Monell Chemical Senses Center Advancing Discovery in Taste and Smell

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MONELL CHEMICAL SENSES CENTER ADVANCING DISCOVERY IN TASTE AND SMELL Media contact: Leslie Stein, 267.519.4707 or [email protected] Monell Scientist Receives AchemS Ajinomoto Award for Young Investigators in Gustation PHILADELPHIA (February 20, 2012) – Molecular biologist Ichiro Matsumoto, Ph.D., of the Monell Center, is the recipient of the 2012 Ajinomoto Award for Young Investigators in Gustation, awarded annually by the Association for Chemoreception Sciences (AChemS) to an outstanding junior scientist who is an emerging leader in the field of gustation. Matsumoto has made significant contributions to the understanding of the organization, relationships and connectivity of taste buds across a variety of vertebrate species. A recent publication in Nature Neuroscience described an important advance in understanding the differentiation and lineage of taste cells. Other studies have examined taste receptors, taste transduction, taste coding, gustatory neural pathways, gene expression in peripheral and central chemosensory systems, and clinical taste dysfunction. A highly prolific scientist, Matsumoto has published more than 50 experimental papers and more than 10 chapters and reviews. “Ichiro is an outstanding scientist whose research has had, and will continue to have, a major impact on field of gustation,” said taste biologist Alexander Bachmanov, D.V.M., Ph.D., a senior faculty member at Monell. Matsumoto joined Monell, where he currently holds the title of Research Associate, in 2009. He received his Ph.D. in molecular biology in 2003 from the University of Tokyo, where he had a junior faculty appointment at the same time he was working on his doctorate. He then held an appointment at the University of Tokyo until 2008. The award will be presented on the opening night of the 2012 AchemS Annual Meeting in Huntington Beach, CA. AChemS is an international association with over 1300 members that advances understanding of the senses of taste and smell. (more) Monell Chemical Senses Center 3500 Market St, Philadelphia, PA 19104 267.519.4700 www.monell.org The Monell Chemical Senses Center is an independent nonprofit basic research institute based in Philadelphia, Pennsylvania. Monell advances scientific understanding of the mechanisms and functions of taste and smell to benefit human health and well- being. Using an interdisciplinary approach, scientists collaborate in program areas of sensation and perception; neuroscience and molecular biology; environmental and occupational health; nutrition and appetite; health and well-being; development, aging and regeneration; and chemical ecology and communication. For more information about Monell, visit www.monell.org. Monell Chemical Senses Center 3500 Market St, Philadelphia, PA 19104 267.519.4700 www.monell.org .

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4Th International Conference on Quantitative Genetics
09/01/14 4th ICQG Conference, Edinburgh - 17-22 June 2012. • Home Programme Speakers Abstracts Satellite Events Registration Accommodation Social Programme Venue & Information Exhibitors/Sponsors Contact/News/Links EISG Satellite Site Welcome Welcome to the FourthInternational Conference of Quantitative Genetics:Understanding Variation in Complex Traits - Edinburgh International Conference Centre, 17-22 June 2012 Please click here to download We invite you to join us in the beautiful city of Edinburgh for the Fourth a copy of the Final International Conference of Quantitative Genetics, being held from Programme and Book of 17 – 22 June 2012 at the Edinburgh International Conference Centre. Abstracts Variation in quantitative and other complex phenotypes underpins most important traits in human health and disease, agriculture, natural populations and evolution. The genomics revolution has provided the tools to start the dissection of such traits, enhancing both their understanding and exploitation. This has led to an explosion of interest and new studies across all of biology. The aim will be to present and discuss state-of-the-art results, theoretical developments, understanding and methodology across the whole range of quantitative genetics - the genetic analysis and interpretation of data on complex traits - and to provide a stimulating conference in an attractive locale. Topics will include statistical methods for parameter estimation, including analysis of trait, genomic and functional genomic data; methods for QTL and gene identification; genetic control of complex traits; prediction of breeding value and individual risk, and interpretation of evolutionary change. The meeting will pertain to and span results from, for example, humans, livestock, crops, micro-organisms and natural and experimental populations of all species.
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Glucose Transporters and ATP-Gated K Metabolic Sensors Are
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Journal of Heredity 2009:100(Supplement 1):S90–S100 Ó The American Genetic Association. 2009. All rights reserved. doi:10.1093/jhered/esp015 For permissions, please email: [email protected]. Advance Access publication April 14, 2009 Analyses of Sweet Receptor Gene (Tas1r2) and Preference for Sweet Stimuli in Species of Carnivora XIA LI,DIETER GLASER,WEIHUA LI,WARREN E. JOHNSON,STEPHEN J. O’BRIEN,GARY K. BEAUCHAMP, AND JOSEPH G. BRAND From the Monell Chemical Senses Center, Philadelphia, PA 19104 (Xia Li, Weihua Li, Beauchamp, and Brand); the Anthropological Institute and Museum, University of Zurich, Zurich, Switzerland (Glaser); the Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD (Johnson and O’Brien); the Department of Psychology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA (Beauchamp); Department of Anatomy, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA (Beauchamp); the Department of Biochemistry, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA (Brand). Address correspondence to Xia Li or Joesph Brand at the address above, or e-mail: [email protected]; [email protected]. Abstract The extent to which taste receptor speciﬁcity correlates with, or even predicts, diet choice is not known. We recently reported that the insensitivity to sweeteners shown by species of Felidae can be explained by their lacking of a functional Tas1r2 gene. To broaden our understanding of the relationship between the structure of the sweet receptors and preference for sugars and artiﬁcial sweeteners, we measured responses to 12 sweeteners in 6 species of Carnivora and sequenced the coding regions of Tas1r2 in these same or closely related species.
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1 Making Organisms Model Human
ORE Open Research Exeter TITLE Making organisms model human behavior: Situated models in North-American alcohol research, since 1950 AUTHORS Ankeny, Rachel A.; Leonelli, Sabina; Nelson, Nicole C.; et al. JOURNAL Science in Context DEPOSITED IN ORE 15 January 2015 This version available at http://hdl.handle.net/10871/16166 COPYRIGHT AND REUSE Open Research Exeter makes this work available in accordance with publisher policies. A NOTE ON VERSIONS The version presented here may diﬀer from the published version. If citing, you are advised to consult the published version for pagination, volume/issue and date of publication Making Organisms Model Human Behavior: Situated Models in North-American Alcohol Research, 1950-onwards Final version accepted for publication in April 2013. Forthcoming in Science in Context. Sabina Leonelli*, Senior Lecturer, Department of Sociology and Philosophy, University of Exeter, St Germans Road, EX4 4PJ Exeter, UK, [email protected] Rachel A. Ankeny, Associate Professor, School of History & Politics, University of Adelaide, Napier 423, Adelaide 5005 SA, Australia, [email protected] Nicole C. Nelson, Postdoctoral Fellow, Department of Social Studies of Medicine, McGill University, 3647 Peel Room 207, Montreal QC, H3A 1X1, Canada, [email protected] Edmund Ramsden, Research Fellow, Centre for the History of Science, Technology and Medicine, Faculty of Life Sciences, University of Manchester, Simon Building, Manchester, M13 9PL, UK [email protected] *Corresponding author 1 Argument: We examine the criteria used to validate the use of nonhuman organisms in North-American alcohol addiction research from the 1950s to the present day. We argue that this field, where the similarities between behaviors in humans and non- humans are particularly difficult to assess, has addressed questions of model validity by transforming the situatedness of non-human organisms into an experimental tool.
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(T1r3)-Expressing Taste Cells
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