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VENUE GROUPCONTENTS NAME: UCAR Conference room Department of Nuclear Medicine, OUH 4 Program 71 Larsen Group 5 Meeting attendees 74 Meyer Group 7 Strategy 80 Nielsen 17 BRIDGE 83 Neuroepidemiology 22 Asgari Group 89 Neuroimmunology 27 BWK Brain Cancer Research Group 94 Neurosurgical research Group 31 Cellular Neurobiology 98 Owens Group 37 Child and Adolescent Psychiatric 103 Peripheral Neuropathy 41 The Danish Aging Research Center 108 T-Pemf and parkinsonism Group 45 Department of epilepsy genetics and 114 TRANSIC personalized medicine 123 Translational neuroscience Group 51 Finsen Group 128 UCAR 59 Focused Research Group in neurology 133 Posters 63 Gerlach Group 66 Lambertsen Group 4 VENUE PROGRAMGROUP NAME: JUNE UCAR 12TH Conference room Department of Nuclear Medicine, OUH TIME SESSION 1: INTRODUCTION – KIM BRIXEN, MEDICAL DIRECTOR, OUH 09:00-09:10 PRESENTER 09:10-09:20 Brain Cancer – Bjarne Winther Kristensen 09:20-09:30 Neuroimaging – Poul Flemming Højlund Carlsen and Albert Gjedde 09:30-09:40 Alcohol– Anette Søgaard Nielsen 09:40-09:50 Psychiatry - Tanja Michel 09:50-10:25 DISCUSSION PANEL Bjarne Winther Kristensen, Poul Flemming Højlund-Carlsen, Anette Søgaard Nielsen, Tanja Michel, Frantz Rom Poulsen, Albert Gjedde, Kate Lykke Lambertsen 10:25-10:35 BREAK SESSION 2: INTRODUCTION - OLE SKØTT, DEAN HEALTH SCIENCE SDU 10:35-10:45 PRESENTER 10:45-11:00 Neuroinflammation - Trevor Owens 11:00-11:10 Stem cells and neurodegenerative diseases - Morten Meyer 11:10-11:20 Neuroepidemiology - David Gaist 11:20-11:30 Demyelinating diseases - Zsolt Illes 11:30-12:00 DISCUSSION PANEL Trevor Owens, Morten Meyer, David Gaist, Bente Finsen, Zsolt Illes, Åsa Fex-Svenningsen, Søren Sindrup, Kate Lykke Lambertsen 12:00-13:00 LUNCH AND POSTER SESSION 5 VENUE MEETINGGROUP NAME: ATTENDEES UCAR Conference room Department of Nuclear Medicine, OUH THE LUNDBECK • Professor Kim Krogsgaard, Managing Director, The Brain Prize, FOUNDATION The Lundbeck Foundation • Dr. med. Sissel Vorstrup, Associate Director of Research, The Lundbeck Foundation • Ph.d. Line Vilbrad Knudsen, Science Liaison, The Brain Prize, The Lundbeck Foundation • Professor, Sir Colin Blakemore, University of London • Professor Martin Rossor, University College London OUH, SDU AND • Professor Ole Skøtt, Dean at the Faculty of Health Sciences, SDU MENTAL HEALTH • Professor Kim Brixen, Medical Director, OUH SERVICES IN • Professor Kirsten Kyvik, Head of Department, Department of Clinical THE REGION Research, SDU OF SOUTHERN • Professor Uffe Holmskov, Head of Department, Department of Molecular DENMARK Medicine, SDU • Associate Professor Rikke Leth-Larsen, Head of Department, Department of Regional Health Research, SDU • MSc Marie Lund, Head of Department, Department of Quality, Research, Innovation and Education, OUH • Associate professor Kate Lykke Lambertsen, Lundbeck Brain Prize Council Representative at SDU SESSION 1: • Professor Bjarne Winther Kristensen, Department of Pathology, OUH • Professor Poul Flemming Højlund Carlsen, Department of Nuclear Medicine, OUH • Professor Albert Gjedde, Department of Nuclear Medicine, OUH • Associate Professor Anette Søgaard Nielsen, Mental Health Services, Region of Southern Denmark • Professor Tanja Michel, Mental Health Services, Region of Southern Denmark • Professor Frantz Rom Poulsen, Department of Neurosurgery, OUH SESSION 2: • Professor Trevor Owens, Department of Molecular Medicine, SDU • Associate Professor Morten Meyer, Department of Molecular Medicine, SDU • Professor David Gaist, Department of Neurology, OUH • Professor Zsolt Illes, Department of Neurology, OUH • Professor Bente Finsen, Department of Molecular Medicine, SDU • Associate Professor Åsa Fex-Svenningsen, Department of Molecular Medicine, SDU • Professor Søren Sindrup, Department of Neurology, OUH Neuroscience at the Faculty of Health Sciences, SDU, OUH and the Region of Southern Denmark 7 Neuroscience at the Faculty of Health Sciences, VENUE SDU, OUHGROUP and the RegionNAME: of Southern UCAR Denmark Conference room Department of Nuclear Medicine, OUH INTRODUCTION The University of Southern Denmark (SDU), Odense University Hospital (OUH) and the Region of Southern Denmark (RSD) wish to maintain and develop the region as an area with hospitals and a university that have a visible and decisive influence on research, the health care system and public health. We focus on translational research to facilitate interaction between basic health research and clinical practice. This is supported by strong collaborations between OUH, Mental Health Services (MHS) in RSD, institutes under the Faculty of Health Sciences, and the Faculty of Science, SDU. When the New OUH is completed in 2022 it will be connected to the existing SDU by a new Faculty of Health Science. Translational research will enjoy extraordinarily good conditions in the close linkage between the university and the university hos- pital. The interaction between foundation-creating research subjects at SDU and the clinical subjects at OUH provides an example of translational research. New OUH/SDU will create synergies between the university and the university hospital, with the goal of creating even better research, better treatment and better edu- cation. Ultimately, it will also contribute to improving human health, which is the declared visionary goal of the Faculty of Health Sciences and futher the ambion of OUH - The Patient First. The neuroscience at SDU, OUH, MHS and the regional hospitals is gathered together under the newly established BRIDGE initiative (Brain Research-Inter-Disciplinary Guided Excellence). BRIDGE was established with the aim of hosting a network of researchers with clinical expertise and scientific excellence in neuroscience. The center brings together the diverse research interests of members of a core research team who will work under the common umbrella of a neuroscience approach and neurobehavioral research methodologies. The vision of BRIDGE is to improve patient treatment and promote early intervention and the prevention of brain disorders patient by using translational research to harness the power of discovery science. We aim to establish a separate building for BRIDGE at the new university hospital. 8 Neuroscience at the Faculty of Health Sciences, VENUE SDU, OUHGROUP and the RegionNAME: of Southern UCAR Denmark Conference room Department of Nuclear Medicine, OUH INTERACTIONS Interactions between neuroscience researchers are facilitated by: • Communication of research ideas and findings facilitated by regular seminars within BRIDGE • An annual Neurotranslational meeting facilitating new collaborations and giving people from SDU, OUH, and RSD the opportunity to meet and discuss research. • Upcoming joint meetings for senior researchers within neuroscience at SDU, OUH, and RSD. The purpose is to facilitate and strengthen collaborations, to promote research strategies, and to discuss common applications. • Cross-affiliations and cross-appointments between OUH and SDU INFRASTRUCTURE Our neuroscience infrastructure includes: • The Biomedical Laboratory (BL) is the central animal facility for Health Sciences, Natural Sciences and OUH. The department is involved in experimental biomedical research, surgical skills courses, training and research in labora- tory animal science at SDU, OUH and the regional hospitals. This is a world- class facility for animal research including rodents, rabbits, dogs, pigs and sheep and is headed by Associate Professor Peter Bollen together with veterinarian Louise Langhorn. • The IMM Flow Cytometry and Confocal Microscopy Core Facility serve all research groups at SDU and OUH as well as non-university users. • The Department of Human Genetics at OUH provides DNA and RNA sequencing and array screening services. • A small animal PET/CT scanner, which is part of the Danish Molecular Bioimaging Center (DaMBIC) at SDU, is operated in collaboration with the Biomedical Laboratory. • OPEN (Odense Patient data Explorative Network) offers access to databases, biobanks and use of registry data as well as general advice related to research projects. • Department of Nuclear Medicine, OUH, is an interdisciplinary clinical depart- ment serving almost all medical specialties and all departments at OUH and SDU. The department is equipped with gamma cameras, SPECT/CT scanners, and PET/CT scanners as well as its own Cyclotron and radiochemical laborato- ries for production and development of a variety of PET tracers. 9 Neuroscience at the Faculty of Health Sciences, VENUE SDU, OUHGROUP and the RegionNAME: of Southern UCAR Denmark Conference room Department of Nuclear Medicine, OUH NEUROSCIENCE The Department of Clinical Research is the largest department at The Faculty of AT OUH AND THE Health Sciences – but the entire department is physically located at OUH, where DEPARTMENT research and clinical experience are directly related. The Faculty of Health Sciences OF CLINICAL RESEARCH, SDU is thus essential for research at OUH, and the clinical environment is essential for the research. The Department of Clinical Research was established in 1989 and constitutes the university affiliation of the researchers and lecturers working at OUH. The Institute includes 42 research departments and is headed by Professor Kirsten Ohm Kyvik. Strategy OUH and the Department of Clinical Research, SDU, have in collaboration prepared an ambitious research strategy for the period 2016-2020. A major focus in the strategy is involving patients and relatives in research. OUH's motto 'The Patient