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Nutraceutical, Nutrition Supplements and Human Health Human and Supplements Nutrition Nutraceutical, • Rafat A. and Siddiqui Mohammed H. Moghadasian Nutraceutical, Nutrition Supplements and Human Health Edited by Rafat A. Siddiqui and Mohammed H. Moghadasian Printed Edition of the Special Issue Published in Nutrients www.mdpi.com/journal/nutrients Nutraceutical, Nutrition Supplements and Human Health Nutraceutical, Nutrition Supplements and Human Health Special Issue Editors Rafat A. Siddiqui Mohammed H. Moghadasian MDPI • Basel • Beijing • Wuhan • Barcelona • Belgrade • Manchester • Tokyo • Cluj • Tianjin Special Issue Editors Rafat A. Siddiqui Mohammed H. Moghadasian Virginia State University St. Boniface Hospital USA Canada Editorial Office MDPI St. Alban-Anlage 66 4052 Basel, Switzerland This is a reprint of articles from the Special Issue published online in the open access journal Nutrients (ISSN 2072-6643) (available at: https://www.mdpi.com/journal/nutrients/special issues/ Nutraceutica Nutrition). For citation purposes, cite each article independently as indicated on the article page online and as indicated below: LastName, A.A.; LastName, B.B.; LastName, C.C. Article Title. Journal Name Year, Article Number, Page Range. ISBN 978-3-03936-555-5 (Hbk) ISBN 978-3-03936-556-2 (PDF) c 2020 by the authors. Articles in this book are Open Access and distributed under the Creative Commons Attribution (CC BY) license, which allows users to download, copy and build upon published articles, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. The book as a whole is distributed by MDPI under the terms and conditions of the Creative Commons license CC BY-NC-ND. Contents About the Special Issue Editors ..................................... ix Rafat A. Siddiqui and Mohammed H. Moghadasian Nutraceuticals and Nutrition Supplements: Challenges and Opportunities Reprinted from: Nutrients 2020, 12, 1593, doi:10.3390/nu12061593 .................. 1 Kazuya Toda, Yuki Yamauchi, Azusa Tanaka, Tetsuya Kuhara, Toshitaka Odamaki, Shin Yoshimoto and Jin-zhong Xiao Heat-Killed Bifidobacterium breve B-3 Enhances Muscle Functions: Possible Involvement of Increases in Muscle Mass and Mitochondrial Biogenesis Reprinted from: Nutrients 2020, 12, 219, doi:10.3390/nu12010219 ................... 5 Dina C. Simes, Carla S. B. Viegas, Nuna Araujo ´ and Catarina Marreiros Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases Reprinted from: Nutrients 2020, 12, 138, doi:10.3390/nu12010138 ................... 19 Yair Olovaldo Santiago-Saenz, Rebeca Monroy-Torres, Diana Olivia Rocha-Amador and Alma Delia Hern´andez-Fuentes Effect of a Supplementation with Two Quelites on Urinary Excretion of Arsenic in Adolescents Exposed to Water Contaminated with the Metalloid in a Community in the State of Guanajuato, Mexico Reprinted from: Nutrients 2020, 12, 98, doi:10.3390/nu12010098 ................... 43 Alessandra Durazzo, Emanuela Camilli, Laura D’Addezio, Raffaela Piccinelli, Angelika Mantur-Vierendeel, Luisa Marletta, Paul Finglas, Aida Turrini and Stefania Sette Development of Dietary Supplement Label Database in Italy: Focus of FoodEx2 Coding Reprinted from: Nutrients 2020, 12, 89, doi:10.3390/nu12010089 ................... 65 Se-Chun Liao, Wei-Hsiang Hsu, Zi-Yi Huang, Kun-Lin Chuang, Kuan-Ting Lin, Chia-Ling Tseng, Tung-Hu Tsai, Anh-Hoang Dao, Chun-Li Su and Chi-Ying F. Huang Bioactivity Evaluation of a Novel Formulated Curcumin Reprinted from: Nutrients 2019, 11, 2982, doi:10.3390/nu11122982 .................. 75 Mohammed H. Moghadasian, Ramandeep Kaur, Kayla Kostal, Akhila A. Joshi, Mahboubeh Molaei, Khuong Le, Gabor Fischer, Francesca Bonomini, Gaia Favero, Rita Rezzani and et al. Anti-Atherosclerotic Properties of Wild Rice in Low-Density Lipoprotein Receptor Knockout Mice: The Gut Microbiome, Cytokines, and Metabolomics Study Reprinted from: Nutrients 2019, 11, 2894, doi:10.3390/nu11122894 .................. 97 Ye Jin Kim, Eun-Young Kwon, Ji-Won Kim, Youngmi Lee, Ri Ryu, Jongbok Yun, Manheun Kim and Myung-Sook Choi Intervention Study on the Efficacy and Safety of Platycodon grandiflorus Ethanol Extract in Overweight or Moderately Obese Adults: A Single-Center, Randomized, Double-Blind, Placebo-Controlled Trial Reprinted from: Nutrients 2019, 11, 2445, doi:10.3390/nu11102445 ..................111 v Michael Schmiech, Sophia J. Lang, Judith Ulrich, Katharina Werner, Luay J. Rashan, Tatiana Syrovets and Thomas Simmet Comparative Investigation of Frankincense Nutraceuticals: Correlation of Boswellic and Lupeolic Acid Contents with Cytokine Release Inhibition and Toxicity against Triple-Negative Breast Cancer Cells Reprinted from: Nutrients 2019, 11, 2341, doi:10.3390/nu11102341 ..................123 Melanie S. Trudeau, Robyn F. Madden, Jill A. Parnell, W. Ben Gibbard and Jane Shearer Dietary and Supplement-Based Complementary and Alternative Medicine Use in Pediatric Autism Spectrum Disorder Reprinted from: Nutrients 2019, 11, 1783, doi:10.3390/nu11081783 ..................141 Chyn Boon Wong, Noriyuki Iwabuchi and Jin-zhong Xiao Exploring the Science behind Bifidobacterium breve M-16V in Infant Health Reprinted from: Nutrients 2019, 11, 1724, doi:10.3390/nu11081724 ..................153 Lidiani F. Santana, Aline C. Inada, Bruna Larissa Spontoni do Espirito Santo, Wander F. O. Filiu, ´ Arnildo Pott, Fl´avio M. Alves, Rita de C´assia A. Guimar˜aes, Karine de C´assia Freitas and Priscila A. Hiane Nutraceutical Potential of Carica papaya in Metabolic Syndrome Reprinted from: Nutrients 2019, 11, 1608, doi:10.3390/nu11071608 ..................177 Sandramara Sasso, Priscilla Cristovam Sampaio e Souza, Lidiani Figueiredo Santana, Claudia Andr´ea Lima Cardoso, Fl´avio Macedo Alves, Luciane Candeloro Portugal, Bernardo Bacelar de Faria, Anderson Fernandes da Silva, Ana Rita Coimbra Motta-Castro, Luana Silva Soares and et al. Use of an Extract of Annona muricata Linn to Prevent High-Fat Diet Induced Metabolic Disorders in C57BL/6 Mice Reprinted from: Nutrients 2019, 11, 1509, doi:10.3390/nu11071509 ..................197 Faten A. Alsolmei, Haiwen Li, Suzette L. Pereira, Padmavathy Krishnan, Paul W. Johns and Rafat A. Siddiqui Polyphenol-Enriched Plum Extract Enhances Myotubule Formation and Anabolism while Attenuating Colon Cancer-induced Cellular Damage in C2C12 Cells Reprinted from: Nutrients 2019, 11, 1077, doi:10.3390/nu11051077 ..................219 Virginia Mart´ın, Nivia C´ardenas, Sara Ocana, ˜ Mar´ıa Mar´ın, Rebeca Arroyo, David Beltr´an, Carlos Badiola, Le´onides Fern´andez and Juan M. Rodr´ıguez Rectal and Vaginal Eradication of Streptococcus agalactiae (GBS) in Pregnant Women by Using Lactobacillus salivarius CECT 9145, A Target-specific Probiotic Strain Reprinted from: Nutrients 2019, 11, 810, doi:10.3390/nu11040810 ...................237 Bill J. Gurley, Isabelle R. Miousse, Intawat Nookaew, Laura E. Ewing, Charles M. Skinner, Piroon Jenjaroenpun, Thidathip Wongsurawat, Stefanie Kennon-McGill, Bharathi Avula, Ji-Yeong Bae, Mitchell R. McGill, David Ussery, Ikhlas A. Khan and Igor Koturbash Decaffeinated Green Tea Extract Does Not Elicit Hepatotoxic Effects and Modulates the Gut Microbiome in Lean B6C3F1 Mice Reprinted from: Nutrients 2019, 11, 776, doi:10.3390/nu11040776 ...................259 Amine Allaoui, Sonia Gasc´on, Souhila Benomar, Javier Quero, Jesus ´ Osada, Moncef Nasri, Mar´ıa Jesus ´ Rodr´ıguez-Yoldi and Ahmed Boualga Protein Hydrolysates from Fenugreek (Trigonella foenum graecum) as Nutraceutical Molecules in Colon Cancer Treatment Reprinted from: Nutrients 2019, 11, 724, doi:10.3390/nu11040724 ...................273 vi Alessio Martucci, Delia Reurean-Pintilei and Anamaria Manole Bioavailability and Sustained Plasma Concentrations of CoQ10 in Healthy Volunteers by a Novel Oral Timed-Release Preparation Reprinted from: Nutrients 2019, 11, 527, doi:10.3390/nu11030527 ...................289 Sung Ho Lim and Chang-Ik Choi Pharmacological Properties of Morus nigra L. (Black Mulberry) as A Promising Nutraceutical Resource Reprinted from: Nutrients 2019, 11, 437, doi:10.3390/nu11020437 ...................303 Nivia C´ardenas, Virginia Mart´ın, Rebeca Arroyo, Mario L´opez, Marta Carrera, Carlos Badiola, Esther Jim´enez and Juan M. Rodr´ıguez Prevention of Recurrent Acute Otitis Media in Children Through the Use of Lactobacillus salivarius PS7, a Target-Specific Probiotic Strain Reprinted from: Nutrients 2019, 11, 376, doi:10.3390/nu11020376 ...................321 vii About the Special Issue Editors Rafat A. Siddiqui, Associate Professor. Dr. Rafat Siddiqui is currently working as Associate Professor and Director of the Nutrition Science Food Chemistry Laboratory at Virginia State University, Petersburg, Virginia, United States. Dr. Siddiqui earned his BSc and MSc degrees in Biochemistry from the University of Karachi in Karachi, Pakistan. He obtained his Ph.D. from the Australian National University in Canberra, Australia. Dr. Siddiqui served as a postdoctoral fellow at Massey University in Palmerton North, New Zealand. He immigrated to America in 1989 and worked as a Howard Hughes Research Fellow at Vanderbilt University Medical Center in Nashville. Dr. Siddiqui began his work as a researcher at Methodist Hospital/Methodist Research Institute in 1993 and served as the Director of Cellular Biochemistry and Lipid Biology programs from 2000–2015. He is an internationally recognized expert in nutrition in many areas, including cancer,
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