בס"ד BIOMEDICAL ENGINEERING 2013 Scientific Program

(Subject to changes!) 19 – February - 2013 <<>> WWW.ISMBE.ORG.IL Scientific Organizing Committee:

 Prof. Meital Zilberman- University  Dr. Benjamin Gavish- “Yazmonit”Ltd.  Dr. Moshe Brand – Ariel University  Dr. Giora Enden – Ben-Gurion University of the Negev  Dr. Zehava Blechman – Afeka College of Eng.  Prof. Uri Rosenschein – Bnai Zion Medical Center and Technion IIT  Prof. Amir Landesberg - Technion I.I.T.  Prof. Haim Azhari – Technion I.I.T. Contents

Program at a Glance…….3 Detailed Session Lectures…….4

Poster Session Presentations List ……TBD (About 70 posters were submitted)

[1]

בס"ד ISHR Scientific Program

Executive Board:

 Amir Landesberg - Technion -Secretary  Michael Arad - Sheba-Medical Center -Treasurer  Michal Horowitz - The Hebrew University  Ofer Binah - Technion  Ronen Beeri - Hadassah University Hospital

Note: The same admittance ticket enables the participants to attend all lectures (i.e. both ISMBE and ISHR)- provided there is enough room of course.

[2]

בס"ד BIOMEDICAL ENGINEERING & ISHR 2013– Program at a Glance

Time Event Alon Hall Tamar Hall Rimon Hall# 8:30-9:00 ------Gathering Registration and Coffee ------9:00-9:15 Opening session Dean of BME and Dean of Medicine 9:15-9:55 Keynote Lecture 2 Keynote Lecture 1: Prof. Dan Adam Prof. Moshe Shoham Dept. Biomed. Eng. Technion IIT "Plaque vulnerability - Dept. of Mechanical Eng. Technion: Keynote quantification of the "Robots in Medicine" Lectures vascularization within the plaque" Keynote Lecture 3 Prof. Moshe Flugelman Technion- Faculty of Medicine and Carmel Hospital "Cell therapy in cardiovascular medicine" 10:00-11:00 Parallel Sessions -1- -2- I Nano- Blood ISHR-I. Cardiac Biotechnology Vessels Arrhythmias: Needs, research and 11:00-11:05 Coffee Break development 11:05-12:30 Parallel Sessions -3- -4- II Imaging and Tissue Engineering Diagnostics and Drug Delivery 12:30-13:00 Business Meeting For ISMBE members only ISHR members only And Lunch Break Alon Hall Rimon Hall 12:30-13:30 Lunch Break ISHR-II: Rena Yarom Competition And Posters >>> ISMBE Poster Session >>> (oral presentations) 13:30-14:00 Vision Lectures Mayor of Haifa and the Technion President 14:00-14:30 Prof. Rafael Beyar Keynote Lecture 4 Director, Rambam Health Care Campus: "From Today's Challenges to the Hospitals of 2025" 14:30-14:50 Zvi Ladin Ph.D. Keynote Lecture 5 Principal at Boston MedTech Advisors "Latest Developments in FDA Regulations" 14:50-15:50 Parallel Sessions 14:50-16:10 III -5- -6- ISHR-IIIa: Cardiac Matrix Medical Devices Cell Level Research Diseases and Cardiac regeneration 15:50-16:00 Coffee Break 16:00-17:15 Parallel Sessions -8- 16:20-17:50 IV -7- Oral Poster ISHR–IV: BME Industry Presentations Excitation Contractile Session &Announcement of Coupling Competition Winners Heart Failure & Ischemia 17:15-17:45 Open Problems &Announcement of &Hyde Park Competition Winners [3]

בס"ד 17:45-18:00 Concluding Remarks and Farewell

ISMBE 2013- Detailed Lectures Program

Session Speaker and affiliation Title 1 Prof. Shulamit Levenberg Nano-liter droplet devices for parallel single cell Nano- Technion screening and analysis Biotechnology Prof. Ronit Satchi-Fainaro Unraveling the molecular mechanism of tumor Tel-Aviv University dormancy using novel theranosticnanomedicines

Dr. Orit Shefi Nano-Biotechnology for neuroengineering - Bar-Ilan University Studies in-vitro and in-vivo Prof. Noah Lotan Biomaterials: Intelligence at the nanoscale Technion 2 Dr. Iddo Ben-Dov Using 24-hour blood pressure monitoring for the Blood Vessels Hadassah University determination of arterial properties that can Hospital predict death

Dr. Benjamin Gavish How to use gravity for measuring blood vessels Yazmonit Ltd. properties?

Dr. Idit Avrahami Cerebral embolism during cardiopulmonary Ariel University Center bypass - do we have a solution?

Dr. Zehava Blechman Peripheral microcirculation – the end of the Afeka circulation kingdom 3 Dr. Uri Nevo Brain, function and hydrodynamics Imaging and Tel-Aviv University Diagnostics Prof. Dvir Yelin Blood microscope for patient diagnosis Technion Dr. RachelaPopovtzer Molecular imaging of cancer using targeted gold Bar-Ilan University nanoparticles

Prof. Haim Azhari A method for non-invasive remote palpation of Technion tissues using HIFU and MRI Dr. Erez Kestenband Challenges of rapid SW development for the Philips Medical medical industry

[4]

בס"ד 4 Prof. Daniel Cohn Strategies for engineering scaffolds for tissue Tissue Engineering The Hebrew University regeneration and Drug Delivery Prof. Dror Seliktar Tissue engineering hydrogel scaffolds made Technion from protein-polymer conjugates Dr. Giora Enden Mathematical modeling of ultrasound-induced Ben-Gurion University of drug release from liposomes the Negev Prof. Meital Zilberman Active wound healing through drug-eluting Tel-Aviv University novel structures

5 Dr. YanivZigel Analysis of obstructive sleep apnea using audio Medical devices Ben-Gurion University of signals the Negev Prof. Gilad Yossifon On-Chip continuous-flow Technion dielectrophoreticcharacterization and sorting of cells and micro-particles Prof. Josue Sznitman Respiratory physiology using Lab-on-a-Chip Technion devices Nir Ben Evaluation of Nociception Level During General Clinical and Algorithm Anesthesia Manager - Medasense Biometrics Ltd. 6 Prof. Daphne Weihs Cell mechanics and force generation during Cell Level Technion initial stages of metastatic penetration Research Prof. Eitan Kimmel On biological mechano-electric coupling in the Technion form of intra-membrane cavitation, on ultrasound stimulation of neurons and on the ultra-sensitivity of the hearing system

Dr. TomerKalisky Single-cell gene expression in tissues, tumors, Bar-Ilan University and cell lines. Dr. TamirTuller Efficient simulations and engineering of gene Tel-Aviv University expression. 7 Omer Schalit Cohen From an idea to a company – how to build a Biomedical - VP of Business company in the medical devices space Industry Session Development Misgav Venture Accelerator Dr. Amit Goffer Powered exoskeletons: overcoming vertical Founder & President- mobility impairments Argo Medical Technologies Zohar Gendler A substitute bio-artificial pancreas for insulin- CEO- dependent diabetic patients Beta O2 Technologies MarounFarahm Intracranial Neuro Navigation during deep brain Alpha Omega Engineering, stimulation implantation surgeries Nazareth, Israel

[5]

בס"ד Prof. Noemi Bitterman Home Healthcare Devices; A Challenge for Technion Innovation and Enterprise 8 ISMBE Oral 15 Lectures! Poster presentations 9 Coordinated by Dr. Open Problems Benjamin Gavish &Hyde Park Yazmonit Ltd.

ISHR - International Society for Heart Research The Israeli Subsection

- ISHR-I: Dr. BoulosMonther Atrial fibrillation – Unmet needs Cardiac Rambam, Health Care Campus Arrhythmias: Meir Bar-Tal Carto – electrophysiology technology suit Biosense Webster Needs, research and development Dr. EladMaor Cardiovascular application of in vivo 9:45-11:50 Sheba-Medical Center, Tel- electroporation Hashomer Prof. Yoram Etzion Atrial Tachypacing in Conscious Rodents, Uni. Of Gen-Gurion Application for Molecular Research of Human Atrial Fibrillation. Dr. Amit Cohen The MediGuide™ Technology and its MediGuide Navigation Systems, Applications St. Jude Medical

ISHR-II: Orna Avlas et. al. TLR4 expression is associated with cardiac (Edith Hochhauser) dysfunction Rena Yarom Felsenstein Medical Center Competition OshratRaz et. al. The role of TGF-β and the transcription factor 13:00-14:00 (Eli I. Lev) KLF-10 in the function of Early Endothelial Felsenstein Medical Center Progenitor Cells Efrat Kurtzwald-Josefson et. al. Alpha blockade potentiates CPVT therapy in (Michael Arad) calsequestrin-mutant mice Sheba Medical M a k s i n A n n a et.al. Prevention of ischemic damage by over- (Asher Shainberg) expression of Sirtuin6. Bar-Ilan University

ISHR-III: Dr. Izhak Kehat Myocarditis – Open questions Cardiac Matrix Technion Diseases and Cardiac Prof Jonathan Leor Matrix Reloaded regeneration Sheba-Medical Center,

[6]

בס"ד Prof Amir Landesberg The mechanical roles of the Matrix Technion

TomerBronshtein& Marcelle Decellularized ECM: Mechanical, biochemical Machluf and physiological building blocks for cardiac Technion regeneration SimonaBeilin-Nissan Stent Grafts from treating AAA/TAA from Endospan Ltd concept to clinical studies through the animal study phase

ISHR–IVa: Prof. Arie Moran ZnT-1 modulates voltage gated calcium Ben-Gurion University channels and protects cardiomyocytes from Excitation ischemia reperfusion injury Contractile Prof. Ofer Binah Molecular characterization and functional Coupling Technion properties of induced pluripotent stem cells- Heart Failure & derived cardiomyocytes from healthy and Ischemia diseased individuals Dr. Rispler Shmuel Monitoring patients with Heart failure 16:20-17:20 Rambam Health care campus

ISHR–IVb: Darya Pavlov The effect of the sarcomere length on cardiac (amir Landesberg) economy. Excitation Technion Contractile Nahum Buzaglo Critical Role of MAPK Signaling Pathway in Coupling (David Lichtenstein) Cardiac Steroids-Induced Increase in Heart Hebrew University Short Contractility in Zebrafish Presentation InbalRachmin A novel inhibitor of cardiac hypertrophy 17:20-17:45 (Ehud Razin) regulated by MITF Hebrew University Maayan Waldman Ultra low dose of Delta-9-tetrahydrocannabinol (Edith Hochhauser) (THC) administration in-vivo, reduces damage Felsenstein Medical Center of myocardial ischemia

[7]

בס"ד

[8]