Supplementary appendix This appendix formed part of the original submission. We post it as supplied by the authors.

Supplement to: Zhang L, Zhong P, Zhai X, et al. Open letter from Chinese HIV professionals on human genome editing. Lancet 2018; published online Nov 30. http://dx.doi.org/10.1016/S0140-6736(18)33082-4.

Signatories Open letter from Chinese HIV professionals on human genome editing

Linqi Zhang, Tsinghua University AIDS Research Center Ping Zhong, Shanghai Institute of Preventive Medicine Xiaomei Zhai, Center for Bioethics, Chinese academy of medical sciences Yiming Shao, Chinese Center for Disease Control and Prevention Shan Lu, University of Massachusetts School of Medicine Qinxue Hu, Wuhan Institute of Virology, CAS Xiang He, Guangdong Provincial Institute of Public Health Tongqing Zhou, Structural Bioinformatics Section at Vaccine Research Center, NIAID/NIH Shanlv Liu, The Ohio State University Haitao Hu, Department of Medicine, University of Texas/ Sealy Center for Vaccine Development Binhua Ling, Tulane University School Lihong Liu, Rockefeller University USA Fan Wu, Fudan University Bin Su, Beijing YouAn Hospital, Capital Medical University Xiaoxu Han, The First Hospital of China Medical University Tong Zhang, Beijing YouAn Hospital, Capital Medical University Min Wang, Changsha AIDS Medical Research Institute Jian Wang, Chinese Academy of Chinese Medical Science Jinghe Huang, Fudan University Ling Chen, Guangzhou Institute of Biomedicine and Health, CAS Xueling Wu, Rockefeller University USA Wei Jiang, Medical University of South Carolina Hui Zeng, Beijing Ditan Hospital Capital Medical University Hui Zhang, Sun Yat-Sen University Xiejie Chen, The Eighth People's Hospital of Guangzhou Susu Liao, Peking Union Medical College Qingxia Zhao, the Sixth People's Hospital of Zhengzhou Hui Wang, the Third People's Hospital of Shenzhen Chuan Qin, Chinese Academy of Medical Sciences-Chinese Peking Union Medical College Chunsheng Dong, Suzhou University Xia Jin, Chinese Academy of Sciences Fujie Zhang, Beijing Ditan Hospital Capital Medical University Zhiwei Wu, Nanjing University Huimin Yan, Wuhan Institute of Virology, CAS Ying Wang, Shanghai Municipal Center for Disease Control and Prevention Weipin Cai, Guangzhou Eighth People's Hospital Zhiwei Chen，AIDS Institute of Hong Kong University Linghua Li，Guangzhou Eighth People's Hospital Deyin Guo，Medical College of Sun Yat-sen University Shuwen Liu，Southern Medical University 1

Yuxian He, Chinese Academy of Medical Sciences, Peking union Medical college Wei Hou, Wuhan University School of Basic Medical Science Kai Deng, Sun Yat-sen School of Medicine, SYSU Yongtang Zheng, Kunming Institute of Zoology Ruolei Xin, Beijing Centers for Diseases Control and Prevention Guiju Gao, Beijing Ditan Hospital Capital Medical University Rongge Yang, Wuhan Institute of Virology, Chinese Academy of Sciences Fei Guo, Institute of Medical Biology Chinese Academy of Medical Sciences Yile Xue, Shanghai Municipal Center for Disease Control & Prevention Hui Xing, National Center for AIDS/STD Control & Prevention, China CDC Wenyan Zhang, The Institute of HIV/AIDS, the First Hospital of Jilin University Zheng Zhang, Shenzhen Third People's Hospital Hongzhou Lu, Shanghai Public Health Clinical Center Jianhua Li, Yunnan Institute of Drug Dependence Prevention and Control Nanping Wu, Zhejiang University Lu Lu, Fudan University Jin Zhao, Shenzhen Center for Disease Control and Prevention Jianjun Wu, Anhui Center for Disease Control and Prevention Zhefeng Meng, Minhang Hospital affiliated to Fudan University Xi Jin, Chinese Center for Disease Control and Prevention Ailing Wang, Chinese Center for Disease Control and Prevention Hua Liang, Chinese Center for Disease Control and Prevention Yiqun Kuang, Henan University Shujia Liang, Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Panpan Zhou, Comprehensive AIDS research center of Tsinghua University Fei Gao, Comprehensive AIDS Research Center of Tsinghua University Jianping Xie, Institute of Modern Biomedicine, College of Life Sciences, Southwest University, Taisheng Li, Peking Union Medical College Sisi Shan, Comprehensive AIDS Research Center of Tsinghua University Bin Li, School of Medicine, Shanghai Jiaotong University Aihua Zheng, Institute of zoology, Chinese Academy of Sciences Bin Wang, The School of Basic Medical Sciences, Fudan University Hongkui Deng, School of Life Sciences, Peking University Shibo Jiang, Institute of Pathogenic Microbiology, Fudan University Jianping Xie, School of Life Sciences, Southwest University Yong Liao, The Second Affiliated Hospital of Chongqing Medical University Hongxin Deng, West China Hospital, Sichuan University Yangyang Li, Comprehensive AIDS Research Center, Tsinghua University Qian Wang, Comprehensive AIDS Research Center, Tsinghua University Qingtai Liang, Comprehensive AIDS Research Center, Tsinghua University Caijun Sun, Sun Yat-sen University Yanan Zuo, Comprehensive AIDS Research Center, Tsinghua University Wenxu Jia, Comprehensive AIDS Research Center, Tsinghua University 2

Mingxi Li, Comprehensive AIDS Research Center, Tsinghua University Xuejun Chen, Center for Vaccine Research, National Institutes of Health Shixia Wang, Department of Nucleic Acid Vaccine, School of Medicine, University of Massachusetts Manhong Jia, Center for Disease Control and Prevention, Yunnan Province Qi Zhang, Comprehensive AIDS Research Center, Tsinghua University Xianghui Yu, National Engineering Laboratory of AIDS Vaccine, Jilin University Feng Gao, National Engineering Laboratory of AIDS Vaccine, Jilin University Zhiliang Hu, Nanjing No. 2 Hospital Guo Wei, AIDS Surgery Center, Chengdu Public Health Clinical Medical Center Yu Zhang, Urology Center, Beijing You'An Hospital, Capital Medical University Jueren Lou, Shanghai Institute of Biological Products Xuemei Zhang, Chengdu Institute of Biological Products Tianlei Ying, Fudan University Han Wang, Comprehensive AIDS Research Center, Tsinghua University Mengqi Fang, Comprehensive AIDS Research Center, Tsinghua University. Xiaodi Liu, Comprehensive AIDS Research Center, Tsinghua University Zining Zhang, China Medical University Hai Jiang, Institute of Biochemical Sciences, Chinese Academy of Sciences Hongxin Zhao, Beijing Ditan Hospital Yaokai Chen, Chongqing Public Health Medical Treatment Center Hua Wang, Beckman Institute, City of Hope National Medical Center, USA Bingjie Shi, School of Life Sciences, Beijing University of Chinese Medicine Huan Wang, School of Medicine, Tsinghua University Ying Wang, School of Medicine, Tsinghua University Yuanlong Lin, the Forth Affiliated Hospital of Harbin Medical University Xuanling Shi, Comprehensive AIDS research center, Tsinghua University Yong Qing, Anorectal Dermatology Department, Chengdu Anorectal Hospital Lifeng Xu, Conchino Biology Tongtong Yang, Chengdu Public Health Clinical Medical Center Rui Gong, Wuhan Institute of Virology, CAS Hongxin Deng, West China Hospital, Sichuan University Xiaoyuan Xu, Peking University First Hospital Jihua Fu, Shandong Center for Disease Control and Prevention Xuefeng Yu, Conchino Biology Jianhua Yu, Hangzhou Sixth People's Hospital Jingmeiqi Ye, College of Life Sciences, Tsinghua University Haixu Chen, Second Medical Center of PLA General Hospital Xianqiong Pang, People's Hospital of Xichong County, Sichuan Province Su Jin, College of Life Sciences, Tsinghua University Jing An, Capital Medical University Shasha Shi, Comprehensive AIDS research center, Tsinghua University Jinliang Li, National Research Center of Anti-HIV Drug Engineering Technology Hao Wu, College of Life Sciences, Tsinghua University 3

Manxuan Zhou, College of Life Sciences, Tsinghua University Lijun Sun, Beijing YouAn Hospital Affiliated to Capital Medical University Wei Yue, Lanzhou University First Hospital Teng Zuo, Harvard Medical College, USA Liwei Jiang, Harvard Medical College, USA Xia Li, Yunnan AIDS Care Center Qihan Li, Chinese Academy of Medical Sciences Shenghua He, Chengdu Public Health Clinical Medical Center Fuxiang Wang, Shenzhen Third Hospital Ruoke Wang, Comprehensive AIDS Research Center, Tsinghua University Bo Liu, Liaoning Anshan Infectious Diseases Hospital Yongmao Huang, Affiliated Hospital of Southwest Medical University Zhengyin Liu, Peking Union Medical College Hospital Xiaojie Huang, Beijing You'An Hospital affiliated to Capital Medical University Jianjun Yue, The Fourth People's Hospital of Taiyuan, Department of infectious diseases Jianyun Wang, Hospital of Infectious Diseases of Gansu province, Xiaoli Xin, Shenyang Infectious Disease Hospital, Care department Lianguo Ruan, Wuhan JinYinTan Hospital Hong Zhang, Anshan Infectious Diseases Hospital Bo Song, The Fourth Affiliated Hospital of Harbin Medical University Shouxin Chen, TieLing Infectious Diseases Hospital Xiuling Feng, Henan Infectious Diseases Hospital Wei Zhou, Nanchang University, Professor Ying Shen, Qiqihar Seventh Hospital Yan He, Central South University Jin Li, Changchun Infectious Diseases Hospital Liangshuang Jiang, Chengdu Public Health Clinical Medical Center Biao Zhu, The First Affiliated Hospital Zhejiang University

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