Reflections, Frank Fenner

Total Page:16

File Type:pdf, Size:1020Kb

Reflections, Frank Fenner 327 Chapter 18. Reflections, Frank Fenner In this final chapter, I want to reflect on two matters, one that spanned my working life, namely special friendships, and the other an analysis of the relative importance of nature, nurture and chance, as they affected my father and myself. Special Friends Friendships are an important element in everyone©s life. Lifelong friendship with one©s wife is the most important and one that I enjoyed in full measure, but I have had many other friends. Here I want to acknowledge the debt I owe to several special friends who have been important to me at various periods of my life, many of who still are. I mention a number of them at some length in the ©boxes© in earlier chapters; those who were close personal friends were Ted Ford, Cecil Hackett, Francis Ratcliffe, Ian Marshall, Gwen Woodroofe, D. A. Henderson and Isao Arita. Two of my mentors, Macfarlane Burnet and René Dubos, were also close friends. Here I will list some other friends chronologically and alphabetically and provide a few comments on each of them. School Days The one person who I remember as a special friend from primary school days is John Dowie, a noted sculptor and painter who still lives in the same house as he did in the 1920s. I greatly enjoyed visiting him in his house and studio, with my sister Winn and my brother Bill, as recently as April 2005. The one person I remember from Thebarton Technical High School is Alf Chittoch, who I met again when I visited Tennant Creek in 1968, where he has lived since the war and risen from being a `battler' in the mines to Mayor. We have maintained annual correspondence ever since. University Days The friend that I remember best from Adelaide High School and university days is Denis Shortridge, who subsequently became an ophthalmologist in Sydney. Later he moved back to Adelaide and I used to visit him every time I went there until he died in the mid-1990s. In recent years, whenever I visit Adelaide I arrange to have lunch at the Army and Navy Club with all those of my year at medical school who are able to come. We had a special meal there in 1994 to which about a dozen came; now the `regulars' have fallen to two, Alan Campbell and Malcolm Newland. Army Days My best friend in early Army days was Noel Bonnin, a surgeon who was six years older than me but who was initially in the same unit as I was (2/6 Field 328 Nature, Nurture and Chance Ambulance) and carried out some research with me when we were in the Woodside Camp. Later, when we were both in the same unit in Lebanon (2/1 Casualty Clearing Station) we went on two wonderful week-long trips, first to Petra and then to Luxor and Aswan. Later my close friends in the 2/2 Australian General Hospital were Orme Smith, Ian Wood and Rod Andrew, and in New Guinea, Ted Ford. Melbourne Days I lived in Melbourne from October 1945 to August 1948, and again from February 1950 to November 1952. During the second period, Bobbie and I lived in and she looked after the houses and children of Alan and Mavis Jackson (I knew Alan in New Guinea as a pathologist and we co-authored one scientific paper) and Macfarlane and Linda Burnet. Both Bobbie and I became close friends of the Burnets and the Jacksons. Canberra Days Bobbie was a much more sociable person than I was, and several of my current friends in Canberra derive from her friendships. In the ANU and especially in the JCSMR, I met a very large number of people, many of whom became close friends. I also met a number of scientists during my overseas travels who became, and remain, close friends. Co-authorship of books was important in developing friendships. I will list some of them as Local Friends and Overseas Friends, arranged alphabetically. Local Friends Gordon Ada I knew Gordon from early Hall Institute days and he came to Canberra several times to give seminars here. In 1962, I tried to recruit him as Reader in Biochemical Microbiology, but the Hall Institute was still too attractive. Then, in 1968, he was appointed as my successor. I moved to CRES in 1973 and we became really close friends in 1991, when he came back to the School as a Visiting Fellow and occupied the office next to mine. Since then we have always had morning coffee together and discuss the woes of the modern world. Rod Andrew Rod was a senior physician in the 2/2 Australian General Hospital when I was there in 1942 and after I went to New Guinea he was deeply involved in looking after volunteers who had been given malaria at the LHQ Medical Research Unit. After the war he became Dean of the Monash Medical School, and in 1964 he was responsible for recommending the award of my first honorary degree (MD). I visited Monash University intermittently after that and, in April 2004, I gave the first Roderick Andrew Oration there. Chapter 18. Reflections, Frank Fenner 329 Stephen Boyden Stephen, an Englishman, worked with René Dubos a year after I did, and was subsequently appointed to the Department of Experimental Pathology in JCSMR. He was elected a Fellow of the Australian Academy of Science in 1966 for his work in immunology, but in 1965 he had decided that he wanted to get away from reductionist science and transferred to my department in that year, to work on human ecology. He subsequently transferred to the new Department of Human Biology and in 1975 to CRES, where he worked until retirement in 1990. In 1991, following the interest expressed by several people in the audience when he gave a lecture at Questacon, he set up a non-governmental community body, the Nature and Society Forum, of which I became an early member and later a patron. I regard him as perhaps the most creative younger scientist whom I have known well (thus excluding Burnet), and he and his wife Rosemary have been among my closest friends, especially during the last decade. Ruth Conley Ruth was the nursing sister at Canberra Boys© Grammar School and a good friend of Bobbie©s. Since Bobbie©s death and her retirement to a cottage near the Yarralumla shops she kindly invites me to have lunch or dinner with her and other friends. Jack Crawford Jack was a senior public servant and a member of the tennis group that I had joined as soon as I was settled in Canberra. In 1960 he was appointed to the ANU as Director of the Research School of Pacific Studies, and from 1968 to 1973, a period coinciding with my term as Director of JCSMR, he was Vice-Chancellor. From the mid-1960s, we were very close friends, and he and his wife Jess played bridge with Bobbie and me every Saturday night for over a decade; we visited Jess every weekend after Jack died in 1984. Walter Crocker Coming from a South Australian farming family, Walter had extensive experience in the British diplomatic corps in Africa during the war. In 1948, Copland persuaded him to join the Research School of Pacific Studies as Professor of International Relations. We got to know him well because he built a house almost opposite ours in Torres Street, Red Hill. He transferred to the Australian diplomatic corps in 1952 and initially filled important posts in India and Indonesia. In 1956, he invited me and two colleagues to Indonesia for three weeks to advise him on the best location for a medical school in Sumatra. Then, in 1960±61, he organized a six-weeks visit for me to virology laboratories all over India. After he retired in 1970, he went back to his farm, but in 1973 he was appointed Lieutenant-Governor of South Australia; I stayed with him once 330 Nature, Nurture and Chance at a time when he was living in Government House. Eventually he retired to a house very near the beach at Grange, an Adelaide suburb on the coast. For many years I used to visit him there whenever I went to Adelaide; he always plied me with penetrating questions. He died in 2002 at the age of 100. David Curtis David had joined Jack Eccles as his first PhD student in 1954. He rose to be Professor of Pharmacology when that department was created in 1973 and was appointed Director of the JCSMR, 1989±92. He was elected a Fellow of the Academy of Science in 1965 and appointed President, 1986±90. He and his wife Laurie were always good friends and he hosted many lovely dinners which we enjoyed at his home in Campbell. In 1999±2001, we collaborated in producing a history of the first 50 years of the John Curtin School. Max Day Max Day was born on exactly the same day as I was, one year later. For many years, Max and his wife Barbara and Bobbie and I would celebrate our birthdays with dinners, alternately at our respective homes. In the early 1950s, he worked in CSIRO Entomology on the transmission of plant viruses and he was the first person with whom I collaborated in laboratory work in Canberra. I used to come up from Melbourne to work with him on the mechanical transmission of myxoma virus by mosquitoes. Later he became a member of the CSIRO Executive and then Chief of the CSIRO Division of Forestry.
Recommended publications
  • The Life and Death of Smallpox Ian and Jenifer Glynn Frontmatter More Information
    Cambridge University Press 0521845424 - The Life and Death of Smallpox Ian and Jenifer Glynn Frontmatter More information The Life and Death of Smallpox This is an engaging and fascinating story of a conditional human success story. Smallpox has been one of the most devastating scourges of humanity throughout recorded history, and it is the only human illness to have been eradicated, though polio may soon follow it to official extinction through human agency. However, while smallpox is officially extinct in nature, our fears that stocks of smallpox virus may return as a weapon of bioterrorists have led to the stockpiling of vaccine, and continuing vigilance, even though the official victory over smallpox is now 15 years old. The Life and Death of Smallpox presents the entire engaging history of our struggle and ultimate (?) victory over one of our oldest and worst enemies. The story of the campaign to track down and eradicate the virus, throughout the world – the difficulties, setbacks, and the challenges successfully met – is a highlight of a fascinating book, but we cannot be confident of the ending. The final chapter of the book clearly and authoritatively explains the current status of the threat from the deliberate release of smallpox or other potential agents of biological terrorism. Ian Glynn is Professor Emeritus of Physiology at Cambridge University and Fellow of Trinity College. He is the author of An Anatomy of Thought (1999). Jenifer Glynn is a Cambridge historian and author of Tidings From Zion (2000). © Cambridge University Press www.cambridge.org Cambridge University Press 0521845424 - The Life and Death of Smallpox Ian and Jenifer Glynn Frontmatter More information The Life and Death of Smallpox IAN AND JENIFER GLYNN © Cambridge University Press www.cambridge.org Cambridge University Press 0521845424 - The Life and Death of Smallpox Ian and Jenifer Glynn Frontmatter More information PUBLISHED BY CAMBRIDGE UNIVERSITY PRESS 40 We s t 20th Street, New York, NY 10011-4211, USA http://www.cambridge.org c Ian and Jenifer Glynn 2004 This book is in copyright.
    [Show full text]
  • The Peace Corps' Contributions to the Global Smallpox Eradication Program
    The Peace Corps’ Contributions to the Global Smallpox Eradication Program About the Office of Strategic Information, Research, and Planning (OSIRP) It is the mission of OSIRP to advance evidence-based management at the Peace Corps by guiding agency strategic planning; monitoring and evaluating agency-level performance and programs; conducting research to generate new insights in the fields of international development, cultural exchange, and Volunteer service; enhancing the stewardship and governance of agency data; and helping to shape agency engagement on high-level, governmentwide initiatives. Front Cover: Peace Corps Volunteers Robert Steinglass and Doug Arbuckle administering the smallpox vaccine in Mille, Ethiopia, in 1974. Photo: Steinglass, personal collection. ii Dedication This report is dedicated to the memory of Dr. Donald Ainslie “D. A.” Henderson (September 7, 1928—August 19, 2016), a seminal figure in the field of smallpox eradication. The Peace Corps is deeply appreciative of having had the opportunity to correspond with Dr. Henderson about the contributions of Peace Corps Volunteers and returned Volunteers within the context of the global eradication program. His charismatic leadership, tireless energy, and unflagging devotion to this program inspired countless public health workers around the world, including many of the returned Peace Corps Volunteers interviewed for this report. iii Acknowledgments In 1806, approximately 10 years after Dr. Edward Jenner conducted the first documented experiment with smallpox vaccination, laying the foundations of modern medicine, President Thomas Jefferson wrote to the English physician and scientist. Jefferson acknowledged the importance of this discovery, extending “a portion of the tribute of gratitude due to you from the whole human family.
    [Show full text]
  • Worldwide Smallpox Eradication, 1957–67
    Med. Hist. (2020), vol. 64(1), pp. 71–93. c The Authors 2019. Published by Cambridge University Press 2019 This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. doi:10.1017/mdh.2019.77 Re-assessing the Foundations: Worldwide Smallpox Eradication, 1957–67 SANJOY BHATTACHARYA 1* and CARLOS EDUARDO D’AVILA PEREIRA CAMPANI 2 1Centre for Global Health Histories, Department of History, University of York, York YO10 5DD, UK 2Department of Health Sciences, University of York, York YO10 5DD, UK Abstract: An expansive, worldwide smallpox eradication programme (SEP) was announced by the World Health Assembly in 1958, leading this decision-making body to instruct the World Health Organization Headquarters in Geneva to work with WHO regional offices to engage and draw in national governments to ensure success. Tabled by the Soviet Union’s representative and passed by a majority vote by member states, the announcement was subject to intense diplomatic negotiations. This led to the formation, expansion and reshaping of an ambitious and complex campaign that cut across continents and countries. This article examines these inter-twining international, regional and national processes, and challenges long-standing historiographical assumptions about the fight against smallpox only gathering strength from the mid-1960s onwards, after the start of a US-supported programme in western Africa. The evidence presented here suggests a far more complex picture. It shows that although the SEP’s structures grew slowly between 1958 and 1967, a worldwide eradication programme resulted from international negotiations made possible through gains during this period.
    [Show full text]
  • The Smallpox Threat: a Time to Reconsider Global Policy
    Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science Volume 12, Number 3, 2014 ª Mary Ann Liebert, Inc. DOI: 10.1089/bsp.2014.1509.comm Commentary The Smallpox Threat: A Time to Reconsider Global Policy D. A. Henderson and Isao Arita n May of this year, the 67th World Health Assembly more than 8 to 10 countries have sufficient vaccine to Iwill again debate the question of when the remaining cope with an outbreak. A WHO global emergency reserve, specimens of smallpox virus should be destroyed. Over the recommended 10 years ago, is steadily shrinking. Strategic past 18 years, this has been on the agenda of 5 previous plans for outbreak containment have been little discussed. Assemblies, the last being in 2011. At that time, the dele- At the same time, 2 initiatives have received special at- gates ‘‘affirmed strongly the decisions of previous Health tention and resources: one to develop a vaccine that would Assemblies that the remaining stocks of variola virus should protect without adverse reactions, and one to perfect an- be destroyed.’’1 They asked that the date be decided by the tiviral drugs to treat cases should they occur. Both have 2014 Assembly. failed to meet expectations. Inordinate amounts of time, effort, and resources have In writing this commentary, we have jointly drawn on been spent in endeavoring to reach consensus on this one our own half-century of experience with smallpox to offer a component of a smallpox threat strategy: whether to de- brief historic context for a better comprehension of current stroy or not destroy smallpox virus strains now being efforts and to critique the contemporary status of pre- retained in the 2 World Health Organization (WHO) paredness and response in coping with the unlikely return Collaborating Laboratories (in the United States and of smallpox, which has played such a dominant role Russia).
    [Show full text]
  • Nature, Nurture and Chance: the Lives of Frank and Charles Fenner
    81 Chapter 6. Professor of Microbiology, John Curtin School of Medical Research, 1949 to 1967: Research Research in Melbourne, February 1950 to November 1952 As mentioned in the previous chapter, The Australian National University had arranged with the Director of the Walter and Eliza Hall Institute, Sir Macfarlane Burnet, to provide me with two laboratories, on the same floor as his laboratory, for as long as it took to provide laboratories in Canberra. I worked in the room previously occupied by gifted research worker Dora Lush, who had died in 1943 from scrub typhus contracted during her work (Burnet, 1971). Molecular biology was unknown in the early 1950s, and although I wanted to get back to virology, I thought that I had skimmed the cream from the study of ectromelia virus. Subsequently it was used by several groups in the John Curtin School as their model virus disease and they continue to use it in studies of molecular virology. At first, Burnet suggested that I might like to take over the field that he had been working on, the genetics of influenza virus. However, I did not want the work of my new department to be too closely associated with someone as distinguished as Burnet, so I did not take up his offer. Studies on Mycobacterium tuberculosis and Mycobacterium ulcerans Initially, I carried on working with Mycobacterium tuberculosis, the major work being a long review article on the vaccine strain, BCG (Fenner, 1951). With a research assistant, Ronald Leach, I also continued laboratory studies of tubercle bacilli and began serious studies of the `Bairnsdale bacillus'.
    [Show full text]
  • WHO Advisory Committee on Variola Virus Research
    WHO/HSE/GAR/BDP/2009.3 WHO Advisory Committee on Variola Virus Research Report of the Eleventh Meeting Geneva, Switzerland 4–5 November 2009 GLOBAL ALERT AND RESPONSE © World Health Organization 2009 All rights reserved. The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distin- guished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication. However, the published material is being distributed without warranty of any kind, either express or implied. The responsibility for the interpretation and use of the material lies with the reader. In no event shall theWorld Health Organization be liable for damages arising from its use. This publication contains the collective views of an international group of experts and does not necessarily represent the decisions or the policies of the World Health Organization. Printed by the WHO Document Production Services, Geneva, Switzerland WHO Advisory Committee on Variola Virus Research Report of the Eleventh Meeting, Geneva, Switzerland, 4–5 November 2009 Executive summary The major accomplishments in the WHO variola virus programme were as follows: WHO smallpox vaccine e mergency stockpile of 32.6 m illion doses was established, well in excess of the original target of five million.
    [Show full text]
  • Seventh Meeting of the WHO/SEAR EPI Technical Consultative Group on Polio Eradication and Vaccine- Preventable Diseases
    SEA-Polio-22 Distribution: General Seventh Meeting of the WHO/SEAR EPI Technical Consultative Group on Polio Eradication and Vaccine- Preventable Diseases Conclusions and Recommendations Calcutta, India, 24 - 26 August 2000 WHO Project: ICP VAB 200 World Health Organization Regional Office for South-East Asia New Delhi November 2000 © Word Health Organization (2000) This document is not a formal publication of the World Health Organization (WHO), and all rights are reserved by the Organization. The document may, however, by freely reviewed, abstracted, reproduced or translated, in part or in whole, but not for sale or for use in conjunction with commercial purposes. The views expressed in documents by named authors are solely the responsibility of those authors. CONTENTS Page 1. INTRODUCTION...........................................................................................1 2. GENERAL SUMMARY.....................................................................................1 3. POLIOMYELITIS ERADICATION .....................................................................2 3.1 Surveillance for Detection of Wild Polioviruses........................................5 3.2 Supplementary Immunization.................................................................7 4. ENSURING VACCINE SUPPLY AND QUALITY ..............................................11 5. ROUTINE IMMUNIZATION .........................................................................12 6. WILD POLIOVIRUS LABORATORY CONTAINMENT.....................................13 7.
    [Show full text]
  • Your Magazine from the British Ecological Society
    The BulletinYOUR MAGAZINE FROM THE BRITISH ECOLOGICAL SOCIETY BES BULLETIN VOLin 44:4FOCUS / DECEMBER 2013 Photo: Danielle Green Danielle’s photo of Mark Browne apparently ‘taking a closer look’ at the mud of County Donegal appealed to the judging panel for the BES photocompetition. There are more images from the competition on p37 onwards. 2 Contents December 2014 OFFICERS AND COUNCIL FOR THE YEAR 2012-3 REGULARS President: Bill Sutherland Welcome / Alan Crowden 4 Past-President: Georgina Mace Vice-Presidents: Richard Bardgett, President’s Piece / W. J. Sutherland 5 Mick Crawley Honorary Treasurer: Drew Purves Ecology Education and Careers / Karen Devine and Christina Ravinet 25 Council Secretary: Dave Hodgson Honorary Chairpersons: Science Policy Andrew Beckerman (Meetings) Holyrood Batman! – The BES’s day in the Scottish Parliament / Rob Brooker 24 Alan Gray (Publications) Lesley Batty (Education, Training Society News 34 and Careers) Juliet Vickery (Public and Policy) Special Interest Group News 41 Richard Bardgett (Grants) ORDINARY MEMBERS Letters to the Editor 50 OF COUNCIL: Retiring Of Interest to Members 51 Emma Goldberg, 2014 William Gosling, Ruth Mitchell The Chartered Institute of Ecology and Environmental Management / Sally Hayns 72 Julia Blanchard, 2015 Greg Hurst, Paul Raven Publishing News: BES Publications Data Archiving Policy / Liz Baker 74 Emma Sayer, Owen Lewis, 2016 Matt O’Callaghan Book Reviews 81 Diana Gilbert, Jane Hill, 2017 Diary 92 Joanna Randall Bulletin Editor: Alan Crowden 48 Thornton Close, Girton, FEATURES
    [Show full text]
  • The Poliovirus Was Belatedly Produced When the Child Found Itself Unprotected by the Immunity Provided by Breast Feeding
    HYGIEA INTERNATIONALIS An Interdisciplinary Journal for the History of Public Health Volume 11, No. 1, 2015 ISSN, Print: 1403-8668; Electronic: 1404-4013 URL: http://www.ep.liu.se/ej/hygiea/ Editorial Board Giovanni Berlinguer, University of Rome “La Sapienza”, Italy Virginia Berridge, London School of Hygiene and Tropical Medicine, U.K. Patrice Bourdelais, École des Hautes Études en Sciences Sociales, France Linda Bryder, University of Auckland, New Zealand Marcos Cueto, Instituto de Estudios Peruanos, Peru Christopher Hamlin, University of Notre Dame, U.S.A. Robert Jütte, Robert Bosch Stiftung, Germany Øivind Larsen, University of Oslo, Norway Marie C. Nelson, Linköping University, Sweden Dorothy E. Porter, University of California, U.S.A. Günter B. Risse, University of California, U.S.A. Esteban Rodriguez-Ocaña, University of Granada, Spain John Rogers, Uppsala University, Sweden Jan Sundin, Linköping University, Sweden Lars-Göran Tedebrand, Umeå University, Sweden John H. Woodward, The University of Sheffield, U.K. Editorial Committee Laurinda Abreu, Patrice Bourdelais, Jan Sundin and Sam Willner Copyright This journal is published under the auspices of Linköping University Electronic Press. All Authors retain the copyright of their articles. © The Authors Table of Contents Volume 11, No. 1, 2015 Sam Willner Foreword 5 Juan Antonio Rodriguez Introduction (Guest Editor) 7 Adrian Carbonetti, Poliomyelitis in the city of Córdoba: Lila Aizenberg Morbidity, knowledge and the research Marina Laura Rodriguez performed by a medical elite
    [Show full text]
  • Nature, Nurture and Chance: the Lives of Frank
    Nature, Nurture and Chance THE LIVES OF FRANK AND CHARLES FENNER Nature, Nurture and Chance THE LIVES OF FRANK AND CHARLES FENNER FRANK FENNER VISITING FELLOW, JOHN CURTIN SCHOOL OF MEDICAL RESEARCH THE AUSTRALIAN NATIONAL UNIVERSITY Published by ANU E Press The Australian National University Canberra ACT 0200, Australia Email: [email protected] Web: http://epress.anu.edu.au National Library of Australia Cataloguing-in-Publication entry Fenner, Frank, 1914- . Nature, nurture and chance : the lives of Frank and Charles Fenner. ISBN 1 920942 62 9 ISBN 1 920942 63 7 (online) 1. Fenner, Frank, 1914- . 2. Fenner, Charles, 1884-1955. 3. Microbiologists - Australia - Biography. 4. Virologists - Australia - Biography. 5. Geographers - Australia - Biography. 6. Educators - Australia - Biography. I. Title. 579.092 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical, photocopying or otherwise, without the prior permission of the publisher. Indexed by Frank Fenner. Cover design by Teresa Prowse. Frank Fenner, by Mathew Lynn, 1999, courtesy of the John Curtin School of Medical Research. Charles Fenner, by Ivor Hele, 1935, courtesy of Education Centre, Adelaide. This edition © 2006 ANU E Press iii Table of Contents List of Figures v Preface vii Acknowledgements xiii Acronyms xv Part I. The Life of Frank Fenner Introduction 3 Chapter 1. Childhood, 1914 to 1932 9 Chapter 2. The University Years, 1933 to 1940 21 Chapter 3. The War Years, May 1940 to February 1946 27 Chapter 4. Walter and Eliza Hall Institute, 1946 to 1948; Rockefeller Institute, 1948 to 1949 47 Chapter 5.
    [Show full text]
  • Eradication of Infectious Diseases: Its Concept, Then And
    Jpn. J. Infect. Dis., 57, 1-6, 2004 Review Eradication of Infectious Diseases: Its Concept, Then and Now Isao Arita*, John Wickett1 and Miyuki Nakane Agency for Cooperation in International Health, Kumamoto 862-0901, Japan and 1World Health Organization, Geneva, Switzerland (Received December 18, 2003. Accepted January 19, 2004) CONTENTS: 1. Background 5. Discussion 2. Building up the concept of eradication based 5-1. Smallpox on the eradication of smallpox 5-2. Polio 3. Application of smallpox experience to polio 5-3. Measles eradication 5-4. Changing world 4. Application to measles eradication of experience 6. Reconsideration of the concept of eradication gained from the smallpox and polio eradication 7. Conclusion programs SUMMARY: The concept of disease eradication emerged as recently as the mid-20th century. The successful eradication of smallpox resulted in the concept of the extinction of the causative agent in man as well as in the environment, leading to the cessation of all control measures including vaccination. Subsequently, world resources have been invested in global polio eradication and measles eradication in the Western Hemisphere. The former is apparently now at the “end game”, the latter, after successful campaign in the Americas, aims at program development worldwide. However, both endeavors are being challenged by delays in schedules, unexpected technical problems, lack of global coordination, and ever-increasing political unrest. It is proposed that disease eradication be redefined as the extinction of the pathogen in man, not in nature, making for a more flexible approach in the post-eradication period. Smallpox eradication was a rare event. That concept is unrealistic in today’s world.
    [Show full text]
  • Smallpox Eradication and Human Morality in Evolution Isao Arita* National Hospital Organization, Kumamoto Medical Center, Japan
    ccines & a V f V a o c l c a i n Arita, J Vaccines Vaccin 2013, 4:4 n a r t u i o o n J Journal of Vaccines & Vaccination DOI: 10.4172/2157-7560.1000188 ISSN: 2157-7560 Review Article Open Access Smallpox Eradication and Human Morality in Evolution Isao Arita* National Hospital Organization, Kumamoto Medical Center, Japan Abstract Successful WHO smallpox eradication is considered to be the unprecedented event in history of human evolution, namely human species’ long struggle with vicious pathogen termed variola or smallpox. The victory resulted from human efforts, firstly recent scientific discovery of vaccine and epidemiological strategy to interrupt the smallpox transmission and secondly the human species’ joint effort to eradicate smallpox despite difference in nationality, race, religions and politics worldwide. In this article, specifically the second elements are discussed in view of Charles Darwin’s struggle for existence and natural selection and his few followers’ opinions that human genome may have an important role in evolution process, for instance, of ethics, morality, as expressed in” Nature via Nurture”: Genes, experience, what makes human. Since the time unmemorable human species suffered considerable tragedy of smallpox disaster, themselves as well as their family and friends without knowing how to escape: Perhaps their ancestors sad memories could have influenced the minds of the staff or villagers, how to contribute themselves for rescuing their fellow human species: Please read and think for the future of human species. Keywords: Smallpox; Human species; Vaccines; Environmental include the social (nature versus nurture) elements that evolved from stress people’s experience dealing with smallpox disasters that occurred since prehistoric time.
    [Show full text]