300 years of GSK Three centuries of innovation

1 715 1 848 1880 1883 1 891 Plough Court Pharmacy 1 830 Thomas Beecham launches Burroughs Wellcome The Horlick brothers patent the 1 884 Smith, Kline & Company acquires established in London John K Smith and his the Beecham’s Pills business & Company established process of purifying and drying Burroughs Wellcome French, Richards and Company. by Silvanus Bevan, brother-in-law open a drugstore in England. By the early twentieth in London by pharmacists milk with malt, a product that & Company registers The original company that John which later becomes in Philadelphia, which would century, production is at one Henry Wellcome and later becomes known as ‘Tabloid’ as a trademark K Smith founded went through Allen & Hanburys Ltd. later become Smith, million pills per day. Silas Burroughs. Horlicks Malted Milk. to describe its numerous name and ownership Kline & Company. compressed changes before becoming Smith, tablets. Kline & French Company.

1 969 1 944 1936 1906 1 894 Ventolin launched by By mid-1944, 80% of the UK’s Wellcome Trust’s first ‘Glaxo’ trademark Wellcome Physiological Allen & Hanburys as penicillin doses are routed chairman Sir Henry Dale is registered. Research Labs established, 1 972 a treatment for asthma. through Glaxo Laboratories’ wins Nobel Prize in Joseph Nathan & Co. Ltd. focused on biological Medicine. 1 924 Amoxycillin discovered. Greenford site. Sir John Vane Joseph Nathan & Co. realised that selling dried milk experimentation including early forms of vaccines. Scientists at Beecham (1982) and George launches its first as an infant food called for a Research Laboratories Hitchings, Gertrude Elion pharmaceutical product, more appealing name than Defiance, discover amoxycillin and Sir James Black (1988) a vitamin D supplement the name used in 1981 and launch Amoxil, later win the same award. called Ostelin. New Zealand. They started Zovirax launched for viral which will become with Lacto, and by adding and herpes infections, one of an antibiotic staple. changing letters, the name many life-saving drugs rationally Glaxo was born. designed by Hitchings and Elion.

1988 2 000 2 004 Zantac by Glaxo becomes Merger of Glaxo Wellcome and Clinical Trial Register launched. 1 987 the world’s biggest prescription 1995 SmithKline Beecham creates GSK is the first company to A new medicine Retrovir (AZT) Glaxo and Wellcome merge to drug for stomach ulcers. GlaxoSmithKline plc, known launch an online site of clinical by Wellcome becomes the first form Glaxo Wellcome plc., the as GSK. A year later, we acquire trial data accessible to all. approved treatment for AIDs. world’s largest pharmaceutical company. Block Drug Co. adding a wider range of consumer products to 1 989 1998 our portfolio. Merger of SmithKline Beckman SmithKline Beecham and the and the Beecham Group to form World Health Organization join SmithKline Beecham plc. forces to eliminate lymphatic filariasis (elephantiasis) by the year 2020.

2018 2017 2016 2 014 2012 2 009 To support advances in the GSK launches three new Sensodyne becomes 2015 Phase III trial concludes for the GSK is an official supplier to Stiefel acquired and development of new medicines, products: Shingrix, a vaccine GSK’s first consumer brand Major 3-part transaction world’s first malaria vaccine the London 2012 Olympic and ViiV Healthcare launched. GSK embarks on a major research to help prevent shingles in to reach £1bn in sales. with Novartis. candidate, RTS,S. The pilot Paralympic Games, providing 2011 GSK becomes a leader in initiative to sequence genetic people aged 50 or older; GSK and Novartis create joint implementation will begin in official laboratory services for Human Genome Sciences skincare with the acquisition data from 500,000 volunteer triple therapy inhaler Trelegy Consumer Healthcare venture. Ghana, Kenya and Malawi. anti-doping measures. and GSK receive approval of Stiefel. GSK and Pfizer launch participants in the UK Biobank Ellipta, for patients with GSK acquires the Novartis for Benlysta, the first new ViiV Healthcare, a company healthcare resource. COPD; and Juluca, the first global Vaccines business and lupus treatment in focused on delivering advances 2-drug regimen for people divests its marketed Oncology 50 years. in treatment and care for living with HIV. portfolio business to Novartis. HIV communities.