Need and Importance of Conservation of Endangered Tree Oroxylum Indicum (Linn.) Vent
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Therapeutic Potential of Flavonoids in Inflammatory Bowel Disease: a Comprehensive Review
Submit a Manuscript: http://www.f6publishing.com World J Gastroenterol 2017 July 28; 23(28): 5097-5114 DOI: 10.3748/wjg.v23.i28.5097 ISSN 1007-9327 (print) ISSN 2219-2840 (online) REVIEW Therapeutic potential of flavonoids in inflammatory bowel disease: A comprehensive review Ali Salaritabar, Behrad Darvishi, Farzaneh Hadjiakhoondi, Azadeh Manayi, Antoni Sureda, Seyed Fazel Nabavi, Leo R Fitzpatrick, Seyed Mohammad Nabavi, Anupam Bishayee Ali Salaritabar, Behrad Darvishi, Department of Integrative work non-commercially, and license their derivative works on Oncology, Breast Cancer Research Center, Motamed Cancer different terms, provided the original work is properly cited and Institute, ACECR, Tehran 15179-64311, Iran the use is non-commercial. See: http://creativecommons.org/ licenses/by-nc/4.0/ Ali Salaritabar, Behrad Darvishi, Department of Recombinant Protein, Breast Cancer Research Center, Motamed Cancer Manuscript source: Invited manuscript Institute, ACECR, Tehran 15179-64311, Iran Correspondence to: Anupam Bishayee, PhD, Department Farzaneh Hadjiakhoondi, Azadeh Manayi, Medicinal Plants of Pharmaceutical Sciences, College of Pharmacy, Larkin Research Center, Faculty of Pharmacy, Tehran University of University, Miami, FL 33169, Medical Sciences, Tehran 14176-14411, Iran United States. [email protected] Telephone: +1-305-7607511 Antoni Sureda, Research Group on Community Nutrition and Oxidative Stress and CIBEROBN - Physiopathology of Obesity Received: February 16, 2017 and Nutrition, University of Balearic Islands, Palma -
Oroxylum Indicum
Sowjanya K et al /J. Pharm. Sci. & Res. Vol. 11(8), 2019, 2905-2909 Review on Oroxylum Indicum Sowjanya K1, S.swati2, M.manasa3, S. Srilakshmi3, K.mahima3 1 Associate Professor, Department of Pharmaceutical Chemistry, 2 Assistant Professor, Department of Pharmaceutics, 3 Bachelor of Pharmacy, Nirmala College of Pharmacy, Guntur, Andhra Pradesh, India. Abstract: Oroxylum indicum which is also known as midnight horror, “Indian calosanthes” belongs to family bignoneaceae found in Indian subcontinent.Scientific explorations of traditional belief of medicinal properties of Oroxylum indicum have got momentum mostly after the middle 20th century. In the present review, efforts have been made to sum up different aspects of scientific studies on this medicinal plant. It was found that it has great importance in medicinal aspects i.e., possess antimicrobial, antidiabetic, hepato-protective, anti-inflammatory, anti-carcinogenic, immunomodulatory, nephroprotective, anticancer and antimutagenic properties. Keywords: Oroxylum indicum, bignoneaceae, Indian calosanthes. INTRODUCTION: DISTRIBUTION During the past decade, the traditional systems have Oroxylum indicum is native to the Indian subcontinent,in gained importance in the field of medicine. In many the Himalayan foothills with a part extended to Bhutan developing countries, a large proportion of the population and southern China, in Indo-China and the Malaysia relies heavily on traditional practitioners, who are ecozone.It is visible in the forest biome of Manasa dependent on medicinal plants -
Current Perspectives on Medicinal and Aromatic Plants
Review Curr. Pers. MAPs, (2021); 4(1): 66-86 Current Perspectives on Medicinal and Aromatic Plants An International Journal ISSN: 2619-9645 | e-ISSN: 2667-5722 Prevention of Viral Effect and Enhancement of Immune System with the help of Herbal Plants and Himalayan Crude Drugs in SAR-COV-2 Patient: A Review Rishiram BARAL1,2 1Department of Pharmaceutical Sciences, School of Health and Allied Sciences, Faculty of Health Science, Pokhara University, Pokhara, Nepal 2Research Institute of Pharmaceutical Sciences, Department of Pharmacy, Kyungpook National University, Daegu, South Korea *Corresponding author: [email protected] Received : 07/06/2021 https://doi.org/ 10.38093/cupmap.948975 Accepted : 30/06/2021 Abstract After December 2019, Severe Acute Respiratory Syndrome (SAR-COV-2) become a life-threatening issue to the entire human society when it started to spread exponentially all over the world from Wuhan city of China. The virus directly hits the upper and lower respiratory tract of human airways and causes severe damage to the human lung, leading to multiorgan failure, hypoxemia, and dyspnea. Similarly, studies revealed that SAR-COV-2 severely hit the younger and aged population in which the immune system is seriously compromised. The cell of the immune system such as T-cells, B-cells, NK cells, etc. helps to fight against such viral antigen and resist critical viral damage. Therefore, enhancement of the immune system could also be an effective approach to prevent viral infection and even aid in the reduction of the death count. Nowadays, dietary, and herbal remedies are being integrated into the mainstream of the healthcare systems because of their multi-ingredient character, and some of them are known to render efficacy comparable to that of synthetic drug substances. -
Agrosilvopastoral Systems in Northern Thailand and Northern Laos: Minority Peoples’ Knowledge Versus Government Policy
Land 2014, 3, 414-436; doi:10.3390/land3020414 OPEN ACCESS land ISSN 2073-445X www.mdpi.com/journal/land/ Article Agrosilvopastoral Systems in Northern Thailand and Northern Laos: Minority Peoples’ Knowledge versus Government Policy Chalathon Choocharoen 1, Andreas Neef 2,*, Pornchai Preechapanya 3 and Volker Hoffmann 1 1 Institute for Social Sciences of the Agricultural Sector, Rural Communication and Extension (430a), University of Hohenheim, 70593 Stuttgart, Germany; E-Mails: [email protected] (C.C.); [email protected] (V.H.) 2 Center for Development Studies, School of Social Sciences, Faculty of Arts, University of Auckland, Auckland 1142, New Zealand 3 Queen Sirikit Botanic Garden, Mae Rim, Chiang Mai 50180, Thailand; E-Mail: [email protected] * Author to whom correspondence should be addressed; E-Mail: [email protected]; Tel.: +64-9-9233486; Fax: +64-9-3737439. Received: 28 January 2014; in revised form: 2 May 2014 / Accepted: 13 May 2014 / Published: 20 May 2014 Abstract: Traditional agrosilvopastoral systems have been an important component of the farming systems and livelihoods of thousands of ethnic minority people in the uplands of Mainland Southeast Asia. Drawing on a combination of qualitative and participatory inquiries in nine ethnic minority communities, this study emphasizes the complex articulation of local farmers’ knowledge which has been so far excluded from governmental development and conservation policies in the northern uplands of Thailand and Laos. Qualitative analysis of local knowledge systems is performed using the Agroecological Knowledge Toolkit (AKT5) software. Results show that ethnic minorities in the two countries perceive large ruminants to be a highly positive component of local forest agro-ecosystems due to their contribution to nutrient cycling, forest fire control, water retention, and leaf-litter dispersal. -
Germination and Early Growth Status of Threatened Medicinal Tree Species Oroxylum Indicum (Linn.) Vent
Imperial Journal of Interdisciplinary Research (IJIR) Vol-3, Issue-1, 2017 ISSN: 2454-1362, http://www.onlinejournal.in Germination and Early Growth Status of Threatened Medicinal Tree Species Oroxylum indicum (Linn.) Vent. In District Meerut, (U.P.) India Yashwant Rai* & Sudhir Kumar Sharma Assistant Professor, Department of Botany, G.D.C. College Bahal. Haryana, INDIA Assistant Professor Department of Biotechnology, Meerut College Meerut, U.P. INDIA Abstract: Oroxylum indicum is a highly valued resources (Nayar and Sastry, 1987). Clearance of species for the humans, environment and forestry. forest for agriculture, mining, urban and industrial The species is found in some parts of India but now development all contribute to the loss of forests and it is threatened species many areas of the country. tree species in the wild. Management activities Hence, there is an urgent need for conservation of within forests, including burning, logging and this species. The present study was carried out in overgrazing also impact on forest structure, District Meerut for the period August 2016 to functions and processes and can additionally October 2016. The matured, seeds of O.indicum contribute to the loss of tree species. Oroxylum were collected from Botany Department Campus, indicum tree is a native tree often grown as an C.C.S. University Meerut, Uttar Pradesh. A total ornamental for its strange appearance; it was 100 seeds were sown in 5 pots containing soil, distributed throughout the country up to an altitude manure 3:1 ratio. The germination starts three of 1200m and found mainly in ravine and moist days after sowing in the month of August. -
Appendix 1 – Protocol for Preventing Or Reversing Chronic Disease The
Appendix 1 – Protocol for Preventing or Reversing Chronic Disease The first author has developed a protocol over the past decade for preventing or reversing chronic disease based on the following systemic medical principle: “at the present time, removal of cause is a necessary, but not necessarily sufficient, condition for restorative treatment to be effective”[1]. The protocol methodology refines the age-old principles of both reducing harm in addition to providing treatment, and allows better identification of factors that contribute to the disease process (so that they may be eliminated if possible). These contributing factors are expansive and may include a combination of Lifestyle choices (diet, exercise, smoking), iatrogenic and biotoxin exposures, environmental/occupational exposures, and psychosocial stressors. This strategy exploits the existing literature to identify patterns of biologic response using biomarkers from various modalities of diagnostic testing to capture a much broader list of potential contributing factors. Existing inflammatory bowel diseases (IBD) Biomarker Identification to Remove Contributing Factors and Implement Treatment The initial protocol steps are diagnostic. The main output of these diagnostics will be identification of the biomarker levels and symptoms that reflect abnormalities, and the directions of change required to eliminate these abnormalities. In the present study, hundreds of general and specific biomarkers and symptoms were identified from the core IBD literature. The highest frequency (based on numbers of record appearances) biomarkers and symptoms were extracted, and are listed in Table 1 (highest frequency items first, reading down each column before proceeding to the next column). They are not necessarily consensus biomarkers. They are biomarkers whose values were altered by a treatment or contributing factor, and reported in the core IBD literature. -
An Avowal of Importance of Endangered Tree Oroxylum Indicum (Linn.) Vent
Article An avowal of importance of endangered tree Oroxylum indicum (Linn.) Vent. M Gokhale and Y K Bansal* Department of Bioscience, R.D. University, Jabalpur-482 001, Madhya Pradesh, India *Correspondent author Received 2 May 2005; Accepted 5 July 2005 Abstract A small deciduous tree Oroxylum indicum (Linn.) Vent. of family Bignoniaceae, also known as Shivnak, Sonapatha, Shyonaka or Midnight horror possesses economic as well as medicinal importance. The tree was distributed throughout the greater part of India but now it is listed amongst endangered species in many areas in the country. Its conservation is urgently required. Keywords : Shivnak, Sonapatha, Shyonaka, Midnight horror, Oroxylum indicum, Medicinal plant, Endangered tree, Conservation. 7 IPC code; Int. cl. ⎯ A61K 35/78, A01G 23/00 Leaf arrangement on rachis Introduction large (90-180 cm long) and 2-3 pinnate. are numerous, reddish purple outside and Leaflet rachis is very soft and swollen at dull or pale yellow pinkish inside; Deforestation has resulted in a the junction of the branches. Leaflets are arranged in large erect racemes. Fruit is a serious damage to biodiversity and gene in 2-4 pairs, ovate, elliptic or acuminate long woody capsule up to 1m in length, resources1, 2. Naturally grown forests have in shape and glabrous in texture. Flowers containing numerous papery, flat, winged, lost many tree species and Shivnak, light seeds. The fresh root bark is soft and Oroxylum indicum (Linn.) Vent. is juicy and creamish yellow to greyish in one of them. Shivnak grows in India, colour. The taste is sweet initially later Sri Lanka, South China, Celebes, becoming bitter. -
The Biological Activities and Therapeutic Potentials of Baicalein Extracted from Oroxylum Indicum: a Systematic Review
molecules Review The Biological Activities and Therapeutic Potentials of Baicalein Extracted from Oroxylum indicum: A Systematic Review Nik Nur Hakimah Nik Salleh , Farah Amna Othman, Nur Alisa Kamarudin and Suat Cheng Tan * School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia; [email protected] (N.N.H.N.S.); [email protected] (F.A.O.); [email protected] (N.A.K.) * Correspondence: [email protected]; Tel.: +60-9-7677776 Academic Editors: Giuseppe Caruso, Nicolò Musso and Claudia Giuseppina Fresta Received: 1 November 2020; Accepted: 23 November 2020; Published: 2 December 2020 Abstract: In Southeast Asia, traditional medicine has a longestablished history and plays an important role in the health care system. Various traditional medicinal plants have been used to treat diseases since ancient times and much of this traditional knowledge remains preserved today. Oroxylum indicum (beko plant) is one of the medicinal herb plants that is widely distributed throughout Asia. It is a versatile plant and almost every part of the plant is reported to possess a wide range of pharmacological activities. Many of the important bioactivities of this medicinal plant is related to the most abundant bioactive constituent found in this plant—the baicalein. Nonetheless, there is still no systematic review to report and vindicate the biological activities and therapeutic potential of baicalein extracted from O. indicum to treat human diseases. In this review, we aimed to systematically present in vivo and in vitro studies searched from PubMed, ScienceDirect, Scopus and Google Scholar database up to 31 March 2020 based on keywords “Oroxylum indicum” and “baicalein”. -
Ep 3138585 A1
(19) TZZ¥_¥_T (11) EP 3 138 585 A1 (12) EUROPEAN PATENT APPLICATION (43) Date of publication: (51) Int Cl.: 08.03.2017 Bulletin 2017/10 A61L 27/20 (2006.01) A61L 27/54 (2006.01) A61L 27/52 (2006.01) (21) Application number: 16191450.2 (22) Date of filing: 13.01.2011 (84) Designated Contracting States: (72) Inventors: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB • Gousse, Cecile GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO 74230 Dingy Saint Clair (FR) PL PT RO RS SE SI SK SM TR • Lebreton, Pierre Designated Extension States: 74000 Annecy (FR) BA ME •Prost,Nicloas 69440 Mornant (FR) (30) Priority: 13.01.2010 US 687048 26.02.2010 US 714377 (74) Representative: Hoffmann Eitle 30.11.2010 US 956542 Patent- und Rechtsanwälte PartmbB Arabellastraße 30 (62) Document number(s) of the earlier application(s) in 81925 München (DE) accordance with Art. 76 EPC: 15178823.9 / 2 959 923 Remarks: 11709184.3 / 2 523 701 This application was filed on 29-09-2016 as a divisional application to the application mentioned (71) Applicant: Allergan Industrie, SAS under INID code 62. 74370 Pringy (FR) (54) STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES (57) The present specification generally relates to hydrogel compositions and methods of treating a soft tissue condition using such hydrogel compositions. EP 3 138 585 A1 Printed by Jouve, 75001 PARIS (FR) EP 3 138 585 A1 Description CROSS REFERENCE 5 [0001] This patent application is a continuation-in-part of U.S. -
National Register of Medicinal Plants
Digitized by Google Digitized by Google IUCI Nepal National Register of Medicinal Plants IUCl-The World Conservation union May 2000 ... .....,...... , ... 111 IUCN ....,, ., fllrlll •• ... c-.ltloll n.w.wc:-....u.i. IIHI l111I11111I1111II1111II111111111111111 9AZG-Y9Q-23PK Published by: IUCN Nepal Copyright: 2000. IUCN Nepal The role of Swiss Agency for Development and Cooperation in supporting the IUCN Nepal is gratefully acknowledged. The material in this publication may be reproduced in whole or in part and in any form for education or non-profit uses, without special permission from the copyright holder, provided acknowledgment of the source is made. IUCN Nepal would appreciate receiving a copy of any publication which uses this publication as a source. No use of this publication may be made for resale or other commercial purposes without prior written permission of IUCN Nepal. Citation: IUCN Nepal. 2000. National Register ofMedicinal Plants. Kathmandu: IUCN Nepal. ix+ 163 pp. ISBN: 92-9144-048-5 Layout and Design: Upendra Shrestha & Kanhaiya L. Shrestha Cover design: Upendra Shrestha Cover Pictures: Pages from the manuscript of Chandra Nighantu drawn towards the end of 19th century (Courtesy: Singh Durbar Vaidhyakhana Development Committee) Left-hand side: Rajbriksha (Cassia fistula) occuring in the Tarai and other tropical regions of Nepal lying below 1,000 m altitude. Right-hand side: jatamansi (Nardostachys grandif/ora) occuring at 3,000m to 4,000m in the alpine and subalpine zone of Nepal Himalaya. Available from: IUCN Nepal P.O. Box 3923 Kathmandu, Nepal The views expressed in this document are those of the authors and do not necessarily reflect the official views of IUCN Nepal. -
Pharmacokinetics of B-Ring Unsubstituted Flavones
pharmaceutics Review Pharmacokinetics of B-Ring Unsubstituted Flavones Robert Ancuceanu 1, Mihaela Dinu 1,*, Cristina Dinu-Pirvu 2, Valentina Anu¸ta 2 and Vlad Negulescu 3 1 Department of Pharmaceutical Botany and Cell Biology, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania 2 Department of Physical Chemistry and Colloidal Chemistry, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 020956 Bucharest 020956, Romania 3 Department of Toxicology, Clinical Pharmacology and Psychopharmacology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania * Correspondence: [email protected]; Tel.: +40-21-318-0746 Received: 3 July 2019; Accepted: 23 July 2019; Published: 1 August 2019 Abstract: B-ring unsubstituted flavones (of which the most widely known are chrysin, baicalein, wogonin, and oroxylin A) are 2-phenylchromen-4-one molecules of which the B-ring is devoid of any hydroxy, methoxy, or other substituent. They may be found naturally in a number of herbal products used for therapeutic purposes, and several have been designed by researchers and obtained in the laboratory. They have generated interest in the scientific community for their potential use in a variety of pathologies, and understanding their pharmacokinetics is important for a grasp of their optimal use. Based on a comprehensive survey of the relevant literature, this paper examines their absorption (with deglycosylation as a preliminary step) and their fate in the body, from metabolism to excretion. Differences among species (inter-individual) and within the same species (intra-individual) variability have been examined based on the available data, and finally, knowledge gaps and directions of future research are discussed. -
Wild Edible Flowering Plants of the Illam Hills (Eastern Nepal) and Their Mode of Use by the Local Community
Korean J. Pl. Taxon. (2010) Vol. 40 No. 1, pp. 74-77 Wild edible flowering plants of the Illam Hills (Eastern Nepal) and their mode of use by the local community. Amal Kumar Ghimeray1,2, Pankaja Sharma2, Bimal Ghimire2, Kabir Lamsal4, Balkrishna Ghimire4 and Dong Ha Cho2,3* 1Mt. Everest college, Bhaktapur, Kathmandu, Nepal. 2School of Bioscience and Biotechnology, Kangwon National University, Chuncheon 200-701, South Korea. 3Institute of Bioscience & Biotechnology, Kangwon National University, Chuncheon 200-701, Korea. 4Trivuwan University, Botany Department, Kathmandu, Nepal. (Received 2 July 2009 : Accepted 2 March 2010) ABSTRACT: The Illam district, situated in the extreme North Eastern part (Latitude 26.58N and 87.58E Lon- gitude) of Nepal, is a hot spot for floral diversity. The study of wild edible plants of this region was an attempt to highlight the types of wild flowering plants found there and mode of use by the people of the Illam hills. In this respect, a survey of natural resources of some of the representative regions of the district was undertaken and more than 74 major varieties of plant species were found to be used frequently by the people of the hills. The rich diversity occurring in Dioscoriaceae, Moraceae, Rosaceae, Myrtaceae, Poaceae, Urticaceae and Arecaceae pro- vided the wild angiospermic species commonly used by the people of the hills. Keywords: Natural resources, wild edible, flowering plants, Illam hills Nepal is endowed with a wide range of agro-ecological zones, summer between the months of May and September. Due to large variations in climatic and physiographic conditions, which this wide array of climatic zones, the district is a hot spot for have resulted in a rich flora (Olsen, 1998).