VNN2 Antibody Cat. No.: 23-444 VNN2 Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human, Mouse, Rat Recombinant fusion protein containing a sequence corresponding to amino acids 270-493 IMMUNOGEN: of human VNN2 (NP_004656.2). TESTED APPLICATIONS: WB APPLICATIONS: WB: ,1:500 - 1:2000 POSITIVE CONTROL: 1) Raji 2) Mouse brain 3) Rat brain PREDICTED MOLECULAR Observed: 33kDa WEIGHT: Properties PURIFICATION: Affinity purification CLONALITY: Polyclonal ISOTYPE: IgG September 23, 2021 1 https://www.prosci-inc.com/vnn2-antibody-23-444.html CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles. Additional Info OFFICIAL SYMBOL: VNN2 FOAP-4, GPI-8vascular non-inflammatory molecule 2, Vannin 2, glycosylphosphatidyl ALTERNATE NAMES: inositol-anchored protein GPI-8pantetheinase GENE ID: 8875 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, BACKGROUND: which may play a role in oxidative-stress response. The encoded protein is a GPI- anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 23, 2021 2 https://www.prosci-inc.com/vnn2-antibody-23-444.html.