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SUPPLEMENTAL DIGITAL CONTENT (SDC) SDC, Appendix SUPPLEMENTAL DIGITAL CONTENT (SDC) SDC, Appendix Fold Change p‐value ID Symbol Entrez Gene Name ‐1.751 3.93E‐03 STAP1 STAP1 signal transducing adaptor family member 1 ‐1.705 3.05E‐03 QPCT QPCT (includes EG:25797) glutaminyl‐peptide cyclotransferase ‐1.667 9.29E‐04 FAM30A FAM30A family with sequence similarity 30, member A ‐1.591 1.50E‐04 ZNF480 ZNF480 zinc finger protein 480 ‐1.523 2.75E‐04 KCNK10 KCNK10 potassium channel, subfamily K, member 10 ‐1.502 5.72E‐04 KCTD18 KCTD18 potassium channel tetramerisation domain containing 18 ‐1.498 3.48E‐04 DOC2B DOC2B double C2‐like domains, beta ‐1.470 1.16E‐04 FLYWCH2 FLYWCH2 FLYWCH family member 2 ‐1.460 4.30E‐03 APOOL APOOL apolipoprotein O‐like ‐1.417 6.56E‐04 NANP NANP N‐acetylneuraminic acid phosphatase ‐1.395 4.57E‐04 CLN8 CLN8 ceroid‐lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) ‐1.395 1.97E‐03 KIAA2026 KIAA2026 KIAA2026 ‐1.378 7.66E‐04 GJD4 GJD4 gap junction protein, delta 4, 40.1kDa ‐1.371 3.00E‐03 APPL1 APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 ‐1.350 6.05E‐04 ZNF12 ZNF12 zinc finger protein 12 ‐1.346 3.94E‐04 DGKZ DGKZ diacylglycerol kinase, zeta 104kDa ‐1.344 2.53E‐03 SMYD3 SMYD3 SET and MYND domain containing 3 ‐1.337 1.72E‐03 POU2AF1 POU2AF1 POU class 2 associating factor 1 ‐1.336 4.39E‐03 PDE6G PDE6G phosphodiesterase 6G, cGMP‐specific, rod, gamma ‐1.333 2.31E‐03 C12orf26 C12ORF26 chromosome 12 open reading frame 26 ‐1.322 4.26E‐03 MTMR3 MTMR3 myotubularin related protein 3 ‐1.306 3.31E‐03 HMHB1 HMHB1 histocompatibility (minor) HB‐1 ‐1.301 1.00E‐03 HSD17B1 HSD17B1 hydroxysteroid (17‐beta) dehydrogenase 1 ‐1.297 4.82E‐03 FCN1 FCN1 ficolin (collagen/fibrinogen domain containing) 1 SUPPLEMENTAL DIGITAL CONTENT (SDC) ‐1.296 4.39E‐03 MARCO MARCO macrophage receptor with collagenous structure ‐1.290 2.63E‐03 SLC25A4 SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 ‐1.289 1.42E‐03 RPL22 RPL22 ribosomal protein L22 ‐1.288 1.86E‐03 REV1 REV1 REV1 homolog (S. cerevisiae) ‐1.286 2.99E‐04 CLN8 CLN8 ceroid‐lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) ‐1.282 1.19E‐03 BOLA1 BOLA1 bolA homolog 1 (E. coli) ‐1.281 1.01E‐03 ATG16L2 ATG16L2 ATG16 autophagy related 16‐like 2 (S. cerevisiae) ‐1.280 3.54E‐03 GNG10 GNG10 guanine nucleotide binding protein (G protein), gamma 10 ‐1.279 2.02E‐03 ALKBH3 ALKBH3 alkB, alkylation repair homolog 3 (E. coli) ‐1.279 4.51E‐03 TRIM17 TRIM17 tripartite motif‐containing 17 ‐1.275 4.91E‐04 CCR10 CCR10 chemokine (C‐C motif) receptor 10 ‐1.274 8.45E‐05 SLAIN2 SLAIN2 SLAIN motif family, member 2 ‐1.272 1.59E‐03 C9orf7 C9ORF7 chromosome 9 open reading frame 7 ‐1.272 4.29E‐03 IGLL1 IGLL1 immunoglobulin lambda‐like polypeptide 1 ‐1.271 1.14E‐03 CCT6B CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) ‐1.266 1.64E‐03 C14orf159 C14ORF159 chromosome 14 open reading frame 159 ‐1.264 1.40E‐03 ZNF621 ZNF621 zinc finger protein 621 ‐1.257 1.81E‐03 C21orf123 NCRNA00175 non‐protein coding RNA 175 ‐1.252 5.65E‐04 CLCNKA CLCNKA chloride channel Ka ‐1.251 2.92E‐03 WBSCR28 WBSCR28 Williams‐Beuren syndrome chromosome region 28 ‐1.243 2.96E‐03 ANKLE1 ANKLE1 ankyrin repeat and LEM domain containing 1 ‐1.237 3.59E‐03 ATPAF1 ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 ‐1.237 3.34E‐03 CHST12 CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 ‐1.234 2.70E‐03 POU6F2 POU6F2 POU class 6 homeobox 2 ‐1.233 1.55E‐03 C14orf177 C14ORF177 chromosome 14 open reading frame 177 ‐1.233 2.71E‐03 C6orf25 C6ORF25 chromosome 6 open reading frame 25 ‐1.229 2.87E‐03 ATP2B3 ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 SUPPLEMENTAL DIGITAL CONTENT (SDC) ‐1.228 2.42E‐04 LOXL3 LOXL3 lysyl oxidase‐like 3 ‐1.226 3.18E‐03 CLEC4F CLEC4F C‐type lectin domain family 4, member F ‐1.223 3.80E‐03 TAF8 TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)‐associated factor, 43kDa ‐1.223 2.78E‐03 ZGPAT ZGPAT zinc finger, CCCH‐type with G patch domain ‐1.221 4.92E‐03 CCDC153 CCDC153 coiled‐coil domain containing 153 ‐1.216 2.92E‐03 C19orf34 C19ORF34 chromosome 19 open reading frame 34 ‐1.212 3.02E‐03 CDK3 CDK3 cyclin‐dependent kinase 3 ‐1.212 4.66E‐03 COL8A2 COL8A2 collagen, type VIII, alpha 2 ‐1.210 3.76E‐03 SH3TC1 SH3TC1 SH3 domain and tetratricopeptide repeats 1 ‐1.209 3.27E‐03 UXT UXT ubiquitously‐expressed transcript ‐1.206 3.89E‐03 RASL10A RASL10A RAS‐like, family 10, member A ‐1.205 3.77E‐04 AIPL1 AIPL1 aryl hydrocarbon receptor interacting protein‐like 1 ‐1.204 4.23E‐03 BAG1 BAG1 BCL2‐associated athanogene ‐1.203 1.73E‐03 GPR62 GPR62 G protein‐coupled receptor 62 ‐1.202 3.84E‐03 TTC31 TTC31 tetratricopeptide repeat domain 31 1.202 3.27E‐03 ATP13A2 ATP13A2 ATPase type 13A2 1.202 1.84E‐04 CD200R1L CD200R1L CD200 receptor 1‐like 1.213 1.74E‐03 UBE2J2 UBE2J2 ubiquitin‐conjugating enzyme E2, J2 (UBC6 homolog, yeast) 1.213 1.58E‐03 WDR69 WDR69 (includes EG:164781) WD repeat domain 69 1.217 4.72E‐03 HIST1H2AL HIST1H2AL (includes EG:8332) histone cluster 1, H2al 1.221 2.22E‐03 PRAMEF15 PRAMEF15 PRAME family member 15 1.221 8.17E‐04 SAP30BP SAP30BP SAP30 binding protein 1.225 1.26E‐03 COPS7B COPS7B COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) 1.228 2.43E‐03 ALDOA ALDOA aldolase A, fructose‐bisphosphate 1.228 1.60E‐03 F3 F3 coagulation factor III (thromboplastin, tissue factor) 1.229 4.11E‐03 RS1 RS1 (includes EG:6247) retinoschisin 1 1.230 4.49E‐03 POLR2F POLR2F polymerase (RNA) II (DNA directed) polypeptide F SUPPLEMENTAL DIGITAL CONTENT (SDC) 1.233 6.51E‐04 PRAMEF15 PRAMEF15 PRAME family member 15 1.237 9.21E‐04 C11orf40 C11ORF40 chromosome 11 open reading frame 40 1.252 4.09E‐03 STAT6 STAT6 signal transducer and activator of transcription 6, interleukin‐4 induced 1.252 2.11E‐03 ZCCHC5 ZCCHC5 zinc finger, CCHC domain containing 5 1.258 3.06E‐03 UPK1B UPK1B uroplakin 1B 1.259 4.07E‐03 SLC7A14 SLC7A14 solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 1.263 9.45E‐04 TARS2 TARS2 threonyl‐tRNA synthetase 2, mitochondrial (putative) 1.266 4.11E‐03 USF1 USF1 upstream transcription factor 1 1.270 2.68E‐03 SNRPN SNRPN small nuclear ribonucleoprotein polypeptide N 1.281 5.00E‐04 C11orf88 C11ORF88 chromosome 11 open reading frame 88 1.298 2.35E‐03 IL4 IL4 interleukin 4 1.300 1.72E‐03 HIF1AN HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 1.304 2.45E‐03 SNRPN SNRPN small nuclear ribonucleoprotein polypeptide N 1.311 1.73E‐03 ACOT12 ACOT12 acyl‐CoA thioesterase 12 1.314 4.87E‐03 PRAMEF6 PRAMEF6 PRAME family member 6 1.316 2.11E‐03 IFNA14 IFNA14 interferon, alpha 14 1.324 4.36E‐03 HIST1H2BE HIST1H2BE histone cluster 1, H2be 1.329 1.57E‐04 IRX4 IRX4 iroquois homeobox 4 1.331 3.75E‐03 WBP2NL WBP2NL WBP2 N‐terminal like 1.347 2.78E‐04 OR2M3 OR2M3 olfactory receptor, family 2, subfamily M, member 3 1.357 1.39E‐03 FANCB FANCB Fanconi anemia, complementation group B 1.358 3.74E‐03 MCM7 MCM7 minichromosome maintenance complex component 7 1.393 4.42E‐04 HIST1H3D HIST1H3D histone cluster 1, H3d 1.404 9.07E‐04 OR10H5 OR10H5 olfactory receptor, family 10, subfamily H, member 5 1.515 1.36E‐03 SNRPN SNRPN small nuclear ribonucleoprotein polypeptide N 1.567 1.22E‐03 ZNF705A ZNF705A zinc finger protein 705A 1.744 2.55E‐03 SNRPN SNRPN small nuclear ribonucleoprotein polypeptide N SUPPLEMENTAL DIGITAL CONTENT (SDC) 1.752 3.69E‐03 LIPN LIPN lipase, family member N 1.788 9.68E‐04 PSG2 PSG2 pregnancy specific beta‐1‐glycoprotein 2 .
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