Identification of New Possible Genes Involved in Trimethylaminuria

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December identify to approach an provide we paper this drastically In patients. these may of of life of quality that the improve exist evaluation options treatment the sim many therapy, no is on there Although urine. the in and measured concentration of trimethylamine analysis gene genetic on FMO3 based reliable tests are diagnostic there Nowadays trimethylamine. (FMO3), 3 th monooxygenase flavin in a by deficiency or microbiota gut to related dysbiosis a by dysfunctional the in ofmetabolism trimethylamine that can caused be rooted is syndrome the of cause The society. psycho in marginalized they being a from the devastating are patients condition, malodorous is this to Due which odor. unpleasant the for trimethylamine responsible compound of the by excretion consequently, and accumulation, the od by “fish characterized disease as inherited an is syndrome” known also Trimethylaminuria, Abstract Phone number: e Rosalia C Italy 2 Medicine,and UniversityPreventive ofMessina, Messina, Italy 1 Sidoti Antonina D’Angelo Rosalia IDENTIFICATION OF NEW POSSIBLE GENES O Department of Vanguard Medicine and Therapies, Biomolecular Strategies and Neuroscience, I.E.ME.S.T., Palermo, Palermo, I.E.ME.S.T., Neuroscience, and Strategies Biomolecular Therapies, and Medicine Vanguard of Department M and Sciences Dental and Biomedical of Department - ORRESPONDAN RIGINAL mail: mail: e essential enzyme for the metabolism of of metabolism the for enzyme essential e

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INVOLVED IN TRIMETHY orphofunctional Images, Division of Medical Biotechnologies Biotechnologies Medical of Division Images, orphofunctional 2283 odor, affected people are often marginalized. marginalized. often are people affected odor, fish the to due andsociety, the uncommonin is reviews, scientific many in reported as condition, pathological This odor. fish urine, rotten unpleasant an through excreted diet sweat, breath, and a is trimethylamine, which of compound excretion the metabolic accumulation and the inherited by characterized an syndrome, is Trimethylaminuria Introduction genes causative Words: Key in the etiopathogenesis involved of the possibly trimethylaminuria. FMO3, to related genes, other marsmn, al o anan relationships, maintain patients to fail embarrassment, The shown. depression, people affect trimethylaminuria,with as statisticalas studies have that disorders conditions behavior anxiety, psychiatric the of repres may impact social This Accepted: 9 Dec Revised: 4 Dec Received:

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