Annual Report 2007–2008 Annual Report 2007–2008 Jules Stein Eye Institute Jules Stein Eye Institute David Geffen School of Medicine at UCLA University of California, Los Angeles Jules Stein Eye Institute 2007 – 2008 Annual Report 2007–2008 Jules Stein Eye Institute David Geffen School of Medicine at UCLA University of California, Los Angeles ii FacultyAppendices | Endowed Professorships, Fellowships, and Other Funds Jules Stein Eye Institute Annual Report 2007–2008 DIRECTOR Bartly J. Mondino, MD FACULTY ADVISOR Debora B. Farber, PhD, DPhhc MANAGING EDITOR Gloria P. Jurisic EDITORS Irene Y. Chen Tina-Marie Gauthier PHOTOGRAPHY J. Charles Martin DESIGN This report covers the period July 1, 2007, through June 30, 2008. Ikkanda Design Group Requests for additional copies of the publication Jules Stein Eye Institute PRINTING Annual Report 2007–2008 Marina Graphic Center may be sent to: ©2008, by the Regents of the University of California. Office of the Managing Editor All rights reserved. Jules Stein Eye Institute 100 Stein Plaza, UCLA Box 957000 Los Angeles, California 90095–7000 Printed on recycled paper using soy base inks Phone: (310) 206-7178 For more information on the Institute, see our website: www.jsei.org The emblem of the Jules Stein Eye Institute is adapted from the schematic eye used by Sir Isaac Newton in his classic treatise on human vision—“Opticks”—published in 1704. The horizontal lines extending from the surface of the eye represent Newton’s concept of the major colors that are in the spectrum of light. Appendices | Endowed Professorships, Fellowships, and Other Funds iii Contents JULES STEIN v DORIS STEIN v BOARD OF TRUSTEES vi EXECUTIVE COMMITTEE vii FACILITIES viii HIGHLIGHTS 1 Honors 3 Research 6 Education 7 Philanthropy 10 Thank You 12 Community Outreach 13 FACULTY 15 PROGRAMS 63 Patient Care Services 64 Research and Treatment Centers 65 Clinical Laboratories 72 Training Programs 74 APPENDICES 81 Volunteer and Consulting Faculty 82 Residents and Fellows 84 Endowed Professorships, Fellowships, and Other Funds 86 Educational Offerings 90 Research Contracts and Grants 93 Clinical Research Studies 106 Publications of the Full-Time Faculty 111 Giving Opportunities 124 iv Faculty The legacy of Dr. and Mrs. Jules Stein arises from their role in the 20th century as visionaries. Through brilliance and beneficence, they created a multitude of programs aimed specifically at one goal—preserving and restoring eyesight. They approached this task dauntlessly, integrating the worlds of business, medicine, and philanthropy in such a way as to enhance each and leave in trust the promise of limitless accomplishment in the advancement of eye research and treatment. The Jules Stein Eye Institute was established as a result of their philanthropy. Jules and Doris Stein v Jules Stein Institute was founded as a multidisciplinary center for vision science. Since its establishment, the Institute has become internationally identified as the focus for coordinated programs of research in the sciences related to vision, Jules Stein is the foremost benefactor ophthalmic education, and the care of patients with eye in the world history of vision science disease. Jules Stein died in 1981, leaving a legacy of hope to and blindness prevention. He the world. Through his accomplishments and philanthropy, combined his love for music and he created ever replenishing resources for eye research and medicine with a unique talent for the means to preserve and restore sight for future generations. analysis and organization to produce a lifetime of celebrated achievements as musician, physician, business leader, and humanitarian. Doris Stein Born in South Bend, Indiana, in 1896, Jules Stein received a PhB from the University of Chicago at age 18 followed by Doris Stein’s purposeful, yet richly a MD degree from Rush Medical College. After completing varied life earned the respect and postgraduate studies at the University of Vienna and Chicago’s affection of the many people who Cook County Hospital, he began medical practice and was benefited from her humanitarianism. certified by the American Board of Ophthalmology. Inspiring partner of her husband for more than half a century, Doris Stein A musician from an early age, he financed his education by shared with him the accomplishments of his philanthropic playing in and leading his own band. As his reputation endeavors and guided his interests in ophthalmology, increased, he began booking other musicians for professional beginning with a visit to the New York Lighthouse for the engagements, and in 1924 founded Music Corporation of Blind in the late 1950s. Deeply moved, Doris Stein urged her America (MCA). Shortly thereafter, he gave up the practice husband to “do something!” From that passionate beginning of medicine to concentrate on this enterprise. Within 10 came a broad base of programs that catalyzed eye research. years, MCA represented most of the great name bands and corporate activities began to extend to representation of film Doris Stein was a major force in this vision renaissance. stars, directors, writers, and musical artists. MCA entered the She served as an officer and director of Research to Prevent promising new field of television at its inception, eventually Blindness, personally leading the appeal to establish more acquiring the Universal City property, Universal Pictures, resources for investigations into eye diseases. She suggested and other enterprises to become pre-eminent in the that Jules Stein assume the principal role in the creation entertainment industry. of an eye institute at UCLA, and her unflagging enthusiasm nurtured the Institute’s development as a unique provider Throughout his phenomenally successful career, Jules Stein of every facet of vision research and patient care. Serving as maintained a strong interest and emotional investment in Trustee, she focused special attention on Institute initiatives medicine, particularly his own field of ophthalmology. In the to combat blindness throughout the world. She devoted her late 1950s, urged by his wife, Doris, he chose to direct his last days, until her death in 1984, to the development of an considerable talents to blindness prevention. The result expansion and companion building for eye research. In 1989, was a concert of ideas and achievements that encompassed dedication ceremonies were held for the Doris Stein Eye philanthropy, government, and academic medicine. Research Center. By his efforts, Research to Prevent Blindness was created, now With grace, vision, and meaningful action, Doris Stein recognized as the world’s leading voluntary organization in enhanced the lives of all privileged to know her, stimulated a support of studies of the eye and its diseases. Jules Stein was cascade of progress in eye research, co-founded the Institute largely responsible for the passage of legislation to establish with its boundless scientific potential, and extended the the National Eye Institute as a separate entity in the National miracle of sight to untold numbers of people. Institutes of Health. Under his leadership, the Jules Stein Eye vi FacultyBoard of Trustees BOARD OF TRUSTEES The Jules Stein Eye Institute Board of Trustees was established for the Institute, adoption of measures to facilitate recruitment in 1977 to ensure the Institute’s orderly growth and of the world’s finest vision scientists, allocation of funds for development. The Board meets regularly during the year, with the purchase of vision research equipment, and each Trustee providing his/her unique counsel. Collectively, recommendations for facilities expansion programs. their invaluable contributions have included fiscal planning Current Members Bartly J. Mondino, MD Nelson C. Rising, Esq. Director Chairman and CEO Jules Stein Eye Institute Rising Realty Partners, LLC 1994–present 2004–present Ronald L. Olson, Esq. George A. Smith, Esq. Partner Consultant Munger, Tolles, and Olson 1992–present 1995–present Gerald H. Oppenheimer Katrina Vanden Heuvel President Publisher and Editor Gerald Oppenheimer The Nation Magazine Family Foundation 1984–present President Systems Design Associates 1992–present Andrea L. Rich, PhD Casey Wasserman Retired President, Chief Executive Chief Executive Officer Officer and Director The Wasserman Foundation Los Angeles County Museum of Art 1998–present Executive Vice Chancellor Emerita UCLA 2007–present Executive Committee vii EXECUTIVE COMMITTEE Director, Jules Stein Eye Institute Vice-Chairmen, UCLA Department of Ophthalmology Chairman, UCLA Department of Ophthalmology Sherwin J. Isenberg, MD Bartly J. Mondino, MD Arthur L. Rosenbaum, MD Associate Directors, Jules Stein Eye Institute Chief Administrative Officer, Jules Stein Eye Institute Wayne L. Hubbell, PhD Jonathan D. Smith Gabriel H. Travis, MD Jules Stein Eye Institute Executive Committee: (sitting from left to right) Drs. Gabriel Travis, Arthur Rosenbaum, Sherwin Isenberg, and Bartly Mondino; (standing from left to right) Mr. Jonathan Smith and Dr. Wayne Hubbell. viii FacultyFacilities FACILITIES The facilities of the Jules Stein Eye Institute comprise two free- standing structures of architectural note. The five-story Jules Stein Eye Institute building, occupying 110,000 square feet, is of neo-classical design. It is the original facility, constructed in 1966. An expansion and companion building, the Doris Stein Eye Research Center, followed in 1989. It is a four-story, red granite structure, occupying 67,000 square feet, and connecting with the Jules Stein