What Happens to the Human Body in Space?
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What happens to the human body in space? For over 50 years, NASA’s Human Research Program (HRP) has studied what happens to the human body in space. Researchers are using what they learn to design procedures, devices, and strategies to keep astronauts safe and healthy throughout their missions. NASA engineers use the lessons learned to better design spacecraft and improve the fit and functions of spacesuits. The research also aids in the development and assessment of medical standards, physical fitness programs and standards, physiological and psychological adaptation training, sensorimotor training, and nutritional health protocols. Understanding the effects of spaceflight on humans is essential as astronauts move from the International Space Station in low-Earth orbit to deep space destinations on and around the Moon, and beyond. With the Artemis program, NASA will land the first woman and next man on the Moon using innovative technologies to explore more of the lunar surface than ever before, gathering new data while keeping astronauts healthy and safe. Caption: NASA astronaut Christina Koch pauses as she helps replace equipment on the International Space Station. She and her fellow astronauts face a suite of health effects while in space. Credits: NASA NASA is particularly interested in investigating how the body reacts to long-duration spaceflight as the agency plans for extended missions on the Moon and Mars. Scott Kelly and Christina Koch were the first American astronauts to spend nearly one year in space onboard the space station, twice the previous average. Scott, Christina, and six other astronauts have spent more than 200 days in space during a single spaceflight. In addition to spending almost a year in space, Scott was involved in the unique Twins Study. Scott participated in several biomedical studies onboard the space station while his identical twin brother, retired astronaut Mark Kelly, stayed on Earth as a control subject, someone who provides a basis of comparison. The study provided valuable data about what happened to Scott, physiologically and psychologically, as compared to his brother Mark. Their contribution to science helped generate data that researchers will use for decades to come. NASA is planning more dedicated extended-duration research on the space station. The studies are expected to shed light on how the body adapts to living in the spaceflight environment for various longer time periods, which will be pivotal for future deep space missions. What exactly happens to the body in space and what are the risks? Are the risks the same for astronauts who spend six months on the space station versus those who may be away on a Mars mission for years? The simple answer is “no.” NASA is researching risks for Mars missions which are grouped into five human spaceflight hazards related to the stressors they place on the body. These can be summarized with the acronym “RIDGE,” short for Space Radiation, Isolation and Confinement, Distance from Earth, Gravity fields, and Hostile/Closed Environments. 1. Space Radiation On Earth, we are shielded by the planet’s magnetic field and atmosphere from the majority of particles that make up the space radiation environment. Even so, everyone on Earth is exposed to low levels of radiation every day, from the food we eat to the air we breathe. In space, astronauts are exposed to varied and increased levels of radiation that are different from those on Earth. Three major sources contribute to the space radiation environment: particles trapped in Earth’s magnetic field, solar energetic particles from the Sun, and galactic cosmic rays. A big challenge in reducing the risks of radiation exposure is that some space radiation particles (especially galactic cosmic rays) are difficult to shield against. Exposure to increased radiation can be associated with both short- and long-term health consequences, depending on how much total radiation astronauts experience and the time frame in which they experience that exposure. Increased risk of cancer and degenerative diseases, such as heart disease and cataracts, have been observed in human populations exposed to radiation on Earth. Health risks for astronauts from radiation exposure in space are mainly driven by long-term impacts. Additionally, animal and cellular research indicate that the type of radiation in the space environment has a larger impact on health outcomes compared to the radiation experienced on Earth. Not only will astronauts be exposed to more radiation in space than on Earth, but the radiation they are exposed to could pose increased risks. Caption: Inside the NASA Space Radiation Laboratory, where researchers study the effects of simulated cosmic rays on biological specimens. Credits: NASA The Key: The current strategy to reduce the health risks of space radiation exposure is to implement shielding, radiation monitoring, and specific operational procedures. Compared to typical six-month space station missions, later Moon and Mars missions will be much longer on average. Consequently, the total amount of radiation experienced and associated health risks may increase. NASA is developing new radiation detectors to monitor and characterize the radiation environment, which will provide better estimates of the dose and type of radiation to which the crews are exposed. Scientists and engineers are optimizing and implementing operational procedures that use available vehicle stowage and materials to reduce radiation exposure effectively. To investigate the health risks of space radiation exposure beyond low-Earth orbit, NASA supports research that analyzes the biological effects of simulated cosmic rays at ground- based research facilities. Research at these facilities helps NASA understand and reduce the risk of space radiation, ensure proper measurement of the doses that astronauts receive on the space station and in future spacecraft, and develop advanced materials that improve radiation shielding for future missions. Studies of radiation-exposed human cohorts are also being conducted to estimate the health risks in populations relevant to astronauts. 2. Isolation and Confinement Expedition crews selected for a stay onboard the space station are carefully chosen, trained, and supported to ensure they will be able to work effectively as a team for the duration of their six to 12-month missions. Crews for a Moon or Mars mission will undergo even more careful assessment, selection, and preparation since they will travel farther and potentially for longer than previous humans in an isolated and confined environment, with only a few other people. Additionally, crews will likely be international and multi-cultural, making cross-cultural sensitivity and team dynamics paramount to mission success. Ensuring astronauts get quality sleep is also important; otherwise, their internal biological clocks, or circadian rhythm, might be altered by factors like different dark and light cycles, a small and noisy environment, the stress of prolonged isolation and confinement, and a 37-minute extended day on Mars. It is important to prepare for the fatigue astronauts may experience during spaceflight, given that there will be times with heavy workloads and shifting schedules. To prevent crew boredom, NASA considers the kinds of activities in which the astronauts will participate during a multi-year round trip to Mars. Communication and understanding among crew members are vital to the success of the mission, and changes in morale and motivation are possible as the mission unfolds. This may relate to reduced stimulation, the longing for loved ones, or feeling unable to assist with family emergencies back on Earth, regardless of how long the mission lasts. Using spaceflight analogs on Earth, NASA’s research has revealed that both the duration and type of confined and isolated experience are important to consider. The more restricted the space, and the less contact with people outside the environment, the more likely humans are to develop behavioral or cognitive conditions or psychiatric disorders. Figure Caption: NASA astronaut Christina Koch begins Veg-PONDS-02 experiment on the space station’s vegetable production systems called Veggie. Credits: NASA/David Saint-Jacques The Key: NASA has been studying people in isolated and confined environments for years, and has developed methods and technologies to counteract possible problems. NASA scientists are using devices, such as actigraphy, that help assess and improve sleep and alertness by recording how much people move and how much ambient light is around them. New lighting, spurred by the development of Light-Emitting Diode (LED) technology, is used on the space station to help align astronaut’s circadian rhythms and to improve sleep, alertness, and performance. A 10- minute self-test of vigilance and attention assesses the effect of fatigue on performance. Astronauts write in journals as a safe place to vent frustrations and provide researchers a tool to study behavioral issues that are on the minds of crew members who are living and working in isolation and confinement. Researchers are also looking into using virtual reality to simulate relaxing environments to help improve the mood of crews in isolation. Engaging in relevant, meaningful activities, including learning a language or learning new medical skills, could help ward off depression and boost morale. Crews may even tend to a space garden, which could have positive behavioral health benefits in addition to providing a fresh