Senior Scientific Team

SENIOR SCIENTIFIC TEAM LabCorp® provides leading-edge diagnostic tests and services through a network of primary clinical laboratories and its specialty testing group. With scientific expertise in esoteric testing, genomics, clinical and anatomic pathology, and a commitment to comprehensive and high quality laboratory services, LabCorp delivers, accurate results for improved patient care. LabCorp clients include physicians, government agencies, managed care organizations, hospitals, clinical labs, and pharmaceutical companies. LabCorp employs a large scientific staff that includes MDs and PhDs available for testing support and consultation. This document includes a subset of key medical and scientific directors dedicated to LabCorp’s esoteric and genomic testing. Chief Medical Officer Coagulation, Core Lab Identity Benjamin A. Nye, MT(ASCP)SH Uwe Heine, PhD Mark E. Brecher, MD André A. Valcour, PhD George C. Maha, JD, PhD Chief Scientific Officer Coagulation, Esoteric Immunohematology Marcia Eisenberg, PhD Dorothy M. (Adcock) Funk, MD Mark E. Brecher, MD Laura McClannan Cytogenetics Medical and Scientific Directors Peter Papenhausen, PhD Immunohistochemistry Mark E. Brecher, MD Bing Huang, MD, PhD Kim Dickinson, MD, MBA, MPH Kim Dickinson, MD, MBA, MPH Evelyn Vazquez Marcia Eisenberg, PhD Esoteric Immunoassay James K. Fleming, PhD Kelly Y. Chun, PhD Immunology André A. Valcour, PhD Joe Adams Divisional Medical Directors Esoteric Microbiology Infectious Disease Immunology James B. Amberson, MD Barbara A. Body, PhD Mary Ann Meiser Alicia Carter, MD Kyle L. Eskue, MD Flow Cytometry Manual Microbiology Sean E. Farrier, MD Janita Hughes Douglas Howard David Engler, PhD Araceli B. Reyes, MD Horacio G. Vall, PhD Kevin M. Harvey, PhD Nathan Thomas Scanzillo, PhD Rita Stainback Praveena Yetur, MD Fluorescent in situ Hybridization Kathleen E. Richkind, PhD Mass Spectrometry Discipline Directors James H. Tepperberg, PhD Russell Phillip Grant, PhD Gregory Clark Janis Allergy Forensic Toxicology André A. Valcour, PhD Glynn Chaney Microarray Jennifer A Collins, PhD Stuart Schwartz, PhD Anatomic Pathology Prabhakaran Koteel, PhD James Amberson, MD Molecular Genetics and Alicia Carter, MD Hematology Genomics Betty M. Garvin Burns Narasimhan Nagan, PhD Biochemical Genetics Suzette Huguenin, PhD Hematopathology Molecular Infectious Disease Philip Wyatt, MD, PhD Cherie Hilborn Dunphy, MD Charles P. Cartwright, PhD Ronald Wayne Thomason, MD Jeannette M. Whitcomb, PhD Clinical Toxicology Histology/Cytology Ray Gegen Alicia Carter, MD Molecular Microbiology Karla B. Walker, PharmD Tiea L. Kesler Barbara A. Body, PhD Melinda B. Nye, PhD 1 SENIOR SCIENTIFIC TEAM Molecular Oncology Routine Chemistry Special Chemistry/Endocrinology Li Cai, PhD Thomas S. Herman, PhD Donald Walt Chandler, PhD Henry Y. Dong, MD, PhD Nathan Thomas Scanzillo, PhD Randolph M. Young, PhD Quality Control Satellite Labs and Waived Testing Specimen Quality Alexander L. Katayev, MD James Kyle Farquhar, PhD Mark Sharp Randolph M. Young, PhD Frank Ryan, PhD H. Thomas Spillman, PhD Chief Medical Officer Mark E. Brecher, MD – Chief Medical Officer and Senior Vice President, LabCorp; Discipline Director, Immunohematology, LabCorp Office location: Burlington, NC | Office telephone: 336 436-5049 | E-mail address: [email protected] Dr Brecher is board certified in anatomic and clinical pathology and in blood banking and transfusion medicine. He earned his medical degree at the University of Chicago Pritzker School of Medicine, where he also completed residency training in anatomic and clinical pathology. He completed a blood banking and transfusion medicine fellowship at the Mayo Clinic. Dr Brecher is a leader in the field of pathology. Prior to joining LabCorp, he served on the faculty of the Mayo Clinic Department of Laboratory Medicine and Pathology (1988 to 1992) and as vice chair of the Department of Pathology and Laboratory Medicine at the McLendon Clinical Laboratories, University of North Carolina Hospitals (1992 to 2009). Presently, he is an adjunct professor of pathology and laboratory medicine at the University of North Carolina. Dr Brecher’s research has been published in a wide variety of journals, including the New England Journal of Medicine, The Lancet, and the Mayo Clinic Proceedings. He is a member of the editorial boards of Transfusion and Blood Therapies in Medicine and an associate editor of the Journal of Clinical Apheresis. He is the immediate past chair of the Department of Health and Human Services Advisory Committee on Blood Safety and Availability and a past president of the American Society for Apheresis. Dr Brecher is a member of the American College of Pathologists, the American Association of Blood Banks, the American Society of Hematology, the American Society for Apheresis, and the International Society of Cellular Therapy. Chief Medical Officer Marcia Eisenberg, PhD – Senior Vice President and Chief Scientific Officer, LabCorp Office location: Research Triangle Park, NC | Office telephone: 919-361-7760 | E-mail address: [email protected] Dr Eisenberg earned a PhD in molecular biology from the University of Kentucky. She was a National Institutes of Environmental Health Sciences fellow in Research Triangle Park, NC. Dr Eisenberg has been a member of the Federal Bureau of Investigation’s Technical Working Group on DNA Analysis Methods, and she was an appointed member of the National DNA Advisory Board during its lifespan. She has been recognized and honored for her contributions to the advancement of forensic DNA testing. She currently holds certification in molecular genetics and molecular oncology, forensic DNA testing, and paternity testing from the New York State Department of Health. Dr Eisenberg has been employed by LabCorp for 21 years. She was hired to convert the then-current diagnostic testing to polymerase chain reaction (PCR)-based testing, which had recently been acquired by Roche Biomedical Laboratories, Inc. Her key areas of expertise include test development, optimization, and automation; review of new tests, technologies, and platforms; and working with partners to transform their intellectual property into viable diagnostic assays. 2 SENIOR SCIENTIFIC TEAM Medical and Scientific Directors Mark E. Brecher, MD – Chief Medical Officer and Senior Vice President, LabCorp; Discipline Director, Immunohematology, LabCorp Office location: Burlington, NC | Office telephone: 336 436-5049 | E-mail address: [email protected] See Dr Brecher’s biographical sketch on page 2. Kim Dickinson, MD, MBA, MPH – Medical Director, Integrated Oncology; Discipline Director, Immunohistochemistry, LabCorp Office location: Irvine, CA | E-mail address: [email protected] Dr Dickinson is board certified in anatomic and clinical pathology. She received her medical degree from Hahnemann University in Philadelphia and completed her residency training and a surgical pathology fellowship at Los Angeles County-University of Southern California (LAC-USC). Dr Dickinson sits on the board for the California Society of Pathologists and is a member of the College of American Pathology, the American Society of Clinical Pathologists, and the Digital Pathology Association. Marcia Eisenberg, PhD – Senior Vice President and Chief Scientific Officer, LabCorp Office location: Research Triangle Park, NC | Office telephone: 919-361-7760 | E-mail address: [email protected] See Dr Eisenberg’s biographical sketch on page 2. James K. Fleming, PhD Vice President and Director, Department of Science and Technology, LabCorp Office location: Burlington, NC | Office telephone: 336-436-2375 | E-mail address: [email protected] Dr Fleming is board certified in clinical biochemistry. He earned a PhD in clinical pathobiology from the Medical University of South Carolina, where he also completed a postdoctoral fellowship in clinical biochemistry. Dr Fleming has been part of the LabCorp organization since 1989, serving as vice president and director of the Department of Science and Technology and an associate director responsible for the administrative and technical operations of the Special Chemistry department at LabCorp’s Esoteric Testing laboratory. His current responsibilities include the determination of core laboratory diagnostic testing and platform decisions for LabCorp and the ongoing quality vigilance associated with all testing. These decisions incorporate improvements in workflow efficiencies through platform consolidations, cost containment strategies, and early assessment and adoption of cutting-edge technology. Previously, Dr Fleming held an appointment as an associate professor at the Medical University of South Carolina and as a consultant to the government of Burma to upgrade the laboratory systems throughout that country. He served as member of the North Carolina Legislative Task Force on the Early Detection of Kidney Disease and on the Board of Registry. He once chaired the Clinical Chemistry Examination Committee. Dr Fleming currently serves as a member of the Laboratory Working Group of the National Institutes of Health National Kidney Disease Education Program and as an invited lecturer for the American Society of Clinical Pathologists for numerous seminars and workshops. Dr Fleming is a fellow of the Academy of Clinical Biochemistry, a clinical scientist with the American Society of Clinical Pathology, a member of the American Association for Clinical Chemistry, and a professional member of both the American Diabetes Association and the American Heart Association.

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