Of Inhalant Abuse: an Update
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Understanding Solvents: Part I
Understanding Solvents: Part I Solvents make stains and finishes work. You will never feel really comfortable with finishing until you have an understanding of solvents. Following is an overview of each of the most commonly available solvents. For a deeper understanding that better relates all the finish solvents to each other, see Understanding Solvents, Part II. For an explanation of lacquer thinner, which is composed of about half- a-dozen individual solvents, see Lacquer Thinner. Petroleum Distillates and Turpentine Petroleum distillates are distillations of petroleum. They include mineral spirits (informally referred to as “paint thinner”), naphtha, toluene, xylene and some “turpentine substitutes” such as turpatine and T.R.P.S. Their primary use in wood finishing is for thinning waxes, oils, and varnishes, including polyurethane varnish, and for cleaning brushes. Petroleum distillates are also used to remove oil, grease and wax. Turpentine is a distillation of pine-tree sap. Before the mid-twentieth century, turpentine was widely used as a thinner and clean-up solvent for oil paint and varnish and also as an oil, grease and wax remover. With the growth of the automobile industry and its need for petroleum products, a large number of petroleum solvents were introduced and these have almost entirely replaced turpentine because they are less expensive and have less unpleasant odor. The only sector in which turpentine is still used in any quantity is fine arts. To produce solvents from petroleum, the liquid is heated and gases are taken off and condensed as the temperature increases. The process is called distillation—and thus, petroleum distillates. -
Drug Use Sequencing and Kandel's Gateway Hypothesis John Reid Clemson University, [email protected]
Clemson University TigerPrints All Theses Theses 8-2008 Drug Use Sequencing and Kandel's Gateway Hypothesis John Reid Clemson University, [email protected] Follow this and additional works at: https://tigerprints.clemson.edu/all_theses Part of the Sociology Commons Recommended Citation Reid, John, "Drug Use Sequencing and Kandel's Gateway Hypothesis" (2008). All Theses. 447. https://tigerprints.clemson.edu/all_theses/447 This Thesis is brought to you for free and open access by the Theses at TigerPrints. It has been accepted for inclusion in All Theses by an authorized administrator of TigerPrints. For more information, please contact [email protected]. DRUG USE SEQUENCING AND KANDEL'S GATEWAY HYPOTHESIS A Thesis Presented to the Graduate School of Clemson University In Partial Fulfillment of the Requirements for the Degree Master of Science Applied Sociology by John Matthew Reid August 2008 Accepted by: Dr. Brenda Vander Mey, Committee Chair Dr. Douglas Kinly Sturkie Dr. Margaret Tina Britz i ABSTRACT This thesis tests the hypothesis by Kandel (1975) that there is a specific sequence of drug use that users follow. Using the same scalogram analysis technique utilized by Kandel in her original Gateway Hypothesis study, a distinct sequence of use was discovered. This thesis is based on the National Survey on Drug Use and Health (2005). This study confirmed Kandel’s earlier findings in that this study determined that there is a sequence of drug use. The current study also confirms Kandel’s position that licit drugs precede the use of illicit drugs. This study’s findings differ from those of Kandel, however, in that tobacco and not alcohol was found to be the first drug of experimentation. -
A Molecular Basis for Nicotine As a Gateway Drug
The new england journal of medicine special article shattuck lecture A Molecular Basis for Nicotine as a Gateway Drug Eric R. Kandel, M.D., and Denise B. Kandel, Ph.D. From the Howard Hughes Medical Insti- n the historic occasion of the 122nd Shattuck Lecture and tute (E.R.K.), Kavli Institute for Brain Sci- the 200th anniversary of the New England Journal of Medicine, we chose to ad- ence (E.R.K.), and the Departments of Neuroscience (E.R.K.) and Psychiatry Odress a topic that is at once scientific and personally historic. In recent (E.R.K., D.B.K.), College of Physicians debates over legalizing marijuana, from all-out acceptance in Colorado to narrow and Surgeons, and Mailman School of decriminalization in Maryland, the scientific question of the role of marijuana as a Public Health (D.B.K.), Columbia Univer- sity, and the New York State Psychiatric gateway drug (i.e., a drug that lowers the threshold for addiction to other agents) Institute (D.B.K.) — all in New York. Ad- has loomed large. Both opponents and proponents of legalization have distorted dress reprint requests to Dr. E. Kandel at what science does and does not tell us — and both sides have overlooked the im- the Department of Neuroscience, Col- lege of Physicians and Surgeons, Colum- portance of nicotine as a gateway drug. bia University, 1051 Riverside Dr., Unit Epidemiologic studies have shown that nicotine use is a gateway to the use of 87, New York, NY 10032, or at erk5@ marijuana and cocaine in human populations. -
2016 and Over 4,000 Research Scientists, 168 Scientific Leaders and 60,000 Was Our Leader and Guiding Light, Providing Inspiration and Moti- Pression
INVEST IN MENTAL HEALTH ANNUAL REPORT 2 0 1 6 Dear Brain & Behavior Research Foundation Supporters: From mental illness to mental health–30 years of achievements by tremendous impact on psychiatric research and treatment. Connie problems improves symptoms of some patients with refractory de- The Foundation is proud of our accomplishments in 2016 and over 4,000 research scientists, 168 scientific leaders and 60,000 was our leader and guiding light, providing inspiration and moti- pression. In a study of patients with treatment-resistant depression, we are excited to focus on the promising path of discovery. With donors. We are proud to present you with our 2016 annual report vation to all who ever had the honor and privilege of knowing and about two thirds had metabolic deficiencies that affect the brain’s your sustained commitment, we will accelerate the funding of our and invite you to invest in mental health. working with her. She will be dearly missed by us all. But her legacy ability to produce neurotransmitters. Dr. Pan’s research found Grants and continue to lead the field with breakthroughs that continues with each new scientist which we support and each new that patients’ depression symptoms declined significantly when improve the lives of those living with mental illness. Thank you for Since 1987, the Brain & Behavior Research Foundation has invest- discovery which improves people’s lives. their metabolic problems were treated. Some of the patients even continuing the journey with us. ed in the future. We support the innovative brain and behavior reached remission. The most common of the deficiencies observed research today which will lead to new treatments and eventual While we are proud of our accomplishments, there is still much in the participants was in levels of cerebral folate, which is treat- Sincerely, cures in the future. -
Substance Abuse by Adolescents in 1977 with 499 French Adolescents
In a country like Israel, which is deeply committed to the main sources of infection, among them active foci achievement of an expanded immunization program, the still present in the neighboring territories. effort to reach this objective should be weighed within the national program aimed at elimination of the diseases References .................................. controlled by mass immunization. Analysis of present achievements clearly shows that measles, together with 1. Swartz, T. A., and Klingberg, W.: Routine measles immu- poliomyelitis and rubella, deserves to be included among nization in Israel: A three-year clinical and serologic follow- up. In International conference on application of vaccines the first priorities of a program whose objective is elim- against viral, rickettsial, and bacterial diseases of man, ination of clinical disease. Washington, D.C., 14-18 December 1970. Pan American Health Organization, Washington, D.C., 1971, pp. Conclusions 265-268. 2. Centers for Disease Control: Measles Surveillance Report No. 11, 1977-1981. Atlanta, Ga., September 1982. A 17-year-old immunization program has created the 3. Health and Welfare Canada: Measles in Canada. Canada basis for elimination of measles in Israel, provided that Diseases Weekly Report 9-25: 29-101 (1983). (a) the control policy is adapted to the seroepidemiology 4. World Health Organization: Measles surveillance. Weekly of the infection, and (b) a concentrated logistic effort is Epidemiol Record 58: 85-86 (1983). mounted in the period preceding the next expected epi- 5. Hopkins, D. R., Hinman, A. R., Kaplan, J. E, and Lane, J. M.: The case for global measles eradication. Lancet 1: demic. Under this effort: 1936-1938, June 19, 1982. -
Paint Thinner Analysis Utilizing Headspace GC-MS 17
LAAN-E-MS-E017 GCMS Gas Chromatograph Mass Spectrometer Paint Thinner Analysis Utilizing Headspace GC-MS 17 Paint thinners, which are utilized to lessen the viscosity of paints, consist primarily of toluene, and contain other substances such as ethyl acetates and alcohols. As these compounds have anesthetic and excitatory properties, “paint sniffing”, or abuse by intentional inhalation, has become a social problem, leading to regulations targeting the inhalation of paint thinner for such purposes [1, 2]. Since GC-MS systems are often utilized in place of GC in scientific crime detection, this experiment investigated the ability of Headspace GC-MS to measure ethyl acetate, toluene, and methanol. Experiment Samples Samples consisted of commercially-available paint thinner; samples of paint thinner and water in 2 separate phases, with either water or paint thinner as the primary ingredient; commercially-available adhesive; and tissue paper with paint thinner added. Pretreatment 5 μL of commercially-available paint thinner was placed in a headspace vial (22 mL), which was then sealed with a headspace cap (aluminum cap: butyl rubber/PTFE). Samples of paint thinner mixed with water, as well as paint thinner and water in 2 separate phases, were agitated, after which 5 μL samples were quickly extracted and placed in headspace vials. The vials were then sealed with headspace caps. Approximately 50 mg to 100 mg of commercially-available adhesive was placed in a headspace vial, which was then sealed with a headspace cap. In addition, 5 μL of commercially-available paint thinner was added to a sheet of tissue paper. The tissue paper was placed in a headspace vial, which was then sealed with a headspace cap, creating a sample consisting of tissue paper with paint thinner added. -
How to Determine If Solvents Are a Hazardous Waste
Solvents in the Workplace How to Determine If They Are Hazardous Waste September 2016 Version 2 1 DISCLAIMER This guide is not a regulation, nor can it be considered a substitute for the actual regulations, related laws, and applicable court decisions. This guide presents EPA’s interpretation of the federal RCRA hazardous waste regulations; the reformatted Code of Federal Regulations (CFR) language in this guide is not a substitute for the CFR or its requirements. Note to Reader: Version 2 corrects typographical errors, a few caused by formatting problems in Table 1, further clarifies solvents that still can be used are nevertheless considered to be a spent material if they are instead sent for reclamation, and further describes and clarifies the discussion of F003 solvents and land disposal restriction requirements. This version also adds a Question and Answer on substituting alternative or non-hazardous solvents for hazardous solvents as effective substitutes, and clarifies the air emission requirements for solvents recycled on-site. 2 Table of Contents About this guide ............................................................................................................................................ 4 1.What are solvents and how are they used?................................................................................................. 5 2. Why do I need to know about solvents? ................................................................................................... 5 3. Do I use solvents in my facility? .............................................................................................................. -
DOCUMENT RESUME ED 222 832 CG 016 300 AUTHOR Lettieri, Dan
DOCUMENT RESUME ED 222 832 CG 016 300 AUTHOR Lettieri, Dan J., Ed.; Ludford, Jacqueline P., Ed. TITLE Drug Abuse and the American Adolescent. NIDA Research Monograph 38. A RAUS Review Report. INSTITUTION National Inst. on Drug Abuse (DHHS), Rockville, Md. Div. of Research. REPORT NO DHHS-ADM-81-1166 PUB DATE 8 Sep 80 NOTE 140p.; Papers presented at the Research Analysis and Utilization System (RAUS) Review Conference on Drug Abuse and the American Adolescent (Rockville, MD, September 8, 1980). AVAILABLE FROMSuperintendent of Documents, U.S. Government Printing Office, Washington, DC 20402. PUB TYPE Collected Works - Conference Proceedings (021) Reference Materials - Bibliographies (131) Reports Research/Technical (143) EDRS PRICE MF01/PC06 Plus Postage. DESCRIPTCRS *Adolescents; Biomedicine; Cohort Analysis; *Delinquent Behavior; Drinking; *Drug Abuse; Individual Differences; Literature Reviews; Longitudinal Studies; *Peer Influence; Personality Traits; *Predictor Variables; Secondary Education; *Youth Problems IDENTIFIERS *Epidemiology ABSTRACT This report reviews five studiei-dealing with drug abuse and adolescence and presents an overview of the social changes which have contributed to the increased use of marijuana and other illicit drugs. The importance of the longitudinal study as a research tool is emphasized in describing the research projects that dealwith the epidemiology of drug use, personality and sociodemographic factors, peer influence, the relationship between delinquency and drug use, and its biomedical consequences. The report closes with an executive summary, discussion, and suggestions for further research. An annotated list of NIDA (National Institute of DrugAbuse) research monographs is included. (JAC) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** Drug Abuse and the American Adolescent Editors: Dan J. -
Solvents/Inhalants Information for Health Professionals
Solvents/Inhalants Information for Health Professionals Introduction Inhalants compromise a wide variety of vapours, gases, and aerosols that can be inhaled to induce psychoactive (mind-altering) effects. Unlike other drugs, inhalants are available as legal products with low costs and wide availability. Examples include commercial products such as nail polish remover, hair sprays, lighter fluid, cleaning fluids, vegetable frying pan lubricants, and spray paints. These chemicals can be sniffed or inhaled because they are gaseous at room temperature and pressure. “Inhalant” is a general term that includes all substances used in this way. Most inhalants are volatile solvents, which are liquids that easily vaporize at room temperature and can contain many different chemicals that may be psychoactive. The majority of these solvents are produced from petroleum and natural gas. They have an enormous number of industrial, commercial and household uses, and are found in automobile fuels, cleaning fluids, toiletries, adhesives and fillers, paints, paint thinners, felt-tip markers, and many other products. In addition to volatile solvents, aerosols (hair spray, paint spray) can be abused as inhalants. Other inhalants include the nitrites (amyl and butyl, “poppers”, “Rush”) and gases such as the anesthetics nitrous oxide (laughing gas) and ether. Inhalants can be breathed in through the nose or mouth in a variety of ways, including spraying aerosols directly into the nose or mouth, “sniffing” or "snorting” fumes from containers, inhaling from balloons filled with nitrous oxide, “huffing” from an inhalant-soaked rag stuffed in the mouth, or “bagging”- pouring the substance over a cloth or into a plastic bag and breathing in the vapours. -
Is Cannabis a Gateway Drug? Key Findings and Literature Review
U.S. Department of Justice Office of Justice Programs National Institute of Justice National Institute of Justice Is Cannabis a Gateway Drug? Key Findings and Literature Review Wm. Nel, MSc, Researcher Judy Wang, PhD, Researcher November 2018 A Report Prepared by the Federal Research Division, Library of Congress, Under an Interagency Agreement with the Office of the Director, National Institute of Justice, Office of Justice Programs, U.S. Department of Justice. NCJ 252950 U.S. Department of Justice Office of Justice Programs 810 Seventh St. N.W. Washington, DC 20531 David B. Muhlhausen, Ph.D. Director, National Institute of Justice This and other publications and products of the National Institute of Justice can be found at: National Institute of Justice Strengthen Science • Advance Justice nij.ojp.gov Office of Justice Programs Building Solutions • Supporting Communities • Advancing Justice O J P.gov The National Institute of Justice is the research, development, and evaluation agency of the U.S. Department of Justice. NIJ’s mission is to advance scientific research, development, and evaluation to enhance the administration of justice and public safety. The National Institute of Justice is a component of the Office of Justice Programs, which also includes the Bureau of Justice Assistance; the Bureau of Justice Statistics; the Office for Victims of Crime; the Office of Juvenile Justice and Delinquency Prevention; and the Office of Sex Offender Sentencing, Monitoring, Apprehending, Registering, and Tracking. Opinions or conclusions expressed in this paper are those of the authors and do not necessarily reflect the official position or policies of the U.S. Department of Justice. -
17Th European Society for Biomedical Research on Alcoholism Congress 21-24 September 2019, Lille – Invited Talks and Symposia Abstracts
Directeur de la rédaction Pr François Paille Rédacteur en chef Pr Amine Benyamina Rédacteurs associés Dr Philippe Batel Dr Ivan Berlin Dr Laurent Karila Pr Michel Lejoyeux Pr Mickaël Naassila Rédactrice Sciences humaines Pr Myriam Tsikounas Rédactrice Sciences psychologiques Pr Isabelle Varescon-Pousson Comité de rédaction Pr Georges Brousse Pr Olivier Cottencin Dr Michel Craplet Pr Jean-Bernard Daeppen Dr Jean-Michel Delile Pr Maurice Dematteis Dr Claudine Gillet th Dr Geneviève Lafaye 17 European Society for Biomedical Research Pr Michel Reynaud Dr Alain Rigaud Dr Marc Valleur on Alcoholism Congress Directeur de la publication Pr Mickael Naassila 21-24 September 2019, Lille Comité scientifique Pr Jean Adès Pr Thomas F. Babor Pr Jean-Louis Balmès Pr Maurice Bazot Dr Mats Berglund Pr Jacques Besson Pr Jean-Pierre Blayac Pr Jonathan D. Chick Mme Marie Choquet Pr Philippe de Witte Pr Michel Escande Pr Claude Got Dr Antoni Gual Pr Momar Gueye Pr Roger Henrion Pr Denise Kandel Pr Michel Le Moal Pr Karl Mann Mme Véronique Nahoum-Grappe Dr José Maria Neves Cardoso Pr Philippe-Jean Parquet Pr Jean-Louis Pedinielli Pr Falvio Poldrugo Pr Bernard Roques Pr John A. Talbott Pr Jean-Luc Vénisse Pr Lars von Knorring Pr Jacques Weill Pr Jean-Jacques Yvorel ISSN 2554-4853 Trimestriel Société Française PRINCEPS Éditions SEPTEMBRE-DÉCEMBRE 2019 - Tome 41, n° 3-4 d’Alcoologie !BSTRACTS CONGRÈS Pr Mickael Naassila* * President 17th ESBRA Meeting 17th European Society for Biomedical Research on Alcoholism congress 21-24 September 2019, Lille – Invited talks and Symposia abstracts Invited talks forward, such as combining training with neurostimulation. -
Cocaine Use in America: Epidemiologic and Clinical Perspectives
DOCUMENT RESUME ED 268 463 CG 019 022 AUTHOR Kozel, Nicholas J., Ed.; Adams, Edgar H., Ed. TITLE Cocaine Use in America: Epidemiologic and Clinical Perspectives. National Institute on Drug Abuse (NIDA) Research Monograph Series 61. INSTITUTION National Inst. on Drug Abuse (DHHS/PHS), Rockville, Md. REPORT NO DHHS-ADM-85-1414 PUB DATE 85 NOTE 243p. AVAILABLE FROMSuperintendent of Documents, U.S. Government Printing Office, Washington, DC 20402. PUB TYPE Reports - Research/Technical (143) -- Collected Works General (020) EDRS PRICE MF01/PC10 Plus Postage. DESCRIPTORS *Adolescents; *Behavior Patterns; *Drug Abuse; *Illegal Drug Use; Individual Characteristics; *Trend Analysis; *Young Adults IDENTIFIERS *Cocaine ABSTRACT This monograph is based on papers presented at a technical review of patterns of cocaine use in the United States which was held in 1984. The foreword by Jerome H. Jaffe acknowledges that, over the past 10 years, cocaine has become a major public health threat in this country. Papers contained in this monograph include: (1) "Cocaine Use in America: Introduction and Overview" by Edgar H. Adams and Nicholas J. Kozel; (2) "Cocaine Use in the United States: In a Blizzard or Just Being Snowed?" by Richard R. Clayton; (3) "A Decade of Trends in Cocaine Use in the Household Population" by Herbert I. Abelson and Judith Droitcour Miller; (4) "Cocaine Use Among American Adolescents and Young Adults" by Patrick M. O'Malley, Lloyd D. Johnston, and Jerald G. Bachman; (5) "Cocaine Use in Young Adulthood: Patterns of Use and Psychosocial Correlates" by Denise B. Kandel, Debra Murphy, and Daniel Karus; (6) "Patterns and Consequences of Cocaine Use" by Dale D.