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Introducing TM - @- — @ IODOHIPPURATE0 :.,.@@,123INJECTiON Normal Transp@nt Renogram1 -. HighDetectorEfficiency 0• 9 P9999,9999 lodohippurateSodiumI 131Injection,0.15mCi LowCountRate Low DetectorEfficiency NEPHROFLOWprovidesbettercountingstatisticsandhigherdatadensity. ‘Reference:Dataon file. Medi-Ptiysics, Inc.. Richmond. CA ‘NaHTIftrvstaI . Particularly useful in obstructed patients . Slight advantage in photon intensity . Major advantage in ¼inch crystal efticiency •Imagingshouldbe performedas closeto calibrationtime as possible 744 b4@ 514 41) :so 20 14) IERCENT ABS@RV1I()N ComparisonofI 123andI 131 Characteristic 1123 1131 Modeof Decay Electroncapture Beta Half-Life 13.2hours 193hours PrincipalGamma Energy(keV) 159 364 Intensity 84% 82% Half-Valuelayer,lead,cm 0.037 0.24 DetectionEfficiency: ¼―Nal (TI ) crystal 74.5% 22.5% NEPHROFLOW'@ IODOHIPPURATESODIUMI 123INJECTION Forcomplstspse.cdblng InformationconsultpackagsInsert,abrlefsummaryof whichfollows: DESCRIPTION:IodohippurateSodiumi l23lnjection issupplied asasterile, apyrogenic, Radlopharmaceuticals should be used only by physicians who are qualified by training aqueous,isotonicsalinesolutionfor intravenousadministration.Eachmilliliterof the and experience in the safe use and handling of radsonuclidesand whose experience and solutioncontains37 megabecquerels(1 mtlhcurie)lodohippurateSodiumI 123 at training havebeenapproved bytheapproprlategovemmentagencyauthorizedtollcense calibrationtime, 2 milligramslodohippurateSodium,I percentbenzylalCOhOl(as a the useofradionuclides. preservative). 9 milligrams per milliliter sodium chloride for fsotonfcfty, and up to 0.1 Carc!nogenesls. Mutagenesis, Impairment of Fertility percent ethanol. The solution a buffered with sodium phosphate and the pH a adjusted No long term animal Studies have been performed to evaluate carcinogenic potential. to 7.0-8.5 wIth sodium hydroxide or hydrOchlOricacid. The radionudlidèccomposttion at mutagenicity potential, orwhetherlodohippurate Sodium I 123affectsfertility In males or calibration time is not less than 94.7 percent I 123. not more than 4.8 percent I 124, and not more than 0.5 percent aDothers (1125, I 126, I 130, Na 24. Te 121).The radionuclidic females. composition at expiration time Is not less than 85.5 percent I 123, not more than 12.9 PregnancyCategoryC percent I 124.and not more than I .6 percent all others. AnimalreporductionstudieshavenotbeencOnduCtedwiththisdrug.It Isalsonotknown whether lodohippurate Sodium I 123 can cause fetal harm when administered to a INDICATIONS AND USAGE: lodohippurate Sodium I 123 Injection is a diagnostic aid in determining renal function, renal blood flow. and urinary tractobstructlon, and as a renal pregnant woman, orcan affect reproductivecapaclty. lodohlppurate Sodium I 123should ImagIngagent. be given to a pregnant woman onlyifclearly needed. Ideally, examinations using radlopharmaceuticals. especially those elective In nature. in CONTRAINDICAT1ONS:NoneKnown. women ofchildbearing capabilityshould be performed during thefirst few (approximately WARNINGS: NoneKnown. ten)daysfollowlng the onset of menses. PRECAUTIONS: NursingMothers General Since lodine@123Is excreted in human milk, formula.feedlng should be substituted for The contents of the vial are radioactive. Adequate shieldIng of the preparation must be breast feeding Itthe agent must be administered tothe mother during lactation. maintained at all limes. PediatricUse Do not useaftertheexpiration tlmeanddate(24hoursaftercallbrationtlme)stated on the SafetyandeffectivenessInchildrenhavenotbeenestablished. @bei ADVERSE REACTIONS:Aswlthallorganlciodinecontainingcompounds,thepossibility The prescribed Iodohippurate SodIum I 123 dose should be administered as soon as of allergicreactionsmust be kept In mind. Nausea, vomiting.and faintinghave been practical from the time of receipt of the product (I.e.. as close to calIbration time as reported in conjunction with the administration oflodohippurate Sodium I 123. oossiblallnorderto mlnimlzethefractionotradlatlonexoosure duetorelativeincrease of HOWSUPPLIED: lodohippurateSodiumI 123InjectionIssuppliedinnominal3.5 mlvials as a sterile. nonpyrogenic.aqueous.Isotonicsalinesolutionfor intravenousinjection. Iodohlppurat. Sodium I 123.sawell asotherradloactiv.drugs. mustbe handledwlthcare Eachmlllllltercontains37 megabecquerels(1mIlllcurle)oflodohippurateSodiumI 123at and appropriatesafetymeasuresshouldbe usedto minimizeradiationexposureto calibration time. clinical personnel. Careshouldalsobetakentomlmlnlze radlatlonexposuretothepatient lila available,Inindividualvials,inthefollowlngsizes: conslstentwfth proper Patient management. MPI CatalOgNo.2041;1 mland37 megabcquerels(1 mCI)pervial MPI CatalogNo.2042; 2 mland74megabecquerels(2mCI)pervial Vialsare packagedinIndividualleadshieldswithplasticoutercontainer. CircleReaderServiceNo.1 bIORE FORLESS! RPDIOISOTOPE RECORD Date: Jul 16, 1984 Time 8:11 P.M. Isotope: Tc—99m Sam@ie0 1 Pctivit.tl: 798. mCi Uoiume 28.8 ml Ccnc: 39.9 mCA'ml 99Mo: 27.8 L*:;@ Mo/Tc: .834 uCt'mCi RPDIOISOTOPE RECORD @dte: Jul 16, 1984 @ I re: 8:12 P.M. - . Isovope: Tc-99m Sam@1e 0 Dose: 5.08 inCA Isotope Deca'@Chart COMP-U-CALM8:3e P.M. 38.5 aCi/mi A Puny-Computerized Radioisotope Calibrator .13 ml Mo: .836 uCi'mCA That You and YouxBudget Will Appreciate! 9:@gP.M. 36.3 mC@;m1 .14 ml COMP-U-CALTMGiVESYOUMORE Mo: .@38 uCi/nt@ 9:30 P.M. 34.3 mCi/mi U Providesa printedrecordofdate,time,isotopeactivity, .15 ml concentration. syringe volume and assay results @e4euC@@/A@uCi/mCA U Calculatesand printsoutthe concentrationand volumeforany desireddose, corrected for decay for a whole day, or for a single dose, as desired. Performs complete 99Mo assay on 99!T1Tcsamples. COMP-U-CALTMGiVESYOUMOREFORLESS. ..ONLY$4,9QQ Other Price/Performance Values DELUXE ISOTOPE CAL/PADTMII CALIEI@ATOR Offers a fast. accurate Provides the budget means of measuring the conscious lab with an activity of radioisotope economical calibrator doses. system that's reliable. too. ONLY$3 975 ONLY$ 1,495 nc.To TMVictoreen@ find out how to get more for less, 3541-B.NUCLEARASSOCIATES100%call or write for det@Is. Request Bulletin Divisionof VICTOREEN, INC. SATISFACTION GUARANTEED! iooVOICEROAD Ifforany reason you are not completely satisfiedwith a Nucleai Associates CARLE PLACE, NY 11514-1593 741-6360I JA (516) @ product it may be returned within 30 days of shipment for full credit.VICTOREEN A Subsidiaryof Sheller-Globe THEPPICE/PEPSOPMANCELEADERINRADIOISOTOPECALIBRATORS1 CircleReaderServIceNo.2 IiHP@[email protected]@Iapiapiopio@ Now there is a practical and economical way to meet your \ nuclear medicine requirements. NPI, the originator of Unidose pioneered the way with individual dosages of prescribed radiopharmaceuticals supplied only when you need them. Unidose is only one NPI innovation with the future in mind. No longer must you worry about handling and storing large inventories of radioactive @ materials and waste. You can meet today's demands for cost containment with Unidose. And its safety factor goes a @ long way towards meeting ALARA goals. .‘@ NPI service centers supply your diagnostic imaging needs on demand, 24 hours a day from 47 centralized radiopharmacies nationwide. Quality _@__\ radiopharmaceuticals coupled with NPI'Sradiation safety services and accessory products ensure that future advances in nuclear medicine reach the world of practical application. Meeting your requirements now and for the future, Nuclear Pharmacy Incorporated. I -800-821-0547 4272 Balloon Park Road. NE/Albuquerque, NM 87109 Circle Reader Service No 3 AoouOal..2001 roili0000flde doseoolibrotor XLIVREX.! -i 1 portableXenondelivery andtrappingsystem forusein lungventilation studiesinvolving Xenon133and Xenon127 Circle Reader Service No 5 @ . @. -@-- @1HpIH@IHpIHpIHpIHpIHpIHpIHpIHpIHpIHpIHpIHpIHpIHpIHpIHpIHPInpiHi npI.@@ ,-@ 000leor pharmaov @ :i::@i@ - @ @iih inoorporaled r@ @i;>@ @@JJ @ — @ @‘@—— -@ @: - - .-‘ @ ‘“ NEW PRODUCTS FROM NPI . Call our Toll Free Customer ServIce Number - 1-800-821-0547 AN PEN AND SHUT CASE! 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AccuSync5R Features •Isolation Amplifier for Patient Safety. •Digital CR1 Monitor. •ECG Strip Chart Recorder. •Heart Rate/R-R mt. •Trigger Pulse LED. •Trigger Control for Ease of Lead Placement and Precise Location of Trigger Pulse. •R-Trigger Output, Compatible with all Computers. •No Delay. •ECG Output •Playback Mode. (optional) •Event Marker. (optional) •Audio Indicator. FEATURES MODEL All AccuSync-5R features