Polyclonal Antibody to GPR18 / Nagly Receptor (1St Extracell

OriGene Technologies, Inc. OriGene Technologies GmbH

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SP4733P Polyclonal Antibody to GPR18 / NAGly receptor (1st Extracell. Dom.) - Aff - Purified

Alternate names: G protein-coupled receptor 18, GPCRW, N-arachidonyl glycine receptor Quantity: 50 µg Concentration: 0.5 mg/ml Background: GPR18 is an Orphan-A GPCR with no known ligand. GPR18 has been reported to be expressed at high levels in testis and spleen and at lower levels in other tissues associated with endocrine and immunologic/hematologic functions. ESTs have been isolated from human blood, bone marrow, brain, colon, liver/spleen, lymph, lymph node, testis, and tonsil libraries. Uniprot ID: Q14330 NCBI: NP_001091670.1 GeneID: 2841 Host: Rabbit Immunogen: Synthetic 18 amino acid peptide from 1st extracellular domain of human GPR18 / NAGly receptor Remarks: Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Mouse, Hamster, Panda, Dog, Horse (94%); Rat, Bat, Bovine (89%); Elephant, Rabbit, Pig (83%). BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR174 (44%). Format: State: Liquid Ig fraction Purification: Immunoaffinity chromatography Buffer System: PBS containing 0.09% Sodium azide Applications: Immunohistochemistry on Paraffin Sections: 6 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Specificity: This antibody recognizes 1st extracellular domain of GPR18 / NAGly receptor. Species Reactivity: Tested: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Hamster, Panda, Dog, Horse, Rat, Bat, Bovine, Elephant, Rabbit, Pig Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20170830 1 / 2 SP4733P: Polyclonal Antibody to GPR18 / NAGly receptor (1st Extracell. Dom.) - Aff - Purified

Pictures: Anti-GPR18 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat- induced antigen retrieval.

For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20170830 2 / 2