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Using Genomics and Immunity to Infer 1 2 EEID 2021 SPONSORS The conference organizers gratefully acknowledge the generous support provided by the following sponsors: 3 INDEX General Information p 4 Programme at a glance p 7 List of posters (by island) p 9 List of posters (by session) p 19 Keynote abstracts p 28 Poster abstracts (alphabetical) p 37 Full participant list p 306 4 Welcome Thank you for registering to the EEID 2021 virtual meeting. The meeting will take place in a virtual environment. Below you will find all the essential information to participate in the conference The virtual environment Gather.town is a video-calling space that allows conference participants to interact between each other using an avatar that you'll create upon entering the environment. You will also be able to interact with objects (e.g. posters) in the environment. In order to accommodate the 900 participants, we have created a virtual environment consisting of two different islands (each island can hold a maximum of 500 concomitant participants). The islands are called "FROMAGE" and "DESSERT" (since you could not be here, we decided to bring La France to you). 5 The two islands are very similar. They both have a conference centre which is where most of the science will take place. In the conference centre of each island, you will find: - A conference room: this is where you will come to listen to the keynote speakers. There you will find a zoom link to the keynote talks. The conference rooms in both islands will provide the same zoom link so it does not matter in which island you are to listen to the talks. - The poster rooms. There are nine poster rooms each with its own scientific theme. Each island gives access to different poster rooms: o Poster rooms 1 – 4 are located in "FROMAGE island” o Poster rooms 5 – 9 are located in “DESSERT island” - The sponsors room. This is located in "FROMAGE island" In addition to the conference centre, the islands have plenty of open space to interact socially with other participants. To interact with somebody under a palm tree or on the beach, you simply approach your avatar to his/hers and your cameras will automatically turn on to have a chat. There are also dedicated private spaces scattered across the island where you can chat or organise meetings with one or more participants. In particular, you can use the bungalows located on each side of the island for meetings with a small group of people. Entering and moving between islands Your link to enter the virtual environment has been sent to all participants by email. Upon entering the virtual environment, you will be invited to create an avatar. Please use your real name (Name Surname) to facilitate social interactions. You can find the basics about how to create an avatar and move around here. When you enter the virtual space, you will find yourself on the dock of either FROMAGE or DESSERT. To move between the islands, you may use a "portal". On the dock of each island, you will find a boat. This is your portal to the other island!!! There is another portal inside the conference room. Note that the first time you enter the second island you will need to re-enter your name. What can you and your avatar do? You can use emoticones (emotes), raise your hand, find or follow another avatar (the stalker option), ring another 6 avatar to call their attention, share your screen with somebody else, go into ghost mode (if you don't want to be seen) and even dance. A simplified user guide is provided on our website (www.eeidconference2021.org) The virtual environment of the conference will be accessible continuously from Monday the 14th of at 2pm (CET) until Thursday 17th of June at 7:30pm (CET). Conference organizers will be present throughout the conference. If you need to contact us, send us a message through Gather.town or via email (co- [email protected]) Programme & Information for Poster presenters The conference will start each day at 3pm (CET) with 2 keynote speeches. To attend the speeches, take your avatar to the conference room of FROMAGE or DESSERT. The conference rooms in both islands will provide the same zoom link). Once inside the conference room press "x" and you'll see the zoom link. Each day, immediately after the keynote speeches (at around 5 pm CET), there will be a different poster session where 1/4 of the poster presenters will be by their poster so that they can interact with participants. Please see below the list of poster sessions. Posters will have been set up by the organisers in the appropriate poster room beforehand and will be organised alphabetically. All posters and (where available) their teasers will be accessible throughout the conference in the virtual environment. The teasers will also be accessible from the website of the conference. The prizes for the best teasers will be announced at the last day of the conference (Thursday 17 June). Looking forward to meeting your avatar during this unusual EEID conference! The EEID2021 Organising Committee Thierry Boulinier, Nathalie Charbonnel, Alison Duncan, Sylvain Gandon, Ana Rivero, Benjamin Roche, Philippe Roumagnac. The EEID2021 Scientific Committee Jessie Abbate, Christophe Boëte, Hélène Broutin, Remi Choquet, Ramses Djidjoudemasse, Oliver Kaltz, Sébastien Lion, Catherine Moulia, Marie Hélène Oligastro, Franck Prugnolle, Charlotte Tollenaere, Giaccomo Zilio. 7 PROGRAMME AT A GLANCE (ALL TIMES ARE C.E.T.) 8 Monday 14th June *** All times are CET (Paris time) *** 3:00 pm – 3:15 pm Welcome The crazy life of microbes 3:15 pm – 4:00 pm KEYNOTE: Stéphane Blanc How can multipartite viruses be functional and spread? 4:00 pm – 4:45 pm KEYNOTE: Kimberley Seed Fighting with phages: how epidemic Vibrio cholerae defends against viral attack 5:00 pm – 7:00 pm Poster session 5:00 pm – 6:00 pm 'PCI EvolBiol, PCI Ecology and PCI Infections: free alternatives to evaluate, validate (and publish?) articles in ecology and Evolution of Infectious Diseases’. Join PCI founders Drs Thomas Guillemaud and Denis Bourguet at PCI virtual space in the sponsor room Tuesday 15th June Diversity of host resistance to pathogens 3:00 pm – 3:45 pm KEYNOTE: Jean-Benoit Morel Eternal Rice: a case study of sustainable management of plant resistance 3:45 pm – 4:30 pm KEYNOTE: Anne Chevallereau The Benefits of Diversity-generating Bacterial ‘CRISPR-Cas’ Immune Systems are mitigated by Bacteriophage-encoded ‘anti-CRISPR’ 5:00 pm – 7:00 pm Poster session 5:00 pm – 6:00 pm Increasing your publishing success. Royal Society Editors: Helen Eaton, Jess Metcalf & Katrina Lythgoe. To register visit: https://www.eventbrite.co.uk/e/increasing-your-publishing- success-eeid-registration-155931135223 Wednesday 16th June Using genomics and immunity to infer pathogen dynamics 3:00 pm – 3:45 pm KEYNOTE: Katrina Lythgoe Levels of selection in chronic and acute viruses: From HIV to SARS-CoV-2 3:45 pm – 4:30 pm KEYNOTE: Henrik Salje Using pathogen genomes to identify the role of human behaviours in disease spread 5:00 pm – 7:00 pm Poster session Thursday 17th June Disease control: epidemiological, ecological and evolutionary consequences 3:00 pm – 3:45 pm KEYNOTE: Jessica Metcalf Questioning control: evaluating options, estimating impacts, and considering the longer term 3:45 pm – 4:30 pm KEYNOTE: Scott Nuismer Transmissible vaccines : epidemiological and evolutionary perspectives 4:30 pm – 5:00 pm Teaser prizes and final remarks 5:00 pm – 7:00 pm Poster session 9 LIST OF POSTERS (BY ISLAND) 10 � Fromage Island � Poster rooms 1. evolution of hosts and pathogens 2. Ecology and evolution of human diseases 3. ecology and epidemiology of animal and plant diseases 4. epidemiology of zoonoses and disease emergence Poster room 1 Evolution of hosts and pathogens PRESENTATION NAME POSTER TITLE fE DAY Heterogeneity in viral infections increases the rate of deleterious Allman, Brent Monday 14/6 mutation accumulation Bringing more realistic ecology into modelling how spatial structuring Bartlett, Lewis Monday 14/6 constrains virulence evolution. You can have your cake and eat it, too: adaptation to a novel Bono, Lisa host does not cause strong selection when returned to the original Monday 14/6 host Opqua: an epidemiological modeling framework for pathogen Cárdenas, Pablo Monday 14/6 population genetics and evolution Epidemiological and evolutionary consequences of CRISPR-Cas Chabas, Hélène Monday 14/6 reactivity Transmission mode determines contact structure and drives Collier, Melissa Monday 14/6 pathogen characteristics Host specificity and frequency dependent selection as drivers of Combs, Matthew Monday 14/6 strain diversity for the pathogenic microbe, Borrelia burgdorferi Constitutive Immune Expression Disproportionately Affects Mortality Critchlow, Justin Monday 14/6 Rates During Acute Infection Optimal immune specificity at the intersection of host life history and Downie, Alexander Monday 14/6 parasite epidemiology The source of individual heterogeneity shapes infectious disease Elie, Baptiste Monday 14/6 outbreaks Impact of structural variation turnover in the rapid in vitro evolution Fuandila, Nurul Tuesday 15/6 of Cyprinid herpesvirus 3, a large double-stranded DNA virus Coevolution and competition drive the diversification of CRISPR Guillemet, Martin Tuesday 15/6 immunity Host thermal limits in the face of infectious disease: how important Hector, Tobias Tuesday 15/6 are pathogens? Virulence evolution of infectious hematopoietic necrosis virus post- Loeher, Malina Tuesday 15/6 host jump Comparative Genomics of Bee-Loving Fungi Provides Clues to The Maccaro, Jessica Tuesday 15/6 Evolution of Entomopathogenicity in Ascosphaera spp. Host phenology can select for multiple stable parasite virulence MacDonald, Hannelore Tuesday 15/6 strategies Martin, Reese Immune signaling network evolution under selection by parasites Tuesday 15/6 Specific genetic background is required for acquisition of virulence Martínez-Gómez, Daniel Tuesday 15/6 genes in Escherichia coli.
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