The Essential Psychedelic Guide (PDF)
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4/23/2015 1 •Psychedelics Or Hallucinogens
4/23/2015 Hallucinogens •Psychedelics or This “classic” hallucinogen column The 2 groups below are quite different produce similar effects From the classic hallucinogens Hallucinogens Drugs Stimulating 5HT Receptors Drugs BLOCKING ACH Receptors • aka “psychotomimetics” LSD Nightshade(Datura) Psilocybin Mushrooms Jimsonweed Morning Glory Seeds Atropine Dimethyltryptamine Scopolamine What do the very mixed group of hallucinogens found around the world share in common? •Drugs Resembling NE Drugs BLOCKING Glutamate Receptors •Peyote cactus Phencyclidine (PCP) •Mescaline Ketamine All contain something that resembles a •Methylated amphetamines like MDMA High dose dextromethorphan •Nutmeg neurotransmitter •New synthetic variations (“bath salts”) •5HT-Like Hallucinogens •LSD History • Serotonin • created by Albert Hofmann for Sandoz Pharmaceuticals LSD • was studying vasoconstriction produced by ergot alkaloids LSD • initial exposure was accidental absorption thru skin • so potent ED is in millionths of a gram (25-250 micrograms) & must be delivered on something else (sugar cube, gelatin square, paper) Psilocybin Activate 5HT2 receptors , especially in prefrontal cortex and limbic areas, but is not readily metabolized •Characteristics of LSD & Other “Typical” •Common Effects Hallucinogens • Sensory distortions (color, size, shape, movement), • Autonomic (mostly sympathetic) changes occur first constantly changing (relatively mild) • Vivid closed eye imagery • Sensory/perceptual changes follow • Synesthesia (crossing of senses – e.g. hearing music -
Hallucinogens - LSD, Peyote, Psilocybin, and PCP
Information for Behavioral Health Providers in Primary Care Hallucinogens - LSD, Peyote, Psilocybin, and PCP What are Hallucinogens? Hallucinogenic compounds found in some plants and mushrooms (or their extracts) have been used— mostly during religious rituals—for centuries. Almost all hallucinogens contain nitrogen and are classified as alkaloids. Many hallucinogens have chemical structures similar to those of natural neurotransmitters (e.g., acetylcholine-, serotonin-, or catecholamine-like). While the exact mechanisms by which hallucinogens exert their effects remain unclear, research suggests that these drugs work, at least partially, by temporarily interfering with neurotransmitter action or by binding to their receptor sites. This InfoFacts will discuss four common types of hallucinogens: LSD (d-lysergic acid diethylamide) is one of the most potent mood-changing chemicals. It was discovered in 1938 and is manufactured from lysergic acid, which is found in ergot, a fungus that grows on rye and other grains. Peyote is a small, spineless cactus in which the principal active ingredient is mescaline. This plant has been used by natives in northern Mexico and the southwestern United States as a part of religious ceremonies. Mescaline can also be produced through chemical synthesis. Psilocybin (4-phosphoryloxy-N, N-dimethyltryptamine) is obtained from certain types of mushrooms that are indigenous to tropical and subtropical regions of South America, Mexico, and the United States. These mushrooms typically contain less than 0.5 percent psilocybin plus trace amounts of psilocin, another hallucinogenic substance. PCP (phencyclidine) was developed in the 1950s as an intravenous anesthetic. Its use has since been discontinued due to serious adverse effects. How Are Hallucinogens Abused? The very same characteristics that led to the incorporation of hallucinogens into ritualistic or spiritual traditions have also led to their propagation as drugs of abuse. -
Psychedelic Resource List.Pdf
A Note from the Author… The Psychedelic Resource List (PRL) was born in 1994 as a subscription-based newsletter. In 1996, everything that had previously been published, along with a bounty of new material, was updated and compiled into a book. From 1996 until 2004, several new editions of the book were produced. With each new version, a decrease in font size correlated to an increase in information. The task of revising the book grew continually larger. Two attempts to create an updated fifth edition both fizzled out. I finally accepted that keeping on top of all of the new books, businesses, and organizations, had become a more formidable challenge than I wished to take on. In any case, these days folks can find much of what they are looking for by simply using an Internet search engine. Even though much of the PRL is now extremely dated, it occurred to me that there are two reasons why making it available on the web might be of value. First, despite the fact that a good deal of the book’s content describes things that are no longer extant, certainly some of the content relates to writings that are still available and businesses or organizations that are still in operation. The opinions expressed regarding such literature and groups may remain helpful for those who are attempting to navigate the field for solid resources, or who need some guidance regarding what’s best to avoid. Second, the book acts as a snapshot of underground culture at a particular point in history. As such, it may be found to be an enjoyable glimpse of the psychedelic scene during the late 1990s and early 2000s. -
Download Book Sacred Journeys As
Sa cred Jour neys: ©2015, 2016, 2017 Artscience Im ages: authors and friends, com pany and press pic- tures, PhotoDisc, Corel, Wikipedia, Mindlift Beeldbankiers. Dis tri bu tion: Boekencoöperatie Nederland u.a. email: [email protected] www.boekcoop.nl www.boekenroute.nl (webshop) All rights re served, in clud ing dig i tal re dis tri bu tion and ebook First editiion: De cem ber 2015, Sec ond, ap pended edition April 2016 Third edition Jan. 2017 ISBN 9789492079091 pub lisher: Onderstroomboven Collectief im print: Artscience. Pa perback price € 6,95 Con tents 1 Pre fa ce 7 2 Tripping: the process 10 Journey to the dream 10 The pre pa ra ti on 11 Pha ses, gig gling 13 Iso la ti on, li mi na li ty, the dark 14 Peak 19 Sit ters: de sig na ted hel pers 22 The mys ti cal, re gres si on 26 Rebirth and de ath 27 The end of the trip: co ming down 28 Over sti mu la ti on 29 The af ter-ef fects 30 3 Set and Set ting 32 Agen da 33 Pla ce 34 With whom, with what? 34 Bon ding and trans fe ren ce 35 Dif fe rent ways of using 36 4 Pur po se 37 Dee per goals 38 Over co ming fear 40 To le ran ce 41 5 Ri tu als and Group ses sions 42 He a ling jour neys, mys ti cal in sights 44 Me di cal use 45 Re pe ti ti on, loops 46 Stages of a ritu al 49 Ri tes of pas sa ge: ini ti a ti on 50 Contact – alignment - group mind 52 Struc tu re amidst cha os 54 To copy an existing ritu al or to crea te somet hing new 54 6 Sanc tu a ry, safe spa ce 57 Sa fe ty first 57 Sa cred spa ce, tem po ra ry au to no mous zone 58 Hol ding spa ce and cir cle in te gri ty 61 7 His to ry -
D. M. Turner - Table of Contents
Sssshhhh!! Don't blow our Cover!! file:///C|/Documents%20and%20Settings/All%20Users/Docume...r%20-%20the%20essential%20psychedelic%20guide/cover.html4/14/2004 9:40:08 PM D. M. Turner - Table of Contents TABLE OF CONTENTS Publication Information Foreword to the HTML Edition - by Forbidden Donut Introduction A Brief History of Psychedelics - From the Creation of Gods to the Demise of Psychedelic Reverence in Modern Times Psychedelic Safety - Understanding the Tools I - Traditional Psychedelics LSD - Molecule of Perfection Psilocybin Mushrooms - The Extraterrestrial Infiltration of Earth? Mescaline: Peyote & San Pedro Cactus - Shamanic Sacraments II - Empathogens Ecstasy - The Heart Opening Psychedelic 2C-B - The Erotic Empathogen III - Exotic Highs of a Connoisseur DMT - Candy for the Mind file:///C|/Documents%20and%20Settings/All%20Users/Doc...%20-%20the%20essential%20psychedelic%20guide/toc.html (1 of 2)4/14/2004 9:40:34 PM D. M. Turner - Table of Contents Harmala Alkaloids - Link to the Ancient Spirits Ketamine - The Ultimate Psychedelic Journey Multiple Combinations - Cosmic Synergism Further Explorations - Where do we go from Here? DMT ~ Water Spirit - A Magical Link Psychedelic Reality - CydelikSpace Bibliography Purchasing The Essential Psychedelic Guide Back Cover Text file:///C|/Documents%20and%20Settings/All%20Users/Doc...%20-%20the%20essential%20psychedelic%20guide/toc.html (2 of 2)4/14/2004 9:40:34 PM D. M. Turner - Publication Information The Essential Psychedelic Guide - By D. M. Turner First Printing - September 1994 Copyright ©1994 by Panther Press ISBN 0-9642636-1-0 Library of Congress Catalog registration in progress Printed in the United States of America Cover art by Nick Philip, SFX Lab Illustrations on pages 31, 41, 45, and 59 by P.B.M. -
Psilocybin Mushrooms Fact Sheet
Psilocybin Mushrooms Fact Sheet January 2017 What are psilocybin, or “magic,” mushrooms? For the next two decades thousands of doses of psilocybin were administered in clinical experiments. Psilocybin is the main ingredient found in several types Psychiatrists, scientists and mental health of psychoactive mushrooms, making it perhaps the professionals considered psychedelics like psilocybin i best-known naturally-occurring psychedelic drug. to be promising treatments as an aid to therapy for a Although psilocybin is considered active at doses broad range of psychiatric diagnoses, including around 3-4 mg, a common dose used in clinical alcoholism, schizophrenia, autism spectrum disorders, ii,iii,iv research settings ranges from 14-30 mg. Its obsessive-compulsive disorder, and depression.xiii effects on the brain are attributed to its active Many more people were also introduced to psilocybin metabolite, psilocin. Psilocybin is most commonly mushrooms and other psychedelics as part of various found in wild or homegrown mushrooms and sold religious or spiritual practices, for mental and either fresh or dried. The most popular species of emotional exploration, or to enhance wellness and psilocybin mushrooms is Psilocybe cubensis, which is creativity.xiv usually taken orally either by eating dried caps and stems or steeped in hot water and drunk as a tea, with Despite this long history and ongoing research into its v a common dose around 1-2.5 grams. therapeutic and medical benefits,xv since 1970 psilocybin and psilocin have been listed in Schedule I of the Controlled Substances Act, the most heavily Scientists and mental health professionals criminalized category for drugs considered to have a consider psychedelics like psilocybin to be “high potential for abuse” and no currently accepted promising treatments as an aid to therapy for a medical use – though when it comes to psilocybin broad range of psychiatric diagnoses. -
Near the Himalayas, from Kashmir to Sikkim, at Altitudes the Catholic Inquisition, and the Traditional Use of These of up to 2700 Meters
Year of edition: 2018 Authors of the text: Marc Aixalà & José Carlos Bouso Edition: Alex Verdaguer | Genís Oña | Kiko Castellanos Illustrations: Alba Teixidor EU Project: New Approaches in Harm Reduction Policies and Practices (NAHRPP) Special thanks to collaborators Alejandro Ponce (in Peyote report) and Eduardo Carchedi (in Kambó report). TECHNICAL REPORT ON PSYCHOACTIVE ETHNOBOTANICALS Volumes I - II - III ICEERS International Center for Ethnobotanical Education Research and Service INDEX SALVIA DIVINORUM 7 AMANITA MUSCARIA 13 DATURA STRAMONIUM 19 KRATOM 23 PEYOTE 29 BUFO ALVARIUS 37 PSILOCYBIN MUSHROOMS 43 IPOMOEA VIOLACEA 51 AYAHUASCA 57 IBOGA 67 KAMBÓ 73 SAN PEDRO 79 6 SALVIA DIVINORUM SALVIA DIVINORUM The effects of the Hierba Pastora have been used by Mazatec Indians since ancient times to treat diseases and for divinatory purposes. The psychoactive compound Salvia divinorum contains, Salvinorin A, is the most potent naturally occurring psychoactive substance known. BASIC INFO Ska Pastora has been used in divination and healing Salvia divinorum is a perennial plant native to the Maza- rituals, similar to psilocybin mushrooms. Maria Sabina tec areas of the Sierra Madre Oriental Mountains of Mexi- told Wasson and Hofmann (the discoverers of its Mazatec co. Its habitat is tropical forests, where it grows between usage) that Salvia divinorum was used in times when the- 300 and 800 meters above sea level. It belongs to the re was a shortage of mushrooms. Some sources that have Lamiaceae family, and is mainly reproduced by cuttings done later feldwork point out that the use of S. divinorum since it rarely produces seeds. may be more widespread than originally believed, even in times when mushrooms were abundant. -
Microgram Journal, Vol 2, Number 1
Washington, D. C. Office of Science and Education Vol.II,No.1 Division of Laboratory Operations January 1969 INDEXISSUE CORRECTION 11 "Structure Elucidation of 'LBJ' , by Sander W. Bellman, John W. Turczan, James Heagy and Ted M. Hopes, Micro Gram .!., 3, 6-13 (Dec. 1968) Page 7, third and fourth sentences under Discussion: Change to read: "The melting point of the acid moiety found in step (g) was 148-150°c., compared to the litera ture, v~lue of 151°c for the melting point of benzilic acid (2); thus the benzilic acid melting point gives support to the proposed structure for 'LBJ'. Spectral evidence also supports the proposed structure". MICRO-GRAMREVISION Please re-number the pages of your copies of Micro-Gram, Volume I. Re-number pages bearing printing only. Vol ume I will then be numbered from page 1, the front page of issue No. 1, through page 189 the last page of issue No. 12. To help with this task, pages contained within each issue are as follows: Issue Number Page Through 1 1 8 2 9 29 3 30 32 4 33 66 5 67 79 6 80 97 7 98 120 8 121 128 9 129 136 10 137 157 11 158 170 12 171 189 CAUTION: Use of this publication should be restricted to forensic analysts or others having a legitimate need for this material. From the Archive Library of Erowid Center http://erowid.org/library/periodicals/microgram -2- CANNABIS ,·,-...__/' Attached is a copy of 11A Short Rapid Method for the Identification of Cannabis." The method was developed by Mro H.D. -
Downloaded from by Pediatricsguest on October Vol.3, 2021 109 No
Just a Click Away: Recreational Drug Web Sites on the Internet Paul M. Wax, MD ABSTRACT. The explosive growth of the Internet in sharp rise in MDMA use among college students as recent years has provided a revolutionary new means of well.3 The report of the Drug Abuse Warning Net- interpersonal communication and connectivity. Informa- work released in December 2000 reveals that emer- tion on recreational drugs—once limited to bookstores, gency department (ED) episodes related to MDMA, libraries, mass media, and personal contacts—is now GHB, and ketamine increased significantly during readily available to just about anyone with Internet ac- 4 cess. Not surprising, Internet access greatly facilitates the the period 1994 to 1999. In addition, abuse of some free and easy exchange of ideas, opinions, and unedited older drugs, such as dextromethorphan, seems to be 5 and nonrefereed information about recreational drugs. on the upsurge. This article presents a patient who came to medical at- Simultaneous with this “club” drug revolution has tention as the result of recreational drug-taking behavior been the explosive growth of the Internet. A dra- directly influenced by her Internet browsing. A second matic change in the everyday means of communica- case is presented in which the only information available tions has taken place. E-mail is now ubiquitous, and about the medical effects of a new “designer” drug was the World Wide Web, known as the Internet, brings found on a recreational drug Internet Web site. Several people together from all over the world attracted by such Web sites are described in detail. -
Motivation of an Entheogenic Chemist
1 (A Brief History and) Motivation of an Entheogenic Chemist Casey William Hardison - POWd (Civ) Abstract Casey Hardison was arrested spring 2004 for the production of psychedelic-type drugs, i.e., LSD, 2C- B and DMT. In the three years since, not one person from ‘authority’ had bothered to ask him what motivated him to synthesise psychedelic drugs. It was as if the a priori assumption that ‘all illegal drugs are bad’ had provided the answer. Hence, the Judge asserted that Hardison did it for “that basest of human emotion, greed” as though the psychospiritual benefits of an alchemical path dedicated to expanding consciousness and personal transformation, through insights integrated into action, upon which he had expounded at great lengths during trial, were some elaborate “portmanteau defence”, just some ruse to get him out of the dock. It was not, it was a committed stand for ‘cognitive liberty’ and for a world full of people who understand the fine line between alone and all one. MINDSET I was born in Washington State on the edge of Western exploration in the New World in the summer of 1971. I came of age in and around the communal rooms of AA, NA, ACA, Alanon and Alateen throughout the Pacific and Mountain West. My father is 33 years sober. His father died 14 years sober in 1982. I too wrestled my psychospiritual demons through alcohol and Cannabis which gratefully led me to the rooms of AA and NA where, at the age of 14, I declared myself an alcoholic and an addict. I delved headlong into the 12 Steps and promptly saw that I had wrapped myself in a shame-bound identity (‘ism’ - internalised shame manifested). -
Asymmetric Synthesis of Α-N,N-Dialkylamino Alcohols by Transfer Hydrogenation of N,N-Dialkylamino Ketones
Acta Poloniae Pharmaceutica ñ Drug Research, Vol. 67 No. 6 pp. 717ñ721, 2010 ISSN 0001-6837 Polish Pharmaceutical Society ASYMMETRIC SYNTHESIS OF α-N,N-DIALKYLAMINO ALCOHOLS BY TRANSFER HYDROGENATION OF N,N-DIALKYLAMINO KETONES TOMASZ KOSMALSKI Department of Organic Chemistry, Collegium Medicum, Nicolaus Copernicus University, M. Curie-Sk≥odowska 9, 85-067, Bydgoszcz, Poland Keywords: β-amino alcohols, Noyori`s catalyst, asymmetric transfer hydrogenation (ATH) β-Amino alcohols are important physiological- instrument. MS spectra were recorded on an AMD ly active compounds (1, 2a,b), also used as ligands 604 spectrometer. Optical rotations were measured (3, 4), and precursors of oxazaborolidines (5). on an Optical Activity PolAAr 3000 automatic Various methods for their asymmetric synthesis, polarimeter. GC analyses were performed on a such as the reduction of α-functionalized ketones Perkin-Elmer Auto System XL chromatograph, with hydrides (6, 7), catalytic hydrogenation of HPLC analyses were performed on a Shimadzu LC- amino ketones (8), reduction with borane/oxaza- 10 AT chromatograph. Melting points were deter- borolidines (9, 10), and other approaches (11ñ13) mined in open glass capillaries and are uncorrected. have been developed. However, the existing meth- Elemental analyses were performed by the ods are not ideal. For example, chiral β-chloro Microanalysis Laboratory, Institute of Organic hydrins, obtained by the reduction of α-chloro Chemistry, Polish Academy of Sciences, Warszawa. ketones, can be transformed into β-amino alcohols Silica gel 60, Merck 230ñ400 mesh was used for by treatment with secondary amines, however, mix- preparative column chromatography. Macherey- tures of isomers are sometimes formed (14). Nagel Polygram Sil G/UV254 0.2 nm plates were Asymmetric transfer hydrogenation (15, 16) used for analytical TLC. -
The Experience Elicited by Hallucinogens Presents the Highest Similarity to Dreaming Within a Large Database of Psychoactive Substance Reports
ORIGINAL RESEARCH published: 22 January 2018 doi: 10.3389/fnins.2018.00007 The Experience Elicited by Hallucinogens Presents the Highest Similarity to Dreaming within a Large Database of Psychoactive Substance Reports Camila Sanz 1, Federico Zamberlan 1, Earth Erowid 2, Fire Erowid 2 and Enzo Tagliazucchi 1,3* 1 Departamento de Física, Universidad de Buenos Aires, Buenos Aires, Argentina, 2 Erowid Center, Grass Valley, CA, United States, 3 Brain and Spine Institute, Paris, France Ever since the modern rediscovery of psychedelic substances by Western society, Edited by: several authors have independently proposed that their effects bear a high resemblance Rick Strassman, to the dreams and dreamlike experiences occurring naturally during the sleep-wake University of New Mexico School of cycle. Recent studies in humans have provided neurophysiological evidence supporting Medicine, United States this hypothesis. However, a rigorous comparative analysis of the phenomenology (“what Reviewed by: Matthias E. Liechti, it feels like” to experience these states) is currently lacking. We investigated the semantic University Hospital Basel, Switzerland similarity between a large number of subjective reports of psychoactive substances and Michael Kometer, University of Zurich, Switzerland reports of high/low lucidity dreams, and found that the highest-ranking substance in *Correspondence: terms of the similarity to high lucidity dreams was the serotonergic psychedelic lysergic Enzo Tagliazucchi acid diethylamide (LSD), whereas the highest-ranking in terms of the similarity to dreams [email protected] of low lucidity were plants of the Datura genus, rich in deliriant tropane alkaloids. Specialty section: Conversely, sedatives, stimulants, antipsychotics, and antidepressants comprised most This article was submitted to of the lowest-ranking substances.