nutrients Article Dietary Patterns Are Differentially Associated with Atypical and Melancholic Subtypes of Depression Aurélie M. Lasserre 1,* , Marie-Pierre F. Strippoli 1 , Pedro Marques-Vidal 2 , Lana J. Williams 3, Felice N. Jacka 3, Caroline L. Vandeleur 1, Peter Vollenweider 2 and Martin Preisig 1 1 Department of Psychiatry, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland;
[email protected] (M.-P.F.S.);
[email protected] (C.L.V.);
[email protected] (M.P.) 2 Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland;
[email protected] (P.M.-V.);
[email protected] (P.V.) 3 Barwon Health, IMPACT—The Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong 3220, Australia;
[email protected] (L.J.W.);
[email protected] (F.N.J.) * Correspondence:
[email protected]; Tel.: +41-21-314-3552 Abstract: Diet has been associated with the risk of depression, whereas different subtypes of depres- sion have been linked with different cardiovascular risk factors (CVRFs). In this study, our aims were to (1) identify dietary patterns with exploratory factor analysis, (2) assess cross-sectional associations between dietary patterns and depression subtypes, and (3) examine the potentially mediating effect of dietary patterns in the associations between CVRFs and depression subtypes. In the first follow-up of the population-based CoLaus|PsyCoLaus study (2009–2013, 3554 participants, 45.6% men, mean age Citation: Lasserre, A.M.; Strippoli, 57.5 years), a food frequency questionnaire assessed dietary intake and a semi-structured interview M.-P.F.; Marques-Vidal, P.; Williams, allowed to characterize major depressive disorder into current or remitted atypical, melancholic, L.J.; Jacka, F.N.; Vandeleur, C.L.; and unspecified subtypes.