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CURRICULUM VITAE JULY 2015

G. RICHARD CURL, M.D., F.A.C.S., RVT

Office Address:

BEVSA 100 High Street Suite A-2 Buffalo, NY 14203 Phone: (716) 859-3301

EDUCATION:

Fellowship Training:

1983 - 1984 Vascular Surgery, Veteran’s Administration Medical Ctr. Boston, Massachusetts

Post Graduate Training:

1977 - 1983 Internship and Residency, General Surgery, Georgetown University Hospital, Washington, DC

Undergraduate Training:

1973 - 1977 M.D., Tufts University Medical School, Boston, Massachusetts

1969 - 1973 University of Pennsylvania, Philadelphia, Pennnsylvania B.A. - Biology

Specialty Training Course:

1997 Endovascular Training Symposium for Vascular Surgeons, SUNY Health Science Center at Brooklyn. New York, NY. January 26 – 31, 1997

Endovascular Surgery Workshop. Society of Vascular Surgery – North American Chapter, International Society for Cardiovascular Surgery. 1997 Joint Annual Meeting. Boston, MA – June 1 – 5, 1997.

1 Specialty Training Courses (cont.)

2000 Meadox Aneurex Endovascular Graft Certification Cleveland, Ohio, June 14 – 16.

Guidant Ancure Endovascular Graft Certification Philadelphia, PA, August 21 – 22.

Certification and Licensure:

10/27/98 – Present New York State License: 176666-1

12/12/84 – Present DEA # AC2971883

1984 – 1985 Diplomat, American Board of Surgery, #30099

1993 – 2005 Diplomat, American Board of Surgery (Recertification)

1988 – 1998 American Board of General Vascular Surgery #734

1996 – 2008 American Board of General Vascular Surgery (Recertification)

1994 Registered Vascular Technologist (RVT)

EMPLOYMENT HISTORY

2007 – Present Vascular Surgeon, Buffalo Endovascular and Vascular Surgical Associates, PLLC – Chairman. Buffalo, New York.

1998 – 2007 Vascular Surgeon, Buffalo Medical Group, Buffalo, New York.

1998 – 2004 Director of Vascular Surgery, Kaleida Health Systems, Buffalo, New York.

2000 – 2002 Director, Noninvasive Vascular Laboratory, Millard Fillmore Suburban Hospital, Williamsville, NY.

1997 – 1998 Acting Chief, Division of Vascular Surgery, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, NY.

2 EMPLOYMENT HISTORY (cont)

1994 – Present Clinical Professor of Surgery, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York.

1995 – Present Consultant in Vascular Surgery, Children’s Hospital of Buffalo, Buffalo, New York.

1995 – Present Consultant in Vascular Surgery, Roswell Park Cancer Institute, Buffalo, New York.

1995 – 2004 Attending in Vascular Surgery, Kenmore Mercy Hospital, Kenmore, New York.

1992 – Present Attending in Vascular Surgery, Buffalo General Hospital, Buffalo, New York.

1988 – Present Attending Surgeon, Buffalo General Hospital, Buffalo, New York.

1992 – Present Attending in Vascular Surgery, Millard Fillmore Hospital, Buffalo, New York.

1992 – 1998 Chief, Vascular Laboratory, Buffalo General Hospital, Buffalo, New York.

1988 – 1998 Attending Surgeon, Erie County Medical Center, Buffalo, New York.

1988 – 1998 Attending Surgeon, Veteran’s Administration Medical Center, Buffalo, New York.

1988 – 1996 Assistant Professor of Surgery, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York.

1986 – 1988 Assistant Professor of Surgery, UMDNJ New Jersey Medical School.

1986 – 1988 Chief, Vascular Surgery Section, East Orange Veteran’s Administration Medical Center, East Orange, New Jersey.

3 1986 – 1988 Staff Surgeon, East Orange Veteran’s Administration Medical Center, East Orange, New Jersey.

1984 – 1985 Associate Investigator, Boston Veteran’s Administration Medical Center, Boston, Massachusetts.

PROFESSIONAL MEMBERSHIPS AND ACTIVITIES

May 9, 1987 – Present Member, Eastern Vascular Society

Oct. 27, 1988 – Present Fellow, American College of Surgeons

1987 - Present Member, American Academy of Surgeons

May 3, 1990 – Present Member, Western New York Vascular Society

June 5, 1990 – Present Member, International Society of Cardiovascular Surgery

Oct. 14,1992- Present Member, Buffalo Surgical Society

Feb. 21,1995-Present Member, International Society of Endovascular Specialists

COMMUNITY, UNIVERSITY, FACULTY, DEPARTMENT SERVICE

National Committees:

1997 – 1998 President, Western New York Vascular Society

1996 – 1997 Vice President, Western New York Vascular Society

1995 – 1996 Chairman, Issues Committee, Eastern Vascular Society

University Service:

1995 – 1998 Institutional Review Board, Medical/Dental Staff Committee, Buffalo General Hospital.

1992 – 1998 Coordinator, Buffalo General Hospital Division III Third-Year Surgery rotation weekly study conference.

1994 – 1998 Co-Director, Division III Service, Buffalo General Hospital

4 University Service (cont)

1991 – 1998 Coordinator, City-Wide Vascular Grand Rounds Weekly topic conference.

1995 – 1996 Curriculum Committee, State University of New York at Buffalo.

1995 – 1996 Faculty Council, State University of New York at Buffalo.

1989 – 1993 Bimonthly lecture on arterial disease for Surgery 700 course.

1989 – 1993 Coordinator, Buffalo Veteran’s Administration Medical Center, Fourth-year surgery rotation weekly study conference.

RESEARCH ACTIVITIES

GRANT SUPPORT

Completed Principal Investigator, “A Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Vasoprost (Alprostadil) in the Treatment of Patients with Severe Intermittent Claudication Due to Peripheral Arterial Occlusion Disease (PAOD)”. Protocol KU-610-004/F-9014, Quintiles, Inc., Cambridge, MA.

Completed Principal Investigator, “A Phase III, Controlled, Multi-Center Randomized, Parallel-Group, Single-Blind Study to Compare the Safety and Hemostatic Efficacy of the Fibrin Sealant, Beriplast® P, with Standard Care of Thrombin-Soaked Gelfoam® in the Treatment of Bleeding Anastomosis Site in Surgical Patients Receiving PTFE Bypass Grafts to the Common Femoral Artery. Protocol B191.201.3/3/2-3001, Centeon LLC, (now Aventis-Behring), King of Prussia, PA.

Completed Principal Investigator, “A Randomized, Double-Blind Placebo and Active-Controlled, Dose Response, Efficacy and Safety Study of Clathrate Extended-Release Capsules (Iloprost) in Patients with Peripheral Arterial Occlusive Disease (PAOD) (Fontaine Stage II). Protocol 107-06, Berlex Laboratories, Montville, New Jersey.

5 Completed Principal Investigator, Post Market Study for Trivascular-Ovation Endograft, 2014-2015.

GRANT SUPPORT (cont.)

Completed Principal Investigator, “A Multi-Center, Double-Blind, Parallel Group Efficacy and Safety Comparison of Ifetroban And Placebo in Patients with Venous Leg Ulcers”. Protocol CV 139-001, Bristol-Myers Squibb Pharmaceutical Research Institute- Conva Tech, Princeton, New Jersey.

Completed Intraarterial Urokinase versus surgery for the treatment of acute lower extremity ischemia, begun April, 1994. $23,000.00.

Completed Investigator, “ derived growth factor and wound healing”. Buffalo Veteran’s Administration Medical Center, Buffalo, New York, $10,000.00.

Completed Co-Investigator, “Iloprost in the healing of arterial ulcers”. Buffalo Veteran’s Administration Medical Center, Buffalo, New York.

Completed Co-Investigator, “Intraoperative Intraarterial Urokinase study”. Buffalo Veteran’s Administration Medical Center, Buffalo, New York, $12,000.00.

Completed Veteran’s Administrative Cooperative Study Number 309, Buffalo Veteran’s Administration Medical Center, Buffalo, New York.

Completed Veteran’s Administrative Cooperative Study Number 362, Buffalo Veteran’s Administration Medical Center, Buffalo, New York.

1987 – 1990 Enhancement of endothelial seeding of prosthetic grafts. Buffalo Veteran’s Administration Medical Center, Buffalo, New York.

1985 – 1987 Veteran’s Administration Regional Advisory Group Grant, $25,000/year.

1984 – 1985 Veteran’s Administration Career Development Award, $34,000/year.

6 PUBLICATIONS

Books/Chapters

1. Curl, GR, Ricotta, JJ: Proximal para-anastomotic aortic aneurysms in critical Problems in vascular surgery. Veith, F (ed), Quality Medical Publishing, Vol. 5, 1993.

2. Curl, GR, Faggioli, GL, Ricotta, JJ: Total excision and extra-anatomic bypass for infected intrarenal aortic grafts in symposium on vascular graft infection. Veith, FJ (ed), Quality Medical Publishing.

3. Curl, GR, Ricotta, JJ: Carotid artery string sign: Differential diagnosis and management. Veith, FJ (ed), Quality Medical Publishing.

4. Curl, GR, Ricotta, JJ: Total prosthetic graft excision and extra-anatomic Bypass. Calligaro, KD, Veith, FJ (eds), Quality Medical Publishing, P 82 -94, 1994.

5. Ramanthan, A, Curl, RG, Harris, L, Two-stage Brachiolbasilic Arteriovenous Fistula for Chronic Haemodialysis Access. ANZ J Surg.2008; March 78 (3): 215 author reply 216.

6. Maru, S, Doslouglu, H, Dryjski, M, Cherr, G, Curl, GR, Harris, L, Thoracic Outlet Syndrome in Children and Young Adults. Eur J Vasc & Endovasc Surg, 2009; 38:560-564.

7. Noor, S, Curl, GR, Meyers, S, RN, Reduction of Surgeries Secondary to Arterial Site Complications: A Single-Center Experience with an Extra- Vascular Closure Device. Vasc & Endovascular Surgery, 5/18/2010.

Articles: Refereed Journals

1. Neefe, J, Curl, GR, Woody, JN: Absolute requirement of adherent cells in the production of adherents cells in the production of human interleukin 2 (IL – 2). Cellular Immunology 63 (1): 71 – 80, 1981.

2. Bush, HL, Nabseth, DC, Curl, GR, O’Hara, ET, Johnson, WC, Vollman, RW: In situ saphenous vein bypass grafts for limb salvage-current fad or viable

7 Alternative to reversed vein bypass grafts. Am. J. Surg. 149:477-480, 1985.

3. Bush, HL, Jakubowski, JA, Curl, GR, Deykin, D: Luminal healing of arterial Endarterectomy: Role of autogenous endolthelial cells. Surg. Forum 36:446, 1986.

4. Bush, HL, Jakubowski, JA, Curl, GR, Deykin, D, Nabseth, DC: The natural History of endothelial structure and function in arterialized vein grafts. J. Vasc. Surg. 3:204-215, 1986.

5. Curl, GR, Jakubowski, JA, Nabseth, DC, Bush, HL: Efficacy of tissue Plasminogen activator and urokinase in a canine model of prosthetic graft . Arch. Surg. 121:782-788, 1986.

6. Curl, GR, Jakubowski, JA, Bush, HL, Deykin, D: Rethrombosis following thrombolytic therapy role of . Circulation 74 (1) 11-21, 1986.

7. Ramanathan,AK, Nader, ND, Dryjski,ML, Dosluoglu, HH, Cherr, GS, Curl, GR, Kuritzky, AS, and Harris, LM: A retrospective review of basilic and cephalic vein-based fistulas. Vascular-Official Journal of the International Society for Vascular Surgery : Vol. 19 No.2, pp 97-104. April, 2011.

8 Articles: Refereed Journals (cont.)

7. Koslow, AR, Farid, D, Curl, GR, Shumko, JZ, Feinberg, RN, Hobson, RW: Protamine induced pulmonary edema in rats. Curr. Surg. 44:219-224, 1987.

8. Bush, HL, Jakubowski, JA, Sentissi, JM, Curl, GR, Hayes, JA, Deykin, D: Neointimal hyperplasia occurring after carotid endarterectomy in a canine model: Effect of endolthelial cell seeding versus perioperative aspirin. J. Vasc. Surg. 5 (1): 18-25, 1987.

9. Curl, GR: Ischemic thrombophlebitis/phlegmasia cerulean dolens and venous Gangrene. Surg. Report 1:32-39, 1990.

10. Faggioli, GI, Curl, GR, Ricotta, JJ: The role of carotid screening prior to coronary artery bypass. J. Vasc. Surg. 12 (6): 724-729, 1990.

11. Ricotta, JJ, Faggioli, GL, Stella, A, Curl, GR, Peer, R, Upson, J, D’Addato, M, Anain, J, Gutierrez, I: Total excision and extra anatomic bypass for aortic graft infection. Am. J. Surg. 162:145-149, 1991.

12. Harris, LM, Faggioli, GL, Fiedler, R, Curl, GR, Ricotta, JJ: Ruptured Abdominal aortic aneurysms: Factors effecting mortality. J.Vasc.Surg. 14:812-820, 1991.

13. Curl, GR, Faggioli, GL, Stella, A, D’Addato, M, Ricotta, JJ: Aneurysm Proximal to an infrarenal aortic graft. J. Vasc. Surg 16 (6): 855-860, 1992.

14. Padberg, FT, Lee, BC, Curl, GR: Hemoaccess site infection. Surg, Gyn. Obst 174:103-108, 1992.

15. Hassett, JM, Luchette, FA, Doerr, RJ, Bernstein, G, Ricotta, JJ, Petrelli, N, Stulc, J, Curl, GR, Booth, FVMcL, Hoover, EL: The utility of an oral examination in a surgical clerkship. Am. J. Surg. 164:372, 1992.

16. Taheri, PA, Bitzer, LG, Curl, GR, Ricotta, JJ, Akers, DL, Hoover, EL: Surgical repair of celiac axis aneurysm and renal oncocytoma: A single case report. Ann. Vasc. Surg. 6:453-455, 1992.

17. Comerota, AIJ, Rao, AK, Throm, RC, Skibinski, CI, Beck, GJ, Ghosh, S, Sun, L, Curl, GR, Ricotta, JJ, Graor, RA, Flynn, WC, Roedersheimer,RL, Alexander, JB: A prospective, randomized, blinded, and placebo-controlled trial of intraoperative intra-arterial urokinase infusion during lower extremity revascularization: Regional and systemic effects. Ann. Surg. 218:534- 543,1993.

9 Articles: Refereed Journals (cont.)

18. Pillai, LK, Gutierrez, IA, Curl, GR, Gage, AM, Balderman, SC, Ricotta, JJ: Evaluation and treatment of carotid stenosis in open-heart surgery patients. J. Surg. Re. 57:312-315, 1994.

19. Harris, LM, Koerner, NA, Curl, GR, Ricotta, JJ: Active pedal plantarflexion A hemodynamic measurement of claudication. J. Vasc. Technology 19 (3): 115-118, 1995.

20. Harris, LM, Peer, R, Curl, GR, Pillai, LK, Upson, JF, Ricotta, JJ: Long- term follow-up of patients with early atherosclerosis. J. Vasc. Surg. 23: 576-581, 1996.

21. Marsan, BU, Curl, GR, Pillai, LK, Gutierrez, IZ, Ricotta, JJ: The thrombosed prosthetic graft is a risk for infection of an adjacent graft. Am. J. Surg. 172 (2): 175-177, 1996.

22. Lee, J, McPhee, M, Loud, P, Curl, GR, Weber, T: Hepatic artery to portal Vein fistula in a cancer patient with new-onset ascites. Surg. Rnds. 20 (2): 47-50, 1996.

23. Harris, LM, Ricotta, JJ, Curl, GR, Booth, FVMcL, Hasset, JM, Leney, G: Screening for asymptomatic deep vein thrombosis in surgical intensive care patients. J. Vasc. Surg. 26 (5): 764-769, 1997.

24. Harris, LM, Armstrong, D, Browne, R, Aljada, R, Peer, RM, Upson, JF, Pillai, LK, Curl, GR, Ricotta, JJ: Premature peripheral vascular disease: Clinical profile and abnormal lipid peroxidation. Cardiovascular Surg. 6 (2): 188-193, 1998.

25. Dosluoglu, HH, Curl, GR, Doerr, RJ, Painton, F, Shenoy, S: Stent-related Iliac artery and iliac vein infections: Two unreported presentations and review of the literature. J. Endovasc. Ther. 8: 202-209, 2001.

CONFERENCES

1. Program Director for the Update on the Diagnosis and Treatment of Venous Thrombosis. Sponsored by the Department of Surgery, School of Medicine and Biomedical Sciences, State University of New York at Buffalo in collaboration with the Western New York Vascular Society. Curl, GR, Campbell, LA, Dryjski, ML, Flynn, WR, Ginsberg, JS, Harris, LM, James, DM, Pillai, LK, Waldman, DL, Buffalo, New York, October 3, 1997.

10 PRESENTATIONS

1. Curl, GR, Jakubowski, JA, Deykin, D, Bush, HL: Elcosanoid production and liminal morphology after carotid endarterectomy: effect of aspirin. Eighteenth Annual Conference on and Cerebrovascular Disease of the American Heart Association, New Orleans, Louisiana, February 7, 1985.

2. Faggioli, GL, Curl, GR, Ricotta, JJ: The role of carotid screening before coronary artery bypass. Annual Meeting of Society of Vascular Surgeons/International Society of Cardiovascular Surgeons, New York, New York, June, 1989.

3. Hasset, JM, Bernstein, GR, Luchette, FA, Doerr, RJ, Ricotta, JJ, Petrelli, N, Sulc, J, Curl, GR, Booth, FVMcL, Hoover, E: The utility of an oral examination In a surgical clerkship. Association for Surgical Education, Portland, Oregon, April 4 – 6, 1991.

4. Harris, LM, Curl, GR, Ricotta, JJ: Optimization of survival after ruptured abdominal aortic aneurysm. Twentieth World Congress of the International Society of Cardiovascular Surgeons, Amsterdam, The Netherlands, September 2, 1991.

5. Curl, GR, Stephan, RN, Gutierrez, IZ, Peer, RM, Ricotta, JJ: Atherosclerotic carotid artery aneurysms. Twentieth World Congress of the International Society of Cardiovascular Surgeons, Amsterdam, The Netherlands, September 2, 1991.

6. Curl, GR, Denk, MR, Jow, W, Ricotta, JJ: Combined surgery for right renal tumor and celiac axis aneurysm. The Seventy-Seventh Clinical Congress of the American College of Surgeons, Chicago, Illinois, October 23, 1991.

7. Ricotta, JJ, Faggioli, GL, Stella, A, Curl, GR, Peer, PM, Upson, JF, D’Addato, M, Anain, J, Gutierrez, IZ: Total excision and extra-anatomic bypass for aortic graft infection. Annual Meeting of the Society for Clinical Vascular Surgery, Kauai, Hawaii, March, 1991.

8. Harris, LM, Faggioli, GL, Fiedler, R, Curl, GR, Ricotta, JJ: Ruptured abdominal Aortic aneurysms: Factors effecting mortality. Annual Meeting of the Eastern Vascular Society, Pittsburgh, Pennsylvania, May, 1991.

9. Hassett, JM, Curl, GR, Bumpers, JL, Luchette, FA, Wolfson, P, Flynn, WR, Hoover, EL: Item format and student performance in objective tests. Association for Surgical Education, Indianapolis, Indiana, April 15-17, 1992.

11 PRESENTATIONS (cont.)

10. Curl, GR, Faggioli, GL, Stella, A, D’Addato, M, Ricotta, JJ: Aneurysmal changes at or above the proximal anastomosis after infrarenal aortic grafting. Annual Meeting of the Eastern Vascular Society, New York, New York, May, 1992.

11. Curl, GR, Pillai, LK, Gutierrez, IZ, Peer, RM, Upson, JF, Ricotta, JJ: The small post-stenotic internal carotid artery-angiographic findings that predict postoperative results. Twenty-First World Congress of the International Society of Cardiovascular Surgeons, Lisbon, Portugal, September, 1993.

12. Pillai, LK, Gutierrez, IZ, Curl, GR, Ricotta, JJ: Evaluation of and treatment of carotid bifurcation lesions in open heart surgery patients. Association of Veteran’s Administration Surgeons, Augusta, Georgia, April 28-May 1, 1993.

13. Curl, GR, Beshlian, KM, VanWylen, DGL, Sciotta, VW, Ricotta, JJ: Microdialysis measurement of skeletal muscle purine metabolite changes in acute venous occlusion. The Sixth Annual Meeting of the American Venous Forum, Maui, Hawaii, February 23, 1994.

14. Curl, GR, Pillai, LK, Raza, ST, Leney, GA, Castilone, A, Ricotta, JJ: Stages vs. combined carotid endarterectomy (CEA) in coronary bypass (CABG) patients. Ninth Annual Meeting Program Eastern Vascular Society, Buffalo, New York, May 6, 1995.

15. Marsan, BU, Curl, GR, Ricotta, JJ: Thrombosed prosthetic graft: a risk for Infection of an adjacent graft. The 24th Annual Symposium on Vascular Surgery, Palm Springs, California, March 20 – 24, 1996.

12