon aquatic organisms, populations and communities; development and application of biomarkers of contaminant exposure and effects in aquatic organisms; effects of contaminant pulse- exposure on reproduction and long-term population health in aquatic ecosystems; bioenergetics of xenobiotic detoxification processes in aquatic organisms and the development of rapid sensors of pathogens in drinking water. He is also supported by NSERC.
Master of Science - Applied Bioscience 16 University of Ontario Institute of Technology
Holly Jones-Taggart (Assistant Professor, Faculty of Health Sciences) Dr. Jones-Taggart has expertise in both fields of the program. Refer to her biography in the section above.
Otto Sanchez (Associate Professor, Faculty of Health Sciences) Dr. Sanchez has expertise in both fields of the program. Refer to his biography in the section above.
Table 2-1 lists the faculty members involved in the graduate program and identifies their research field, gender, home unit, and supervisory privileges. There are no expected retirements within the next seven years.
Table 2-1 Faculty Members by Field Ret. Supervision Faculty Name & Rank M/F Home Unit Fields Date Privileges Category 1 ESH Todd Barsby - Assistant M Science Full BMS Dario Bonetta - Assistant M Science Full BMS
Sean Forrester - Assistant M Science Full BMS Julia Green-Johnson F Science Full BMS -Assistant Douglas Holdway – Full M Science Full ESH Health Holly Jones-Taggart ESH F Science and Full -Assistant BMS Science Krisztina Paal – Assistant F Science Full BMS Health ESH Otto Sanchez - Associate M Full Science BMS Carolyn Byrne– Dean of Health F Full ESH Health Science and Full Science Category 3
Fedor Naumkin – Assistant M Science Full BMS
Fields
BMS - Biomolecular Science ESH - Environmental Sciences and Health
Category 1: tenured or tenure-track core faculty members whose graduate involvement is exclusively in the graduate program under review.
Category 3: tenured or tenure-track core faculty members who are involved in teaching and/or supervision in other graduate program(s) in addition to being a core member of the graduate program under review. Master of Science - Applied Bioscience 17 University of Ontario Institute of Technology
2.2 External operating research funding
Table 2-2 presents the external research funding that faculty members in the proposed program have received to date since 1998. Note that the funding listed represents only confirmed funding and is expected to increase as the faculty successfully secure additional funding. Since the first faculty started at UOIT in 2003, the funding in Table 2-2 for the years 1998 to 2002 represents funding secured by UOIT faculty while at other institutions.
Table 2-2: Operating Research Funding by Source and Year
Source
Year1 Granting Other Peer Contracts Others 4 Councils 2 Adjudicated 3
1998 $62,500 $581,259 1999 $52,410 $215,388 $21,000 $3,000 2000 $81,667 $56,500 $81,270 $3,000 2001 $81,667 $112,500 $34,439 2002 $85,667 $246,200 $98,545 2003 $153,750 $347,500 $15,000 $10,000 2004 $483,750 $130,000 $419,000 20055 $606,430 $176,000 $436,710 $1,607,841 $1,865,347 $250,254 $871,810 Totals
1 Calendar year. 2 NSERC; CFI, AAFC, CIHR 3 Ontario Ministry of Agriculture and Food; Australian Competitive Grants (Australian Research Council Dept. of Industry, Science and Tourism (DIST) Major Grant, Dairy Farmers of Canada, Canadian Foundation for Dietetic Research, Nova Scotia Health Research Foundation, Atlantic Innovation Fund, Ontario Ministry of Health and Long Term Care, Ministry of Health of Ontario, Ministry of Culture and Communication, Ministry of Community, Family and Children Services, 4 University start-up grants and other miscellaneous research funding. 5 Confirmed to date. In addition, faculty have applied for NSERC Research Tools and Instruments Grants and CFI New Opportunities Grants and CIHR.
Table 2-3 presents the total external research funding by field for 2003 to 2005. As with Table 2-2, the amounts in Table 2-3 represent only the confirmed funding and shall increase as the faculty successfully secure funding from the various sources listed above and from industry.
Table 2-3: Total External Operating Funding by Field – 2003 to 2005
Granting Councils Other peer Contracts Others adjudicated
Field 1 (BMS) $332,305 $441,000 $15,000 $495,000
Field 2 (ESH) $911,625 $212,500 $0 $370,710
Doctors Barsby, Jones-Taggart and Sanchez offer expertise in both fields of the program; therefore, their funding contributions have been apportioned equally to both areas.
Master of Science - Applied Bioscience 18 University of Ontario Institute of Technology Science Faculty members are actively applying for or have already obtained funding from the Natural Sciences and Engineering Research Council (NSERC) of Canada, the Canada Foundation for Innovation (CFI) and the Ontario Ministry of Agriculture and Food, among others. In addition, the faculty are active in securing research funding through industry contracts. As the number of faculty increases over the next few years, it is fully expected that the funding presented in Tables 2-2 and 2-3 will increase substantially.
2.3 Graduate supervision
Table 2-4 lists the completed and current numbers of thesis supervisions by faculty member. The table shows that the team is comprised of senior professors who have successfully graduated students and new professors who have not yet graduated students. A number of the faculty involved in the proposed program currently hold adjunct appointments at other universities, with graduate supervision capabilities.
Table 2-4: Completed and Current Numbers of Thesis Supervisions by Faculty Member
Completed Current
Member B.Sc M.Sc MHScN Ph.D PDF B.Sc M.Sc Ph.D PDF
Category 1
Todd Barsby
Dario Bonetta
Carolyn Byrne 7 3
Sean Forrester
Julia Green- Johnson 22 1 1
Douglas Holdway 8 3 11 2 2 2
Holly Jones-
Taggart
Krisztina Paal
Otto Sanchez
Category 3
Fedor Naumkin
Master of Science - Applied Bioscience 19 University of Ontario Institute of Technology
2.4 Current teaching assignments
Table 2-5 shows the planned teaching loads for the 2005/2006 academic year. Tables 2-6 to 2-9 show the faculty members' teaching assignments for academic years between 2001 and 2005. UOIT accepted its first undergraduate students in the 2003/2004 academic year.
Note: When the graduate program begins, a normal teaching load will consist of four single semester courses per year.
Table 2-5: Teaching Assignments for 2005/2006 at UOIT
Faculty Member Rank Undergraduate Graduate Comments CHEM2020U Introduction to Organic Chemistry CHEM2030U Analytical Chemistry Todd Barsby Assistant CHEM2130U Analytical Chemistry for Biosciences (shared lecture with CHEM 2030U) CHEM 1020U Chemistry II BIOL3050U Developmental Biology Dario Bonetta Assistant BIOL1020U Biology II BIOL3040U Physiology of Regulatory Systems BIOL1010U Biology I (50%) BIOL2840U Cell and Molecular Biology BIOL3020U Principles of Pharmacology and Sean Forrester Assistant Toxicology (50%) ENVS1000U Environmental Science (25%) BIOL1840U Biology for Engineers BIOL1010U Biology I (50%) Julia Green- BIOL2030U Cell Biology Johnson Assistant BIOL2830U Microbiology for Health Science
BIOL3030U Microbiology and Immunology BIOL2010U Introductory Physiology Douglas ENVS1000U Environmental Science (25%) Full Holdway BIOL3020U Principles of Pharmacology and Toxicology (50%) HLSC1200UAnatomy and Physiology I Holly Jones- Assistant HLSC1201U Anatomy and Physiology II Taggart BIOL2020U Genetics and Molecular Biology CHEM2010U Structure and Bonding CHEM2040U Thermodynamics and Kinetics (with PHY 2050U) Fedor Naumkin Assistant CHEM3040U Fundamentals of Physical Chemistry PHY2050U Thermodynamics and Heat Transfer CHEM1010U Chemistry I (2 sections) Krisztina Paal Assistant CHEM2120U Organic Chemistry Pathology I Otto Sanchez Associate Pathology II Comprehensive Anatomy and Physiology Dean, Faculty Carolyn Byrne Full of Health Sciences
Master of Science - Applied Bioscience 20 University of Ontario Institute of Technology
Table 2-6: Teaching Assignments for 2004/2005 at UOIT
Faculty Member Rank Undergraduate1 Graduate Comments CHEM 1800U Chemistry for Engineers CHEM 2030U Todd Barsby Assistant Analytical Chemistry CHEM 1020U Chemistry II BIOL 1020U Biology II Dario Bonetta Assistant ENVS1000U Environmental Science (team-taught course: 25%) BIOL 2840U Cell and Molecular Biology SCIE 1910U Participation in Science in Context (team-taught course) Sean Forrester Assistant ENVS 1000U Environmental Science (team-taught course: 25%) BIOL 1840U Biology for Engineers BIOL 1010U Biology I Julia Green- BIOL 2030U Cell Biology Johnson Assistant BIOL 1810U Biochemistry for Health Science SCIE 1900U Participation in Science in Context (team-taught course) BIOL 2010U Douglas Full Introductory Physiology Holdway ENVS 1000U Environmental Science BIOL 2020U Genetics and Molecular Biology Holly Jones- Assistant HLSC1200U Taggart Anatomy and Physiology I HLSC 1201U Anatomy and Physiology II CHEM 2010U Structure and Bonding CHEM 2040U Thermodynamics and Kinetics Fedor Naumkin Assistant PHY2050U Thermodynamics and Heat Transfer CHEM1010U Chemistry I Krisztina Paal Assistant CHEM 2020U Introduction to Organic Chemistry CHEM 1800U Chemistry for Engineers HLSC 2460U Pathophysiology I HLSC 2461U Otto Sanchez Associate Pathophysiology II Dean, Faculty of
Carolyn Byrne Full Health Sciences
Master of Science - Applied Bioscience 21 University of Ontario Institute of Technology
Table 2-7: Teaching Assignments for 2003/2004
Faculty Rank Undergraduate1 Graduate Location Member Todd Barsby Assistant Advanced Molecular Genetics Dario University of Assistant (team taught course: 15%) Bonetta Western Ontario Advanced Molecular Biology Sean Assistant Forrester BIOL 1820U Microbiology for Health Science Julia Green- CSCI 1000U Scientific Johnson Assistant UOIT Computing Tools (team member)
SCIE 1910U Science in Context (team member) BIOL 1010U Biology I BIOL 1020U Biology II Douglas CSCI 1000U Scientific Computing Full UOIT Holdway Tools (team member) (SCIE 1910U) Science in Context (team member) Pathophysiology and Pharmaco- Holly Jones- therapeutics: Relevance to University of Taggart Lecturer Nursing Practice Toronto
Fedor Physical Chemistry for Life University of
Naumkin Sciences (2nd yr course) Toronto Principles of Organic Chemistry Principles of Bio-organic Assistant Chemistry Krisztina professor Structure and Reactivity of Brock University Paal (sessional) Organic Molecules Bio-organic Chemistry Principles of Organic Chemistry NURS 1200U Anatomy and Otto Associate Physiology I UOIT Sanchez NURS 1201U Anatomy and Physiology II Dean of Faculty of Carolyn Full Health Sciences, Byrne UOIT
Master of Science - Applied Bioscience 22 University of Ontario Institute of Technology
Table 2-8: Teaching Assignments for 2002/2003
Faculty Rank Undergraduate1 Graduate Comments Member Todd Barsby Dario Bonetta Sean
Forrester NUTR 3413 Fundamentals of Biotechnology NUTR 4223 Sensory Julia Green- Analysis of Foods Acadia University, Johnson Assistant NUTR 2203 Food Wolfville, NS
Commodities One NUTR 2213 Food Commodities Two Biology 441F Biology 812F University of Prince Douglas Full Ecotoxicology Ecotoxicology Edward Island, Holdway Charlottetown, PEI Holly Jones- Taggart
Fedor Chemical Kinetics and University of Toronto Naumkin Dynamics (4th yr course) Krisztina Paal Pathophysiology for Nurse Practitioners Integrative Nursing School of Nursing, Otto Sanchez Assistant Practice Seminar McMaster University Integrated Biological Bases of Nursing Practice I Poverty and School of Nursing, Carolyn Byrne Full Homelessness McMaster University
Master of Science - Applied Bioscience 23 University of Ontario Institute of Technology
Table 2-9: Teaching Assignments for 2001/2002
Faculty Rank Undergraduate Graduate Comments Member Todd Barsby
Dario Bonetta Sean
Forrester NUTR 4223 Sensory Analysis of Julia Green- Foods Acadia University, Johnson Assistant NUTR 2203 Food Commodities Wolfville, NS
One Holly Jones-
Taggart AB310 Environmental RMIT-University, Douglas Toxicology Full Melbourne, Holdway AB207 Zoology I and II Australia AB100 Introductory Physiology Fedor Physical Chemistry for Life University of
Naumkin Sciences (2nd year course) Toronto
Krisztina Paal NURS PRAC 4P03 Pathophysiology for Nurse Practitioners HTH SCI 1CC7 Integrative School of Nursing, Otto Sanchez Assistant Nursing Practice Seminar McMaster NURSING 3U02 Integrated University Biological Bases of Nursing Practice I BIOLOGY 4F06 Senior Project School of Nursing, Carolyn Byrne Full Poverty and Homelessness McMaster University
2.5 Commitment of faculty members from other graduate programs and/or from other institutions
Dr. Fedor Naumkin is the only faculty member in the proposed program who will be teaching in another UOIT graduate program - the proposed MSc in Modelling and Computational Science. Faculty from other graduate programs and/or other institutions may be invited to participate as guest lecturers or participants in the Science Colloquium Series.
Master of Science - Applied Bioscience 24 University of Ontario Institute of Technology
3. PHYSICAL AND FINANCIAL RESOURCES
3.1 Library resources
The goal of the University of Ontario Institute of Technology library is to enrich the research, teaching, study, and conversation of the University by providing exceptional library and information services and facilities to support all academic programs.
The construction of a new, state-of-the-art library for the University of Ontario Institute of Technology was completed in the fall of 2004. Designed by internationally renowned Diamond and Schmitt Architects Incorporated, the 73,000-square-foot library serves students, faculty, and staff. The four-storey, $20.7-million library houses individual and collaborative learning spaces, research workstations, electronic classrooms, a round pavilion with a reading room and periodicals collection, and other facilities. It offers a variety of learning spaces to suit individual learning styles and user needs. Its design also allows for future enlargement, up to double the original size.
The University’s Mobile Learning Environment provides students with access to library resources anytime, from anywhere. Students are able to work individually or collaboratively anywhere in the building. Digital resources and complementary print collections are provided for students in both a physical and virtual environment. Librarians are available to provide students with the skills to navigate effectively through the information environment.
In addition to interlibrary loans, students will also have access to the resources available at the largest academic library in Canada, the University of Toronto Libraries, through a partnership program.
To keep faculty and students informed of the library’s continued growth and to provide easy access to resources, the UOIT Library staff have been constructing and revising its web site (www.uoit.ca/library) on an ongoing basis.
A more detailed discussion of the library resources is provided as Appendix A: Library Resources.
3.2 Laboratory Facilities
Each of the researchers in the Applied Bioscience program has been provided with at least a 64 sq/m laboratory in our newly-built Science Research facility. These laboratories contain two center islands that will accommodate 4 possible graduate students comfortably. Researchers conducting cell biology research have also been provided with a level 2 biosafety hood. Those students interested in aquatic toxicology will have access to the soon-to-be-completed 1390 sq/ft web lab, housing 12 large (1000 L) cold-water tanks, and 200 small (100 x 100 L and 100 x 10L) warm-water tanks for aquatic organisms. There are separate storage rooms for biology and chemistry equipment. The science teaching facilities have been equipped with the latest technology needed for research in molecular biology and chemistry. Graduate students will have access to all equipment in the teaching facilities.
Master of Science - Applied Bioscience 25 University of Ontario Institute of Technology
This equipment includes:
• Microscopes (fluorescent, compound, inverted and stereo, comparison microscope and comparison microscope (capable of digital imaging) • Molecular Biology equipment (gel electrophoresis, vacuum blotter, thermal cyclers, gel documentation system) • Histology equipment (microtome, cryotome, tissue processor and embedding centre) • Microplate Reader, with fluorescence, luminescence and spectrophotometric capabilities • UV and white light transilluminators • Centrifuges, including an ultracentrifuge and high speed • Tissue culture facility, autoclaves • Genetic analyzer • French press • X-ray film processor • Freeze-drier • Electroporation system • CO2 and general incubators • Biosafety cabinet level II • 4 gas chromatographs (with flame ionization detection) • FT-IR spectrometers • 400 mHz NMR spectrometer • HPLC with photodiode array detector • Ion Chromatograph • LC-MS and GC-MS, with electron capture and flame ionization detection capabilities • Atomic Absorption Spectrometers, with a graphite furnace accessory • Inductively Coupled Plasma Emission Spectrometer • UV-Visible spectrophotometers, with thermostatted cells • fluorimeter, with thermostatted cells
Graduate students will also have access to equipment provided by the researchers in the ABP. Our researchers have been provided with competitive start-up and matching funds to equip their respective laboratories with the latest technology in their fields. In addition, all researchers in the ABP are required to maintain a competitive research program and attract external funding. Faculty of Science researcher Dr. Holdway holds a CRC funded chair, in addition to NSERC funding; Dr. Green-Johnson is NSERC-funded for five years, and has also received funding from the Ontario Ministry of Agriculture and Food for three years. The junior faculty are high-quality researchers who are also NSERC or CIHR-fundable. In addition, Drs. Forrester, Barsby, Paal, Jones-Taggart, and Bonetta have applied for a CFI New Opportunities grant this year for the formation of a Pharmaceutical Research Network. The equipment to be purchased by this grant will be available for use by graduate students in the proposed program.
In addition, common areas of the Science research facility will accommodate shared common equipment, located near the Chemistry teaching laboratories (building A2) and Biology teaching laboratory areas (building A3). Students will also have access to a dark room, tissue culture room, and shared autoclave facility.
Master of Science - Applied Bioscience 26 University of Ontario Institute of Technology
3.3 Computer Facilities
As mentioned previously, all students will have wireless access to library resources, email, and the internet through UOIT’s Mobile Learning Environment. Individual supervisors will provide computer facilities for their MSc students. MSc students will have the option to subscribe to UOIT’s laptop program. UOIT’s laptop program provides students with a current model IBM laptop that is equipped with a suite of program specific software. In addition, UOIT has 240 desktop computers available to students in the Learning Commons and library.
Graduate students will have access to the following facilities:
• SHARCNET (Shared Hierarchical Academic Research Computing Network) facilities (both within and outside UOIT) for high-performance computing • Computational Science and Visualisation Laboratory for computer simulation and computation (expected, via a pending CFI New Opportunities Grant) • A local Linux xeon-based computer cluster • HP 7620 general-purpose computer
As a member of SHARCNET, UOIT faculty members and their research groups also have access to very significant computing capabilities. SHARCNET is a consortium of 9 universities and 2 colleges in Southern Ontario. At present, the large computational facilities are located at McMaster University, the University of Western Ontario and the University of Guelph. SHARCNET was successful in a recent 2004 CFI Innovation Fund competition, which will result in a significant expansion of the facility. Included in this expansion, UOIT will acquire a ‘development cluster’ of approximately 32 processors that will be located on-site. With the new funding, it is projected that SHARCNET will become one of the top 100 High-Performance Computing facilities in the world. Access to this facility by UOIT faculty and graduate students will provide them with the opportunity to study problems that would otherwise be computationally prohibitive.
As part of its mission, UOIT seeks to advance the highest quality of learning, teaching, and professional practice in a technology-enabled environment. All faculty and graduate students are provided with an account that gives them access to electronic mail facilities, the internet, the University's course management system (WebCT), library resources, etc. In addition, students can easily access information about a variety of student services and non-academic resources available to them.
3.4 Space
The Faculty of Science is located in UOIT’s Science Building (UA1). This building, first opened in September 2003 and extended for September 2004, features office space for faculty and graduate students in addition to research lab space. The current total research space allocated to Science is 1,496 m2. An additional 273 m2 has been allocated for faculty and graduate student offices.
Faculty members have private offices with telephone and computer lines to the University facilities. Graduate students will have access to shared office facilities and/or research labs. Because the graduate students will also be teaching assistants, they will be able to occupy work spaces that are currently assigned to teaching assistants who are hired on a contract basis. All offices and research spaces are wired for access to UOIT’s network. In addition, Master of Science - Applied Bioscience 27 University of Ontario Institute of Technology wireless access is available throughout the Science Building as well as the library and other spaces on campus.
Office space totalling 62 m2 is currently allocated exclusively to graduate students. The amount of space allocated to graduate students will increase as UOIT's graduate programs come online. It is expected that the majority of graduate students will have office space within the research laboratory of their respective supervisors. Faculty office space averages 13 m2 and faculty research space averages ~25 m2.
3.5 Financial Support of Graduate Students
3.5.1 Sources of Funding for Graduate Students
All students applying to the program in Applied Bioscience will be eligible for various forms of funding. Canadian students will be strongly encouraged to apply to provincial and federal granting agencies for graduate scholarships, and foreign students will be encouraged to apply to granting agencies in their own country.
Graduate Assistantships
Subject to the availability of funds, each student will be eligible for Graduate Assistantships that consist of a Teaching Assistantship and a Research Assistantship. Priority for Graduate Assistantships will be given to students in the first 20 months (5 semesters) of the program. The granting of a Graduate Assistantship to a student after this time would be treated on a case-by-case basis and would be subject to the availability of funds and the merit of the candidate. Students will automatically be considered for a Graduate Assistantship upon submission of their application to the program.
The funds from the Graduate Assistantships will be distributed in the following manner. The Teaching Assistantship will have an average load of 10 hours per week (maximum allowed by OCGS), with the duties consisting of conducting tutorial and/or laboratory sections and performing marking duties for undergraduate courses. The total number of hours per term will be 120. The total stipend as of 2004 is $8,400 per year ($4,200 per semester for 2 semesters). The bulk of the Teaching Assistantships will be available in the fall and winter semesters, with some being available in the spring/summer semesters.
The Research Assistantship, which is provided from the research grants of the student’s supervisor, will fund the student at an expected level of $7,600 per year. Each faculty member in the graduate program will have research funds available from NSERC Discovery Grants, other grants from government funding agencies, university start-up grants, and other funds from industrial partners. The duties of the student will be principally to conduct scholarly activities related to their thesis or research project, but these may also include assisting their supervisor on related research projects.
In summary, students obtaining a Graduate Assistantship will receive a minimum financial support of $16,000 per year ($5,333 per semester), provided from a combination of Teaching and Research Assistantships. This is comparable to the funding currently provided to Master’s students registered in similar programs at several other universities in Ontario.
Master of Science - Applied Bioscience 28 University of Ontario Institute of Technology
Anticipated Availability of Teaching Assistantships
As outlined above, we expect the proposed graduate program to have, at steady-state, approximately 38 graduate students. Of those, it is reasonable to expect that at least 35 will want to gain experience as teaching assistants, whether through the Graduate Assistantship program or as a complement to other sources of funding. Because these students cannot on average do more than 10 hours of teaching assistantship per week (as specified by OCGS), this workforce will account for at least 350 hours per week of tutorial time. For Fall 2005 and Winter 2006, undergraduate Biology and Chemistry courses given by the Faculty of Science will require 320 hours/week of tutorial and/or laboratory sessions given by teaching assistants. This will increase to 450 hours/week when courses for all 4 undergraduate years will be offered. Therefore, it is expected that graduate students in the program will be able to satisfy many of the tutorial hours needed in the Biological Science and Chemistry courses of the Faculty of Science.
UOIT Graduate Research Awards
We will offer several Graduate Research Awards to students who have strong research potential. The goal of these awards is to attract strong graduate students to the program and to provide a level of prestige for the recipient. At steady state, an amount of $114,000 (calculated as an average of $3000 per student registered in the program) will be available each year for Graduate Research Awards. The financial support of the students receiving the award may be supplemented by research and teaching assistantships. A competition based on academic excellence will determine the recipients and the value of the Graduate Research Awards in any given year.
International Student Tuition-fee Waivers
It is important to attract international students to the program in order to increase the visibility of the graduate program and of the University abroad. International students successfully completing the graduate program will be excellent ambassadors for UOIT in promoting the program and in promoting UOIT in general to potential students as well as to the academic community. Moreover, whether they continue their academic career or enter the job market in non-academic fields, they will enhance the reputation of UOIT. For these reasons, we think it is critical to attract international students. To this end, as part of the Graduate Research Award program, we are planning to offer partial tuition waivers to the strongest international students with excellent research potential, in order to offset the differential between the high international tuition fee and the domestic fee.
Director of Graduate Studies
A teaching relief of 1 course per year is required for the faculty member who will be Director of Graduate Studies for the program. The role of the Director will be to coordinate all the activities regarding the proposed graduate program. The director's duties will include: coordinating the Seminar Series on Applied Bioscience in which the graduate students will participate; coordinating the acceptance of students with the Registrar’s Office; and chairing committees such as those responsible for awarding the UOIT Graduate Research Awards and Graduate Research Assistantships. Additional Secretarial staff in the Faculty of Science will be hired in the future in order to assist with the clerical work required.
Master of Science - Applied Bioscience 29 University of Ontario Institute of Technology
3.5.2 Financial Counselling
The University and its Student Support Services shall make financial counselling available to students.
3.5.3 Annual Reporting
The Office of Graduate Programs, with the assistance of Student Services, shall issue an annual report on Student Financial Support to include the following:
• levels of student financial need; • student financial assistance provided, broken down by category and source (external/Faculty) of assistance; and • the debt levels carried by students upon graduation.
This report shall be submitted for information to the University's Academic Council.
Master of Science - Applied Bioscience 30 University of Ontario Institute of Technology
4. PROGRAM REGULATIONS AND COURSES
4.1 The intellectual development and the educational experience of the student
Major scientific discoveries often come at the intersection of scientific disciplines where researchers are less entrenched in established paradigms. In recognition of the potential of interdisciplinary research to solve problems encountered by today’s society, the UOIT academic units are not organized by departments but instead remain as cohesive faculties. This unique institutional organization facilitates researchers and students to establish research collaborations across disciplines, and it provides students with unique opportunities to gain experience with a variety of scientific techniques that may be amalgamated in their research efforts. UOIT is committed to promoting research and teaching excellence in the training of graduate students. Students in the Applied Bioscience Program (ABP) program will have an interdisciplinary advisory committee comprised of biologists, chemists, and health scientists which will guide them in becoming excellent scientists. The program also offers the opportunity for interested graduate students to participate in teaching and instructional development. The graduate research and educational opportunities provided in the ABP are designed to foster the highest quality of student intellectual development.
Students in the proposed program will be exposed to interdisciplinary research and will conduct their own research in NSERC- or CIHR-funded laboratories at UOIT. The Faculty of Science runs a Science Colloquium Series (SCS) that represents the integrated nature of UOIT by spanning topics that include mathematical science, physics, chemistry, and biology. This series is designed to promote interactions and discussions across scientific disciplines, and graduate students in the ABP will be required to attend and participate in the SCS sessions. Graduate courses have been designed to highlight the interdisciplinary focus of the ABP and are intended to expose students to a range of research fields within the applied bioscience network. These courses will also facilitate the development of skills that will assist students in becoming first-rate scientists, through the emphasis on the common themes of scientific writing and research ethics. Students will have access to regularly scheduled workshops in laboratory safety for chemical, biological and radioactive material. At UOIT, students will conduct research in laboratories equipped with state-of-the-art instruments in an intimate and interactive setting. A requirement of the ABP program is for students to present their work at regional, national, or international conferences, and they will be expected to ultimately publish at least one article in a peer-reviewed scientific journal based on their MSc work. Together, the interdisciplinary atmosphere of the ABP, the seminars and courses, and the state-of-the-art research facilities at UOIT will create a quality, student-centered, learning community.
UOIT Mission and Values
The mission and values of the University provide the foundation for all activities and are reflected in the plans for graduate students in the Faculty of Science. UOIT has developed operational and support processes to provide a fulfilling experience and a rewarding educational environment for graduate students.
We will provide for our graduate students a rigorous education and endeavour to instil in them the attitudes, values, and vision that will prepare them for a lifetime of continued learning and leadership in their chosen careers. In order for our students and faculty to engage in the scholarship of inquiry, discovery, and application, UOIT has made every effort to provide state- of-the-art learning resources, including the library, learning technologies, and laboratories. Details about these facilities are provided in Section 3.2. Master of Science - Applied Bioscience 31 University of Ontario Institute of Technology
As can be seen in Section 2, a team of well qualified faculty is available to facilitate the development of the students and for the ongoing monitoring of program quality and student progress. In addition, academic support staff and a range of student support services contribute to the operation of the department and provide service, guidance and support for graduate students.
Curriculum and Program Requirements
The learning outcomes for the MSc program are achieved through a combination of course work, supervised research, a research seminar, and a research thesis.
The combination of projects and/or research will be designed collaboratively between the student and an assigned faculty advisor/mentor. Each learner will have the opportunity to develop the prerequisites for specialized practice or advanced study in the fields of biomolecular science and/or environmental science and health.
Learning activities and materials in graduate courses will be carefully designed to ensure that learners are deliberately exposed to study, the majority of which is at, or informed by, the forefront of scientific theory and practice.
The courses have been designed to give students in depth learning in a specialized area of science, opportunity for advanced development of generic skills such as communication and teamwork, as well as participation in the scholarly activities of research, seminars, and presentations.
Throughout the curriculum, learning activities are planned, and student progress carefully monitored to ensure that safety, professional guidelines, and ethical responsibilities relevant to specific areas of advanced scientific study are modelled, developed, and evaluated.
Learning Community
The proposed program reflects UOIT’s commitment to providing innovative programs through excellence in teaching and learning, value-added research and “vibrant student life.” The physical design of the University environment provides many places for groups to meet and interact, for both academic and social purposes. The technological links available to students ensure that a network of communication and support among students and between students and University resources is established and strengthened during their years at UOIT. Facilities and personnel are available to support learning and development in all areas – academic, physical, social and emotional.
The student-centred philosophy of UOIT is designed to develop and continually enhance a strong sense of academic community in which students, faculty, support staff and administrators share ideas and experiences. Students in the MSc program will benefit from these learning partnerships.
Regularly scheduled scientific presentations, guest speakers, and research colloquia which are open to the University community are already a part of academic life at UOIT. With the implementation of graduate programs, this will be increased. In addition, the Faculty of Science plans to invite recognized experts and leading-edge researchers to present seminars and advise on student and faculty research. UOIT’s rich network of industry and academic contacts will provide access to exceptional researchers and professionals.
Master of Science - Applied Bioscience 32 University of Ontario Institute of Technology
Scholarly Activities
As can be seen in the basic outlines provided in Section 4.5, the courses, projects, presentations and thesis activities require students to undertake significant independent work and to organize and prepare reports and seminars. This facilitates the development of leadership, organization, communication, and professional presentation skills. These courses and seminars will be conducted in an environment which supports intellectual debate, allows for critique and constructive feedback, and encourages reflective practice.
All students in UOIT's graduate programs will be encouraged to attend professional conferences and educational sessions which may take place at UOIT or outside the university. MSc students will be encouraged to attend and participate in conferences and workshops relevant to their specialized area of interest. Financial support will be made available by their faculty supervisor. Students will be encouraged to present their thesis and project work at professional conferences and to other audiences through industry and academic networks.
4.2 Program regulations
4.2.1 Part-time studies
At this time, this program will only be available to registered full-time students.
4.2.2 Admission
Each applicant to the Master’s program in Applied Bioscience must meet the following requirements.
1. An honours undergraduate degree in Biology, Chemistry or Life or Health Sciences, with a minimum grade point average of a second class B average (3.0 on 4.3) in the last two years of their respective BSc (Hons) program.
2. To assist with the assessment of the application, the student should provide relevant course numbers, titles, a brief description of course content, textbooks used and/or chapters covered, and the grade received.
3. Admission depends on the availability of a Research Supervisor.
4. The student must submit an official transcript from all post-secondary institutions attended.
5. All non-English transcripts must be accompanied by an official translation. International students whose first language is other than English must meet the University's Language Requirements.
Formal academic policies and procedures for graduate programs, including those related to admission, are currently being developed by the Registrar's Office.
Master of Science - Applied Bioscience 33 University of Ontario Institute of Technology
Language Requirements
All applicants are required to give evidence of their oral and written proficiency in English. This requirement can be satisfied with one of the following criteria:
i) their mother tongue or first language is English ii) they have studied full-time for at least three years (or equivalent in part-time studies) in a secondary school or university where the language of instruction and examination was English iii) they have achieved the required proficiency on one of the tests in English language acceptable to the University of Ontario Institute of Technology (see below)
Recommended Scores – English Language Proficiency Tests (higher scores may be required) TOEFL (computer based) 220 TOEFL (paper based) 560 IELTS 7 MELAB 85 CAEL 70
Residence Requirements
Student’s who enroll in the ABP are expected to complete the program in 2 years. All program requirements must be completed on site at UOIT.
Distance Delivery
The program will not be delivered using a distance delivery model at the present time. In the future, it is expected that distance delivery of parts of the program will be used where appropriate for the subject matter.
Master of Science - Applied Bioscience 34 University of Ontario Institute of Technology
4.2.3 Degree Requirements
Course Requirements
Students must successfully complete three 3-credit courses, including APBS 5010G (Research in Applied Bioscience). In addition, they must prepare and orally defend a thesis, and complete APBS 5030G, Seminar in Applied Bioscience.
Core Courses (required)
APBS 5010G Research in Applied Bioscience (3 credits) APBS 5030G Seminar in Applied Bioscience APBS 5020G Thesis in Applied Bioscience
Elective Courses
Students will also select two of the following: APBS 53000G Advanced Topics in Biological Chemistry (3 credits) APBS 5100G Advanced Cell and Molecular Biology (3 credits) APBS 5200G Environmental Determinants of Health (3 credits)
4.2.4 Program Map
Program Map for the Master of Science in Applied Bioscience MSc – Year 1 Research in Applied Bioscience 2 elective courses Initiation of research program MSc – Year 2 Master thesis research Completion of Thesis in Applied Bioscience Seminar in Applied Bioscience
Section 4.5 provides detailed course descriptions and outlines.
4.2.5 Course Offerings and Frequency
All courses listed above will be offered every year.
4.2.6 Progress Reports
After completing the first year of their program and in each semester thereafter, MSc students must complete a progress report that outlines what they have done in the previous year or semester and their objectives for the following period. The progress report must be submitted to the student’s Advisory Committee. Permission to continue in the program will be based on a satisfactory report as determined by the student’s Advisory Committee.
Master of Science - Applied Bioscience 35 University of Ontario Institute of Technology
4.2.7 Thesis Evaluation Procedures
Each student will have an Advisory Committee; this Committee must be formed before the end of the student’s first semester of study. The Advisory Committee will normally consist of a Supervisor and two other faculty members in the Applied Bioscience program. Before the end of the first year of their program of study, students are required to provide to their Committee a written thesis proposal and to orally present their proposal to the Committee. The Committee must approve the proposed research program. Towards the end of their program, the student’s Advisory Committee must approve the commencement of thesis writing by the student. The final thesis will be evaluated by a Thesis Examination Committee and will be accompanied by an oral presentation; the student will receive a grade of either pass or fail. If the student receives a fail he/she will have one opportunity to improve the thesis either editorially, by additional experimentation, or by both if required; an additional examination may also be required.
The Thesis Examination Committee will normally consist of the following five (or more) members:
1) Dean of Research and Graduate studies (or delegate) who will also act as the committee chair 2) External examiner (or qualified delegate) 3) Internal examiner, from the Faculty of Science or Health Sciences, who did not serve on the student’s Advisory Committee 4) Supervisor(s) 5) One additional member of the Advisory Committee
4.3 Total Graduate Courses Listed and Level
APBS 5010G Research in Applied Bioscience. This is a required team-taught course designed to provide a foundation for the graduate program in Applied Bioscience. The course will provide students with current background knowledge and skills needed for research in Applied Bioscience and will expose students to current issues and problems that this area of research may target. The course will introduce such topics as principles of experimental design, data interpretation and analysis of results and how to present and communicate scientific information in both oral and written formats. Students will also learn about the grant and scholarship process and how to write a research proposal, and they will be introduced to such issues as Research Ethics and Intellectual Property. 3 cr, 2 lec. Prerequisite: None
APBS 5100G Advanced Cell and Molecular Biology. This will be a non-lecture based course where students and the faculty coordinator discuss current research in cell and molecular biology. The course will be a combination of group discussions and presentations. Each week a student will present either a research article or a synopsis of the current knowledge regarding a topic related to the course and possibly their own research interests. This will allow the students to apply basic concepts learned as undergraduate students to the current state of knowledge in cell and molecular biology. 3 cr, 2 lect. Prerequisite or Corequisite: APBS 5010G.
Master of Science - Applied Bioscience 36 University of Ontario Institute of Technology
APBS 5300G Advanced Topics in Biological Chemistry. This graduate course will explore a range of research topics at the intersection of chemistry and biology through examples selected from the current scientific literature. Topics to be covered include: protein engineering, enzymes, receptors, cofactors, enzymes for organic synthesis, biotransformations, catalytic properties of nucleic acids, bio-inorganic chemistry. 3 cr, 3 lect. Prerequisite or Corequisite: APBS 5010G
APBS 5200G Environmental Determinants of Health. This course will explore interactions between environment and human health. It will comprehensively address principles of environmental health, followed by specific issues regarding harmful environmental agents, and Canadian and global environmental health challenges. It will be designed to be delivered by an interdisciplinary faculty team potentially including members from the Faculties of Health Sciences, Science, Social Sciences and Engineering. It will attract health and non-health graduate students interested in the multi-factorial nature of environmental diseases. At the end of this course, students should have a broad understanding of how human health is contextually determined by our environment and be familiar with published seminal environmental health research. 3 cr, 3 lect. Prerequisite: APBS 5010G
APBS 5030G Seminar in Applied Bioscience. This course will require students to present a thorough overview of their thesis research, including relevant background material and research results and their interpretation. The presentation will be expected to be appropriate for an interdisciplinary audience in Science. This is a required, but non-credit course in the Applied Bioscience program. Seminars will be focused on specific research projects in Applied Bioscience. Student seminars will be regularly scheduled as needed. Prerequisite: good standing in the APBS program
Master of Science - Applied Bioscience 37 University of Ontario Institute of Technology
4.4 Graduate Course Descriptions and Outlines
Course Title: APBS 5010G Research in Applied Bioscience
Prerequisite: Enrolment in graduate program in Applied Bioscience at UOIT
Course Description:
This is a required team-taught course designed to provide a foundation for the graduate program in Applied Bioscience. The course will provide students with current background knowledge and skills needed for research in Applied Bioscience, and will also expose students to current issues and problems that this area of research may target. The course will introduce such topics as principles of experimental design, data interpretation and analysis of results and how to present and communicate scientific information in both oral and written formats. Students will also learn about the grant and scholarship process and how to write a research proposal, and they will be introduced to such issues as Research Ethics and Intellectual Property.
Topics that will be covered:
1) 21st Century Research in Applied Bioscience: differences and similarities between basic and applied biomedical research; hypothesis-driven research
2) The scientific method; principles of experimental design
3) Research ethics in Applied Bioscience
4) The granting system in Canada and the US
5) Basic grant writing skills
6) Scientific Writing: Communication of science in written formats, including preparation of scientific papers
7) Communication of science to the research community and the general public: verbal communication of science
8) Applied Bioscience research in Academia versus Industry
9) Intellectual property and patents in the context of Applied Bioscience
Master of Science - Applied Bioscience 38 University of Ontario Institute of Technology
Research in Applied Bioscience continued…
Learning Outcomes:
Students who complete this course have demonstrated the ability to:
1) describe the Applied Bioscience field and its importance to the lives of Canadians 2) have a good understanding of how research programs are started and maintained 3) understand the current issues and questions relevant in Research Ethics for Bioscience, including familiarity with the Tri-Council policy 4) understand the basic principles of communicating science to both the scientific community and to more general audiences 5) understand current issues in Academic and Industry based biomedical research
Delivery Mode: This is a one semester 3 credit course. The course will consist of one 2 hr lecture a week.
Rationale: The lectures, exercises and assignments will allow the students to achieve each of the above learning outcomes. The lectures are designed to provide a forum for students to learn about this rapidly changing field and to promote discussion. The lectures will be taught as a team by the UOIT Applied Bioscience faculty as well as guests from Industry and Academia.
Student Assessment: Two term papers 30% each, one oral presentation 20% and class participation 20%.
Faculty Qualification: PhD or equivalent
Representative Resources:
1) Science and technical writing: a manual of style. 2nd ed. New York : Routledge, 2001. 2) Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans 3) Human Pluripotent Stem Cell Research: Guidelines for CIHR-Funded Research 4) How to Prepare a Winning Proposal and other NSERC resources available for researchers preparing grant proposals at http://www.nserc.ca
Master of Science - Applied Bioscience 39 University of Ontario Institute of Technology
Course Title: APBS 5100G Advanced Cell and Molecular Biology
Prerequisite or Co-requisite: PBS 5010 Research in Applied Bioscience
Course Description: This will be a non-lecture based course where students and the faculty coordinator discuss current research in cell and molecular biology. The course will be a combination of group discussions and presentations. Each week a student will present either a research article or a synopsis of the current knowledge regarding a topic related to the course and possibly his/her own research interests. This will allow the students to apply basic concepts learned as an undergraduate student to the current state of knowledge in cell and molecular biology.
Topics that will be covered:
Topics in this course may vary according to research interests and current research events in cell and molecular biology, but would potentially include:
• Mechanisms of signal transduction and pharmacological effects • Host immune response to bacteria and parasitic infection • The cell biology of cancer and metastasis • Virus-host cell interactions • Cellular responses to toxic chemical and pollutant exposure • Human genomics, including advanced topics in gene inactivation/activation, methylation, gene interaction and interference
Learning Outcomes:
Students who successfully complete this course will have demonstrated the following abilities:
1. application of basic concepts to current knowledge 2. critical interpretation of research results and suggestion of future research avenues 3. comprehensible presentation of the current state of a particular research topic/problem 4. synthesis of current knowledge and building of hypotheses
Rationale: The discussion and presentation style format will expose students to an important part of research and discovery: the discussion of current knowledge. This will also provide a forum for active learning and encourage students to think beyond what is currently known in the area of cell and molecular biology.
Delivery Mode: This is a one semester 3 credit course. The course will consist of one 2 hr forum per week.
Student Assessment: Two term papers 40% each, oral presentation and class discussion 20%.
Faculty Qualifications: PhD or equivalent with expertise in cellular or molecular biology
Master of Science - Applied Bioscience 40 University of Ontario Institute of Technology
Advanced Cell and Molecular Biology continued…
Representative Resources: There would be no textbook required for this course. Instead, extensive use will be made of relevant literature in cell and molecular biology. Journals of focus would include Cell Journal of Biological Chemistry Journal of Immunology Journal of Bacteriology EMBO Nature Science Journal of Experimental Medicine Trends in Cell Biology Trends in Immunology Trends in Microbiology Trends in Pharmacological Science Nature Reviews Immunology Nature Reviews Molecular Cell Biology Aquatic Toxicology
Master of Science - Applied Bioscience 41 University of Ontario Institute of Technology
Course Title: APBS 5300G Advanced Topics in Biological Chemistry
Prerequisite or Co-requisite: APBS 5010G Research in Applied Bioscience
Course Description: This graduate course will explore a range of research topics at the intersection of chemistry and biology through examples selected from the current scientific literature.
Topics that will be covered:
Protein engineering (genetic and chemical methods of protein modification)
Enzymes (enzyme kinetics, enzyme inhibition, pharmaceutical application of enzyme inhibitors)
Receptors (G-protein coupled receptors and ion channels as targets for pharmaceuticals)
Cofactors (various cofactors of enzymes and their role in catalysis)
Enzymes for organic synthesis (the use of various classes of natural and engineered enzymes for the synthesis of organic molecules)
Biotransformations (the application of microorganisms in the production of chemical diversity)
Catalytic properties of nucleic acids
Bio-inorganic chemistry (the role of metal ions in biological processes, metal- containing drugs)
Learning Outcomes: Students who complete this course will have demonstrated the ability to:
1. discuss the current state of knowledge of research in biological chemistry. 2. explain various methods of generating modified proteins 3. distinguish between various types of enzyme inhibitions based on the analysis of enzyme kinetic data 4. describe the roles of cofactors in enzyme-catalyzed reactions 5. select an appropriate enzyme for desired transformation of organic molecules 6. explain how nucleic acids function as catalysts 7. define the roles of metals in biological systems 8. synthesize current research, present it in a comprehensible manner, and suggest future research avenues
Rationale: This course will expose students to the current state of knowledge in biological chemistry through provision of the necessary background and discussion of appropriate scientific articles. The latter will provide a basis for active learning and will inspire students to think beyond what is currently known about science.
Master of Science - Applied Bioscience 42 University of Ontario Institute of Technology
Advanced Topics in Biological Chemistry continued…
Delivery Mode: This is a one-semester 3 credit course with 3 hours of lecture weekly.
Student Assessment: Students will be evaluated based on assignments, one midterm and a comprehensive final examination.
Faculty Qualifications: PhD or equivalent with expertise in biochemistry or organic chemistry
Resources: No specific textbook for the course is required. Weekly readings will be selected from articles of peer-reviewed scientific journals, such as: Science Nature Proceedings of the National Academy of Science, USA Journal of the American Chemical Society Angewandte Chemie International Edition Chemistry & Biology Journal of Biological Chemistry Bioorganic & Medicinal Chemistry Bioorganic & Medicinal Chemistry Bioconjugate Chemistry Chembiochem: a European journal of chemical biology Biochemistry ACS Chemical Biology Molecular Pharmaceutics
Representative texts that will be made available are: Petsko, G. and Ringe, D. 2003. Protein Structure and Function. Blackwell. Mann, J.E. 2003. Chemical Aspects of Biosynthesis. Oxford University Press, Wong, C-H and Whitesides, G.M. 1995. Enzymes in Synthetic Organic Chemistry. Pergamon, Jencks, W.P. 1987 Catalysis in Chemistry and Enzymology. Dover.
Master of Science - Applied Bioscience 43 University of Ontario Institute of Technology
Course Title: APBS 5200G Environmental Determinants of Health
Prerequisite or Co-requisite: APBS 5010G Research in Applied Bioscience
Course Description: This course will explore interactions between environment and human health. It will comprehensively address principles of environmental health, followed by specific issues regarding harmful environmental agents, and Canadian and global environmental health challenges. It will be designed to be delivered by an interdisciplinary faculty team potentially including members from the Faculties of Health Sciences, Science, Social Sciences and Engineering. It will attract health and non-health graduate students interested in the multi- factorial nature of environmental diseases. At the end of this course, students should have a broad understanding of how human health is contextually determined by our environment and be familiar with published seminal environmental health research.
Topics that will be covered:
Principles of Environmental Health Ecology, environmental sciences and health Mechanisms (pathophysiology) of environmental disease
Agents of Environmental Disease Physical, chemical and biological agents (environmental agents, pollutants) Routes of exposure: water, air, soil, food (issues of food and water safety) Susceptible human systems & populations
Environmental Health Practice in Canada Canadian environment Canadian environmental epidemiology Canadian environmental health law Occupational health in Canada
Global issues in Environmental Health Exposure and risk assessment & communication Political and socioeconomic determinants in environmental health (Moira) Prevention of environmental diseases
Research Methodology in Environmental Health Best evidence in studies of environmental effects in health Limitations of environmental health research Benefits of quantitative and qualitative methodology
Master of Science - Applied Bioscience 44 University of Ontario Institute of Technology
Environmental Determinants of Health continued…
Learning Outcomes:
Students who complete this course have demonstrated the following:
1) an understanding of how human health is contextually determined by our environment. 2) an understanding of the agents and mechanism of environmental disease. 3) a critical assessment of local, national and global determinants of health 4) a familiarity with published seminal environmental health research and with research methodology in the field.
Rationale:
Graduate students in this course will be exposed to original research that links basic sciences, health and the environment. This course will be unique in allowing students to address the importance of environmental agents as determinants of health, understand the strengths and limitations of environmental health studies and foresee the relevance of basic research into health and communities.
Delivery Mode: This is a one semester 3 credit course. The course will consist of one 3hr forum per week.
Student Assessment: Term paper 25%, oral presentation 25%, class discussion 25%, Final exam 25%.
Faculty Qualifications: PhD or equivalent
Representative Resources: There would be no textbook required for this course. Instead, extensive use will be made of relevant literature in Environmental Science and Environmental Health. Journals of focus will be included.
Specialized Books: Blumenthal & Ruttenber, Introduction to Environmental Health, Springer Brooks et al., Environmental Medicine, Mosby Carson, Silent Spring, Houghton Mifflin Freedman, Environmental Science: A Canadian Perspective, Prentice Hall Schottenfeld & Fraumeni, Cancer Epidemiology and Prevention, Oxford
Specialized Journals: American Journal of Industrial Medicine Cancer Epidemiology, Biomarkers & Prevention Environmental Health Perspectives Environmental & Molecular Mutagenesis Environmental Toxicology
Master of Science - Applied Bioscience 45 University of Ontario Institute of Technology
Course Title: APBS 5030G Seminar in Applied Bioscience
Prerequisite: good standing in the APBS program
Course Description:
This course will require students to present thorough overview of their thesis research, including relevant background material and research results and their interpretation. The presentation will be expected to be appropriate for an interdisciplinary audience in Science. This is a required, but non-credit course in the Applied Bioscience program.
Topics that will be covered: These will be focused on specific research projects in Applied Bioscience.
Learning Outcomes: Students who complete this course have demonstrated the following knowledge:
1. effective communication skills in science 2. interpretation of research results and their presentation 3. the ability to answer questions about research 4. the ability to discuss the implications of a given research project
Rationale: This course is designed to give students better experience in communicating science, an essential skill in science today. This will also provide students with a forum for gaining feedback from their colleagues that can be incorporated into their final thesis.
Delivery Mode: Student seminars will be regularly scheduled as needed.
Student Assessment: Students will be evaluated based on the delivery of their seminar and on prior presentation of an outline. Feedback will be provided to the students by students and faculty through a standardized evaluation form.
Faculty Qualification: PhD or equivalent; faculty advisors will oversee the progress of their graduate students.
Master of Science - Applied Bioscience 46 University of Ontario Institute of Technology
5. OUTCOMES
5.1 Enrolment and Graduations
As this is an application for a new program, this section is not applicable.
5.2 Employment
Employment records of the graduates from the program will be maintained on an ongoing basis.
5.3 Publications
Publication records of the graduates from the program will be maintained on an ongoing basis.
5.4 Projected Graduate Intake and Enrolments
Table 5-1 shows the projected graduate student enrolment over the next seven years. As additional faculty are hired over the next few years, the planned enrolment in the program is expected to increase.
TABLE 5-1: PROJECTED INTAKE AND ENROLMENTS
Cumulative Enrolment Staff Requirements - Projected Technical Ratio of Full- YEAR Cumulative Cumulative Support time Full-time Part-time Full-time Part-time Teaching Students/ Faculty FTE Faculty FTE Assistants, Full-time etc. Faculty 2006 (Year 1) 13 0 14 0 0 1:1 2007 (Year 2) 27 0 15 0 0 1.8:1 2008 (Year 3) 33 0 18 0 0 1.8:1 2009 (Year 4) 37 0 19 0 0 1.9:1 2010 (Year 5) 38 0 19 0 0 2:1
Availability of Supervising Faculty and Funds:
At steady-state, we expect the program to have approximately 38 graduate students. This estimate is based on the expected number of faculty members who will participate in the program and on the availability of research funding for graduate students. Currently, the program has 10 faculty members, each with sufficient research funding to support at least two graduate students in the program. In addition to the research funds from start-up grants from UOIT, all members of the program either hold a NSERC Discovery Grant or have applied for one in Fall, 2004.
Master of Science - Applied Bioscience 47 University of Ontario Institute of Technology
In the next three years, the number of faculty participating in the program is expected to increase. In order to satisfy undergraduate teaching needs, new Faculty members will be hired for July 2006. New hires in Biology and Chemistry (approximately four) are expected to participate in the proposed graduate program, while new faculty members in the Faculty of Health Sciences may also participate in the graduate program, depending on their research interests.
We expect the graduate program to start in September 2006. Every year, 1 core course will be offered. In the initial two years of the program, 3 elective courses will be offered. We anticipate that additional elective courses will be developed in the next two years as new faculty join the program, and that elective offerings will be expanded to 5 elective courses. Thus, 1 new faculty position will be required in the initial year of the program, and an additional 0.5 new faculty positions will be needed in the third year of the program to cover the increase in teaching requirements. Therefore, at the start of the proposed graduate program, there will be at least 14 faculty members taking part in the program. We expect this number to increase to at least 19 in subsequent years, in view of the potential hiring. Thus, under the assumption that each faculty member would supervise on average approximately 2 graduate students at one time, we expect that at steady state, there will be approximately 38 students registered in the program.
Note that the year 2007 will see the first graduating class at the undergraduate level from the Faculty of Science. Many of these students will wish to pursue graduate studies, and the University should be prepared to receive these students throughout Ontario. The University will need to take this into account in developing their future hiring plans. A further increase in demand will also arise in 2007 due to the graduation of the double cohort students. Indeed, the number of strong applicants to the program may exceed our predictions so that the 19 faculty members expected in the program may not be sufficient to supervise and fund all of the incoming graduate students.
Master of Science - Applied Bioscience 48 University of Ontario Institute of Technology
Appendix A: Library Resources
Master of Science - Applied Bioscience 49 University of Ontario Institute of Technology
LIBRARY SUBMISSION TO ONTARIO COUNCIL OF GRADUATE STUDIES (OCGS) FOR THE MASTER OF SCIENCE IN APPLIED BIOSCIENCE
Compiled by: Carol Mittlestead, B.A., M.L.S., Associate Librarian
Introduction:
With respect to the University of Ontario Institute of Technology’s Master of Science in Applied Bioscience within the Faculty of Science, the following document discusses the Library in relation to the collection; the accessibility of resources and services; and research support, staffing, and partnerships. The collection includes both the traditional paper book or periodical, and the more nontraditional –but increasingly common-electronic index, book or journal database. Librarian recommended web sites are also a unique part of the collection in that they direct students and staff to valid academic sources. Resources also include an onsite reference assistance, the Library web page www.uoit.ca/library as a 24/7 portal, as well as interlibrary loan and document delivery. Our support staff is committed to teaching students, liaising with faculty, and connecting with government and corporate agencies.
Collections:
It is understood that the Library’s acquisition plan must be based on evolving pedagogical needs as determined by the academic schools. In close liaison with the Deans and Professors, subject specialist Librarians will define collection development strategies for the ongoing curriculum-based purchase of resources as well as for the evaluation and review of existing material.
Books:
The Library offers a developing but comprehensive collection. At present, there are approximately 70,000 volumes on the shelves. In mid-August, however, the Library took possession of its new building (described below) and this additional space will allow for the relatively quick expansion of the collection to 160,000 texts. Currently, there are approximately 7,500 volumes focusing on pure and applied science topics many of which relate directly to the Master of Applied Bioscience program. For example, books on genetics, viruses, toxicology, enzymes, proteins and environmental determinants are readily available. Sample titles include: • Genomics • Proteomics and Vaccines (Wiley) • The Microbial Models of Molecular Biology (Oxford University Press) • Plant Development and Biotechnology (CRC Press) • A Primer of Ecological Genetics (Sinauer Associates) • Infection and Immunity (Oxford University Press • Human Embryonic Stem Cells (Jones and Barlett) • Bioinformatics and Functional Genomics (Wiley). Similarly, the health science collection currently comprised of 6,500 volumes related to anatomy, physiology, pharmacology, occupational safety, and relevant government policies and laws, which will support Master of Applied Bioscience courses. As this is only the second year that UOIT has offered courses, most of the texts mentioned above are meant for those beginning their careers in science. It is realized that more specialized and academically focused books will be required for as the university develops. Master of Science - Applied Bioscience 50 University of Ontario Institute of Technology
Similarly, the Library also acknowledges UOIT faculty commitment to research and the supervision of graduate students. Consequently, additional books that address topics such as experimental design, interview and observation techniques, statistical gathering and interpretation, scientific and grant writing, are appearing in the collection. The resources required for the Research in Applied Bioscience course offered in the first semester of the Program has been noted.
The Library’s goal is to increase its holdings by 2,000 to 3,000 volumes per year for several successive years with a current projected cost of $400,000 to $450,000 per annum. Books are selected primarily (Faculty suggestions are most welcome) by Subject Specialist Librarians from noteworthy academic publishers (e.g. Wiley, CRC Press, Sage, Elsevier, Academic Press, Addison-Wesley, Kluwer, Springer-Verlag, Pearson Prentice Hall) and from Blackwell’s Book Services, an arrangement that allows for the simultaneous purchase of titles from a wide array of vendors.
The importance of specialty publishers for both print and online documents is also recognized. The Library will access and/or purchase as necessary standards, proceedings, and technical reports from key scientific organizations. Example sources include the Institute for National Measurement Standards-National Research Council Canada (INMS-NRC) and the Institute for Marine Biosciences-National Research Council Canada (IMB-NRC). Likewise, the importance of law especially as related to toxins is recognized; through databases such as CCOHS (Canadian Centre for Occupational Health and Safety) or regularly updated looseleaf services such as The Canadian Environmental Law Guide (Specialty Technical Publishers), the Library can provide practical ready reference to key statutes and regulations.
With over 13,000 titles (not included in the total above), e-books are an integral part of the UOIT library collection. Currently, Access Science, the Encyclopedia of Life Sciences, and the Merck Index are the e-book products most likely to interest Applied Bioscience students and faculty. Given UOIT’s commitment to the laptop university concept, the Library’s e-book collection is destined to grow.
Periodicals:
As of February 2005, it has been determined that the Library provides access to over 1,830 journals that specifically support the Applied Bioscience program. Periodicals considered here focus on topics such as biology, microbiology, botany, zoology, physiology, pathology, chemistry, pharmacology, agriculture, oceanography, and environmental science. There are also 1100 mathematics and 355 physics journals that may also prove to be useful references. Journals are available as traditional paper subscriptions, single electronic titles (e.g. Science, Nature, Nature Reviews (e.g. Immunology, Molecular Cell Biology, Microbiology, Cancer, Genetics)) or as one of several titles within an electronic database. Currently, the journal databases most pertinent to Applied Bioscience include: • BioOne • ACS (American Chemical Society) • RSC (Royal Society of Chemistry) • PubMed • Science Citation Index Expanded as part of ISI’s (Institute for Scientific Information) Web of Science • Academic Press • Elsevier (Science Direct • Springer-Verlag. Master of Science - Applied Bioscience 51 University of Ontario Institute of Technology
The last three products are consolidated within Scholars Portal, a search template that combines the electronic periodical holdings of several well-respected academic publishers. The databases that appear within Scholars Portal have been purchased through membership and participation in two university library consortia—OCUL (Ontario Council of University Libraries) and CRKN (Canadian Research Knowledge Network). The Library plans to purchase subscriptions to Biological Abstracts/BIOSIS Previews (Thomson ISI (Institute of Scientific Information)), Biological Sciences (Cambridge Scientific Abstracts (CSA) – a collection of approximately 25 databases addressing subtopics in biology e.g. amino acids, toxicology, ecology), and Environmental Science and Pollution Management (CSA). Depending on program direction, subscribing to Agricola may prove to be feasible as well.
Following the mandate of the University of Ontario Institute of Technology as a laptop university with “round the clock” accessibility to resources, whenever possible, the Library will purchase significant holdings to a journal in electronic format. It is, however, realized that paper copies may sometimes be essential, and must be purchased accordingly.
Internet:
While the prevalence and importance of the Internet is recognized, it is also realized that not all information on the Internet is of equal value and/or prominence, and that not all people have equal search skills. The Library, therefore, strives to make staff and students aware of quality web sites appropriate to their Program. Listings of recommended web sites are part of the Library Faculty Guides that are prepared with each UOIT program in mind. Posted on the Library web site www.uoit.ca/library , these Faculty Guides are discussed in detail under “Accessibility”. For example, relevant sites include: BioMed Central (open access collection of biology research articles), CMS Molecular Biology Resource (University of California), Canadian Society of Biochemistry, Molecular and Cellular Biology, and Canadian Federation of Biological Societies.
Accessibility:
The Building:
A new state-of-the-art, 73,000 square foot Library was opened in August 2004. The intent of the design is to create a print/electronic library that accommodates new and emerging technologies without sacrificing the personal warmth of a traditional library. The building offers various types of study and activity spaces to accommodate different learning styles and user needs. These spaces include:
Quiet public study spaces as well as a formal Reading Room, all within a “wireless” environment Collaborative learning spaces for groups of various sizes Common spaces and public service research workstations that facilitate intellectual interaction and engagement Electronic classrooms for regular ongoing educational sessions on library resources and research strategies Attractive and appealing display areas for art and library exhibitions Special needs adaptive technology equipment
Master of Science - Applied Bioscience 52 University of Ontario Institute of Technology
Staff, students and faculty have welcomed this new building with its seating for over 500 patrons and 150 public access workstations with Internet access. The grand opening was October 29, 2004.
ON CAMPUS REFERENCE ASSISTANCE:
Reference services are provided by professional librarians for 68 hours of the 89 hours (76.5%) per week that the Library is physically open. Librarians liaise with professors so classes specific to student research topics can be offered. Both staff and students are also welcome to make individual or small group appointments with Librarians.
Library Web Page:
The Library web page is available at www.uoit.ca/library and is accessible 24 hours a day, seven days a week. A Library e-mail address is provided as well as telephone information so individuals can leave messages at any time. In collaboration with other Ontario University Libraries, the Library is also currently investigating a web-based service such as the Virtual Reference Desk (www.lssi.com) which uses chat software to deliver reference service to users regardless of time and location. The Librarian can “push” pages to patrons so they can literally see both the steps involved and the results achieved with a given search. Consequently, this technology promises to be more effective than e-mail and telephone. Beginning with limited hours and an after-hours e-mail default, the ultimate goal is to make virtual reference a “round the clock” service.
General reference assistance is provided through Library web page sections that explain topics such as computer search techniques, article searching, internet evaluation, and bibliographic citation. Amongst the services outlined are circulation procedures, reserves, and interlibrary loan. What makes the UOIT Library web page truly unique is its Faculty Guides. Prepared with each program in mind for a particular Faculty, every Guide outlines and links to pertinent Electronic Databases and Indexes; provides sample listings with links to relevant journals along with subject headings for further investigation; highlights the Catalogue with suggestions from the Reference collection; describes and links to the most appropriate E-book databases; and offers Recommended Web Sites. These Guides are indeed resource portals.
Interlibrary Loan and Document Delivery:
Interlibrary Loan is available free of charge to students and faculty. Individuals have the option of making their requests online or in person. RACER (rapid access to collections by electronic requesting) is a VDX (Virtual Document Exchange) interlibrary loan system currently being implemented in OCUL member libraries. Students and faculty can search the catalogues of all Ontario university libraries and place immediate online requests for any available item. The system populates the request automatically with the bibliographic information from the record chosen. Here, only the patron name, i.d. number, and e-mail address are required for the online form. As part of OCUL and the IUTS (Inter University Transit System), the Library now receives book loans in a very reasonable amount of time, and Ariel, an electronic transmission system for periodical articles, allows journal requests to be filled within a few days.
Faculty and students from UOIT may also visit any of Ontario’s university libraries and may borrow books directly. Materials may be returned directly to the lending library or may be left at the UOIT Library where they will be returned to the appropriate lending library. Interlibrary
Master of Science - Applied Bioscience 53 University of Ontario Institute of Technology
Loans and document delivery are also available from other lending institutions (e.g. CISTI or libraries outside the province of Ontario) as required.
Research Support, Staffing and Partnerships:
The following strategies are established and/or being developed:
1. As described above, the Library as part of a newly formed institution (June 2002) has already made significant progress in terms of collection development, instruction and resource accessibility. Continued efforts will be made to improve and expand information services. As professors arrive on the UOIT campus, librarians are meeting with them to identify their teaching and research objectives.
2. A professionally qualified librarian (M.L.S.) with subject expertise in the sciences and health sciences joined the UOIT Library staff in August 2002. Given the anticipated appearance and evolution of more UOIT postgraduate programs, the hiring of a Graduate Studies Librarian will occur within the next two years.
3. The importance of liaising with the UOIT Centre for Academic Excellence and Innovation (CAEI), a facility where faculty are introduced and mentored in the use of instructional technology such as computerized teaching packages, presentation software, web development, and distance learning delivery is recognized. This would ensure that the Library’s resources, in digital format, are included amongst the links for courses developed within the Faculty of Science. A link to the Library Web Page Faculty Guides from each student’s “My WebCT” template is planned.
4. The Library will connect to local, national and global resources (e.g. Lakeridge Health Corporation, Canadian Biodiversity Information Network (CBIN)/Environment Canada) that both enhance student employment opportunities and that support high levels of applied scholarly research.
The Library is indeed preparing for the University of Ontario Institute of Technology’s initial postgraduate degree offerings, and lends its support to the resource and research needs of both faculty and students.
CM February 18, 2005
Master of Science - Applied Bioscience 54 University of Ontario Institute of Technology
Appendix B: Additional Information
1. Degree-Level Summary
2. Program Comparisons
3. Resource Renewal and Upgrading
4. Program Design and Credential Recognition
5. Applicant Acknowledgement and Agreement
Master of Science - Applied Bioscience 55 University of Ontario Institute of Technology
1. Degree Level Summary
UOIT is committed to providing high quality, challenging graduate programs which clearly meet and/or exceed the standards required for master’s degrees. The design of the MSc in Applied Bioscience has been guided by benchmarks described in the Postsecondary Education Quality Assessment Board Handbook for Applicants. The MSc is a research-oriented master’s degree, designed to build upon the knowledge and skills of well qualified applicants from relevant undergraduate programs.
The Faculty of Science intends to provide its graduate students with a rigorous education and to instill in them the skills, attitudes, values, and vision that will prepare them for a lifetime of continued research, learning and leadership in their chosen careers.
The program aims to provide students with a systematic understanding of the fundamental knowledge in the discipline of applied bioscience and in the program's designated fields. This base of knowledge will prepare them for advanced study and research in areas at the interface between chemistry and biology, competence in both of these subjects, the ability to tackle interdisciplinary problems and to work independently and successfully within collaborative networks. The knowledge and skills graduate students will acquire through their coursework and research activities will equip them with a wide array of both practical and conceptual skills that will prepare them for leadership roles in the life sciences.
In keeping with its mission and values, UOIT aims to provide its graduate students with programs of advanced study and research that are rigorous, challenging, and supportive. UOIT has made every effort to provide state-of-the-art learning facilities and resources including the library, learning technologies, and laboratories. Faculty members have applied for a CFI New-Opportunities grant for the formation of a Pharmaceutical Research Network. One of the main aims of this proposed Network is to provide current and future researchers at UOIT access to the most advanced technology that will facilitate the discovery of novel therapeutic approaches to treat human disease. Any new equipment and technology will provide UOIT, and graduate students in the program, with research capacity that is competitive both nationally and internationally.
The courses have been designed to give students in-depth knowledge in a specialized area of scientific study, opportunities for advanced development of generic skills such as communication and teamwork, and intensive involvement in the scholarly activities of research, seminars, and presentations. Throughout the curriculum, learning activities are planned and student progress monitored to ensure that safety, professional guidelines, and ethical responsibilities relevant to their areas of study and research are modelled, developed, and evaluated.
An interdisciplinary network of chemists, biologists and health scientists comprises the faculty team which will deliver and supervise the program in Applied Bioscience. The diverse group representing two Faculties - Science and Health Sciences - brings expertise in such areas as environmental toxicology, chemistry, physics, mathematics, computational science, microbiology and immunology, nutrition, mental and community health, pathology, molecular biology and cancer research. This provides a strong resource network for students wishing to pursue research in related areas of biochemistry, environmental sciences and health. The team will deliver the program in interesting and challenging ways to ensure that students acquire a critical awareness of current problems and/or new insights which is at, or informed by, the forefront of their academic discipline, field of study, or area of professional practice.
Master of Science - Applied Bioscience 56 University of Ontario Institute of Technology
Graduate students participating in this program will interact with peers and faculty with a variety of scientific backgrounds and research interests; this will further enrich their learning experiences.
The program's learning objectives will be achieved through coursework, a Science Colloquium Series, focused research training and the completion of a thesis. Course assignments will include written reports, oral presentations, review and critical analyses of professional literature and research.
Relevant Knowledge and Understanding
The UOIT environment provides a unique opportunity to provide an integrated educational experience in both biology and chemistry. Graduates are expected to advance their knowledge and understanding of essential facts, concepts, principles, and theories, as well as a critical awareness of current issues and research trends, in an area of complex scientific study. With this knowledge, they will be able to identify and analyze problems and to search for solutions in systematic and innovative ways.
Graduate students in the proposed program are required to attend and participate in a Science Colloquium Series (SCS) run by the Faculty of Science. This represents the integrated nature of UOIT by spanning topics that include mathematical science, physics, chemistry, and biology. This series is designed to promote interactions and discussions across scientific disciplines, thereby exposing students to a range of research fields both within and outside the applied bioscience network.
Exposure to breadth and depth of knowledge outside the field and/or discipline will encourage students to explore new insights and approaches as they engage in research projects and/or explore a variety of possible solutions to professional problems.
To ensure that graduates achieve the program's learning outcomes, the curriculum has been carefully designed to expose students to advanced theory, research and practice in a specialized area of science. As students engage in research activities, they are expected to demonstrate safe and competent use of technical and laboratory tools, equipment and techniques, including cutting-edge technology in biology and chemistry. The program is also designed to build upon transferable skills such as interpersonal relations, leadership and team building, communication, critical analysis and decision making, which have been developed in the students' previous undergraduate and work experiences.
Application
Through coursework, seminars and discussions, students will explore practical implications of applied bioscience research for both the scientific community and the general public. Under the guidance of a faculty expert, they will apply the concepts, principles and techniques they have learned to the investigation of a specific research problem. As they work through the their thesis project, students will be called upon to demonstrate their understanding of relevant theory and research related to their specialized field or area of study, their use of appropriate qualitative and quantitative methods of analysis to identify and evaluate a range of options and their skills in the conduct of research and management of projects.
Employers in the pharmaceutical and biotechnology industry, government and academia require graduates with a wide range of research skills and expertise in techniques used for Master of Science - Applied Bioscience 57 University of Ontario Institute of Technology biological study. The proposed program will provide students with training and hands-on experience with state-of-the-art analytical and biological instrumentation, thereby preparing them for employment in the field of Biomolecular Science.
Research in Environmental Science and Health will allow students to bridge laboratory-based discovery with community-based applications. Environmental sciences will be complemented by a health component that addresses any real or potential effects of environmental factors to health, informs and educates the community at large on these issues, and develops science and health researchers with strong awareness and skills to perform research connecting the environment and human health.
Students will acquire a systematic knowledge of inquiry and research methods, including qualitative and quantitative approaches of analysis. They will use technology models and state of the art laboratory equipment. They will be expected to demonstrate sound decision-making strategies to address problems.
In keeping with its vision and mission, UOIT is dedicated to the pursuit of inquiry, discovery and application through excellence in teaching and learning, value-added research and vibrant student life. Students in the Applied Bioscience Program will be expected to apply their knowledge, skills and discoveries to the creation of innovative solutions which will improve the lives of Canadians.
The Applied Bioscience program has been developed with local, regional and national interests in mind. The Region of Durham has a very diverse environment, with many unexplored environmental issues, offering ideal opportunities for research. Also, in this region there is a combination of industrial, rural, nuclear, socioeconomic and geographic conditions that are quite unique. Research in this region will benefit the community at large as well as the national and international research community.
Cognitive Skills
Problem solving, critical analysis, and synthesis are cognitive skills essential to success in any discipline. Graduate students in applied bioscience will be actively engaged in these processes throughout the program. Many opportunities will be provided for them to refine these cognitive skills, including: collaborative and independent learning activities; lab exercises; written critiques of theory and research; debates and discussions; and oral presentations that require justification of decisions. Activities and assignments will strengthen students’ abilities to critically analyze complex information they see, hear and read, to identify assumptions and implicit values, to gather appropriate data to inform and guide decision-making, to propose new hypotheses and interpretations, to create and assess a range of solutions, to predict risks and to evaluate methodologies and outcomes. Certain activities will require students to work in groups of various sizes; this will expose them to a variety of perspectives and require them to listen, assess and incorporate the ideas of others into the problem solving process. Collaborative activities will enable them to pose questions, devise and sustain arguments, and, most importantly, to be active participants in the learning process. While engaged in such interactive processes, they will learn from and contribute to the learning of others.
The Research in Applied Bioscience course will provide students with current background knowledge and skills needed for research in the discipline. It will familiarize them with current issues and problems that this area of research may target. This course and the students' subsequent independent research activities will hone their skills in the use of established tools
Master of Science - Applied Bioscience 58 University of Ontario Institute of Technology and techniques of research and inquiry, data interpretation and the analysis of results.
The Seminar in Applied Bioscience will require students to present, to an interdisciplinary audience, a thorough overview of their thesis research, including background, methodology, results and interpretation. Students in the audience will be expected to analyze and challenge what they hear; the presenters will be expected to present articulate and convincing responses.
Lifelong Learning
Students will develop skills necessary for clear communication and responsible teamwork and to professional attitudes and ethics, preparing them for modern work environments and encouraging them to engage in the pursuit of lifelong learning.
Stimulating seminars and colloquia, presentations by representatives from many areas of science, and intensive research activities will expose students to the complexities and challenges of scientific study. Master’s level science graduates must be prepared to work in complex and unpredictable environments, in different types of organizations and with a wide range of colleagues and clients. The program will support students as they develop positive attitudes and pro-active strategies to manage professional challenges such as change, ambiguity and limits to knowledge. Through their involvement in this interdisciplinary program, students will experience firsthand the value of diverse interpretations, methods, and disciplines in approaching and solving research problems.
Students will learn how to engage in advanced research by using print and electronic publications, including scholarly journals, books, and research websites for the most up-to-date information. They will recognize the need for independent and ongoing learning to maintain currency in a rapidly changing field and to further develop their professional skills. Graduates will have the advanced knowledge base and skill set needed to undertake further education to support and advance their careers.
Transferable Skills
The curriculum has been designed to emphasize the development of qualities and transferable skills which contribute to the students' success as independent learners and as team players. Throughout the program, graduate students will be involved in a variety of tasks that involve the demonstration of effective communication skills using oral, written, graphic and electronic formats. They will be expected to share information in ways which are suitable for both lay and specialist audiences. Students will participate in small and large group activities and hone their skills as both team members and leaders. The coursework in the program will require hours of research along with activities involving practical applications. The demanding workload will require students to organize their time and manage their projects efficiently in order to meet clearly defined standards of performance and expected deadlines.
UOIT is confident that the proposed program is sufficiently comprehensive and rigorous to meet the standards of a master’s level graduate degree program. It aims to develop in students the advanced knowledge base, enhanced technical, cognitive, and interpersonal skills as well as the positive attitudes that will enable them to experience personal, academic, and professional success during their graduate studies at UOIT and beyond.
Master of Science - Applied Bioscience 59 University of Ontario Institute of Technology
2. Program Comparisons
The Applicant has on file and available upon request the research undertaken to complete the following charts. The Applicant found that there are more than five similar or related existing programs offered at Ontario universities and that there are more than three similar or related existing programs offered at universities in other jurisdictions (outside Canada) which could have been included in this section.
Institution: University of Guelph
Program Name & Credential: MSc and PhD in genetics and in related areas of cell and molecular biology
Program Description: The University of Guelph offers both M. Sc. and Ph D programs in genetics and in related areas of cell and molecular biology. The minimum requirement for admission is a baccalaureate in an honours degree program, or the equivalent, from a recognized university. The applicant must have achieved an average standing of B- in the work of the last two undergraduate years.
In addition to a research thesis, three courses, including Research Topics, are normally required for the M. Sc. degree. Students must also take part in Seminars in Molecular Biology and Genetics and present a formal seminar on their research project at the end of their program.
Source: www.uoguelph.ca
Analysis of Similarities and Differences:
Similarities: • the U. of Guelph program and the UOIT program share an emphasis on cell and molecular biology • both programs require students to complete 3 courses and a research thesis and to take part in a seminar program Differences: • the UOIT program ties together chemistry and biology in the Biomolecular Science field, and also includes an option for students to specialize in the Environmental Sciences and Health field.
Master of Science - Applied Bioscience 60 University of Ontario Institute of Technology
Institution: Simon Fraser University
Program Name & Credential: M. Sc. and PhD in Molecular Biology and Biochemistry
Program Description: The Institute of Molecular Biology and Biochemistry at Simon Fraser University offers graduate programs which emphasize independent research and operate in a modern new laboratory building having excellent facilities. Major areas of research include developmental biology and genetics, using model invertebrate model systems and in structural and combinatorial biochemistry. Graduate degrees offered include M. Sc. and PhD in Molecular Biology and Biochemistry. Research Areas include: Molecular and Developmental Genetics; Molecular evolution and phylogeny; Signal transduction; Macromolecular recognition; Protein Engineering; Enzymology; Lipid and Protein Biophysics; Ribozymes; Combinatorial biochemistry and molecular biology(of peptides RNA and DNA)
Source: www.gradschools.com/listings/canada/bio_cell_canada.html
Analysis of Similarities and Differences:
Similarities: • the Simon Fraser program shares an emphasis on molecular biology and biochemistry with the Biomolecular Science field of the UOIT program. Differences: • the UOIT program has a stronger emphasis on chemistry • UOIT’s program includes a focus on Environmental Sciences and Health
Master of Science - Applied Bioscience 61 University of Ontario Institute of Technology
Institution: Queen's University
Program Name & Credential: M.Sc. and Ph.D. in Biology
Program Description: At Queen's University, the Department of Biology offers programs leading toward M.Sc. and Ph.D. degrees, with research in five broad areas of biology: Animal Physiology, Cell and Molecular Biology, P.E.A.R.L. (Paleoecological Environmental Assessment and Research Laboratory), Plant Science, and EEB (Ecology, Evolution and Behaviour). Master's programs consist of research and the preparation of a thesis. The program of studies and field of research is chosen in consultation with a supervisory committee. The course work will depend upon the experience and field of interest of the students. All M. Sc. students must complete two full graduate course equivalents with a minimum standing of 65% in each course. Courses from other institutions or faculties may sometimes be transferred for credit toward an M. Sc. but only after recommendation from the Graduate Studies Committee and approval by both Division I and the School of Graduate Studies. In certain instances, one-half graduate course credit may be obtained by taking an advanced undergraduate (full or half) course. In general, only 400-level undergraduate courses should be taken for graduate credit but if no suitable 400-level course is available, a 300-level can be taken, if approved. In all cases, students taking an undergraduate course for graduate credit must do additional work to bring the coursework up to graduate level. Students wishing to take one undergraduate course for graduate credit must request permission in writing from the Graduate Studies Committee, stating reasons for the course of choice and what extra work will be required to raise the level of coursework. Prior to graduating, candidates for the M. Sc. degree are expected to present their thesis work before one of the Departmental Journal Clubs or, in special cases, to present a seminar to the Department. Source: www.queensu.ca
Analysis of Similarities and Differences:
Similarities: • the Queen’s program shares an emphasis on cell and molecular biology, and has an environmental component as a separate field Differences: • The UOIT program contains two fields, while the Queen’s program contains 5 relatively diverse fields.
Master of Science - Applied Bioscience 62 University of Ontario Institute of Technology
Institution: University of Calgary
Program Name & Credential: M. Sc. and PhD degrees in Biochemistry and Molecular Biology
Program Description: At the University of Calgary, the Department of Biochemistry and Molecular Biology, Faculty of Medicine, offers graduate programs leading to the M. Sc. and PhD degrees in Biochemistry and Molecular Biology. Faculty members in the Department are affiliated with several Research Groups that include the Cancer Biology Research Group, Cardiovascular Research Group, Endocrine Research Group, Medical Genetics Research Group, Immunology Research Group, Joint Injury and Diseases Research Group, Molecular and Developmental Biology Research Group, and Smooth Muscle Research Group.
Source: www.gradschools.com/listings/canada/bio_cell_canada.html
Analysis of Similarities and Differences:
Similarities: • the U. of Calgary program and the UOIT program share a focus on biochemistry and molecular biology • both programs require students to complete 3 courses and a research thesis and to take part in a seminar program Differences: • the UOIT program also includes an emphasis on chemistry as well as biology in the Biomolecular Science field, and also includes an option for students to specialize in the Environmental Sciences and Health field.
Master of Science - Applied Bioscience 63 University of Ontario Institute of Technology
Institution: University of Utah
Program Name & Credential: M. Sc. and PhD degrees in Molecular Biology and Biological Chemistry
Program Description: The University of Utah offers graduate programs in both Molecular Biology and Biological Chemistry. These are each research areas that convey a sense of interdisciplinary investigation within the biological sciences. Graduate programs have historically been viewed as either “chemical” or “biological” depending on the background of the students and the techniques employed to investigate biological systems. Modern research in the biological sciences has increasingly blurred these traditional lines. Extensive collaboration among research groups at the University of Utah also provides a rich and diverse training environment for students, allowing for multidisciplinary projects that can easily span the traditional areas of genetics, cell biology, and biochemistry. The interdepartmental programs at the University of Utah are designed to support this overlap of training and methodology.
The research interests of the faculty in the two programs overlap extensively, and this is reflected by the fact that many faculty members participate in both programs. The first year curriculum is distinguished between the two programs by several core courses that reflect both the backgrounds of the students entering the programs, and the major focus of the faculty within the respective programs. While all first year program students take Protein/Nucleic Acid Biochemistry, the Molecular Biology students focus on a more “biological” curriculum including Genetics and Cell Biology while the Biological Chemistry students have a more “chemical” curriculum including Biophysical Chemistry, Protein Chemistry, and Structural Methods.
Source: http://www.bioscience.utah.edu/bc/bcProgram/bcProgram.html
Analysis of Similarities and Differences:
Similarities: • the U. of Utah and the UOIT program both emphasize interdisciplinary interactions and share a strong focus on molecular biology and biological chemistry; the “blurring of traditional lines” is a feature shared by both programs. • Both programs provide the opportunity for students to focus on either a more “biological” or a “chemical” curriculum through coursework. Differences: • the UOIT program differs mainly in that it includes a focus on Environmental Science and Health, and interactions of this field with that of Biomolecular Science are a key feature of the UOIT program.
Master of Science - Applied Bioscience 64 University of Ontario Institute of Technology
Institution: McMaster University
Program Name & Credential: Master of Science - Environment and Health
Program Description: The relationship of the environment to health is clearly one of the defining issues of the coming decades. McMaster University has responded to the need for more research and trained graduates in the field by adopting a Master of Science - Environment and Health program as one of the University's Strategic Areas, and by establishing the McMaster Institute for Environment and Health located within the School of Geography and Geology. The Master of Science program - Environment and Health allows students to focus on environmental health concerns. Typical areas of consideration include environment and health policy and development, spatial relationships and individual and community impacts.
Source: http://www.science.mcmaster.ca/geo/graduate/grad_prog.html
Analysis of Similarities and Differences:
Similarities: Both UOIT and McMaster programs both contain an environmental health focus.
Differences: While both programs focus on environmental health, UOIT’s Environmental Science and Health field has strong emphasis on biological outcomes of environmental health issues, and high degree of integration between Science and Health Sciences faculties. In contrast, the McMaster program focuses on health policy and areas of environmental health with an emphasis on geographical issues.
Master of Science - Applied Bioscience 65 University of Ontario Institute of Technology
Institution: University of Alberta
Program Name & Credential: MSc in Environmental Health Sciences
Program Description: The M. Sc. in Environmental Health Sciences degree at the University of Alberta concentrates on the knowledge and skills needed to investigate environmentally mediated human health concerns by evaluating the chain of causation arising from exposure to potentially hazardous agents through to adverse health outcome(s). Training emphasizes theories, concepts and practices of exposure assessment within the chain of causation.
Prior or concurrent training in environmental chemistry is required. The program provides a core of training in toxicology, exposure assessment, risk assessment, risk management and epidemiology. In addition, a selection of relevant optional courses throughout the University of Alberta is available.
Graduates of the degree will have an understanding of the background and domain of environmental health sciences; be able to design and perform independent environmental health research; understand the basis for development and implementation of criteria for protecting human health in terms of air, drinking water, soil exposure and food quality criteria and related risk management measures; be able to critically evaluate the environmental health literature and to work effectively with specialists in related disciplinary areas.
Students admitted to this program will be expected to have an advanced level course in environmental chemistry or will be required to take a course (PHS 510) as a co- requisite.
There are five required core courses: Fundamentals of Public Health, Environmental Contaminant Exposure Assessment, Environmental Risk Assessment and Management, Principles of Toxicology (or equivalent), Epidemiology Methods I. In addition, students are required to complete at least one graduate-level elective course, approved by the Department. Thesis Students will successfully complete and defend a thesis on a research topic in the program area, defined in consultation with the student’s supervisory committee. The scope and quality of the thesis should normally be appropriate to form the basis for a refereed journal publication. Source: www.phs.ualberta.ca/
Master of Science - Applied Bioscience 66 University of Ontario Institute of Technology
Analysis of Similarities and Differences (University of Alberta):
Similarities: • The UOIT and U of Alberta programs share a focus on environmental health science, the outcomes for human health and environmental factors. A toxicology component is included in both programs and both share an emphasis on chemistry. Differences: • The two programs differ in that the UOIT program includes the field of Biomolecular Science and emphasizes its integration with the field of Environmental Science and Health. • Students in the U of Alberta program are required to have an advanced level course in environmental chemistry as a pre or co-requisite; students in the UOIT program do not have this requirement, but can instead choose to have a more biological focus.
Master of Science - Applied Bioscience 67 University of Ontario Institute of Technology
Institution: Brock University
Program Name & Credential: M. Sc. in Biotechnology
Program Description: Brock University offers a M. Sc. in Biotechnology Program that is interdisciplinary in nature and is designed to provide a broad background in the cognate basic disciplines of biotechnology (biology and chemistry). Students with undergraduate degrees in chemistry or the biological sciences will be exposed to the breadth of biotechnology through mandatory participation in the seminar program, and will have the opportunity to focus on selected areas of biotechnology in other graduate courses. Each student will be assigned a supervisory committee composed of three members from at least two of the departments participating in the program. The student will meet with the committee at the start of their program, and on a regular basis, at minimum intervals of six months, for the duration of their program of study. Each meeting will involve the presentation by the student of a report on research objectives and progress, and discussion with the committee on the realization of these goals. In addition, each student will present one research level public seminar during their tenure in the program.
Candidates admitted to the program will require a minimum of one year of full-time study. The program must include BTEC 5F90; two 5(alpha)00 level half credits; two half credits (or one full credit) which may be either at the 4(alpha)00 or 5(alpha)00 level. One of the graduate half credits must be BTEC 5P95; one half credit may be taken from other 5(alpha) level courses offered by the Departments of Biological Sciences, Chemistry or Physics.
Additional credits may be required of candidates with insufficient preparation in their areas of research specialization, at the discretion of the supervisory committee. As part of BTEC 5F90, every MSc candidate must prepare and defend a thesis which demonstrates a capacity for independent work of acceptable scientific caliber.
Research Areas: Chemical Biotechnology - molecular design and synthesis; catalysis; biosynthesis and metabolism; structure and dynamics of biological macromolecules; Gene Biotechnology - regulation of gene expression; genetic engineering
Source: www.brocku.ca/webcal/2002/graduate/BTEC.html
Master of Science - Applied Bioscience 68 University of Ontario Institute of Technology
Analysis of Similarities and Differences (Brock University):
Similarities: • Both Brock University and UOIT programs emphasize the interdisciplinary nature of Biotechnology and aim for the integration of biology and chemistry. • Students with undergraduate backgrounds in either biology or chemistry are eligible for both programs • Students will participate in seminar programs that emphasize the interdisciplinary nature of research in this area Differences: • A key difference between the programs is the option for specialization in UOIT’s Environmental Science and Health field, and the emphasis on interactions between Molecular Bioscience and Environmental Science and Health
Master of Science - Applied Bioscience 69 University of Ontario Institute of Technology
3. Resource Renewal and Upgrading
Library Renewal and Upgrading
For Library Renewal and Upgrading, refer to Appendix A: Library Resources.
Computers and Computer Access
Further details regarding computer access are provided in Section 3.3 of the appraisal brief.
Classrooms and Physical Facilities
Capital plans are in place to develop two phases of building. Initial construction occurred on 115 acres immediately adjacent to Durham College. UOIT has purchased 385 acres to the north of this area to accommodate future growth.
The first University building, which was ready for occupancy in September 2003, contains classrooms, laboratories, and academic and staff offices. A 300-bed residence was also ready for the first class of UOIT students in September 2003.
The second phase of construction included one additional (200-bed) residence building, two additional academic buildings and a new library shared by UOIT and Durham College. This phase was completed in September 2004.
The initial core facilities for teaching and research at UOIT are housed in the three academic buildings. Together with the new campus library, these buildings overlook a campus commons. This precinct is the heart of the University and will be its central crossroads.
A key characteristic of each academic building is the provision of generous study and lounge spaces. These are complemented by a faculty lounge, Council room, small meeting rooms and student club offices. The lounge and study spaces are concentrated around a central skylit atrium which provides a point of orientation, gathering and connection for students and faculty. The buildings are designed to be highly flexible, adaptable to programs and teaching configurations yet unknown. Wired and wireless connections are provided through all dedicated and informal teaching spaces.
The new University library has been designed as the intellectual and social commons for this 21st century university. In particular, the library has two points of focus: the provision of access to electronic collections and resources and work and study space for 750 students. While the library will house a print collection of about 125,000 volume equivalents, with an emphasis on reference materials, it is in the provision of access through wired and wireless connection to electronic collections that the library will be distinguished. The building is designed on three floors with the connectivity and staff resources to fulfill this mission. Much attention has been devoted to the quality and variety of student space. Large study halls overlook the landscape commons and provide a variety of table, carrel and soft lounge seating. Many enclosed rooms are also provided for group study, seminar discussion and quiet work activities.
Construction of the new engineering building was started in early 2005. It is scheduled for completion for September 2005.
Master of Science - Applied Bioscience 70 University of Ontario Institute of Technology
Laboratories and Equipment
Faculty members will typically submit requests for capital equipment and instructional materials to their Dean one year in advance of the time in which it will be required. Such requests will be considered annually as part of the normal budgeting process for each Faculty and the University as a whole.
A Teaching Equipment Fund will be established to provide funds for laboratory and equipment purchases and renewals.
In addition, funds will be sought from donations to upgrade laboratories and equipment. It is the mandate of UOIT's Advancement Office to provide a permanent source of funds to enable the University to respond to new and growing needs that fall beyond its normal budgeting capability and to afford donors an opportunity to support UOIT in its strategic drive for growth, excellence and innovation.
In addition, certain specialized equipment may be purchased for use by faculty and graduate students through research grants awarded to individual faculty members.
Master of Science - Applied Bioscience 71 University of Ontario Institute of Technology
4. Program Design and Credential Recognition
UOIT is committed to providing high quality, challenging graduate programs which clearly meet and/or exceed the standards required for master’s degrees. The design of the MSc in Applied Bioscience has been guided by benchmarks described in the Postsecondary Education Quality Assessment Board Handbook for Applicants. (Program Degree Level, Benchmark 1, Handbook – Public, 7.1).
The MSc is a research-oriented master’s degree, designed to build upon the knowledge and skills of well qualified applicants from relevant undergraduate programs.
Research was conducted and documentation is on file to compare the breadth and rigour of the elements of this proposed graduate program to similar programs in Ontario and elsewhere. Details of program comparisons can be found in section 2 of this Appendix. Upon successful completion of the program, UOIT students will have achieved the degree level standard for the Master of Science Degree. This program has been deliberately designed to prepare students for further post-graduate study (see Section 1.4, page 10) but it is understood that applications for further study by graduates of the Applied Bioscience Program will be considered on a case-by-case basis by the admitting university.
Consultation
Academic details of the proposed program were submitted to UOIT's Curriculum and Program Review Committee for examination in January 2005. The proposal was then referred to the University's Academic Council and approved by that administrative body on March 15, 2005. These advisory and decision-making bodies supported the design of the Master of Science degree in Applied Bioscience and authorized the submission of this document to OCGS.
Dr. Ronald Stead, the President and Scientific Director of the Holburn Group of Companies and Associate Professor (Part time) at McMaster University was asked to review and comment on the proposed MSc in Applied Bioscience following its approval by the University's Academic Council. Dr. Stead's letter of support is provided on the page that follows.
Master of Science - Applied Bioscience 72 05/05/05 THU 10:02 FAX 905 623 6702 IIOLBURNBIOMEDICAL CORP 4ooz
HOLBURN BIOMEDICAL HQTBURN CORPORATION
May 5, 2005
Dr. William Smith Deanof Science University of Ontariolnstitute of Technology 2000Simcoe Street North Oshawa,ON LIHTK4
BY: tr'AX AFID COURIER
DearDr. Smith:
It wasa pleasureto reviewthe AppliedBioscience M.Sc. document that was recently approved by UOIT AcademicCouncil.
This is an innovative progmmme,focussing on two themes in Biomedical Science,covering both molecularand environmentalissues. Thesefoci are clearly areaswhich areundersubscribed, in termsof qualifiedresearchers in the worlqlace. In this context,the combinationof coursesthat you proposewill give graduatesof the M.Sc. programmesignificant enrployment opportunities and, more importantly,the skills to continueto learn and understandmechanisms underlying disease processes and how theseare affected by the environment. Of course,the graduateswill also be well qualified to enter doctoral programmes
When I visited your facilities recently,I was impressedby the state-qf-the-artlaboratories and the quality of equipmentavailable for researchwork. I was equally impressedby the enthusiasmof you and your colleagues;and the eagemessto expand your researchactivities. I think that an active graduate programmeis an essentialcomponent in further developinga vibrant sciencecore at UOIT.
I hope that in the future, scientists in our company may be able to participate in your graduate programmes.
in any way, pleasedo not hesitateto contactme.
Presidentand Scientifio Director The Holburn Groupof Companies AssociateProfessor (Part time) McMasterUniversity HonoraryProfessor Universify of Tuebingen
An independentmember of "The Holbum Group of Gohpanies" 200 Baseline Road East, Bowmanville,Ontario, Canada, LIG 142 Phone: +1 (905) 523-1484 Fax: +1 (905) 623-6702 [email protected] www.holburn.com University of Ontario Institute of Technology
5. Applicant Acknowledgement and Agreement Form
The Applicant Acknowledgement and Agreement form, signed by the President and Vice- Chancellor of the University, is included on the pages that follow.
Master of Science - Applied Bioscience 73
1.12 Noconsent shall take effect until the applicant pro- 2. Theapplicant hereby aErees to providethe Minister or videsconfirmation, in a writtenform approved by the thePostsecondary Education Quality Assessment Board with Minister,that the applicant understands and agrees to anyadditional material requined by the Minister or the complywith all ofthe terms and conditions attached boardto assessthe application. to the consent. 5. Theapplicant hereby confirms and wamants that: 1.13Shouldthe Minister grant a consent,the consent provided holderwill be required to ensurethat the followin8 3.1 Allinformation and representations bythe part statementappears on promotional and other materi- applicantas ofthis application, including informa- given als,in anymedia, that relate to thepnogram offered tion inthe 0rganization Review Submission and undertheconsent: the ProframQuality Assessment Submission, are true. Thisprogram is offeredunderthe writtenconsent of 3.2 Thisapplication was duly approved by the applicant's governing the Ministerof Training,Colleges and Universitiesfor bodyor byanother representative duly theperiod from (daylmonth/year) fo (day/month/year). authorizedto bind the applicant on Prospectivestudents are responsiblefor satisfying 15, themselvesthat theprlgram and the degreewill be Yn.ch Zoo5 appropriateto their needs(e.9., acceptable to poten' (dateof approval) tial employers,professional licensing bodies, or other at educationali nstitutionil. 't.14 0 N Theconsent holder has a positiveobli$ation under the 0:hawr , Post-secondaryEducation Choice and Excellence Act, (placeof approval) 2000,to notifythe Minister of Trainin$, Colle$es and Universitiespromptly if the consentholder has reason to believethat not all ofthe terms and conditions of a consentmay be met.
Dr. Gat Polo^sk Nameof authorizedrepresentative Prtsidt^t o.^d- V;cc- Ch o.^ctl lor Positi0nin applicant0rganizati0n University of Ontario Institute of Technology
VOLUME II: Curricula Vitae – Faculty Members
Professor
Barsby, Todd Bonetta, Dario Byrne, Carolyn Forrester, Sean Green-Johnson, Julia Holdway, Doug Jones-Taggart, Holly Naumkin, Fedor Paal, Krisztina Sanchez, Otto
-74- Barsby,T. Page 1 of 3
Program: Applied Bioscience May 2005
CURRUICULUM VITAE
Barsby, Todd, Assistant Professor, tenure-track
DEGREES
Ph.D., Chemistry, University of British Columbia, 2002 B.Sc (Hons.), Chemistry and Oceanography, University of British Columbia, 1996
EMPLOYMENT HISTORY
2004- Assistant Professor, Faculty of Science, University of Ontario Institute of Technology 2002-04 Postdoctoral associate, School of Biology, Georgia Institute of Technology 1997-02 Teaching Assistant, Department of Chemistry, University of British Columbia
GRADUATE SUPERVISIONS: N/A
GRADUATE COURSES: N/A
EXTERNAL RESEARCH FUNDING
Year Source Type* Amount/year Purpose 2005 American Society of Pharmacognosy O 5 000 (US) research 2005-2008 NSERC-Discovery G 22 000 research 2004-2006** NSERC-PDF G 40 000 postdoctoral fellowship 1999-01 NSERC-PGSB G 19 100 graduate fellowship 1998-99 Fletcher Challenge Limited I 15 000 graduate fellowship Research Fellowship
*Type- G: Government; I: Industry; O: Other **Declined due to Assistant Professor position at the University of Ontario Institute of Technology
INTERNAL RESEARCH FUNDING Year Source Amount Purpose 2005 Teaching Innovation Fund (UOIT) 5 000 teaching 2004-06 UOIT 150 000 research 2000-01 Gladys Estella Laird (UBC) 2 000 graduate fellowship Research Fellowship 2000-01 Faculty of Science Grant (UBC) 6 000 graduate fellowship Supplement Award
1999-00 UBC Graduate Fellowship * graduate fellowship 1999-00 Faculty of Science Grant (UBC) 6 000 graduate fellowship Supplement Award 1998-89 Gladys Estella Laird (UBC) 2 000 graduate fellowship Research Fellowship
Barsby,T. Page 2 of 3
*Declined due to existing funding
PUBLICATIONS
Life-time summary
-papers in referred journals………………………………………………………………..7 -abstracts and/or papers read ……………………………………………………………...1 -other (poster presentations) .……………………………………………………………. 6 -other (patents) …………………………….…………………………………………….. 2
Papers in referred journals
Barsby, T. and Kubanek J. Isolation and structure elucidation of feeding deterrent diterpenoids from the sea pansy Renilla reniformis. Journal of Natural Products. 2005, 68(4): 511-516.
Kicklighter, C.E.; Kubanek, J.; Barsby, T.; Hay, M.E. Palatability of Tropical Marine Worms: Alkylpyrrole Sulfamates from the Polychaete Cirriformia tentaculata as chemical defenses against consumers. Marine Ecology Progress Series, 2003, 263: 299-306.
Barsby, T.; Kicklighter, C.E.; Hay, M.E.; Sullards, M.C.; Kubanek, J. Defensive 2-Alkylpyrrole Sulfamates from the Marine Annelid Cirriformia tentaculata (Annelida: Polychaeta). Journal of Natural Products, 2003, 66(8): 1110-1112.
Barsby, T.; Linington, R.G.; Andersen, R.J. De Novo Biosynthesis by the Dendronotid Nudibranch, Melibe leonine. Chemoecology. 2002, 12(4): 199-202.
Barsby, T.; Kelly, M.T.; Andersen, R.J. Tupuseleiamides and Basiliskamides, New Acyldipeptides and Antifungal Polyketides Produced in Culture by a Bacillus laterosporus Isolate Obtained from a Tropical Marine Habitat. Journal of Natural Products, 2002, 65(10): 1447-145.
Barsby, T.; Kelly, M.T.; Gagne, S.G.; Andersen, R.J. Bogorol A Produced in Culture by a Marine Bacillus sp. Reveals a Novel Template for Cationic Peptide Antibiotics. Organic Letters, 2001, 3: 437-440.
Gerard, J.; Lloyd, R.; Barsby, T.; Haden, P.; Kelly, M.T.; Andersen, R.J. Massetolide A-H, Antimycobacterial Cyclic Depsipeptides Produced by Two Pseudomonads Isolated from Marine Habitats. Journal of Natural Products, 1997, 60: 223-229.
Abstracts and/or papers presented
Barsby, T.; Kubanek, J.; Hay, M.E. A Defense Against Whom? Investigating the Chemical Defense of the Sea Pansy Renilla reniformis with multiple predator types. International Society for Chemical Ecology, Ottawa, Canada, July 26, 2004.
Poster presentations
Barsby, T.; Kicklighter, C.E.; Hay, M.E.; Kubanek, J. The Story of One Worm’s Struggle to Survive: Cirriformia tentaculata and 2-Alkylpyrrole Sulfamates. 44th Annual Meeting of the American Society of Pharmocognosy, Chapel Hill, USA, July 2003. Barsby,T. Page 3 of 3
Barsby, T.; Mobley, K.; Kubanek, J. The Role of Briarane Diterpenes in the Chemical Ecology of the Sea Pansy, Renilla reniformis, 44th Annual Meeting of the American Society of Pharmocognosy, Chapel Hill, USA, July 2003.
Barsby, T.; Sorensen, D.; Kelly, M.T.; Andersen, R.J.; Bogorols: A New Family of Cationic Peptide Antibiotics Produced in Culture by a Marine Bacillus Sp. 10th International Symposium on Marine Natural Products, Nago, Japan, June 2001. 2nd International Peptide Symposium/17th American Peptide Symposium, San Diego, USA, June 2001.
Barsby, T.; Kelly, M.T.; Andersen, R.J. Bogorols, Novel Cationic Dodecapeptide Antimicrobial Metabolites Produced in a Culture by a Marine Bacillus Sp. 83rd Canadian Society for Chemistry Conference and Exhibition, Calgary, AB, May 2000.
Barsby, T.; Gerard, J.; Kelly, M.T.; Andersen, R.J. Basiliskamides A and B, Novel Polyketide Antimicrobial Metabolites Produced in a Culture by a Marine Bacillus Sp. 81st Canadian Society for Chemistry Conference and Exhibition, Whistler, BC, June 1998.
Patents
Barsby, T, Michael T. Kelly, Raymond J. Andersen. Peptide Antbiotics. US Patent # 6,784,283 (USPA #20020035239; Canadian PA # 2337923) Filed - Feb. 26, 2001; issued – Aug. 21, 2004.
Barsby, T, Michael T. Kelly, Raymond J. Andersen. Basiliskamides: Antifungal Microbial Metabolites. Canadian PA # 2273426 Filed - June 01, 1999. Examination – May, 2004.
Bonetta Page 1 of 2
CURRICULUM VITAE
Bonetta, Dario T., Assistant professor, tenure-track
DEGREES
PhD, Developmental Biology, University of Toronto, 2000 MSc, Molecular Biology, University of Toronto, 1995 BSc, Molecular Genetics and Biology, University of Toronto, 1992
EMPLOYMENT HISTORY
2005- Assistant professor, Faculty of Science, University of Ontario Institute of Technology 2003-04 Research scientist, Agriculture Canada, London 2000-02 Postdoctoral associate, Carnegie Institution, Stanford University 1992-00 Teaching assistant, Departments of Botany and Zoology, University of Toronto 1988-91 Lab technician, Hospital for Sick Children, Toronto
GRADUATE SUPERVISION: N/A
GRADUATE COURSES: N/A
EXTERNAL RESEARCH FUNDING Year Source Type Amount/year Purpose 2001-03 NSERC G $35,000 Postdoctoral fellowship
Type: G, government
INTERNAL RESEARCH FUNDING Year Source Amount/year Purpose
1999-01 Barbara McClintock $45,000 Postdoctoral fellowship Fellowship 1992-98 University of Toronto $3500 Graduate fellowship Open Fellowship
PUBLICATIONS
Lifetime summary -papers in refereed journals 6 -abstracts and/or papers read 2 -invited talks 3 -patents 1
Papers in refereed journals
Brady SM, Sarkar SF, Bonetta D and McCourt P (2003) The ABSCISIC ACID INSENSITIVE 3 (ABI3) gene is modulated by farnesylation and is involved in auxin signalling and lateral root development in Arabidopsis. Plant J 34, 67-75.
Somerville C and Bonetta, D. (2001) Plants as factories for technical materials. Plant Physiol 125,168- 71
Bonetta Page 2 of 2
Bonetta D, Bayliss P, Sage T and McCourt P (2000) A role for farnesylation in meristem organization in Arabidopsis. Planta 211,182-90.
Donnelly PM, Bonetta D, Tsukaya H, Dengler RE, Dengler NG (1999) Cell cycling and cell enlargement in developing leaves of Arabidopsis. Dev Biol 215, 407-419.
Bonetta D and McCourt P (1998) Genetic analysis of ABA signal transduction. Trends Plant Sci 6, 231- 235
Cutler S, Bonetta D, Ghassemian M, Cooney S and McCourt P (1996). A protein farnesyl transferase involved in ABA transduction in Arabidopsis.Science 273, 1239-1241
Abstracts and/or papers presented
Bonetta D, Facette M, Raab TK, and Somerville CR (2002) Genetic dissection of plant cell-wall biosynthesis. Biochem Soc Trans 30, 298-301.
Somerville C, Richmond T, Sedbrook J, Bonetta D, Facette M (2001) Genetic dissection of Arabidopsis cell wall biogenesis. American Chemical Society 221: U191.
Presentations
Genetic analysis of cell wall function. (2001) Biochemical Society Symposium on Glycobiology, York, U.K.
Farnesyltransferase function and function of NAP1 in cell division.(2000) John Innes Centre, Norwich, U.K.
Phenotypic characterization of vegetative defects of era1, an ABA supersensitive mutant. (1997) 8th International Conference on Arabidopsis Research, Madison, Wisconsin, USA.
Patent applications
Improved Stress Tolerance in Plants PPL97-06p Country USA submitted August 1, 1998
CURRICULUM VITAE
a) NAME: CAROLYN MARY BYRNE
Full Professor, Tenured b) DEGREES:
1. 1995 – 2000 PhD, Department of Family Studies and Applied Nutrition, University of Guelph, Guelph, Ontario, Canada, PhD Thesis: Parental Depression, Meaning and Agency in Family Relationships
2. 1980 – 1981 MHSc Programme, Health Care Practice, McMaster University, Hamilton, Ontario, Master of Health Sciences (MHSc)
3. 1975 – 1979 Clinical Behavioural Sciences Programme, McMaster University Clinical Behavioural Sciences Diploma
4. 1969 – 1971 School of Nursing, Hamilton Civic Hospital, Hamilton, Ontario Registered Nurse, 72_0315_1
c) EMPLOYMENT HISTORY:
2002 - present Dean & Professor of Health Sciences: University of Ontario Institute of Technology
2002 - present Clinical Professor: School of Nursing, McMaster University
1989 – 2002 Associate Professor: School of Nursing, McMaster University
1988 – 1992 Nurse Consultant: Mental Health Nursing, Community Mental Health Promotion Program, Hamilton-Wentworth Public Health (40% of time)
1987 Tenured McMaster University
1984 – 1989 Assistant Professor: School of Nursing, McMaster University
1981 - 1984 Lecturer: School of Nursing, McMaster University
1979 – 1980 Teaching Assistant: School of Nursing, McMaster University
1977 – 1979 Head Nurses: Community Social, Vocational, and Rehabilitation Programme (CSVR) Hamilton Psychiatric Hospital, Hamilton, Ontario
1975 – 1977 Team Leader: Outpatient Team - Social, Vocational, and Rehabilitation Programme Hamilton Psychiatric Hospital, Hamilton, Ontario
1973 – 1975 Family and Individual Therapist: Child and Family Centre, Chedoke Division, Chedoke-McMaster Hospitals, Hamilton, Ontario
1972 – 1973 Treatment Coordinator: Adolescent Unit, Hamilton Psychiatric Hospital
1971 – 1972 Staff Nurse: Adolescent Unit, Hamilton Psychiatric Hospital
CAROLYN BYRNE Page 2 d) ACADEMIC HONOURS:
2001 Health Promotion & Innovation Award of Excellence to research team on the study “When the Bough Breaks”, Canadian Institute for Child Health
1999 President’s Award for Educational Leadership, McMaster University
1980 – 1981 McMaster University - Graduate Scholarship
1980 – 1981 Hamilton Civic Hospitals - Rose C. Mosgrove Graduate Scholarship
e) SCHOLARLY AND PROFESSIONAL ACTIVITIES:
2005-present Advisory Council for the Provincial Centre of Excellence for Child and Youth Mental Health at CHEO
1999 – 2002 Associate Editor of Evidence Based Mental Health Journal
1998 – 1999 Visiting Professor, School of Nursing, University of Northumbria, Newcastle, England
f) GRADUATE SUPERVISIONS
Completed:
MHSc(N) 7 PhD 3
In Progress:
MHSc(N) 1
1. 2000 – 2005 Helen Kirkpatrick, PhD “Moving on from Homelessness”
2. 1998-2005 Kristin Cleverly, MHSc(N) – Psychiatric Disorder in Homeless Youth
3. 2001-2004 Larissa Volman, MHSc(N) – Uncovering sexual self of people with schizophrenia: patients’ perceptions of the impact of the illness upon their sexuality
4. 1999-2004 Deb Davidson, MHSc(N) Cultural diversity: Implications for Nursing education
5. 2000-2003 Iris Mujica, MHSc(N) – Living Through a Child’s Liver Transplantation Constructing Meaning as a parent
6. 1996-2000 Bronwyn Dunnachie, PhD - McNatty Department of Education, Canterbury University, New Zealand Wading Through a Pit of Mud, Adolescent’s Experience of Depression
7. 1998-2000 Carole Beauvais, MHSc(N) Completion of Treatment for Childhood Leukemia: An Exploration of the Meaning that others of Children with Acute Lymphocytic Leukemia attribute to the End of Their Childs Treatment 8. 1998-2000 Jennifer Dorresam, MHSc(N) “Cognitive Behavioural CAROLYN BYRNE Page 3
Therapy in Older Adult Depression”
9. 1997-1998 Peeter Poldre, PhD, Interdisciplinary Studies, OISE, University of Toronto. Collaboration in health care: Medical students’ perceptions, observations and suggestions
10. 1997-1999 Yvonne Ashford, MHSc(N), Parent and teacher disagreement in rating child behaviour
11. 2003 – present Tracey Chambers MHSc(N) – Nurses’ Knowledge and Attitudes Towards HIV/AIDS in Rural, KwaZulu-Natal, South Africa
g) GRADUATE COURSES
None in past 7 years
h) 1. EXTERNAL RESEARCH FUNDING
Year Source Type Amount /yr Purpose 2002 - 2003 Regional Homelessness Directorate $83,700 Research Principal Investigator (PI) C. Byrne 2001 - 2004 Trillium Foundation F $47,500 Research
National Child Benefit Re- O $15,000 investment Grant PI: N. Voorberg 1999 - Present AIDS Bureau, Ontario Ministry of G $553,560 Research Health and Long Term Care PI: G. Browne 2000 - 2001 Hamilton Community Foundation F $6,500 Research
The Hamilton Wentworth/Provincial G $45,000 Government Child Tax Benefits Program PI: C. Byrne 1999 - 2000 Immigrant Settlement and G $55,000. Research Adaptation Program PI: C. Byrne 1999 - 2000 Hamilton Community Foundation F $25,888 Research PI: M. Sanford 1998 - 1999 Hamilton Community Foundation F $15,000 Research PI: C. Byrne 1997 - 1999 Ontario Ministry of Health G $450,000 Research PI: G. Browne
G – Government, F – Foundation, C – Granting Councils, O - Other
CAROLYN BYRNE Page 4
2. INTERNAL RESEARCH FUNDING
Year Source Type Amount /yr Purpose 1999 - 2000 System-Linked O $3,000 Research Research Unit
i) PUBLICATIONS:
-scholarly books
Authored------0 Edited ------0
-chapters in books ------3
-papers in refereed journals------66
-papers in refereed conference proceedings------99
-major invited contributions------60
-abstracts and/or papers read------0
DETAILS OF PUBLICATIONS:
Chapters in books:
Byrne, C. (2003) Parental Agency and Mental Health: Proaction and Construction in Families with a Depressed Parent. IN L. Kuczynski (ed) Handbook of Dynamics in Parent-Child Relations. Sage Publications, (Chapter 12, pp. 229 – 243).
Byrne, C., and Hunsberger, M. (1994). Concepts of Illness: Stress, crisis and coping. In C.L. Betz, M. Hunsberger and S. Wright (Eds.), Family-Centered Nursing Care of Children 2nd ed. (Chapter 18), Philadelphia: W. B. Saunders.
Byrne, C., & Hunsberger, M. (1989). Concepts of illness: Stress, crisis and coping. In R. Foster, M. Hunsberger, & J. Anderson (Eds.), Family-centred nursing care of children (Chapter 23). Philadelphia: W.B. Saunders.
Papers in refereed journals
Byrne, C., Browne, G., Roberts, J., Gafni, A., Bell, B., Chalklin, L., (2004). Adolescent emotional/behavioural problems and risk behaviour in Ontario primary care: comorbidities and costs. Clinical Excellence for Nurse Practitioners, International Journal of NPACE, Vol. 8 (3)
Browne, G., Roberts, J., Gafni, A., Byrne, C., Kertyzia, J., Loney, P., (2004). Conceptualizing and validation the Human Services Integration Measure. International Journal of Integrated Care, May 2004, Vol. 4, ISSN 1568-4156, http://www.ijic.org/
Browne, G., Gafni, A., Roberts, J., Byrne, C., Majumdar, B., (2004). Effective/efficient mental health programs for school-age children: a synthesis of reviews. Social Science and Medicine, 58: 1367- 1384 CAROLYN BYRNE Page 5
Bell, B., Chalklin, L., Mills, M., Browne, G., Steiner, M., Roberts, J., Gafni, A., Byrne, C., Wallik, D., Kraemer, J., Webb, M., Jamieson, E., Whittaker, S., Dunn, E., (2004). Burden of dysthymia and comorbid illness in adults in a Canadian primary care setting: high rates of psychiatric illness in the offspring. Journal of Affective Disorders, 78, 73-80.
Sanford, M., Byrne, C., Williams, S., Atley, S., Ridley. T., Miller, J., Allin, H. (2003) A Pilot Study of a Parent Education Group for Families Affected by Depression. Canadian Journal of Psychiatry, Vol. 48 (2), 78-86.
Sword, W., Byrne, C., Drummond-Young, M., Harmer, M., Rush, J. (2002) Nursing alumni as student mentors: Nurturing professional growth. Nurse Education Today. 22, 427-432.
Browne, G., Steiner, M., Roberts, J., Gafni, A., Byrne, C., Dunn, E., Bell, B., Mills, M., Chalklin, L., Wallik, D., Kraemer, J. (2002) Sertraline and Interpersonal Psychotherapy for patients with dysthymic disorder in primary care: Six month comparison with longitudinal two year follow-up of effectiveness and cost. Journal of Affective Disorders 68(2-3): 317-330.
Markle-Reid, M., Browne, G., Roberts, J., Gafni, A., Byrne, C. (2002) The two year costs and effects of a public health nursing case management intervention on mood-disordered single parents on social assistance. Journal of Evaluation in Clinical Practise 8(1): 45-60.
Kirkpatrick, H., Landeen, J., Woodside, H., Byrne, C. (2001) How people with Schizophrenia build their hope. Journal of Psychosocial Nursing and Mental Health Services 39(1): 46-53.
Browne, G., Byrne, C., Roberts, J., Gafni, A., Whittaker, S. (2001) When the bough breaks: Provider-initiated comprehensive care is more effective and less expensive for sole support parents on social assistance. Social Science in Medicine. 53: 1697-1710
Browne, G., Roberts, J., Byrne, C., Gafni, A., Weir, R., Majumdar, B. (2001). The costs and effects of addressing the needs of vulnerable populations: Results of ten years of research. Canadian Journal of Nursing Research, 33(1): 65-76.
Byrne, C., Pape, B., Ivask, A., Kuczynski, L., Browne, G., Wittaker, S., Rae-Grant, N., Ashford, Y. (2001). Service needs of families where one parent has an affective illness; Implications for service education and policy. Canadian Journal of Community Mental Health, 20(1): 107-121.
Browne, G., Byrne, C., Gafni, A., Roberts, J. (2000). How can we reduce costs and get better outcomes in health care! Halton Social Planning Council & Volunteer Centre, Community Dispatch, 5(3): 1-4.
Procter, S., Watson, B., Byrne, C., Brenner, J., vanZwanenberg, T., Browne, G., Roberts, J., Gafni, A. The development of an applied whole-systems research-methodology in health and social service research: A Canadian and United Kingdom Collaboration. Critical Public Health, September 2000; 10(3): 331-342.
Watson, B., Procter, S., VanZwanenburg, T., Byrne, C., Browne, G., Roberts, J., Gafni, A. (2000). Interdisciplinary, Intersectoral and International Collaboration in Research. National Academics of Practice Forum, Issues in Interdisciplinary Care, 2000; 2(3):217-222.
Landeen, J., Pawlick, J., Woodside, H., Kirkpatrick, H., Byrne, C. (2000). Hope, Quality of Life and Symptom Severity in Individuals with Schizophrenia. Psychiatric Rehabilitation Journal, 23(4): 364- 369.
Weir, R., Browne, G., Byrne, C., Roberts, J., Gafni, A., Thompson, A., Walsh, M., McColl, L. (1999). The quick response initiative in the emergency department who benefits? Health Care Management Science 2, 137-148. CAROLYN BYRNE Page 6
Browne, G., Steiner, M., Roberts, J., Gafni, A., Byrne, C., Bell, B., Mills, M. (1999). Prevelence of dysthymic disorder. Primary Care Journal of Affective Disorders, 54, 303-308.
Watt, S., Browne, G., Roberts, J., Gafni, A., Byrne, C. (1999). Community Care for People with Chronic Conditions: An analysis of nine studies of health and social services utilization in Ontario. Milbank Quarterly, 77(3):363-392.
Steiner, M., Bell, B., Browne, G., Roberts, J., Gafni, A., Byrne, C., Dunn, E., Chalkin, L., Kraemer, J., Mills, M., Wallik, D. (1999). Brief Report: Prevelence of dysthymic disorder in primary care. Journal of Affective Disorders, 54: 303-308.
Byrne, C., Brown, B., Voorberg, N., Schofield, R., Browne, G., Gafni, A., Schuster, M., Watt, S., Roberts, J., Hoxby, H. (1999). Health Education or Empowerment Education with Individuals with a Serious Persistent Psychiatric Disability. Psychiatric Rehabilitation Journal, 22(4): 368-380.
Browne, G., Roberts, J., Gafni, A., Byrne, C., Weir, R., Majumdar, B. (1999). Community-based care is better. Canadian Health Care Management, 99(6): 69-70.
Browne, G., Byrne, C., Roberts, J., Gafni, A., Watt, S. (1999). Benefiting All the Beneficiaries of Social Assistance: The 2 - Year Effects and Expense of Subsidized Versus Non Subsidized Quality Child Care and Recreation. National Academies of Practice Forum, Issues in Interdisciplinary Care, 1(2): 109- 142.
Browne, G., Roberts, J., Gafni, A., Byrne, C., Weir, R., Majumdar, B., Watt, S. (1999). Economic Evaluations of Community-Based Care: Lessons from twelve studies in Ontario. Journal of Evaluation in Clinical Practice, 5(3): 109-119.
Byrne, C (1999). A Process of Dismantling Professional Boundaries: Nurses Facilitating Empowerment Groups. Issues in Mental Health Nursing, 19:55-71.
Papers in refereed conference proceedings
Cleverly K., Szatamari P., Semoqao D., Byrne C., (2004) The Effect of Street Life Experiences on Psychiatric Symptoms of Homeless Youth. Third International Conference on Urban Health, Boston, Mass. USA.
Browne, G., Byrne, C., (2004) Economic Evaluations of Community-Based Care: Lessons from 12 studies in Ontario. Canadian Association for Health Services & Policy Research, Montreal, Quebec.
Cleverley K., Semogas D., Byrne C., Szatmari P., (2003) An International comparison of psychiatric symptoms in inner city street youth. The Second International Conference on Urban Health, New York, New York.
Semogas D., Cleverley K., Thomas C.F., Sanford D., North T., Byrne C., (2003) Utilization of primary health care mental health care and social services by homeless street youth. The Second International Conference on Urban Health, New York, New York.
Cleverley K., Semogas D., Byrne C., Szatmari P., (2003) The Prevalence of Psychiatric Disorders in Canadian Inner City Street Youth. Department of Psychiatry Research Day, McMaster University, Hamilton, Ontario.
Clerverley K., Semogas D., Ford Thomas C., Byrne C., (2003) The relationship between readiness to change and mental health status amongst Canadian inner city homeless street youth. Challenging Old Paradigms Using the Transtheoretical Model, Buffalo, New York. CAROLYN BYRNE Page 7
Byrne, C., Belrose D. (2002) Using Research to Develop a Plan of Service, Education and Prevention in one AIDS Service Organization. Ontario HIV Treatment Network 5th Annual Research Day, Toronto.
Browne, G., Byrne, C. (2002) Investments in Comprehensive Programming: Services for Children and Single Parent Mothers on Welfare Pay for Themselves within One Year. 5th International Conference of the Child: Children and Poverty, Montreal.
Browne, G., Byrne, C., (2002) When the Bough Breaks. 5th International Conference of the Child: Children and Poverty, Montreal.
Byrne, C., Browne, G. (2002) Let’s talk: Team Approaches to Research Policy and Practice. Ready, Set, Go Conference, Ottawa
Byrne, C. Browne, G. (2001). Symposium on Integrated Services for Children, 8th Canadian Conference on International Child and Youth Health, Ottawa.
Voorberg, N., May, G., Byrne, C. (2001). Youth Net. What youth are telling us. Nursing Research Day, McMaster University. Hamilton, Ontario.
Byrne, C. (2001). The depressive experience, meaning making for couples. World Assembly for Mental Health. Vancouver, British Columbia.
Sanford, M., Byrne, C., Atley, S. (2001). Approaches to providing family psycho education for families affected by mood disorders. World Assembly for Mental Health. Vancouver, British Columbia.
Byrne, C. (2001). Promoting healthy child development through recreation. Ontario Municipal Social Services Association Learning Symposium. London, Ontario.
Byrne, C., Browne, G. (2000). Poverty, a recreation intervention for children to reduce risk. Beyond 2000, Healthy Tomorrows for Children and Youth Conference. Ottawa.
Browne, G., Byrne, C. (2000). When the bough breaks. Beyond 2000, Healthy Tomorrows for Children and Youth Conference. Ottawa. Byrne, C. 2000. Intersectoral and Integrated Services...more effective, less expensive. Creating the Future A New Vision for Children. Toronto.
Gafni, A., Roberts, J., Browne, G., Steiner, M., Byrne, C., Bell, B., Chalklin, L., Mills, M., Kraemer, J., Wallik, D. (1999). Economic Consequences of Combining Pharmacotherapy with Psychotherapy for Dysthymia in Primary Care. 2nd International Conference on the Synthesis Between Psychopharmacotherapy and Psychotherapy, Geneva, Switzerland.
G. Browne, Steiner, M., Roberts, J., Gafni, A., Byrne, C., Dunn, E., Bell, B., Mills, M., Chalkin, L., Wallik, D., Kraemer, J. (1999). The Two-Year Effects and Expense of Sertraline Versus Interpersonal Psychotherapy (IPT) Alone or Combined for People with Dysthymia in Primary Care. 2nd International Conference on the Synthesis Between Psychopharmacotherapy and Psychotherapy, Geneva, Switzerland.
Watson, B., Byrne, C. (1999). Family Identified Needs Regarding Service Provision in Managing Chronic Illness. The International Council of Nurses Centennial Conference, London, England.
Procter, S., Watson, W., Byrne, C. Browne, G. (1999). International Collaboration in Nursing Research. The International Council of Nurses Centennial Conference, London, England.
Ewart, B., Schuster, M., Browne, G., Byrne, C., Roberts, J., Gafni, A.. (1999). When the Bough Breaks: Provider-initiated Comprehensive Care is More Effective and Less Expensive for Sole Support CAROLYN BYRNE Page 8
Parents and Their Children on Social Assistance. 9th Canadian Social Policy Conference, Montreal, Quebec.
Procter, S., Rampogus, V., Byrne, C., Browne, G. (1999). Service Linked Research Units: Local and International Partnerships in Nursing Research. First Pan-Pacific Nursing Conference, Hong Kong, Hong Kong.
Underwood, J., Flynn Kingston, S., Browne, G., Byrne, C., Roberts, J., Gafni, A.. (1999). When the Bough Breaks: Provider-initiated Comprehensive Care is More Effective and Less Expensive for Sole Support Parents and Their Children on Social Assistance. Canadian Public Health Association Annual Conference, Winnipeg, Manitoba.
Byrne, C., Pape, B., Browne, G., Kuczynski, L. (1999). Parental Depression in Families, Consumer and Service Provider Insights. Ontario Association of Children’s Mental Health Centres, Toronto, Ontario.
Browne, G., Byrne, C., Roberts, J., Gafni, A., Watt, S., Ashford, Y., Jamieson, E., Wong, M. (1999). When the Bough Breaks: Provider-initiated Comprehensive Care is More Effective and Less Expensive for Sole Support Parents and Their Children on Social Assistance. Healthy People and Healthy Communities Conference, Toronto, Ontario.
Byrne, C., Kuczynski, L., Pape, B. (1999). Family Members Living with Depression. Mood Disorders of Ontario Annual Conference, Orillia, Ontario.
Browne, G., Byrne, C., Roberts, J., Gafni, A. (1999). Comprehensive Care for Sole Support Parents and Their Children. Royal College of Nursing of the United Kingdom Research Society Annual Nursing Research Conference, Keele Staffordshire, England.
Byrne, C., Browne, G., Roberts, J., Gafni, A. (1999). The Treatment of Dysthymic Disorder in Primary Care: The Effects and Expense. Royal College of Nursing of the United Kingdom Research Society Annual Nursing Research Conference, Keele Stafffordshire, England.
Procter, S., Watson, W., Byrne, C., Browne, G. (1999). What is Whole Systems Research and What it Can Do. Royal College of Nursing of the United Kingdom Research Society Annual Nursing Research Conference, Keele Staffordshire, England.
Major invited contributions:
Byrne, C., (2005) Postpartum Depression Among Adolescents “The Blues & Beyond” Le Gala Conference Centre, Whitby, Ontario
Byrne, C., (2004) Clinical Application of Research, Building Partnerships to Enhance Professional Development, Lakeridge Health Oshawa
Byrne, C., (2004) Professional Practice: What is it?, Professional Practice Planning Retreat Rouge Valley Health System, Toronto, Ontario
Byrne, C., (2004) Health Sciences at UOIT, Rouge Valley Health System
Byrne, C., (2004) Health Sciences at UOIT, Public Health Annual Division, Oshawa, Ontario
Byrne, C., (2004) Health Sciences at UOIT, RNAO local chapter meeting Rouge Valley, Ajax Pickering, Ontario
Byrne, C., Muirhead, B., Vogel, E., (2004) UOIT Nursing Programs: Laptops are a Fact of Life, Faculty Development Seminar, Grant MacEwan College, Edmonton, Alberta
CAROLYN BYRNE Page 9
Muirhead, B., Byrne, C., Vogel, E., (2004) Technological Integration at UOIT: The Full Story, Faculty Development Seminar, Grant MacEwan College, Edmonton, Alberta
Byrne, C., Muirhead, B., Vogel, E., (2004) UOIT Nursing Programs: Laptops are a Fact of Life, Faculty Development Seminar, Mount Royal College, Calgary, Alberta
Muirhead, B., Byrne, C., Vogel, E., (2004) Technological Integration at UOIT: The Full Story, Faculty Development Seminar, Mount Royal College, Calgary, Alberta
Byrne, C., Nursing Education and Research in the Future (2004), Keynote Speaker, Nursing Week, Lakeridge Health Corporation, Oshawa
Byrne, C., (2004), Measuring Organizational Capacity in AIDS Services Organizations C.L.E.A.R. Steering Committee, Toronto, Ontario
Browne, G., Byrne, C., (2004), A Crisis Occurring Among PHAs in Community-Based AIDS Organizations Treatment and Beyond Conference, Durham AIDS Committee, Oshawa, Ontario
Byrne, C., Browne, G., (2003) “Post Partum Mood Disorders, Royal Victoria Hospital, Barrie, Ontario.
Byrne, C., Sword W., (2003) Depression: Post Partum and Adolescent Depression, Nurse Practitioners Conference, Toronto, Ontario.
Byrne, C., (2003) The “I didn’t know it couldn’t be done so I went ahead and did it anyway school of action”. District Health Council Action Center Conference, Oshawa, Ontario
Byrne C., (2003) Health Resources: Roles for Volunteers, Annual General Meeting, Hospice Durham, Oshawa, Ontario.
Byrne C., (2003) The rewards, opportunities and challenges of Mental Health Nursing, Whitby Psychiatric Hospital, Whitby, Ontario.
Byrne C., (2003) Nursing, A Career Path for the Future. Getting our Heads Together Conference, Oshawa, Ontario.
Byrne C., (2003) Health & Human Resource Shortage, Durham Access to Care Annual General Meeting, Oshawa, Ontario.
Byrne, C., (2003) Reflection & Re-Invention, A Strategic Visioning Session – AIDS Bereavement Project of Ontario, Toronto, Ontario.
Byrne, C., (2003). When the Bough Breaks, Children and Arts Conference. Harbourfront, Toronto, Ontario.
Byrne, C. (2003). Health & Human Resource Shortage, Durham Access to Care Annual General Meeting.
Byrne, C. (2002). Depression and Parental Capacity, Parenting Conference, Sault Ste. Marie, Ontario.
Byrne, C. (2002). Postpartum Depression. Registered Nurses Association of Ontario Day Workshop. Peterborough, Ontario.
Byrne, C. (2002). Postpartum Depression. Registered Nurses Association of Ontario Day Workshop. Chatham, Ontario.
CAROLYN BYRNE Page 10
Byrne, C. (2002). Postpartum Depression. Registered Nurses Association of Ontario Day Workshop. Ottawa, Ontario.
Byrne, C. (2001). Postpartum Depression. Registered Nurses Association of Ontario Day Workshop. Kitchener, Ontario.
Byrne, C. (2001). The Mental Health Needs of Hamilton’s Youth. Annual General Meeting of CONTACT. Hamilton, Ontario.
Byrne, C. (2001). AIDS Service Organizations in Ontario: Organizational Capacity Building. Toronto, Ontario.
Byrne, C., Browne, G. (1999). When the Bough Breaks. Presented at Children’s Early Development Conference. Durham Region, Whitby, Ontario.
Byrne, C., Browne, G., Roberts, J., Gafni, A. (1999). The Positive Effects of Recreation for Children at Risk. Presented to the 50th Annual Meeting of the Catholic Children’s Aid Society of Hamilton.
Byrne, C., Browne, G., Roberts, J., Gafni, a. (1999). A Subsidized Recreation Program for Children of Single Parent Mothers on Welfare. YWCA National Conference, Guelph, Ontario.
SIGNATURE: ------
DATE: ------Curriculum Vitae
Sean G. Forrester, Assistant Professor, University of Ontario Institute of Technology, Tenure-track
DEGREES:
PhD, Parasitology, McGill University, Institute of Parasitology, 2003 MSc, Biology, Lakehead University, Department of Biology, 1997 BSc, Univ. College of Cape Breton, Department of Behavioral and Life Sciences, 1995
EMPLOYMENT HISTORY:
2004-present, Assistant Professor, School of Science, University of Ontario Institute of Technology 2002-2004, Post Doctoral Fellow, Department of Pathobiology, University of Pennsylvania 1997-2002, Graduate Student, Institute of Parasitology, McGill University 1995-1997, Graduate Student, Department of Biology, Lakehead University
ACADEMIC HONOURS:
NSERC Postdoctoral Fellowship (declined), 2004 T.W.M Cameron Award for excellence in Parasitology, McGill University, 2003 Dean’s Honours List, McGill University, 2003 Standard Life Dissertation Award (declined), McGill University, 2002 McGill Major Fellowship, McGill University, 2000 Murray Fallis Award/Best Parasitology Paper, Canadian Society of Zoologists, 2000 Meritorious Student Paper Award, American Society of Parasitologists, 2000 Helen Battle Award for Overall Best Poster, Canadian Society of Zoologists, 1999 Poster Award, Parasitology Section, Canadian Society of Zoologists, 1999 NSERC Postgraduate Scholarship, 1998 McGill Major Fellowship (declined), McGill University, 1998 Best Student Paper Award, American Society of Parasitologists, 1998 Murray Fallis Award/Best Parasitology Paper, Canadian Society of Zoologists, 1997 Lakehead University Entrance Scholarship, Lakehead University, 1995 University College of Cape Breton Entrance Scholarship, University College of Cape Breton, 1991
SCHOLARLY and PROFESSIONAL ACADEMIC ACTIVITIES:
Student Councilor, American Society of Parasitologists (2000-2001) Chair of the Student Advocacy Committee, American Society of Parasitologists (2000-01) Membership Committee, American Society of Parasitologists (2000-01) Member of the Research Ethics Board, UOIT (2004-present)
GRADUATE SUPERVISIONS: N/A
GRADUATE COURSES: N/A
EXTERNAL RESEARCH FUNDING:
Duration Source Amount Purpose 2005-2010 NSERC $35,180/year NSERC Discovery Grant 2004-2006 NSERC $ 80,000 Postdoctoral Fellowship* 1998-2000 NSERC $ 34,800 Postgraduate Scholarship *declined to accept position at UOIT
INTERNAL RESEARCH FUNDING.
Duration Source Amount Purpose 2004-2006 UOIT $ 150,000 Startup research grant
PUBLICATIONS: Lifetime summary
Type # Invited Book Chapter* 1 Papers in Refereed Journals 8 Paper in Refereed Conference Proceeding 1 Abstracts and/or Papers Read 7 Other: Poster Presentations 2 *submitted
Chapter in Book:
Forrester SG and Pearce EJ. Immunobiology of flatworm parasites. In: Parasitic Flatworms: Molecular Biology, Biochemistry, Immunology and Control. CIAB Publishers (submitted)
Papers in Refereed Journals:
1. Forrester SG, Warfel PW and Pearce EJ (2004) Tegument expression of a novel type II receptor serine/threonine kinase in Schistosoma mansoni. Molecular and Biochemical Parasitology 136: 149-156
2. Forrester SG, Beech RN and Prichard RK (2004) Agonist enhancement of macrocyclic lactone activity at a glutamate-gated chloride channel subunit from Haemonchus contortus. Biochemical Pharmacology 67: 1019-1024
3. Forrester SG, Prichard RK, Dent JA and Beech RN (2003) Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the anti-parasitic drug ivermectin. Molecular and Biochemical Parasitology 129(1):115-121
4. Forrester SG, Prichard RK and Beech RN (2002) A glutamate-gated chloride channel subunit from Haemonchus contortus: expression in a mammalian cell line, ligand-binding and modulation of anthelmintic binding by glutamate. Biochemical Pharmacology 63(6):1061-8
5. Forrester SG, Hamdan FF, Prichard RK and Beech RN (1999) Cloning, sequencing, and developmental expression levels of a novel glutamate-gated chloride channel homologue in the parasitic nematode Haemonchus contortus. Biochemical and Biophysical Research Communications 254: 529-534
6. Forrester SG and Lankester MW (1998) Over-winter survival of first-stage larvae of Parelaphostrongylus tenuis (Nematoda: Protostrongylidae). Canadian Journal of Zoology 76: 704-710
7. Forrester SG and Lankester MW (1997) Extracting Protostrongylus spp. larvae from bighorn sheep feces. Journal of Wildlife Diseases 33: 868-872
8. Forrester SG and Lankester MW (1997) Extracting protostrongylid nematode larvae from ungulate feces. Journal of Wildlife Diseases 33: 511-516
Paper in Referred Conference Proceedings
Prichard RK, Forrester SG, Njue A, Feng X, Liu J and Beech RN (2003). Receptor mechanisms of antiparasitics. Veterinary Pharmacology and Therapeutics 26 (supp): 29-31
Abstracts and/or Papers Read (Conference presentations)
1. Forrester SG, Beech RN and Prichard RK (2002) Genetic and biochemical characterization of a glutamate-gated chloride channel from Haemonchus contortus. Annual Meeting of the American Society of Parasitologists, Vancouver, BC
2. Beech RN, Forrester SG and Prichard RK (2001) Ion channels and anthelmintics in parasitic nematodes. Annual Meeting of the Canadian Society of Zoologists, Sudbury, ON (presented by Beech)
3. Forrester SG, Prichard RK and Beech RN (2000) Glutamate modulates ivermectin binding to a glutamate-gated chloride channel subunit from Haemonchus contortus. Annual Meeting of the American Society of Parasitologists, San Juan, Puerto Rico
4. Forrester SG, Prichard RK and Beech RN (2000) Glutamate modulates ivermectin binding to a glutamate-gated chloride channel subunit from Haemonchus contortus. Annual Meeting of the Canadian Society of Zoologists, St. Andrews, NB
5. Forrester SG, Blackhall WJ, Prichard RK and Beech RN (1998) Haemonchus contortus: Selection at a glutamate-gated chloride channel gene and a potential genetic marker for ivermectin resistance. Annual Meeting of the American Society of Parasitologists, Kona, Hawaii
6. Forrester SG and Lankester MW (1997) Over-winter survivorship of first-stage larvae of Parelaphostrongylus tenuis. Annual Meeting of the Canadian Society of Zoologists, London, ON
7. Forrester SG (1995) Analysis of Parelaphostrongylus tenuis in white-tailed deer in Cape Breton. Atlantic Universities Undergraduate Biology Conference, Cornerbrook, NFLD
POSTER PRESENTATIONS
1. Forrester SG, Blackhall WJ, Hamdan FF, Prichard RK and Beech RN (1999) A PCR based test for macrocyclic lactone resistance and characterization of an ivermectin receptor subunit from Haemonchus contortus. Annual Meeting of the World Association for the Advancement of Veterinary Parasitology, Copenhagen, Denmark
2. Forrester SG, Hamdan FF, Prichard RK and Beech RN (1999) Cloning and expression of a novel glutamate-gated chloride channel from the parasitic nematode Haemonchus contortus. Annual Meeting of the Canadian Society of Zoologists, Ottawa, ON
Sean G Forrester:______
Date:______Curriculum Vitae
Green-Johnson, Julia M. Assistant Professor, Faculty of Science (tenure-track) University of Ontario Institute of Technology
Degrees: Ph. D: Microbiology and Immunology, Queen's University, Kingston, ON, 1990. M. Sc: Microbiology, University of Saskatchewan, Saskatoon, SK. 1986. B. Sc. (Hon): Microbiology, University of Saskatchewan, Saskatoon, SK. 1983.
Employment History: • 2003-present time: Assistant Professor (tenure track), Faculty of Science, University of Ontario Institute of Technology • 2000-2003: Assistant Professor: (tenure track) School of Nutrition and Food Science/Dietetics, Acadia University • 2002 (July 1-Dec. 31st) Acting Director, School of Nutrition and Dietetics, Acadia University • 1994-2000: Assistant Professor (CLT) Dept. of Biology, Acadia University • 1990-1994: Postdoctoral fellow, Manitoba Institute of Cell Biology, University of Manitoba • Current Cross-appointments: Honorary Research Associate, Dept. of Biology, Acadia University. 2003-2005
Scholarly and Professional Academic Activities: • Invited speaker, Montreal International Symposium “Probiotics and Health: Applications in the Third Millennium”, Montreal, Oct. 28th -29th. Title of talk: Probiotics and the Immune System: Basic Aspects • Invited speaker, 3rd annual Institut Rosell Scientific Exchange Meeting, Mont Tremblant, PQ, Aug. 2002. Title of talk: “Modulation of Epithelial Cell Cytokine Production by Lactic Acid Bacteria” • Invited speaker, Institut Rosell Scientific Exchange Meeting, Aug. Hospital for Sick Children, Toronto, ON. July, 2000. Title of talk: “Effects of Lactic Acid Bacteria on Ab and Cytokine production: a comparison of strains” • Invited key researcher in the development of the Canadian Network for Research on Probiotic Bacteria and their Biofunctionality. (I was originally invited to act as Regional Director for the Maritime Region (2003), but declined when I relocated to UOIT). • Appointed an Honorary Research Associate at Acadia University (this allows me to supervise both B. Sc. Honours and Graduate students at Acadia University). • Invited member of the Canadian Research and Development Centre for Probiotics, coordinated by Dr. Gregor Reid, University of Western Ontario • Participant in the Local Organizing Committee for the 8th International Symposium for Microbial Ecology, Halifax, NS, 1998.
1 Graduate Supervisions: Completed: 1 M. Sc. (Acadia University), as Supervisor In Progress: 1 M. Sc. (Acadia University), as Supervisor
• Emily Turner-Brannen: Probiotics and Pathogens: interactions with epithelial cells and the effects on cytokine production. Registration: 2001. In progress. • Jennifer N. Zinn. Modulation of Tumour Necrosis Factor-α and Transforming Growth Factor-β by Norepinephrine in murine alveolar macrophages, murine splenocytes and transformed cell populations. 1996-1998.
Graduate Courses: • 1997-1998: Development and delivery of a graduate course, BIOL 5176 “Current Topics in Immunology” Dept. of Biology, Acadia University
• 2002. Participation in delivery of BIOL 5023: Current Topics in Biology. Dept. of Biology, Acadia University
External Research Funding in the past 7 years: Name(s) of Granting Bodies Principal Investigator Amount Year
Research Grants and Industrial Contracts currently held: • 2004-2009. NSERC Discovery Grant. “Probiotics and Fermented milks: immunomodulatory activity and fermentation effects on bioactivity”. $25,000 per annum. PI (and sole applicant) J. Green-Johnson. • 2004-2007. Ontario Ministry of Agriculture and Food New Directions Program: “Development of Fermented Soy Milks with Nutraceutical and Functional Food Potential” . $93,000 total. Operating Grant. PI: J. Green-Johnson; Co-applicants, Dr. C. Champagne (Agriculture and Agri- Food Canada) and Dr. N. Buckley (Canadian Space Agency. • 2004-2006. Nova Scotia Health Research Foundation Operating Grant: A proactive approach to health care in medical practices. $50,000/annum. PI: Rene Murphy (Acadia University), with R. Gould, J. Fowles, J. Green- Johnson, P. Campagna, S. MacDougall, I. Feltmate, M. Leiter, and B. Harris. • 2003-2008. Atlantic Innovation Fund. Nutritionally enhanced milk products for the Atlantic Dairy Industry. $2,776,237 total. Operating Grant. PI: Alan Fredeen (Nova Scotia Agricultural College), with K. Glover, C. Enright, L. MacLaren, C. Benchaar, J. Green-Johnson, P. Johnson-Green and C. Tranchant. • 2003-2004. Canadian Foundation for Dietetic Research. Sensory and Microbiological Quality and Vitamin C Content of Selected Pureed Foods for Elderly in Continuing Care Facilities. Operating Grant. $5,000 total. PI: Judy Lowe (Acadia University), with F. Russell, P. Johnson-Green and J. Green-Johnson.
2 Research Grants Applications currently submitted • 2004: Canadian Foundation for Dietetic Research (letter of intent approved Jan. 2005) The Interface Between Nutrition And Genes: Nutritional Genomics And Dietetic Professional Practice. PIs: E. Vogel and M. Ryan-Harshman. Co-applicants: H. Jones-Taggart, J. Green- Johnson, K. Anderson, Z. Austin, D. Castle.
• NSERC Crystal program, 2005. Virtual Mentoring, Professional Development and Computer Integration: Supporting Science, Mathematics and Technology Teachers. PI: R. van Ooostveen. Coapplicants: W.Hunter, L. Knaack, W. Smith, J. Cramer, R. Kay, W. Muirhead, E. Waller, H. Jones-Taggart, A. Chkrebtii, J. Green-Johnson, G. Lewis, I. Kletskin, V. Kapoustin.
Research Grants held previously (over the past 7 years): • 2002-2004. Nova Scotia Health Research Foundation Operating Grant: The effects of a home-based strength training program on independence and immune function of older Nova Scotians. $50,000/annum. With Rene Murphy (PI) and Shanthi Johnson (co-applicant). • 2002-2003. Dairy Farmers of Canada Nutrition Program/NSERC Collaborative Research Program. Operating Grant. “Novel Application for Fermented Milk Products: Modulation of Intestinal Eicosanoid Production.” $40,000 total. PI and sole applicant. • 2000-2001. Dairy Farmers of Canada Nutrition Program/NSERC Collaborative Research Program: Operating Grant. “Milk and the Immune System: New Applications for Fermented Milk Products”. $36,000 per annum. PI and sole applicant. • 1996-2000. NSERC operating grant. “Neuroimmune Interactions: Regulation of cytokine production by norepinephrine and neuropeptides”. $22,000 per annum • 1996-1998. Dairy Farmers of Canada, operating grant. “Probiotic bacteria: effects on immune function”. $20,000 per annum.
Industrial Contracts held previously (over the past 7 years): • 2003. Immunomodulatory actions of soy ferments. Institut Rosell, Lallemand Inc. $15,000. PI, J. Green-Johnson; co-investigator: J. Lowe (Acadia University). • 2002. Immunomodulatory evaluation of novel probiotics. Institut Rosell, Lallemand Inc. $15,000. • 2002. Bioavailability of iron-enriched yeast to a human enterocyte cell line (Caco-2). Institut Rosell, Lallemand Inc. $27.545 total. Co-investigator: P. Johnson-Green. • 2001-2002. Home-based strength training programs for older individuals. Eastern Kings Memorial Health Foundation. $14,160 total. (as Co- applicant; Principal Applicants, R. Murphy and S. Johnson)
3 • 2000-2001. Effects of Fermented and Non-Fermented Colostral Fractions on in vitro Measures of Immune Function. GalaGen Inc. $9,445 total. • 2001. Evaluation of the Immunomodulatory Ability and Intracellular Localization of Trace Elements in Mineral Enriched Yeast: Interactions with Human Intestinal Epithelial Cells. Institut Rosell, Lallemand Inc. $12,223 total. Co-investigator: P. Johnson-Green. • 2001. Evaluation of Novel Breads on the Immune System: Effects on Human Intestinal Cells. Institut Rosell, Lallemand Inc. $4,056 total. • 2000-2001. Evaluation of Novel Probiotic Bacteria on the Immune System: effects on Human Intestinal Cells. Institut Rosell, Lallemand Inc. $5,050 total. • 2000. Lactobacilli: Effects on the Immune Response. Institut Rosell, Lallemand Inc. $15,000 total. • 2000. Evaluation of the Effect of Mineral Enriched Yeast on the Immune System. Institut Rosell, Lallemand Inc. $2,025 total. • 2000. Evaluation of the Effects of Yeast Glucans on the Immune System. Institut Rosell, Lallemand Inc. $2,500 total. • 2000. Effects of Fermalac on the Immune Response. Institut Rosell, Lallemand Inc. $2,250 total. • 1999-2000. Lactobacilli and Health: Effects on the immune response. Institut Rosell, Lallemand Inc. $21,000 total.
Internal Research Funding in the past 7 years: • UOIT start-up funds: $100,000. 2003-2005. • UOIT matching funds: $50,000. 2004; awarded as matching funding for grant funds obtained while at UOIT. • AUFA Article 25.5 research grant (Acadia University). The sensory, nutritional and microbiological quality of pureed foods in continuing care facilities in western Nova Scotia. 2002-2003. $2,500. PI: Judy Lowe. Co- Investigators: P. Johnson-Green, F. Russell, & J. Green-Johnson. • AUFA Article 25.5 research grant, (Acadia University). 2001. Fungi, Air Quality and the Immune Response: Interactions of fungal spores with lung epithelial cells. $2,500. Co-investigator: P. Johnson-Green.
Publications:
1) Life-time summary: -Chapters in books……………………………………………………………….1 -Papers in refereed journals……………………………………………………17 -Papers in refereed conference proceedings………………………………….2 -Major invited contributions and/or technical reports………………………..10 -Abstracts…………………………………………………………………………38
2) Details for past 7 years:
Papers in refereed journals:
4
1. Fiander, A., Bradley, S., Johnson-Green, P., Green-Johnson, J. 2005. Effects of Lactic Acid Bacteria and Fermented Milks on Eicosanoid Production by Intestinal Epithelial Cells. Journal of Food Science, 70:M81-86.
2. J. M. Di Penta, J. M. Green-Johnson, and R. J. L. Murphy. 2004. Natural Killer Cells and Exercise Training in the Elderly: A Review. Canadian Journal of Applied Physiology, 29: 419-443.
3. Wallace, T., S. Bradley, N. Buckley and J. Green-Johnson. 2003. Interactions of Lactic Acid Bacteria with Human Intestinal Epithelial cells: effects on Cytokine Production. Journal of Food Protection. 66:466-472.
4. Easo, J., J.D. Measham, J. Munroe, and J. M. Green-Johnson. 2002. Immunostimulatory actions of lactobacilli: mitogenic induction of antibody production and proliferation by Lactobacillus bulgaricus and Lactobacillus acidophilus. Food and Agricultural Immunology. 14: 73-83.
5. Yehualaeshet T., R. O'Connor, J. Green-Johnson, S. Mai, R. Silverstein, J.E. Murphy-Ullrich, and N. Khalil. 1999. Activation of rat alveolar macrophage derived latent transforming growth factor beta-1 by plasmin requires interaction with thromobospondin-1 and its cell surface receptor, CD36. American Journal of Pathology. 155:841-851.
Papers Currently Under Review: 1. Green-Johnson, J., Smockum, L.E., and Murphy, R.J.L. Strength Training effects on salivary IgA production and functional abilities in retired individuals. Submitted to the Journal of Applied Physiology, July 2004.
2. Wood, C., Bradley, S., P. Johnson-Green and J. Green-Johnson. Lactic acid bacteria counteract LPS induced Interleukin-8 secretion by Intestinal Epithelial cells. Submitted to International Immunopharmacology, July 2003.
Papers in refereed conference proceedings:
1. Measham, J. and J. Green-Johnson. 2000. The immunomodulatory effects of Mineral Enriched Yeast in a murine system. pp 104-107 In: Probiotics and Health: The Intestinal Microflora. Montreal International Symposium Proceedings, edt. D. Roy. 2. J. M. Green-Johnson. 2005. Probiotics and the Immune System: Basic Aspects. Montreal International Probiotic Symposium Proceedings. In Press. Edt. D. Roy.
5 Technical reports:
1. Fiander, A., Lowe, J., Turner-Brannen, E. and J. Green-Johnson. Evaluation of Immunomodulatory Effects of Fermented Soy Powder Components. . Prepared for Institut Rosell, Lallemand, June 2003. Oct. 2002.
2. Bradley, S. and J. Green-Johnson. Evaluation of Immunomodulatory Effects of 5 Novel Probiotic Strains. Prepared for Institut Rosell, Lallemand. Oct. 2002.
3. Johnson-Green, P., Clace, D., Fiander, A., Bradley, S. and J. Green-Johnson. Bioavailability and immune modulating potential of iron-enriched yeast exposed to a human enterocyte cell line. Bioavailability of iron-enriched yeast to a human enterocyte cell line (Caco-2). Prepared for Institut Rosell, Lallemand, Nov. 2002.
4. Bradley, S., and J. Green-Johnson. Effects of Fermented and Non-Fermented Colostral Fractions on in vitro Measures of Immune Function. Prepared for GalaGen Inc. May 2001.
5. Johnson-Green, P. S. Bradley, and J. Green-Johnson. Evaluation of the Immunomodulatory Ability and Intracellular Localization of Trace Elements in Mineral Enriched Yeast: Interactions with Human Intestinal Epithelial Cells. Prepared for Institut Rosell (Lallemand Inc). Sept. 2001.
6. Bradley, S., and J. Green-Johnson. Evaluation of Novel Breads on the Immune System: Effects on Human Intestinal Cells. Prepared for Institut Rosell (Lallemand Inc.) July 2001.
7. Green-Johnson, J., Measham, J. and T. Wallace. Lactobacilli and Health: Effects on the Immune Response. Prepared for Institut Rosell (Lallemand Inc.). July 2000.
8. Measham, J.D. and J. Green-Johnson. Evaluation of the Effect of Mineral Enriched Yeast on the Immune System. Prepared for Institut Rosell (Lallemand Inc.) July 2000
9. Measham, J.D. and J. Green-Johnson. Evaluation of the Effects of Yeast Glucans on the Immune System. Prepared for Institut Rosell (Lallemand Inc.) May 2000.
10. Measham, J.D. and J. Green-Johnson. Effects of Fermalac on the Immune Response. Prepared for Institut Rosell (Lallemand Inc.) April 2000.
Abstracts:
1. Murphy, RJL, Green-Johnson, J., and J. Fowles. Effects of a Cross Country Running Season on Fitness and Immune Function in Women. To be presented
6 June 1st, 2005 at the 52nd Annual Meeting of the American College of Sports Medicine, Nashville, Tennessee. (abstract will be published in Medicine and Science in Sports and Exercise, 27:5 Supplement, 2005).
2. Green-Johnson, J., Fiander, A., Turner-Brannen, E., Buckley, N.D., Lowe, J., and P. Johnson-Green. 2004. Immunomodulatory potential of fermented milk and soy products: effects on intestinal epithelial cells. CIFST Annual Meeting, Guelph, ON.
3. Johnson-Green, P., Clace, D., Fiander, A. and J. Green-Johnson. 2004. Bioavailability and immunomodulatory potential of iron-enriched yeast. CIFST Annual Meeting, Guelph, ON.
4. Fiander, A., Johnson-Green, P., Buckley, N.D., Lowe, J. and Green- Johnson, J. Immunomodulation by Probiotic Lactic Acid Bacteria: impact on Epithelial Cell Eicosanoid Production. Experimental Biology 2004, Washington, DC (Abstract #4021).
5. Buckley, N.D., Turner-Brannen, E., Johnson-Green, P. and Green-Johnson, J. Coaggregation and Stimulation of Inflammatory Response by Microorganisms Associated with Denture Stomatitis. Experimental Biology 2004, Washington, DC. (Abstract # 4182).
6. Johnson-Green, P., Clace, D., Fiander, A. and Green-Johnson, J. Bioavailability and immunomodulatory effects of iron-enriched yeast to an enterocyte cell line. Experimental Biology 2004, Washington, DC. (Abstract #6514)
7. Clace, D., Green-Johnson, J., DiPenta, J., and Murphy, R.J.L. One year of resistance exercise training improves neutrophil activity in older individuals. Experimental Biology 2004, Washington, DC. (Abstract #1496)
8. DiPenta, J., Green-Johnson, J., Clace, D. and Murphy, R.J.L Participation in long-term moderate intensity resistance training increases natural killer cell activity and improves lipid profile in older adults. Experimental Biology 2004, Washington, DC. FASEB J 18(4): A751
9. Fiander, A., Lowe, J., Turner-Brannen, E., Buckley, N.D. and Green- Johnson, J. 2003. Evaluation of Immunomodulatory Potential of Lactobacillus delbrueckii ssp lactis strain Rosell 187 and of Fermented Soy Powder Components: Effects on epithelial cells. 4th Annual Rosell Scientific Exchange, Quebec City.
10. Amanda F, Johnson-Green, P. and Green-Johnson, J. 2003. Immunomodulatory Effects of Lactic Acid Bacteria and Fermented Milks on Eicosanoid Production by Intestinal Epithelial Cells. 4th Annual Rosell Scientific Exchange, Quebec City.
7
11. Smockum, L.E., Green-Johnson, J., Fowles, J.R., Kruisselbrink, L.D., Murphy, R.J.L. 2003. Effects of one-year of resistance training on immune function and functional abilities in retired individuals. Can. J. Appl. Physiol. S101-102. Canadian Society for Exercise Physiology Annual Meeting, Niagara-on- the-Lake, ON.
12. Smockum,, L.E., Caldwell, L.E., Fowles J.R., Johnson, S., Kruisselbrink, LD, Green-Johnson, J. and Murphy R.J.L. 2003. Functional benefits of home-based vs gym-based strength training for retired individuals. American College of Sports Medicine Conference (volume 35 #5) (San Francisco)
13. DiPenta, J.M., Green-Johnson, J., Fowles, J.R., Clace D. and R.J.L. Murphy. 2003. Long-Term Resistance Training Improves Natural Killer Cell Activity and Lipid Profile in Older Adults. Atlantic Provinces Exercise Sciences Annual Meeting. Antigonish, NS.
14. Smockum, L.E., Green-Johnson, J., Caldwell, L.E., Fowles, J.R., Murphy, R.J.L. 2003. Home-based vs gym-based strength training effects on immune function and functional abilities in retired individuals. Atlantic Provinces Exercise Sciences Annual Meeting. Antigonish, NS.
15. Bradley, S., Wood, C., Johnson-Green, P., Measham, J. and Green- Johnson, J. 2002. Modulation of Epithelial Cell Cytokine Production by Lactic Acid Bacteria. Montreal International Symposium on probiotics and Health: Biofunctional perspectives.
16. Bradley, S ., Wood, C., Johnson-Green, P. and Green-Johnson, J. 2002. Interactions of Lactic Acid Bacteria with Epithelial Cells: Modulation of Cytokine Production. Institut Rosell Scientific Exchange Meeting, Mont Tremblant, Quebec.
17. Wallace, T.D., J.D. Measham, T. A. Tompkins and J. M. Green-Johnson. 2000. Induction of Interleukin-6 and Tumour Necrosis Factor production by Lactic Acid Bacteria. Annual meeting of the American Association of Immunologists, Seattle, Washington.
18. Measham, J.and J. Green-Johnson. 2000. The Immunomodulatory effects of Selenium, as a Component of Mineral Enriched Yeast, in a murine system. International symposium on Probiotics and Health: the Intestinal Microflora. Montreal QC.
19. Wallace, T.D., T. A. Tompkins and J. M. Green-Johnson. 2000. Effects of Lactic Acid Bacteria on cytokine production by a human intestinal epithelial cell line. Year 2000 Danone Symposium (New York).
8 20. A.A. Babcock, J.D. Measham, J.M. Green-Johnson. 1999. Casein-Derived Opioid Peptides and Lactobacilli: Effects on Cell Proliferation and Antibody Production. 49th annual meeting of the Canadian Society of Microbiologists, Montreal, Quebec.
21. J. D. Measham, A. A. Babcock and J. M. Green-Johnson. 1999. Immunomodulatory Effects of Different Lactobacillus spp. on Proliferation and Cytokine Production by Murine Splenocyte Fractions and Cell Lines. 49th annual meeting of the Canadian Society of Microbiologists, Montreal, Quebec.
22. J. D. Measham and J. M. Green-Johnson. 1998. Varied immunomodulatory effects of different Lactobacillus spp. on cytokine production by murine splenocytes, murine macrophages, and macrophage cell lines. 8th International Symposium for Microbial Ecology, Halifax, N.S., August, 1998.
23. Easo, J.G., J.D. Measham, and J. Green-Johnson. 1997. Possible mitogenic effects of Lactobacillus spp. On murine spleen cells and murine B, T and macrophage cell lines. 47th annual meeting of the Canadian Society of Microbiologists, Quebec.
Signature:
Date:
9
CURRICULUM-VITAE
Dr Douglas A. Holdway Tier 1 Canada Research Chair in Aquatic Toxicology, Full Professor of Ecotoxicology, University of Ontario Institute of Technology, foundation faculty, tenured, Employee No. 100246238
Degrees:
PhD, Marine Biology University of Guelph, Department of Zoology, Canada, 1983 MSc, Aquatic Toxicology University of Guelph, Department of Zoology, Canada, 1978 Bsc (Hon.), Marine Biology University of Guelph, Department of Zoology, Canada, 1976
Employment History:
2004-present Tier 1 Canada Research Chair in Aquatic Toxicology, Full Professor of Ecotoxicology, (tenured) Faculty of Science, University of Ontario Institute of Technology, Ontario
2003-2004 Professor of Ecotoxicology (tenured) School of Science, University of Ontario Institute of Technology, Ontario
2002-2003 Professor and Visiting Research Associate (term), Research & Development, Department of Biology, University of Prince Edward Island, Charlottetown, PEI
1996-2002 Professor of Ecotoxicology (tenured), Head, Oil Spill Research Group Department of Biotechnology and Environmental Biology (formerly ABBT), RMIT-University, Melbourne. Australia.
1993-1995 Associate Professor of Environmental Biology and Ecotoxicology (tenured), Head, Oil Spill Research Group Department of Applied Biology and Biotechnology, RMIT- University, Melbourne, Australia.
1993-1995 Associate Professor of Environmental Toxicology (tenured), Chief Environmental Toxicologist. Key Centre for Applied and Nutritional Toxicology, RMIT, Melbourne, Australia
1989-1993 Senior Research Fellow (term)- Chief Environmental Toxicologist Key Centre for Applied and Nutritional Toxicology, RMIT, Melbourne, Australia
1988 - 1989 Senior Research Scientist (permanent), Head - Aquatic Toxicology Section, Alligator Rivers Region Research Institute, Office of the Supervising Scientist, Jabiru East, N.T., Australia
UOIT CV- Dr D. A. Holdway 07/28/04 1986 - 1988 Research Scientist (permanent), Head - Aquatic Toxicology Section, Alligator Rivers Region Research Institute, Office of the Supervising Scientist, Jabiru, N.T. Australia
1985 - 1986 Canadian Government Laboratory Visiting Fellow - Acid Rain Chemistry, National Water Research Institute, Canada Centre for Inland Waters,, Burlington, Ontario, Canada
1983 - 1985 National Research Council of Canada (NRC) Funded Research Associate in Aquatic Toxicology, Department of Biology, University of Waterloo, Ontario, Canada
1980 - 1983 Graduate Research Assistant in Marine Biology, Department of Zoology, University of Guelph, Ontario, Canada
1978 - 1980 Science Subvention Researcher in Bioenergetics, Federal Fisheries Research Station St. Andrews, NB, Canada
1976 - 1978 Graduate Research Assistant in Aquatic Toxicology, Department of Zoology, University of Guelph, Ontario, Canada
Academic Honours:
2004-2011 Tier 1 Canada Research Chair in Aquatic Toxicology 1985-1987 NRC Canadian Government Laboratory Visiting Fellowship, 1978-1979 Ontario Graduate Scholarship, University of Guelph, Canada. 1977-1978 Ontario Graduate Scholarship, University of Guelph, Canada. 1972 Ontario Scholarship, North Bay, Canada. 1972 City of North Bay Scholarship Award, North Bay, Canada. 1970 Grade 11 Academic Excellence Award, Ecole des Roches, Switzerland.
Scholarly and Professional Academic Activities:
Appointed to the Board of Directors of the Friends of the Second Marsh, May 2004-2007
Appointed by Senator Robert Hill, Minister for the Environment and Heritage, as expert in surface water ecotoxicology to the Alligator Rivers Region Technical Committee 30 June, 2001 – April, 2004
Member of the Academic Program Committee for the 7th Islands of the World: New Horizons in Island Studies conference June 26-30, 2002 at the University of Prince Edward Island, Canada
Vice-President of the Australasian Society for Ecotoxicology 1999-2002 and President- elect for 2003 (declined to return to Canada)
Chairman of the External Advisory Committee, Centre for Environmental Toxicology, University of Technology Sydney (UTS), Sydney, Australia 1999 – 2001
Page 2 of 12 UOIT CV- Dr D. A. Holdway 07/28/04 Scientific Program Committee for the Silver Anniversary International Heavy Metals Conference to be held in Ann Arbor, MI August, 2000.
Conference Organizer for Envirotox’99 Joint Conference of Royal Australian Chemical Institute (Environmental Division) and Australasian Society of Ecotoxicology, 7-10 February, 1999 Geelong, Australia.
Editorial Board member of the journal Chemosphere (Elsevier), 2003 -present.
Editorial Board member of the journal Marine Pollution Bulletin (Elsevier) 2001-present.
Editorial Board member of the journal the Science of the Total Environment (Elsevier) 1999 - present.
Advisory Board member of the journal Spill Science and Technology Bulletin (Pergamon/ Elsevier) 1999 - 2002.
Regional Editor (Japan and Australasia) of the journal Spill Science and Technology Bulletin (Elsevier) 1996-1999
Associate Editor of the Journal of Aquatic Ecosystem Stress and Recovery (Kluwer).1996-2002.
External Expert, UTS Review Committee for 5-year Review of Centre for Environmental Toxicology, UTS, Sydney, Australia July, 1997
President of Cranbourne Primary School Council (CPSC) 1997- 2002
Vice-President of Cranbourne Primary School Council (CPSC) 1996-1997 Chairman, Environment Committee, CPSC 1996-1997
National Association of Testing Authorities (NATA) Panel of Assessors for Biological Testing October, 1996 – present
Senior Executive Committee, Department of Applied Biology and Biotechnology 1996 – 2002
Research Grants Council of Hong Kong's external referee January, 1997 – present
Deputy-Chairman of RMIT's Higher Degrees Committee 1996-1997
Inaugural Victorian Representative to the Management Council of the Australasian Society for Ecotoxicology 1994-1998
Advisory Committee, Centre for Environmental Toxicology, UTS, Sydney, Australia 1994 - 2002
Australian Expert to the OECD Test Guidelines Program -Aquatic Toxicology 1991 - 2002
Page 3 of 12 UOIT CV- Dr D. A. Holdway 07/28/04 RMIT representative on the Queenscliff Marine Station Consortium Management Committee 1991- 2002
Invited lecture, "From the Land of Thunder to Port Phillip Bay in the Land Down Under: Biomonitoring in Australia – A Personal Odyssey" Faculty of Science, University of Prince Edward Island, Charlottetown, PEI, Canada. 26 June, 2001\
Invited lecture, "Mining and tropical freshwater environments: laboratory studies" Dept. of Biology, Warrnambool Campus, Deakin University, Victoria. 16 October, 1997
Invited lecture, "Use of Enzyme Biomarkers in Biomonitoring" Department of Biology, Warrnambool Campus, Deakin University, Warrnambool, Victoria 17/10/97.
Invited lecture,. "An Introduction to Ecotoxicology", Department of Pharmacology, Monash University, Clayton, Victoria 13/10/97.
Graduate Supervisions:
Master Candidates In Progress Completed Doctoral Candidates In Progress Completed TOTA L FT PT FT PT Senior Supervisor 3 Senior Supervisor 1 1 11 16 Other Supervisor 2 Other Supervisor 2 3 7 Total Masters 5 Total PhD’s 3 1 14 23
A list of some of my more recent graduate students (1997 – present) is provided below:
Student Yrs. Supervised Title of Project Present Position Mr. William Dixon, 1999-2004 Scale Issues in Ecotoxicology Submitted for PhD Submitted examination Victorian Department of Natural Resources, Australia
Ms Judith Platt 1999-2004 Effects of blue-green algae writing up, PhD Student (nodularin) toxin on black Commonweatlh bream. Department of Occupational Health and Safety
Mr Scott Raymond 1999-2004 Effect of pesticide mixtures on In progress-completing PhD Student freshwater organisms experiments and writing up
Page 4 of 12 UOIT CV- Dr D. A. Holdway 07/28/04 Dr Eugene Georgiades 1999-2003 The impact of petroleum Starting post-doc at hydrocarbon contamination on UOIT in Nov, 2004 PhD marine invertebrates
Dr Kelly Ryder 1999-2002 Effects of petroleum hydro- Starting post-doc at PhD carbons on echinoderms Marine Sciences Research Center, Stony Brook University, USA
Ms Caroline 1997-2000 Estrogenic effects of oil Research Officer, Teasdale dispersants on sand flathead University of Melbourne, MapplSci Australia
Dr Sara Long Research Scientist, 1996-2000 An investigation into marine PhD invertebrate biomarkers of NERC Centre for exposure to sub-lethal Ecology & Hydrology, concentrations of crude and Monks Wood, UK dispersed oil.
Dr Carmel Pollino Research Fellow, Water 1996-2000 The sublethal effects of crude PhD oil, dispersed crude oil and Studies Centre, Monash naphthalene on fish growth University, Australia and reproduction.
Dr Ismail Gulec Head, Editorial Team, 1995-1999 Ecotoxicological effects PhD of various oil spill Chemwatch, Melbourne, counter-measures on Victoria, Australia Australian marine organisms.
Dr Hamish Reid Senior Environmental 1993-1997 The use of bioindicators to PhD predict long term toxic effects Officer, Victorian EPA, to the crimson-spotted rainbow Melbourne, Australia fish (Melanotaenia fluviatilis) following pulse-exposure to endosulfan.
Dr Rick van Dam Senior Research 1993-1997 The effects of DTPA PhD exposure on metal-dependent Scientist, Ecotoxicology, processes of Australian Environmental Research freshwater organisms as Laboratory of the influenced by various biotic Supervising Scientist, and abiotic factors. Darwin, Australia
Page 5 of 12 UOIT CV- Dr D. A. Holdway 07/28/04 Graduate Courses:
2002 Environmental Toxicology, UPEI, Dept of Biology, Canada
1997-1999 Environmental Toxicology, RMIT-University, Australia
1996 Effects of Pollutants, Faculty of Environmental Engineering, University of Melbourne
External Research Funding
Name(s) Of Granting Bodies Principal Investigator Amount Year
Canada Research Chair (CRC) Yes $1,400,000 2004-2011 Canada Research Chair in Aquatic Toxicology
Canada Foundation for Innovation (CFI) Yes $125,000 2004 Development of continuous-flow wet-laboratory and controlled temperature room facilities for the investigation of pulse-exposure effects of contaminants on aquatic organisms and biomarker validation.
NSERC Discovery Grant - Group Yes $80,000 2003-2008 Principal with Dr Kevin Teather, Ecotoxicological impacts of land use on fish communities – deferred one year (2003-2004) due to laboratory construction at UOIT.
Australian Research Council Yes $137,000 2000-2003 Multi-generation assessment of potential endocrine disruptor contaminants using a model Australian freshwater fish
Hong Kong Research Grants Council No HK$763,200 2000-2002
City University of Hong Kong Strategic Grant No HK$250,000 2000-2002 Group with Br Bruce Richardson – co-applicant. Genotoxicity assays for environmental carcinogens in Hong Kong coastal waters
Department of Industry, Science Yes $27,000 1997-1999 and Tourism (DIST) Major Grant Environmental assessment of the efficacy or oil spill remediation and restoration technologies
Australian Research Council Yes $13,500 1998 Health status of fish populations in Port Phillip Bay
Page 6 of 12 UOIT CV- Dr D. A. Holdway 07/28/04 Internal Research Funding:
Name(s) Of Granting Bodies Principal Investigator Amount Year
RMIT National Competitive Grant Yes $20,000 1997 Scheme Support Program Grant Monitoring the ecotoxicity of accidental release of crude oil and oil-spill remedial actions in Australian marine organisms
RMIT National Competitive Grant Yes $10,000 1997 Scheme Support Program Grant Endocrine disruptive effects of crude oil and dispersed oil on fish
RMIT National Competitive Grant Yes $50,728 1996-1998 Scheme Support Program Grant Use of Octopus as a bioindicator species of inshore marine pollution by oil spills: detoxication enzyme and larval bioassays. (PhD Student Scholarship)
RMIT Research & Development Grant Yes $338,500 1995-1999 Oil Spill Research Program research assessing the toxicity of oil, dispersants, dispersed oil and burned oil residues to Australian marine species; quantitate oil tainting in fish and correlate with biomarkers of oil exposure.
Publications:
Total: 253 Refereed 103 (3 theses/books, 70 papers, 30 book chapters, proceedings and reports): Conference - 123: Book Reviews - 5: Others - 22. **Please note that when in Australia, since 1989 most papers were published in journals without page charges due to an Australian Research Council rule forbidding charging publication costs to grants.**
A. Articles in Refereed Journals (1998-present; 27 since 1998 and total of 70):
70. Ryder, K. J., A. Temara and D. A. Holdway 2004 (in press – accepted 13/08/02) The effects of crude-oil contaminated sediment on the behaviour of Australian seastars (Patiriella exigua) (Echinodermata: Asteroidea). Marine Pollution Bulletin,
69. Long, S.M., Ryder, K.J. and D.A. Holdway 2003. The use of respiratory enzymes as biomarkers of petroleum hydrocarbon exposure in Mytilus edulis planulatus. Ecotoxicology and Environmental Safety, 55(3):261-270.
68. Pollino, C.A. and D.A. Holdway 2003 Hydrocarbon-induced changes to the metabolic and detoxification enzymes of tissues in the Australian crimson-spotted rainbowfish (Melanotaenia fluviatilis). Environmental Toxicology, 18(1):21-28.
67. Pollino, C.A. and D.A. Holdway 2003 Reproduction of a laboratory-based population of the Australian Crimson-spotted rainbowfish (Melanotaenia fluviatilis). Australasian Journal of Ecotoxicology, 9:113-117.
Page 7 of 12 UOIT CV- Dr D. A. Holdway 07/28/04 66. Georgiades, E., Brennan, S., Butty, J., Holdway, D.A. and A. Temara 2003. The impact of oil derived products on the biology of the eleven-armed asteroid Coscinasterias muricata. Marine Environmental Research, 55(3):257-276.
65. Pollino, C.A. and D.A. Holdway 2002. Toxicity testing of crude oil and related compounds to early life stages of the crimson-spotted rainbowfish (Melanotaenia fluviatilis). Ecotoxicology and Environmental Safety, 52:180-189.
64. Orchard, S.J., D.A. Holdway, C. Barata and R.A. Van Dam 2002. A rapid response toxicity bioassay based on the feeding rate of the tropical cladoceran, Moinodaphnia macleayi. Ecotoxicology and Environmental Safety, 53:12-19.
63. Long, S. M. and D. A. Holdway 2002. Acute toxicity of crude and dispersed oil to Octopus pallidus (Hoyle, 1885) hatchlings. Water Research, 36(11):2769-2776.
62. *Holdway, D.A. 2002. The acute and chronic effects of wastes associated with offshore oil and gas production on temperate and tropical marine ecological processes. Marine Pollution Bulletin, 44(3): 185-203.
61. Pollino, C. A. and D. A. Holdway 2002. Reproductive potential of crimson-spotted rainbowfish (Melanotaenia fluviatilis) following short-term exposure to Bass Strait crude oil and dispersed crude oil. Environmental Toxicology, 17: 138-145.
60. Gagnon, M.M. and D.A. Holdway 2002. EROD activity, serum SDH and PAH biliary metabolites in sand flathead (Platycephalus bassensis) collected in Port Phillip Bay, Australia. Marine Pollution Bulletin, 44: 230-237.
59. *Holdway, D.A., K. Lok and M. Semaan 2001. The acute and chronic toxicity of cadmium and zinc to two hydra species. Environmental Toxicology, 16:557-565.
58. Semaan, M., D.A. Holdway and R.A. Van Dam 2001. Comparative sensitivity of three populations of the cladoceran Moinodaphnia macleayi to acute and chronic uranium exposure. Environmental Toxicology, 16(5):365-376.
57. Williams, N.D. and D.A. Holdway 2000 The effects of pulse-exposed cadmium and zinc on embryo hatchability, larval development and survival of Australian crimson-spotted rainbowfish (Melanotaenia fluviatilis). Environ. Toxicology, 15(3): 165-173.
56. Gulec, 1. and D.A. Holdway 2000.Toxicity of crude oil and dispersed crude oil to ghost shrimp Palaemon serenus and larvae of Australian bass Macquaria novemaculeata. Environ. Toxicol., 15: 91-98.
55. Gagnon, M.M. and D.A. Holdway 2000. EROD induction and biliary metabolite excretion following exposure to water accomodated fraction of crude oil and to chemically dispersed crude oil. Arch. Env. Contam. Toxicol., 38(1): 70-77.
54. Mitchell, F.M. and D.A. Holdway 2000. The acute and chronic toxicity of the dispersants Corexit 9500 and 9527, water accommodated fraction (WAF) of crude oil, and
Page 8 of 12 UOIT CV- Dr D. A. Holdway 07/28/04 dispersant enhanced WAF (DEWAF) to Hydra viridissima (green hydra). Water Research, 34(1): 343-348.
53. Gagnon, M.M. and D.A. Holdway 2000. EROD induction and biliary metabolite excretion following exposure to water accomodated fraction of crude oil and to chemically dispersed crude oil. Arch. Env. Contam. Toxicol., 38(1): 70-77.
52. *Temara, A., Gulec, I. and D.A. Holdway 1999. Oil-induced disruption of the foraging behaviour of the asteroid keystone predator, Coscinasterias muricata (Echinodermata). Marine Biology, 133: 501-507.
51. Pollino, C.A. and D.A. Holdway 1999. The potential of hydra species as standard toxicity test animals. Ecotoxicol. Environ. Safety, 43: 309-316.
50. Gagnon, M.M. and D.A. Holdway 1999. MFO induction in Atlantic salmon (Salmo salar) during and after exposure to Bass Strait crude oil. Australasian Journal of Ecotoxicology, 4:29-35.
49. Van Dam, R.A., M.J. Barry, J.T. Ahokas and D A. Holdway 1999. Investigating mechanisms of diethylenetriamine pentaacetic acid toxicity to the cladoceran, Daphnia carinata. Aquatic Toxicology, 46:191-210.
48. Van Dam, R.A., J.T. Ahokas and D.A. Holdway 1999. Chronic toxicity of of diethylenetriamine pentaacetic acid to crimson-spotted rainbow fish (Melanotaenia fluviatilis): effects on reproduction, condition and ethoxyresorufin O-deethylase activity. Ecotoxicol. Environ. Safety, 43: 74-82.
47. Gagnon, M.M. and D.A. Holdway 1999.Metabolic enzyme activities in fish gills as biomarkers of exposure to petroleum hydrocarbons. Ecotoxicol.ogy and Environmental Safety, 44: 92-99.
46. Van Dam, R.A., N.A. Porter, J.T. Ahokas and D.A. Holdway 1999. Stability of DTPA and Iron(Ill)-DTPA under simulated experimental conditions. Water Research, 33(5): 1320- 1324.
45. Van Dam, R.A., M.J. Barry, J.T. Ahokas and D.A. Holdway 1998. Effects of water- borne iron and calcium on the toxicity of diethylenetriamine pentaacetic acic (DTPA) to Daphnia carinata. Aquatic Toxicology, 42(l): 49-66
44. Gulec, I., B. Leonard and D.A. Holdway 1998. Oil and dispersed-oil toxicity to amphipods and snails. Spill Science & Technology Bulletin (1997), 4(l): 1-6.
43. Brumley, C.M., V.S. Haritos, J.T. Ahokas and D.A. Holdway 1998 The effects of exposure duration and feeding status on fish bile metabolises: Implications for biomonitoring. EcotoxicoL Environ. Saf., 39:147-153.
Papers under review
Page 9 of 12 UOIT CV- Dr D. A. Holdway 07/28/04 1. Georgiades, E.T., Temara, A. and D. A. Holdway (submitted 24 June, 2004) Examination of the reproductive cycle in two populations of Coscinasterias muricata in Port Philip Bay, Victoria, Australia. Marine Biology,
2. Georgiades, E.T., Temara, A. and D. A. Holdway (submitted 24 June, 2004) Influence of the reproductive cycle of the sea star Coscinasterias muricata upon expression of cytochrome P450 biotransformation enzymes. Comparative Biochemistry & Physiology C.
B. Refereed Book chapters and Monographs (1998-present; 2 since 1998, total of 30):
B30. Holdway, D.A. (invited chapter – in review). Hydra population reproduction toxicity test method. In: Small-scale freshwater environment toxicity test methods. (C. Blaise and J.F. Ferard, Editors), Kluwer Academic Publishers, for 2004 publication.
B29. Holdway, D.A., S.E. Brennan, V.S. Haritos, C.M. Brumley, and J.T. Ahokas. 1998. Development and evaluation of standardised methods for using liver MFO enzymes in two Australian marine fish as biomarkers of xenobiotic exposure. National Pulp Mills Research Program Technical Report No. 24, Canberra: CSIRO, 40 pp.
C. Recent Conference Abstracts ( 2001-2004 only; 48 since 1997, 13 since 2001 and total of 123):
C123. Georgiades, E., Danis, B., Gillan, D., Pernet, P., Dubois, P., Temara, A., Coloe, P. & D. Holdway, (2003). Impact of the reproductive cycle of female sea stars (Coscinasterias muricata, Echinodermata) on cytochrome P450 biotransformation enzymes. SETAC Asia Pacific/Australasian Society of Ecotoxicology 2003 Conference "Solutions to Pollution", 28th September - 1st October, Christchurch, New Zealand. Conference Programme and Abstracts pp. 23. Biomarkers session: Tuesday 30 September 2003.
C122. Ryder, K.J., Holdway, D. A., Temara, A. and E. Georgiades 2003. Stress protein expression in Australian seastars (Echinodermata) exposed to oiled sediment. Proceedings of the 24th Annual Meeting of the Society of Environmental Toxicology and Chemistry (SETAC), Austin, Texas USA, November 2003. Session: PM06 Linking Aquatic Toxicology with Ecosystem Indicators. Monday, 10 November 2003.
C121. Ryder, K.J., Holdway, D. A., and A. Temara, A. 2003. Foraging behavior of Australian seastars (Echinodermata) exposed to oil-contaminated sediment. Proceedings of the 24th Annual Meeting of the Society of Environmental Toxicology and Chemistry (SETAC), Austin, Texas USA, November 2003.Session: TP6 Effects of PAHs: Predicting Field Effects from Lab. Tuesday, 11 November 2003.
C120. Ryder, K.J., Holdway, D.A and A.Temara 2001. Behaviour of Australian seastars (Echinodermata: Asteroidea) exposed to crude-oil contaminated sediment. Proceedings of Envirotox 2001; From Reality to Regulation, Canberra, ACT 12-14 February, 2001. Abstract # E3, page 63 Australasian Society for Ecotoxicology, 156 pp.
Page 10 of 12 UOIT CV- Dr D. A. Holdway 07/28/04 C119. Bennett, C. E. and D. A. Holdway 2001. Biomarkers of low level contaminants in the blue mussel, Mytilus edulis planulatus L. Proceedings of Envirotox 2001; From Reality to Regulation, Canberra, ACT 12-14 February, 2001. Abstract # H4, page 77 Australasian Society for Ecotoxicology, 156 pp.
C118. Gagnon, M. M. and D. A. Holdway 2001. Exposure of fish to anthropogenic contaminants in Port Phillip Bay, Australia. Proceedings of Envirotox 2001; From Reality to Regulation, Canberra, ACT 12-14 February, 2001. Abstract # I12, page 96 Australasian Society for Ecotoxicology, 156 pp.
C117. Pollino, C. A., and D. A. Holdway. 2001. Examination of biomarkers in Crimson- spotted Rainbowfish (Melanotaenia fluviatilis) after exposure to waterborne 17-b-Estradiol and Naphthalene. Proceedings of Envirotox 2001; From Reality to Regulation, Canberra, ACT 12-14 February, 2001. Abstract # I27, page 111 Australasian Society for Ecotoxicology, 156 pp.
C116. Pollino, C. A., and D. A. Holdway. 2001. Changes in the reproductive potential of Crimson-spotted Rainbowfish (Melanotaenia fluviatilis) after exposure to hydrocarbons. Proceedings of Envirotox 2001; From Reality to Regulation, Canberra, ACT 12-14 February, 2001. Abstract # I28, page 112 Australasian Society for Ecotoxicology, 156 pp.
C115. Teasdale, C. D., Gagnon, M. M. and D. A. Holdway 2001. Vitellogenin measurement by ELISA in the Australian marine speices, sand flathead (Platycephalus bassenis). Proceedings of Envirotox 2001; From Reality to Regulation, Canberra, ACT 12- 14 February, 2001. Abstract # I33, page 117 Australasian Society for Ecotoxicology, 156 pp. C114. Teasdale, C. D., Gagnon, M. M. and D. A. Holdway 2001. Vitellogenin, bile metabolites, EROD activity and gonad histology as biomarkers in sand flathead (Platycephalus bassenis). Proceedings of Envirotox 2001; From Reality to Regulation, Canberra, ACT 12-14 February, 2001. Abstract # I34, page 118 Australasian Society for Ecotoxicology, 156 pp.
C113. Smith, A. H., Holdway, D. A. and R. A. van Dam 2001. Development and application of a rapid toxicity test based on feeding rate of a tropical cladoceran. Proceedings of Envirotox 2001; From Reality to Regulation, Canberra, ACT 12-14 February, 2001. Abstract # I40, page 124 Australasian Society for Ecotoxicology, 156 pp.
C112. Long, S. M. and D. A. Holdway 2001. Acute toxicity of crude oil and dispersed crude oil WAF to Octopus pallidus (Hoyle, 1885) hatchlings as modified by age of exposure. Proceedings of 11th Annual Meeting of SETAC Europe 6-10 May, 2001, Madrid, Spain.
C111. Ryder, K.J., Temara, A. and D. A. Holdway 2001. Effects of crude-oil contaminated sediment on the behaviour of an Australian seastar (Echinodermata: Asteroidea). Proceedings of the 3rd International Conference on Marine and Pollution Ecotoxicology, 10-14 June, 2001. Hong Kong, China. page O-1.
Page 11 of 12 UOIT CV- Dr D. A. Holdway 07/28/04 D. Other Publications: (1998-present; 7 since 1998 and total of 22)
D22. Wu, Rudolf, Paul Shin, David Randall, Paul Lam, Doris Au, Put Ang, Brian Morton, John Gray, John Giesy, Douglas Holdway, Klaus Koop, John Chapman, Michael Warne, Rosemarie Russo and David Phillips, 2002. Development of a Biological Indicator System for Monitoring Marine Pollution. Final Technical Report No. 1, Agreement No. CE 2/2001(EP), Centre for Coastal Pollution and Conservation, CityU Professional Services Limited in association with Atkins China Limited, Hong Kong, February 2002. 502 pp.
D21. Holdway, D.A. 2001. Review of Biochemical Biomarkers in Pollution Monitoring. Part of Hong Kong Government consultancy awarded to an international team entitled: “Development of a Biological Indicator System for Monitoring Marine Pollution”. November, 2001. 69 pp.
D20. Holdway, D.A. 2000. The acute and chronic effects of wastes associated with offshore oil and gas production on temperate and tropical marine ecological processes: A literature review. Safety and Environment Centre for Petroleum Development Japan. March, 2000. 43pp.
D19. Holdway, D.A. 1999. Animal ethics and ecotoxicology. Endpoint- Newsletter of the Australasian Society for Ecotoxicology, Vol.6(1): 5.
D18. Stauber, J., L. Gunthorpe, I. Anderson, D.A. Holdway, I. Gulec and K. Kevekordes 1997. Toxicity Testing of Melbourne Water's Eastern Treatment Plant Effluent -Progress Report (BRIEAP 3.1) CSIRO Investigation Report CET/IR 21R, Environmental Projects Office, December, 1997. 9 pp. plus appendices.
D17. Stauber, J., L. Gunthorpe, I. Anderson, D.A. Holdway, I. Gulec and K. Kevekordes 1997. Toxicity Testing of Melbourne Water's Eastern Treatment Plant Effluent -Progress Report (BRIEAP 3. 1) CSIRO Investigation Report CET/IR 4R, Environmental Projects Office, October, 1997. 8 pp. plus appendices.
D16. Stauber, J., L. Gunthorpe, I. Anderson, D.A. Holdway, I. Gulec and K. Kevekordes 1997. Toxicity Testing of Melbourne Water's Eastern Treatment Plant Effluent -Progress Report (BRIEAP 3. 1) CSIRO Investigation Report CET/IR 585R, Environmental Projects Office, June, 1997. 9 pp. plus appendices.
Page 12 of 12 Jones Taggart Page 1 of 3
Program: Applied Biosciences March 2005
CURRICULUM VITAE
Jones Taggart, D. Holly. Assistant Professor, tenure-track
DEGREES
Ph.D., Zoology (Molecular Biology), University of Western Ontario, 2000. B.Sc (Hons.), Biology, Queen’s University, 1994.
EMPLOYMENT HISTORY
2004- Assistant Professor, Faculty of Health Sciences, University of Ontario Institute of Technology 2004 Sessional Lecturer, Faculty of Nursing, University of Toronto 2000-03 Postdoctoral Researcher, Amgen Research Institute, Ontario Cancer Institute, University Health Network, Toronto, Ontario 1994-1999 Teaching Assistant, Department of Zoology, University of Western Ontario
GRADUATE SUPERVISIONS: N/A
GRADUATE COURSES: N/A
EXTERNAL RESEARCH FUNDING
Year Source Type* Amount/year Purpose
1998-99 Ontario Graduate Scholarship G 11 859 graduate fellowship 1997-98 Ontario Graduate Scholarship G 11 859 graduate fellowship 1998 Special Opportunities Grant G 3 000 doctoral research 1997 Special Opportunities Grant G 6 000 doctoral research
*Type- G: Government
INTERNAL RESEARCH FUNDING Year Source Amount Purpose
2004-10 UOIT 5000 education research 2004-06 UOIT 100 000 research 1999 Special University Scholarship, UWO 2 350 graduate research 1998 Special University Scholarship, UWO 2 500 graduate research 1997 Special University Scholarship, UWO 1 400 graduate research
Jones Taggart Page 2 of 3
PUBLICATIONS
Life-time summary
-papers in referred journals………………………………………………………………..6 - chapters in books…………………………………………………………………1 -technical reports…………………………………………………………………..1 -platform presentations ……………………………………………………………….…...3 -poster presentations ………………………………………………………………………5
Papers in referred journals
Jones D.H., Sanchez, O.H., Kozieradzki, I., Komarova, S.V., Sarosi, I., Morony, S., Rubin, E., Sarao, R., Hojilla, C.V., Kong, Y.Y., Dixon, S.J., Sims, S.M., Wada, T., Khokha, R., and Penninger, J.M. Chemotactic regulation of cancer cell migration and bone metastasis by RANKL. in prep.
Jones, D.H., Li, T.Y., Arystarkova, E., Barr, K.J., Wetzel. R., Peng, J., Markham, K., Sweadner, K., Fong, G-H. and Kidder, G.M. 2005. Na+,K+-ATPase from mice lacking the γ subunit (FXYD2) exhibits altered Na+ affinity and decreased thermal stability. Journal of Biological Chemistry. March 8 [epub ahead of print]
Jones D.H, Kong YY, Penninger JM. 2002. Role of RANKL and RANK in bone loss and arthritis. Annals of the Rheumatic Diseases. 61 (Suppl 2):ii32-9.
Jones, D.H., Golding, M.C., Barr, K.J., Fong, G-H. and Kidder, G.M. 2001. The mouse Na+-K+- ATPase γ –subunit gene (Fxyd2) encodes three developmentally regulated transcripts. Physiological Genomics. 6: 129-135.
MacPhee, D.J., Jones, D.H., Barr, K.J., Betts, D.H., Watson, A.J. and Kidder, G.M. 2000. Differential involvement of Na+, K+- ATPase isozymes in preimplantation development of the mouse. Developmental Biology. 222 (2): 486-498.
Barr, K.J., Garrill, A., Jones, D.H., Orlowski, J., and Kidder, G.M. 1998. Contributions of Na+/H+ exchanger isoforms to preimplantation development of the mouse. Molecular Reproduction and Development. 50: 146-153.
Jones, D.H., Davies, T.C. and Kidder, G.M. 1997. Embryonic expression of the putative γ subunit of the sodium pump is required for acquisition of fluid transport capacity during mouse blastocyst development. Journal of Cell Biology. 139(6): 1545-1552.
Chapters in books
Antisense Disruption of Gene Expression in the Preimplantation Embryo In Gardner, Lane and Watson (eds.) A Laboratory Guide to the Mammalian Embryo. (Oxford University Press, 2004)
Jones Taggart Page 3 of 3
Platform presentations
Jones, D.H. and Kidder, G.M. The sodium pump's γ subunit: genetic structure and function in the preimplantation embryo. Southern Ontario Reproductive Biology Meeting, May 1999, London, ON, Canada
Jones, D.H. Antisense inhibition of the sodium pump’s γ subunit delays blastocoel formation during preimplantation development. 17th Great Lakes Mammalian Development Meeting, April 1997, Toronto, ON, Canada
Jones, D.H. and Kidder, G.M. Embryonic expression and role of the putative γ subunit of the sodium pump in preimplantation development. Canadian Society of Zoologists 36th Annual meeting, May 1996, London, ON, Canada
Poster presentations
Jones, D.H., Dubik, D., Greenberg, A.H., and Penninger, J.M. Genomic structure of BNip3, a hypoxia induced pro-apoptotic protein. Amgen Research Institute Cancer Biology Conference, May 2001, Thousand Oaks, CA, U.S.A.
Jones, D.H., Golding, M.C., and Kidder, G.M. Expression of sodium pump γ subunit isoforms in preimplantation mouse development. Gordon Research Conference on Mammalian Gametogenesis and Embryogenesis, July 2000, New London, Connecticut, U.S.A. Jones, D.H., Golding, M.C. and Kidder, G.M. Alternate transcripts encode the Na+,K+- ATPase γ subunit. American Society for Cell Biology 39th Annual Meeting, December 1999, Washington D.C, U.S.A.
Jones, D.H. and Kidder, G.M. A reduction in sodium pump γ subunits by antisense treatment indirectly effects cation transport in the preimplantation mouse embryo. Gordon Research Conference on Mammalian Gametogenesis and Embryogenesis, July 1998, Plymouth State College, New Hampshire, U.S.A.
CURRICULUM VITAE
Fedor Naumkin Assistant professor (Chemistry), tenure-track, core faculty (UOIT/Science)
DEGREES Ph.D. in Physics, General Physics Institute (Russ. Acad. Sci.), Russia, 1992 M.Sc. I hons in Physics, Moscow Engineering Physics Institute, Russia, 1987
EMPLOYMENT HISTORY
2004- Assistant Professor, Faculty of Science, Univ. of Ontario Inst. of Technology 1998-2004 Visiting Assistant Professor, Dept of Chemistry, Univ. of Toronto 1996-1998 Research Associate, Dept of Chemistry, Univ. of Waterloo Summer’96 INTAS Visiting Researcher, Dept of Chemistry, Univ. of Cambridge, UK 1995-1996 MPI Visiting Scientist, Inst. of Theor. Chemistry, Univ. of Stuttgart, Germany 1994-1995 Royal Society Postdoc Fellow, School of Chemistry, Univ. of Sussex, UK 1992-1994 Research Officer, General Physics Institute (Russ. Acad. Sci.), Russia 1987-1992 Research Associate, General Physics Institute (Russ. Acad. Sci.), Russia
SCHOLARLY AND PROFESSIONAL ACTIVITIES 11 University seminars, 35 Conference presentations
INTERNAL RESEARCH FUNDING 2004-2006 Start-up research grant (UOIT) $60,000
PUBLICATIONS
Total: - Papers in refereed journals…...... 45 - Papers in refereed conference proceedings…...... 3 - Abstracts…………………..…...... 5
Papers in refereed Journals (past 7 years):
1. S. Dobrin, X. Lu, F. Y. Naumkin, J. C. Polanyi, and J. Yang, Photoimprinting Br atoms at Si(111) from self-assembled monolayer of CH3Br(ad), with pattern retention. Submitted (2004). 2. S. Dobrin, J. B. Giorgi, F. Y. Naumkin, and J. C. Polanyi, Photoinduced charge-transfer - + reaction at surfaces: III. (HF)m··Nan /LiF(001) + h (640 nm) (HF)m-1F Nan /LiF(001) + H(g). Submitted (2004). 3. F. Y. Naumkin and F. R. W. McCourt, Ab initio-based PES extrapolated using 3 - transferable atom-atom potentials, and predicted MW spectrum of the Ar-O2 (X g ) complex. Molecular Physics 102 (2004) 37-45. 4. S. Dobrin, H. He, F. Y. Naumkin, J. C. Polanyi, and S. A. Raspopov, Photoinduced - charge-transfer reaction at surfaces. Part II. HBr··Nan /LiF(001) + h (610 nm) Br + Nan /LiF(001) + H(g). J. Chem. Phys. 119 (2003) 9795-9803. 5. F. Y. Naumkin, J. C. Polanyi, D. Rogers, W. Hofer, and A. Fisher, Electron-induced attachment of chlorinated benzenes to Si(100)2x1. Surface Science 547 (2003) 324-334. 6. F. Y. Naumkin, J. C. Polanyi, and D. Rogers, Reaction of chlorinated benzenes with Si(100)2x1: a theoretical study. Surface Science 547 (2003) 335-348. 7. F. Y. Naumkin and D. J. Wales, Diatomics-in-molecules potentials incorporating ab initio data: Application to ionic, Rydberg-excited, and molecule-doped rare gas clusters. Computer Physics Communications 145 (2002) 141-155. 8. J. N. Murrell, F. Y. Naumkin, and C. R. Griffiths, The structures and stabilities of mixed + + inert gas cluster ions: NeHen and ArHen . Molecular Physics 99 (2001) 115-132. 1 + 9. F. Y. Naumkin, Binding in the Ar-I2(X g ) complex: A challenge for theory and experiment. ChemPhysChem 2 (2001) 121-125 [@ Angew. Chemie 40 (2001) No. 4]. 10. F. Y. Naumkin and D. J. Wales, Molecule-doped rare gas clusters: Structure and stability 2 of ArnNO (X 1/2, 3/2), n 25, from new ab initio potential energy surfaces of ArNO. Molecular Physics 98 (2000) 219-229. 11. F. Y. Naumkin, Transition intensities in rare gas triatomic ions: DIM versus point- charge approximation. Chemical Physics 252 (2000) 301-314. 12. J. B. Giorgi, F. Y. Naumkin, J. C. Polanyi, S. A. Raspopov, and N. S.-K. Sze, Surface aligned photochemistry: Photodissociation of Cl2 and Cl2···Cl adsorbed on LiF (001) surface. J. Chem. Phys. 112 (2000) 9569-9581. - 13. F. Y. Naumkin, DIM models for RgX2 systems: Suppressed influence of spin-orbit - coupling and induced multipole effects for the Ar-I2 interaction. Chemical Physics 240 (1999) 79-92. 14. N. L. Doltsinis, P. J. Knowles, and F. Y. Naumkin, Induced dipole - induced dipole + interactions in Arn clusters. Molecular Physics 96 (1999) 749-755. 1 + 15. F. Y. Naumkin and F. R. W. McCourt, Is the Ar-Br2(X g ) Van der Waals complex linear rather than T-shaped? A study in terms of ab initio-based potential energy surfaces. Molecular Physics 96 (1999) 1043-1049. 16. F. Y. Naumkin and D. J. Wales, Rydberg excitations in rare gas atomic clusters:
Structure and electronic spectra of Arn* (3 n 25). Mol. Phys. 96 (1999) 1295-1304 17. F. Y. Naumkin, An “electrons-in-molecule” model for atom-atom representation of 3 - atom-molecule potentials, with application to the Ar-B2(X g ) complex. Physical Chemistry Chemical Physics 1 (1999) 3949-3954. 18. F. Y. Naumkin, Single- versus multi-state DIM model for RgX2 systems: On the influence of spin-orbit coupling on Ar-I2 potentials. Chemical Physics 226 (1998) 319- 335; 230 (1998) 345. + 19. F. Y. Naumkin and D. J. Wales, Structure and properties of Nen clusters. Molecular Physics 93 (1998) 633-648. 20. F. Y. Naumkin and F. R. W. McCourt, Contributions of the two conformers to the MW spectrum and scattering cross section of the He-Cl2 van der Waals system, evaluated from an ab initio potential energy surface. J. Chem. Phys. 108 (1998) 9301-9312. 21. F. Y. Naumkin and D. J. Wales, Influence of the atom-atom interaction anisotropy on the structure and stability of ArnCl2 clusters. Chem. Phys. Letters 290 (1998) 164-170. 22. F. Y. Naumkin and F. R. W. McCourt, Ab initio-based potential energy surfaces, microwave spectrum, and scattering cross section of the ground state Ne-Cl2 system. J. Chem. Phys. 109 (1998) 1271-1284. 23. F. Y. Naumkin and F. R. W. McCourt, On the influence of rare gas atom - chlorine ion potentials on the ground state Rg-Cl2 interaction. Chem. Phys. Letters 292 (1998) 63-70. 24. F. Y. Naumkin and F. R. W. McCourt, Ab initio-based potential energy surfaces and 1 + predicted microwave spectra of the Ar-I2(X g ) Van der Waals complex. Chemical Physics Letters 294 (1998) 71-78. 25. W. Jäger, Y. Xu, G. Armstrong, M. C. L. Gerry, F. Y. Naumkin, F. Wang, and F. R. W. McCourt, Microwave spectra of NeN2 van der Waals complex: Experiment and theory. J. Chem. Phys. 109 (1998) 5420-5432. 26. F. Y. Naumkin, Molecular versus atom-atom interaction anisotropy in the case of the Ar- N2 van der Waals system. Molecular Physics 90 (1997) 875-888. 27. F. Y. Naumkin and F. R. W. McCourt, A nontypical atom-diatom van der Waals interaction: Ar-C2. J. Chem. Phys. 107 (1997) 1185-1194. 28. F. Y. Naumkin and F. R. W. McCourt, A study of the ArCl2 van der Waals complex: Ab initio-based potential energy surfaces, the relative stability of conformers, and the “hidden” microwave spectrum. J. Chem. Phys. 107 (1997) 5702-5713.
Papers in Refereed Conference Proceedings:
1. A. J. Hudson, F. Y. Naumkin, H. B. Oh, J. C. Polanyi, and S. A. Raspopov, Dynamics of harpooning studied by transition state spectroscopy: III. LiFCH3. Faraday Discussions 118 (2001) 191-207. 2. J. B. Giorgi, T. G. Lee, F. Y. Naumkin, J. C. Polanyi, S. A. Raspopov, and J. Wang, Photoinduced charge-transfer reactions at surfaces: (HCl)mNan /LiF(001) + h (640 nm) (HCl)m-1ClNan /LiF(001) + H(g). Faraday Discussions 117 (2000) 85-97.
Abstracts:
1. G.-P. Jiang, X. K. Lu, C. Matta, F. Y. Naumkin, I. Petsalakis, J. C. Polanyi, H. Rajamma, D. Rogers, G. Theodorakopoulos, and J. Yang, Thermal, photo-induced and electron-induced reaction of adsorbates on Si, followed by STM. Abstracts of Papers of the Amer. Chemical Society 226 (2003) 248-COLL Part 1. 2. S. A. Dobrin, J. B. Giorgi, T. G. Lee, H. He, F. Y. Naumkin, J. C. Polanyi, S. A. Raspopov, and J. Wang, Dynamics of photoinduced charge-transfer reactions at surfaces: Hydrogen halides on sodium clusters preadsorbed on LiF(001). Abstracts of Papers of the Amer. Chemical Society 224 (2002) 280-COLL Part 1. 3. S. A. Raspopov, N. S. K. Sze, F. Y. Naumkin, J. B. Giorgi, and J. C. Polanyi, Photoinduced dynamics of Cl3 radical-molecule complex prepared and studied at LiF (001) surface. Abstracts of Papers of the Amer. Chem. Soc. 223 (2002) 093-PHYS Part 2. 4. J. B. Giorgi, T. G. Lee, A. J. Hudson, F. Y. Naumkin, H. B. Oh, P. Piecuch, and J. C. Polanyi, Harpooning studied by transition state spectroscopy, M···XR + h [M*···XR] + - [M ···XR ] products: Results for M = Li, X = F, R = CH3 or H. Abstracts of Papers of the Amer. Chemical Society 219 (2000) 053-COMP Part 1. 5. J. B. Giorgi, T. G. Lee, A. J. Hudson, F. Y. Naumkin, H. B. Oh, P. Piecuch, and J. C. Polanyi, Harpooning studied by transition state spectroscopy, M···XR + h [M*···XR] + - [M ···XR ] products (X = F, Cl, Br; R = H or CH3). Abstracts of Papers of the American Chemical Society 218 (1999) 388-PHYS Part 2.
SIGNATURE
DATE: 28.07.04 CURRICULUM VITAE
NAME:
Paal, Krisztina, Assistant Professor of Chemistry, tenure-track, Faculty of Science, University of Ontario Institute of Technology
DEGREES:
Ph.D. Chemistry, University of Toronto, Canada, 1996 Oklevel (accepted as M.Sc.) Chemistry, Eotvos Lorand University, Hungary, 1992
EMPLOYMENT HISTORY:
2004- Assistant Professor of Chemistry, Faculty of Science, University of Ontario Institute of Technology 2003-2004 Assistant Professor (Sessional), Department of Chemistry, Brock University 2001-2003 Visiting Scientist, Department of Chemistry, University of British Columbia 1997-2001 Senior Research Scientist, Pharmaceutical R&D, HUMAN Co. Ltd., Hungary 1996-1997 Postdoctoral Fellow, Department of Organic Chemistry and Biochemistry, Technical University of Munich, Germany 1996 Lecturer, Department of Chemistry, University of Toronto at Mississauga 1992-1996 Research and Teaching Assistant, Department of Chemistry, University of Toronto
GRADUATE SUPERVISIONS: N/A
GRADUATE COURSES: N/A
EXTERNAL RESEARCH FUNDING
Duration Type 1995-1996 Ontario Graduate Scholarship 1994-1995 Ontario Graduate Scholarship
1 INTERNAL RESEARCH FUNDING:
Duration Type Amount 2004-2006 University start-up grant $100,000 + $50,000 matching funds 1993-1994 Differential Fee Waiver Scholarship, University of Toronto 1993-1994 University of Toronto Open Doctoral Fellowship 1992-1993 Connaught Scholarship, University of Toronto
PUBLICATIONS:
- Papers in refereed journals ...... 5 - Abstracts and/or papers read...... 8 - Patents...... 2
Papers in refereed journals:
1. Paal, K., Ito, M., Withers S. G. (2004) Paenibacillus sp. TS12 glucosylceramidase – Kinetic studies of a novel sub-family of family 3 glycosidases and identification of the catalytic residues. Biochem. J. 378(1), 141-149
2. Paál, K., Müller, J., Hegedűs, L. (2001) High affinity binding of paclitaxel to human serum albumin. Eur. J. Biochem. 268(7), 2187-2191
3. Kluger, R., Paal, K., Adamson, J. G. (1999) An Ether-Linked Tetrafunctional Acylating Reagent and Its Cross-Linking Reactions with Hemoglobin. Can. J. Chem. 77(2), 271- 279
4. Paal, K., Jones, R. T., Kluger, R. (1996) A Site-Specific Tetrafunctional Reagent for Protein Modification: Cross-Linked Hemoglobin with Two Sites for Further Reaction. J. Am. Chem. Soc. 118, 10380-10383
5. Dankházi, T., Fekete, É., Paál, K., Farsang, G. (1993) Electrochemical Oxidation of Lysergic Acid Type Ergot Alkaloids in Acetonitrile. Part 1. Stoichiometry of the Anodic Oxidation Electrode Reaction. Anal. Chim. Acta 282, 289-296
Abstracts and/or papers read:
1. Paal, K., Withers S. G. Kinetic Studies of a Bacterial Glucocerebrosidase and Its Active Site Mutants. Poster. The 39th IUPAC Congress and 86th Conference of The Canadian Society for Chemistry. Ottawa, Ontario. August 2003.
2 2. Paal, K., Withers S. G. Kinetic Studies of a Bacterial Glucocerebrosidase and Its Active Site Mutants. Poster. The 3rd International Conference of the Canadian Proteomics Initiative. Vancouver, British Columbia. May 2003.
3. Paal, K., Withers S. G. Kinetic Studies of a Bacterial Glucocerebrosidase and Its Active Site Mutants. Poster. PENCE Annual General Meeting. Vancouver, British Columbia. May 2003.
4. Paál, K., Müller, J., Hegedűs, L. Paclitaxel Binding to Human Serum Albumin – Determination of the Binding Constants. Poster. International Symposium on Serum Albumin and α1-Acid Glycoprotein. Kumamoto, Japan. October 2000.
5. Paál, K. Paclitaxel Binding to Human Serum Albumin – Determination of the Binding Constants. Oral presentation. Competition for young investigators in memoriam Otto Clauder. Hungarian Pharmaceutical Society, Budapest, Hungary. September 2000.
6. Paal, K., Kluger, R. Multifunctional Cross-Linking Reagents for Hemoglobin Modification. Invited presentation. Hemosol Inc., Etobicoke, Ontario. September 1995.
7. Paal, K., Kluger, R. Multifunctional Cross-Linkers. Cross-Linked Hemoglobin as a Drug Delivery Agent. Poster. The Fifth Annual Meeting of the Protein Engineering Network of Centres of Excellence. Saskatoon, Saskatchewan. June 1995.
8. Paal, K., Kluger, R. Four-Headed Cross-Linkers for Hemoglobin. Poster. The Third Annual Meeting of the Protein Engineering Network of Centres of Excellence. Edmonton, Alberta. June 1993.
Patents:
1. Hegedűs, L., Krempels, K., Paál, K., Pethő, G. Pharmaceutical Compositions Containing Plasma Protein. (WO 99/13914)
2. Kluger, R., Paal, K. Multifunctional Cross-Linking Reagents for Hemoglobin and Cross- Linked Hemoglobin Conjugates. (WO 97/00236)
DATE: January, 2005
3
Sanchez 1 of 7
CURRICULUM VITAE
Program: Applied Biosciences April 2005
a) NAME:
Sanchez, Otto, Associate Professor, tenured Member of the Graduate Faculty: yes b) DEGREES:
Ph.D. Biomedical Sciences, McMaster University, Canada, 1997 M.Sc. Pathology, University of Toronto, Canada, 1990 Specialist in Pathology, National Cancer Institute, Colombia, 1988 Medical Doctor, National University, Colombia, 1983 c) EMPLOYMENT HISTORY:
2003- Associate Professor, Faculty of Health Sciences, University of Ontario Institute of Technology
2003-2005 Clinical Appointment, School of Nursing, McMaster University
2002-2003 Associate Professor, School of Nursing, McMaster University
1998-2004 Research Associate, Ontario Cancer Institute/Princess Margaret Hospital
1997-2003 Public Health Consultant, Public Health Research, Education and Development Program, Social Services and Public Health Services Department
1996-2002 Assistant Professor, School of Nursing, McMaster University
1996-1998 Post-Doctoral Fellow, Ontario Cancer Institute/Princess Margaret Hospital and London Regional Cancer Centre
1994-1996 Assistant Coordinator, Health Sciences Courses, School of Nursing, McMaster University
1995-1996 Sessional Lecturer, School of Nursing, McMaster University
1983-1984 Rural Physician, Colombian Army
DATE: April 8, 2005
Sanchez 2 of 7 d) HONOURS:
Teaching Excellence Award, McMaster Students’ Union, 2000 Teaching Excellence Award, McMaster Students’ Union, 1998 Minority Scholar Award, American Association for Cancer Research, 1998 Teaching Excellence Award, McMaster Students’ Union, 1996 Minority Scholar Award, American Association for Cancer Research, 1994 Lorne F. Lambier, Q.C., Scholarship, McMaster University, 1994 Centennial Scholarship, McMaster University, 1994 Ontario Graduate Scholarship, Province of Ontario, 1989-1993 Open Master’s Fellowship, University of Toronto, 1989 e) SCHOLARLY AND PROFESSIONAL ACTIVITIES:
2004- Member, Information Technology Operations Committee, UOIT 2004- Member, Board of Directors, Research Institute at Lakeridge Health 2004- Member, Research Board of the Academic Council, UOIT 2004- Member, Sciences in Health Committee, Health Sciences, UOIT 2004- Member, Teaching Innovation Fund Review Committee, UOIT 2004- Member, Tenure and Promotions Committee, UOIT 2003- Member, Academic Council, UOIT 2003- Member, Education Research Group, Health Sciences, UOIT 2003- Member, Evaluation Committee, Health Sciences, UOIT 2003-04 Member, Curriculum Committee, Health Sciences, UOIT 2003-04 Member, Information Technology Council, UOIT 2004 Consultant, Faculty of Medicine, Universidad de la Frontera, Chile 2004 Consultant, Faculty of Nursing, Universidad San Luis Potosi, Mexico 2004 Reviewer, Brain Research 2002 Consultant, Faculty of Nursing, Universidad San Luis Potosi, Mexico 2002 Examiner, Comprehensive Examination, Mary Guise, PhD candidate 2001 Member, Learning Technologies Working Group, McMaster University 2000-03 Member, Committee for Scholarly Activities, McMaster University 2000-02 Member, Project Advisory Committee, Toronto Public Health 1999 Consultant, School of Nursing, Universidade de Sao Paulo, Brasil 1999 Consultant, Faculty of Medicine, Universidad de Tucuman, Argentina
DATE: April 8, 2005
Sanchez 3 of 7
1998-03 Graduate Faculty, Clinical Health Sciences, McMaster University 1998-03 Founder and Coordinator, Environment and Cancer Working Group 1998-00 Member, Learning Technology Committee, Health Sciences, McMaster University 1998-99 Member, Effective Public Health Practice Project, PHRED 1998 Consultant, GlycoDesign Ltd., Toronto 1998 Consultant, McMaster-CIDA Project, Chile f) GRADUATE SUPERVISIONS:
None g) GRADUATE COURSES:
Course Founder and Professor:
1999-03 Clinical Applications in Advanced Pathophysiology, McMaster University
Seminars:
1999- Environmental Epidemiology, University of Toronto 1999-03 Pathophysiological Concepts, University of Toronto 1999-03 Clinical Applications in Advanced Pathophysiology 1999-02 Advanced Cell Biology for Physical Scientists, University of Toronto
h) EXTERNAL RESEARCH FUNDING:
Year Source Type* Amount per year Purpose**
2003 CIHR Molecular Determinants in a Novel Mouse Model of Human Osteosarcoma C $133,750 per year (3yrs)
Principal investigator: R. Khokha
DATE: April 8, 2005
Sanchez 4 of 7
i) PUBLICATIONS:
1) Life-time summary (count) according to the following categories:
- Books authored...... 0 - Books edited ...... 0 - Chapters in books...... 3 - Papers in refereed journal...... 28 - Papers in refereed conference proceedings...... 0 - Technical reports ...... 0 - Abstracts and/or papers read...... 27 - Others (workshops presented)...... 0
2) Details for past seven (7) years same categories as above: books, chapters in books, papers in refereed journals.
Chapters in books:
1. “Using problem-based learning in distance education”, in E. Rideout (ed), Transforming nursing education through problem-based learning (Jones and Bartlett Publishers, 2001) pp 311-324
2. “Tumor suppressive capabilities of TIMP-1 in transgenic mouse models”, in S.P. Hawkes, D.R. Edwards and R. Khokha (eds), Tissue inhibitors of metalloproteinases in development and disease (Harwood Academic Publishers, 2000) pp 179-186
Papers in refereed journals:
1. Backman, S.A., Ghazarian, D., So, K., Sanchez, O., Wagner, K.-U., Hennighausen, L., Suzuki, A., Tsao, M.-S., Chapman, W.B., Stambolic, V., Mak, T.W., Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten. Proceedings of the National Academy of Sciences USA 101:1725-1730, 2004
2. Chia, M.C., Shi, W., Li, J.H., Sanchez, O., Strathdee, C.A., Huang, D., Busson, P., Klamut, H.J., Liu, F.F., A conditionally replicating adenovirus for nasopharyngeal carcinoma gene therapy. Molecular Therapy 9:804- 817, 2004
DATE: April 8, 2005
Sanchez 5 of 7
3. McPherson, J.P., Lemmers, B., Chahwan, R., Pamidi, A., Migon, E., Matysiak-Zablocki, E., Moynahan, M.E., Essers, J., Hanada, K., Poonepalli, A., Sanchez-Sweatman, O., Khokha, R., Kanaar, R., Jasin, M., Hande, M.P., Hakem, R., Involvement of mammalian Mus81 in genome integrity and tumor suppression. Science 304:1822-1826, 2004
4. McPherson, J.P., Lemmers, B., Hirao, A., Hakem, A., Abraham, J., Migon, E., Matysiak-Zablocki, E., Tamblyn, L., Sanchez-Sweatman, O., Khokha, R., Squire, J., Hande, M.P., Mak, T.W., Hakem, R., Collaboration of Brca1 and Chk2 in tumorigenesis. Genes & Development 18:1144-1153, 2004
5. Mohammed, F.F., Smookler, D.S., Taylor, S.E.M., Fingleton, B., Kassiri, Z., Sanchez, O.H., English, J.L., Matrisian, L.M., Au, B., Yeh, W.-C., Khokha, R., Abnormal TNFα activity in Timp-3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration. Nature Genetics 36:969-977, 2004
6. Yip, K.W., Li, A., Li, J.H., Shi, W., Chia, M.C., Rashid, S.A., Mocanu, J.D., Louie, A.V., Sanchez, O., Huang, D., Busson, P., Yeh, W.C., Gilbert, R., O’Sullivan, B., Gullane, P., Liu, F.F., Potential utility of BimS as a novel apoptotic therapeutic molecule. Molecular Therapy 10:533-544, 2004
7. Griffiths, E.K., Sanchez, O., Mill, P., Krawczyk, C., Hojilla, C.V., Rubin, E., Nau, M.M., Khokha, R., Lipkowitz, S., Hui, C.-C., Penninger, J.M., Cbl-3- deficient mice exhibit normal epithelial development. Molecular Cell Biology 23:7708-7718, 2003
8. Li, J.-H., Shi, W., Chia, M., Sanchez-Sweatman, O., Siatskas, C., Huang, D., Busson, P., Klamut, H., Yeh, W.-C., Richardson, C., O’Sullivan, B., Gullane, P., Neligan, P., Medin, J., Liu, F.-F., Efficacy of targeted FasL in nasopharyngeal carcinoma. Molecular Therapy 8:964-973, 2003
9. Moorehead, R.A.*, Sanchez, O.H.*, Baldwin, R.M., Khokha, R., Transgenic overexpression of IGF-II induces spontaneous lung tumors: A model for human lung adenocarcinoma. Oncogene 22:853-857, 2003 (*Both authors contributed equally to this study)
10. Leco, K.J., Waterhouse, P., Sanchez, O.H., Gowing, K.L., Poole, A.R., Wakeham, A., Mak, T.W., Khokha, R., Spontaneous air space enlargement in the lungs of tissue inhibitor of metalloproteinases-3 (TIMP- 3) deficient mice. Journal of Clinical Investigation 108:817-829, 2001
DATE: April 8, 2005
Sanchez 6 of 7
11. Zhu, Z., Sanchez-Sweatman, O., Huang, X., Wiltrout, R., Khokha, R., Zhao, Q., Gorelik, E., Anoikis and metastatic potential of Cloudman S91 melanoma cells. Cancer Research 61:1707-1716, 2001
12. Campbell, M., Buckeridge, D., Dwyer, J., Fong, S., Mann, V., Sanchez- Sweatman, O., Stevens, A., Fung, L., A systematic review of the effectiveness of environmental awareness interventions. Canadian Journal of Public Health 91:137-143, 2000
13. Ibrahim, T., Leong, I., Sanchez-Sweatman, O., Khokha, R., Sodek, J., Tenenbaum, H.C., Ganss, B., Cheifetz S., Expression of bone sialoprotein and osteopontin in breast cancer bone metastases. Clinical and Experimental Metastasis 18:253-260, 2000
14. Martin, D.C., Sanchez-Sweatman, O.H., Ho, A.T., Inderdeo, D.S., Khokha, R., Transgenic TIMP-1 inhibits simian virus 40 T antigen-induced hepatocarcinogenesis by impairment of hepatocellular proliferation and tumor angiogenesis. Laboratory Investigation 79:225-234, 1999
15. Poepping, T.L., Wyman, D.R., Sanchez-Sweatman, O.H., Chow, T.M., Long exposure growth of in-vivo interstitial laser photocoagulation lesions. Lasers in Medical Science 14:297-306, 1999
16. Sanchez-Sweatman, O.H., Orr, F.W., Singh, G., Human metastatic prostate PC3 cell lines degrade bone using matrix metalloproteinases. Invasion & Metastasis 18:297-305, 1999
17. Krüger, A.*, Sanchez-Sweatman, O.H.*, Martin, D.C., Fata, J.E., Ho, A.T., Orr, F.W., Rüther, U., Khokha, R., Host TIMP-1 overexpression confers resistance to experimental brain metastasis by a fibrosarcoma cell line. Oncogene 16:2419-2423, 1998 (* Both authors contributed equally to this study)
18. Van Meyel, D.J., Sanchez-Sweatman, O.H., Kerkvliet, N., Stitt, L., Ramsay, D.A., Khokha, R., Chambers, A.F. & Cairncross, J.G., Genetic background influences timing, morphology and dissemination of lymphomas in p53-deficient mice. International Journal of Oncology 13:917-922, 1998
19. Xu, F., Carlos, T., Sanchez-Sweatman, O.H., Khokha, R., Gorelik, E., Inhibition of VLA-4 and up-regulation of TIMP-1 expression in B16BL6 melanoma cells transfected with MHC class I genes. Clinical and Experimental Metastasis 16:358-370, 1998
DATE: April 8, 2005
VOLUME III: Curricula Vitae – Prospective Consultants
Consultant
Atkinson, Jeffrey Burka, John F. Curry, R. Allen Dixon, D. George Metcalfe, Chris Mulligan, Lois Schraft, Heidi Van Der Kraak, Glen
-1- RESUME FOR PROPOSED CONSULTANT
PROGRAM: Master of Science in Applied Bioscience
1. NAME OF PROPOSED CONSULTANT: Jeffrey Atkinson
2. RANK: Associate Professor
3. INSTITUTION: (include mailing address, telephone and fax numbers and E-mail address)
Institution: Brock University Mailing Address: 500 Glenridge Ave Tel: (905) 688-5550 ext 3967 Fax: (905) 682-9020 Email: [email protected] Website: http://www.brocku.ca/chemistry/faculty/Atkinson/
4. DEGREES UNIVERSITY DISCIPLINE DATE PhD Univ. of Ottawa Chemistry 1989 BSc (Hons) Trent Univ. Chemistry 1983
5. AREA(S) OF SPECIALIZATION: (relate this to those offered by the program being appraised). Organic synthesis, bioorganic chemistry, tocopherol (vitamin E) biochemistry, lipid transfer proteins, fluorescent lipid ligands, isotopic synthesis, polyamine biochemistry
6. Experience/Expertise relevant to service as a consultant (e.g. membership on editorial boards, administrative experience, academic recognition). A short statement regarding the appropriateness of the nominee as a consultant for this program would help the committee. Atkinson has an established research record in bioorganic chemistry encompassing organic synthesis of molecules of biological interest, and the design, synthesis, and use of molecules as probes of biological systems. He publishes in an array of journals spanning these sub-disciplines including Journal of Organic Chemistry, Biochemistry, Journal of Lipid Research, Bioorganic and Medicinal Chemistry, Phytochemistry and others in the nutritional biochemistry area. He does not currently serve on any editorial positions, but regularly reviews manuscripts for Journal of Organic Chemistry, Journal of Biological Chemistry, Journal of Lipid Research, Molecular Biology, Proteomics, and Phytochemistry.
Atkinson has also been the Chair of the Department of Chemistry at Brock University from 2002-2005, the Director of the Centre for Biotechnology at Brock for 2000-2002, a member of the Senate for Brock University, and the Chair of the Senate Committee on Graduate Studies (2003-04) and the Committee on University Infrastructure (2004-05). He has also been part of the author team responsible for writing the application to OCGS for Brock’s graduate program in Biotechnology (2000) and its review in 2003. He is currently leading his department in the development of an application for a PhD in Chemistry at Brock University.
1 7. Recent scholarly activity (if possible cite 3 to 5 recent publications giving title, date, kind of publication, journal, or publisher if a book).
Recent Journal Articles
Samantha Morley, Candance Panagabko, Diana Shineman, Achim Stocker, Jeffrey Atkinson and Danny Manor Molecular Determinants of Heritable Vitamin E Deficiency. Biochemistry 2004, 43, 4143-4149.
Bradford A, Atkinson J, Fuller N, Rand RP. The effect of vitamin E on the structure of membrane lipid assemblies. J Lipid Res. 2003, 44(10):1940-5.
Candace Panagabko, Samantha Morley, Marta Hernandez, Patrick Cassolato, Heather Gordon, Rachel Parsons, Danny Manor and Jeffrey Atkinson. Ligand specificity in the CRAL-TRIO protein family. Biochemistry 2003, 42(21), 6467-6474
Solomon Fixon-Owoo, Frédéric Levasseur, Keith Williams, Thomas N. Sabado, Mike Lowe, Markus Klose, A. Joffre Mercier, Paul Fields, Jeffrey Atkinson. Preparation and Biological Assessment of Hydroxycinnamic Acid Amides of Polyamines Phytochemistry 2003, 63(3):315-34.
Lei, Huangshu; Jeffrey Atkinson. Hydrogen-deuterium scrambling during the reductive deuteration of alpha- and gamma-tocopherol chromenes Journal of Labeled Compounds and Radiopharmaceutical. 2001, 44, 215-223.
Lei, Huangshu,; Atkinson, J.K. Synthesis of phytyl and chroman derivatized photoaffinity labels based on α-tocopherol. Journal of Organic Chemistry. 2000, 65(8); 2560-2567.
8. Previous affiliation with the University if any (e.g. visiting professor - give dates, internal consultant, former employee, any former professor/student relationships with faculty members). Consultants should be at “arm’s length” from the program, which means not a close friend, not a regular and current collaborator, not having been supervised recently by, not having been a visitor/teacher for some time at, and not a former colleague. Full disclosure of all past affiliation is required to assist the committee in the selection and to ensure an arm’s-length relationship. Normally the Appraisal Committee will not select as consultants persons who may have been retained by the university to review the program.
Atkinson has never been affiliated with the Faculty of Science of the University of Ontario Institute of Technology. He was the Chair of Brock’s Department of Chemistry when Dr. Krisztina Paal was a Limited Term Appointment there in 2003-04.
9. Any major blocks of time over the next 12 to 18 months when the proposed consultant may not be available.
Atkinson is on sabbatical for July 1, 2005 to June 30, 2006, but is spending most of his time at Brock University. Brief trips of 1-2 weeks will take him to Vienna and Cornell University in the next year (dates not yet set).
2 Burka - CV Page 1 of 3
RESUME FOR PROPOSED CONSULTANT
PROGRAM: MSc in Applied Bioscience
1. NAME OF PROPOSED CONSULTANT: Dr. John F. Burka
2. RANK: Professor
3. INSTITUTION: (include mailing address, telephone and fax numbers, E-mail address and, where available, the URL to the prospective consultant's web site.)
Dept. of Biomedical Sciences Atlantic Veterinary College University of Prince Edward Island Charlottetown, PEI ClA 4P3
TEL: (902) 566-08l0 FAX: (902) 566-0832 E-Mail: [email protected]
4. Degrees University Date Granted Area
B.Sc. University of Toronto 1972 Honours Science M.Sc. University of Guelph 1974 Pharmacology Ph.D. University of Guelph 1976 Pharmacology
5. AREA(S) OF SPECIALIZATION: (relate this to those offered by the program being appraised).
CURRENT RESEARCH ACTIVITY:
1. Biology of the host-parasite relationship between the copepodid parasite Lepeophtheirussalmonis and Atlantic salmon. 2. Developing alternative sea lice management strategies. 3. Investigate the roles of stress responses on the effectiveness of current and future therapeutic agents.
6. Experience/Expertise relevant to service as a consultant (e.g. membership on editorial boards, administrative experience, academic recognition). A short statement regarding the appropriateness of the nominee as a consultant for this program would help the committee.
Burka - CV Page 2 of 3
PROFESSIONAL MEMBERSHIPS AND ACTIVITIES:
Pharmacological Society of Canada - Member, Executive Council (1992-94) - Member, Nominating Committee (1994-95)
American Academy of Veterinary Pharmacology and Therpeutics - Member: Editorial Board, Journal of Veterinary Pharmacology and Therapeutics
Aquaculture Association of Canada - member
APICS Aquaculture Committee - Secretary: 1996-99 - Chairperson: 2000-2003
APICS Council Member: 2000-03 - Chair: Science Awareness Awards Committee: 2002-4
7. Recent scholarly activity (if possible cite 3 to 5 recent publications giving title, date, kind of publication, journal, or publisher if a book).
Papers in Refereed Journals
74. FAST, M.D., D.E. SIMS, J.F. BURKA, A. MUSTAFA, and N.W. ROSS (2002). Skin morphology and humoral non-specific defense parameters of mucus and plasma in rainbow trout, coho and Atlantic salmon. Comp. Biochem. Physiol. 132: 645-657.
75. FAST, M.D., A. MUSTAFA, D.E. SIMS , S.C. JOHNSON , G.A. CONBOY, G. JOHNSON , N.W. ROSS and J.F. BURKA (2002) Differences in susceptibility of rainbow trout (Oncorhynchus mykiss), coho salmon (Oncorhynchus kisutch) and Atlantic salmon (Salmo salar), to experimental infection with Lepeophtheirus salmonis: plasma and mucous biochemistry, immunology and skin histology. Dis. Aquat. Org. 52, 57-68.
76. BOWERS, J.M., D.J. SPEARE, and J.F. BURKA (2002). The effects of hydrogen peroxide on the stress response of Atlantic salmon (Salmo salar). J. Vet. Pharmacol. Ther. 25: 311-313.
77. FAST, M.D., J.F. BURKA, S.C. JOHNSON, and N.W. ROSS (2003). Enzymes released from Lepeophtheirus salmonis in response to mucus from different salmonids. J. Parasitol. 89: 7-13.
78. WESTCOTT, J.D., K.L. HAMMELL and J.F. BURKA (2004). Sea lice treatments, management practices and sea lice sampling methods on Atlantic salmon farms in the Bay of Fundy, New Brunswick, Canada. Aquaculture Research 34, 784-792. Burka - CV Page 3 of 3
79. FALLANG, A., J.M. RAMSAY, S. SEVATDAL, J.F. BURKA, K.L. HAMMELL, P. JEWESS, and T.E. HORSBERG. (2004). Evidence for occurrence of an organophosphate resistant type of acetylcholinesterase in strains of sea lice (Lepeophtheirus salmonis Krøyer). Pest Management Science 60, 1163-1170.
Books; Chapters in books
9. BURKA, J.F., M.D. POWELL, L.C. HUNTSMAN, D.J. SPEARE and G.M. WRIGHT (1992). Eosinophilic Granule Cells of Salmonids: A Potential Target for Anti- inflammatory Therapy? Proceedings of the American Academy of Veterinary Pharmacology & Therapeutics 8th Symposium, pp. 58-63.
10. FAST, M.D., ROSS, D.W., and J.F. BURKA (2000). Comparison of physiological and biochemical parameters in rainbow trout, coho and Atlantic salmon following infestation with sea lice (Lepeophtheirus salmonis), in ADisease Resistance and Immune Response@, C. Secombes, A. Ellis, D. MacKinlay (eds), American Fisheries Society, Bethesda, MD, pp. 44-47.
11. BURKA, J.F., G.A. CONBOY, D.E. SIMS, D.J. SPEARE, A. MUSTAFA, N.W. ROSS, and S.C. JOHNSON (2000). Physiological, biochemical, and histological approaches to examining sea lice-salmon interactions, in ADisease Resistance and Immune Response@, C. Secombes, A. Ellis, D. MacKinlay (eds), American Fisheries Society, Bethesda, MD, pp. 49-53.
8. Previous affiliation with the University of Ontario Institute of Technology if any (e.g. visiting professor - give dates, internal consultant, former employee, any former professor/student relationships with faculty members).
None
9. Any major blocks of time over the next 12 to 18 months when the proposed consultant may not be available.
None identified CV - RA Curry Page 1 of 3
RESUME FOR PROPOSED CONSULTANT
UOIT PROGRAM: Master of Science in Applied Bioscience
1. NAME OF PROPOSED CONSULTANT: Dr. R. Allen Curry
2. RANK: Director, Canadian Rivers Institute and Associate Professor, UNB
3. INSTITUTION: (include mailing address, telephone and fax numbers and E-mail address)
University of New Brunswick, Biology Department, P.O. Bag Service 45111, Fredericton, N.B.Canada E3B 6E1 Phone: (506) 453-4583 Fax: (506) 453-3583 Email: [email protected] Website - www.unb.ca/fredericton/science/biology/Faculty/Curry.html
4. DEGREES UNIVERSITY DISCIPLINE DATE
Hons. B.E.S. Waterloo Geography/Biology 1985 M.Sc. Trent Watershed Ecosystems 1988 Ph.D. Guelph Zoology 1993
5. AREA(S) OF SPECIALIZATION: (relate this to those offered by the program being appraised).
Fish behaviour, habitats, and population dynamics and the impacts of humans on aquatic ecosystems.
Special Responsibilities/Interests/Expertise: Assistant Professor, Biology and Forestry and Environmental Management New Brunswick Department of Natural Resources and Energy/Cloverleaf Foundation Professor of Recreational Fisheries Research Assistant Director, New Brunswick Cooperative Fish and Wildlife Research Unit (NBCFWRU)
One of the fields in the proposed MSc in Applied Bioscience program is "Environmental Science and Health. Dr. Curry's research interests and work are compatible with this area of study.
CV - RA Curry Page 2 of 3
6. Experience/Expertise relevant to service as a consultant (e.g. membership on editorial boards, administrative experience, academic recognition). A short statement regarding the appropriateness of the nominee as a consultant for this program would help the committee. i) Canadian Rivers Institute – Director, January 1, 2005 to present ii) Canadian Rivers Institute – Acting Director, January 1, 2004 to December 31, 2004 iii) Biology Department UNB – Acting Chair, July 1 to December 31, 2002 iv) Biology Department UNB – Associate Chair, July 1, 2001 to January 1, 2005 v) Biology Department UNB – Acting Director of Graduate Studies, July 1 to August 31, 2002 vi) Associate Graduate Faculty, University of Guelph (1999 – present) vii) Board of Directors, National Resource Board, Trout Unlimited Canada (2003 - present) viii) Associate Editor, North American Journal of Fisheries Management and member of the Editorial Management Board, American Fisheries Society (1999 – 2003)
7. Recent scholarly activity (if possible cite 3 to 5 recent publications giving title, date, kind of publication, journal, or publisher if a book).
Gray, M.A., K.R. Munkittrick, and R.A. Curry. 2005. Impacts of non-point inputs from potato farming on populations of slimy sculpin (Cottus cognatus). Curry, R.A. and S. MacNeill. 2004. Population-level responses to sediment during early life in brook trout. J. N. Am. Benth. Soc. 23:140-150 Curry, R.A., D.A. Scruton, and K.D. Clarke. 2002. The thermal regimes of brook trout, Salvelinus fontinalis, incubation habitats and evidence of changes during forestry operations. Can. J. For. Res. 32:1200-1207. Gray, M.A., R.A. Curry, and K.R. Munkittrick. 2002. Non-Lethal Sampling Methods for Assessing Environmental Impacts Using a Small-Bodied Sentinel Fish Species. Water Quality Research Journal of Canada 37:195-211. Cunjak, R.A., R.A. Curry, K. Clarke and D.A. Scruton. 2004. Fish-forestry studies in Atlantic Canada, pp.439-462. In Fishes and Forests: an Approach to Fish-Forestry Interaction (Northcote, T.G. and G.F. Hartman, eds.). Blackwell Science. Oxford. Doherty, C.A., R.A. Curry, and K.R. Munkittrick. 2004. Adult white sucker show limited near point source discharges in a large Canadian river. In Borton DL, Hall TJ, Fisher RP, Thomas JF, eds, Pulp and Paper Mill Effluent Environmental Fate and Effects, DEStech Publication, Lancaster, PA, USA
8. Previous affiliation with the University of Ontario Institute of Technology (UOIT) if any (e.g. visiting professor - give dates, internal consultant, former employee, any former professor/student relationships with faculty members). Consultants should be at “arm’s length” from the program, which means not a close friend, not a regular and current collaborator, not having been supervised recently by, not having been a visitor/teacher for some time at, and not a former colleague. Full disclosure of all past affiliation is required to assist the committee in the selection and to ensure an arm’s-length relationship. Normally the Appraisal Committee will not select as consultants persons who may have been retained by the university to review the program.
NONE
CV - RA Curry Page 3 of 3
9. Any major blocks of time over the next 12 to 18 months when the proposed consultant may not be available.
Unknown at this time.
Dixon-CV Page 1 of 4
RESUME FOR PROPOSED CONSULTANT
PROGRAM: MSc in Applied Bioscience
1. NAME OF PROPOSED CONSULTANT: Dr. D. George Dixon
2. RANK: Professor, Dean of Science
3. INSTITUTION: (include mailing address, telephone and fax numbers and E-mail address)
University of Waterloo Waterloo, ON N2L 3G1 Office: ESC 252B Tel: 888-4567 x.2531 Fax: 746-2531 Email: [email protected]
Dr. Dixon's website http://sciborg.uwaterloo.ca/biology/people/faculty/ddxion/dixon.html
4. DEGREES UNIVERSITY DISCIPLINE DATE
BSc Sir George Williams 1972 MSc Concordia 1975 PhD Guelph 1980
5. AREA(S) OF SPECIALIZATION: (relate this to those offered by the program being appraised).
Research Interests include: Effects of toxic chemicals, including metals and oilsands process water, on aquatic organisms, principally fish. Biotic modifying factors of toxicity. Development of methods for environmental effects monitoring. Physiologically based pharmacokinetic modelling of contaminant levels in fish.
One of the fields in the proposed MSc in Applied Bioscience program is "Environmental Science and Health. Dr. Dixon's research interests and work are compatible with this area of study.
1 Dixon-CV Page 2 of 4
6. Experience/Expertise relevant to service as a consultant (e.g. membership on editorial boards, administrative experience, academic recognition). A short statement regarding the appropriateness of the nominee as a consultant for this program would help the committee.
Co-Chair, Organizing Committee, 32nd Annual Aquatic Toxicity Workshop, to be held at the Waterloo Inn, October 2005.
Consultant to the U.S. Department of Justice re industrial contaminant release to the Ohio River. Current commitment.
Co-Director, Network of Environmental Risk Assessment and Management. Current commitment.
Member of Working Group 3 (Biological Methods, Environmental Toxicology) International Standards Division, Standards Council of Canada. Current commitment.
Member, College of Reviewers, Canada Research Chair Program. Current commitment.
Consulting editor, Journal of Aquatic Ecosystem Stress and Recovery and Member of the Editorial Board, Ecotoxicology and Environmental Safety. Current commitments.
Senior advisor to Ontario Power Generation re: the toxicity of ash pond effluent at Lambton and Nanticoke generating stations. Current commitment.
Senior advisor to the U.S. Bureau of Land Management in the aquatic toxicology of fire retardants used in management of forest fires. Current commitment.
Senior advisor to ICI Canada re: the environmental impacts of mercury contaminated sediments in the St. Lawrence River, Cornwall, ON. Current commitment.
Periodic consultant to the Ontario Ministry of Environment and Energy regarding the Provincial Water Quality Objectives for numerous contaminants including: copper, lead, zinc, cadmium, polycyclic aromatic hydrocarbons, resin acids, arsenic, substituted benzenes. Ongoing commitment, 1985 to date.
Member, Board of Directors, Oil-Sands Reclamation Research Network, University of Alberta. Current commitment.
I review approximately eight research grant applications each year drawn from a number of agencies including NSERC (Research, Strategic, Industrial), FCAR, USEPA and NSF. Over the past four years this has involved two site visits, for committees which I chaired.
I currently hold membership in the Society of Environmental Toxicology and Chemistry, and the Aquatic Ecosystem Health and Management Society.
I review approximately 2.5 papers a month drawn from a variety of journals including Canadian Journal of Fisheries and Aquatic Sciences, Aquatic Toxicology, Environmental Science and Technology, Environmental Toxicology and Chemistry, Fish Physiology and Biochemistry, Pesticide Biochemistry and Physiology, Ecotoxicology, and Journal of Aquatic Ecosystem Health.
2 Dixon-CV Page 3 of 4
7. Recent scholarly activity (if possible cite 3 to 5 recent publications giving title, date, kind of publication, journal, or publisher if a book).
Gillis, P.L. D.G. Dixon, U. Borgmann and T.B. Reynoldson. 2004. Uptake and depuration of cadmium, nickel and lead in laboratory exposed Tubifex tubifex and corresponding changes in the concentration of a metallothionein-like protein. Environ. Toxicol. Chem. 23: 76-85.
Borgmann, U., M. Nowierski, L.C. Grapentine and D.G. Dixon. 2004. Assessing the cause of impacts on benthic organisms near Rouyn-Noranda, Quebec. Environ. Pollut. 129: 39-48.
Bartlett, A.J., U. Borgmann, D.G. Dixon, S.P. Batchelor and R.J. Maguire. 2004. Tributyltin (TBT) uptake and depuration in Hyalella azteca: implications for experimental design. Environ. Toxicol. Chem. 23: 426-434.
Gillis, P.L., T.B. Reynoldson and D.G. Dixon. 2004. Natural Variation in a metallothionein-like protein in Tubifex tubifex in the absence of metal exposure. Ecotox. Environ. Saf. 58: 22-28.
Campbell, L.M., J.S. Balirwa, D.G. Dixon and R.E. Hecky. 2004. Bioaccumulation of mercury in fish from Thruston Bay, Napoleon Gulf, Lake Victoria (East Africa). Afr. J. Aquat. Sci. 21: 91-96.
Borgmann, U., W.P. Norwood and D.G. Dixon. 2004. Re-evaluation of metal bioaccumulation and chronic toxicity in Hyalella azteca using saturation curves and the biotic ligand model. Environ. Pollut. 131: 469-484.
Bantseev, V., K.L. Moran, D.G. Dixon, J.R. Trevithick and J.G. Sivak. 2004. Optical properties, mitochondria and sutures of lenses of fishes: a comparative study of nine species. Can. J. Zool. 82: 86-93.
Bartlett, A.J., U. Borgmann, D.G. Dixon, S.P. Batchelor and R.J. Maguire. 2004. Accumulation of tributyltin in Hyalella azteca as an indicator of chronic toxicity: survival, growth and reproduction. Environ. Toxicol. Chem. 12: 2878-2888.
Diener, L.C., P.M. Schulte, D.G. Dixon and B.M. Greenberg. 2004. Optimization of differential display polymerase chain reaction as a bioindicator for the cladoceran, Daphnia magna, Environ. Toxicol. 19: 179-190.
Rhodes, S., A. Farwell, L.M. Hewitt, M. MacKinnon and D.G. Dixon. 2005. The effects of dimethylated and alkylated polycyclic aromatic hydrocarbons on the embryonic development of the Japanese medaka. Ecotox. Environ. Saf. 60: 247-258.
Bartlett, A.J., U. Borgmann, D.G. Dixon, S.P. Batchelor and R.J. Maguire. Toxicity and bioaccumulation of tributyltin in Hyalella azteca from freshwater harbour sediments in the Great Lakes Basin, Canada. Can. J. Fish. Aquatic Sci.: in press.
Borgmann, U., Y. Couillard, P. Doyle and D.G. Dixon. Toxicity of 63 metals and metalloids to Hyalella azteca at two levels of water hardness. Environ. Toxicol. Chem.: in press.
Nero, V., A. Farwell, A. Lister, G. Van Der Kraak, L.E.J. Lee, T. Van Meer, M.D. MacKinnon and D.G. Dixon. Gill and liver histopathological changes in yellow perch (Perca flavescens) and goldfish (Carassius auratus) exposed to oil sands process-affected water. Ecotox. Environ.: in press.
Nowierski, M., D.G. Dixon and U. Borgmann. Effects of water chemistry on the bioavailability of metals in sediment to Hyalella azteca: implications for sediment quality guidelines. Arch. Environ. Contam. Toxicol.: in press.
3 Dixon-CV Page 4 of 4
Borgmann, U., M. Noweirski and D.G. Dixon. Effect of major ions on the toxicity of copper to Hyalella azteca and implications for the Biotic Ligand Model. Aquat. Toxicol.: in press.
Mallakin, A., P.G. Mezey, Z. Zimpel, K.S. Berenhaut, B.M. Greenberg and D.G. Dixon. Use of quantitative structure-activity relationship to model the photoinduced toxicity of anthracene and oxgenated anthracenes. QSAR Combinatorial Sci.: in press.
Campbell, L.M., R.E. Hecky, D.G. Dixon and L.J. Chapman. Food web structure and mercury transfer in two contrasting Ugandan highland crater lakes. Agric. J. Ecol.: in press.
Dussault, E.B., R.C. Playle, D.G. Dixon and R.S. McKinley. Effects of chronic aluminum exposure on swimming and cardiac performance in rainbow trout, Oncorhynchus mykiss. Physiol. Biochem.: in press.
Campbell, L.M., S.B. Wandera, R.J. Thacker, D.G. Dixon and R.E. Hecky. Niche separation in the Nilotic icthyofauna of Lake Albert (Uganda): trophic generalists make good invaders. Environ. Biol. Fishes: in press.
Gillis, P.L., T.B. Reynoldson, D.G. Dixon and D. Milani. Assessing metal bioavailability after a mine tailings spill with metallothionein-like protein and tissue metal concentrations in T. tubifex. P. 000 000. In Integrated assessment and management of the ecosystems affected by the Aanalcollar mining spill (southwest Spain) (Del Valls and Blasco, eds.). 10C/ICAM/UNESCO Technical Report: in press.
8. Previous affiliation with the University of Ontario Institute of Technology (UOIT) if any (e.g. visiting professor - give dates, internal consultant, former employee, any former professor/student relationships with faculty members). Consultants should be at “arm’s length” from the program, which means not a close friend, not a regular and current collaborator, not having been supervised recently by, not having been a visitor/teacher for some time at, and not a former colleague. Full disclosure of all past affiliation is required to assist the committee in the selection and to ensure an arm’s-length relationship. Normally the Appraisal Committee will not select as consultants persons who may have been retained by the university to review the program.
None.
9. Any major blocks of time over the next 12 to 18 months when the proposed consultant may not be available.
At this time the following blocks of time are booked: May 21 – 30 June 20 – 24 October 3 – 5 January 23 – 26
4 Metcalfe Page 1 of 3
RESUME FOR PROPOSED CONSULTANT
PROGRAM: Master of Science in Applied Bioscience
1. NAME OF PROPOSED CONSULTANT: Chris Metcalfe
2. RANK: Professor
3. INSTITUTION: (include mailing address, telephone and fax numbers, E-mail address and, where available, the URL to the prospective consultant's web site.)
Trent University, Environmental and Resource Studies Program 1600 West Bank Drive, Peterborough, ON, K9J 7B8 T:705-748-1011, x7272; F:705-748-1569; [email protected]
4. DEGREES UNIVERSITY DISCIPLINE DATE
B.Sc. (Hons.) University of Manitoba Zoology 1973 M.Sc. U. New Brunswick Biology 1976 Ph.D. McMaster University Biochemistry 1984
5. AREA(S) OF SPECIALIZATION: (relate this to those offered by the program being appraised).
Environmental toxicology Analytical chemistry
6. Experience/Expertise relevant to service as a consultant (e.g. membership on editorial boards, administrative experience, academic recognition). A short statement regarding the appropriateness of the nominee as a consultant for this program would help the committee.
I have had extensive administrative experience in the area of graduate studies (see below) and during my career to date, I have supervised 18 M.Sc. and 5 Ph.D. students.
Administrative Experience: 1988 to 1991 Director, Watershed Ecosystems Graduate Program 1999 to 2000 Interim Director, Watershed Ecosystems Graduate Program 1995 to 1998 Chair, Environmental & Resource Studies, Trent University 2000 to 2004 Dean of Research and Graduate Studies, Trent University
1 Metcalfe Page 2 of 3
2002 to 2004 Director of the AINSTRUCT@ project in Watershed Ecosystems Management (Lead University - Trent U.) development project in Mexico and Ecuador funded through the Canadian International Development Agency (1996-2003).
Evaluation Experience: 1) Evaluator for the post-graduate awards competition of the Ontario Graduate Scholarships program (1987-89). 2) Evaluator for the "CIDA Awards for Canadians" Program for the Canadian Bureau for International Education (1990-1991). 3) Member of the Long Range Planning Committee of the Society of Environmental Toxicology and Chemistry (1994-1995 and 1998-99). 4) Member of the Editorial Board of the Society of Environmental Toxicology and Chemistry (1994-98). 5) Member of the Committee of the Canadian Foundation for Innovation (CFI) for evaluation of CFI applications from Canadian colleges (1999-2000). 7) Evaluated the Department of Physical Sciences of the University of New Brunswick at Saint John through the departmental evaluation program mandated by the Council of Maritime Universities (January-February, 2005).
7. Recent scholarly activity (if possible cite 3 to 5 recent publications giving title, date, kind of publication, journal, or publisher if a book).
Total peer-reviewed papers and book chapters (published or in press): 147
Belmont MA, E. Cantellano, S. Thompson, M. Williamson, A. Sánchez and C.D. Metcalfe. 2005. Treatment of domestic wastewater in a pilot-scale treatment wetland in central Mexico. Ecological Engineering 23:299-311.
Balch G.C., K. Shami, P. J. Wilson, Y. Wakamatsu and C.D. Metcalfe. 2004. Feminization of the FLFII strain of Japanese medaka (Oryzias latipes) exposed to 17β-estradiol, Environ. Toxicol. Chem. 11:2763-2768.
Miao, X-S., F. Bishay, M. Chen and C.D. Metcalfe. 2004. Occurrence of antimicrobials in the final effluents of wastewater treatment plants in Canada. Environ. Sci. Technol. 38:3533- 3541.
Metcalfe, C.D., Xiu-Sheng Miao, Wenyi Hua, R. Letcher and M. Servos. Pharmaceuticals in the Canadian Environment. 2004. In: Kümmerer, K. (Ed.), Pharmaceuticals in the Environment: Sources, Fate, Effects and Risks, Second Edition, Springer-Verlag, pp.67-87.
Kavanagh, R.J., G.C. Balch, Y. Kiparissis, A.J. Niimi, J. Sherry, C. Tinson and C.D. Metcalfe. 2004. Endocrine disruption and altered gonadal development in white perch (Morone americana) from the lower Great Lakes region. Environ. Health Persp. 112:898-902.
2 Metcalfe Page 3 of 3
Balch, C.G., C. Mackenzie and C.D. Metcalfe. 2004. Alterations to gonadal development and reproductive success in Japanese medaka (Oryzias latipes) exposed to 17∀- ethinylestradiol. Environ. Toxicol. Chem. 23:782-791.
Metcalfe, C.D., B.G. Koenig, T.L. Metcalfe, G. Paterson and R. Sears. 2004. Intra- and inter- species differences in persistent organic contaminants in the blubber of blue whales and humpback whales from the Gulf of St. Lawrence, Canada. Marine Environ. Res. 57:245-260.
8. Previous affiliation with the University of Ontario Institute of Technology if any (e.g. visiting professor - give dates, internal consultant, former employee, any former professor/student relationships with faculty members). Consultants should be at “arm’s length” from the program, which means not a close friend, not a regular and current collaborator, not having been supervised recently by, not having been a visitor/teacher for some time at, and not a former colleague. Full disclosure of all past affiliation is required to assist the committee in the selection and to ensure an arm’s-length relationship. Normally the Appraisal Committee will not select as consultants persons who may have been retained by the university to review the program.
I have had no previous affiliation with the University of Ontario Institute of Technology.
9. Any major blocks of time over the next 12 to 18 months when the proposed consultant may not be available.
August, 2005 and November, 2005
3 Mulligan, L. Page 1 of 2
RESUME FOR PROPOSED CONSULTANT
PROGRAM: MSc in Applied Bioscience
1. NAME OF PROPOSED CONSULTANT: Dr. Lois Mulligan
2. RANK: Professor, Pathology and Molecular Medicine
3. INSTITUTION: (include mailing address, telephone and fax numbers, E-mail address and, where available, the URL to the prospective consultant's web site.)
Division of Cancer Biology & Genetics Cancer Research Institute Botterell Hall, Rm 329 Queen's University Kingston, Ontario K7L 3N6, CANADA
TEL: (613) 533-6000 X-77475 FAX: (613) 548-1348 e-mail: mulligal (at) post.queensu.ca http://www.path.queensu.ca/kgh/genetics/members/mulligan.html
4. DEGREES UNIVERSITY DISCIPLINE DATE
5. AREA(S) OF SPECIALIZATION: (relate this to those offered by the program being appraised).
The primary interests of my group is in the relationship between the processes of normal and neoplastic growth. My specific area of interest is in the role of the RET proto-oncogene. Mutations in the RET gene are involved in the inherited cancer syndromemultiple endocrine neoplasia type 2 (MEN 2) and also in a common birth defect which affects the formation of nerves in the developing gut. Early recognition of these diseases, by identifying RET mutations, allows treatment before symptoms or complications develop which reduces morbidity and death for these patients. However, not all disease cases have detectable RET mutations. We need to identify new genes or mechanisms that might account for these diseases cases and allow us to improve our ability to diagnose prevent or treat the disease in these patients. My lab is investigating the normal functions of RET and the molecules with which it interacts in development of neural cell types and in tumours of neuorendocrine cell types.
6. Experience/Expertise relevant to service as a consultant (e.g. membership on editorial boards, administrative experience, academic recognition). A short statement regarding the appropriateness of the nominee as a consultant for this program would help the committee.
Mulligan, L. Page 2 of 2
7. Recent scholarly activity (if possible cite 3 to 5 recent publications giving title, date, kind of publication, journal, or publisher if a book).
1. Myers SM, Mulligan LM (2004). The RET receptor is linked to stress response pathways. Cancer Research. In press. 2. Vanhorne JB, Andrew SD, Harrison KJ, Taylor SAM, Thomas B, McDonald TJ, Ainsworth PJ, Mulligan LM (2004). A model of GFRa 4 function and a potential modifying role in multiple endocrine neoplasia 2. Oncogene. In press. 3. Andrew SD, Kuiper MJ, Mansergh FC, Wride MA, Rancourt DE, Mulligan LM (2002). Structural variation in a novel zinc finger protein and investigation of its role in Hirschsprung disease. Gene Function & Disease 3:69-76. 4. Andrew SD, Capes-David A, Delhanty P, Marsh DJ, Mulligan LM, Robinson BG (2002). A mitogen activated protein kinase-dependent signaling pathway in the repression of RET. Gene 298: 9-19. 5. Lui VC, Samy ET, Sham MH, Mulligan LM, Tam PKH (2002). Glia cell-line derived neurotrophic factor family receptors (GFRA) are abnormally expressed in aganglionic bowel of a sub population of patients with Hirschsprung's disease. Laboratory Investigation 82:703-712. 6. Carter MT, Yome JL, Marcil MN, Martin CA, Vanhorne JB, Mulligan LM (2001). Conservation of RET proto-oncogene splicing variants and implications for RET isoform function. Cytogenetics and Cell Genetics 95: 169-176. 7. Vanhorne JB, Myers SM, Gimm O, Eng C, von Deimling A, Mulligan LM (2001). Characterization of the GFRA2 locus and investigation of the gene in Hirschsprung disease. Hum Genet 108: 409-415.
8. Previous affiliation with the University of Ontario Institute of Technology if any (e.g. visiting professor - give dates, internal consultant, former employee, any former professor/student relationships with faculty members).
None
9. Any major blocks of time over the next 12 to 18 months when the proposed consultant may not be available.
None identified
Scraft, H.
PROGRAM: Master of Science in Applied Bioscience
1. NAME OF PROPOSED CONSULTANT: Dr. Heidi Schraft
2. RANK: Associate Professor and Canada Research Chair
3. INSTITUTION: (include mailing address, telephone and fax numbers and E-mail address)
Department of Biology Lakehead University 955 Oliver Road Thunder Bay ON CANADA P7B 5E1
email [email protected] fax (807) 346-7796 office CB 4015 (807) 343-8351 lab CB 3009 (807) 343-8735 Website: http://biology.lakeheadu.ca/wp/?pg=40
DEGREES
Dr. med. vet. (=PhD), Food Hygiene, University of Zurich, 1991 med. vet. (=BSc), Faculty of Veterinary Medicine, University of Zurich, 1985
EMPLOYMENT HISTORY
06/02 – Present Associate Professor and Canada Research Chair, Biology Dept., Lakehead University. 06/02 - 05/05 Adjunct Professor, Dept. of Food Science, University of Guelph 08/02 - 06/07 Adjunct Associate Professor, Dept. of Food Science and Technology, Dalhousie University 09/96 - 05/02 Assistant Professor, Dept. of Food Science, University of Guelph. 11/95 - 09/96 Research Associate, Dept. of Food Science, University of Guelph. 10/94 - 09/95 Postdoctoral Fellow, Dept. of Food Science, University of Guelph, supported by a fellowship of the "Commission for the Advancement of Young Scientists and Scholars", Zurich. 09/93 - 08/94 Postdoctoral Fellow, Dept. of Food Science, University of Guelph, supported by a fellowship of the "Swiss National Foundation", Zurich. 12/91 - 07/93 Senior Research Assistant, Institute for Veterinary Food Hygiene, University of Zurich. 12/85 - 11/91 Research Assistant, Institute for Veterinary Food Hygiene, University of Zurich.
Scraft, H.
HONOURS
2002- present Canada Research Chair 2001 President’s Distinguished Professor Award, University of Guelph
SCHOLARLY AND PROFESSIONAL ACTIVITIES
1999 – 2002 Program Executive Committee for the OMAFRA Food Program. 2000 – 2001 Undergraduate Coordinator and member of the Executive Committee, Dept. of Food Science, University of Guelph. 2000 – 2001 Board of Directors of the Ontario Food Protection Association. 1997 – 1999 Director of the Guelph Section of the Canadian Institute for Food Science and Technology. 1998 Member of the Organizing Committee for the 1998 Annual Meeting of the Canadian Society of Microbiologists in Guelph, Ontario.
GRADUATE COURSES
• 2005 Graduate Seminar Course, Biology, Lakehead University • 2004 Health Sciences Seminar, Guest lecture on microbial biofilms, Masters of Public Health Program, Lakehead University • 2003 Advanced Food Microbiology, Biology, Lakehead University • 2001 Principles of Food Safety and Quality Assurance, Guest lecture on microbial biofilms, Food Science, University of Guelph • 2000 Principles of Food Safety and Quality Assurance, Guest lecture on microbial biofilms, Food Science, University of Guelph • 1999 Principles of Food Safety and Quality Assurance, Guest lecture on microbial biofilms, Food Science, University of Guelph • 1998 Principles of Food Safety and Quality Assurance, Guest lecture on microbial biofilms, Food Science, University of Guelph
PUBLICATIONS
1) Life-time Summary
- Chapters in books...... 2 - Papers in refereed journals ...... 15 - Papers in refereed conference proceedings...... 3 - Technical reports...... 2 - Abstracts and/or papers read ...... 42 - Others (workshops presented, etc.):……………………………………………1
2) Details for Past Seven (7) Years
Scraft, H.
Chapters in Books: 1. H. Schraft and M.W. Griffiths. Bacillus cereus Gastroenteritis. Invited book chapter accepted for publication in: Foodborne infections and intoxications, third edition, edited by H. Riemann and D.O. Cliver. Academic Press, San Diego, CA (accepted October 1999, updated version accepted January 2004). 2. M.W. Griffiths and H. Schraft. 2002. Bacillus cereus gastroenteritis. Invited book chapter in: Foodborne diseases, second edition, edited by D.O. Cliver and H. Riemann. Elsevier Science Ltd.
Papers in Refereed Journals:
1. Chae, M.S., H. Schraft, L. Truelstrup-Hansen and R. Mackereth. Effects of physicochemical surface characteristics of Listeria monocytogenes strains on attachment to glass. Submitted to Food Microbiology December 2004. 2. Watterworth, L., E. Topp, H. Schraft and K.T. Leung. Persistence of various ERIC- Genotypes of Shiga Toxin-Producing Escherichia coli in well water. Submitted to FEMS Microbiology Letters. 3. Watterworth, L., E. Topp, H. Schraft and K.T. Leung. 2005. Multiplex PCR-DNA Probe Assay for the Detection of Pathogenic Escherichia coli. Journal of Microbiological Methods. 60: 93-105. 4. Schraft, H., and L. Watterworth. 2005. Enumeration of heterotrophs, fecal coliforms and Escherichia coli in water: comparison of 3M(TM) Petrifilm(TM) Plates with standard plating procedures. Journal of Microbiological Methods. 60: 335-342. 5. Trochimchuk, T., J. Fotheringham, E. Topp, H. Schraft, and K.T. Leung. 2003. A comparison of DNA extraction and purification methods to detect E. coli O157:H7 in cattle manure. Journal of Microbiological Methods 54: 165-175. 6. M. Chae and H. Schraft. 2001. Cell viability and architecture of Listeria monocytogenes biofilms. Food Microbiology 18: 103-112. 7. M. Chae and H. Schraft. 2000. Comparative evaluation of adhesion and biofilm formation of different Listeria monocytogenes strains. Int. J. Food Microbiol. 62: 103- 111. 8. Lin, S.F., H. Schraft, J. Odumeru and M.W. Griffiths. 1998. Identification of contamination sources of Bacillus cereus in pasteurized milk. Int. J. Food Microbiol. 43: 159-171. 9. Chumkhunthod, P., H. Schraft and M.W. Griffiths. 1998. Rapid monitoring method to assess efficacy of sanitizers against Pseudomonas putida biofilms. J. Food Prot. 61: 1043-1046. 10. Lin, S.F., H. Schraft, and M.W. Griffiths. 1998. Identification of Bacillus cereus using Fourier Transform Infrared Spectroscopy (FTIR). J. Food Prot., 61: 921-923.
Papers in Refereed Conference Proceedings: 1. Sreekumari, K.R., L. Davey, K.T. Leung, H. Schraft, A. Chen, N. Low, L. Truelstrup- Hansen, A. Paulson, and D. Pink. 2004. Microbiological and physicochemical characterisation of paper mill biofilms. Proceedings (Posters) of the International Conference Biofilms 2004: Structure and Activity of Biofilms, 24-26 October 2004 - Las Vegas, NV, USA. 2. Chae, M. and H. Schraft. 2004. Effect of two temperatures on flagellation, initial adhesion and biofilm formation of different Listeria monocytogenes strains.
Scraft, H. Proceedings (Posters) of the International Conference Biofilms 2004: Structure and Activity of Biofilms, 24-26 October 2004 - Las Vegas, NV, USA.
Technical Reports:
1. Schraft, H. 2004. Detection of Campylobacter jejuni by fluorescent in situ hybridization. Final Research Report submitted to the Food Safety Research Program of Ontario Ministry of Agriculture and Food
2. Van Duren, E., W. Howard, H. Schraft, and D. Sparling. 1998. Food ingredients in Ontario - a SWOT analysis and competitiveness assessment. Report submitted to the Food Industry Division of the Ontario Ministry of Agriculture, Food and Rural Affairs.
Abstracts and/or Papers Read:
3. Sreekumari, K., C. Cousins, L. Davey, A. Chen, K. Leung, H. Schraft, N. Low, L. Truelstrup-Hansen, A. Paulson, and D. Pink. 2005. Electrochemical and Microbiological Studies of Pulp and Paper Biofilms. Poster submitted to 207th meeting of the electrochemical society, Quebec City Convention Centre, Quebec City, Canada, May 15-20, 2005. Abstract number Z1-0630P. 4. Schraft, H. 2004. Pathogens in biofilms of food and food processing environments. Invited Presentation. Annual Meeting of the Canadian Institute of Food Science and Technology, May 16-19. Guelph, Ontario. 5. Pedri, Laura, S. Itier, H. Schraft and M. Hawton. 2004. Bacterial interaction with hydrophobic and hydrophilic interfaces. Annual March Meeting of the American Physical Society, Montreal, Quebec, March 22-26. Abstract N9.015. 6. Waddington, L. and H. Schraft. 2003. Fluorescent in situ hybridization for the culture independent detection of Campylobacter jejuni. 90th Annual Meeting of the International Association for Food Protection. New Orleans, Louisiana. August 10-13. 7. Sloan, K., L. Truelstrup-Hansen, C. Whitfield and H. Schraft. 2003. Protamine’s Antimicrobial Activity against Escherichia coli depends upon cell envelope, structure and electrostatic interactions. 90th Annual Meeting of the International Association for Food Protection. New Orleans, Louisiana. August 10-13. 8. Watterworth, L., E. Topp, H. Schraft, and K.T. Leung. 2003. Persistence of enterohemorrhagic E. coli in well water and its relatedness to ERIC-PCR genotype. 53rd Annual Meeting of the Canadian Society of Microbiologists. Laval, Quebec, May 25-29. 9. Schraft, H. 2002. Biofilm formation by foodborne pathogens. Annual Meeting of the Canadian Society of Microbiologists, Saskatoon, Saskatchewan, June 16-19. Invited Presentation. 10. Trochimchuk, T.M., H. Schraft, and K.T. Leung. 2002. Effectiveness of four DNA purification methods for manure samples. Annual Meeting of the Canadian Society of Microbiologists, Saskatoon, Saskatchewan, June 16-19. Abstract Emp25. 11. Watterworth, L.A., H. Schraft, K.T. Leung. 2002. Detection of pathogenic E. coli via a rapid multiplex PCR-DNA probe assay. Annual Meeting of the Canadian Society of Microbiologists, Saskatoon, Saskatchewan, June 16-19. Abstract Emp24.
Scraft, H.
12. Chae M.S., and H. Schraft. 2002. The effects of the physicochemical surface characteristics of seven epidemic and fourteen sporadic Listeria monocytogenes strains on adhesion to glass. Annual Meeting of IFT, Anaheim, June 2002. Abstract 46E-20 13. Schraft, H. and L.A. Watterworth. 2001. Enumeration of total heterotrophic counts and fecal coliforms in wastewater by membrane filtration: comparison of 3M™ Petrifilm™ Plates with standard plating. Annual Meeting of the Canadian Society of Microbiologists,Waterloo, ON, June 10-13. 14. Chae, M.S. and H. Schraft. 2001. Effect of temperature and motility on biofilm formation by Listeria monocytogenes. 101st ASM General Meeting, May 20-24, 2001, Orlando, Florida. 15. Shin, Y.S. and H. Schraft. 2001. Incidence of Bacillus cereus in Ontario pasteurized milk. 101st ASM General Meeting, May 20-24, 2001, Orlando, Florida. 16. Si, W., Y.S. Shin and H. Schraft. Cold adaptation of Bacillus cereus isolated from Canadian pasteurized milk. 101st ASM General Meeting, May 20-24, 2001, Orlando, Florida. 17. Schraft, H. 2001. Microbial communities – strategies for bacterial survival. Food Technology 01, Annual Meeting of the Canadian Institute of Food Technologists, June 3-6, 2001, Toronto, Canada. Invited Presentation. 18. Foong, K.K., H. Schraft and I. Britt. 2001. Controlled shelf-life study of packaged ready-to-use iceberg lettuce. Food Technology 01, Annual Meeting of the Canadian Institute of Food Technologists, June 3-6, 2001, Toronto, Canada. 19. Chae, M.S., S. A. Grant, K. Marcoux, and H. Schraft. 2000. Analysis of biofilm growth, structure, and microbial competition of Listeria monocytogenes and Pseudomonas putida in isolated and mixed culture. ASM Conference Biofilm 2000, July 2000, Big Sky, Montana 20. Tang, N., and H. Schraft. 2000. Temperature and mixed_culture effect on Campylobacter jejuni biofilm formation. Annual Meeting of IFT, Dallas, June 2000. Abstract 84_4 21. Abraham, S., H. Schraft, and M.A. Tung. 1999. Microbial colonization with biofilm formation on packaging film and vegetable tissue of ready-to-use packaged spinach. 86th Annual Meeting of IAMFES, Dearborn, MI, August 1-4. Abstract T-26. 22. Abraham, S., H. Schraft, and M.A. Tung. 1999. Microbiological and sensory quality of ready_to_use spinach stored under different temperature and packaging conditions. Annual Meeting of IFT, Chicago, July 1999. 23. Abraham, S., R. McKellar, H. Schraft, and M.A. Tung. 1999. Application of an electronic nose for the sensory evaluation of ready_to_use packaged spinach. Annual Meeting of CIFST, Kelowna, BC, June 1999. 24. Chae, M. and H. Schraft. 1999. A comparison of enumeration techniques and biofilm formation using five different strains of Listeria monocytogenes. Proc. 99th General Meeting American Soc. Microbiol., Chicago, May 30 - June 3. Abstract P-104. 25. Campbell, G.N. and H. Schraft. 1999. Studies on the adhesion properties of various foodborne lactic acid bacteria. Proc. 99th General Meeting American Soc. Microbiol., Chicago, May 30 - June 3. Abstract P-70. 26. Tang, N. and H. Schraft. 1999. Effect of basal growth media and supplements on the growth of Campylobacter jejuni. Proc. 99th General Meeting American Soc. Microbiol., Chicago, May 30 - June 3. Abstract P-96.
Scraft, H.
27. Schraft, H. and M. W. Griffiths. 1998. Polymerase chain reaction (PCR) assay for the detection of viable Cryptosporidium in foods. 85th Annual Meeting of IAMFES, Nashville, August 16-19. Invited presentation 28. Buechin, A. H. Schraft and M.W. Griffiths. 1998. Selective detection of viable Cryptosporidium parvum oocysts by PCR in food samples. 48th Annual Meeting of the Canadian Society of Microbiologists, June 14-17, Guelph, ON. 29. Smith, S.E., M.W. Griffiths and H. Schraft. 1998. Detection of Cryptosporidium parvum by PCR and strain identification through restriction enzyme analysis. 48th Annual Meeting of the Canadian Society of Microbiologists, June 14-17, Guelph, ON.
Others:
1. Cooper, K. and H. Schraft. 1998. Biofilms – a time bomb in your plant? Meat & Poultry. September 1998: 58-59.
Previous affiliation with the University if any
None
Any major blocks of time over the next 12 to 18 months when the proposed consultant may not be available.
None identified
Van Der Kraak - CV Page 1 of 4
RESUME FOR PROPOSED CONSULTANT
PROGRAM: MSc in Applied Bioscience
1. NAME OF PROPOSED CONSULTANT: Dr. Glen Van Der Kraak
2. RANK: Professor and Associate Dean of Research, College of Biological Science
3. INSTITUTION: (include mailing address, telephone and fax numbers, E-mail address and, where available, the URL to the prospective consultant's web site.)
UNIVERSITY OF GUELPH GUELPH, ON N1G 2W1
Tel: 519-824-4120, ext. 53424 Fax: 519-767-1656 Email: [email protected]
4.
DEGREE UNIVERSITY DATE GRANTED B. Sc. (Hons.) Manitoba 1976 M.Sc. Manitoba 1979 Ph.D. British Columbia 1984
5. AREA(S) OF SPECIALIZATION: (relate this to those offered by the program being appraised).
Dr. Van Der Kraak is a reproductive physiologist who studies fish as the primary research model. One aspect of his research is directed at understanding the hormonal factors which control the selection, growth and differentiation of ovarian follicles. He is also very active in the area of reproductive toxicology. He studies how the individual chemicals and complex mixtures (pulp mill and sewage effluents, agricultural runoff) impact upon hormone systems controlling reproductive development in fish.
6. Experience/Expertise relevant to service as a consultant (e.g. membership on editorial boards, administrative experience, academic recognition). A short statement regarding the appropriateness of the nominee as a consultant for this program would help the committee. Assistant Professor July 1, 1987-1993 Associate Professor July 1, 1993 -1997 Professor July 1, 1997 - present Chair of Zoology Department July 1, 2000 – December 31, 2003 Associate Dean of Research November 1, 2003 – present (5 year term) NSERC University Research Fellow July, 1 1987 - June 30, 1997 Core Member Institute of Ichthyology 1990 to present Director Institute of Ichthyology July 1996 to August 2000 Adjunct Professor, Univ. of Waterloo July 1994 - present Van Der Kraak - CV Page 2 of 4
Recent Professional Activities
Editorial Board: Environmental Toxicology: 1999-present
Editorial Board: General and Comparative Endocrinology 2001-present.
Editorial Board: Comparative Biochemistry and Physiology: 2002-present
Member National Steering Committee EM-Com: 2001-present. (An internet based information resource about endocrine modulating substances.) http://www.emcom.ca
Member NSERC Integrative Animal Biology Grant Selection Committee: 2001-2004. (Co-Chair 2002-3) Chair (2003-2004).
Member United States Environmental Protection Agency Endocrine Methods Validation Sub- committee: 2001-2003.
Steering Committee: Workshop on environmental assessment of health and personal care products and pharmaceutical products in the Canadian Environment, Niagara on the lake February 24-27, 2002.
Member Scientific Program Committee (August 2000- present): 7th International Symposium on the reproductive physiology of fish. Mie, Japan, May 18-23, 2003.
Member Scientific Program Committee: 5th International Symposium on Fish Endocrinology. Castellón, Spain, September 5 to 9, 2004.
Member: Peer review panel: Computational toxicology and endocrine disruptors: US Environmental Protection Agency, May 10-11, 2004.
Member Peer review panel: Board of Scientific Counselors: Endocrine Disruptors Program US Environmental Protection Agency, December 13-15, 2004.
Member United States Environmental Protection Agency Endocrine Methods Validation Committee: April 2005-present.
7. Recent scholarly activity (if possible cite 3 to 5 recent publications giving title, date, kind of publication, journal, or publisher if a book).
LIFETIME PUBLICATIONS - GLEN VAN DER KRAAK 1. Papers published in journals: 149 2. Books and Chapters in Books: 19 3. Refereed Conference Proceedings: 53 4. Published non-Refereed Conference Proceedings: 12 5. Technical Reports: 3 6. Conference Abstracts: not reported
Van Der Kraak - CV Page 3 of 4 Books and Chapters in books
C.19. Alsop, D., G.J. Van Der Kraak, S. B. Brown and J. G. Eales. 2005. The biology and toxicology of retinoids in fish. Biochemistry and Molecular Biology of Fishes, 6; Environmental Toxicology, T.P. Mommsen and T. Moon, eds. pp. 413-428.
C.18. MacLatchy, D.M., K. L. Gormley, R.E.M. Ibey, R.L. Sharpe, K. S. Shaughnessey, S.C. Courtenay, M.G. Dube and G. Van Der Kraak. A short term Mummichog (Fundulus heteroclitus) bioassay to assess endocrine responses to hormone-active compounds and mixtures. In Techniques in Aquatic Toxicology Vol. 2 G. Ostrander, Ed. (Accepted March 2004; 68 typed p; 2 Figs).
C. 17. Wood, A.W., D.M. Jans and G. Van Der Kraak. 2005. Cell death; investigation and application in fish toxicology. Biochemistry and Molecular Biology of Fishes, 6; Environmental Toxicology, T.P. Mommsen and T. Moon, eds. pp. 303-328.
Papers published in journals
149. Boudreau,M., S.C. Courtenay, D.L. MacLatchy, C.H. Bérubé, L.M. Hewitt, and G.J. Van Der Kraak. 2005. Morphological abnormalities during early life development of the estuarine mummichog (Fundulus heteroclitus), as an indicator of androgenic and anti-androgenic endocrine disruption. Aquatic Toxicology 71: 357-369.
148. Bubenik, G.A., K.V. Miller, A.L. Lister, D.A. Osborn. L. Bartos, and G.J. Van Der Kraak. 2005. Testosterone and estradiol concentrations in serum, velvet, skin and growing antler bone of male white-tailed deer. Journal of Experimental Biology. 303A: 186-192.
147. Coady K.K., M.B. Murphy, D.L Villeneuve, M. Hecker, J.A. Carr, K.R. Solomon, G. Van Der Kraak, E.E. Smith, R.J. Kendall, and J.P. Giesy. Effects of atrazine on metamorphosis, growth, laryngeal and gonadal development, aromatase activity, and sex steroid concentrations in Xenopus laevis. Ecotoxicology and Environmental Safety. In press.
146. Cooke, S.J., Crossin, G.T., Patterson, D., English, K.K., Hinch, S.G., Young, J.L., Alexander, R.F., Healey, M.C., Van Der Kraak, G. and Farrell A.P. 2005. Coupling non-invasive physiological assessments with telemetry to understand inter-individual variation in behaviour and survivorship of fish: development and validation of a technique. Journal of Fish Biology (accepted February 2005).
145. Du Preez LH, Jansen van Rensburg PJ, Jooste AM, Carr JA, Giesy JP, Gross TS, Kendall RJ, Smith EE, Van Der Kraak G, Solomon KR. 2005. Seasonal exposures to triazine and other pesticides in surface waters in the western Highveld corn-production region in South Africa. Environmental Pollution 135: 131-141.
144. Du Preez LH, Solomon KR, Carr JA, Giesy JP, Gross TS, Kendall RJ, Smith EE, Van Der Kraak GJ, Weldon C. 2005. Population structure characterization of the clawed frog (Xenopus laevis) in maize-growing versus non-maize-growing areas in South Africa. African Journal of Herpetology in press.
143. Hecker M., W.J. Kim, J.W. Park, M.B. Murphy, D.L. Villeneuve, K.K. Coady, P.D. Jones, K.R. Solomon, G. Van Der Kraak, J.A. Carr, E.E. Smith, L. du Preez, R.J. Kendall and J.P. Giesy. 2005. Effects of estradiol and atrazine on plasma sex steroid concentrations, gonadal aromatase activity and ultrastructure of the testis in Xenopus laevis. Aquatic Toxicology Accepted January 2005. Van Der Kraak - CV Page 4 of 4
8. Previous affiliation with the University of Ontario Institute of Technology if any (e.g. visiting professor - give dates, internal consultant, former employee, any former professor/student relationships with faculty members).
None
9. Any major blocks of time over the next 12 to 18 months when the proposed consultant may not be available.
None indicated