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From the Cover Contents October 31, 2006 ͉ vol. 103 ͉ no. 44 ͉ 16059–16616 Proceedings of the National Academy ofPNAS Sciences of the United States of America www.pnas.org Cover image: Male dung beetle (Onthophagus rangifer) with branched “horns.” Beetles of this genus produce a diversity of weapons, which aid males in battles over mating opportunities with females. Females often mate with multiple males, and sperm must compete to fertilize eggs. Male beetles therefore face a trade-off between allocation of resources to horns or to testes, and this trade-off has influenced the long-term evolution of these beetles. See the article by Simmons and Emlen on pages 16346–16351. Image courtesy of Olga Helmy (University of Montana, Missoula, MT) and Douglas Emlen. From the Cover 16346 Evolutionary trade-off of weapons and testes 16068 Honey bee behavioral genomics 16079 Formaldehyde roaming mechanism 16254 Transcriptional oscillations and phenotypes 16364 Stability of inbred laboratory mice Contents INAUGURAL ARTICLE 16068 Genomic dissection of behavioral maturation in the honey bee Charles W. Whitfield, Yehuda Ben-Shahar, Charles Brillet, THIS WEEK IN PNAS Isabelle Leoncini, Didier Crauser, Yves LeConte, Sandra Rodriguez-Zas, and Gene E. Robinson ➜ See Profile on page 16065 16059 In This Issue PHYSICAL SCIENCES COMMENTARIES APPLIED PHYSICAL SCIENCES 16076 Acceleration of the recognition rate between grafted ligands and receptors with magnetic forces 16061 Skirting the transition state, a new paradigm in reaction J. Baudry, C. Rouzeau, C. Goubault, C. Robic, rate theory L. Cohen-Tannoudji, A. Koenig, E. Bertrand, Joel M. Bowman and J. Bibette ➜ See companion article on page 16079 CHEMISTRY 16063 Discovery of principles of nature from mathematical modeling of DNA microarray data 16079 Photodissociation of acetaldehyde as a second example of the roaming mechanism Orly Alter ➜ See companion article on page 16254 P. L. Houston and S. H. Kable ➜ See Commentary on page 16061 16083 Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals PROFILE Gil Goobes, Rivka Goobes, Ora Schueler-Furman, David Baker, Patrick S. Stayton, and Gary P. Drobny 16065 Profile of Gene E. Robinson 16089 The limitations on organic detection in Mars-like soils by Nick Zagorski thermal volatilization–gas chromatography–MS and their ➜ See Inaugural Article on page 16068 implications for the Viking results Rafael Navarro-Gonza´lez, Karina F. Navarro, Jose´ de la Rosa, Enrique In˜iguez, Paola Molina, Luis D. Miranda, Pedro Morales, Edith Cienfuegos, Patrice Coll, Franc¸ois Raulin, Freely available online through the PNAS open access option. Ricardo Amils, and Christopher P. McKay PNAS ͉ October 31, 2006 ͉ vol. 103 ͉ no. 44 ͉ iii–xii Downloaded by guest on September 26, 2021 ENGINEERING 16159 Different modes of SecY–SecA interactions revealed 16095 Anisotropic mechanosensing by mesenchymal stem cells by site-directed in vivo photo-cross-linking Kyle Kurpinski, Julia Chu, Craig Hashi, and Song Li Hiroyuki Mori and Koreaki Ito 16165 Enzyme–microbe synergy during cellulose hydrolysis PHYSICS by Clostridium thermocellum 16101 Liquid–crystalline aqueous clay suspensions Yanpin Lu, Yi-Heng Percival Zhang, and Lee R. Lynd Laurent J. Michot, Isabelle Bihannic, Solange Maddi, Se´rgio S. Funari, Christophe Baravian, 16170 Definition of the mitochondrial proteome Pierre Levitz, and Patrick Davidson by measurement of molecular masses of membrane proteins 16105 Breaking resolution limits in ultrafast electron Joe Carroll, Ian M. Fearnley, and John E. Walker diffraction and microscopy Peter Baum and Ahmed H. Zewail 16176 Independent and simultaneous translocation of two substrates by a nucleotide sugar transporter SUSTAINABILITY SCIENCE Carolina E. Caffaro, Carlos B. Hirschberg, and Patricia M. Berninsone 16111 Exploring the engine of anthropogenic iron cycles Daniel B. Mu¨ller, Tao Wang, Benjamin Duval, 16182 Complement activation by photooxidation and T. E. Graedel products of A2E, a lipofuscin constituent of the retinal pigment epithelium BIOLOGICAL SCIENCES Jilin Zhou, Young Pyo Jang, So Ra Kim, and Janet R. Sparrow APPLIED BIOLOGICAL SCIENCES 16188 Impaired nucleotide excision repair upon macrophage differentiation is corrected 16095 Anisotropic mechanosensing by mesenchymal stem cells by E1 ubiquitin-activating enzyme Kyle Kurpinski, Julia Chu, Craig Hashi, and Song Li Thierry Nouspikel and Philip C. Hanawalt BIOCHEMISTRY BIOPHYSICS 16117 Identification of conserved lipid͞detergent-binding sites 16076 Acceleration of the recognition rate between grafted in a high-resolution structure of the membrane protein ligands and receptors with magnetic forces cytochrome c oxidase J. Baudry, C. Rouzeau, C. Goubault, C. Robic, Ling Qin, Carrie Hiser, Anne Mulichak, R. Michael Garavito, L. Cohen-Tannoudji, A. Koenig, E. Bertrand, and Shelagh Ferguson-Miller and J. Bibette 16123 Crystal structure of a photoactivated deprotonated intermediate of rhodopsin 16083 Folding of the C-terminal bacterial binding domain in David Salom, David T. Lodowski, Ronald E. Stenkamp, statherin upon adsorption onto hydroxyapatite crystals Isolde Le Trong, Marcin Golczak, Beata Jastrzebska, Gil Goobes, Rivka Goobes, Ora Schueler-Furman, Tim Harris, Juan A. Ballesteros, and Krzysztof Palczewski David Baker, Patrick S. Stayton, and Gary P. Drobny 16129 Three strategically placed hydrogen-bonding residues 16194 Structural and dynamical changes in an ␣-subunit of a convert a proton pump into a sensory receptor heterotrimeric G protein along the activation pathway Yuki Sudo and John L. Spudich Ned Van Eps, William M. Oldham, Heidi E. Hamm, and Wayne L. Hubbell 16135 Identification of a histidine-tyrosine cross-link in the active site of the cbb3-type cytochrome c oxidase 16200 On structural transitions, thermodynamic equilibrium, from Rhodobacter sphaeroides and the phase diagram of DNA and RNA duplexes Virve Rauhama¨ki, Marc Baumann, Rabah Soliymani, under torque and tension Anne Puustinen, and Mårten Wikstro¨m Jeff Wereszczynski and Ioan Andricioaei 16141 Reaction mechanism of guanidinoacetate 16206 Monitoring intermediate filament assembly by methyltransferase, concerted or step-wise small-angle x-ray scattering reveals the molecular Xiaodong Zhang and Thomas C. Bruice architecture of assembly intermediates 16147 Functional reconstitution and characterization Anna V. Sokolova, Laurent Kreplak, Tatjana Wedig, of Pyrococcus furiosus RNase P Norbert Mu¨cke, Dmitri I. Svergun, Harald Herrmann, Hsin-Yue Tsai, Dileep K. Pulukkunat, Walter K. Ueli Aebi, and Sergei V. Strelkov Woznick, and Venkat Gopalan 16212 Structure of electron transfer flavoprotein-ubiquinone 16153 Isoelectric focusing technology quantifies protein oxidoreductase and electron transfer to the signaling in 25 cells mitochondrial ubiquinone pool Roger A. O’Neill, Arunashree Bhamidipati, Xiahui Bi, Jian Zhang, Frank E. Frerman, and Jung-Ja P. Kim Debabrita Deb-Basu, Linda Cahill, Jason Ferrante, Erik Gentalen, Marc Glazer, John Gossett, Kevin Hacker, 16218 Structure of phosphorylated enzyme I, the Celeste Kirby, James Knittle, Robert Loder, Catherine phosphoenolpyruvate:sugar phosphotransferase Mastroieni, Michael MacLaren, Thomas Mills, Uyen system sugar translocation signal protein Nguyen, Nineveh Parker, Audie Rice, David Roach, Alexey Teplyakov, Kap Lim, Peng-Peng Zhu, Geeta Kapadia, Daniel Suich, David Voehringer, Karl Voss, Jade Celia C. H. Chen, Jennifer Schwartz, Andrew Howard, Yang, Tom Yang, and Peter B. Vander Horn Prasad T. Reddy, Alan Peterkofsky, and Osnat Herzberg PNAS ͉ October 31, 2006 ͉ vol. 103 ͉ no. 44 ͉ v Downloaded by guest on September 26, 2021 16224 Yeast mitochondrial ADP͞ATP carriers are monomeric 16290 Pds1͞Esp1-dependent and -independent sister in detergents chromatid separation in mutants defective Lisa Bamber, Marilyn Harding, P. Jonathan G. Butler, for protein phosphatase 2A and Edmund R. S. Kunji Xianying Tang and Yanchang Wang 16230 An approach to crystallizing proteins by synthetic 16296 The p110␣ isoform of PI3K is essential for proper growth symmetrization factor signaling and oncogenic transformation D. Rey Banatao, Duilio Cascio, Christopher S. Crowley, Jean J. Zhao, Hailing Cheng, Shidong Jia, Li Wang, Ole V. Mark R. Fleissner, Heather L. Tienson, and Todd O. Yeates Gjoerup, Aki Mikami, and Thomas M. Roberts 16236 Role of histone tails in chromatin folding revealed 16301 Stimulatory effect of voluntary exercise or fat removal by a mesoscopic oligonucleosome model (partial lipectomy) on apoptosis in the skin of UVB Gaurav Arya and Tamar Schlick light-irradiated mice 16242 Membrane-dependent oligomeric structure and pore Yao-Ping Lu, You-Rong Lou, Bonnie Nolan, Qing-Yun Peng, formation of a ␤-hairpin antimicrobial peptide in lipid Jian-Guo Xie, George C. Wagner, and Allan H. Conney bilayers from solid-state NMR Rajeswari Mani, Sarah D. Cady, Ming Tang, Alan J. DEVELOPMENTAL BIOLOGY Waring, Robert I. Lehrer, and Mei Hong 16307 Sog͞Chordin is required for ventral-to-dorsal Dpp͞BMP 16248 General structural motifs of amyloid protofilaments transport and head formation in a short germ insect Neil Ferguson, Johanna Becker, Henning Tidow, Sandra Maurijn van der Zee, Oliver Stockhammer, Tremmel, Timothy D. Sharpe, Gerd Krause, Jeremy Cornelia von Levetzow, Rodrigo Nunes Flinders, Miriana Petrovich, John Berriman, Hartmut da Fonseca, and Siegfried Roth Oschkinat, and Alan R. Fersht 16313 Jun NH2-terminal kinase (JNK) prevents nuclear ␤-catenin accumulation and regulates axis CELL BIOLOGY formation
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