Artículos Científicos

Total Page:16

File Type:pdf, Size:1020Kb

Artículos Científicos Editor: NOEL GONZÁLEZ GOTERA Número 166 Diseño: Lic. Roberto Chávez y Liuder Machado. Semana 131214 – 181214 Foto: Lic. Belkis Romeu e Instituto Finlay La Habana, Cuba. ARTÍCULOS CIENTÍFICOS Publicaciones incluidas en PubMED durante el período comprendido entre el 8 y el 14 de noviembre de 2014. Con “vaccin*” en título: 300 artículos recuperados. Vacunas meningococo (Neisseria meningitidis) 74. Outbreak of serotype W135 Neisseria meningitidis in central river region of the Gambia between February and June 2012: A hospital-based review of Paediatric cases. Osuorah D, Shah B, Manjang A, Secka E, Ekwochi U, Ebenebe J. Niger J Clin Pract. 2015 January-February;18(1):41-47. doi: 10.4103/1119-3077.146977. PMID: 25511342 [PubMed - as supplied by publisher] Select item 25511252 87. Interchangeability of meningococcal group C conjugate vaccines with different carrier proteins in the United Kingdom infant immunisation schedule. Ladhani SN, Andrews NJ, Waight P, Hallis B, Matheson M, England A, Findlow H, Bai X, Borrow R, Burbidge P, Pearce E, Goldblatt D, Miller E. Vaccine. 2014 Dec 12. pii: S0264-410X(14)01647-8. doi: 10.1016/j.vaccine.2014.12.018. [Epub ahead of print] PMID: 25510388 [PubMed - as supplied by publisher] Select item 25510387 156. Meningococcal carriage among Georgia and Maryland high school students. Harrison LH, Shutt KA, Arnold KE, Stern EJ, Pondo T, Kiehlbauch JA, Myers RA, Hollick RA, Schmink S, Vello M, Stephens DS, Messonnier NE, Mayer L, Clark TA. J Infect Dis. 2014 Dec 11. pii: jiu679. [Epub ahead of print] 1 PMID: 25505298 [PubMed - as supplied by publisher] Select item 25505296 288. Neisseria meningitidis porA , fetA and fHbp gene distribution in Western Australia 2000 to 2011. Boan P, Metasan N, Tempone S, Harnett G, Speers DJ, Keil AD. BMC Infect Dis. 2014 Dec 12;14(1):686. [Epub ahead of print] PMID: 25495685 [PubMed - as supplied by publisher] Free PMC Article Select item 25495670 Vacunas BCG – ONCO BCG (Mycobacterium bovis) 24. Assessment of tuberculosis infection during treatment with biologic agents in a BCG- vaccinated pediatric population. Atikan BY, Cavusoglu C, Dortkardesler M, Sozeri B. Clin Rheumatol. 2014 Dec 18. [Epub ahead of print] PMID: 25515621 [PubMed - as supplied by publisher] Select item 25515616 114. Correction: A New Recombinant BCG Vaccine Induces Specific Th17 and Th1 Effector Cells with Higher Protective Efficacy against Tuberculosis. The PLOS ONE Staff. PLoS One. 2014 Dec 15;9(12):e116033. doi: 10.1371/journal.pone.0116033. eCollection 2014. PMID: 25506920 [PubMed - as supplied by publisher] Free Article Select item 25506837 155. The recombinant BCG ΔureC::hly vaccine targets the AIM2 inflammasome to induce autophagy and inflammation. Saiga H, Nieuwenhuizen N, Gengenbacher M, Koehler AB, Schuerer S, Moura-Alves P, Wagner I, Mollenkopf HJ, Dorhoi A, Kaufmann SH. J Infect Dis. 2014 Dec 11. pii: jiu675. [Epub ahead of print] PMID: 25505299 [PubMed - as supplied by publisher] Select item 25505298 Vacunas neumococo (Streptococcus pneumoniae) 115. Antibody and Plasmablast Response to 13-Valent Pneumococcal Conjugate Vaccine in Chronic Lymphocytic Leukemia Patients - Preliminary Report. 2 Pasiarski M, Rolinski J, Grywalska E, Stelmach-Goldys A, Korona-Glowniak I, Gozdz S, Hus I, Malm A. PLoS One. 2014 Dec 15;9(12):e114966. doi: 10.1371/journal.pone.0114966. eCollection 2014. PMID: 25506837 [PubMed - as supplied by publisher] Free Article Select item 25506706 154. Live-attenuated influenza virus increases pneumococcal translocation and persistence within the middle ear. Mina MJ, Klugman KP, Rosch JW, McCullers JA. J Infect Dis. 2014 Dec 11. pii: jiu804. [Epub ahead of print] PMID: 25505300 [PubMed - as supplied by publisher] Select item 25505299 213. Cost-effectiveness analysis of pneumococcal conjugate vaccines in preventing pneumonia in Peruvian children. Mezones-Holguín E, Bolaños-Díaz R, Fiestas V, Sanabria C, Gutiérrez-Aguado A, Fiestas F, Suárez VJ, Rodriguez-Morales AJ, Hernández AV. J Infect Dev Ctries. 2014 Dec 15;8(12):1552-62. doi: 10.3855/jidc.5855. PMID: 25500653 [PubMed - in process] Free Article Select item 25500599 216. Serotype 19A Bacteremic Pneumococcal Pneumonia After 4 Doses of 13-Valent Conjugate Vaccine: A Review of Pneumococcal Conjugate Vaccine Effectiveness. Iroh Tam PY, Hanisch BR, Forward B. Clin Pediatr (Phila). 2014 Dec 10. pii: 0009922814562550. [Epub ahead of print] No abstract available. PMID: 25500500 [PubMed - as supplied by publisher] Select item 25500316 238. Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine in Adults ≥ 50 Years of Age in Mexico: An Open-Label Trial. Tinoco JC, Juergens C, Ruiz Palacios GM, Vazquez-Narvaez J, Enkerlin-Pauwells HL, Sundaraiyer V, Pathirana S, Kalinina E, Gruber WC, Scott DA, Schmoele-Thoma B. Clin Vaccine Immunol. 2014 Dec 10. pii: CVI.00711-14. [Epub ahead of print] PMID: 25499011 [PubMed - as supplied by publisher] Select item 25499010 279. Effect of pneumococcal conjugate vaccination on nasopharyngeal carriage in children with early onset of acute otitis media - a randomized controlled trial. 3 Gisselsson-Solén M, Henriksson G, Hermansson A, Melhus A. Acta Otolaryngol. 2015 Jan;135(1):7-13. doi: 10.3109/00016489.2014.950326. PMID: 25496176 [PubMed - in process] Select item 25496172 Vacuna tuberculosis (Mycobacterium tuberculosis) 104. Assessment of phagosomes infected with Mycobacterium tuberculosis as a vaccine candidate against tuberculosis. Sharma A, Parihar P, Sharma J. Indian J Exp Biol. 2014 Nov;52(11):1090-7. PMID: 25507702 [PubMed - in process] Select item 25507510 124. TB Vaccines: The (Human) Challenge Ahead. Hokey DA. Mycobact Dis. 2014 Aug;4(4):e128. No abstract available. PMID: 25506513 [PubMed] Free PMC Article Select item 25506472 140. Extensive Genetic Diversity among Clinical Isolates of Mycobacterium tuberculosis in Central Province of Iran. Soleimanpour S, Hamedi Asl D, Tadayon K, Farazi AA, Keshavarz R, Soleymani K, Seddighinia FS, Mosavari N. Tuberc Res Treat. 2014;2014:195287. doi: 10.1155/2014/195287. Epub 2014 Nov 19. PMID: 25505987 [PubMed] Free PMC Article Select item 25505973 217. Vaccines to prevent tuberculosis infection rather than disease: Physiological and immunological aspects. Orme IM. Tuberculosis (Edinb). 2014 Nov 27. pii: S1472-9792(14)20550-6. doi: 10.1016/j.tube.2014.10.008. [Epub ahead of print] Review. PMID: 25500316 [PubMed - as supplied by publisher] Select item 25500308 262. Mycobacterium Tuberculosis Proteome Microarray for Global Studies of Protein Function and Immunogenicity. 4 Deng J, Bi L, Zhou L, Guo SJ, Fleming J, Jiang HW, Zhou Y, Gu J, Zhong Q, Wang ZX, Liu Z, Deng RP, Gao J, Chen T, Li W, Wang JF, Wang X, Li H, Ge F, Zhu G, Zhang HN, Gu J, Wu FL, Zhang Z, Wang D, Hang H, Li Y, Cheng L, He X, Tao SC, Zhang XE. Cell Rep. 2014 Dec 10. pii: S2211-1247(14)00989-9. doi: 10.1016/j.celrep.2014.11.023. [Epub ahead of print] PMID: 25497094 [PubMed - as supplied by publisher] Free Article Select item 25496995 263. Deciphering the role of exosomes in tuberculosis. Kruh-Garcia NA, Wolfe LM, Dobos KM. Tuberculosis (Edinb). 2014 Nov 21. pii: S1472-9792(14)20567-1. doi: 10.1016/j.tube.2014.10.010. [Epub ahead of print] Review. PMID: 25496995 [PubMed - as supplied by publisher] Select item 25496826 273. Could mycobacterial Hsp70-containing fusion protein lead the way to an affordable therapeutic cancer vaccine? Brauns T, Leblanc P, A Gelfand J, Poznanski M. Expert Rev Vaccines. 2014 Dec 13:1-12. [Epub ahead of print] PMID: 25496347 [PubMed - as supplied by publisher] Select item 25496339 289. Quantiferon TB-Gold conversion can predict active tuberculosis development in elderly nursing home residents. Tsou PH, Huang WC, Huang CC, Lin CF, Wu KM, Hsu JY, Shen GH. Geriatr Gerontol Int. 2014 Dec 11. doi: 10.1111/ggi.12416. [Epub ahead of print] PMID: 25495670 [PubMed - as supplied by publisher] Select item 25495603 Vacuna tosferina (Bordetella pertussis) 1. Filamentous hemagglutinin of Bordetella pertussis: a key adhesin with immunomodulatory properties? Romero RV, Osicka R, Sebo P. Future Microbiol. 2014 Oct;9:1339-1360. PMID: 25517899 [PubMed - as supplied by publisher] Select item 25517896 23. A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis. 5 Bernard NJ, Finlay CM, Tannahill GM, Cassidy JP, O'Neill LA, Mills KH. Mucosal Immunol. 2014 Dec 17. doi: 10.1038/mi.2014.125. [Epub ahead of print] PMID: 25515629 [PubMed - as supplied by publisher] Select item 25515621 159. The Bordetella Adenylate Cyclase Toxin RTX Domain is Immunodominant and Elicits Neutralizing Antibodies. Wang X, Maynard JA. J Biol Chem. 2014 Dec 10. pii: jbc.M114.585281. [Epub ahead of print] PMID: 25505186 [PubMed - as supplied by publisher] Free Article Select item 25505140 Adyuvantes 274. Particulate inorganic adjuvants: recent developments and future outlook. Maughan CN, Preston SG, Williams GR. J Pharm Pharmacol. 2014 Dec 10. doi: 10.1111/jphp.12352. [Epub ahead of print] PMID: 25496339 [PubMed - as supplied by publisher] Select item 25496336 Vacunas, otras 1. Filamentous hemagglutinin of Bordetella pertussis: a key adhesin with immunomodulatory properties? Romero RV, Osicka R, Sebo P. Future Microbiol. 2014 Oct;9:1339-1360. PMID: 25517899 [PubMed - as supplied by publisher] Select item 25517896 2. Conference report from International Congress on Infectious Diseases 2014: part 2. McLoughlin H. Future Microbiol. 2014 Oct;9:1299-1301. PMID: 25517896 [PubMed - as supplied by publisher] 6 Select item 25517836 3. Use and records of child health handbook focused on growth and development. Palombo CN, Duarte LS, Fujimori E, Toriyama AT. Rev Esc Enferm USP. 2014 Aug;48(spe):59-66. Epub 2014 Aug 1. Portuguese, English. PMID: 25517836 [PubMed - as supplied by publisher] Free Article Select item 25517733 4. Therapeutic Vaccination with TNF-Kinoid in TNF Antagonist-Resistant Rheumatoid Arthritis: A Phase II Randomized, Controlled Clinical Trial. Durez P, Vandepapeliere P, Miranda P, Toncheva A, Berman A, Kehler T, Mociran E, Fautrel B, Mariette X, Dhellin O, Fanget B, Ouary S, Grouard-Vogel G, Boissier MC.
Recommended publications
  • References for L'affaire Wakefield: Shades Of
    REFERENCES FOR L’AFFAIRE WAKEFIELD: SHADES OF DREYFUS 1 Alpha-1-Antitrypsin, Autism, And Coeliac Disease, John Walker-Smith and Judith Andrews, The Lancet, 1972; cited by Professor Walker-Smith in his autobiography, Enduring Memories, 2012, p. 211-3; Perinatal Measles Infection And Subsequent Crohn’s Disease. Ekbom A, Wakefield AJ, Zack M, Adami HO. Lancet 1994; Detection Of Immunoreactive Antigen, With A Monoclonal Antibody To Measles Virus, In Tissue From A Patient With Crohn's Disease, Hiroyuki Miyamoto, Tomoyuki Tanaka, Noritoshi Kitamoto, Yoshihiro Fukuda, Takashi Shimoyama, Journal of Gastroenterology, 1995 2 Closed Financial Loops, Kevin De Jesus-Morales and Vinay Prasad , The Hastings Center, 2017 3 Of Measles and Flu, Editor’s Choice, Fiona Godlee, October 2006 4 The Tamiflu Trials, Editorial by Elizabeth Loder, David Tovey, and Fiona Godlee, BMJ, 2014 5 The Next MMR – Could We Do Better? Fiona Godlee, Head of BMJ Knowledge, power point presentation, British National Formulary, 2004 6 Reflections on Investigating Wakefield, Brian Deer, BMJ, February 2, 2010 7 Deposition of Jane Smith, BMJ Deputy Editor June 28, 2012, Wakefield vs. BMJ (Texas litigation) BMJ 8523, p. 45-46 8 How The Case Against The MMR Vaccine Was Fixed, BMJ, January 6, 2011; How The Vaccine Crisis Was Meant To Make Money, BMJ, January 11, 2011; The Lancet’s Two Days To Bury Bad News, BMJ, January 18, 2011 9 Wakefield’s Article Linking MMR Vaccine And Autism Was Fraudulent , Editorial by Fiona Godlee, Editor-in-Chief; Jane Smith, Deputy Editor; Harvey Marcovitz, Associate Editor, BMJ, January 5, 2011 10 CNN, Anderson Cooper 360 Degrees, January 5, 2011 92 11 Merck’s MMR is the only one used in the U.S.
    [Show full text]
  • Department of Health & Human Services (HHS) Records Provided To
    Description of document: Department of Health & Human Services (HHS) records provided to Chairman Darrell Issa, House Oversight and Government Reform Committee, concerning the administration of the Freedom of Information Act (FOIA), 2010-2011 Requested: 10-December-2011 Released date: 07-August-2014 Posted date: 12-October-2015 Source of document: FOIA Request Department of Health and Human Services (HHS) Freedom of Information Officer Hubert H. Humphrey Building, Room 729H 200 Independence Avenue, SW Washington, DC, 20201 Fax: 202-690-8320 Email: [email protected] Note: This is one of several files on the same subject for various agencies available on governmentattic.org. See: http://www.governmentattic.org/5docs/chairmanIssa.htm The governmentattic.org web site (“the site”) is noncommercial and free to the public. The site and materials made available on the site, such as this file, are for reference only. The governmentattic.org web site and its principals have made every effort to make this information as complete and as accurate as possible, however, there may be mistakes and omissions, both typographical and in content. The governmentattic.org web site and its principals shall have neither liability nor responsibility to any person or entity with respect to any loss or damage caused, or alleged to have been caused, directly or indirectly, by the information provided on the governmentattic.org web site or in this file. The public records published on the site were obtained from government agencies using proper legal channels. Each document is identified as to the source. Any concerns about the contents of the site should be directed to the agency originating the document in question.
    [Show full text]
  • Increasing Vaccination: Putting Psychological Science Into Action
    PPIXXX10.1177/1529100618760521Brewer et al.Psychology of Vaccination 760521research-article2018 Psychological Science in the Public Interest Increasing Vaccination: Putting 2017, Vol. 18(3) 149 –207 © The Author(s) 2018 Reprints and permissions: Psychological Science Into Action sagepub.com/journalsPermissions.nav DOI:https://doi.org/10.1177/1529100618760521 10.1177/1529100618760521 www.psychologicalscience.org/PSPI Noel T. Brewer1,2, Gretchen B. Chapman3, Alexander J. Rothman4, Julie Leask5,6, and Allison Kempe7,8,9 1Department of Health Behavior, Gillings School of Global Public Health, University of North Carolina; 2Lineberger Comprehensive Cancer Center, University of North Carolina; 3Department of Social and Decision Sciences, Carnegie Mellon University; 4Department of Psychology, University of Minnesota; 5Faculty of Nursing and Midwifery, University of Sydney; 6Faculty of Medicine, University of Sydney; 7Adult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine; 8Department of Pediatrics, University of Colorado Anschutz Medical Campus; and 9Department of Pediatrics, Children’s Hospital Colorado, Aurora, Colorado Summary Vaccination is one of the great achievements of the 20th century, yet persistent public-health problems include inadequate, delayed, and unstable vaccination uptake. Psychology offers three general propositions for understanding and intervening to increase uptake where vaccines are available and affordable. The first proposition is that thoughts and feelings can motivate getting vaccinated. Hundreds of studies have shown that risk beliefs and anticipated regret about infectious disease correlate reliably with getting vaccinated; low confidence in vaccine effectiveness and concern about safety correlate reliably with not getting vaccinated. We were surprised to find that few randomized trials have successfully changed what people think and feel about vaccines, and those few that succeeded were minimally effective in increasing uptake.
    [Show full text]
  • Thermostable, Dissolvable Buccal Film Rotavirus Vaccine Is Highly Effective in Neonatal Gnotobiotic Pig Challenge Model
    Article Thermostable, Dissolvable Buccal Film Rotavirus Vaccine Is Highly Effective in Neonatal Gnotobiotic Pig Challenge Model Casey Hensley 1, Peng Zhou 1, Sofia Schnur 1, Hassan M. Mahsoub 1 , Yu Liang 1, Min-Xuan Wang 2 , Caroline Page 2, Lijuan Yuan 1,* and Victor Bronshtein 2,* 1 Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA; [email protected] (C.H.); [email protected] (P.Z.); [email protected] (S.S.); [email protected] (H.M.M.); [email protected] (Y.L.) 2 Universal Stabilization Technologies, Inc., San Diego, CA 92121, USA; [email protected] (M.-X.W.); [email protected] (C.P.) * Correspondence: [email protected] (L.Y.); [email protected] (V.B.) Abstract: Difficulties related to storage and transport of currently available live oral rotavirus vaccines can have detrimental consequences on the efficacy of the vaccines. Thus, there is a great need for thermostable vaccines that can eliminate the necessity for cold chain storage or reconstitution before administration. In this study, we developed a dissolvable oral polymeric film comprised of a live attenuated thermostable tetravalent rhesus-human reassortant rotavirus vaccine (RRV-TV) powder and antacid (CaCO3). Immunogenicity and protective efficacy of the vaccine after buccal delivery was evaluated in the gnotobiotic pig model of human rotavirus (HRV) infection and diarrhea. Two doses of the vaccine were highly immunogenic and conferred strong protection against virus shedding and diarrhea upon challenge with a high dose of a virulent G1 HRV in gnotobiotic pigs. Those pigs Citation: Hensley, C.; Zhou, P.; vaccinated with the preserved film vaccine had significantly delayed onset of diarrhea; reduced Schnur, S.; Mahsoub, H.M.; Liang, Y.; duration and area under the curve of diarrhea; delayed onset of fecal virus shedding; and reduced Wang, M.-X.; Page, C.; Yuan, L.; Bronshtein, V.
    [Show full text]
  • Childhood Vaccines in Uganda and Zambia: Determinants and Barriers to Effective Coverage
    Childhood Vaccines in Uganda and Zambia: Determinants and Barriers to Effective Coverage David E Vogt Phillips A dissertation Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy University of Washington 2017 Reading Committee: Stephen Lim, Chair Joseph Dieleman Jessica Shearer Program Authorized to Offer Degree: Global Health ©Copyright 2017 David E Vogt Phillips University of Washington Abstract Childhood Vaccines in Uganda and Zambia: Determinants and Barriers to Effective Coverage David E Vogt Phillips Chair of the Supervisory Committee: Professor Stephen Lim, PhD Global Health As a target of the Sustainable Development Goals, improving childhood immunization is a major priority for global health. Despite progress in recent times however, coverage (vaccination) and effective coverage (immunity) remain a challenge in low and middle-income countries (LMICs). Policy makers, public health practitioners and global organizations such as Gavi, the Vaccine Alliance focus much of their efforts on removing the barriers that prevent children from successful immunization. Barriers to effective coverage are complex and difficult to measure though. Extensive research effort has been devoted to understanding them, but most studies and systematic reviews have been limited in bread and depth. As vaccine programs in LMICs continue progress toward effective coverage of immunizations, better understanding of determinants and barriers will be imperative to close remaining gaps and inequities. Policies and programs like Gavi’s health system strengthening support would benefit from a more rigorous examination of the determinants and barriers to immunization. The work presented here represents a small step towards better understanding of why some children remain unvaccinated, and why some vaccines fail to produce immunity.
    [Show full text]
  • Prevention and Control of Influenza
    May 1, 1998 / Vol. 47 / No. RR-6 TM Recommendations and Reports Prevention and Control of Influenza Recommendations of the Advisory Committee on Immunization Practices (ACIP) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention (CDC) Atlanta, Georgia 30333 The MMWR series of publications is published by the Epidemiology Program Office, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, Atlanta, GA 30333. SUGGESTED CITATION Centers for Disease Control and Prevention. Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 1998;47(No. RR-6):[inclusive page numbers]. Centers for Disease Control and Prevention................................ Claire V. Broome, M.D. Acting Director The material in this report was prepared for publication by: National Center for Infectious Diseases.................................. James M. Hughes, M.D. Director Division of Viral and Rickettsial Diseases .................. Brian W.J. Mahy, Ph.D., Sc.D. Director The production of this report as an MMWR serial publication was coordinated in: Epidemiology Program Office............................................Barbara R. Holloway, M.P.H. Acting Director Andrew G. Dean, M.D., M.P.H. Acting Editor, MMWR Series Office of Scientific and Health Communications (proposed) Recommendations and Reports................................... Suzanne M. Hewitt, M.P.A. Managing Editor Valerie R. Johnson Project Editor Morie M. Higgins Visual Information Specialist Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of Health and Human Services. Copies can be purchased from Superintendent of Documents, U.S. Government Printing Office, Washington, DC 20402-9325.
    [Show full text]
  • 2010 Annual Report Vision
    Department of RESEARCH & EVALUATION Advancing Science, Enhancing Lives. Kaiser Permanente Southern California | 2010 Annual Report Vision The Department of Research & Evaluation has an integral role in the success of Kaiser Permanente Southern California by conducting high-quality, innovative translational research that benefits the health of its members and the communities from which they come. Mission The mission of the Department of Research & Evaluation is to initiate and conduct high-quality, public-sector health services, epidemiologic, behavioral and clinical research that has a demonstrable positive impact on the health and well-being of Kaiser Permanente Southern California members and the general population. Advancing Science, Enhancing Lives Table of Contents Director’s Message .................................................................................................................................. 4 Department of Research & Evaluation At-A-Glance ............................................................................. 6 2010 Accomplishments ........................................................................................................................... 7 Grants & Awards ................................................................................................................................. 7 Publications Overview ........................................................................................................................ 9 Research Funding .............................................................................................................................
    [Show full text]
  • Sectarian Identity and the Aim of Integration: Attitudes of American Homeopaths Towards Smallpox Vaccination in the Late Nineteenth Century
    Sectarian Identity and the Aim of Integration: Attitudes of American Homeopaths Towards Smallpox Vaccination in the Late Nineteenth Century Eberhard Wolff Introduction N THE HISTORIOGRAPHY OF MEDICINE, sectarian medical movements have I been analysed mostly from the perspective of a conflict with regular medicine. Homeopathy, in particular, has been regarded as a distinct medical world with a way of therapeutic thinking apart from orthodox medicine and of not being compatible with it.1 On the level of theory, this is largely correct as, especially, the efficiency of minimal doses cannot be accepted by regulars, and 'regular' doses cannot be accepted by homeopaths who take seriously the homeopathic principles. Thus, from this point of view, an integration of homeopathy with allopathy is, to some extent, a contradiction in terms. However, recently this perspective has been replaced partially by focusing on those issues which regular and sectarian physicians had in common.2 In fact, these boundaries between the factions were never so clear.. cut for on the level of homeopathy's everyday practice (or practical principles); transgression was normal. Nevertheless, these transgressions raise the 218 Culture, Knowledge, and Healing question of how thoroughly homeopaths kept to the concept to which they were devoted. An exploration and analysis of these transgressions can throw light on how homeopathic physicians perceived their identity as a group. This paper traces the identity of American homeopathic physicians in the late nineteenth century, but offers a different approach to that of Naomi Rogers by focusing on a single issue. The homeopathic, sectarian or distinctive identity of homeopathic physicians between sectarian segregation on the one hand and eclectic3 integration on the other is studied only as it is reflected in their judgement of smallpox vaccination.
    [Show full text]
  • United States District Court Middle District of Florida Ft
    Case 2:04-cv-00552-VMC-SPC Document 45 Filed 07/08/2005 Page 1 of 37 UNITED STATES DISTRICT COURT MIDDLE DISTRICT OF FLORIDA FT. MYERS DIVISION DR. AND MRS. ROBERT SHARKEY on behalf of RYAN REED SHARKEY, a minor, Plaintiffs, v. Civil Action No. 2:04-CV-552 FOOD AND DRUG ADMINISTRATION, Defendant, and MERCK & CO., INC., Defendant-Intervenor. _____________________________________/ MEMORANDUM IN OPPOSITION TO DEFENDANTS’ MOTIONS FOR SUMMARY JUDGMENT AND IN SUPPORT OF PLAINTIFFS’ MOTION FOR SUMMARY JUDGMENT OR FOR DISCOVERY Plaintiffs brought this action under the Freedom of Information Act (FOIA), 5 U.S.C. § 552, to compel the Food and Drug Administration (FDA) to produce records reflecting the net number of doses in each lot of hepatitis B vaccine distributed in the United States. The FDA has identified 19 documents responsive to plaintiffs’ request but has refused to produce the records on the ground that they contain confidential commercial information subject to withholding under FOIA Exemption 4, 5 U.S.C. § 552(b)(4). The FDA and defendant-intervenor Merck & Co., Inc. (Merck) have filed motions for summary judgment, and plaintiffs have filed a cross- motion for summary judgment or, in the alternative, for discovery. Because defendants have failed to meet their burden of demonstrating that the requested documents are exempt from disclosure, the Court should deny defendants’ motions for summary judgment, grant summary judgment for plaintiffs, and order the FDA to produce the requested records. Case 2:04-cv-00552-VMC-SPC Document 45 Filed 07/08/2005 Page 2 of 37 FACTS There are two recombinant hepatitis B vaccines licensed for use in the United States: Merck’s Recombivax HB and Glaxo’s Engerix-B.1 On March 10, 2003, plaintiffs submitted a FOIA request to the FDA seeking the net number of doses (doses distributed less doses returned) in each lot of recombinant hepatitis B vaccine distributed in the United States.
    [Show full text]
  • The Politics of Vaccination
    SOCIAL HISTORIES OF MEDICINE vaccination of The politics SOCIAL HISTORIES OF MEDICINE In The politics of vaccination scholars from across the globe provide a comparative overview of vaccination policies at different times, in widely different places and under different types of political regime. Contributors analyse vaccination in relation to state power, concepts of national identity and solidarity and of individuals’ obligations to self and others. They explore relationships between vaccination policies and vaccine-making and the discourses and debates on citizenship and nationhood that have often accompanied mass campaigns. The analysis unmasks the idea of vaccination as a simple health technology and makes visible the complexities in which vaccination is embedded. Core themes include vaccination programmes as an element of state formation; citizens’ articulation of seeing (or not seeing) their needs incorporated into public health practice; allegations that development aid has inappropriately steered third-world health policies; and an ideological shift that regards vaccines as marketable and profitable commodities rather than as essential tools of public health. Above all, the essays suggest vaccination is a novel lens through which to view historical changes in ‘society’ and ‘nation’. The politics of vaccination is completed with an afterword by William Muraskin in which, reflecting on his years of work on the history of vaccination, he focuses on the role of a small group of global health leaders. This group launched major disease eradication programmes, prioritising specific types of health care intervention irrespective of their compatibility with the priorities (Eds) Greenough Blume and Holmberg, of individual nations. The collection in its entirety shows how such ‘globalised’ approaches may foster political upheaval and will be of interest to students, researchers and teachers in global health.
    [Show full text]
  • Global Vaccine Hesitancy Segmentation: a Cross-European Approach
    Article Global Vaccine Hesitancy Segmentation: A Cross-European Approach Almudena Recio-Román *, Manuel Recio-Menéndez and María Victoria Román-González Department of Economy and Business, University of Almería, Carretera de Sacramento s/n, 04120 Almería, Spain; [email protected] (M.R.-M.); [email protected] (M.V.R.-G.) * Correspondence: [email protected] Abstract: Vaccine-preventable diseases are global mainly in a globalized world that is characterized by a continuous movement of people and goods across countries. Vaccine hesitancy, the reluctance or refusal to vaccinate despite the availability of vaccines, is rising worldwide. What if the problem of vaccine hesitancy could be most effectively managed when treated globally rather than on a national or regional basis? What if a global vaccine-hesitant segment exists and the differences among countries are not so significant? Based on the Global Marketing Strategy paradigm, this paper shows that seven different cross-European segments exist based on the beliefs, attitudes, and behaviors collected in 28 European countries. These pan-European segments are differentiable (people in those segments have similar characteristics that are visibly dissimilar from the ones in other segments) and actionable (organizations would be able to propose interventions to the hesitant segments based on their profiles). With segmentation being the starting point of many public health intervention strategies for avoiding vaccine-hesitancy, the results recommend moderating the full-adaptation strategy that follows the “context matters” principle suggested by several political and public health international organizations. Embracing a more standardized strategy will allow the development of Citation: Recio-Román, A.; better services and strategies that support and enable desirable vaccination behaviors.
    [Show full text]
  • Neurotoxic Effects of Postnatal Thimerosal Are Mouse Strain
    Molecular Psychiatry (2004) 9, 833–845 & 2004 Nature Publishing Group All rights reserved 1359-4184/04 $30.00 www.nature.com/mp IMMEDIATE COMMUNICATION Neurotoxic effects of postnatal thimerosal are mouse strain dependent M Hornig1, D Chian1 and WI Lipkin1,2 1Jerome L and Dawn Greene Infectious Disease Laboratory, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA; 2Departments of Neurology and Pathology, Columbia University College of Physicians and Surgeons, New York, NY, USA The developing brain is uniquely susceptible to the neurotoxic hazard posed by mercurials. Host differences in maturation, metabolism, nutrition, sex, and autoimmunity influence outcomes. How population-based variability affects the safety of the ethylmercury-containing vaccine preservative, thimerosal, is unknown. Reported increases in the prevalence of autism, a highly heritable neuropsychiatric condition, are intensifying public focus on environmental exposures such as thimerosal. Immune profiles and family history in autism are frequently consistent with autoimmunity. We hypothesized that autoimmune propensity influences outcomes in mice following thimerosal challenges that mimic routine childhood immuniza- tions. Autoimmune disease-sensitive SJL/J mice showed growth delay; reduced locomotion; exaggerated response to novelty; and densely packed, hyperchromic hippocampal neurons with altered glutamate receptors and transporters. Strains resistant to autoimmunity, C57BL/ 6J and BALB/cJ, were not susceptible. These
    [Show full text]