Chapter 3 Basic Biomechanical Factors & Concepts
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Motion Projectile Motion,And Straight Linemotion, Differences Between the Similaritiesand 2 CHAPTER 2 Acceleration Make Thefollowing As Youreadthe ●
026_039_Ch02_RE_896315.qxd 3/23/10 5:08 PM Page 36 User-040 113:GO00492:GPS_Reading_Essentials_SE%0:XXXXXXXXXXXXX_SE:Application_File chapter 2 Motion section ●3 Acceleration What You’ll Learn Before You Read ■ how acceleration, time, and velocity are related Describe what happens to the speed of a bicycle as it goes ■ the different ways an uphill and downhill. object can accelerate ■ how to calculate acceleration ■ the similarities and differences between straight line motion, projectile motion, and circular motion Read to Learn Study Coach Outlining As you read the Velocity and Acceleration section, make an outline of the important information in A car sitting at a stoplight is not moving. When the light each paragraph. turns green, the driver presses the gas pedal and the car starts moving. The car moves faster and faster. Speed is the rate of change of position. Acceleration is the rate of change of velocity. When the velocity of an object changes, the object is accelerating. Remember that velocity is a measure that includes both speed and direction. Because of this, a change in velocity can be either a change in how fast something is moving or a change in the direction it is moving. Acceleration means that an object changes it speed, its direction, or both. How are speeding up and slowing down described? ●D Construct a Venn When you think of something accelerating, you probably Diagram Make the following trifold Foldable to compare and think of it as speeding up. But an object that is slowing down contrast the characteristics of is also accelerating. Remember that acceleration is a change in acceleration, speed, and velocity. -
Frames of Reference
Galilean Relativity 1 m/s 3 m/s Q. What is the women velocity? A. With respect to whom? Frames of Reference: A frame of reference is a set of coordinates (for example x, y & z axes) with respect to whom any physical quantity can be determined. Inertial Frames of Reference: - The inertia of a body is the resistance of changing its state of motion. - Uniformly moving reference frames (e.g. those considered at 'rest' or moving with constant velocity in a straight line) are called inertial reference frames. - Special relativity deals only with physics viewed from inertial reference frames. - If we can neglect the effect of the earth’s rotations, a frame of reference fixed in the earth is an inertial reference frame. Galilean Coordinate Transformations: For simplicity: - Let coordinates in both references equal at (t = 0 ). - Use Cartesian coordinate systems. t1 = t2 = 0 t1 = t2 At ( t1 = t2 ) Galilean Coordinate Transformations are: x2= x 1 − vt 1 x1= x 2+ vt 2 or y2= y 1 y1= y 2 z2= z 1 z1= z 2 Recall v is constant, differentiation of above equations gives Galilean velocity Transformations: dx dx dx dx 2 =1 − v 1 =2 − v dt 2 dt 1 dt 1 dt 2 dy dy dy dy 2 = 1 1 = 2 dt dt dt dt 2 1 1 2 dz dz dz dz 2 = 1 1 = 2 and dt2 dt 1 dt 1 dt 2 or v x1= v x 2 + v v x2 =v x1 − v and Similarly, Galilean acceleration Transformations: a2= a 1 Physics before Relativity Classical physics was developed between about 1650 and 1900 based on: * Idealized mechanical models that can be subjected to mathematical analysis and tested against observation. -
Modeling the Physics of RRAM Defects
Modeling the physics of RRAM defects A model simulating RRAM defects on a macroscopic physical level T. Hol Modeling the physics of RRAM defects A model simulating RRAM defects on a macroscopic physical level by T. Hol to obtain the degree of Master of Science at the Delft University of Technology, to be defended publicly on Friday August 28, 2020 at 13:00. Student number: 4295528 Project duration: September 1, 2019 – August 28, 2020 Thesis committee: Prof. dr. ir. S. Hamdioui TU Delft, supervisor Dr. Ir. R. Ishihara TU Delft Dr. Ir. S. Vollebregt TU Delft Dr. Ir. M. Taouil TU Delft Ir. M. Fieback TU Delft, supervisor An electronic version of this thesis is available at https://repository.tudelft.nl/. Abstract Resistive RAM, or RRAM, is one of the emerging non-volatile memory (NVM) technologies, which could be used in the near future to fill the gap in the memory hierarchy between dynamic RAM (DRAM) and Flash, or even completely replace Flash. RRAM operates faster than Flash, but is still non-volatile, which enables it to be used in a dense 3D NVM array. It is also a suitable candidate for computation-in-memory, neuromorphic computing and reconfigurable computing. However, the show stopping problem of RRAM is that it suffers from unique defects, which is the reason why RRAM is still not widely commercially adopted. These defects differ from those that appear in CMOS technology, due to the arbitrary nature of the forming process. They can not be detected by conventional tests and cause defective devices to go unnoticed. -
Effects of Alcoholism and Alcoholic Detoxication on the Repair and Biomechanics of Bone
EFEITOS DO ALCOOLISMO E DA DESINTOXICAÇÃO ALCOÓLICA SOBRE O REPARO E BIOMECÂNICA ÓSSEA EFFECTS OF ALCOHOLISM AND ALCOHOLIC DETOXICATION ON THE REPAIR AND BIOMECHANICS OF BONE RENATO DE OLIVEIRA HORvaTH1, THIAGO DONIZETH DA SILva1, JAMIL CALIL NETO1, WILSON ROMERO NAKAGAKI2, JOSÉ ANTONIO DIAS GARCIA1, EVELISE ALINE SOARES1. RESUMO ABSTRACT Objetivo: Avaliar os efeitos do consumo crônico de etanol e da desin- Objective: To evaluate the effects of chronic ethanol consumption toxicação alcoólica sobre a resistência mecânica do osso e neofor- and alcohol detoxication on the mechanical resistance of bone and mação óssea junto a implantes de hidroxiapatita densa (HAD) reali- bone neoformation around dense hydroxyapatite implants (DHA) zados em ratos. Métodos: Foram utilizados 15 ratos divididos em três in rats. Methods: Fifteen rats were separated into three groups: (1) grupos, sendo controle (CT), alcoolista crônico (AC) e desintoxicado control group (CT); (2) chronic alcoholic (CA), and (3) disintoxicated (DE). Após quatro semanas, foi realizada implantação de HAD na (DI). After four weeks, a DHA was implanted in the right tibia of the tíbia e produzida falha no osso parietal, em seguida o grupo AC con- animals, and the CA group continued consuming ethanol, while the tinuaram a consumir etanol e o grupo DE iniciaram a desintoxicação. DI group started detoxication. The solid and liquid feeding of the Ao completar 13 semanas os animais sofreram eutanásia, os ossos animals was recorded, and a new alcohol dilution was effected every foram coletados para o processamento histomorfométrico e os fêmu- 48 hours. After 13 weeks, the animals were euthanized and their res encaminhados ao teste mecânico de resistência. -
Biomechanics (BMCH) 1
Biomechanics (BMCH) 1 BMCH 4640 ORTHOPEDIC BIOMECHANICS (3 credits) BIOMECHANICS (BMCH) Orthopedic Biomechanics focuses on the use of biomechanical principles and scientific methods to address clinical questions that are of particular BMCH 1000 INTRODUCTION TO BIOMECHANICS (3 credits) interest to professionals such as orthopedic surgeons, physical therapists, This is an introductory course in biomechanics that provides a brief history, rehabilitation specialists, and others. (Cross-listed with BMCH 8646). an orientation to the profession, and explores the current trends and Prerequisite(s)/Corequisite(s): BMCH 4630 or department permission. problems and their implications for the discipline. BMCH 4650 NEUROMECHANICS OF HUMAN MOVEMENT (3 credits) Distribution: Social Science General Education course A study of basic principles of neural process as they relate to human BMCH 1100 ETHICS OF SCIENTIFIC RESEARCH (3 credits) voluntary movement. Applications of neural and mechanical principles This course is a survey of the main ethical issues in scientific research. through observations and assessment of movement, from learning to Distribution: Humanities and Fine Arts General Education course performance, as well as development. (Cross-listed with NEUR 4650). Prerequisite(s)/Corequisite(s): BMCH 1000 or PE 2430. BMCH 2200 ANALYTICAL METHODS IN BIOMECHANICS (3 credits) Through this course, students will learn the fundamentals of programming BMCH 4660 CLINICAL IMMERSION FOR RESEARCH AND DESIGN (3 and problem solving for biomechanics with Matlab -
Kinematics, Kinetics, Dynamics, Inertia Kinematics Is a Branch of Classical
Course: PGPathshala-Biophysics Paper 1:Foundations of Bio-Physics Module 22: Kinematics, kinetics, dynamics, inertia Kinematics is a branch of classical mechanics in physics in which one learns about the properties of motion such as position, velocity, acceleration, etc. of bodies or particles without considering the causes or the driving forces behindthem. Since in kinematics, we are interested in study of pure motion only, we generally ignore the dimensions, shapes or sizes of objects under study and hence treat them like point objects. On the other hand, kinetics deals with physics of the states of the system, causes of motion or the driving forces and reactions of the system. In a particular state, namely, the equilibrium state of the system under study, the systems can either be at rest or moving with a time-dependent velocity. The kinetics of the prior, i.e., of a system at rest is studied in statics. Similarly, the kinetics of the later, i.e., of a body moving with a velocity is called dynamics. Introduction Classical mechanics describes the area of physics most familiar to us that of the motion of macroscopic objects, from football to planets and car race to falling from space. NASCAR engineers are great fanatics of this branch of physics because they have to determine performance of cars before races. Geologists use kinematics, a subarea of classical mechanics, to study ‘tectonic-plate’ motion. Even medical researchers require this physics to map the blood flow through a patient when diagnosing partially closed artery. And so on. These are just a few of the examples which are more than enough to tell us about the importance of the science of motion. -
Two-Dimensional Rotational Kinematics Rigid Bodies
Rigid Bodies A rigid body is an extended object in which the Two-Dimensional Rotational distance between any two points in the object is Kinematics constant in time. Springs or human bodies are non-rigid bodies. 8.01 W10D1 Rotation and Translation Recall: Translational Motion of of Rigid Body the Center of Mass Demonstration: Motion of a thrown baton • Total momentum of system of particles sys total pV= m cm • External force and acceleration of center of mass Translational motion: external force of gravity acts on center of mass sys totaldp totaldVcm total FAext==mm = cm Rotational Motion: object rotates about center of dt dt mass 1 Main Idea: Rotation of Rigid Two-Dimensional Rotation Body Torque produces angular acceleration about center of • Fixed axis rotation: mass Disc is rotating about axis τ total = I α passing through the cm cm cm center of the disc and is perpendicular to the I plane of the disc. cm is the moment of inertial about the center of mass • Plane of motion is fixed: α is the angular acceleration about center of mass cm For straight line motion, bicycle wheel rotates about fixed direction and center of mass is translating Rotational Kinematics Fixed Axis Rotation: Angular for Fixed Axis Rotation Velocity Angle variable θ A point like particle undergoing circular motion at a non-constant speed has SI unit: [rad] dθ ω ≡≡ω kkˆˆ (1)An angular velocity vector Angular velocity dt SI unit: −1 ⎣⎡rad⋅ s ⎦⎤ (2) an angular acceleration vector dθ Vector: ω ≡ Component dt dθ ω ≡ magnitude dt ω >+0, direction kˆ direction ω < 0, direction − kˆ 2 Fixed Axis Rotation: Angular Concept Question: Angular Acceleration Speed 2 ˆˆd θ Object A sits at the outer edge (rim) of a merry-go-round, and Angular acceleration: α ≡≡α kk2 object B sits halfway between the rim and the axis of rotation. -
Quantitative Methodologies to Dissect Immune Cell Mechanobiology
cells Review Quantitative Methodologies to Dissect Immune Cell Mechanobiology Veronika Pfannenstill 1 , Aurélien Barbotin 1 , Huw Colin-York 1,* and Marco Fritzsche 1,2,* 1 Kennedy Institute for Rheumatology, University of Oxford, Roosevelt Drive, Oxford OX3 7LF, UK; [email protected] (V.P.); [email protected] (A.B.) 2 Rosalind Franklin Institute, Harwell Campus, Didcot OX11 0FA, UK * Correspondence: [email protected] (H.C.-Y.); [email protected] (M.F.) Abstract: Mechanobiology seeks to understand how cells integrate their biomechanics into their function and behavior. Unravelling the mechanisms underlying these mechanobiological processes is particularly important for immune cells in the context of the dynamic and complex tissue microen- vironment. However, it remains largely unknown how cellular mechanical force generation and mechanical properties are regulated and integrated by immune cells, primarily due to a profound lack of technologies with sufficient sensitivity to quantify immune cell mechanics. In this review, we discuss the biological significance of mechanics for immune cells across length and time scales, and highlight several experimental methodologies for quantifying the mechanics of immune cells. Finally, we discuss the importance of quantifying the appropriate mechanical readout to accelerate insights into the mechanobiology of the immune response. Keywords: mechanobiology; biomechanics; force; immune response; quantitative technology Citation: Pfannenstill, V.; Barbotin, A.; Colin-York, H.; Fritzsche, M. Quantitative Methodologies to Dissect 1. Introduction Immune Cell Mechanobiology. Cells The development of novel quantitative technologies and their application to out- 2021, 10, 851. https://doi.org/ standing scientific problems has often paved the way towards ground-breaking biological 10.3390/cells10040851 findings. -
From Ancient Greece to Byzantium
Proceedings of the European Control Conference 2007 TuA07.4 Kos, Greece, July 2-5, 2007 Technology and Autonomous Mechanisms in the Mediterranean: From Ancient Greece to Byzantium K. P. Valavanis, G. J. Vachtsevanos, P. J. Antsaklis Abstract – The paper aims at presenting each period are then provided followed by technology and automation advances in the accomplishments in automatic control and the ancient Greek World, offering evidence that transition from the ancient Greek world to the Greco- feedback control as a discipline dates back more Roman era and the Byzantium. than twenty five centuries. II. CHRONOLOGICAL MAP OF SCIENCE & TECHNOLOGY I. INTRODUCTION It is worth noting that there was an initial phase of The paper objective is to present historical evidence imported influences in the development of ancient of achievements in science, technology and the Greek technology that reached the Greek states from making of automation in the ancient Greek world until the East (Persia, Babylon and Mesopotamia) and th the era of Byzantium and that the main driving force practiced by the Greeks up until the 6 century B.C. It behind Greek science [16] - [18] has been curiosity and was at the time of Thales of Miletus (circa 585 B.C.), desire for knowledge followed by the study of nature. when a very significant change occurred. A new and When focusing on the discipline of feedback control, exclusively Greek activity began to dominate any James Watt’s Flyball Governor (1769) may be inherited technology, called science. In subsequent considered as one of the earliest feedback control centuries, technology itself became more productive, devices of the modern era. -
Hamilton Description of Plasmas and Other Models of Matter: Structure and Applications I
Hamilton description of plasmas and other models of matter: structure and applications I P. J. Morrison Department of Physics and Institute for Fusion Studies The University of Texas at Austin [email protected] http://www.ph.utexas.edu/ morrison/ ∼ MSRI August 20, 2018 Survey Hamiltonian systems that describe matter: particles, fluids, plasmas, e.g., magnetofluids, kinetic theories, . Hamilton description of plasmas and other models of matter: structure and applications I P. J. Morrison Department of Physics and Institute for Fusion Studies The University of Texas at Austin [email protected] http://www.ph.utexas.edu/ morrison/ ∼ MSRI August 20, 2018 Survey Hamiltonian systems that describe matter: particles, fluids, plasmas, e.g., magnetofluids, kinetic theories, . \Hamiltonian systems .... are the basis of physics." M. Gutzwiller Coarse Outline William Rowan Hamilton (August 4, 1805 - September 2, 1865) I. Today: Finite-dimensional systems. Particles etc. ODEs II. Tomorrow: Infinite-dimensional systems. Hamiltonian field theories. PDEs Why Hamiltonian? Beauty, Teleology, . : Still a good reason! • 20th Century framework for physics: Fluids, Plasmas, etc. too. • Symmetries and Conservation Laws: energy-momentum . • Generality: do one problem do all. • ) Approximation: perturbation theory, averaging, . 1 function. • Stability: built-in principle, Lagrange-Dirichlet, δW ,.... • Beacon: -dim KAM theorem? Krein with Cont. Spec.? • 9 1 Numerical Methods: structure preserving algorithms: • symplectic, conservative, Poisson integrators, -
The Impacts of Technological Invention on Economic Growth – a Review of the Literature Andrew Reamer1 February 28, 2014
THE GEORGE WASHINGTON INSTITUTE OF PUBLIC POLICY The Impacts of Technological Invention on Economic Growth – A Review of the Literature Andrew Reamer1 February 28, 2014 I. Introduction In their recently published book, The Second Machine Age, Erik Brynjolfsson and Andrew McAfee rely on economist Paul Krugman to explain the connection between invention and growth: Paul Krugman speaks for many, if not most, economists when he says, “Productivity isn’t everything, but in the long run it’s almost everything.” Why? Because, he explains, “A country’s ability to improve its standard of living over time depends almost entirely on its ability to raise its output per worker”—in other words, the number of hours of labor it takes to produce everything, from automobiles to zippers, that we produce. Most countries don’t have extensive mineral wealth or oil reserves, and thus can’t get rich by exporting them. So the only viable way for societies to become wealthier—to improve the standard of living available to its people—is for their companies and workers to keep getting more output from the same number of inputs, in other words more goods and services from the same number of people. Innovation is how this productivity growth happens.2 For decades, economists and economic historians have sought to improve their understanding of the role of technological invention in economic growth. As in many fields of inventive endeavor, their efforts required time to develop and mature. In the last five years, these efforts have reached a point where they are generating robust, substantive, and intellectually interesting findings, to the benefit of those interested in promoting growth-enhancing invention in the U.S. -
Chapter 8 Glossary
Technology: Engineering Our World © 2012 Chapter 8: Machines—Glossary friction. A force that acts like a brake on moving objects. gear. A rotating wheel-like object with teeth around its rim used to transmit force to other gears with matching teeth. hydraulics. The study and technology of the characteristics of liquids at rest and in motion. inclined plane. A simple machine in the form of a sloping surface or ramp, used to move a load from one level to another. lever. A simple machine that consists of a bar and fulcrum (pivot point). Levers are used to increase force or decrease the effort needed to move a load. linkage. A system of levers used to transmit motion. lubrication. The application of a smooth or slippery substance between two objects to reduce friction. machine. A device that does some kind of work by changing or transmitting energy. mechanical advantage. In a simple machine, the ability to move a large resistance by applying a small effort. mechanism. A way of changing one kind of effort into another kind of effort. moment. The turning force acting on a lever; effort times the distance of the effort from the fulcrum. pneumatics. The study and technology of the characteristics of gases. power. The rate at which work is done or the rate at which energy is converted from one form to another or transferred from one place to another. pressure. The effort applied to a given area; effort divided by area. pulley. A simple machine in the form of a wheel with a groove around its rim to accept a rope, chain, or belt; it is used to lift heavy objects.