ROUNDUP ORIGINAL Herbicide SKIN PROTECTION: Wear Appropriate Protective MSDS NUMBER: S00012114 Before Reuse

MATERIAL SAFETY DATA SHEET. Database and format copyright © 1998 by C&P Press. All rights reserved. 1 ® ROUNDUP ORIGINAL 4. FIRST AID MEASURES 8. EXPOSURE CONTROLS/PERSONAL PROTEC- TION Herbicide IF IN EYES: Immediately hold eyelids open and flush with plenty of water. Get medical attention. EYE PROTECTION: Wear chemical splash goggles 1. CHEMICAL PRODUCT AND COMPANY IDENTI- during mixing/pouring operations or other activities in IF ON SKIN: Immediate first aid is not likely to be ® FICATION required. However, this material can be removed with which eye contact with undiluted ROUNDUP ORIGI- ® soap and water. Wash heavily contaminated clothing NAL Herbicide is likely to occur. PRODUCT NAME: ROUNDUP ORIGINAL Herbicide SKIN PROTECTION: Wear appropriate protective MSDS NUMBER: S00012114 before reuse. IF INHALED: Remove individual to fresh air. If not clothing to prevent skin contact. Applicators and other DATE: November, 1997 handlers must wear long-sleeved shirt, long pants, EPA Reg. No.: 524-445 breathing, give artificial respiration, preferably mouth- to-mouth. Get medical attention shoes plus socks and protective eyewear. Follow man- MONSANTO COMPANY, 800 N. LINDBERGH BLVD., ufacturer’s instructions for cleaning/maintaining PPE. IF SWALLOWED: This product will cause gastroin- ST. LOUIS, MO 63167 If no such instructions for washables, use detergent testinal tract irritation. Immediately dilute by swallow- FOR MEDICAL EMERGENCY CALL (collect calls ac- and hot water. Keep and wash PPE separately from ing water or milk. Get medical attention cepted): 314-694-4000 other laundry. FOR CHEMICAL EMERGENCY, SPILL LEAK, FIRE, NOTE: For additional human emergency first aid or RESPIRATORY PROTECTION: treatment guidance, call collect, anytime, day or night EXPOSURE, OR ACCIDENT Call CHEMTREC - Day For Handling of the Undiluted Product: Undiluted (314) 694-4000. or Night - 1-800-424-9300 Toll free in the continental ROUNDUP® ORIGINAL Herbicide is not likely to be U.S., Hawaii, Puerto Rico, Canada, Alaska, or Virgin present an airborne exposure concern during normal Islands. For calls originating elsewhere: 703-527-3887 5. FIRE FIGHTING MEASURES handling. If there is an accidental discharge of the ma- (collect calls accepted) FLASH POINT: None terial during manufacture or handling that produces a For additional non-emergency information, call: 800- METHOD: Pensky-Mariens heavy vapor or mist, workers should use NIOSH/MSHA 332-3111 AUTOIGNITION TEMPERATURE: Not determined. approved equipment. In work situations where an air purifying respirator is appropriate to be used, use of 2. COMPOSITION/INFORMATION ON INGREDI- HAZARDOUS PRODUCTS OF COMBUSTION: CO2, a full face respirator equipped with purifying elements ENTS CO, NOx for protection against organic vapor and dust/mist ap- EXTINGUISHING MEDIA: In case of fire, use water proved for pesticides is recommended. Use cartridges (flood with water), dry chemical, CO2, or alcohol foam. COMPONENT CAS NO. %BYWEIGHT with MSHA/NIOSH approval number TC-23C or canis- UNUSUAL FIRE AND EXPLOSION HAZARDS: None ter with MSHA/NIOSH approval number TC-14G. Full Active Ingredient: FIRE FIGHTING EQUIPMENT: Fire fighters and others facepiece replaces the need for chemical goggles. Ob- Glyphosate, N-(phos- exposed to products of combustion should wear self- phonomethyl)glycine, serve respirator use limitations specified by the manu- in the form of its contained breathing apparatus. Equipment should be facturers. Respiratory protection programs must com- isopropylamine salt 1071-83-6 41.0 thoroughly decontaminated after use. ply with 29 CFR §1910.134. Inert Ingredients: 59.0 For Application of Product Diluted in accordance with 100.0 6. ACCIDENTAL RELEASE MEASURES label instructions: Respirators are not required for ap- plications of use - dilution’s of ROUNDUP® ORIGINAL Inert Ingredient Component Contain large spills with dikes and transfer the material Herbicide. Ethoxylated to appropriate containers for reclamation or disposal. Tallowamines * 61791-83-6 VENTILATION: No special precautions are recom- Absorb remaining material or small spills with an inert * - Hazardous chemical under the criteria of the mended. material and then place in a chemical waste container. OSHA Hazard Communication Standard (29 CFR AIRBORNE EXPOSURE LIMITS: Flush residual spill area with water. 1910.1200). See Section 8 for exposure limits. Large spills that soak into the ground should be dug up, placed in metal drums and disposed of in accordance PRODUCT/COMPONENT OSHA PEL ACGIH TLV with instructions provided under DISPOSAL, Section 3. HAZARDS IDENTIFICATION ® 13 of this MSDS. Contact appropriate state agency ROUNDUP ORIGINAL Not Not established Herbicide established EMERGENCY OVERVIEW when considering a land spreading disposal option. APPEARANCE AND ODOR: Clear, viscous amber- Ethoxylated Tallowamine Not Not established Leaking containers should be separated from non- established colored solution leakers and either the container or its contents trans- 9. PHYSICAL AND CHEMICAL PROPERTIES WARNING STATEMENTS: ferred to a drum or other non-leaking container and Keep out of reach of children. disposed of in accordance with instructions provided Appearance: clear, viscous amber-colored solution WARNING! AVISO! under DISPOSAL, Section 13 of this MSDS. Any re- Odor: practically odorless to slight amine-like odor Si usted no entiende la etiqueta, busque a alguien para covered spilled liquid should be similarly collected and pH: 4.7 (1% solution) que se la explique a usted en detalle. (If you do not disposed of. Specific Gravity: 1.17 @ 25/25 degrees C understand the label, find someone to explain it to you NOTE: These physical data are typical values based in detail.) 7. HANDLING AND STORAGE on material tested but may vary from sample to sample. CAUSES SUBSTANTIAL BUT TEMPORARY EYE IN- Typical values should not be construed as a guaran- JURY HANDLING: Do not get in eyes or on clothing. Avoid teed analysis of any specific lot or as specifications for HARMFUL IF SWALLOWED OR INHALED breathing vapor or spray mist. Wash hands before eat- the product. REFORMULATION IS PROHIBITED ing, drinking, chewing gum, using tobacco, or using the SEE INDIVIDUAL CONTAINER LABEL FOR toilet. Remove clothing immediately if pesticide gets in- 10. STABILITY AND REACTIVITY REPACKAGING LIMITATIONS side. Then wash thoroughly and put on clean clothing. STABILITY: Product is stable under normal conditions POTENTIAL HEALTH EFFECTS Do not apply directly to water, to areas where surface of storage and handling. Store in a cool, well-ventilated LIKELY ROUTES OF EXPOSURE: Skin contact and water is present or to intertidal areas below the mean place away from foodstuffs, reducing agents and acids. inhalation high water mark. Do not contaminate water when dis- MATERIALS TO AVOID: Acids and bases. ® EYE CONTACT: ROUNDUP ORIGINAL Herbicide posing of equipment washwaters. Emptied container HAZARDOUS DECOMPOSITION PRODUCTS: None may cause pain, redness and tearing based on toxicity retains vapor and product residue. Observe all labeled HAZARDOUS POLYMERIZATION: Does not occur. studies. safeguards until container is cleaned, reconditioned, or This product can react with caustic (basic) materials to ® SKIN CONTACT: ROUNDUP ORIGINAL Herbicide destroyed. DO NOT REUSE THIS CONTAINER. liberate heat. This is not a polymerization but rather a is no more than slightly toxic and no more than slightly Spray solutions of this product should be mixed, stored chemical neutralization in an acid base reaction. irritating based on toxicity studies. or applied using only stainless steel, aluminum, fiber- INGESTION: ROUNDUP® ORIGINAL herbicide is no glass, plastic or plastic-lined containers. 11. TOXICOLOGICAL INFORMATION more than slightly toxic based on toxicity studies. No DO NOT MIX, STORE OR APPLY THIS PRODUCT Data from laboratory studies conducted by Monsanto significant adverse health effects are expected to de- OR SPRAY SOLUTIONS OF THIS PRODUCT with ROUNDUP® ORIGINAL Herbicide are summa- velop if only small amounts (less than a mouthful) are IN GALVANIZED OR UNLINED STEEL (EXCEPT rized below: swallowed. Ingestion of similar formulations has been STAINLESS STEEL) CONTAINERS OR SPRAY Single exposure (acute) studies indicate: reported to produce gastrointestinal discomfort with ir- TANKS. This product or spray solutions of this product Oral - Practically Non-toxic (Rat LD50, >5,000 mg/Kg); ritation of the mouth, nausea, vomiting and diarrhea. react with such containers and tanks to produce FIFRA Category IV Oral ingestion of large quantities of one similar product hydrogen gas that may form a highly combustible Dermal - Practically Non-toxic (Rabbit LD50, >5,000 has been reported to result in hypotension and lung gas mixture. This gas mixture could flash or explode, mg/Kg); FIFRA Category IV edema. causing serious personal injury, if ignited by open Inhalation - Slightly toxic (Rat 4-hr LC50, - 2.6 mg/L); INHALATION: ROUNDUP® ORIGINAL Herbicide is flame, spark, welder’s torch, lighted cigarette or other FIFRA Category III no more than slightly toxic if inhaled based on toxicity ignition source. Eye Irritation - Rabbits (6); 24-hr exp.; Slight to Mod- studies. STORAGE: Product is stable under normal conditions erate Irritation, Eye irritation was evident at day 14 but MEDICAL CONDITIONS AGGRAVATED BY EXPO- of storage and handling for at least 5 years. Store cleared by day 21 after exposure in 1 animal; FIFRA SURE: None known. in a cool, well-ventilated place away from foodstuffs, Category II; EC: Corneal Opacity - 0.0, Iris - 0.0, Ery- Refer to Section 11 for toxicological information. reducing agents and acids. thema - 1.7, Chemosis - 0.8 MATERIAL SAFETY DATA SHEET. Database and format copyright © 1998 by C&P Press. All rights reserved. 2

Skin Irritation - Rabbits (6); 4-hr exp.; Essentially Non- irritating; Slight erythema (redness) clearing in all an- 13. DISPOSAL CONSIDERATIONS imals within 24 hours; FIFRA Category IV; EC: Ery- Wastes resulting from the use of this product that can- thema - 0.0, Edema-0.0 not be used or chemically reprocessed should be dis- No skin allergy was observed in guinea pigs following posed of in a landfill approved for pesticide disposal or repeated skin exposure. in accordance with applicable Federal, state or local COMPONENTS procedures. Data from laboratory studies conducted by Monsanto Emptied container retains vapor and product residue. and from the scientific literature on components of ® Observe all labeled safeguards until container is ROUNDUP ORIGINAL Herbicide: cleaned, reconditioned or destroyed. DO NOT CUT Isopropylamine Salt of Glyphosate OR WELD ON OR NEAR THIS CONTAINER. Data from studies with a formulation comprised of 62% Metal Drums: Triple rinse container. Then offer for isopropylamine salt of glyphosate (MON 0139) indicate recycling or reconditioning, or puncture and dispose of the following: in a sanitary landfill, or by other procedures approved In repeat dosing studies (6-month), dogs fed MON by state and local authorities. 0139 exhibited slight body weight changes. Following Metal Bulk: Triple rinse emptied bulk containers. Then repeated skin exposure (3-week) to MON 0139, skin offer for recycling or reconditioning or disposal in a irritation was the primary effect in rabbits. manner approved by state and local authorities. Additional toxicity information is available on Plastic Drums and mini bulk: Do not reuse container. glyphosate, the active herbicidal ingredient of Return container per the Monsanto container return MON 0139. Following repeated exposures (90-days) program. to glyphosate in their feed, decreased weight gains If not returned, triple rinse container, then puncture and were noted at the highest test level in mice, while no dispose of in a sanitary landfill, or by incineration, or, treatment-related effects occurred in rats. Following if allowed, by state and local authorities, by burning. If repeated skin exposure (3 weeks) to glyphosate, burned, stay out of smoke. slight skin irritation was the primary effect observed in rabbits. No skin allergy was observed in guinea 14. TRANSPORT INFORMATION pigs following repeated skin exposure. There was no Follow the precautions indicated in the Handling and evidence of effects on the nervous system, including Storage Section, Section 7 of this MSDS. delayed effects in chickens (repeat oral doses) or DOT Proper Shipping Name: Not Applicable cholinesterase inhibition in rats (single oral doses). DOT Hazard Class/I.D. No.: Not Applicable Reduced body weight gain and effects on liver tissues DOT Label: Not Applicable were observed with long-term (2-year) feeding of U.S. Surface Freight Classification: Weed killing glyphosate to mice at high-dose levels. Reduced compound, N.O.I.B.N. body weight gain and eye changes were observed at the high-dose level in one long-term (2 year) feeding 15. REGULATORY INFORMATION study with rats, while no treatment-related effects SARA Hazard Notification: occurred in a second study. No adverse effects were Hazard Categories Under Criteria of SARA Title III observed in feeding studies with dogs. Glyphosate did Rules (40 CFR Part 370): Immediate not produce tumors in any of these studies. Based Section 313 Toxic Chemical(s): Not Applicable on the results from the chronic studies, EPA has Reportable Quantity (RQ) under U.S. CERCLA: Not classified glyphosate in category E (evidence of Applicable non-carcinogenicity for humans). No birth defects TSCA Inventory: All components are on the US EPA’s were noted in rats and rabbits given glyphosate orally TSCA Inventory List during pregnancy, even at amounts which produced adverse effects on the mothers. Glyphosate was 16. OTHER INFORMATION fed continuously to rats at very high dose levels REASON FOR REVISION: New for 2 successive generations. Toxicity was reported Supersedes MSDS dated: New in offspring from the high dose, a level which also ROUNDUP® is a registered trademark of Monsanto produced adverse effects on the mothers. In a 3 Company generation study conducted at lower dose levels, no This Material Safety Data Sheet (MSDS) serves dif- effects were seen on the ability of male or female rats ferent purposes than and DOES NOT REPLACE OR to reproduce. Glyphosate has produced no genetic MODIFY THE EPA-APPROVED PRODUCT LABEL- changes in a variety of standard tests using animals ING (attached to and accompanying the product con- and animal or bacterial cells. tainer). This MSDS provides important health, safety, Ethoxylated Tallowamine and environmental information for employers, employ- The surfactant component of ROUNDUP® ORIGINAL ees, emergency responders and others handling large Herbicide is reported to cause irritation to the eyes quantities of the product in activities generally other and skin and may contribute to the irritation potential than product use, while the labeling provides that in- reported for this herbicide. Ingestion may produce gas- formation specifically for product use in the ordinary trointestinal irritation, nausea, vomiting and diarrhea. course. Use, storage and disposal of pesticide products are 12. ECOLOGICAL INFORMATION regulated by the EPA under the authority of the Federal ROUNDUP® ORIGINAL Herbicide has been shown Insecticide, Fungicide, and Rodenticide Act (FIFRA) to be slightly to moderately toxic in aquatic studies. through the product labeling, and all necessary and ROUNDUP® ORIGINAL Herbicide has been shown appropriate precautionary, use, storage, and disposal to be practically non-toxic to avian species following information is set forth on that labeling. It is a violation subacute dietary exposure. of federal law to use a pesticide product in any manner not prescribed on the EPA-approved label. Rainbow Trout 22 mg/L Fathead minnow 9.4 mg/L Although the information and recommendations set 96-hr LC50 (static) 96-hr LC50 forth herein (hereinafter ‘‘Information’’) are presented in good faith and believed to be correct as of the date Rainbow Trout 8.2 mg/L Channel catfish 16 mg/L hereof, Monsanto Company makes no representations 96-hr LC50 (dynamic) 96-hr LC50 as to the completeness or accuracy thereof. Informa- Daphnia Magna 37 mg/L Chinook Salmon 20 mg/L 48-hr LC (aeration) 96-hr LC tion is supplied upon the condition that the persons 50 50 receiving same will make their own determination as to Daphnia Magna 24 mg/L Coho Salmon 22 mg/L its suitability for their purposes prior to use. In no event 48-hr LC50 (without 96-hr LC50 aeration) will Monsanto Company be responsible for damages of any nature whatsoever resulting from the use of or Bluegill Sunfish 5.8 mg/L Algae S. 2.1 mg/L reliance upon Information. NO REPRESENTATIONS 96-hr LC50 (dynamic) Capricornutum 72-hr EC OR WARRANTIES, EITHER EXPRESS OR IMPLIED, 50 OF MERCHANTABILITY, FITNESS FOR A PARTIC- Bluegill Sunfish 14 mg/L Bobwhite Quail > 6300 ULAR PURPOSE OR OF ANY OTHER NATURE ARE 96-hr LC50 (static) 8-day LC50 ppm MADE HEREUNDER WITH RESPECT TO INFORMA- Gammarus 42 mg/L Mallard Duck >6300 TION OR THE PRODUCT TO WHICH INFORMATION pseudolimnaeus 8-day LC50: ppm REFERS. 48-hr EC50 ROUNDUPORIGINAL.n97.doc