VNN2 Antibody Cat. No.: 23-444

VNN2 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion containing a sequence corresponding to amino acids 270-493 IMMUNOGEN: of human VNN2 (NP_004656.2).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:500 - 1:2000

POSITIVE CONTROL: 1) Raji

2) Mouse brain

3) Rat brain

PREDICTED MOLECULAR Observed: 33kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

September 23, 2021 1 https://www.prosci-inc.com/vnn2-antibody-23-444.html CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: VNN2

FOAP-4, GPI-8vascular non-inflammatory molecule 2, Vannin 2, glycosylphosphatidyl ALTERNATE NAMES: inositol-anchored protein GPI-8pantetheinase

GENE ID: 8875

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This product is a member of the Vanin family of that share extensive sequence similarity with each other, and also with . The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, BACKGROUND: which may play a role in oxidative-stress response. The encoded protein is a GPI- anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin on 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 23, 2021 2 https://www.prosci-inc.com/vnn2-antibody-23-444.html