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C. elegans development, cell biology and gene expression 13 – 17 June 2018 | Barcelona, Spain Abstract Book meetings.embo.org/event/18-c-elegans Logo design: Ahna Skop T-shirts, mugs, bags, and other items with the Barcelona C. elegans meeting logo can be ordered online: https://www.cafepress.com/celegans/15377503 https://www.cafepress.com/celegans/15377551 2 Program & Abstract Book EMBO workshop C. elegans Development, Cell Biology & Gene Expression Combined C. elegans Topic Meeting and European C. elegans meeting June 13 - 17, 2018 Meeting Organizers • Sander van den Heuvel. Utrecht University, NL • Sophie Jarriault. IGBMC, FR • Alex Hajnal. University of Zurich, CH Co-Organizers • Julian Ceron. Bellvitge Biomedical Research Institute - IDIBELL, ES • Luisa Cochella. Research Institute of Molecular Pathology (IMP), AT • Ben Lehner. Centre for Genomic Regulation, ES Scientific Committee • Erik Anderson, Northwersten University, USA • Michael Barkoulas, Imperial College London, UK • Henrik Bringmann, Max Planck Institute for Biophysical Chemistry, DE • Olivia Casanueva, Babraham Institute, UK • Julian Ceron, Bellvitge Biomedical Research Institute-IDIBELL, ES • Barbara Conradt, Ludwig-Maximilians-Universität München, DE • Thorsten Hoppe, University of Cologne, DE • Jane Hubbard, Skirball Institute of Biomolecular Medicine, USA • Janine Kirstein, FMP Berlin, DE • Ben Lehner, Centre for Genomic Regulation, ES • Christian Pohl, Goethe-Universität Frankfurt, DE • Benjamin Podbilewicz, Technion Israel Institute of Technology, IL • Ahna Skop, Wisconsin University, USA • Asako Sugimoto, Tohoku University, JP • Baris Tursun, MDC Berlin, DE 3 PROGRAM AT A GLANCE 09:00 - 10:10 09:00 - 10:10 09:00 - 10:10 09:00 - 10:10 Auditorium Auditorium Auditorium Auditorium Session 2a Session 5a Session 7a Session 10a Germline, Epigenetics & Sex Morphogenesis Cell fate II (Neuronal) & Ageing Determination Behaviour 10:10 - 10:35 10:10 - 10:35 10:10 - 10:35 10:10 - 10:35 Coffee break Coffee break Coffee break Coffee break 10:35 - 11:35 10:35 - 11:35 10:35 - 11:40 10:35 - 11:35 Auditorium Auditorium Auditorium Auditorium Session 2b Session 5b Session 7b Session 10b Germline, Epigenetics & Sex Morphogenesis Cell fate II (Neuronal) & Ageing Determination Behaviour 11:35 - 13:00 11:35 - 13:00 11:35 - 11:45 LunCh LunCh 11:40 - 13:00 Auditorium LunCh Closing 13:00 - 14:10 13:00 - 14:10 13:00 - 13:55 Auditorium Auditorium Auditorium Session 3a Session 6a Session 8a Cell Biology & Early Development Evolution & Natural variation Metabolism & Microbe-host interactions 13:55 - 14:20 14:10 - 14:35 14:10 - 14:35 Break Break Break 14:20 - 15:20 Auditorium Session 8b 14:35 - 15:40 14:35 - 15:30 Metabolism & Microbe-host Auditorium Auditorium interactions Session 3b Session 6b Cell Biology & Early Development Evolution & Natural Variation 15:20 - 15:45 Coffee break 15:30 - 18:00 15:40 - 16:05 Port Vell Room Coffee break Poster session II 15:45 - 17:00 Session 9 DNA repair & Cell Death 16:05 - 17:15 17:00 - 17:10 Auditorium Auditorium Session 4a Opening of the meeting Cell Fate I (postembryonic) 17:10 - 18:25 Auditorium 17:15 - 17:40 Session 1a Break Genomics & Systems Biology 17:40 - 18:35 Auditorium 18:00 - 18:30 Session 4b Auditorium 18:25 - 18:55 Cell Fate I (postembryonic) Keynote address Coffee break Worm Tales 18:35 - 21:05 18:30 - 19:30 18:55 - 20:00 Port Vell Room Auditorium Auditorium Poster session I Special keynote lecture Session 1b Genomics & Systems Biology 20:00 - 21:00 20:00 WelCome Mixer ConferenCe Dinner 4 GENERAL INFORMATION Venue World Trade Center Barcelona Moll de Barcelona s/n, East building, 1st Floor, Port Vell Room 08039, Barcelona (Spain) Auditorium Registration and Information Desk The conference registration desk will be open according to the following schedule: Date Time Location Wednesday, June 13 13:00 – 20:00 Auditorium Hall Thursday, June 14 08:30 – 18:00 Auditorium Hall Friday, June 15 08:30 – 19:30 Auditorium Hall Saturday, June 16 08:30 – 17:00 Auditorium Hall Sunday, June 17 08:30 – 11:45 Auditorium Hall Internet Free WiFi is available throughout the Auditorium. User: EMBO. Password: BCN2018 Cameras, Cell Phones and Video Recording Devices In order to protect unpublished data, the use of cameras and other recording devices in oral and poster sessions is prohibited. Badges Badges are required for admission to all sessions, posters, exhibit hall, and reception. If you lose your badge, a duplicate can be printed at the Conference Registration Desk for 5€. Certificates of Attendance All Certificates (attendance, oral talks and posters) will be sent through the meeting webpage. 5 Poster Competition Poster prizes will be awarded only among postdocs and graduate students. Judges attempt to visit each poster when the authors are scheduled to present. The competition is open to postdocs and graduate student that are the first and presenting author on the poster. Platform sessions: All talks will be presented in the WTC auditorium. Instructions for speakers: Time allocation: Speakers selected from the abstracts have been notified about the length of their talk: 15 minutes (12 min presentation and 3 min. discussion), or 5 minutes (short, poster pitch style. Questions and discussion during the poster session). Other oral presentations: Special Keynote: 1 hour (50 min. presentation, 10 min discussion) Keynote address: 30 minutes (25 min. presentation, 5 min. discussion) Session keynotes: 35 minutes (30 min. presentation, 5 min. discussion) Invited session speakers: 25 minutes (20 min. presentation, 5 min discussion) Please make sure your talk does not take more time than allotted, as the schedule is tight. Audio-visual All presentations should be loaded directly onto a meeting computer at the technician cabin of the Auditorium. A Mac and PC will be available, with applications to support presentations in Powerpoint, Keynote or pdf format. In the interest of time, personal computers cannot be used for the presentations. Presenters should bring their presentation on a USB drive and upload it well before the session in which they speak starts: morning sessions, the day before – afternoon sessions, the day before or at the end of the morning session during the lunch break. A technician will be available in the afternoon of June 13, during lunch breaks and following sessions. Please name your presentation with the session number and your last name. The presenters should test their presentation together with the technician. Please embed movies into the presentation, but also bring them in a separate folder, to allow re-inserting and adjusting the format should problems arise. The speakers will have a remote control with forward and reverse keys, which work like the left and right arrows on a keyboard, and can be used to start an animation/movie with an extra click. Please arrive at the auditorium 10-15 minutes before the beginning of your session to have the chance to meet your session chair and receive some last-minute information if needed. 6 Poster Sessions All posters will be presented in the Port Vell Room. There will be two poster sessions. The poster space will be 90 x 120 cm (width x height), which corresponds to A0 vertical format (or 16 pages in A4 format). Push pins will be available at the main entrance to the poster session. Thursday June 14, 18.30-21.00 hr. Poster session I, Odd-numbered posters. Friday June 15, 15.30-18.00 hr. Poster session II, Even-numbered posters Poster numbers can be found in the abstract book and in the pdf available at the website. All posters will be up for one day, and should be removed at the end of the poster session. After that time, posters will be removed and may be lost or discarded. The venue does not take responsibility for posters that are not removed on time. Social Events The Welcome mixer will take place Wednesday, 13 June at 20:00 at the Hotel Eurostars Grand Marina The Conference dinner will take place Saturday, 16 June at 20:00 at the restaurant Chicken Bar (Carrer Marina, 16 C.P. 08005 Barcelona, see map) To register for this dinner, an email poll will be sent: please respond by indicating whether you will or will not come to the conference dinner. Party: Dinner will be followed by a music and dance party, until 1.00 am in the same venue. 7 PROGRAM Wednesday, 13 June 2018 Opening of the Meeting, General Information Sander van den Heuvel, Utrecht University, NL 17:00-17:10 Sophie Jarriault, IGBMC, FR Alex Hajnal, University of Zurich, CH Session 1 Genomics & Systems Biology Chair: Ben Lehner, CRG, ES S1-01 Genome architecture and regulation 17:10-17:45 Julie Ahringer, Wellcome Trust/Cancer Research UK Gurdon Institute, UK S1-02 A comprehensive spatiotemporal map of embryonic gene expression 17:45-18:00 Qin Zhu, Hannah Dueck, Priya Sivaramakrishnan, Amanda Zacharias, Shaili Patel, Elicia Preston, Junhyong Kim, John Murray S1-03 Spatially-resolved transcriptomics in C. elegans identifies sex-specific 18:00-18:15 differences in gene expression patterns Annabel L. P. Ebbing, Abel Vertesy, Marco Betist, Bastiaan Spanjaard, Jan Philipp Junker, Eugene Berezikov, Alexander van Oudenaarden, Hendrik C. Korswagen S1-04 Quantitative RNA-seq meta analysis of alternative exon usage in C. 18:15-18:20 elegans. Denis Dupuy, Nicolas Tourasse S1-05 Systematic analysis of cell cycle phases reveals only a single cell pair 18:20-18:25 develops with full cell cycle during C. elegans embryogenesis Ming-Kin Wong, Vincy Wing Sze Ho, Xiaotai Huang, Runsheng Li, Lu-yan Chan, Hon Chun Kaoru Ng, Hong Yan, Zhongying Zhao 18:25 - 18:55 Coffee break S1-06 C. elegans locomotion 18:55-19:20 Andre Brown, Imperial College London, UK S1-07 Gene expression of an animal germline near single cell resolution 19:20-19:35 Asija Diag, Marcel Schilling, Filippos Klironomos, Nikolaus Rajewsky S1-08 Application of Imaging mass spectrometry for C.