AUTHOR INDEX December 1980 Abeloff, MD

AUTHOR INDEX

December 1980

Abeloff, M. D., 4420 Garson, O. M., 4826 Leserman, L. D., 4768 Russell, D. H., 4373 Abrams, P. G., 4356 Gazdar, A. F., 4356 Levitt, D. S., 4456 Adler, K. B., 4403 George, R., 4717 Levy, J. A., 4364 Sakurai, M., 4826 Aldenderfer, P., 4420 GÃ©rard,G. F., 4398 U, G. C., 4501 Saladik, D., 4433 Alimena, G., 4826 Oilman, S. C., 4640 Loewenstein, P. M., 4398 Sandberg, A. A., 4512, 4826 Amin, S., 4528 Giuliani, F. C., 4682 Lyon, l., 4606 Sanford, K. K., 4415 Anderson, C., 4519 Gold, A., 4482 Sasaki, K., 4810 Anderson, S. N., 4571 Goldenberg, G. J., 4489 Maclntyre, l., 4764 Sasaki, M. S., 4796 Goldfarb, S., 4717 Maekawa, T., 4813 Sattler, C. A., 4552 Andrews, J. P., 4688 Mak, W. W-N., 4552 Arafah, B. M., 4628 Golomb, H. M., 4826 Shimano, T., 4658 Gordon, C., 4546 Manabe, H., 4791 Shrivastav, S., 4438, 4443 Bachur, N. R., 4669 Gordon, R. E., 4467 Manni, A., 4628 Simms, E., 4356 Bainton, D. F., 4473 Graham, D., 4482 Martin, T. J., 4764 Skipper, P. L., 4704 Baker, M. H., 4734 Grayhack, J. T., 4524 Mashiba, H., 4791 Smith, G. L, 4368 Matsui, S-i., 4512 Baker, N., 4606 Greco, W. R., 4617 Smith, l. E., 4734 Banerjee, M. R., 4368 Greenberg, P. D., 4428 Matsumoto, K., 4781 Smyth, J. F., 4734 Barthold, S. W., 4451 Grier, A. H.,441 5 Matsushima, T., 4775 Sokal, G., 4826 Meade-Cobun, K. S., 4519 Bech, D.,4451 Groopman, J. D., 4343 Somer, K. D., 4410 Bedenke, V., 4528 Grover, J., 4489 Memoli, V. A., 4571 Sorof, S., 4688 Begleiter, A., 4489 Cullino, P. M., 4628 Meyer, L. W., 4599 Speck, W. T., 4599 Bhatt, R. S., 4581 Michelangeli, V. P., 4764 Stanley, J. R., 4694 Bialkowski, S., 4617 Haglund, U., 4786 Minna, J. D., 4356 Sternberg, S. S., 4546 Bishop, W. W., 4704 Hahn, G. M., 4501 Mitelman, F., 4826 Stone, K. R., 4438, 4443 Blackburn, G. R., 4688 Hawley-Nelson, P., 4694 Miura, T., 4813 Sun, A. S., 4677 Blumer, J. L., 4599 Hayata, I., 4781 Miyamoto, K., 4751 Bonar, R. A., 4438, 4443 Hayder, S., 4786 Mokyr, M. B., 4565 Takahashi, K., 4775 Boreiko, C., 4709 Hecht, S. S., 4528 Mondai, S., 4709 Takahashi, M., 4810 BorgstrÃ¶m, G. H., 4826 Heidelberger, C., 4581, 4709 Moore, J. J., 4768 Takenaka, K., 4791 Boynton, A. L., 4541 Hellman, S., 4335 Moore, M., 4482 Tan, C., 4546 Brandt, L., 4826 Henneberry, M. O., 4524 Moseley, J. M., 4764 Tannenbaum, S. R., 4704 Bryant, B. M., 4734 Herbst, A. L., 4612 Mossman, B. T., 4403 Tarone, R. E., 4415 Bugelski, P., 4460 Hess, A. D., 4495 Muller-Eberhard, U., 4456 Telfer, N., 4581 Busby, W. F., Jr., 4343 Hoffmann, D., 4528 Murphy, G. P., 4658 Terasaki, T., 4751 Hoffman, H. A., 4415 Murphey, M. M., 4410 Terry, W. D., 4768 Cabrai, J. R. P., 4739 Horaguchi, K., 4775 Thilly, W. G., 4704 Calderwood, S. K., 4728 Hosick, H. L., 4631 Naganuma, K., 4758 Thorgeirsson, S. S., 4456 Catovsky, D., 4826 Hossfeld, D. K., 4826 IMarayan, K. S., 4709 Todaro, G. J., 4722 Cederbaum, A. l., 4677 Howard, B., 4482 Narita, N., 4781 Tohda, H., 4775 Check, l. J., 4612 Howard, E. F., 4385 Nayar, K. T., 4364 Tomida, M., 4804 Cheever, M. A., 4428 Howard, J. S., 4385 Neal, G. E., 4739 Tompkins, W. A. F., 4744 Cheng, C. Y., 4385 Hozumi, M., 4804 Nelson, J. A., 4381 Topping, D. C., 4352 Chou, T-C., 4546 Hreshchyshyn, M. M., 4512 Nesnow, S., 4482 Tsukagoshi, S., 4758 Chu, T. M., 4658 Hunter, R. L, 4612 Nettesheim, P., 4352 Tsunematsu, Y., 4796 Clarke, A. A., 4640 Husby, G., 4648 Nishiura, T., 4658 Tsuruo, T., 4758 Clawson, R. E., 4669 Nogiwa, E., 4813 Tung, K. S. K., 4648 lida, H., 4758 Cohen, J. L., 4669 Nomura, Y., 4791 Tyagi, A. K., 4390 Iribe, H., 4791 Cooney, D. A., 4390 O'Brien, T. G., 4433 Craighead, J. E., 4403 Iyer, A. P., 4368 Uchida, N., 4781 Craven, P. A., 4589 lype, P. T., 4663 Oikawa, A., 4775 Utsumi, J., 4796 Curtis, G., 4482 Okamoto, S., 4781 Utsunomiya, J., 4796 Jarman, M., 4734 Oison, J. W., 4373 O'Neill, B., 4364 Danielson, K. G., 4631 Johnson, E. F., 4456 Valenzuela, L., 4658 Dave, S., 4617 Jones, G. M., 4415 Oyasu, R., 4524 van den Berghe, H.. 4826 Dawson, J. R., 4495 van Orshoven, A., 4826 de la Chapelle, A., 4826 Kaku, M., 4791 Papsidero, L. D., 4658 Verwilghen, R., 4826 DeRubertis, F. R., 4589 Kannan, R., 4606 Parshad, R., 4415 Vuopio, P., 4826 Dewald, G. W., 4826 Kaplan, N. O., 4682 Pauli, B. U., 4571 Dickson, J. A., 4728 Kaszubowski, P. A., 4648 Paulson, D. F., 4438, 4443 Waalkes, T. P., 4420 Kelly, E., 4533 Pavelic, Z. P., 4617 Wake, N., 4512 Dittman, W. A., 4473 Keski-Oja, J., 4722 Docherty, J. J., 4640 Pearson, O. H., 4628 Wang, M. C., 4658 Dowdle, E. B., 4817 Killian, C. S., 4658 Philips, F. S., 4546 Warrell, R. P., Jr., 4546 Dray, S., 4565 Kirsh, R., 4460 Pierre, R. V., 4826 Webster, L. T., Jr., 4599 Kitamura, Y., 4781 Pitot, H. C., 4552 Weigent, D. A., 4381 Egorin, M. J., 4669 Knauer, D. J., 4368 Piver, S. M., 4512 Weinstein, J. N., 4768 Eisenstadt, E., 4482 Koehler, B., 4694 Pleshkewych, A., 4533 Whitehead, R., 4764 Eisman, J. A., 4764 Kouri, R. E., 4364 Pontzer, C. H., 4663 Whitfield, J. F., 4541 Ettinger, D. S., 4420 Krahenbuhl, J. L., 4622 Porter, C. W., 4533 Williams, R. C., Jr., 4648 Ezerman, E. B., 4403 Kramer, D. L., 4533 Poste, G., 4460 Wilson, E. L., 4817 Kramer, R. J., 4473 Priore, R. L., 4617 Wogan, G. N., 4343 Fairchild, E., 4599 Kruuv, J., 4485 Pzepiorka, D., 4565 Woo, K. B., 4420 Fefer, A., 4428 Kuettner, K. E., 4571 Feinberg, A., 4446 Kurashige, S., 4813 Rao, K. V. K., 4688 Yagawa, K., 4791 Fidler, l. J., 4460 Kuriyama, M., 4658 Rawls, W. E., 4640, 4744 Yamagata, J., 4791 Findlay, D. M., 4764 Kyriazis, A. A., 4509 Raz, A., 4460 Yamaguchi, K., 4781 Fogler, W. E., 4460 Kyriazis, A. P., 4509 Roberts, J., 4546 Yamamoto, Y., 4804 Romic-Stojkovic, R., 4821 Frampton, R. J., 4764 Yasumoto, K., 4791 Friedman, A., 4599 Landolph, J. R., 4581 Rosenberg, K. D., 4612 Young, C. W., 4546 Furth, E. E., 4704 Lane, B. P., 4467 Rosenthal, K. L., 4744 Yuspa, S. H., 4694 Lange, G. W., 4398 Ross, L. A., 4669 Gall, S. A., 4495 LaVoie, E. J., 4528 Rowland, R. G., 4524 Zamora, P. O., 4631 Gamulin, S., 4821 Lawler, S. D., 4826 Rowley, J. D., 4826 Zech, L., 4786 Garland, H., 4482 Lepock, J. R., 4485 Ruddon, R. W., 4420, 4519 Zedeck, M. S., 4446

DECEMBER 1980 4837

[CANCER RESEARCH 40, 4839-4868. December 1980]

Index to Volume 40

Author Index

834; Weeks, Allaben, Tresp, Louie, Lazear, and Pearson, O. H. Effect of Ovariectomy on Hor King, 1204 mone Receptors and Growth of W-Nitrosometh- Abdelfattah-Gad, M. See Denk, Abdelfattah-Gad, Allegra, J. C. See DeWys, Allegra, Simon, and ylurea-induced Mammary Tumors in the Rat, Eckerstorfer, and Talcott, 2568 Lippman, 2423 4628 AbÂ«,S., and Sandberg, A. A. Sister Chromatid Allen, L. M., and Thornthwaite, J. T. Studies on Arakawa, M. See Fukuda, Shindo, Shimizu, Ar- Exchange and Growth Kinetics of Marrow Cells the Pharmacology and Cytokinetics of 1H-lm- akawa, and Mizuhira. 133 in Aneuploid Acute Nonlymphocytic Leukemias, adazo[1,2-b]pyrazolo (NSC-51143) with P815 Araki, E. See Gasa. Makita, Kameya, Kodama, 1292 Mastocytoma Cells, 4059 Araki, Yoneyama, Hirama, and Hashimoto, Abeloff, M. D. See Baylin, Abeloff, Goodwin, Car Allen, P. T. See Strickland, Saviolakis, Weislow, 3804 ney, and Gazdar, 1990; Waalkes, Abeloff, Woo, Allen, Hellman, and Fowler, 3570 Archibald, L. See Adams, Archibald, and Sey Ettinger, Ruddon, and Aldenderfer, 4420 Allfrey, V. G. See Boffa, Diwan, Grass, and Allfrey, mour-Munn, 3815 Abrams, P. G. See Simms, Gazdar, Abrams, and 1774 Ardalan, B., Cooney, D. A., Jayaram, H. N., Car- Minna, 4356 Alpert, E. See Kim, DeLand, Nelson, Bennett, rico, C. K., Glazer, R. l., Macdonald, J., and Accolla, R. S. See Carrel, Accolla. Carmagnola, Simmons, Alpert, and Goldenberg, 3008' Schein, P. S. Mechanisms of Sensitivity and and Mach, 2523 Althouse, R., Huff, J., Tomatis, L., and Wilbourn, Resistance of Murine Tumors to 5-Fluorouracil, Acs, G. See Mendelsohn, Gilbert, Christman, and J. An Evaluation of Chemicals and Industrial 1431 Acs, 1469; Mendelsohn, Michl, Gilbert, Acs, Processes Associated with Cancer in Humans Arlett, C. F., and Harcourt, S. A. Survey of Radi- and Christman, 3206 Based on Human and Animal Data: IARC Mon osensitivity in a Variety of Human Cell Strains, Adams, J. B. See Pewnim, Adams, and Ho, 1360 ographs Volumes 1 to 20, page 1 926 Adams, J. B., Archibald, L., and Seymour-Munn, Altman, A. See Von Hoff, Casper, Bradley, Trent, Arlin, Z. A., Sklaroff, R. B., Gee, T. S., Kempin, K. Dehydroepiandrosterone and Androst-5-ene- Hodach, Reichert, Makuch, and Altman, 3591 S. J., Howard, J., Clarkson, B. D., and Young, 3/J,17/?-diol in Human Mammary Cancer Cytc- Altman, N. H. See Radomski, Deichmann, Altman, C. W. Phase I and II Trial of 4'-(9-Acridinyla- solic and Nuclear Compartments and Their Re and Radomski, 3537 mino)methanesulfon-m-anisidide in Patients lationship to Estrogen Receptor, 3815 Amare, M. See Park, Amare, Savin, and Hoogs- with Acute Leukemia, 3304 Adams, L. M. See Kennel. Lankford, Foote, Tsak- traten, 1062 Armbrecht, H. J. See Zenser, Mattammal, Arm eres. Adams, and Ullrich. 2153 Amin, S. See LaVoie, Hecht, Amin, Bedenke, and brecht, and Davis, 2839 Adamson, D. J. See Wheeler, Alexander, and Hoffmann, 4528 Armstrong, R. D., and Oiasio, R. B. Metabolism Adamson, 3723 Amltani, K. See Nakata, Ochi, Kurisaki, Okano, and Biological Activity of S'-Deoxy-S-Fluorouri- Adcock, R. A. See Spratt, Adcock, Muskovin. Hamada, Amitani, Tanabe, Ono, and Sakamoto. dine, a Novel Fluoropyrimidine, 3333 Sherrill, and McKeown, 256; Spratt, Adcock. 127 Arnold, L. J. See Theiss, Arnold, and Shimkin, Sherrill, and Travathen, 253 Anderson, C. See Ruddon, Anderson, and 4322 Adegbite, M. See Hersh, Patt, Murphy, Dicke, Meade-Cobun, 4519 Arya, S. K. See StrÃ¤uchen,Arya, Tralka, Engel, Zander, Adegbite, and Goldman, 3134 Anderson, K. M., Bonomi, P., Marogil, M., Hen- and Young, 3880 Adkinson, L. See Coggin, Adkinson, and Ander drickson, C., and Economou, S. Comparison Asch, B. B. See Medina, Oborn, and Asch. 329 son, 1568 of Dextran-coated Charcoal and Sucrose Den Asch, B. B., Medina, D., Kretzer, F., Connolly, J. Adler, K. B. See Mossman, Ezerman. Adler, and sity Gradient Analyses of Estrogen and Proges L., and Brinkley, B. R. Comparative Responses Craighead, 4403 terone Receptors in Human Breast Cancer, of Normal and Malignant Mouse Mammary Cells Agarwal, R. P. See Walsh, Craig, and Agarwal. 4127 to Modulation of Surface Properties. 2383 3286 Anderson, L. W. See Danielson, Anderson, and Ashendel, C. L. See Verma. Ashendel. and Bou- Aglietta, M., Piacibello, W., and Gavosto, F. In- Hosick, 1812; Karle, Anderson, Erlichman, and twell. 308 sensitivity of Chronic Myeloid Leukemia Cells to Cysyk, 2938 Ashley, M. P. See Zbar, Canti, Rapp. Ashley, Inhibition of Growth by Prostaglandin E. 2507 Anderson, N. G. See Coggin, Adkinson. and An Sukumar, and Bast, 1036 Ahmed, N. K., and Baker, D. R. Properties of derson, 1568 Ashley, M. P., Zbar, B., Hunter, J. T., Rapp, H. Uridine-Cytidine Kinase Derived from L1210 Anderson, S. N. See Pauli, Anderson, Memoli. J., and Sugimoto, T. Adjuvant-Antigen Require Leukemia Cells. 3559 and Kuettner, 4571 ments for Active Specific Immunotherapy of Mi Akagi, H. See Wood, Levin, Chang, Huang, Ryan, Andrews, A. W. See Bigger. Tomaszewski, An croscopic MÃ©tastasesRemaining After Surgery, Thomas, Lehr, Kumar, Koreeda, Akagi, Utah, drews, and Dipple, 655 4197 Dansette, Yagi, Jerina, and Conney, 642 Andrews, J. P. See Blackburn, Andrews. Rao. Ashley, R. L., Cardiff, R. D., Mitchell, D. J., Akiyama, J. See Yamada, Kawamura, Gotohda. and Sorof, 4688 Faulkin, L. J., and Lund, J. K. Development Akiyama, Hosokawa, Kodama, and Kobayashi. Andrews, P. W. See Bronson, Andrews, Solter, and Characterization of Mouse Hyperplastic 954 Cervenka. Lange, and Fraley, 2500 Mammary Outgrowth Lines from BALB/cfC3H Albert, R. E. See McCormick, Burns, and Albert, Angeliis, D. See Chang, Ã•ngelus, and Fishman, Hyperplastic Alveolar Nodules, 4232 1140 1506 Assaf, A. See Janik. Assaf, and Bertram, 1950 Aldenderfer, P. See Waalkes. Abeloff, Woo, Ettin Anjo, T. See Mochizuki, Irving, Anjo. Wakabay- Asselin, J., Melancon, R., Moachon, G., and ger, Ruddon, and Aldenderfer, 4420 ashi, Suzuki, and Okada, 162 BÃ©langer,A. Characteristics of Binding to Es Alderson. P. See Order, Klein. Ettinger, Alderson, Animan, K. H. See Nadler. Stashenko. Hardy. trogen, Androgen, Progestin, and Glucocorti- Siegelman, and Leichner, 3001 ' Kaplan. Button. Kufe, Antman, and Schlossman, coid Receptors in 7,12-Dimethylbenz(a>- Alexander, J. A. See Wheeler, Alexander, and 3147 anthracene-induced Mammary Tumors and Adamson, 3723 Aoki, K. See Kimura, Taniguchi, Aoki, and Baba, Their Hormonal Control, 1612 Alexander, L. See Plunkett, Chubb, Alexander, 2061 Atryzek, V., Tamaoki, T., and Fausto, N. and Montgomery, 2349 Appella, E. See DuBois, Appella, Law, DeLeo, and Changes in Polysomal Polyadenylated RNA and Alexieva-Figusch, J. See Teulings, van Gilse, Old, 4204 a-Fetoprotein Messenger RNA during Hepato- Henkelman, Portengen, and Alexieva-Figusch, Appier, M. See Pallante, Fenselau, Mennel, Brun- carcinogenesis, 3713 2557 drett. Appier, Rosenshein, and Colvin. 2268 Atsumi, T. See Yoshida, Kiyohara, Fukui, Atsumi, All, M. K. See Wang, Madanat, Kimball, Gleiser, Aquino, J. See Ghose, Norvell, Aquino, Belitsky, Ogino, Inaba, Tsukagoshi, and Sakurai, 3810 Ali, Kaufman, and van Eys, 1022 Tai, Guclu. and Blair, 3018* Au, J. L-S-, and SadÃ©e,W. Activation of Ftorafur Allaben, W. T. See Beland, Allaben. and Evans, Arafah, B. M., Cullino, P. M., Manni, A., and [fl,S-1 -CTetrahydro-2-furanyl)-5-fluorouracil] to 5-Fluorouracil and y-Butyrolactone. 2814 Auda, S. P., Vuthiganon, C., and Elias, E. G. " August symposium issue, "Radioimmunodetection of Cancer" Effects of Different Shortwave Radiofrequencies

DECEMBER 1980 4839 Author Index to Volume 40

on Tumor Growth, 2829 Mosselmans, and Bannasch, 459 Uptake and Metabolism of Hexamethylmelam- Auerbach, R. See Morrissey, Sidky, and Auer- Barbin, A. See Zajdela, Croisy. Barbin, Malaveille, ine and Pentamethylmelamine by L5178Y Lym- bach, 2197 Tomatis, and Bartsch, 352 phoblasts in Vitro, 4489 Augusti-Tocco, G. See Vescia, Tramontano, Au Barlogie. B., Corry, P. M., and Drewinko, B. In Bekesi, J. G. See Chahinian, Beranek, Suzuki, gusti-Tocco, and D'Alessio, 3740 Vitro Thermochemotherapy of Human Colon Bekesi, Wisniewski, Selikoff, and Holland, 181 Aust, A. E., Falahee, K. J.. MÃ¤her, V. M., and Cancer Cells with c/s-Dichlorodiammineplati- Beland, F. A. See Morton, Beland, Evans, Fuller- McCormick, J. J. Human Cell-Mediated num(ll) and Mitomycin C, 1165 ton, and Kadlubar, 751 Benzo(a)pyrene Cytotoxicity and Mutagenicity Barlogie, B., and Drewinko, B. Lethal and Cyto- Beland, F. A., Allaben, W. T., and Evans, F. E. in Human Diploid Fibroblasts, 4070 kinetic Effects of Mitomycin C on Cultured Hu Acyltransferase-mediated Binding of N-Hydrox- Aylsworth, C. F., Sylvester, P. W., Leung, F. C., man Colon Cancer Cells, 1973 yarylamides to Nucleic Acids, 834 and Weites. J. Inhibition of Mammary Tumor Barrett, J. C. A Preneoplastic Stage in the Spon BÃ©langer,A. See Asselin, Melancon, Moachon, Growth by Dexamethasone in Rats in the Pres taneous Neoplastic Transformation of Syrian and BÃ©langer,1612 ence of High Serum Prolactin Levels, 1863 Hamster Embryo Cells in Culture, 91 Belch, A. See Brox, Gowans. and Belch, 1169 Barrett, J. C., Sheela. S., Ohki, K., and Kakun- Belitsky, P. See Ghose, Norvell, Aquino, Belitsky, aga, T. Reexamination of the Role of Plasmin- Tai, Guclu, and Blair, 3018' B ogen Activator Production for Growth in Semi- Bell, D. E. See Dow, Bell, Poulakos, and Fridland. solid Agar of Neoplastic Hamster Cells, 1438 1405 Baba, T. See Kimura, Taniguchi, Aoki, and Baba, Barrett, S. F. See Doniger, Barrett, and Robbins, Belman, S., and Garte, S. J. Antagonism between 2061 2736 Phorbol Myristate Acetate and Butyric Acid on Babcock, M. S. See Ohnuki. Mameli, Babcock, Bart, R. S., Porzio, N. R., Kopf, A. W., Vilcek, J. Isoproterenol Elevation of Cyclic Adenosine 3': Lechner, and Kaighn, 524 T., Cheng, E. H., and Parcel, Y. Inhibition of 5'-Monophosphate and their Effects on j8-Ad- Babiarz-Tracy, P., McCarthy, D., Simon, P., Bur- Growth of B16 Murine Malignant Melanoma by renergic Receptors in Mouse Epidermis, 240 lingham, W. J., and Fondy, T. P. Esters of Exogenous Interferon, 614 Bend, J. R. See Lee, Suzuki, Mukhtar, and Bend, Chlorohydroxyacetone in Chemotherapy of Mu Barthold, S. W., and Beck, D. Modification of 2486; Smith, Plummer, Ball, and Bend, 101 rine Tumors, 3274 Early Dimethylhydrazine Carcinogenesis by Co- Bender, R. A. See Jackson, Castle, Poplack, and Babonits, M. See Spira, Babonits, Wiener, Ohno, Ionic Mucosal Hyperplasia, 4451 Bender, 722 Wirschubski, Haran-Ghera, and Klein, 2609 Barton, R. A. See Jacobson, Levi, Juarez-Salinas, Benedict, W. F., Wheatley, W. L., and Jones, P. Bachur, N. R. See Egorin, Clawson, Cohen, Ross, Barton, and Jacobson. 1797 A. Inhibition of Chemically Induced Morpholog and Bachur, 4669; Egorin, Clawson, Ross, and Bartsch, H. See Sabadle. Malaveille. Camus, and ical Transformation and Reversion of the Trans Bachur, 1928 Bartsch, 119; Zajdela, Croisy, Barbin, Malav formed Phenotype by Ascorbic Acid in C3H/ 10T'/2 Cells, 2796 'â€¢ Backenstose, J. M. See MÃ¡rquez, Backenstose, eille, Tomatis, and Bartsch, 352 and Chapman, 713 Baserga, R. See Petralia, Soprano, Pochron, Dar- Benfield, J. R. See Shors, Fu, Matsumura, Cohen, Bagshawe. K. D., Searle, F., Lewis, J., Brown, zynkiewicz, TrÃ¡ganos, and Baserga, 3177 and Benfield, 2288 P., and Keep, P. Preliminary Therapeutic and Bashirelahi, N. See Bevins and Bashirelahi, 2234 Benjamin, R. S. See Ho, Carter, Brown, Hester, Localization Studies with Human Chorionic Go- Baskin, F. See Prashad, Rosenberg, Baskin, McCredie, Benjamin, Freireich, and Bodey, nadotrophin. 3016' Sparkman, Ulrich, and Wischmeyer, 2884 2441; Stewart, Benjamin, Leavens, Valdivieso, Bainton, D. F. See Dittman, Kramer, and Bainton, Bast, R. C., Jr. See Zbar, Canti, Rapp, Ashley. Burgess, and Bodey, 3750; Stewart, Leavens, 4473 Sukumar, and Bast, 1036 Friedman, Benjamin, Moore, Bodey, Valdivieso, Baird, W. M., Chemerys. R., Grinspan, J. B., Bateman. J. R. See Chan. Chlebowski, Tong. Burgess, Wiseman, and Loo. 3163 Mueller, S. N., and Levine, E. M. Chen, Gross, and Bateman, 1263 Bennett, J. A., and Marsh, J. C. Relationship of Bacillus Ca/meffe-Gue'r/n-induced Suppressor Benzo(a)pyrene Metabolism in Bovine Aortic Bathina, S. H. See DeWys and Bathina, 2202 Endothelial and Bovine Lung Fibroblast-like Cell Bauer, C. H., Buchsel, R., Morris, H. P., and Cells to Hematopoietic Precursor Cells, 80 Cultures, 1781 Reutter, W. G. Alterations of D-Galactose Me Bennett, S. J. See Goldenberg, Kim, DeLand, Baker, A. See Kreis, Baker, Ryan, and Bertasso, tabolism in Morris Hepatomas, 2026 Bennett, and Primus, 2984*; Kim, DeLand, Nel 634 Bauer, F. L. R. See Williamson, Bauer, Terpstra, son, Bennett, Simmons, Alpert, and Golden- Baker, D. R. See Ahmed and Baker, 3559 Ross, and Malt, 538 berg, 3008'; Pettit, DeLand, Bennett, and Gol- Baker, L. H. See Fraile, Baker. Buroker, Horwitz, Bauer, H. See Presek, Glossmann, Eigenbrodt, denberg, 3043'; Primus, Bennett, Kim, De- and Vaitkevicius, 2223 Schoner. RÃ¼bsamen,Friis, and Bauer, 1733 Land, Zahn, and Goldenberg, 497; van Nagell, Baker, M. A. See Shumak, Baker. Taub, Coleman, Baulieu, E-E. See Namer, Lalanne, and Baulieu, Kim, Casper, Primus. Bennett, DeLand, and and the Toronto Leukemia Study Group, 4048 1750 Goldenberg, 502 Baker, M. H. See Bryant. Jarman. Baker, Smith, Baumal, R., Marks, A., Mahony, J., and Bose, A. Beranek, J. T. See Chahinian, Beranek, Suzuki, and Smyth, 4734 Induction of Cytotoxic Factors by Immunization Bekesi, Wisniewski, Selikoff. and Holland, 181 Baker, N. See Kannan, Lyon, and Baker, 4606: of Mice with Freund's Adjuvant Components, Bergerat, J-P. See Stragand, Bergerat, White. Kannan, Ookhtens, and Baker, 2447 1630 Hokanson, and Drewinko, 2846 Baker, R. M. See Thompson, Baker, Carrano, and Baylin, S. B. See Gaidar, Carney, Russell, Sims, Bernacki, R. J. See Dobrossy, Pavelic, Vaughan, Brookman, 3245 Baylin, Bunn, Guccion, and Minna, 3502 Porter, and Bernacki, 3281 Bakir, N. A. See Thuning, Bakir, and Warren, Baylin, S. B., Abeloff, M. D., Goodwin, G., Car Bernaert, D. See Wanson, Bernaert, Penasse, 2726 ney, D. N., and Gazdar, A. F. Activities of L- Mosselmans, and Bannasch, 459 Baldini, M. G. See HarÃ¡, Steiner, and Baldini, Dopa Decarboxylase and Diamine Oxidase (His- Bernardis, L. L. See Ip, Yip, and Bernardis, 374 1212, 1217 taminase) in Human Lung Cancers and Decar Berry, D. E., and Collins, J. M. Neocarzinostatin- Bale, W. F., Contreras, M. A., and Grady, E. D. boxylase as a Marker for Small (Oat) Cell Can induced DNA Strand Scission and Subsequent Factors Influencing Localization of Labeled An cer in Cell Culture, 1990 Cell Cycle Traverse in HeLa S3 Cells, 2405 tibodies in Tumors, 2965* Beali, P. T. See Brinkley. Beali, Wible, Mace, Berry, D. L. See DiGiovanni. Berry, Gleason, Ki- Balinsky, D. See Cummins and Balinsky, 1235 Turner, and Cailleau, 3118 shore, and Slaga, 1580 Balis, M. E. See Wainfan, Brody, Relyea, and Beatile, C. W. See Chaudhuri, Walker, Beattie, Bertasso, A. See Kreis, Baker, Ryan, and Ber Balis. 620 and Das Gupta, 861 tasso, 634 Balis, M. E., Borenfreund, E., Brown, G. B., and Beck, D. See Barthold and Beck. 4451 Bertolini, L. See Fioritoni, Bertolini, Torlontano, Fox, J. J. Obituary: Aaron Bendich, 493 Beck, G. See DiStefano, Beck, Lysik, and Zucker, and Revoltella, 866 Balk, S. D., Hoon, B. S., King, G. M., Loskutoff. 1372 Bertram, J. S. Structure-Activity Relationships D., Mitchell, R. S., LeStourgeon, D. N., and Becker, F. F. See Stockert and Becker, 3632; among Various Retinoids and Their Ability to Weselake, R. J. Rapid, Reversible Rounding Stout and Becker, 1269; Stout, Hemminki, and Inhibit Neoplastic Transformation and to In and Aggregation of Rous Sarcoma Virus-in Becker, 3579 crease Cell Adhesion in the C3H/10T'A CL8 fected Chicken Fibroblasts Induced by a Plasma Becker, M. L. B. See Wilson, Becker, Hoal, and Cell Line, 3141. See also Janik, Assaf, and Macromolecule, 1753, Communication Dowdle, 933 Bertram, 1950 Ball, L. M. See Smith, Plummer, Ball, and Bend, Bedenko, V. See LaVoie, Hecht, Amin, Bedenko, Berzins, K. See Lando, Blomberg, Berzins, and 101 and Hoffmann, 4528 Perlmann, 1691 Banerjee, M. R. See Knauer, Iyer, Banerjee, and Beer, C. T. See Gout, Beer, and Noble, 2433; Besbris, H. J. See Wortzman, Besbris, and Cohen, Smith, 4368 Noble, Beer, and Gout, 2437 2670 Banerjee, S., Van Duuren, B. L., and Oruambo, Begg, A. C., Fu, K. K., Kane, L. J., and Phillips, Beversluis, M. See Scarpelli, Rao, Subbarao. Bev- F. I. Microsome-mediated Covalent Binding of T. L. Single-Agent Chemotherapy of a Solid ersluis, Gurka, and Hollenberg, 67 1,2-Dichloroethane to Lung Microsomal Protein Murine Tumor Assayed by Growth Delay and Bevins, C. L., and Bashirelahi, N. Stabilization of and Salmon Sperm DMA, 21 70 Cell Survival, 145 8S Progesterone Receptor from Human Pros Bannasch, P. See Wanson. Bernaert, Penasse, Begleiter, A., Grover, J., and Goldenberg, G. J. tate in the Presence of Molybdate Ion, 2234

4840 CANCER RESEARCH VOL. 40 Author Index to Volume 40

Bhatt, R. S. See Landolph, Bhatt, Telfer, and Burgess, Wiseman, and Loo. 3163 Parathyroid Hyperplasia Cells in Soft-Agar Cul Heidelberger, 4581 Boffa, L. C., Diwan, B. A., Gruss, R., and Allfrey, ture, 3694 Bhatt, T. S. See Coombs, Bhatt, Kissonerghis, V. G. Differences in Colonie Nuclear Proteins of Bradley, E. L., Jr. See Green. Pretlow, Tucker, and Vose, 882 Two Mouse Strains with Different Susceptibili Bradley, Cook, Pitts, and Pretlow, 1791 Bhuyan, B. K., Blowers, C. L., and Shugars, K. ties to 1,2-Dimethylhydrazine-induced Carcino Bradley, M. O., Sharkey, N. A., Kohn. K. W., and D. Lethality of Nogalamycin, Nogalamycin Ana genesis, 1774 Layard, M. W. Mutagenicity and Cytotoxicity of logs, and Adriamycin to Cells in Different Cell Bogyo, D., and Mihich, E. Reversal of the in Vitro Various Nitrosoureas in V-79 Chinese Hamster Cycle Phases, 3437 Methotrexate Suppression of Cell-mediated Im Cells, 2719 Bialkowski, S. See Pavelic, Dave, Bialkowski, Pri mune Response by Folinic Acid and Thymidine Bradwell. A. R. See HiÃ±e, Bradwell, Reeder. ore, and Greco, 4617 plus Hypoxanthine, 650 Droic, and Dykes, 2993' Biehl, J. See Payefte, Biehl, Toyama. Moltzer. and Bohoslawec, O. See Trown. Palleroni. Bohos- Brake, R. J. See Strniste, Martinez. Martinez, and Holtzer, 2465 lawec, Richelo, Halpern, Gizzi, Geiger, Lewin- Brake, 245 Bigger, C. A. H., Tomaszewski, J. E., Andrews, ski, Machlin, Jetten, and Jetten, 212 Brattain, M. G. See Kimball and Brattain, 1574 A. W., and Dipple, A. Evaluation of Metabolic Bohuon. C. See LaBrosse, Com-NouguÃ©,Zucker, Brattain, M. G.. Strobel-Stevens. J., Fine, D., Activation of 7,12-Dimethylbenz(a)anthracene Comoy, Bohuon, Lemerle, and Schweisguth, Webb, M., and Sarrif, A. M. Establishment of in Vitro by Aroclor 1254-induced Rat Liver S-9 1995 Mouse Colonie Carcinoma Cell Lines with Dif Fraction, 655 Boissard, C. See Laburthe, Roussel, Chevalier, ferent Metastatic Properties, 2142 Bigi, G. See Huber, Bigi, and Lucas, 3477, 3484 Boissard, Dupont, Zweibaum, and Rosselin, Braunschweiger, P. G., Schenken, L. L., and Binder, R. A. See Csako, Binder, Kales, and 2529 Schiffer, L. M. Adriamycin-induced Delayed Neefe, 3218 Bojko, C. See Platica, Bojko, and Hollander. 579; Erythropoietic Injury Expressed following Ane Blnggeli, R., and Cameron, I. L. Cellular Poten Platica, Bojko. Steiner, and Hollander, 2229 mia Stress, 2257 tials of Normal and Cancerous Fibroblasts and Bolanowska, W. See Gurtoo, Vaught, Mannello, Braunschweiger, P. G., and Schiffer, L. M. Cell Hepatocytes, 1830 Paigen, Gessner, and Bolanowska, 1305 Kinetic-directed Sequential Chemotherapy with Birnbaum, R. S., Muszynski, M., and Roos, B. A. Bom-van Noorloos, A. A., van Beek, A. A. M., Cyclophosphamide and Adriamycin in T1699 Tumor and Plasma Somatostatin-like Immuno- and Melief, C. J. M. Cryopreservation of Cells Mammary Tumors, 737 for Immunological Typing of Non-Hodgkin's reactivity in Transplantable Rat Medullary Thy Braylan, R. C. See Diamond and Braylan, 703 roid Carcinoma, 4192 Lymphomas, 2890 Breed, J. G. S., Zimmerman, A. N. E., Dormans, Bishop, W. W. See Skipper, Tannenbaum, Thilly, Bonar, R. A. See Shrivastav, Bonar, Stone, and J. A. M. A., and Pinedo, H. M. Failure of the Furth, and Bishop, 4704 Paulson, 4438; Shrivastav, Stone, Paulson, and Antioxidant Vitamin E to Protect against Adria Bize, I. B., Oberley, L. W., and Morris, H. P. Bonar, 4443 mycin-induced Cardiotoxicity in the Rabbit, Superoxide Dismutase and Superoxide Radical Bondi, E. See Herlyn, Clark, Mastrangelo, Guerry. 2033 in Morris Hepatomas, 3686 Elder, LaRossa, Hamilton. Bondi. Tuthill, Ste- Breimer, M. E. Adaptation of Mass Spectrometry Black, M. M., and Zachrau, R. E. Correspondence plewski, and Koprowski, 3602 for the Analysis of Tumor Antigens as Applied re: H. J. Rapp and H. B. Hewitt. Appropriateness Boniver, J., DeclÃ¨ve, A., Finn, 0. J., Honsik, C., to Blood Group Glycolipids of a Human Gastric of Animal Models for the Immunology of Human Lieberman, M., and Kaplan, H. S. Detection of Carcinoma. 897 Cancer. Cancer Res., 39. 4285-4287, 1979, Infectious Centers in C57BL/Ka Lymphoid Cell Brennan, M. F. See Bradley, Reichert, Brennan, page 492, Letter to the Editor Populations Infected in Vitro by the Radiation and Von Hoff, 3694; Speyer, Collins, Dedrick, Black, P. H. See Schroder, Chou, and Black, Leukemia Virus. 544 Brennan, Buckpitt, Londer. DeVita, and Myers. 3089 Bonomi, P. See Anderson, Bonomi. Marogil. Hen- 567 Blackburn, G. R., Andrews, J. P., Rao, K. V. K., drickson, and Economou. 4127 Brennessel, B. A. See Gottlieb. Chang, Buhrer, and Sorof, S. An Early Event Associated with Boot, L. M. Obituary: Otto F. E. MÃ¼hlbock,190 and Brennessel, 758 Liver Carcinogenesis Involving Loss of a Poly- Bootsma, D. See Hashem, Bootsma, Keijzer, BrÃ©sil,H. See Montesano, BrÃ©sil,Planche-Martel, peptide that Binds Carcinogen, 4688 Greene, Coriell, Thomas, and Cleaver, 13 Margison, and Pegg. 452 Blackman, K. E. See Szakal, Diwan, and Black- Bordelon-Riser, M. E. See Siciliano, Bordelon- Bresnick, E. See Heintz, Little, Bresnick. and man, 2475 Riser, Freedman, and Kohler, 283 Schaeffer, 1281 Blackwell, B. N. See Lijinsky, Saavedra, Reuber, Boreiko, C., Mondai, S., Narayan, K. S., and Brinkley, B. R. See Asch, Medina, Kretzer, Con and Blackwell, 3325 Heidelberger, C. Effect of 12-O-Tetradecanoyl- nolly, and Brinkley. 2383 Blair, A. H. See Ghose, Norvell, Aquino, Belitsky, phorbol-13-acetate on the Morphology and Brinkley, B. R., Beali, P. T., Wible, L. J., Mace, Tai, Guclu, and Blair, 3018* Growth of C3H/10T'Â¿ Mouse Embryo Cells, M. L., Turner, D. S., and Cailleau, R. M. Varia Bleyer, W. A. See Bode, Manrnth, Bleyer, Po 4709 tions in Cell Form and Cytoskeleton in Human plack, and Glaubiger, 2184 Borenfreund, E. See Balis, Borenfreund, Brown, Breast Carcinoma Cells in Vitro, 3118 Bloch, A. See Kinahan, Pavelic, Leonard, Bloch, and Fox, 493 Brockman, R. W., Cheng, Y-C., Schabel, F. M., and Grindey, 598 Boritzki, T. J. See Jackson. Lui. Boritzki, Morris, Jr., and Montgomery, J. A. Metabolism and Blomberg, F. See Lando, Blomberg, Berzins. and and Weber, 1286 Chemotherapeutic Activity of 9-/3-o-Arabinofur- Perlmann, 1691 Borresen, T., Henriksen, 0. B., and Christensen, anosyl-2-fluoroadenine against Murine Leuke Bloom, J. C., Ganjam, V. K., and Gabuzda, T. G. N. J. Decreased Norepinephrine Concentration mia L1210 and Evidence for Its Phosphorylation Glucocorticoid Receptors in Peripheral Blood in Normal Tissue Neighboring a Malignant Tu by Deoxycytidine Kinase, 3610 Lymphocytes from Bovine Leukemia Virus-in mor, 4320, Communication Brody, H. See Wainfan, Brody. Relyea. and Balis, fected Cows with Persistent Lymphocytosis, BÃ¶rzsÃ¶nyi,M., TÃ¶rÃ¶k,G., Pinter, A., Surjan, A., 620 2240 NÃ¡dasdi, L., and Roller, P. Carcinogenic Effect Brogger. A. See Tveit. Fodstad. Bregger, and Blot, W. J. See Tagnon, Blot, Stroube, Day, Mor of Dinitrosopiperazine in Adult Swiss Mice and Olsnes, 949 ris, Peace, and Fraumeni, 3875 after Transplacent.il or Translactational Expo Bronson. D. L. See Wang, Trend, Bronson, and Blowers, C. L. See Bhuyan, Blowers, and Shu- sure, 2925 Fraley, 796 gars, 3437 Bose, A. See Baumal, Marks, Mahony, and Bose. Bronson, D. L., Andrews, P. W., Solter, D., Cer- Blumberg, P. M. See Driedger and Blumberg, 1630 venka, J., Lange, P. H., and Fraley, E. E. Cell 339, 1400; Dunphy, Delclos, and Blumberg, Bosmann, H. B. See Evans, Hilf, Murphy, and Line Derived from a Metastasis of a Human 3635; Nagle and Blumberg, 1066 Bosmann. 3103 Testicular Germ Cell Tumor. 2500 Blumenstein, B. A. See Kann, Blumenstein, Pet- Boss, G. R. See Howell, Herbst, Boss, and Frei, Brookman, K. W. See Thompson, Baker, Carrano. kas, and Schott. 771 1824 and Brookman, 3245 Blumer, J. L., Friedman, A., Meyer, L. W., Fair- Bout well, R. K. See Perchellet and Boutwell, Brooks, S. C., Jr. See Everson, Lippman, Thomp child, E., Webster, L. T., Jr., and Speck, W. T. 2653; Verma, Ashendel, and Boutwell, 308; son, McGuire, Wittliff. De Sombre, Jensen, Sin- Relative Importance of Bacterial and Mammalian Verma, Slaga, Wertz, Mueller, and Boutwell, ghakowinta, Brooks, and Neifeld, 991 Nitroreductases for Niridazole Mutagenesis, 2367; Weekes, Verma, and Boutwell, 4013 Brooks, T. L. See Green, Brooks, Mendelsohn, 4599 Boyd, A. L. See Hampar, Boyd, Derge, Zweig, and Howell, 535 Bode, U., Magrath, I. T., Bleyer, W. A., Poplack, Eader, and Showalter, 2213 Brouwer, J. See Herbrink, Moen, Brouwer, and D. G., and Glaubiger, D. L. Active Transport of Boynton, A. L., and Whitfield, J. F. Stimulation of Warnaar, 166 Methotrexate from Cerebrospinal Fluid in Hu DNA Synthesis in Calcium-deprived, T51B Liver Brown, C. K. See Welsch, Brown, Goodrich- mans, 2184 Cells by the Tumor Promoters PhÃ©nobarbital, Smith, Chiusane, and Moon, 3095 Bodey, G. P. See Ho. Carter, Brown, Hester. Saccharin, and TPA, 4541 Brown, G. B. See Balis, Borenfreund, Brown, and McCredie, Benjamin. Freireich, and Bodey, Bradley, E. See Von Hoff, Casper, Bradley, Trent. Fox, 493 2441; Stewart, Benjamin, Leavens, Valdivieso, Hodach, Reichert, Makuch, and Altman, 3591 Brown, J. M. See Catapano, Brown, and Rosen Burgess, and Bodey, 3750; Stewart, Leavens, Bradley, E. C., Reichert, C. M., Brennan, M. F., berg, 979 Friedman, Benjamin, Moore. Bodey, Valdivieso, and Von Hoff, D. D. Direct Cloning of Human Brown, N. S. See Ho, Carter. Brown, Hester,

DECEMBER 1980 4841 Author Index to Volume 40

McCredie, Benjamin, Freireich, and Bodey, Burns, E. R. See Scheving. Burns, Pauly, and sell, Sims, Baylin, Bunn. Guccion, and Minna, 2441 Halberg, 1511 3502 Brown, P. See Bagshawe, Searle, Lewis, Brown, Burns, F. J. See McCormick, Burns, and Albert, Carney, D. N., Gazdar, A. F., and Minna, J. D. and Keep, 3016' 1140 Positive Correlation between Histological Tumor Brox, L. W., Gowans, B., and Belch, A. L-Phen- Buroker, T. R. See Fraile, Baker, Buroker, Hor- Involvement and Generation of Tumor Cell Col ylalanine Mustard (Molphalan) Uptake and witz, and Vaitkevicius, 2223 onies in Agarose in Specimens Taken Directly Cross-Linking in the RPMI 6410 Human Lym- Busbee, D. L. See Rankin, Jacobson, Mitchell, from Patients with Small-Cell Carcinoma of the phoblastoid Cell Line, 1169 and Busbee, 1803 Lung, 1820 Broxmeyer, H. E. See Pelus, Broxmeyer, Clark- Busby, W. F., Jr. See Groopman, Busby, and Carpentieri, U., Minguen, J. J., and Haggard, M. son, and Moore. 2512 Wogan, 4343 E. Variation of Activity of Protein Kinases in Broxmeyer, H. E., Ralph, P., Gilbertson, S., and Busch, H. See Chan, Feyerabend, Busch, and Unstimulated and Phytohemagglutinin-stimu- Margolis, V. B. Induction of Leukemia-Associ Busch, 3194; Raju, Morris, and Busch, 1623; lated Normal and Leukemic Human Lympho ated Inhibitory Activity and Bone Marrow Gran- Reiners, Davis, and Busch, 1367 cytes, 2714 ulocyte-Macrophage Progenitor Cell Alterations Busch, R. K. See Chan, Feyerabend, Busch, and Carpentieri, U., and Sordahl, L. A. Respiratory during Infection with Abelson Virus, 3928 Busch, 3194 and Calcium Transport Functions of Mitochon Brunda, M. J., Mathews, H. L., Ferguson, H. R., Butel, J. S. See Medina, Butel, Socher, and Miller, dria Isolated from Normal and Transformed Hu McClatchy, J. K., and Minden, P. Immunother- 368 man Lymphocytes, 221 apy of the Guinea Pig Line 10 Hepatocarcinoma Button, L. N. See Nadler, Stashenko, Hardy, Ka Carpinelli, A. R. See Malaisse, Sener, Herchuelz. with a Variety of Nonviable Bacteria, 3211 plan, Button, Kufe, Antman. and Schlossman, Carpinelli, Poloczek, Winand. and Castagna, Brundrett, R. B. See Pallante, Fenselau, Mennel, 3147 3827 Brundrett, Appier, Rosenshein, and Colvin, Bynum, J. W. Characterization of Adenosine-in- Carrano, A. V. See Thompson, Baker. Carrano, 2268 duced Cytostasis in Melanoma Cells, 2147 and Brookman, 3245 Brunengraber, H. See Essigmann, Donahue, Carraway, K. L. See Huggins, Trenbeath, Sher- Story, Wogan, and Brunengraber, 4085 blom, Howard, and Carraway, 1873 Brunei, M. See PichÃ³n, Pallud, Brunei, and Mil- Carrel, S., Accolla, R. S., Carmagnola, A. L., and grom, 3357 Mach, J-P. Common Human Melanoma-associ Brunke, K. J., Strickler, G., and Leboy, P. S. ated Antigen(s) Detected by Monoclonal Anti Elevated Methylation Capacity of Selected Cabot, M. C., Welsh, C. J., Callaham, M. F., and bodies, 2523 Transfer RNA Methyltransferases from 9,10-Di- Huberman, E. Alterations in Lipid Metabolism Carrell, H. L. See Rossi, Cantrell, Farber, Dyott, methyl-1,2-benzanthracene-induced Rat Mam Induced by 12-O-Tetradecanoylphorbol-13- Carrell. and Glusker. 2774 mary Tumors, 417 acetate in Differentiating Human Myeloid Leu Carrico, C. K. See Ardalan, Cooney, Jayaram, Bruszewski, J. A. See Long, Bruszewski, and kemia Cells, 3674 Carrico, Glazer, Macdonald, and Schein, 1431 Snead, 22 Cabrai, J. R. P. See Neal and Cabrai. 4739 Carson, D. A. See Kamatani and Carson, 4178 Bryan, A. H. See Ruddon, Bryan, Meade-Cobun, Cacheiro, L. H. See Perkins and Cacheiro. 357 Carter, C. J. See Ho, Carter, Brown, Hester, and Pollack, 4007 Cadman, E. See Grant and Cadman, 4000; Grant, McCredie, Benjamin. Freireich, and Bodey. Bryan, G. T. See Matsushima and Bryan, 1897; Lehman, and Cadman, 1525 2441 Pamukcu, Yalciner, Hatcher, and Bryan, 3468; Cailleau, R. M. See Brinkley, Beali, Wible, Mace, Caruana, J. See Greenberg, Caruana, Holcomb. Rose, Pruitt, Stauber, ErtÃ¼rk,and Bryan, 235 Turner, and Cailleau, 3118 Greenberg, Parker, Louis, and White, 439 Bryant, B. M., Jarman, M., Baker, M. H., Smith, Calderwood, S. K., and Dickson, J. A. Effect of Casper, J. See Von Hoff, Casper, Bradley, Trent, I. E., and Smyth, J. F. Quantification by Gas Hyperglycemia on Blood Flow, pH, and Re Hodach, Reichert, Makuch, and Altman, 3591 Chromatography of W,W-di-<2-Chloroethyl>- sponse to Hyperthermia (42Â°C) of the Yoshida Casper, S. See van Nagell, Kim, Casper, Primus, phosphorodiamidic Acid (Isophosphoramide Sarcoma in the Rat. 4728 Bennett, DeLand, and Goldenberg, 502 Mustard) in the Plasma of Patients Receiving Callaham, M. F. See Cabot, Welsh, Callaham, and Castagna, M. See Malaisse, Sener, Herchuelz, Isophosphamide, 4734 Huberman, 3674 Carpinelli, Poloczek, Winand, and Castagna, Bryant, D., Smith, R., Sharma, S., and Dodge, Calvert, I. See Rosen, Calvert, Weintraub, Tseng, 3827 W. Some Circulating Factors which Influence and Rabson. 4325 Castle, M. C. See Jackson, Castle, Poplack, and Granulocyte/Monocyte Production in the Chick Cameron, I. L. See Binggeli and Cameron, 1830 Bender, 722 with Myeloblastic Leukemia, 4031 Cameron, I. L., Smith, N. K. R., Pool, T. B., and Castronovo, F. P., Jr., Potsaid. M. S., and Kopi- Bucana, C. D. See Raz, MeLellan, Hart, Bucana, Sparks, R. L. Intracellular Concentration of So woda, S. Formulation and Biological Distribution Hoyer, Sela, Dragsten, and Fidler, 1645 dium and Other Elements as Related to Mito- of Radiolabeled 1-<2-Chloroethyl)-3-cyclohexyl- Buchsei, R. See Bauer, Buchsei, Morris, and genesis and Oncogenesis in Vivo, 1493 1-nitrosourea in an Animal Tumor Model, 3473 Reutter, 2026 Camiolo, S. M. See Markus. Takita, Camiolo, Cor Catane, R. See Clement, Gorman, Wodinsky, Ca Buckpitt, A. R. See Speyer. Collins, Oedrick, asanti, Evers, and Hobika, 841 tane, and Johnson, 4165 Brennan, Buckpitt, Londer, DeVita, and Myers, Campbell, H. A. See Pilot, Goldsworthy, Camp Catapano, M. S., Brown, J. M., and Rosenberg, 567 bell, and Poland, 3616 S. A. Levels of Cytotoxic Reactivity to Cultured Buening, M. K., Levin, W., Wood, A. W., Chang, Camus, A-M. See Sabadle, Malaveille, Camus, Normal Skin Fibroblasts in Sera from Normal R. L., Lehr, R. E., Taylor, C. W., Vagi, H., and Bartsch, 119 and Sarcoma-bearing Patients, 979 Jerina, D. M., and Conney, A. H. Tumorigenic Canellos, G. P. See Lampidis, Henderson, Israel, Cavallo, G. See Giovarelli, Padula, Ugazio. Forni, Activity of Benzo(e)pyrene Derivatives on and Canellos, 3901 and Cavallo, 3745 Mouse Skin and in Newborn Mice, 203 Cannon, G. See Stern, Wilczek, Thorpe, Rosen Cayama, E. See Solt, Cayama, Sarma, and Far Buesa-Perez, J. M., Leyva, A., and Pinedo, H. M. berg, and Cannon, 325 ber, 1112 Effect of Methotrexate on 5-Phosphoribosyl 1- Canti, G. See Zbar, Canti, Rapp, Ashley, Suku- Cederbaum, A. I. See Sun and Cederbaum, 4677 Pyrophosphate Levels in L1210 Leukemia Cells mar, and Bast, 1036 Cerny, W. L. See Mehta, Cerny. and Moon, 47 in Vitro, 139 Cantor, K. P., and Fraumeni, J. F., Jr. Distribution Cerutti, P. A. See Kaneko and Cerutti, 4313; Bugelski, P. See Fidler, Raz, Fogler, Kirsh, Bug- of Non-Hodgkin's Lymphoma in the United Wang and Cerutti, 2904 elski, and Poste, 4460 States between 1950 and 1975, page 2645 Cervenka, J. See Bronson, Andrews, Bolter, Cer- Buhrer, D. P. See Gottlieb, Chang, Buhrer, and Cantrell, J. S. See Rossi, Cantrell, Farber, Dyott, venka. Lange, and Fraley, 2500 Brennessel, 758 Carrell, and Glusker, 2774 Chabner, B. A. See Erlichman, Strong, and Chab- Bullock, B. C. See McLachlan, Newbold, and Carchman, R. A. See Laskin, Laskin, Weinstein, ner, 1902 Bullock, 3988 and Carchman, 1028; White. Carchman, Fry, Chahinian, A. P., Beranek, J. T., Suzuki, Y., Bunn, P. A., Jr. See Gazdar, Carney, Russell, and Goldman, 2400 Bekesi, J. G., Wisniewski, L., Selikoff, I. J., Sims, Baylin, Bunn, Guccion, and Minna, 3502 Cardiff, R. D. See Ashley, Cardiff, Mitchell, and Holland, J. F. Transplantation of Human Burchenal, D. See Murgo, Fried, Burchenal, Vale, Faulkin, and Lund, 4232; Drohan, Cardiff, Lund, Malignant Mesothelioma into Nude Mice, 181, Strife, Woodcock, Young, and Clarkson, 1543 and Schlom, 2316 Communication Burchenal, J. H. See Woodcock. Chou. Tan, Cardy, R. H., and Lijinsky, W. Comparison of the Chalvet, O. See Perin-Roussel, Croisy-Delcey, Sternberg, Philips. Young, and Burchenal, 4243 Carcinogenic Effects of Five Nitrosamines in Mispelter, Saguem, Chalvet, Ekert, Fouquet, Burger, M. M. See Finne, Tao, and Burger, 2580 Guinea Pigs, 1879 Jacquignon, Lhoste, Muel, and Zajdela, 1742 Burgess, M. A. See Stewart, Benjamin, Leavens, Carmagnola, A. L. See Carrel, Accolla, Carmag Chan, K. K., Chlebowski, R. T., Tong, M., Chen, Valdivieso, Burgess, and Bodey, 3750; Stewart, nola, and Mach, 2523 H-S. G., Gross, J. F., and Bateman, J. R. Clin Leavens. Friedman, Benjamin, Moore, Bodey. Carmignani, M. See Ranelletti, lacobelli, Carmig- ical Pharmacokinetics of Adriamycin in Hepa- Valdivieso, Burgess, Wiseman, and Loo. 3163 nani, Sica. Natoli, and Tonali, 2020 toma Patients with Cirrhosis, 1263 Burlingham, W. J. See Babiarz-Tracy, McCarthy, Carney, D. N. See Baylin, Abeloff, Goodwin, Car Chan, P-K., Feyerabend, A., Busch, R. K., and Simon, Burlingham, and Fondy, 3274 ney, and Gazdar, 1990; Gazdar, Carney, Rus Busch, H. Identification and Partial Purification

4842 CANCER RESEARCH VOL. 40 Author Index to Volume 40

of Human Tumor Nucleolar Antigen 54/6.3, and Edwards, L. Clinical Phase l-ll and Phar- 2670 page 3194 macokinetic Study of High-Dose Thymidine Cohen, B. I. See Raicht, Cohen, Fazzini, Sarwal, Chan, V-L. See Juranka and Chan, 4123 Given by Continuous Intravenous Infusion, 818 and Takahashi, 403 Chang, B. K., Huang, A. T., and Joines, W. T. Chlebowski, R. T. See Chan. Chlebowski. Tong, Cohen, G. M., MacLeod, M. C., Moore, C. J., and Inhibition of DMA Synthesis and Enhancement Chen, Gross, and Bateman, 1263 Selkirk, J. K. Metabolism and Macromolecular of the Uptake and Action of Methotrexate by Chong, M. T., and Lippman, M. Purification of Binding of Carcinogenic and Noncarcinogenic Low-Power-Density Microwave Radiation in Estrogen Receptors from MCF-7 Human Breast Metabolites of Benzo(a)pyrene by Hamster Em L1210 Leukemia Cells, 1002 Cancer Cells, 3172 bryo Cells, 207 Chang, C. H., Angelus, O., and Fishman, W. H. Chou, I-N. See Schroder, Chou, and Black, 3089 Cohen, J. L. See Egorin. Clawson, Cohen, Ross, Presence of the Rare D-Variant Heat-stable, Chou, J. Y. Effects of Adenosine Cyclic Nucleo- and Bachur, 4669 Placental-type Alkaline Phosphatase in Normal tides on the Synthesis of Human Chorionic Go- Cohen, S. M. See Fukushima and Cohen, 734 Human Testis, 1506 nadotropin in Transformed Human Placental Cole, C. F. See Estensen, DeHoogh, and Cole, Chang, C-H., and Cheng, Y-C. Effects of Deoxy- Cells, 4025 1119 adenosine Triphosphate and 9-/3-o-Arabinofu- Chou, M. W. See Wislocki, Gadek, Chou, Yang, Coleman, M. S. See Shumak, Baker, Taub, Cole- ranosyladenine S'-Triphosphate on Human Ri- and Lu, 3661 man, and the Toronto Leukemia Study Group, bonucleotide ReducÃasefrom Molt-4F Cells and Chou, T-C. See Warrell, Chou, Gordon, Tan, Rob 4048 the Concept of "Self-Potentiation," 3555 erts, Sternberg, Philips, and Young, 4546; Colletta, G., Di Fiore, P. P., Ferrentino, M., Pie- Chang, J. See Gottlieb, Chang, Buhrer, and Bren Woodcock, Chou, Tan, Sternberg, Philips, tropaolo, C., Turco, M. C., and Vecchio, G. nessel, 758 Young, and Burchenal, 4243 Enhancement of Viral Gene Expression in Chang, R. L. See Buening, Levin, Wood, Chang, Chou, T-H. See Kessel, Shah-Roddy. Mirchan- Friend Erythroleukemic Cells by 12-O-Tetra- Lehr, Taylor, Yagi, Jerina, and Conney. 203; dani, Khilanani, and Chou, 3576 decanoylphorbol-13-acetate, 3369 Levin, Wood, Chang, Ittah, Croisy-Delcey, Yagi, Christensen, E. I. See Reddy, Rao, Warren, Qur- Collette, J. See Santen, Collette, and Franchi- Jerina, and Conney, 3910; Wood, Chang, eshi, and Christensen, 3443 moni. 1181 Huang, Levin, Lehr, Kumar, Thakker, Yagi, Jer Christensen, I. J. See Vindelov, Hansen. Chris Collier, A. M. See Vesterinen, Nedrud, Collier, ina, and Conney, 1985; Wood, Chang, Levin, tensen, Spang-Thomsen, Hirsch, Hansen, and Walton, and Pagano, 512 Ryan, Thomas, Croisy-Delcey, Ittah, Yagi, Jer Nissen. 4295 Collier, R. J. See Gilliland and Collier, 3564 ina, and Conney, 2876; Wood, Levin, Chang, Christensen, N. J. See Borresen, Henriksen, and Collins, J. J., and Snyderman, R. Absence of Huang, Ryan, Thomas, Lehr, Kumar, Koreeda, Christensen. 4320 Macrophage Involvement in the Passive SÃ©rum Akagi, Ittah, Dansette, Yagi. Jerina, and Con Christensen, T. See Moan, Waksvik, and Chris Therapy of Friend Leukemia Virus-induced Dis ney, 642 tensen, 2915 ease, 557 Chao, M. See Rutzky. Kaye. Siciliano, Chao, and Christensen, W. L. See Long, Suk, Snead, and Collins, J. M. See Berry and Collins, 2405 Kahan, 1443 Christensen, 3886 Collins, J. M. See Speyer, Collins, Dedrick, Bren- Chapman, J. L. See MÃ¡rquez, Backenstose, and Christman, J. K. See Mendelsohn, Gilbert, Christ- nan, Buckpitt, Londer, DeVita, and Myers. 567 Chapman, 713 man, and Acs, 1469; Mendelsohn, Michl, Gil Colombies, P. See Kessous, Colombies, Pris, and Chase, E. S. See Shafer and Chase, 3186 bert, Acs, and Christman, 3206 Clement, 1354 Chaudhuri, P. K., Walker, M. J., Beattie, C. W., Chu, T. M. See Kuriyama, Wang, Papsidero, Kil- Coltman, C. A., Jr. See Von Hoff, Pollard, KÃ¼hn, and Das Gupta, T. K. Presence of Steroid Re lian, Shimano, Valenzuela, Nishiura, Murphy, Murray, and Coltman, 1516 ceptors in Human Soft Tissue Sarcomas of Di and Chu, 4658; Lee, Murphy, and Chu, 1245; Colvin, M. See Pallante, Fenselau, Mennel, Brun- verse Histological Origin, 861 Papsidero, Wang, Valenzuela, Murphy, and drett. Appier, Rosenshein, and Colvin, 2268; Chawla, R. K., Lawson, O. H., Richmond, A., and Chu, 2428; Papsidero, Wojcieszyn, Horoszew- Redwood and Colvin, 1144 Rudman, D. Effect of Plasma Inter-Alpha Tryp- icz, Leong, Murphy, and Chu, 3032' Com-Nougue, C. See LaBrosse, Com-Nougue, sin Inhibitor and Cancer-related Glycoprotein Chubb, S. See Plunkett, Chubb, Alexander, and Zucker, Comoy, Bohuon, Lemerle, and EDC1 on Phytohemagglutinin-induced Thymi- Montgomery. 2349; Plunkett, Hug. Keating, and Schweisguth, 1995 dine Uptake in Lymphocytes, 4187 Chubb, 588 Comoy, E. See LaBrosse, Com-NouguÃ©.Zucker, Chawla, R. K., Shlaer, S. M., Lawson, D. H., Cimino, J. S. See Sutherland, Cimino, Delihas, Comoy, Bohuon, Lemerle, and Schweisguth, Murray, T. G., Schmidt, F., Shoji, M., Nixon, Shih, and Oliver, 1934 1995 D. W., Richmond, A., and Rudman, D. Elevated Clark, W. H., Jr. See Herlyn, Clark, Mastrangelo, Conanan, L. B. See Crutchley, Conanan. and Plasma and Urinary Guanosine 3':5'-Mono- Guerry. Elder, LaRossa, Hamilton, Bondi, Tut- Maynard, 849 phosphate and Increased Production Rate in hill, Steplewski, and Koprowski, 3602 Conley, F. K. Influence of Chronic Toxoplasma Patients with Neoplastic Diseases, 3915 Clarke, A. See Gilman, Docherty, Clarke, and Infection on Ethylnitrosourea-induced Central Check, I. J., Hunter, R. L., Rosenberg, K. D., and Rawls. 4640 Nervous System Tumors in Rats, 1240 Herbst, A. L. Prediction of Survival in Gyneco Clarke, F. M. See Hard, Clarke, and Ton. 3728 Conney, A. H. See Buening, Levin, Wood, Chang, logical Cancer Based on Immunological Tests, Clarkson, B. D. See Arlin, Sklaroff, Gee, Kempin. Lehr, Taylor, Yagi, Jerina, and Conney, 203; 4612 Howard, Clarkson, and Young, 3304; Murgo, Levin, Wood, Chang, Ittah, Croisy-Delcey, Yagi, Cheever, M. A. See Greenberg, Cheever, and Fried, Burchenal, Vale, Strife, Woodcock, Jerina. and Conney, 3910; Wood, Chang, Fefer, 4428 Young, and Clarkson. 1543; Pelus, Broxmeyer, Huang. Levin, Lehr, Kumar, Thakker, Yagi, Jer Chemerys, R. See Baird, Chemerys, Grinspan, Clarkson, and Moore, 2512 ina, and Conney, 1985; Wood. Chang. Levin, Mueller, and Levine, 1781 Clawson, G. A., Koplitz, M., Moody, D. E., and Ryan, Thomas, Croisy-Delcey, Ittah, Yagi, Jer Chen, C-h. B. See Hecht, Chen, Ohmori, and Smuckler, E. A. Effects of Thioacetamide Treat ina, and Conney, 2876; Wood, Levin. Chang, Hoffmann, 298; Hecht, Young, and Chen, 4144 ment on Nuclear Envelope Nucleoside Triphos- Huang, Ryan, Thomas, Lehr, Kumar, Koreeda, Chen, H-S. G. See Chan, Chlebowski, Tong, phatase Activity and Transport of RNA from Rat Akagi, Ittah. Dansette, Yagi. Jerina, and Con Chen, Gross, and Bateman, 1263 Liver Nuclei, 75 ney, 642 Chen, K. Y. See Liu, Fiske, and Chen, 4100 Clawson, R. E. See Egorin, Clawson, Cohen, Connolly, J. L. See Asch, Medina, Kretzer, Con Cheng, C. Y. See Howard, Cheng, and Howard, Ross, and Bachur. 4669; Egorin, Clawson, nolly, and Brinkley, 2383 4385 Ross, and Bachur, 1928 Connor, M. See Newberne and Connor, 4037 Cheng, E. H. See Bart, Porzio, Kopf, Vilcek. Cleaver, J. E. See Hashem, Bootsma. Keijzer, Contreras, M. A. See Bale, Contreras, and Grady, Cheng, and Parcel, 614 Greene, Coriell, Thomas, and Cleaver, 13 2965' Cheng, Y-C. See Brockman, Cheng, Schabel, and Clement, D. See Kessous, Colombies, Pris, and Cook, M. G., and McNamura, P. Effect of Dietary Montgomery, 3610; Chang and Cheng. 3555 Clement, 1354 Vitamin E on Dimethylhydrazine-induced Co- Cheshire, L. B. See Peterson. Varakis. and Clement, J. J., Gorman, M. S., Wodinsky, I., Ionic Tumors in Mice. 1329 Cheshire, 3130 Catane, R., and Johnson, R. K. Enhancement Cook, W. J. See Green, Pretlow, Tucker, Bradley, Chevalier, G. See Laburthe, Roussel, Chevalier, of Antitumor Activity of Alkylating Agents by the Cook, Pitts, and Pretlow, 1791 Boissard, Dupont, Zweibaum, and Rosselin, Radiation Sensitizer Misonidazole. 4165 Coombs, M. M., Bhatt, T. S., Kissonerghis, A-M., 2529 Coccia, J. B. See Wattenberg, Coccia, and Lam. and Vose, C. W. Mutagenic and Carcinogenic Chirigos, M. A., and Stylos, W. A. Immuno- 2820 Metabolites of the Carcinogen 15.16-Dihydro- modulatory Effect of Various Molecular-Weight Coggin, J. H., Jr. See Weppner and Coggin, 1380 11-methylcyclopenta[a]phenanthren-17-one, Maleic Anhydride-Divinyl Ethers and Other Coggin, J. H., Jr., Adkinson, L., and Anderson, 882 Agents in Vivo, 1967 N. G. Fetal Antigens Shared as Transplantation Cooney, D. A. See Ardalan. Cooney. Jayaram, ChiÃ¹, H. C. See Yoo, ChiÃ¹,Spector, Whiteaker, Rejection Antigens on Chemically-induced Carrico, Glazer, Macdonald, and Schein, 1431; Denning, and Lee, 1084 Mouse and Hamster Sarcomas, 1568 Tyagi and Cooney, 4390 Chiusano, J. See Welsch, Brown, Goodrich- Cohen, A. H. See Shors, Fu, Matsumura. Cohen, Corasanti, J. G. See Markus, Takita, Camiolo, Smith, Chiusano, and Moon, 3095 and Benfield, 2288 Corasanti, Evers, and Hobika, 841 Chiuten, D. F., Wiernik, P. H., Zaharko, D. S., Cohen, A. M. See Wortzman, Besbris, and Cohen. Corder, M. P. See Patii, Corder. Jochimsen, and

DECEMBER 1980 4843 Author Index to Volume 40

Dick, 4076 Ryan, Thomas, Lehr, Kumar, Koreeda. Akagi, Ellison, and Martin, 1311 Coriell, L. See Hashem, Bootsma, Keijzer. Utah, Dansette, Yagi, Jerina, and Conney, 642 Demetriades, M. See Meyn. Corry, Fletcher, and Greene, Coriell, Thomas, and Cleaver, 13 Darzynkiewicz, Z. See Petralia, Soprano, Po- Demetriades, 1136 Corry, P. M. See Barlogie, Corry, and Drewinko, chron, Darzynkiewicz, TrÃ¡ganos, and Baserga, Demi, E., and Oesterle, D. Histochemical Dem 1165; Meyn, Corry, Fletcher, and Demetriades, 3177; TrÃ¡ganos, Evenson, Staiano-Coico, Dar onstration of Enhanced Glutathione Content in 1136 zynkiewicz, and Melamed, 671; TrÃ¡ganos, Enzyme-altered Islands Induced by Carcino Cory, J. G., and Fleischer, A. E. Mode of Inhibition Staiano-Coico, Darzynkiewicz, and Melamed, gens in Rat Liver, 490, Communication of Tumor Cell Ribonucleotide Reductase by 2,3- 2390 Dempo, K. See Enomoto, Dempo, Mori, and Onoe, Dihydro-1 H-pyrazolo[2,3-A]imidazole (NSC- Das Gupta, T. K. See Chaudhuri, Walker, Beattie, 1769; Kaneko, Dempo, Kaku, Yokoyama, Sa- 51143), 3891 and Das Gupta, 861 toh, Mori, and OnoÃ©,1658 Costa, M., and Mollenhauer, H. H. Phagocytosis Daskal, Y., Soloway, M. S., DeFuria, M. D., and Denk, H., Abdelfattah-Gad, M., Eckerstorfer, R., of Nickel Subsulfide Particles during the Early Crooke, S. T. Morphological Effects of Mito- and Talcott, R. E. Microsomal Mixed-Function Stages of Neoplastic Transformation in Tissue mycin C Administered Intravesically to Normal Oxidase and Activities of Some Related En Culture, 2688 Mice and Mice with fV-[4-<5-Nitro-2-furyl)-2-thia- zymes in Hyperplastic Nodules Induced by Cox, R. DNA Methylase Inhibition in Vitro by N- zolyljformamide-induced Bladder Neoplasms, Long-Term Griseofulvin Administration in Mouse Methyl-N'-nitro-N-nitrosoguanidine, 61 261 Liver, 2568 Craig, R. W. See Walsh, Craig, and Agarwal, 3286 Daub, G. H. See Iyer, Lyga, Secrist, Daub, and Denning, G. M. See Yoo, ChiÃ¹, Spector, Whi Craighead, J. E. See Mossman, Ezerman, Adler, Slaga, 1073 leaker, Denning, and Lee, 1084 and Craighead, 4403 Dave, C. See Mikles-Robertson, Dave, and Porter, Deprez-DeCampeneere, D. See Jaenke, Deprez- Craven, P. A. See DeRubertis and Craven, 4589 1054 DeCampeneere, and Trouet, 3530 Creaven, P. J. See Pavelic, Slocum, Rustum, Dave, S. See Pavelic, Dave, Bialkowski, Priore, Derge, J. G. See Hampar, Boyd, Derge, Zweig. Creaven, Karakousis. and Takita, 2160; Pav and Greco. 4617 Eader. and Showalter, 2213 elic, Slocum. Rustum, Creaven, Nowak. Karak Davis, B. B. See Zenser, Mattammal, Armbrecht, DeRubertis, F. R., and Craven, P. A. Early Alter ousis, Takita, and Mittelman, 4151 and Davis, 2839; Zenser, Mattammal, and ations in Rat Colonie Mucosal Cyclic Nucleotide Croisy, A. See Zajdela. Croisy, Barbin, Malaveille. Davis, 114 Metabolism and Protein Kinase Activity Induced Tomatis, and-Bartsch. 352 Davis, D. W. See Ghanta. Hiramoto, Davis, and by 1,2 Dimethylhydrazine, 4589 Croisy-Delcey, M. See Levin, Wood, Chang, Utah, Hiramoto, 2372 De Sombre, E. R. See Everson, Lippman, Thomp Croisy-Delcey, Yagi, Jerina, and Conney, 3910; Davis, F. M. See Reiners, Davis, and Busch, 1367 son, McGuire, Wittliff, De Sombre, Jensen, Sin- Perin-Roussel, Croisy-Delcey, Mispelter, Sa- Davis, G. W. See Zwilling and Davis, 3455 ghakowinta, Brooks, and Neifeld, 991 guem. Chalvet, Ekert, Fouquet, Jacquignon, Davis, T. E. See Rose and Davis, 4043 Dethlefsen, L. A. See Olsen, Glasgow, and Deth- Lhoste, Muel, and Zajdela, 1742; Wood, Chang, Dawson. G. See Golomb, Nathans, and Dawson, lefsen, 853 Levin, Ryan, Thomas, Croisy-Delcey, Utah, Yagi, 1907 Detke, S., Stein, J. L., and Stein, G. S. Influence Jerina, and Conney, 2876 Dawson, J. R. See Hess, Gall, and Dawson, 1842, of Chlorambucil, a Bifunctional Alkylating Agent, Crooke, S. T. See Daskal, Soloway. DeFuria, and 4495 on DNA Replication and Histone Gene Expres Crooke, 261; DuVernay. Pachter, and Crooke, Day, J. L. See Maybaum, Ullman, Mandel, Day, sion in HeLa S3 Cells, 967 387; Mirabelli, Huang, and Crooke. 4173; and Sadee, 4209 Deutsch, E. See Ganzinger and Deutsch, 1300 Mong, Huang, Prestayko, and Crooke, 3313, Day, N. E. SeeTagnon, Blot, Stroube. Day, Morris, DeVita, V. T., Jr. See Speyer, Collins, Dedrick, 3318 Peace, and Fraumeni, 3875 Brennan, Buckpitt, Londer, DeVita, and Myers, Crutchley, D. J., Conanan, L. B., and Maynard, Day, N. K. See Gordon, Moroff, Hurvitz, Matus, 567 J. R. Induction of Plasminogen Activator and MacEwen, Good, and Day, 3627 Dewerie-Vanhouche, J. See Laurent, Dewerie- Prostaglandin Biosynthesis in HeLa Cells by 12- de Both, N. J., Kwak, E., and Klootwijk-van Vanhouche, Machin, and Hildebrand. 939 O-Tetradecanoylphorbol-13-acetate, 849 Dijke, E. Erythrocyte Production and Survival in DeWys, W. D., Allegra, J. C., Simon, R., and Csako, G., Binder, R. A., Kales, A. N., and Neefe, Rauscher Murine Leukemia Virus-Infected Lippman, M. E. A Proposed Model for the Pre J. R. Cloning of Human Lymphocytes Reactive BALB/C Mice, 4270 diction of Response to Endocrine Therapy in with Autologous Leukemia Cells, 3218 DeClerck. Y. A. See Jones and DeClerck, 3222 Breast Cancer from the Estrogen Receptor Sta Cummins, R. R., and Balinsky, D. Activities of DeClerck, Y. A., and Jones, P. A. Effect of A- tus of One Site and the Number of Metastatic Some Enzymes of Pyrimidine and DNA Synthe scorbic Acid on the Resistance of the Extracel Sites. 2423 sis in a Rat Transplantable Hepatoma and Hu lular Matrix to Hydrolysis by Tumor Cells, 3228 DeWys, W. D., and Bathina, S. H. Synergistic man Primary Hepatomas. in Cell Lines Derived DeCleve. A. See Boniver, DeclÃ¨ve, Finn, Honsik. Antileukemic Effect of Theophylline and 1,3- from These Tissues, and in Human Fetal Liver. Lieberman, and Kaplan, 544 Bis(2-chloroethyl)-1 -nitrosourea, 2202 1235 Dedrick, R. L. See Speyer, Collins, Dedrick, Bren- Diammond, E. J., Koprak, S., and Hollander, V. Cunningham, M. See Urano and Cunningham, 26 nan, Buckpitt, Lender, DeVita, and Myers, 567 P. Effect of High-Dose Progesterone on Growth Curtis, G. See Gold, Nesnow, Moore, Garland, Deen, D. F. See Weizsaecker and Deen, 3202 of Rat Mammary Carcinoma, 1091 Curtis, Howard, Graham, and Eisenstadt, 4482 DeFuria, M. D. See Daskal, Soloway. DeFuria, and Diamond, L. W., and Braylan, R. C. Flow Analysis of DNA Content and Cell Size in Non-Hodgkin's Cutler, R. G. See Fiorine. Ono, Cutler, and Getz, Crooke, 261 519 DeHoogh, D. K. See Estensen, DeHoogh, and Lymphoma, 703 Cysyk, R. L. See Karle, Anderson, Erlichman, and Cole, 1119 Diasio, R. B. See Armstrong and Diasio, 3333 Cysyk, 2938; Weinstein, Magin, Cysyk, and Za- Deichmann, W. B. See Radomski, Deichmann, Dick, F. R. See Patii, Corder. Jochimsen, and harko, 1388 Altman, and Radomski, 3537 Dick, 4076 DeLand, F. H. See Goldenberg, Kim, DeLand, Dicke, K. See Hersh, Patt, Murphy, Dicke, Zander, Bennett, and Primus, 2984*; Kim, DeLand, Nel Adegbite, and Goldman, 3134 son, Bennett, Simmons, Alpert, and Golden- Dickson, J. A. See Calderwood and Dickson, berg, 3008'; Pettit, DeLand, Bennett, and Gol- 4728 Dahl, G. A., Miller, E. C.. and Miller, J. A. Com denberg, 3043'; Primus, Bennett, Kim, De- Di Fiore, P. P. See Colletta, Di Fiore, Ferrentino, parative Carcinogenicities and Mutagenicities of Land, Zahn, and Goldenberg, 497; van Nagell, Pietropaolo, Turco, and Vecchio, 3369 Vinyl Carbamate, Ethyl Carbamate. and Ethyl N- Kim, Casper, Primus, Bennett, DeLand, and Digernes, V. See Saxholm and Digernes, 4254 Hydroxycarbamate, 1194 Goldenberg, 502 DiGiovanni, J., Berry, D. L., Gleason, G. L., Ki- Dahl, G. V. See Rivera, Evans, Dahl, Yee, and DeLand, F. H., Kim, E. E., and Goldenberg, D. shore, G. S., and Slaga, T. J. Time-dependent Pratt, 4250 M. Lymphoscintigraphy with Radionuclide-la- Inhibition by 2,3,7,8-Tetrachlorodibenzo-p- D'Alessio, G. See Vescia, Tramontano, Augusti- beled Antibodies to Carcinoembryonic Antigen, dioxin of Skin Tumorigenesis with Polycyclic Tocco, and D'Alessio, 3740 2997- Hydrocarbons, 1580 Danhauser, L. L., and Rustum, Y. M. Effect of DeLand, F. H., Kim, E. E., Simmons, G., and Dion, L. D. See Sasak, De Luca, Dion, and Silver Thymidine on the Toxicity, Antitumor Activity, Goldenberg, D. M. Imaging Approach in Ra- man-Jones, 1944 and Metabolism of 1-/3-o-Arabmofuranosylcy- dioimmunodetection, 3046' DiPaolo, J. A. See Doniger and DiPaolo, 582; tosine in Rats Bearing a Chemically Induced Delclos, K. B. See Dunphy, Delclos, and Blum- Mironescu, Epstein, and DiPaolo, 2411 Colon Carcinoma, 1274 berg, 3635 Dipple, A. See Bigger, Tomaszewski, Andrews, Danielson, K. G. See Zamora, Danielson, and DeLeo, A. B. See DuBois, Appella, Law, DeLeo, and Dipple, 655 Hosick, 4631 and Old, 4204 Distasio, J. A. See Durden and Distasio, 1125 Danielson, K. G., Anderson, L. W., and Hosick, Delihas, N. See Sutherland, Cimino, Delihas, Shih. DiStefano, J. F., Beck, G., Lysik, R., and Zucker, H. L. Selection and Characterization in Culture and Oliver, 1934 S. Pharmacological Studies Comparing the of Mammary Tumor Cells with Distinctive De Luca, L. M. See Sasak, De Luca, Dion, and Mechanism of Tumor-induced and Activated Growth Properties in Vivo, 1812 Silverman-Jones, 1944 Macrophage-induced Bone Marrow Cytolysis, Dansette, P. See Wood, Levin, Chang, Huang, deLuise, M. See Findlay. deLuise. Michelangeli. 1372

4844 CANCER RESEARCH VOL. 40 Author Index to Volume 40

Dittman, W. A., Kramer, R. J., and Bainton, D. F. 2529 Elkind, M. M. See Han. Hill, and Elkind. 3328 Electron Microscopic and Peroxidase Cyto- Durden, D. L., and Distasio, J. A. Comparison of Ell, P. J., and Khan, O. Radioisotope Section chemical Analysis of Pink Pseudo-Chediak-Hi- the Immunosuppressive Effects of Asparagi- Scanning, 3059' gashi Granules in Acute Myelogenous Leuke nases from Escherichia coli and Vibrio succin- Ellison, M. See Findlay. deLuise. Michelangeli, mia, 4473 ogenes. 1125 Ellison, and Martin, 1311 Diwan, B. A. See Boffa. Diwan. Gruss. and Allfrey, Duval, D. See Homo, Duval, Harousseau, Marie, Elting, J. J. See Shepherd. Vandre, Elting. and 1774; Szakal, Diwan, and Blackman, 2475 and Zittoun, 2601 Montgomery. 225 Dixon, R. L. See Emerole and Dixon, 2002 DuVernay. V. H., Pachter, J. A., and Crooke, S. Emerole, G. 0., and Dixon, R. L. Evaluation of Dobrossy, L., Pavelic, Z. P., Vaughan, M., Porter, T. Molecular Pharmacological Differences be Chemiluminescence Generation during Micro- N., and Bernacki, R. J. Elevation of Lysosomal tween Carminomycin and Its Analog, Carmino- somal Metabolism of Some Carcinogens, 2002 Enzymes in Primary Lewis Lung Tumor Corre mycin-11-methyl Ether, and Adriamycin, 387 Engel, L. W. See StrÃ¤uchen.Arya. Tralka, Engel, lated with the Initiation of Metastasis. 3281 Dworaczyk, D. See Porter, Dworaczyk, Ganis. and Young, 3880 Oocherty, J. J. See Oilman. Docherty, Clarke, and and Weiser, 2330 Enoch, P. G. See Hemstreet, Enoch, and Pretlow, Pawls. 4640 Dykes, P. W. See HiÃ±e,Bradwell, Reeder, Droic, 1043 Dodge, W. See Bryant, Smith, Sharma, and and Dykes, 2993' Enomoto, K., Dempo, K., Mori, M., and Onoe, T. Dodge, 4031 Dyott, T. See Rossi, Cantrell, Farber, Dyott, Car- Demonstration of Embryonic-type Hemoglobin Doellgast, G. J. See Taylor, Homesley. and Doell- rell, and Glusker, 2774 in Extramedullary Hematopoietic Cells in the gast, 4064 Liver during Experimental Liver Carcinogenesis Doll, J. See Poste, Doll. Hart, and Fidler. 1636 by 3'-Methyl-4-dimethylaminoazobenzene, Domeyer, B. E., and Sladek, N. E. Kinetics of 1769 Cyclophosphamide Biotransformation in Vivo, Ensign, N. A. See Kim, Kim, Hahn, and Ensign, 174 Eader, L. See Hampar, Boyd, Derge. Zweig, 3459 Donahue, P. R. See Essigmann, Donahue. Story. Eader, and Showalter, 2213 Ensminger, W. See Kirkwood, Ensminger, Ro- Wogan, and Brunengraber, 4085 Earnshaw, E. See Kumar, Kumar, Marsden, sowsky, Papathanasopoulos, and Frei, 107 Doniger, J., Barrett, S. F., and Robbins, J. H. Lynch, and Earnshaw, 2010 Eppenberger, U See Kung, Geyer, Eppenberger, Human Fibroblast Strain with Normal Survival Ebina, T. See Iseki. Ebina, and Ishida, 3786 and Huber, 4265 but Abnormal Postreplication Repair after Ultra Eckelman, W. C., Paik, C. H., and Reba, R. C. Epstein, P. M., Mills, J. S., Hersh, E. M., Strada, violet Light Irradiation, 2736 Radiolabeling of Antibodies. 3036' S. J., and Thompson, W. J. Activation of Cyclic Doniger, J., and DiPaolo, J. A. Excision and Post- Eckerstorfer, R. See Denk, Abdelfattah-Gad, Eck- Nucleotide Phosphodiesterase from Isolated replication DMA Repair Capacities, Enhanced erstorfer. and Talcott. 2568 Human Peripheral Blood Lymphocytes by Mito- Transformation, and Survival of Syrian Hamster Economou. S. See Anderson, Bonomi, Marogil. genie Agents. 379 Embryo Cells Irradiated by Ultraviolet Light. 582 Hendrickson. and Economou, 4127 Epstein, S. M. See Mironescu. Epstein, and Di Dormans, J. A. M. A. See Breed, Zimmerman, Edery, M. See Drosdowsky. Edery, Guggiari, Paolo. 2411 Dormans, and Pinedo, 2033 Montes-Rendon. Rudali, and Vives. 1674 Erickson, A. D. Assessment of Immune Re Dousa, T. P. See Scott and Dousa, 2860 Edgington, T. S. See Leung and Edgington, 316, sponses to Tumors Using Cryostat Sections of Dow, L. W., Bell, D. E., Poulakos, L., and Frid- 662 Bronchogenic Carcinoma, 3598 land, A. Differences in Metabolism and Cytotox- Edo, K. See Matsubara, Suzuki, Nakamura, Edo, Erickson, L. C. See Ramonas. Erickson, Rings icity between 9-/J-o-Arabinofuranosyladenine and Ishida, 2534 dorf, and Zaharko, 3704 and 9-/?-o-Arabinofuranosyl-2-fluoroadenine in Edstrom, S. See Lundholm, EdstrÃ¶m. Karlberg. Erickson, L. C., Ramonas, L. M., Zaharko, D. S., Human Leukemic Lymphoblasts, 1405 Ekman, and ScherstÃ©n, 2516; Lundholm, Ek- and Kohn, K. W. 4-Sulfidocyclophosphamides, Dowdle, E. B. See Wilson, Becker, Hoal, and man, Karlberg, EdstrÃ¶m,and ScherstÃ©n, 1680 Cytotoxicity, and DNA Crosslinking in Mouse Dowdle, 933; Wilson and Dowdle, 4817 Edwards, B. S. See Urban, Edwards, and Segal, Leukemia Cells in Vitro, 4216 Dragsten, P. See Raz, McLellan, Hart, Bucana, 1501 Erlichman, C. See Karle, Anderson, Erlichman, Hoyer, Sela, Dragsten, and Fidler, 1645 Edwards, C. C. See Jackson, Krance, Edwards, and Cysyk, 2938 Dray, S. See Hengst, Mokyr, and Dray, 2135; Whidden, and Gauthier, 667 Erlichman, C., Strong, J. M., and Chabner, B. A. Przepiorka, Mokyr, and Dray, 4565 Edwards, D. P., Murthy, S. R., and McGuire. W. Application of a Simple Competitive Protein- Drewinko, B. See Barlogie, Corry, and Drewinko. L. Effects of Estrogen and Antiestrogen on DNA binding Assay Technique to the Pharmacoki- 1165; Barlogie and Drewinko, 1973; Stragand. Polymerase in Human Breast Cancer, 1722 netics of /vXPhosphonacetylH-aspartate in Hu Bergerat, White, Hokanson. and Drewinko, Edwards, L. See Chiuten, Wiernik, Zaharko. and mans, 1902 2846 Edwards. 818 Erturk, E. See Rose, Pruitt, Stauber, ErtÃ¼rk,and Driedger, P. E., and Blumberg, P. M. Different Ege, G. N. Radiocolloid Lymphoscintigraphy in Bryan. 235 Biological Targets for Resiniferatoxin and Phor- Neoplastic Disease, 3065' Ervin, T. See Steele, Wang. Richie, Wilson. Ervin. bol 12-Myristate 13-Acetate, 1400; Structure- Egorin, M. J., Clawson, R. E., Cohen, J. L., Ross, Yankee, FallÃ³n, and Mannick, 2377 Activity Relationships in Chick Embryo Fibro- L. A., and Bachur, N. R. Cytofluorescence Lo Essex, M. See Grant, Essex, Gardner, and Hardy, blasts for Phorbol-related Diterpene Esters calization of Anthracycline Antibiotics, 4669 823 Showing Anomalous Activities in Vivo, 339 Egorin, M. J., Clawson, R. E., Ross, L. A., and Essigmann, J. M., Donahue, P. R., Story, D. L., Drohan. W., Cardiff, R. D., Lund, J. K., and Bachur, N. R. Cellular Pharmacology of N.N- Wogan, G. N., and Brunengraber. H. Use of Schlom, J. Correlation between the Detection Dimethyl Daunorubicin and N.W-Dimethyl Adria the Isolated Perfused Rat Liver to Study Carcin- of Specific Mouse Mammary Tumor Proviral Se mycin, 1928 ogen-DNA Adduci Formation from Aflatoxin B, quences and the Presence of Pulmonary MÃ©tas Ehrke, M. J. See Tomazic, Ehrke. and Mihich. and Sterigmatocystin, 4085 tases in Mice Bearing Spontaneous Mammary 2748 Estensen, R. D., DeHoogh. D. K., and Cole, C. F. Binding of [3H]12-O-Tetradecanoylphorbol-13- Tumors, 2316 Eidlen, D. M. See Evans. Madison, and Eidlen, Droic, Z. See HiÃ±e,Bradwell, Reeder, Droic, and 395 acetate to Intact Human Peripheral Blood Lym Dykes, 2993' Eigenbrodt, E. See Presek, Glossmann, Eigen- phocytes, 1119 Droller, M. J. See Owen, Gomolka, and Droller, brodt, Schoner, RÃ¼bsamen, Friis, and Bauer, Ettinger, D. S. See Order, Klein. Ettinger, Alder- son, Siegelman, and Leichner, 3001 â€¢; Waalkes, 3167 1733 Drosdowsky, M., Edery, M., Guggiari, M., Eisenstadt, E. See Gold and Eisenstadt, 3940; Abeloff, Woo, Ettinger. Ruddon, and Aldender- Montes-Rendon, A., Rudali, G., and Vives, C. Gold, Nesnow, Moore, Garland, Curtis, Howard, fer, 4420 Inhibition of Prolactin-induced Mammary Can Graham, and Eisenstadt, 4482 Evans, A. E. See Hann, Levy, and Evans, 1411 cer in C3Hf(XVII) Mice with the trans Isomer of Eisman. J. A. See Findlay, Michelangeli, Eisman, Evans, F. E. See Beland. Allaben. and Evans, Bromotriphenylethylene. 1674 Frampton. Moseley. Maclntyre, Whitehead, and 834; Morton, Beland. Evans, Fullerton, and DuBois, G. C., Appella, E., Law, L. W., DeLeo, A. Martin, 4764 Kadlubar. 751 B., and Old, L. J. Immunogenic Properties of Ekert, B. See Perin-Roussel, Croisy-Delcey, Mis- Evans, l. M., Hilf, R., Murphy, M., and Bosmann, Soluble Cytosol Fractions of Meth A Sarcoma pelter, Saguem, Chalvet, Ekert, Fouquet, Jac- H. B. Correlation of Serum. Tumor, and Liver Cells, 4204 quignon, Lhoste, Muel, and Zajdela. 1742 Serum Glycoprotein: rV-Acetylneuraminic Acid Dunigan, J. M. See Schwartz, Dunigan, Marsh, Ekman, L. See Lundholm, EdstrÃ¶m,Karlberg, Ek Transferase Activity with Growth of the and Handschumacher, 1885 man. and ScherstÃ©n.2516; Lundholm. Ekman, R3230AC Mammary Tumor in Rats and Rela Dunphy, W. G., Deletes, K. B., and Blumberg, Karlberg, EdstrÃ¶m,and ScherstÃ©n, 1680 tionship of the Serum Activity to Tumor Burden, P. M. Characterization of Specific Binding of Elder, D. E. See Herlyn, Clark, Mastrangelo, 3103 [3H]Phorbol 12.13-Dibutyrate and [3H]Phorbol Guerry, Elder, LaRossa, Hamilton, Bondi, Tuth- Evans, R., Madison, L. D., and Eidlen, D. M. 12-Myristate 13-Acetate to Mouse Brain. 3635 Â¡II,Steplewski, and Koprowski. 3602 Cyclophosphamide-induced Changes in the Dupont, C. See Laburthe, Rousset, Chevalier, Elias, E. G. See Auda, Vuthiganon, and Elias. Cellular Composition of a Methylcholanthrene- Boissard. Dupont, Zweibaum, and Rosselin, 2829 induced Tumor and Their Relation to Bone Mar-

Author Index to Volume 40 4845 Author Index to Volume 40

row and Blood Leukocyte Levels, 395 posomes to Improve Delivery of Macrophage- head, and Martin, 4764 Evans, R. M., Laskin, J. 0., and Hakala, M. T. Augmenting Agents to Alveolar Macrophages, Franchimont, P. See Santen, Collette, and Fran- Assessment of Growth-Limiting Events Caused 4460 chimont, 1181 by 5-Fluorouracil in Mouse Cells and in Human Findlay, D. M., deLuise, M., Michelangeli, V. P., Fraumeni, J. F., Jr. See Cantor and Fraumeni, Cells, 4113 Ellison, M., and Martin, T. J. Properties of a 2645; Tagnon, Blot, Stroube, Day, Morris, Evans, W. E. See Rivera, Evans, Dahl, Yee, and Calcitonin Receptor and Adenylate Cyclase in Peace, and Fraumeni, 3875 Pratt, 4250 BEN Cells, a Human Cancer Cell Line, 1311 Freedman, R. S. See Siciliano, Bordelon-Riser, Evenson, D. P. See TrÃ¡ganos. Evenson, Staiano- Findlay, D. M., Michelangeli, V. P., Eisman, J. A., Freedman, and Kohler, 283 Coico, Darzynkiewicz, and Melamed, 671 Frampton, R. J., Moseley, J. M., Maclntyre, I., Freeman, H. J., and San, R. H. C. Use of Un Evers, J. L. See Markus, Takita, Camiolo, Gora- Whitehead, R., and Martin, T. J. Calcitonin and scheduled DNA Synthesis in Freshly Isolated santi, Evers, and Hobika, 841 1,25-Dihydroxyvitamin D3 Receptors in Human Human Intestinal Mucosal Cells for Carcinogen Everson, R. B., Lippman, M. E., Thompson, E. Breast Cancer Cell Lines, 4764 Detection, 3155 B., McGuire, W. L., Wittliff, J. L., De Sombre, Fine, D. See Brattain, Strobel-Stevens, Fine, Freeman, H. J., Spiller, G. A., and Kim, Y. S. A E. R., Jensen, E. V., Singhakowinta, A., Webb, and Sarrif, 2142 Double-Blind Study on the Effects of Differing Brooks, S. C., Jr., and Neifeld, J. P. Clinical Finn, O. J. See Boniver, DeclÃ¨ve, Finn, Honsik, Purified Cellulose and Pectin Fiber Diets on 1,2- Correlations of Steroid Receptors and Male Lieberman, and Kaplan, 544 Dimethylhydrazine-induced Rat Colonie Neopla Breast Cancer, 991 Finne, J., Tao, T-W., and Burger, M. M. Carbo sia, 2661 Ewald, L. See Slaga, Gleason, Mills, Ewald, Fu, hydrate Changes in Glycoproteins of a Poorly Frei, E., Ill See Howell, Herbst, Boss, and Frei, Lee, and Harvey, 1981 Metastasizing Wheat Germ Agglutinin-resistant 1824; Kirkwood, Ensminger, Rosowsky, Papa- Ezerman, E. B. See Mossman, Ezerman, Adler, Melanoma Clone, 2580 thanasopoulos, and Frei, 107 and Craighead, 4403 Fioritoni, G., Bertolini, L., Torlontano, G., and Freireich, E. J See Ho, Carter, Brown, Hester, Revoltella, R. Cytochemical Characteristics of McCredie, Benjamin. Freireich, and Bodey, Leukopoietic Differentiation in Murine Etythro- 2441 leukemic (Friend) Cells. 866 Freyer, J. P., and Sutherland, R. M. Selective Fisher, B. Laboratory and Clinical Research in Dissociation and Characterization of Cells from Faanes, R. B. See Teller and Faanes, 2790 Breast Cancer-A Personal Adventure, 3863 Different Regions of Multiceli Tumor Spheroids, Fahmy, M. J., and Fahmy, O. G. Intervening DNA Fishman, W. H. See Chang, Angelus, and Fish- 3956 Insertions and the Alteration of Gene Expression man, 1506 Fridland, A. See Dow, Bell, Poulakos, and Frid- by Carcinogens, 3374 Fiske, W. W. See Liu, Fiske, and Chen, 4100 land, 1405 Fahmy, 0. G. See Fahmy and Fahmy, 3374 Fitzgerald, D. J., and Murray, A. W. Inhibition of Fried, J. See Murgo, Fried, Burchenal, Vale, Fairchild, E. See Blumer. Friedman, Meyer, Fair- Intercellular Communication by Tumor-promot Strife, Woodcock, Young, and Clarkson. 1543 child, Webster, and Speck, 4599 ing Phorbol Esters, 2935, Communication Friedlander, M. See Podhajcer, Friedlander, and Falahee, K. J. See Aust, Falahee. MÃ¤her,and Fladmoe, A. V. See Lam, Fladmoe, Hochalter, and Oraziani, 1344 McCormick, 4070 Wattenberg, 2824 Friedman, A. See Blumer, Friedman, Meyer, Fair- FallÃ³n, M. See Steele, Wang, Richie, Wilson, Er- Fleischer, A. E. See Cory and Fleischer, 3891 child, Webster, and Speck, 4599 vin, Yankee, FallÃ³n, and Mannick, 2377 Fletcher, S. E. See Meyn, Corry, Fletcher, and Friedman, J. See Loo, Friedman, Moore, Valdi Farber, A. J. See Rossi, Cantrell, Farber, Dyott, Demetriades, 1136 vieso, Marti, and Stewart, 86; Stewart. Leavens, Carrell, and Glusker, 2774 Fiorine, D. L., Ono, T., Cutler, R. G., and Getz, Friedman, Benjamin, Moore, Bodey, Valdivieso, Farber, E. See Lin, Kligman, and Farber. 3755; M. J. Regulation of Endogenous Murine Leu Burgess, Wiseman, and Loo. 3163 Ogawa, Solt. and Farber, 725; Solt, Cayama, kemia Virus-related Nuclear and Cytoplasmic Friend, C. See Gaziti and Friend, 1727 Sarma, and Farber, 1112; Tsuda, Lee, and Far RNA Complexity in C57BL/6J Mice of Increas Friis, R. R. See Presek, Glossmann, Eigenbrodt, ber. 1157 ing Age, 519 Schoner, RÃ¼bsamen,Friis, and Bauer, 1733 Parcel, Y. See Bart, Porzio, Kopf, Vilcek, Cheng, Flowers, H., and Click, M. C. Surface Labeling of Fry, D. W. See White, Carchman, Fry, and Gold and Parcel, 614 Sialic Acid Residues in BHK Cells and Viral man, 2400 Farrelly, J. G. A New Assay for the Microsomal Transformants, 1550 Fry, D. W., White, J. C., and Goldman, I. D. Metabolism of Nitrosamines, 3241 Fodstad, 0. See Tveit, Fodstad, Brogger, and Effects of 2,4-Dinitrophenol and Other Meta Faulkin. L. J. See Ashley, Cardiff. Mitchell. Olsnes, 949 bolic Inhibitors on the Bidirectional Carrier Faulkin. and Lund, 4232 Fodstad, 0., and Pihl, A. Synergistic Effect of Fluxes, Net Transport, and Intracellular Binding Fausto, N. See Atryzek, Tamaoki, and Fausto, Adriamycin and Ricin on L1210 Leukemic Cells of Methotrexate in Ehrlich Ascites Tumor Cells, 3713 in Mice. 3735 3669 Fazzini, E. P. See Raient, Cohen, Fazzini, Sarwal, Fogler, W. E. See Fidler, Raz, Fogler, Kirsh, Bug Fry, R. J. M. See Peraino, Staffeldt, Haugen, and Takahashi, 403 elski, and Poste, 4460 Lombard, Stevens, and Fry, 3268 Fefer, A. See Greenberg, Cheever, and Fefer, Fondy, T. P. See Babiarz-Tracy, McCarthy, Si Fu, J-j. L. See Tobler, Watts, and Fu, 1173 4428 mon, Burlingham, and Fondy, 3274 Fu, K. K. See Begg, Fu, Kane, and Phillips, 145 Feinberg, A., and Zedeck, M. S. Production of a Foote, L. J. See Kennel, Lankford, Foote, Tsak- Fu, P. C. See Shors, Fu, Matsumura, Cohen, and Highly Reactive Alkylating Agent from the Or- eres, Adams, and Ullrich, 2153 Benfield, 2288 ganospecific Carcinogen Methylazoxymethanol Forni, G. See Giovarelli, Radula, Ugazio, Forni, Fu, P. P. See Slaga. Gleason, Mills, Ewald, Fu, by Alcohol Dehydrogenase, 4446 and Cavallo, 3745 Lee, and Harvey, 1981 Feldman, M. See Khan. Feldman, and Hollander, Fortner, J. G. See Shiu and Fortner, 4081 Fujii, T. See Koizumi, Tamiya-Koizumi, Fujii, 1050 Fouquet, J. See Perin-Roussel, Croisy-Delcey, Okuda, and Kojima, 909 Fenselau, C. See Pallante, Fenselau, Mennel, Mispelter, Saguem, Chalvet, Ekert, Fouquet, Fujimoto, M. See Okada, Yamada, Kawashima, Brundrett, Appier, Rosenshein, and Colvin, Jacquignon, Lhoste, Muel, and Zajdela, 1742 Kitade, Okajima, and Fujimoto, 1663 2268 Fowler, A. K. See Strickland, Saviolakis, Weislow. Fujimura, S. See Tokita. Tanaka, Sekimoto, Ueno, Ferguson, D. J., and Urban, J. L. Tumorilysin Allen, Hellman, and Fowler, 3570 Okamoto, and Fujimura. 4287 Collected in Diffusion Chambers and Restraint Fox, J. J. See Balis, Borenfreund, Brown, and Fujita, K., Ito, S., Inoue, S., Yamamoto, Y., Tak- of Foreign Body Tumorigenesis, 1255 Fox, 493 euchi, J., Shamoto, M., and Nagatsu, T. Selec Ferguson, H. R. See Brunda, Mathews, Ferguson, Fox, R. M., Tripp, E. H., Piddington, S. K., and tive Toxicity of 5-S-Cysteinyldopa, a Melanin McClatchy, and Minden, 3211 Tattersall, M. H. N. Sensitivity of Leukemic Hu Precursor, to Tumor Cells in Vitro and in Vivo, Fernandez-Pol, J. A. Induction of Two Transfor man Null Lymphocytes to Deoxynucleosides, 2543 mation-sensitive Membrane Polypeptides in 3383 Fujita, T. See Matsukura, Kakita, Sueoka, Yosh- Normal Rat Kidney Cells by Iron Deprivation, Fox, R. M., Tripp, E. H., and Tattersall, M. H. N. imi, Hirata, Yokota, and Fujita, 3768 786 Mechanism of Deoxycytidine Rescue of Thymi- Fukuda, K., Shindo, H., Shimizu, F., Arakawa, Ferrentlno, M. See Colletta, Di Fiore, Ferrentino, dine Toxicity in Human T-Leukemic Lympho M., and Mizuhira, V. Ultrastructural Changes Pietropaolo, Turco, and Vecchio, 3369 cytes, 1718 Induced by 3-[(4-Amino-2-methyl-5-pyrimidi- Ferrane, S. See Imai and Ferrane, 2252 Fraile, R. J., Baker, L. H., Buroker, T. R., Horwitz, nyl)methyl]-1 -<2-chloroethyl)-1 -nitrosourea in Feyerabend, A. See Chan, Feyerabend, Busch, J., and Valtkevicius, V. K. Pharmacokinetics of L1210 Lymphocytic Leukemia Cells in Mice, and Busch, 3194 5-Fluorouracil Administered Orally, by Rapid In 133 Fidler, I. J. See Hart and Fidler, 2281 ; Kripke and travenous and by Slow Infusion, 2223 Fukui, M. See Yoshida, Kiyohara, Fukui, Atsumi, Fidler, 625; Poste, Doll, Hart, and Fidler, 1636; Fraley, E. E. See Bronson, Andrews, Solter, Cer- Ogino, Inaba, Tsukagoshi, and Sakurai, 3810 Raz, McLellan, Hart, Bucana, Hoyer, Sela, venka. Lange, and Fraley, 2500; Wang, Trend, Fukushima, M. See Yamanaka, Kalo, Nishida, Dragsten, and Fidler, 1645 Bronson, and Fraley, 796 Shimizu, Fukushima, and Ota, 2051 Fidler, I. J., Raz, A., Fogler, W. E., Kirsh, R., Frampton, R. J. See Findlay. Michelangeli, Eis Fukushima, S., and Cohen, S. M. Saccharin-in Bugelski, P., and Poste, G. The Design of Li man, Frampton, Moseley, Maclntyre, White- duced Hyperplasia of the Rat Urinary Bladder,

4846 CANCER RESEARCH VOL. 40 Author Index to Volume 40

734 Geiger, R. See Trown, Palleroni, Bohoslawec, Ri- rico, Glazer, Macdonald, and Schein, 1431 Fuller, B. B. See Meyskens and Fuller, 2194 chelo, Halpern, Gizzi, Geiger, Lewinski, Mach- Gleason, G. L. See DiGiovanni, Berry, Gleason, Fuller, D. J. M. See Gemer, Holmes, Stickney, lin, Jetten, and Jetten, 212 Kishore, and Slaga. 1580; Slaga, Gleason. Noterman, and Fuller, 432 George, R., and Goldfarb, S. Inhibition of 3-Hy- Mills. Ewald, Fu. Lee, and Harvey. 1981 Fullerton, N. F. See Morton, Beland, Evans, Ful- droxy-3-methylglutaryl Coenzyme A ReducÃase Gleiser, C. A. See Wang, Madanat. Kimball, lerton, and Kadlubar, 751 Activity in Morris Hepatoma 7800 after Intrave Gleiser, Ali, Kaufman, and van Eys. 1022 Fulton, D. S., Levin, V. A., Lubich, W. P., Wilson, nous Injection of Mevalonic Acid, 4717 Glenney, J. R. Jr., Kaulfus, P. J., Mclntyre, B. C. B., and Marion, L. J. Cerebrospinal Fluid Gerard, G. F. See Loewenstein, Lange, and Ger W., and Walborg, E. F., Jr. Identification and Polyamines in Patients with Glioblastoma Multi- ard, 4398 Partial Characterization of the Major Galacto- forme and Anaplastic Astrocytoma, 3293 Gerner, E. W., Holmes, D. K., Stickney, D. G., proteins Present at the Surface of AS-30D Hep- Furihata, C. See Saito, Sawamura. Umezawa, Noterman, J. A., and FÃ¼ller,D. J. M. Enhance atocellular Carcinoma Cells, 2853 Kanai, Furihata, Matsushima, and Sugimura, ment of Hyperthermia-induced Cytotoxicity by Click, A. D. See Kost, Hankins, Glick, and Krantz, 2539 Polyamines, 432 1150 Furth, E. E. See Skipper, Tannenbaum, Thilly, Gerweck, L. E., Jennings, M., and Richards, B. Click, M. C. See Flowers and Glick. 1550 Furth, and Bishop, 4704 Influence of pH on the Response of Cells to Glossmann, H. See Presek, Glossmann, Eigen- Single and Split Doses of Hyperthermia, 4019 brodt, Schoner, RÃ¼bsamen. Friis, and Bauer, Gessner, T. See Gurtoo, Vaught, Mannello, Pai- G 1733 gen, Gessner, and Bolanowska, 1305 Glusker, J. P. See Rossi, Cantrell, Farber. Dyott, Getz, M. J. See Fiorine. Ono, Cutler, and Getz, Carroll, and Glusker, 2774 Gabuzda, T. G. See Bloom, Ganjam, and Ga- 519 Godeneche, D., Madelmont, J-C., Moreau, MF., buzda, 2240 Gewirtz, D. A., Randolph, J. K., and Goldman, I. Montoloy, D., and Plagne, R. Disposition of the Gadek, K. M. See Wislocki, Gadek, Chou, Yang, D. Potent Bile Salt and Organic AniÃ³nInhibition Carcinostatic Agent 1-<2-Chloroethyl)-3-[r-{5'- and Lu, 3661 of Methotrexate Uptake and Accumulation in p - nitrobenzoyl -2',3'-isopropylidene)-a,/3-D-ri- Gahrton, G. See Wahren, Gahrton, and Hammar- the Freshly Isolated Rat Hepatocyte, 1852 bofuranosyl]-1-nitrosourea in Animals, 3351 strom, 2039 Gewirtz, D. A., White, J. C., Randolph, J. K., and Goerttler, K., Loehrke, H., Schweizer, J., and Gall, S. A. See Hess, Gall, and Dawson. 1842, Goldman, I. D. Transport, Binding, and Polyglu- Hesse, B. Two-Stage Tumorigenesis of Dermal 4495 tamation of Methotrexate in Freshly Isolated Rat Malanocytes in the Back Skin of the Syrian Gallagher, M. T. See Nasrallah, Gallagher, Priest, Hepatocytes, 573 Golden Hamster Using Systemic Initiation with and Trentin, 4159 Geyer, E. See KÃ¼ng,Geyer. Eppenberger, and 7,12-Dimethylbenz(a)anthracene and Topical Gamulin, S. See Romic-Stojkovic and Gamulin, Huber, 4265 Promotion with 12-O-Tetradecanoylphorbol-13- 4821 Chanta, V. K., Hiramoto, R. N., Davis, D. W., and acetate. 155 Ganapathi, R. See Krishan and Ganapathi, 3895 Hiramoto, N. S. Maintenance of MOPC 104E Gold, A., and Eisenstadt, E. Metabolic Activation Ganapathl, R., and Krishan, A. Effect of 2,3-Di- Myeloma in Plateau Phase, 2372 of Cyclopenta(cd)pyrene to 3,4-Epoxy Cyclc- hydro-1H-imidazo[1,2-b]pyrazole on the Prolif Chose, T., Norvell, S. T., Aquino, J., Belitsky, P., penta(cd)pyrene by Rat Liver Microsomes, eration of Mouse Leukemic and Normal Cells in Tai, J., Cuclu, A., and Blair, A. H. Localization 3940 of ' ''1-labeled Antibodies in Human Renal Cell Vivo, 1103 Gold, A., Nesnow, S., Moore, M., Garland, H., Ganapathi, R., Krishan, A., Wodinsky, I., Zubrod, Carcinomas and in a Mouse Hepatoma and Cor Curtis, G., Howard, B., Graham, D., and Eisen- C. G., and Lesko. L. J. Effect of Cholesterol relation with Tumor Detection by Photoscan- stadt, E. Mutagenesis and Morphological Content on Antitumor Activity and Toxicity of ning, 3018' Transformation of Mammalian Cells by a Non- Liposome-encapsulated 1-/5-o-Arabinofurano- Gibson, S. L., and Hilf, R. Regulation of Estrogen- Bay Region Polycyclic Cyclopenta(cd)pyrene sylcytosine in Vivo, 630 binding Capacity by Insulin in 7,12-Dimethyl- and Its 3,4-Oxide, 4482 Ganis, B. See Porter, Dworaczyk, Ganis, and benz (a)anthracene-induced Mammary Tumors Gold, P., and Shuster, J. Historical Development Weiser, 2330 in Rats, 2343 and Potential Uses of Tumor Antigens as Ganjam, V. K. See Bloom, Ganjam, and Gabuzda, Gilbert, H. S. See Mendelsohn, Gilbert, Christ- Markers of Human Cancer Growth, 2973* 2240 man, and Acs, 1469; Mendelsohn, Michl, Gil Goldberg, S. L. See Greengard, Head, and Gold Ganzinger, U., and Deutsch, E. Serum Sialyl- bert, Acs, and Christman, 3206 berg, 2295 transferase Levels as a Parameter in the Diag Gilbertson, S. See Broxmeyer, Ralph, Gilbertson, Golde, D. W. See Koeffler and Golde. 1858; Koef- nosis and Follow-up of Gastrointestinal Tumors, and Margolis, 3928 fler, Golde, and Lippman, 563 1300 Gilliland, D. G., and Collier, R. J. A Model System Goldenberg, D. M. An Introduction to the Radioim- Gardner, M. B. See Grant, Essex, Gardner, and Involving Anti-Concanavalin A for Antibody Tar munodetection of Cancer, 2957'. See a/so Hardy, 823 geting of Diphtheria Toxin Fragment A, 3564 DeLand. Kim. and Goldenberg, 2997'; DeLand. Garland, H. See Gold, Nesnow, Moore, Garland, Gilman, S. C., Docherty, J. J., Clarke, A., and Kim, Simmons, and Goldenberg, 3046'; Kim, Curtis, Howard, Graham, and Eisenstadt, 4482 Rawls, W. E. Reaction Patterns of Herpes Sim DeLand, Nelson, Bennett. Simmons, Alpert, and Garte, S. J. See Belman and Garte, 240 plex Virus Type 1 and Type 2 Proteins with Sera Goldenberg, 3008*; Pettit, DeLand, Bennett, Gasa, S., Makita, A., Kameya, T., Kodama, T., of Patients with Uterine Cervical Carcinoma and and Goldenberg, 3043"; Primus, Bennett, Kim, Araki, E., Yoneyama, T., Hirama, M., and Matched Controls, 4640 DeLand, Zahn, and Goldenberg, 497; Primus Hashimoto, M. Elevated Activities and Proper Gingell, R. See Langenbach, Gingell, Kuszynski, and Goldenberg, 2979*; van Nagell. Kim, Cas ties of Arylsulfatases A and B and B-Variant in Walker, Nagel, and Pour, 3463; Pour, Gingell, per, Primus, Bennett, DeLand, and Goldenberg. Human Lung Tumors, 3804 Langenbach, Nagel, Grandjean, Lawson, and 502 Gaudernack, G. See Olstad, Gaudernack, Ka Sal masi, 3585 Goldenberg, D. M., Kim, E. E., DeLand, F. H., plan, and Seljelid, 2054 Giovanella, B. C. See Lee, Giovanella, Stehlin. Bennett, S., and Primus, F. J. Radioimmuno- Gaulden, M. E. See Liang, Gaulden, and Herndon, and Howell, 1764 detection of Cancer with Radioactive Antibodies to Carcinoembryonic Antigen, 2984' 3426 Giovarelli, M., Padula, E., Ugazio, C., Forni, G., Gauthier, P. A. See Jackson, Krance, Edwards, and Cavallo, G. Strain- and Sex-linked Effects Goldenberg, G. J. See Begleiter, Grover, and Whidden, and Gauthier, 667 of Dietary Polyunsaturated Fatty Acids on Tu Goldenberg, 4489; Lam, Talgoy, and Golden- Gavosto, f. See Aglietta, Piacibello, and Gavosto, mor Growth and Immune Functions in Mice, berg, 3950 2507 3745 Goldfarb, S. See George and Goldfarb, 4717 Gazdar, A. F. See Baylin, Abeloff, Goodwin, Car Giuliani, F. C., and Kaplan, N. 0. New Doxorubi- Goldin, A. See Morimoto, Green, Rahman, Goldin, ney, and Gazdar, 1990; Carney, Gazdar, and cin Analogs Active against Doxorubicin-Re%ist- and Schein, 2762 Minna. 1820: Simms, Gazdar, Abrams. and ant Colon Tumor Xenografts in the Nude Mouse, Goldman, I. D. See Fry. White, and Goldman, Minna. 4356 4682 3669; Gewirtz. Randolph, and Goldman, 1852; Gazdar, A. F., Carney, D. N., Russell, E. K., Sims, Gizzi, N. See Trown, Palleroni, Bohoslawec. Ri- Gewirtz, White, Randolph, and Goldman, 573; H. L., Baylin, S. B., Bunn, P. A., Jr., Guccion. chelo, Halpern. Gizzi, Geiger, Lewinski, Mach- White, Carchman, Fry, and Goldman, 2400 J. G., and Minna, J. D. Establishment of Contin uous, Clonable Cultures of Small-Cell Carci lin, Jetten, and Jetten, 212 Goldman, R. See Hersh, Part, Murphy, Dicke, Glasgow, L. A. See Olsen, Glasgow, and Dethlet- noma of the Lung Which Have Amine Precursor Zander, Adegbite, and Goldman, 3134 Uptake and Decarboxylation Cell Properties, sen, 853 Goldsworthy, T. L. See Moore, Goldsworthy, and 3502 Glatt, H., Kaltenbach, E., and Oesch, F. Epoxide Pilot, 1449; Pitot, Goldsworthy, Campbell, and Gazitt, Y., and Friend, C. Polyamine Biosynthesis Hydrolase Activity in Native and in Mitogen-stim- Poland, 3616 Enzymes in the Induction and Inhibition of Dif ulated Lymphocytes of Various Human Donors, Colomb, H. M., Nathans, A. H., and Dawson, G. ferentiation in Friend Erythroleukemia Cells. 2552 Comparison between the Cellular Proteins of 1727 Glaubiger, D. L. See Bode, Magrath, Bleyer, Po- Hairy Cell Leukemia and the Leukemic Phase of Gee, T. S. See Arlin, Sklaroff, Gee, Kempin, How plack, and Glaubiger, 2184 Other Lymphoproliferative Diseases, 1907 ard. Clarkson, and Young, 3304 Glazer, R. I. See Ardalan, Cooney, Jayaram, Car- Gomi, K. See Kataoka. Oh-hashi, Sakurai, and

DECEMBER 1980 4847 Author Index to Volume 40

Gomi, 3832 Green, M. H., Brooks, T. L., Mendelsohn, J., and Menon, 3652 Gomolka. D. See Owen, Gomolka, and Droller, Howell, S. B. Antitumor Activity of L-Canavanine Haddox, M. K., Magun, B. E., and Russell, D. H. 3167 against L1210 Murine Leukemia, 535 Ornithine Decarboxylase Induction during G Good, R. A. See Gordon, Moroff, Hurvitz, Malus, Green, W. R. See Tarn, Green, and Nowinski, Progression of Normal and Rous Sarcoma Vi MacEwen, Good, and Day, 3627 3850 rus-transformed cells, 604 Goodenough, D. J. See Rockoff, Goodenough. Greenberg, G. See Greenberg, Caruana, Hoi- Hafstrom, L., Nobin, A., Persson, B., and andMclntire, 3054- comb, Greenberg, Parker, Louis, and White, Sundqvist, K. Effects of Catecholamines on Goodman, A. D., Hoekstra, S. J., and Marsh, P. 439 Cardiovascular Response and Blood Flow Dis S. Effects of Hypothyroidism on the Induction Greenberg, M. R., Caruana, J., Holcomb, B., tribution to Normal Tissue and Liver Tumors in and Growth of Mammary Cancer Induced by Greenberg, G., Parker, R., Louis, J., and Rats, 481 7,12-Dimethylbenz(a)anthracene in the Rat, White, P. High Cancer Mortality Rates from Haggard, M. E. See Carpentieri, Minguell, and 2336 Childhood Leukemia and Young Adult Hodg- Haggard. 2714 Goodrich-Smith. M. See Welsch, Brown, Good- kin's Disease and Lymphoma in the New Jersey- Haglund, U., Hayder, S., and Zech, L. Sister rich-Smith, Chiusane, and Moon, 3095 New York-Philadelphia Metropolitan Corridor, Chromatid Exchanges and Chromosome Aber Goodwin, G. See Baylin, Abeloff, Goodwin, Car 1950 to 1969, page 439 rations in Children after Treatment for Malignant ney, and Gazdar, 1990 Greenberg, P. D., Cheever, M. A., and Fefer, A. Lymphoma, 4786 Gordon, B. R., Moroff, S., Hurvitz, A. I., Matus, Detection of Early and Delayed Antitumor Ef Hague, B. F., Jr. See Reznik-Schuller, Lijinsky, R. E., MacEwen, E. G., Good, R. A., and Day, fects following Curative Adoptive Chemoimmu- and Hague, 2245 N. K. Circulating Immune Complexes in Sera of notherapy of Established Leukemia, 4428 Hahn, E. W. See Kim, Kim, Hahn, and Ensign, Dogs with Benign and Malignant Breast Dis Greene, A. See Hashem, Bootsma, Keijzer, 3459 ease, 3627 Greene, Coriell, Thomas, and Cleaver. 13 Hahn, G. M. Comparison of the Malignant Poten Gordon, C. See Warrell, Chou, Gordon, Tan, Rob Greengard, 0., Head, J. F., and Goldberg, S. L. tial of 10TA Cells and Transformants with Their erts, Sternberg, Philips, and Young, 4546 Uridine Kinase, Adenylate Kinase, and Guanase Survival Responses to Hyperthermia and to Am- Gordon, R. E., and Lane, B. P. Duration of Cell in Human Lung Tumors, 2295 photericin B, 3763. See a/so Li and Hahn, 4501 Cycle and Its Phases Measured in Synchronized Greenwell, P. See Kuhns, Oliver, Watkins, and Hakala, M. T. See Evans, Laskin, and Hakala, Cells of Squamous Cell Carcinoma of Rat Tra Greenwell, 268 4113 chea, 4467 Grier, A. H. See Parshad. Sanford, Jones, Tarone, HÃ¤kkinen, I. P. T., Heinonen, R., Inberg, M. V., Gore, H. See Lawrence, Shingleton, Gore, and Hoffman, and Grier, 4415 Jarvi, O. H., Vaajalahti, P., and Viikari, S. Clin- Soong, 1558 Griffin, M. J., and Noda, K-i. QuantitÃ¤tenof Epox- icopathological Study of Gastric Cancers and Gorman, M. S. See Clement, Gorman, Wodinsky, ide Hydrolase Released from Hyperplastic Nod Precancerous States Detected by Fetal Sulfo- Catane, and Johnson, 4165 ule and Hepatoma Microsomes, 2768 glycoprotein Antigen Screening. 4308 Goth-Goldstein, R. Inability of Chinese Hamster Grigor, M. R. See Singh, Grigor, and Thompson, Halberg, F. See Scheving, Burns, Pauly, and Hal- Ovary Cells to Excise O6-Alkylguanine, 2623, 1699 berg, 1511 Communication Grindey, G. B. See Kinahan, Pavelic, Leonard, Halpern, J. M. See Trown, Palleroni, Bohoslawec, Gotohda, E. See Yamada, Kawamura, Gotohda, Bloch, and Grindey, 598 Richelo, Halpern, Gizzi, Geiger, Lewinski, Akiyama. Hosokawa, Kodama. and Kobayashi. Grinspan, J. B. See Baird, Chemerys, Grinspan, Machlin, Jetten, and Jetten. 212 954 Mueller, and Levine, 1781 Mamada, H. See Nakata, Ochi, Kurisaki, Okano, Gottlieb, A. A., Chang, J., Buhrer, D. P., and Groopman, J. D., Busby, W. F., Jr., and Wogan, Hamada, Amitani, Tanabe, Ono, and Sakamoto, Brennessel, B. A. Isolation from Murine Mye G. N. Nuclear Distribution of Aflatoxin Ã¼and Its 127 loma and Leukemia Cells of a Selective Inhibitor Interaction with Histones in Rat Liver in Vivo, Hamamoto, S. T. See Pitelka, Hamamoto, and of DMA Polymerases, 758 4343 Taggart, 1588, 1600 Gould, M. N. Mammary Gland Cell-mediated Mu- Gross, J. F. See Chan, Chlebowski, Tong, Chen, Hamilton, B. See Osborne, Hamilton, Titus, and tagenesis of Mammalian Cells by Organ-specific Gross, and Bateman. 1263 Livingston, 2361 Carcinogens, 1836 Gross, L. The Search for Viruses as Etiological Hamilton, J. A. Stimulation of Macrophage Pros- Goulian, M. See Ingraham. Tseng, and Goulian, Agents in Leukemia and Malignant Lymphomas: taglandin and Neutral Protease Production by 998 The Role of the Happy Accident and the Pre Phorbol Esters as a Model for the Induction of Gout, P. W. See Noble, Beer, and Bout, 2437 pared Mind, 3405, Letter to the Editor Vascular Changes Associated with Tumor Pro Gout, P. W., Beer, C. T., and Noble, R. L. Prclac- Grotzinger, K. R. See Ozols, Willson, Grotzinger, motion, 2273 tin-stimulated Growth of Cell Cultures Estab and Young, 2743; Ozols, Willson, Weltz, Grot Hamilton, R. See Herlyn, Clark, Mastrangelo, lished from Malignant Nb Rat Lymphomas, 2433 zinger, Myers, and Young. 4109 Guerry, Elder, LaRossa, Hamilton, Bondi, Tut- Gowans, B. See Brox, Gowans, and Belch, 1169 Grover, J. See Begleiter, Grover. and Goldenberg, hill, Steplewski, and Koprowski, 3602 Grady, E. D. See Bale, Contreras, and Grady, 4489 HammarstrÃ¶m, S. See Wahren, Gahrton, and 2965' Grunberger, D. See Poirier, Santella, Weinstein, HammarstrÃ¶m, 2039 Graham, D. See Gold, Nesnow, Moore, Garland, Grunberger, Yuspa, 412 Hampar, B., Boyd, A. L., Derge, J. G., Zweig, M., Curtis, Howard, Graham, and Eisenstadt, 4482 Gruss, R. See Boffa, Diwan, Gruss, and Allfrey, Eader, L., and Showalter, S. D. Comparison of Gralla, E. J. See Swenberg, Kerns, Mitchell. 1774 Properties of Mouse Cells Transformed Spon Gralla, and Pavkov, 3398 Guccion, J. G. See Gazdar, Carney, Russell, taneously by Ultraviolet Light-irradiated Herpes Grandjean, C. See Pour, Gingell, Langenbach, Sims, Baylin, Bunn, Guccion, and Minna, 3502 Simplex Virus or by Simian Virus 40, page 2213 Nagel, Grandjean, Lawson, and Salmasi, 3585 Guclu, A. See Ghose, Norvell, Aquino, Belitsky, Han, A., Hill, C. K., and Elkind, M. M. Repair of Grant, C. K., Essex, M., Gardner, M. B., and Tai, Guclu, and Blair, 3018' Cell Killing and Neoplastic Transformation at Hardy, W. D., Jr. Natural Feline Leukemia Virus Guerry, D., IV See Herlyn, Clark, Mastrangelo, Reduced Dose Rates of '"Co -y-Rays, 3328 Infection and the Immune Response of Cats of Guerry, Elder, LaRossa, Hamilton, Bondi, Tut- Hanawalt, P. C. See Kaye, Smith, and Hanawalt, Different Ages, 823 hill, Steplewski, and Koprowski, 3602 696 Grant, S., and Cadman, E. Altered 5-Azacytidine Guggiari, M. See Drosdowsky, Edery, Guggiari, Handschumacher, R. E. See Schwartz, Dunigan, Metabolism following 3-Deazauridine Treatment Montes-Rendon, Unciali, and Vives, 1674 Marsh, and Handschumacher, 1885 of L5178Y and Human Myeloblasts, 4000 Gulino, A., and Pasqualini. J. R. Specific Binding Hankins, W. D. See Kost, Hankins, Glick, and Grant, S., Lehman, C., and Cadman, E. Enhance and Biological Response of Antiestrogens in the Krantz, 1150 ment of 1-/?-D-Arabinofuranosylcytosine Accu Fetal Uterus of the Guinea Pig, 3821 Hann, H-W. L., Levy, H. M., and Evans, A. E. mulation within L1210 Cells and Increased Cy- Cullino, P. M. See Arafah, Gullino, Manni, and Serum Ferritin as a Guide to Therapy in Neuro totoxicity following Thymidine Exposure. 1525 Pearson, 4628 blastoma, 1411 Grayhack, J. T. See Rowland, Henneberry, Gurka, D. P., See Scarpelli, Rao, Subbarao, Bev- Hannan, M. A. See Kunz, Hannan, and Haynes, Oyasu, and Grayhack, 4524 ersluis, Gurka, and Hollenberg, 67 2323 Oraziani. Y. See Podhajcer. Friedlander, and Gra- Gurtoo. H. L., Vaught, J. B., Mannello, A. J., Hansen, H. H. See Vindelev, Hansen, Christensen, ziani, 1344 Paigen, B., Gessner, T., and Bolanowska, W. Spang-Thomsen, Hirsch, Hansen, and Nissen, Greco, W. R. See Pavelic, Dave, Bialkowski, Pri High-Pressure Liquid Chromatographie Analy 4295 ore, and Greco. 4617 sis of Benzo(a)pyrene Metabolism by Human Hansen, M. See Vindelav, Hansen, Christensen, Green, C. L., Pretlow, T. P., Tucker, K. A., Brad Lymphocytes from Donors of Different Aryl Hy Spang-Thomsen, Hirsch, Hansen, and Nissen, ley, E. L., Jr., Cook, W. J., Pitts, A. M., and drocarbon Hydroxylase Inducibility and Antipyr- 4295 Pretlow, T. G., II Large-Capacity Separation of ine Half-Lives, 1305 HarÃ¡, A. See Koji, Ishii, Munehisa, Kusumoto, Malignant Cells and Lymphocytes from the Furth Nakamura, Tamenishi, HarÃ¡, Kobayashi, Tsu- Mast Cell Tumor in a Reorienting Zonal Rotor, kada, Nishi, and Hirai, 3013* 1791 HarÃ¡,Y., Steiner, M., and Baldini, M. G. Charac Green, D. See Morimoto, Green, Rahman, Goldin, terization of the Platelet-aggregating Activity of and Schein, 2762 Haberman, H. F. See Pawlowski, Haberman. and Tumor Cells, 1217; Platelets as a Source of

4848 CANCER RESEARCH VOL. 40 Author Index to Volume 40

Growth-promoting Factor(s) for Tumor Cells, Heinonen, R. See HÃ¤kkinen, Heinonen, Inberg, Hesse, B. See Goerttler, Loehrke, Schweizer, and 1212 JÃ¤rvi,Vaajalahti, and Viikari, 4308 Hesse, 155 Harada, N. See Kawajiri, Yonekawa, Harada, No- Heintz, N., Linie, B., Bresnick, E., and Schaeffer, Hester, J. See Ho, Carter, Brown, Hester, Mc- shiro, Omura, and Tagashira, 1652 W. I. Malignant Transformation of Cultured Rat Credie, Benjamin, Freireich, and Bodey, 2441 Haran-Ghera, N. See Spira, Babonits, Wiener, Hepatocytes by (+)- and ( - >-(rans-7,8-Dihydro- Higashi, H. See Ohtsuru, Ishii, Takai. Higashi, and Ohno, Wirschubski, Haran-Ghera, and Klein, 7,8-dihydroxybenzo(a)pyrene, 1281 Kosaki, 477 2609 Hellman, A. See Strickland, Saviolakis, Weislow. Higgins, J. See Lutz, Pedersen, Higgins, Harber, L. C. See Sutherland, Harber, and Ko- Allen, Hellman, and Fowler, 3570 HÃ¼bscher,Troy, and Theilen, 3642 chevar, 3181 Hellman, S. Improving the Therapeutic Index in Hildebrand, J. See Laurent, Dewerie-Vanhouche, Harcourt, S. A. See Arieti and Harcourt, 926 Breast Cancer Treatment. The Richard and Machin, and Hildebrand, 939 Hard, G. C., Clarke, F. M., and Toh, B. H. Com Hinda Rosenthal Foundation Award Lecture, Hilf, R. See Evans, Hilf, Murphy, and Bosmann, parison of Polypeptide Profiles in Normal and 4335 3103; Gibson and Hilf, 2343 Transformed Kidney Cell Lines Derived from Hemminki, K. See Stout, Hemminki, and Becker, Hill, C. K. See Han, Hill, and Elkind. 3328 Control, Dimethylnitrosamine-treated, and 3579 Hill, H. Z., and Setlow, R. B. Postreplication Re Renal Tumor-bearing Rats, with Particular Ref Hernstreet. G. P., Ill, Enoch, P. G., and Pretlow, pair in Three Murine Melanomas, a Mammary erence to Contractile Proteins, 3728 T. G., II Tissue Disaggregation of Human Renal Carcinoma, and a Normal Mouse Lung Fibro- Hardy, R. See Nadler, Stashenko, Hardy, Kaplan, Cell Carcinoma with Further Isopyknic and Iso- blastLine, 1867 Button, Kufe, Antman, and Schlossman, 3147 kinetic Gradient Purification, 1043 Hilliard, S. See Roberts, Hilliard, and Peck, 4225 Hardy, W. D., Jr. See Grant, Essex, Gardner, and Henderson, I. C. See Lampidis, Henderson, Israel, HiÃ±e,K. R., Bradwell, A. R., Reeder, T. A., Droic, Hardy, 823 and Can olios 3901 Z., and Dykes, P. W. Radioimmunodetection of Harousseau, J. L. See Homo, Duval, Harousseau, Henderson, W. R. See Newton, Henderson, and Gastrointestinal Neoplasms with Antibodies to Marie, and Zittoun, 2601 Sporn, 3413 Carcinoembryonic Antigen. 2993' Hart, I. R. See Poste, Doll, Hart, and Fidler, 1636; Hendrickson, C. See Anderson, Bonomi, Marogil, Hirai, H. See Koji, Ishii, Munehisa, Kusumoto, Raz. McLellan, Hart, Bucana, Hoyer, Sela, Hendrickson, and Economou, 4127 Nakamura, Tamenishi, HarÃ¡, Kobayashi, Tsu- Dragsten, and Fidler, 1645 Hengst, J. C. D., Mokyr, M. B., and Dray, S. kada, Nishi, and Hirai, 3013' Hart, I. R., and Fidler, I. J. Role of Organ Selec Importance of Timing in Cyclophosphamide Hirama, M. See Gasa, Makita, Kameya, Kodama, tivity in the Determination of Metastatic Patterns Therapy of MOPC-315 Tumor-bearing Mice, Araki, Yoneyama. Hirama, and Hashimoto, of B16 Melanoma, 2281 2135 3804 Harvey, R. G. See Slaga, Gleason, Mills, Ewald, Henkelman, M. S. See Teulings, van Gilse, Hen- Hiramoto, N. S. See Ghanta, Hiramoto, Davis, and Fu. Lee, and Harvey, 1981 kelman. Portengen, and Alexieva-Figusch, Hiramoto, 2372 Hashem, N., Bootsma, D., Keijzer, W., Greene, 2557 Hiramoto, R. N. See Ghanta, Hiramoto, Davis, and A., Coriell, L., Thomas, G., and Cleaver, J. E. Henneberry, M. O. See Rowland, Henneberry, Hiramoto, 2372 Clinical Characteristics, DNA Repair, and Com Oyasu, and Grayhack, 4524 Hirano. T., Ringsdorf, H., and Zaharko, D. S. plementation Groups in Xeroderma Pigmento- Henriksen, O. B. See Berresen, Henriksen, and Antitumor Activity of Monomeric and Polymeric sum Patients from Egypt. 13 Christensen. 4320 Cyclophosphamide Derivatives Compared with Hashimoto, M. See Gasa, Makita, Kameya, Ko- Heppner, G. H. See Miller, Miller, Leith, and in Vitro Hydrolysis. 2263 dama, Araki, Yoneyama, Hirama, and Hashi Heppner, 3977 Hirao, F. See Yoshimoto, Inoue, lizuka, Nishikawa. moto, 3804 Herbrink, P., Moen, J. E. T., Brouwer, J., and Sakatani, Ogura, Hirao, and Yamamura. 4301 Hatcher, J. F. See Pamukcu, Yalciner, Hatcher, Warnaar, S. O. Detection of Antibodies Cross- Hirata, Y. See Matsukura, Kakita, Sueoka, Yosh- and Bryan, 3468 Reactive with Type C RNA Tumor Viral p30 imi, Hirata, Yokota, and Fujita, 3768 Hattori, K. See Kitao and Hattori, 1351 Protein in Human Sera and ExÃºdate Fluids, 166 Hirsch, F. R. See Vindelov, Hansen, Christensen, Haugen, D. A. See Peraino, Staffeidt, Haugen, Herbst, A. L. See Check, Hunter, Rosenberg, and Spang-Thomsen, Hirsch, Hansen, and Nissen, Lombard, Stevens, and Fry, 3268 Herbst, 4612 4295 Hawkins, E. F., Horn, D., and Markland, F. S., Herbst, K. See Howell, Herbst, Boss, and Frei, Hitchins, V. M., Laine, B. M., and Hutton, J. J. Jr. Receptor for Glucocorticoids in RPMI 3460 1824 Genetic Regulation of Aryl Hydrocarbon Hy- Melanoma Cells, 2174 Herchuelz, A. See Malaisse, Sener, Herchuelz, droxylase in Primary Cultures of Fetal Cells Es Hawley-Nelson, P. See Yuspa, Hawley-Nelson, Carpinelli, Poloczek, Winand, and Castagna, tablished from Inbred Strains of Mice, 424 Koehler, and Stanley, 4694 3827 Ho, D. H. W., Carter, C. J., Brown, N. S., Hester, Hay, J. See Macnab, Visser, Jamieson, and Hay, Herlyn, D. M., Steplewski, Z , Herlyn, M. F., and J., McCredie, K., Benjamin, R. S., Freireich, E. 2074 Koprowski, H. Inhibition of Growth of Colorectal J, and Bodey, G. P. Effects of Tetrahydrouridine Hayakawa, T. See Shimizu, Ushio, Hayakawa, Carcinoma in Nude Mice by Monoclonal Anti on the Uptake and Metabolism of 1-ÃŸ-o-Arabi- and Mogami, 1341 body, 717 nofuranosylcytosine in Human Normal and Leu- Hayat, M. See Mori, Jasmin. Hayat, Macdonald, Herlyn, M. F. See Herlyn, Steplewski, Herlyn, and kemic Cells, 2441 and Math, 4282 Koprowski, 71 7 Ho, K. P. See Pewnim, Adams, and Ho, 1360 Hayata, I. See Kitamura, Uchida, Hayata, Yama- Herlyn, M. F., Clark, W. H., Jr., Mastrangelo, M. Hoal, E. G. See Wilson, Becker, Hoal, and Dowdle, guchi. Okamoto. Narita, and Matsumoto, 4781 J., Guerry. D., IV, Elder, 0. E., LaRossa, D., 933 Hayder, S. See Haglund, Hayder, and Zech, 4786 Hamilton, R., Bondi, E., Tuthill, R., Steplewski, Hobika, G. H. See Markus, Takita, Camiolo, Cor- Haynes, R. H. See Kunz, Hannan. and Haynes. Z., and Koprowski, H. Specific Immunoreactiv- asanti, Evers, and Hobika, 841 2323 ity of Hybridoma-secreted Monoclonal Anti-Mel Hochalter, J. B. See Lam, Fladmoe, Hochalter, Head, J. F. See Greengard, Head, and Goldberg, anoma Antibodies to Cultured Cells and Freshly and Wattenberg, 2824 2295 Derived Human Cells, 3602 Hodach, A. See Von Hoff, Casper, Bradley, Trent, Hecht, S. S. See LaVoie, Hecht, Amin, Bedenko, Herndon, J. H., Jr. See Liang, Gaulden, and Hern- Hodach, Reichert, Makuch, and Altman, 3591 and Hoffmann, 4528 don, 3426 Hoekstra, S. J. See Goodman. Hoekstra, and Hecht, S. S., Chen, C-h. B., Ohmori, T., and HerrÃ³n, D. C., and Shank, R. C. Methylated Pu- Marsh, 2336 Hoffmann, D. Comparative Carcinogenicity in rines in Human Liver DNA after Probable Di- Hoeschele, J. D. See Johnson, Hoeschele, Rahn, O'Neill, and Hsie. 1463 F344 Rats of the Tobacco-specific Nitrosa- methylnitrosamine Poisoning, 3116 mines, W-Nitrosonornicotine and 4-(W-Methyl- Hersh, E. M. See Epstein, Mills, Hersh, Strada, Hoffman, H. A. See Parshad, Sanford, Jones, N-nitrosaminoH -<3-pyridyl)-1 -butanone, 298 and Thompson. 379; Thompson, Ross, Strada, Tarone, Hoffman, and Grier. 4415 Hecht, S. S., Rivenson, A., and Hoffmann, D. Hersh, and Lavis, 1955 Hoffmann, D. See Hecht, Chen, Ohmori, and Hoff Tumor-initiating Activity of Dihydrodiols Formed Hersh, E. M., Pati, Y. Z., Murphy, S. G., Dicke, mann, 298; Hecht, Rivenson. and Hoffmann, Metabolically from 5-Methylchrysene, 1396 K., Zander, A., Adegbite, M., and Goldman, R. 1396; LaVoie, Hecht, Amin, Bedenko, and Hoff Hecht, S. S., Young, R., and Chen, C-h. B. Me Radiosensitive, Thymic Hormone-sensitive Pe mann, 4528 tabolism in the F-344 Rat of 4-(W-Methyl-W-Ni- ripheral Blood Suppressor Cell Activity in Can Hokanson, J. See Stragand, Bergerat. White, trosamino)-1-(3-Pyridyl)-1-Butanone, a To cer Patients, 3134 Hokanson, and Drewinko, 2846 bacco Specific Carcinogen. 4144 Herzfeld, A., and RÃ¢per,S. M. Relative Activities Holcomb. B. See Greenberg, Caruana, Holcomb, Heidelberger, C. See Boreiko, Mondai, Narayan, of Thymidylate Synthetase and Thymidine Ki- Greenberg, Parker, Louis, and White, 439 and Heidelberger, 4709; Landolph, Bhatt, Tel- nase in Rat Tissues, 744 Holland, J. F. See Chahinian, Beranek. Suzuki, fer, and Heidelberger, 4581; Mondai and Hei Hess, A. D., Gall, S. A., and Dawson, J. R. Inhi Bekesi, Wisniewski, Selikoff, and Holland, 181 delberger, 334; Woodman, Sarrif, and Heidel bition of Human Lymphoblastoid Cell Line Pro Hollander, V. P. See Diammond, Koprak, and berger, 507 liferation by Ascites Fluids from Ovarian Cancer Hollander, 1091; Khan, Feldman, and Hol Heidepriem, P. M. See Kulkarni, Heidepriem, and Patients, 4495; Partial Purification and Char lander, 1050; Platica, Bojko. and Hollander, Yielding, 2666 acterization of a Lymphocyte-inhibitory 579; Platica, Bojko, Steiner, and Hollander, Heilbrun, L. K. See Livingston, Titus, and Heil- Factor(s) in Ascitic Fluids from Ovarian Cancer 2229 brun. 2209 Patients, 1842 Hollenberg, P. F See Scarpelli, Rao, Subbarao,

DECEMBER 1980 4849 Author Index to Volume 40

Beversluis, Gurka. and Hollenberg. 67 Piver, Matsui, and Sandberg, 4512 4301 Holmes, D. K. See Gerner, Holmes, Stickney, Hsie, A. W. See Johnson, Hoeschele, Rahn, Ip, C. Ability of Dietary Fat to Overcome the Re O'Neill, and Hsie, 1463 Noterman, and Fuller, 432 sistance of Mature Female Rats to 7,12-Dimeth- Holtzer, H. See Pacifici and Holtzer, 2461; Pay- Huang, A. T. See Chang, Huang, and Joines, ylbenz(a)anthracene-induced Mammary Tumor- ette, Biehl, Toyama, Holtzer, and Holtzer, 2465 1002 igenesis, 2785 Holtzer, S. See Fayette, Biehl, Toyama, Holtzer, Huang, C. H. See Mirabelli, Huang, and Crooke, Ip, C., Yip, P., and Bernardis, L. L. Role of Pro- and Holtzer, 2465 4173; Mong, Huang, Prestayko, and Crooke, lactin in the Promotion of Dimethylbenz[a]an- Holtzman, S. See Shellabarger, McKnight. Stone, 3313, 3318 thracene-induced Mammary Tumors by Dietary and Holtzman, 1808; Stone, Holtzman, and Huang, M-T. See Wood, Chang, Huang, Levin, Fat, 374 Shellabarger, 3966 Lehr, Kumar, Thakker, Yagi, Jerina, and Con- Ip, M. M., Milholland, R. J., and Rosen, F. Func Homesley, H. D. See Taylor, Homesley, and Doell- ney, 1985; Wood, Levin, Chang, Huang, Ryan, tionality of Estrogen Receptor and Tamoxifen gast, 4064 Thomas, Lehr, Kumar, Koreeda, Akagi, Ittah, Treatment of R3327 Dunning Rat Prostate Ad Homo, F., Duval, D., Harousseau, J. L., Marie, J. Dansette, Yagi, Jerina, and Conney, 642 enocarcinoma, 2188 P., and Zittoun, R. Heterogeneity of the in Vitro Huber, P. R. See KÃ¼ng,Geyer, Eppenberger, and Iribe, H. See Yagawa, Kaku, Manabe, Yasumoto, Responses to Glucocorticoids in Acute Leuke Huber, 4265 Mashiba, Iribe, Yamagata, Takenaka, and No mia, 2601 Huber, S. A., Bigi, G., and Lucas, Z. J. Cycling of mura, 4791 Honma, Y. See Kasukabe, Honma. and Hozumi, Immune Resonses to a Syngeneic Murine Mam Irving, C. C. See Mochizuki, Irving, Anjo, Waka- 472; Sugiyama, Tomida, Honma, and Hozumi, mary Adenocarcinoma, 3484; Tumor-specific bayashi, Suzuki, and Okada, 162 3387 Suppressor Cells Induced by Immunization with Iseki, S., Ebina, T., and Ishida, N. Effects of Honsik, C. See Boniver, DeclÃ¨ve, Finn, Honsik, Spleen Cells from Tumor-bearing Animals, 3477 Caffeine on Neocarzinostatin-induced Inhibition Lieberman, and Kaplan, 544 Huberman, E. See Cabot, Welsh, Callaham, and of Cell Cycle Traverse in HeLa-S3 Cells, 3786 Hoogstraten, B. See Park, Amare, Savin, and Huberman, 3674; Jones and Huberman, 406 Ishida, N. See Iseki, Ebina, and Ishida, 3786; Hoogstraten, 1062 HÃ¼bscher, U. See Lutz, Pedersen, Higgins, Matsubara, Suzuki, and Ishida, 873; Matsubara, Hooker, W. M. See McMillan, Thaete, Hooker, HÃ¼bscher,Troy, and Theilen, 3642 Suzuki, Nakamura, Edo, and Ishida, 2534 and Roos, 1419 Huff, J. See Althouse, Huff, Tomatis, and Wil- Ishii, K., Yamazoe, Y., Kamataki, T., and Kato, Hoon, B. S. See Balk, Hoon, King, Loskutoff, bourn, 1 R. Metabolic Activation of Mutagenic Trypto- Mitchell, LeStourgeon, and Weselake, 1753 Hug, V. See Plunkett, Hug, Keating, and Chubb, phan Pyrolysis Products by Rat Liver Micro- Hopkins, H. A. See Looney, Ritenour, and Hop 588 somes, 2596 kins, 2179 Huggins, J. W., Trenbeath, T. P., Sherblom, A. Ishii, M. See Yoshima, Mizuochi. Ishii, and Kobata, Hoppenstand, R. D. See Theiss, Shimkin, Stoner, P., Howard, S. C., and Carraway, K. L. Glyco- 4276 Kniazeff, and Hoppenstand, 64 protein Differences in Solid and Ascites Forms Ishii, N. See Koji, Ishii, Munehisa, Kusumoto, Nak Horaguchi, K. See Tohda, Horaguchi, Takahashi, of the 13762 Rat Mammary Adenocarcinoma, amura, Tamenishi, HarÃ¡, Kobayashi, Tsukada, Oikawa, and Matsushima, 4775 1873 Nishi, and Hirai, 3013' Hori, T. See Matsuzawa, Mizuno, Yamamoto, Hori, Hunter, J. T. See Ashley, Zbar, Hunter, Rapp, and Ishii, Y. See Ohtsuru, Ishii. Takai, Higashi, and and Suzuki, 3361 Sugimoto, 4197 Kosaki, 477 Horn, D. See Hawkins, Horn, and Markland, 2174 Hunter, R. L. See Check, Hunter, Rosenberg, and Ishikawa, T., Takayama, S., and Ide, F. Autora- Horoszewicz, J. S. See Papsidero, Wojcieszyn, Herbst, 4612 diographic Demonstration of DNA Repair Syn Horoszewicz, Leong, Murphy, and Chu, 3032* Hurvitz, A. I. See Gordon, Moroff, Hurvitz, Matus, thesis in Rat TrachÃ©alEpithelium Treated with Horwitz, J. See Fraile, Baker, Buroker. Horwitz, MacEwen, Good, and Day, 3627 Chemical Carcinogens in Vitro, 2898 and Vaitkevicius, 2223 Husby, G. See Kaszubowski, Husby, Tung, and Ishikawa, T., Takayama, S., and Kitagawa, T. Hoshino, H. See Tanoooka, Hoshino, Tanaka, and Williams, 4648 Correlation between Time of Partial Hepatec- Nagase, 2547 Huseby, R. A. Demonstration of a Direct Carcino tomy after a Single Treatment with Diethylni- Hosick, H. L. See Danielson, Anderson, and Hos- genic Effect of Estradici on Leydig Cells of the trosamine and Induction of ATPase-deficient Is ick, 1812; Zamora, Danielson, and Hosick, Mouse, 1006 lands in Rat Liver, 4261 4631 Hutchison, D. J. Obituary: Kanematsu Sugiura, Isohashi, F., Tsukanaka, K., Terada, M., Nak- Hosokawa, M. See Minami. Kasai, Mizushima, 2625 anishi, Y., Tani, S., and Sakamoto, Y. Amino- Takeichi, Hosokawa, and Kobayashi, 2129; Ya- Hutson, J. C. See Stocco and Hutson, 1486 transferase Activities and Involution of the Thy mada, Kawamura, Gotohda, Akiyama, Hoso Hutton, J. J. See Hitchins, Laine, and Hutton, 424 mus in Rats Bearing AH 130 Tumors, 877 kawa, Kodama, and Kobayashi, 954 Hwang, C. G. See Sirica, Hwang, Sattler, and Israel, M. See Lampidis, Henderson, Israel, and Howard, B. See Gold, Nesnow, Moore, Gardland, Pilot, 3259 Canellos, 3901 Curtis, Howard, Graham, and Eisenstadt, 4482 Ito, S. See Fujita, Ito, Inoue, Yamamoto. Takeuchi, Howard, E. F., Cheng, C. Y., and Howard, J. S. I Shamoto, and Nagatsu, 2543 Mitogenic Activity and Plasminogen Activator in Ito, Y., Kishishita, M., and Yanase, S. Induction Harvest Fluid Concentrates from Mammary lacobelli, S. See Ranchetti, lacobelli, Carmignani, of Epstein-Barr Virus Antigens in Human Lym- Cells in Culture, 4385 Sica, Natoli, and Tonali, 2020 phoblastoid P3HR-1 Cells with Culture Fluid of Howard, J. See Arlin, Sklaroff, Gee, Kempin, Ide, F. See Ishikawa, Takayama, and Ide, 2898 Flusobacterium nucleatum, 4329, Communica Howard, Clarkson, and Young, 3304 Igarashi, K. See Ootsu, Kozai, Takeuchi, Ikeyama, tion Howard, J. S. See Howard, Cheng, and Howard, Igarashi, Tsukamoto. Sugino. Tashiro, Tsuka- Ittah, Y. See Levin, Wood. Chang. Ittah, Croisy- 4385 goshi, and Sakurai, 1707 Delcey, Yagi, Jerina, and Conney, 3910; Wood, Howard, S. C. See Huggins, Trenbeath, Sher- lida, H. See Tsuruo, Naganuma, lida, and Tsuka- Chang, Levin, Ryan, Thomas, Croisy-Delcey, blom, Howard, and Carraway, 1873 goshi, 4758 Ittah, Yagi, Jerina, and Conney, 2876; Wood, Howard, S. M. H., Theologides, A., and Shep- lizuka, H. See Yoshimoto, Inoue, lizuka, Nishi- Levin, Chang, Huang, Ryan, Thomas, Lehr, Ku pard, J. R. Comparative Effects of Vindesine, kawa, Sakatani, Ogura, Hirao, and Yamamura, mar, Koreeda, Akagi, Ittah, Dansette, Yagi, Jer Vinblastine. and Vincristine on Mitotic Arrest 4301 ina, and Conney, 642 and Hormonal Response of L1210 Leukemia Ikeyama, S. See Ootsu, Kozai, Takeuchi, Ikey Itze, L. See Vesselinovitch, Itze, Mihailovich, and Cells, 2695 ama, Igarashi, Tsukamoto, Sugino, Tashiro, Rao, 1538 Howell, A. See Wilson. Woods, Walker, and How- Tsukagoshi, and Sakurai. 1707 Ivanovic, V., and Weinstein, I. B. Genetic Factors ell, 486 Imai, K., and Ferrane, S. Indirect Rosette Mi- in Eschehchia coli That Affect Cell Killing and Howell, S. B. See Green, Brooks, Mendelsohn, croassay to Characterize Human Melanoma-as Mutagenesis Induced by Benzo(a)pyrene-7,8- and Howell, 535; Lee, Giovanella, Stehlin, and sociated Antigens Recognized by Operationally dihydrodiol 9,10-Oxide, 3508 Howell, 1764 Specific Xenoantisera, 2252 Iyer, A. P. See Knauer, Iyer, Banerjee, and Smith, Howell, S. B., Herbst, K., Boss, G. R., and Frei, Inaba, M. See Yoshida, Kiyohara, Fukui. Atsumi. 4368 E., Ill Thymidine Requirements for the Rescue Ogino, Inaba, Tsukagoshi, and Sakurai, 3810 Iyer, R. P., Lyga, J. W., Secrist, J. A., Ill, Daub, of Patients Treated with High-Dose Methotrex- Inberg, M. V. See HÃ¤kkinen, Heinonen, Inberg, G. H., and Slaga, T. J. Comparative Tumor- ate, 1824 JÃ¤rvi,Vaajalahti, and Viikari, 4308 initiating Activity of Methylated Benzo(a)pyrene Hoyer, L. C. See Raz, McLellan, Hart, Bucana, Ingraham, H. A., Tseng, B. Y., and Goulian, M. Derivatives in Mouse Skin, 1073 Hoyer, Sela, Dragsten. and Fidler, 1645 Mechanism for Exclusion of 5-Fluorouracil from lype, P. T. See McMahon and lype, 1249 Hozumi, M. See Kasukabe, Honma, and Hozumi, DMA, 998 lype, P. T., and Pontzer, C. H. Identification of 472; Sugiyama, Tomida, Honma, and Hozumi, Inoue, S. See Fujita, Ito, Inoue, Yamamoto, Tak Transformed Liver Cell Colonies Using Concan- 3387; Takenaga, Hozumi. and Sakagami, 914; euchi, Stiamolo, and Nagatsu, 2543 avalin A Attached to Agarose Beads, 4663 Tomida, Yamamoto. and Hozumi, 2919; Yama Inoue, S. See Oh-Uti, Inoue, and Minato, 1686 Izuml, T., Nagai, S., and Suginoshita, T. Serum moto, Tomida, and Hozumi, 4804 Inoue, T. See Yoshimoto, Inoue, lizuka, Nishi- Immunosuppression Test as a New Tool for Hreshchyshyn, M. M. See Wake, Hreshchyshyn, kawa, Sakatani, Ogura, Hirao, and Yamamura, Immunodiagnosis of Lung Cancer, 444

4850 CANCER RESEARCH VOL. 40 Author Index to Volume 40

1002 lodinated Thymidine Analogs, 5-lodo-2'-deox- Jones, C. A., and Huberman, E. A Sensitive yuridine and 5-lodo-5'-amino-2'.5'-dideoxyuri- Jackson, C. W., Krance, R. A., Edwards, C. C., Hepatocyte-mediated Assay for the Metabolism dine, 3491 Whidden. M. A., and Gauthier, P. A. Shortened of Nitrosamines to Mutagens for Mammalian Kann, H. E., Jr., Blumenstein, B. A., Petkas, A., Platelet Survival as a Cause of Thrombocyto- Cells, 406 and Schott, M. A. Radiation Synergism by Re penia in Mice with L1210 Leukemia, 667 Jones, G. M. See Parshad, Sanford, Jones, Tar- pair-inhibiting Nitrosoureas in L1210 Cells, 771 Jackson, D. V., Jr., Castle, M. C., Poplack, D. G., one, Hoffman, and Grier, 4415 Kann, H. E., Jr., Schott, M. A., and Petkas, A. and Bender, R. A. Pharmacokinetics of Vincris- Jones, P. A. See Benedict, Wheatley, and Jones. Effects of Structure and Chemical Activity on tine in the Cerebrospmal Fluid of Subhuman 2796; DeClerck and Jones, 3228 the Ability of Nitrosoureas to Inhibit DNA Repair, Primates, 722 Jones, P. A., and DeClerck, Y. A. Destruction of 50 Jackson, R. C., Lui, M. S., Boritzki, T. J., Morris, Extracellular Matrices Containing Glycopro- Kannan, R., Lyon, I., and Baker, N. Dietary Con H. P., and Weber, G. Purine and Pyrimidine teins. Elastin, and Collagen by Metastatic Hu trol of Lipogenesis in Vivo in Host Tissues and Nucleotide Patterns of Normal, Differentiating, man Tumor Cells. 3222 Tumors of Mice Bearing Ehrlich Ascites Carci and Regenerating Liver and of Hepatomas in Juarez-Salinas, H. See Jacobson. Levi, Juarez- noma, 4606 Rats. 1286 Salinas, Barton, and Jacobson, 1797 Kannan, R., Ookhtens, M., and Baker, N. Com- Jacobson, E. L. See Jacobson, Levi, Juarez-Sal Juranka, P., and Chan, V-L. Relative Cytotoxicity partmental Analysis of Linoleate and Palmitate inas, Barton, and Jacobson, 1797 of 9-j8-D-Arabinofuranosyladenine and 9-/ÃŒ-D- Turnover in a Murine Carcinoma, 2447 Jacobson, M. K. See Rankin, Jacobson, Mitchell, Arabinofuranosyladenine 5'-Monophosphate, Kaplan, G. See Olstad, Gaudernack, Kaplan, and and Busbee, 1803 4123 Seljelid. 2054 Jacobson, M. K., Levi, V., Juarez-Salinas, H., Kaplan, H. S. See Boniver, DeclÃ¨ve,Finn. Honsik. Barton, R. A., and Jacobson, E. L. Effect of Lieberman, and Kaplan, 544 Carcinogenic N-Alkyl-N-nitroso Compounds on Kaplan, N. O. See Giuliani and Kaplan, 4682 Nicotinamide Adenine Dinucleotide Metabolism, Kaplan, W. D. See Nadler, Stashenko, Hardy, 1797 Kadlubar, F. F. See Morton. Beland, Evans, Ful- Kaplan, Button, Kufe, Animan, and Schlossman, Jacquignon, P. See Perin-Roussel, Croisy-Del- lerton, and Kadlubar, 751 3147 cey, Mispelter, Saguem, Chalvet, Ekert, Fou- Kahan, B. D. See Rutzky, Kaye, Siciliano, Chao, Karakousis, C. See Pavelic, Slocum, Rustum, quet, Jacquignon, Lhoste, Muel, and Zajdela, and Kahan, 1443 Creaven, Karakousis, and Takita, 2160; Pav 1742 Kaighn, M. E. See Ohnuki, Mameli, Babcock. elic, Slocum, Rustum, Creaven, Nowak, Karak Jaenke, R. S., Deprez-DeCampeneere, D., and Lechner, and Kaighn, 524 ousis, Takita, and Mittelman, 4151 Trouet, A. Cardiotoxicity and Comparative Kakita, T. See Matsukura. Kakita, Sueoka, Yosh- Karasaki, S., Suh, M. H., Salas, M., and Ray Pharmacokinetics of Six Anthracyclines in the imi. Hirata, Yokota. and Fujita, 3768 mond, J. Cell Surface Adenosine 5'-Triphos- Rabbit, 3530 Kakizoe, T., Komatsu, H., Niijima, T., Kawachi, phatase as an in Vitro Marker of the Lineage Jamieson, A. T. See Macnab, Visser, Jamieson, T., and Sugimura, T. Increased Agglutinability and Cytodifferentiation of Oncogenic Epithelial and Hay, 2074 of Bladder Cells by Concanavalin A after Admin Cells from Rat Liver Parenchyma, 1318 Janik, P., Assaf, A., and Bertram, J. S. Inhibition istration of Carcinogens, 2006 Karlberg, I. See Lundholm, EdstrÃ¶m.Karlberg, of Growth of Primary and Metastatic Lewis Lung Kaku, M. See Yagawa, Kaku, Manabe. Yasumoto. Ekman. and Schersten. 2516; Lundholm, Ek- Carcinoma Cells by the Phosphodiesterase In Mashiba, Iribe, Yamagata. Takenaka, and No man, Karlberg, EdstrÃ¶m,and Schersten, 1680 hibitor Isobutylmethylxanthine, 1950 mura, 4791 Karle, J. M., Anderson, L. W., Erlichman, C., and Jarman, M. See Bryant, Jarman. Baker, Smith, Kaku, T. See Kaneko, Dempo, Kaku. Yokoyama, Cysyk, R. L. Serum Uridine Levels in Patients and Smyth, 4734 Satoh, Mori, and OnoÃ©,1658 Receiving N-(Phosphonacetyl)-L-aspartate. Jarvi, O. H. See HÃ¤kkinen. Heinonen, Inberg. Kakunaga, T. See Barrett, Sheela, Ohki. and Kak- 2938, Communication JÃ¤rvi,Vaajalahti. and Viikari, 4308 unaga, 1438 Kasai, M. See Minami, Kasai, Mizushima, Takei- Jasmin, C. See Mori, Jasmin, Hayat, Macdonald, Kalberer, J. T., Jr., and Morrison, B. H., Ill Na chi, Hosokawa, and Kobayashi, 2129 and Math, 4282 tional Cancer Institute Support for Scientific Kasukabe, T., Honma, Y., and Hozumi, M. En Jayaram, H. N. See Ardalan, Cooney, Jayaram. Conferences, 2617 hancement of Growth of a Mouse Macrophage Carneo. Glazer, Macdonald, and Schein, 1431 Kales, A. N. See Csako. Binder. Kales, and Neefe, Cell Line by a Tumor Promoter and Granulocyte- Jennings, M. See Gerweck. Jennings, and Rich 3218 Macrophage Colony-stimulating Factor. 472 ards, 4019 Kaltenbach, E. See Glatt, Kaltenbach. and Oesch, Kaszubowski, P. A., Husby, G., Tung, K. S. K., Jensen, E. V. See Everson, Lippman, Thompson, 2552 and Williams, R. C., Jr. T Lymphocyte Subpop- McGuire, Wittliff. De Sombre, Jensen, Singhak- Kalter, H., Mandybur, T. I., Ormsby, I., and War- ulations in Peripheral Blood and Tissues of Can owinta. Brooks, and Neifeld, 991 kany, J. Dose-related Reduction by Prenatal X- cer Patients, 4648 Jerina, D. M. See Buening, Levin, Wood, Chang, Irradiation of the Transplacental Neurocarcino- Kataoka, T., Ogihara, K., and Sakurai, Y. Immu- Lehr. Taylor, Yagi, Jerina, and Conney, 203; genicity of Ethylnitrosourea in Rats, 3973 noprophylactic and Immunotherapeutic Re Levin, Wood. Chang, Ittah, Croisy-Delcey, Yagi, Kamataki, T. See Ishii, Yamazoe, Kamataki, and sponse by Concanavalin A-bound Tumor Vac Jerina, and Conney, 3910; Wood, Chang, Kato, 2596; Sugiura, Yamazoe, Kamataki, and cine Enhanced by Chemotherapeutic Agents Huang, Levin, Lehr, Kumar, Thakker, Yagi, Jer Kato. 2910 Eliminating Possible Suppressors, 3839 ina, and Conney, 1985; Wood, Chang, Levin, Kamatani, N., and Carson, D. A. Abnormal Reg Kataoka, T., Oh-hashi, F., Sakurai, Y., and Gomi, Ryan, Thomas, Croisy-Delcey, Ittah, Yagi, Jer ulation of Methylthioadenosine and Polyamine K. In Vivo Potentiation of Concanavalin A-bound ina, and Conney, 2876; Wood, Levin, Chang, Metabolism in Methylthioadenosine Phospho- L1210 Vaccine by Antimacrophage Agents, Huang. Ryan, Thomas, Lehr, Kumar, Koreeda, rylase Deficient Human Leukemic Cell Lines, 3832 Akagi, Ittah. Dansette, Yagi. Jerina, and Con 4178 Kato, R. See Ishii, Yamazoe, Kamataki, and Kato. ney, 642 Kameya, T. See Gasa, Makita, Kameya, Kodama, 2596: Sugiura. Yamazoe, Kamataki, and Kato, Jetten, A. See Trown, Palleroni, Bohoslawec, Ri- Araki, Yoneyama, Hirama, and Hashimoto, 2910 chelo, Halpern, Gizzi, Geiger, Lewinski, Mach- 3804 Kato, T. See Yamanaka, Kato. Nishida. Shimizu, liti. Jetten, and Jetten, 212 Kanal, Y. See Saito, Sawamura, Umezawa, Kanai, Fukushima, and Ota, 2051 Jetten, M. E. R. See Trown, Palleroni, Bohos Furihata, Matsushima, and Sugimura, 2539 Katzenellenbogen, B. S. See Rorke and Katze- lawec, Richelo, Halpern, Gizzi, Geiger, Lewin Kane, L. J. See Begg, Fu. Kane, and Phillips, 145 nellenbogen. 3158 ski, Machlin, Jenen, and Jetten, 212 Kaneko, A., Dempo, K., Kaku, T., Yokoyama, S., Kaufman, M. W. See Wang. Madanat. Kimball. Jochimsen, P. R. See Patii, Corder, Jochimsen, Satoh, M., Mori, M., and OnoÃ©,T. Effect of Gleiser, Ali, Kaufman, and van Eys, 1022 and Dick, 4076 PhÃ©nobarbital Administration on Hepatocytes Kaulfus, P. J. See Glenney, Kaulfus. Mclntyre. Johnson, E. F., Levitt, D. S., Muller-Eberhard, Constituting the Hyperplastic Nodules Induced and Walborg, 2853 U., and Thorgeirsson, S. S. Catalysis of Diver in Rat Liver by 3'-Methyl-4-dimethylaminoazo- Kawachi, T. See Kakizoe, Komatsu, Niijima, Ka gent Pathways of 2-Acetylaminofluorene Metab benzene, 1658 wachi, and Sugimura, 2006 olism by Multiple Forms of Cytochrome P-450. Kaneko, M., and Cerniti. P. A. Excision of N- Kawajiri, K., Yonekawa, H., Harada, N., Noshiro, page 4456 Acetoxy-2-Acetylaminofluorene-induced DNA M., Omura, T., and Tagashira, Y. Immuno- Johnson, N. P., Hoeschele, J. D., Rahn, R. 0., Adducts from Chromatin Fractions of Human chemical Study on the Role of Different Types O'Neill, J. P., and Hsie, A. W. Mutagenicity. Fibroblasts, 4313 of Microsomal Cytochrome P-450 in Mutagen- Cytotoxicity, and DNA Binding of Plati- Kang, M-S., Song, C. W., and Levitt, S. H. Role esis by Chemical Carcinogens, 1652 num(ll)chloroammines in Chinese Hamster of Vascular Function in Response of Tumors in Kawamura, T. See Yamada, Kawamura, Gotohda, Ovary Cells, 1463 Vivo to Hyperthermia. 1130 Akiyama, Hosokawa, Kodama, and Kobayashi. Johnson, R. K. See Clement, Gorman, Wodinsky, Kan-Mitchell, J., Mitchell, M. S., Lin, T-S.. and 954 Catane, and Johnson. 4165 Prusoff, W. H. Comparative Analysis of the Im- Kawashima, Y. See Okada. Yamada. Kawashima, Joines, W. T. See Chang, Huang, and Joines, munosuppressive Properties of Two Antiviral, Kitade, Okajima. and Fujimoto. 1663

DECEMBER 1980 4851 Author Index to Volume 40

Kaye, C. I. See Rutzky, Kaye, Siciliano, Chao, and Whitehead and Kim, 29 azeff, and Hoppenstand, 64 Kahan, 1443 Kimball. J. C. See Wang. Madanat, Kimball. Kobata, A. See Yoshima, Mizuochi, Ishii, and Ko- Kaye, J.. Smith, C. A., and Hanawalt, P. C. DMA Gleiser, Ali, Kaufman, and van Eys, 1022 bata, 4276 Repair in Human Cells Containing Photoadducts Kimball, P. M., and Brattain, M. G. Isolation of a Kobayashi, H. See Minami, Kasai, Mizushima, of 8-Methoxypsoralen or Angelicin, 696 Cellular Subpopulation from a Human Colonie Takeichi, Hosokawa, and Kobayashi, 2129; Keating, M. J. See Plunkett, Hug, Keating, and Carcinoma Cell Line, 1574 Takeichi and Kobayashi, 448; Yamada, Kawa- Chubb, 588 Kimberly, P. J. See Newman, Kimberly, Stewart, mura, Gotohda, Akiyama, Hosokawa. Kodama, Keep, P. See Bagshawe, Searle, Lewis, Brown, and Kelley, 3621 and Kobayashi, 954 and Keep, 3016' Kimler, B. F. Effect of Dihydroxyanthraquinone Kobayashi, K. See Koji, Ishii, Munehisa, Kusu- Keijzer, W. See Hashem, Bootsma, Keijzer, and Radiation on G2 Progression. 42 moto, Nakamura, Tamenishi, HarÃ¡, Kobayashi, Greene, Coriell. Thomas, and Cleaver, 13 Kimura, N. T., Taniguchi, S., Aoki, K., and Baba, Tsukada. Nishi, and Hirai, 3013' Kelley, J. See Newman, Kimberly, Stewart, and T. Selective Localization and Growth of Bifido- Koch, M. R., Khalil, F. L., and Lea, M. A. De Kelley, 3621 bacterium bifidum in Mouse Tumors following creased Uptake of 14C-labeled Dicarboxylic Kelly, E. See Pleshkewych, Kramer, Kelly, and Intravenous Administration, 2061 Amino Acids in Rapidly Growing Hepatomas, Porter, 4533 Kinahan, J. J., Pavelic, Z. P., Leonard, R. J., 4053 Kelly, P. A. See Turcot-Lemay and Kelly, 3232 Bloch, A., and Grindey, G. B. Antitumor Activity Kochevar, I. E. See Sutherland, Harber, and Ko- Kemp, R. G. See Krishnaraj, Saat, and Kemp, of Cytidine Dialdehyde and Its Effects on Nu- chevar, 3181 2808 cleotide and Nucleic Acid Synthesis, 598 Kodama, T. See Gasa, Makita, Kameya, Kodama, Kempin, S. J. See Arlin, Sklaroff, Gee, Kempin, King, C. M. See Weeks, Allaben, Tresp, Louie, Araki, Yoneyama, Hirama, and Hashimoto, Howard, Clarkson, and Young, 3304 Lazear, and King, 1204 3804 Kennedy, A. R.. Murphy, G., and Little, J. B. King, G. M. See Balk, Hoon, King, Loskutoff, Kodama, T. See Yamada, Kawamura, Gotohda, Effect of Time and Duration of Exposure to 12- Mitchell, LeStourgeon, and Weselake, 1753 Akiyama, Hosokawa, Kodama, and Kobayashi, O-Tetradecanoylphorbol-13-acetate on X-Ray Kirkman, H. See Li, Li, Talley, Kirkman, Lin, and 954 Transformation of C3H 10T'/2 Cells, 1915 Villee, 3854 Koeffler. H. P., and Golde, D. W. Humoral Mod Kennedy, K. A., Rockwell, S., and Sartorelli, A. Kirkwood, J. M., Ensminger, W., Rosowsky, A., ulation of Human Acute Myelogenous Leukemia C. Preferential Activation of Mitomycin C to Cy- Papathanasopoulos, N., and Frei, E., Ill Com Cell Growth in Vitro, 1858 totoxic Metabolites by Hypoxie Tumor Cells, parison of Pharmacokinetics of 5-Fluorouracil Koeffler, H. P., Golde, D. W., and Lippman, M. 2356 and 5-Fluorouracil with Concurrent Thymidine E. Glucocorticoid Sensitivity and Receptors in Kennel, S. J., Lankford, P. K., Foote, L. J., Tsak- Infusions in a Phase 1 Trial, 107 Cells of Human Myelogenous Leukemia Lines, eres, F. S., Adams, L. M., and Ullrich, R. L. Kirsh, R. See Fidler, Raz, Fogler, Kirsh, Bugelski, 563 Distribution of a Tumor Cell Surface Protein and Poste, 4460 Koehler, B. See Yuspa. Hawley-Nelson, Koehler, Common to Several Murine Lung Carcinomas, Kishishita, M. See Ito, Kishishita, and Vanase. and Stanley, 4694 2153 4329 Koessler, A. See Taetle and Koessler, 1223 Kerns, W. D. See Swenberg, Kerns, Mitchell, Kishore, G. S. See DiGiovanni, Berry, Gleason, Kohler, P. 0. See Siciliano. Bordelon-Riser, Gralla, and Pavkov, 3398 Kishore, and Slaga, 1580 Freedman. and Kohler, 283 Keski-Oja, J., and Todaro, G. J. Specific Effects Kissonerghis, A-M. See Coombs, Bhatt, Kisso- Kohn, K. I. See Kessel and Kohn, 303 of Fibronectin-Releasing Peptides on the Extra nerghis. and Vose, 882 Kohn, K. W. See Bradley, Sharkey, Kohn, and cellular Matrices of Cultured Human Fibroblasts, Kitade, F. See Okada, Yamada, Kawashima, Ki- Layard, 2719; Erickson, Ramonas, Zaharko, 4722 tade. Okajima, and Fujimoto, 1663 and Kohn, 4216 Kessel, D. Cell Surface Alterations Associated Kitagawa, T. See Ishikawa, Takayama, and Kita- Koizumi, K., Tamiya-Koizumi, K., Fujii, T., with Exposure of Leukemia L1 210 Cells to Fluo- gawa, 4261 Okuda, J., and Kojima, K. Comparative Study rouracil, 322 Kitamura, Y., Uchida, N., Hayata, I., Yamaguchi, of the Phospholipid Composition of Plasma Kessel, D., and Kohn, K. I. Transport and Binding K., Okamoto, S., Marita, N., and Matsumoto, Membranes Isolated from Rat Primary Hepato of Mesoporphyrin IX by Leukemia L1210 Cells. K. Effect of Serial Passage in Female Nude mas Induced by 3'-Methyl-4-dimethylaminoaz- 303 Athymic Mice on Androgen-dependency of obenzene and from Normal Growing Rat Livers, Kessel, D., Shah-Reddy, L, Mirchandani, I., Khi- Shionogi Carcinoma 115, page 4781 909 lanani, P., and Chou, T-H. Electrofocusing Pat Kitamura, Y., Yokoyama, M., Matsuda, H., and Koji, T., Ishii, N., Munehisa, T., Kusumoto, Y., terns of Fucosyltransferase Activity in Plasma of Shimada, M. Coincidental Development of Fore- Nakamura, S., Tamenishi, A., Hara, A., Kobay Patients with Chronic Granulocytic Leukemia, stomach Papilloma and Prepyloric Ulcer in Non- ashi, K., Tsukada, Y., Nishi, S., and Hirai, H. 3576 treated Mutant Mice of W/W and S) /Si " Gen Localization of Radioiodinated Antibody to a- Kessler, A. See Rahman, Kessler, More, Sikic, otypes, 3392 Fetoprotein in Hepatoma Transplanted in Rats Rowden, Woolley, and Schein. 1532 Kitao, T., and Hattori, K. Erythrocyte Entrapment and a Case Report of a-Fetoprotein Antibody Kessous. A., Colombies, P., Pris, J., and Clem of Daunomycin by Amphotericin B without He- Treatment of a Hepatoma Patient, 3013* ent, D. Near Haploid Cell Line in Lymphoid Blast molysis, 1351 Kojima, K. See Koizumi, Tamiya-Koizumi, Fujii, Crisis of Ph'-positive Chronic Myeloid Leuke Kiyohara, T. See Yoshida, Kiyohara, Fukui, At- Okuda, and Kojima. 909 mia, 1354 sumi, Ogino, Inaba, Tsukagoshi. and Sakurai, Komatsu, H. See Kakizoe, Komatsu, Niijima, Ka- Khalil, F. L. See Koch, Khalil, and Lea, 4053 3810 wachi, and Sugimura, 2006 Khan, 0. See Ell and Khan, 3059' Kizaki, H., Morris, H. P., and Weber, G. Behavior Kopelman, R. See Marcus and Kopelman. 1014 Khan, S., Feldman, M., and Hollander, V. P. The of Inosine Phosphorylase (EC 2.4.2.1) Activity Kopf, A. W. See Bart, Porzio, Kopf, Vilcek, Cheng, Biological Significance of Estradiol Receptor in Normal, Differentiating, and Regenerating and Farcet, 614 Binding to DNA, 1050 Liver and in Hepatomas, 3339 Kopiwoda, S. See Castronovo. Potsaid, and Ko- Khilanani, P. See Kessel. Shah-Reddy. Mirchan Kizaki, H., Williams, J. C., Morris, H. P., and piwoda, 3473 dani, Khilanani, and Chou, 3576 Weber, G. Increased Cytidine 5'-Triphosphate Koplitz, M. See Clawson, Koplitz. Moody, and Kibert, L. See Short, Klein, Kibert, and Ove, 2417 Synthetase Activity in Rat and Human Tumors, Smuckler. 75 Killian, C. S. See Kuriyama. Wang, Papsidero, 3921 Koplitz, R. M. See Tkeshelashvili, Shearman, Zak- Killian. Shimano, Valenzuela, Nishiura, Murphy, Klein, G. See Spira, Babonits, Wiener, Ohno, Wir- our, Koplitz, and Loeb, 2455 and Chu, 4658 schubski, Haran-Ghera, and Klein, 2609 Koprak, S. See Diammond, Koprak, and Hol Kim, E. E. See DeLand, Kim, and Goldenberg, Klein, J. L. See Order, Klein, Ettinger, Alderson, lander, 1091 2997'; DeLand, Kim, Simmons, and Golden- Siegelman, and Leichner, 3001 â€¢ Koprowski, H. See Herlyn, Clark, Mastrangelo. berg, 3046'; Goldenberg, Kim. DeLand. Ben Klein, K. See Short, Klein, Kibert. and Ove, 241 7 Guerry, Elder, LaRossa, Hamilton. Bondi. Tuth- nett, and Primus, 2984'; Primus, Bennett, Kim, Kleinerman, E. S., Zwelling, L. A., and Much- Â¡II.Steplewski, and Koprowski, 3602; Herlyn, DeLand. Zahn, and Goldenberg. 497; van Na- more, A. V. Enhancement of Naturally Occur Steplewski, Herlyn, and Koprowski, 717 gell, Kim, Casper, Primus, Bennett, DeLand, ring Human Spontaneous Monocyte-mediated Koreeda, M. See Wood, Levin, Chang, Huang, and Goldenberg, 502 Cytotoxicity by c/s-Diamminedichloroplati- Ryan. Thomas, Lehr, Kumar, Koreeda, Akagi, Kim, E. E., DeLand, F. H., Nelson, M. O., Bennett, num(ll), 3099 Ittah, Dansette, Yagi, Jerina, and Conney, 642 S., Simmons, G., Alpert, E., and Goldenberg, Kligman, L. See Lin, Kligman, and Farber, 3755 Kosaki, G. See Ohtsuru, Ishii, Takai, Higashi, and D. M. Radioimmuodetection of Cancer with Ra Klootwijk-van Dijke, E. See de Both. Kwak. and Kosaki, 477 diolabeled Antibodies to a-Fetoprotein, 3008' Klootwijk-van Dijke, 4270 Kost, T. A., Hankins, W. D., Click, A. D., and Kim, J. H. See Kim, Kim, Hahn, and Ensign, 3459 Knauer, D. J., Iyer, A. P., Banerjee, M. R., and Krantz, S. B. Production of Spleen Focus-form Kim, S. H., Kim, J. H.. Hahn, E. W., and Ensign, Smith, G. L. Identification of Somatomedin-like ing Virus and Murine Leukemia Virus by Early N. A. Selective Killing of Glucose and Oxygen- Polypeptides Produced by Mammary Tumors of Erythroblasts after Friend Virus Infection. 1150 Kouri, R. E. See Nayar, Levy. O'Neill, and Kouri, deprived HeLa Cells by Hyperthermia, 3459 BALB/c Mice, 4368 Kim, Y. S. See Freeman. Spiller, and Kim. 2661; Kniazeff, A. J. See Theiss, Shimkin, Stoner. Kni- 4364

4852 CANCER RESEARCH VOL. 40 Author Index to Volume 40

Kozai, Y. See Ootsu, Kozai, Takeuchi, Ikeyama, induced Mutation and Mitotic Recombination in Langenbach, R., Gingell, R., Kuszynski, C., Igarashi, Tsukamoto, Sugino, Tashiro, Tsuka- Saccharomyces cerevisiae, 2323 Walker, B., Nagel, D., and Pour, P. Mutagenic goshi, and Sakurai, 1707 Kurashige, S. See Miura. Nogiwa. Kurashige. and Activities of Oxidized Derivatives of N-Nitroso- Kraft, P. L., Skipper, P. L., and Tannenbaum, S. Maekawa, 4813 dipropylamine in the Liver Cell-mediated and R. In Vivo Metabolism and Whole-Blood Clear Kurisaki, E. See Nakata. Ochi, Kurisaki, Okano. Salmonella typhimurium Assays, 3463 ance of W-Nitrosomethylbenzylamine in the Rat, Hamada, Amitani, Tanabe, Ono, and Sakamoto, Lankford, P. K. See Kennel, Lankford, Foote, 2740 127 Tsakeres, Adams, and Ullrich, 2153 Kraft, P. L., and Tannenbaum, S. R. Distribution Kurisu, M., Yamazaki, M., and Mizuno, D. Induc Lannin, D. R. See Yu, Lannin, Tsui-Collins, and of N-Nitrosomethylbenzylamine Evaluated by tion of Macrophage-mediated Tumor Lysis by McKhann, 2756 Whole-Body Radioautography and Densitome- the Lectin Wheat Germ Agglutinin, 3798 LaRossa, 0. See Herlyn, Clark. Mastrangelo, try, 1921 Kuriyama, M., Wang, M. C., Papsidero, L. D., Guerry, Elder. LaRossa, Hamilton. Bondi. Tuth- Krahenbuhl, J. L. Effects of Activated Macro Killian, C. S., Shimano, T., Valenzuela, L., ill. Steplewski, and Koprowski. 3602 phages on Tumor Target Cells in Discrete Nishiura, T., Murphy, G. P., and Chu, T. M. Laskin, D. L., Laskin, J. D., Weinstein, I. B., and Phases of the Cell Cycle, 4622 QuantitÃ¤ten of Prostate Specific Antigen in Se Carchman, R. A. Modulation of Phagocytosis Kramer, D. L. See Pleshkewych, Kramer, Kelly, rum by a Sensitive Enzyme Immunoassay. 4658 by Tumor Promoters and Epidermal Growth and Porter, 4533 Kuroki, M. See Watanabe, Shimosato. Kuroki, Factor in Normal and Transformed Macro Kramer, R. J. See Dittman, Kramer, and Bainton, Sato, and Nakajima, 2588 phages, 1028 4473 Kusumoto, Y. See Koji, Ishii, Munehisa, Kusu- Laskin, J. D. See Evans. Laskin, and Hakala. Krance, R. A. See Jackson, Krance, Edwards, moto, Nakamura, Tamenishi, HarÃ¡, Kobayashi, 4113; Laskin, Laskin, Weinstein, and Carch Whidden, and Gauthier, 667 Tsukada, Nishi, and Mirai, 3013* man, 1028 Krantz, S. B. See Kost, Hankins, Glick, and Kuszynski, C. See Langenbach. Gingell, Kuszyn- Laurent, G., Dewerie-Vanhouche, J., Machin, D., Krantz, 1150 ski, Walker, Nagel, and Pour, 3463 and Hildebrand, J. Inhibition of RNA Synthesis Kreis, W., Baker, A., Ryan, V., and Bertasso, A. Kwak, E. See de Both, Kwak, and Klootwijk-van in Murine Ependymoblastoma by the Combina Effect of Nutritional and Enzymatic Methionine Dijke, 4270 tion of Amphotericin B and 1-{2-Chloroethyl>-3- Deprivation upon Human Normal and Malignant Kyriazis, A. A., and Kyriazis, A. P. Preferential cyclohexyl-1-nitrosourea. 939 Cells in Tissue Culture, 634 Sites of Growth of Human Tumors in Nude Mice Lavis, V. R. See Thompson. Ross. Strada. Hersh, Kretzer, F. See Asch, Medina, Kretzer, Connolly, following Subcutaneous Transplantation, 4509 and Lavis. 1955 and Brinkley. 2383 Kyriazis, A. P. See Kyriazis and Kyriazis, 4509 LaVoie, E. J., Hecht, S. S., Amin, S., Bedenko, Kripke, M. L., and Fidler, I. J. Enhanced Experi V., and Hoffmann, D. Identification of Muta mental Metastasis of Ultraviolet Light-induced genic Dihydrodiols as Metabolites of Fibrosarcomas in Ultraviolet Light-irradiated Benzo(j)fluoranthane and Benzo(k)fluoran- Syngeneic Mice, 625 thene, 4528 Krishan, A. See Ganapathi and Krishan, 1103; LaBrosse, E. H., Com-Nougue. C., Zucker, J-M., Lavrovsky, V. A., and Viksler, V. K. Immunologi- Ganapathi, Krishan, Wodinsky, Zubrod, and Comoy, E., Bohuon, C., Lemerle, J., and cai Properties of Malignant and Nonmalignant Lesko, 630 Schweisguth, O. Urinary Excretion of 3-Me- Sublines of L-Cells, 3252 Krishan, A., and Ganapathi, R. Laser Flow Cy- thoxy-4-hydroxymandelic Acid and 3-Methoxy- Law, L. W. See DuBois. Appella. Law, DeLeo, and tometric Studies on the Intracellular Fluores 4-hydroxyphenylacetic Acid by 288 Patients Old, 4204 cence of Anthracyclines, 3895 with Neuroblastoma and Related Neural Crest Lawrence, W. D., Shingleton, H. M., Gore, H., Krishnamurti, C., Saryan, L. A., and Petering, D. Tumors, 1995 and Soong, S-J. Ultrastructural and Morpho- H. Effects of Ethylenediaminetetraacetic Acid Laburthe, M., Rousset, M., Chevalier, G., Bois- metric Study of Diethylstilbestrol-associated Le and 1,10-Phenanthroline on Cell Proliferation sard, C., Dupont, C., Zweibaum, A., and Ros- sions Diagnosed as Cervical Intraepithelial Neo and DNA Synthesis of Ehrlich Ascites Cells, selin, G. Vasoactive Intestinal Peptide Control plasia III, 1558 4092 of Cyclic Adenosine 3':5'-Monophosphate Lev Lawson, D. H. See Chawla, Lawson. Richmond, Krishnaraj, R., Saat, Y. A., and Kemp, R. G. els in Seven Human Colorectal Adenocarcinoma and Rudman, 4187; Chawla. Shlaer, Lawson, Binding of Monosialoganglioside by Murine Thy Cell Lines in Culture, 2529 Murray, Schmidt, Shoji. Nixon, Richmond, and mus Cells in Vitro, 2808 Laine, B. M. See Hitchins, Laine, and Hutton, 424 Rudman. 3915 Kruizinga, W. See Ramselaar, Ruitenberg, and Laishes, B. A., and Rolfe, P. B. Quantitative As Lawson, T. See Pour, Gingell, Langenbach, Na Kruizinga, 1668 sessment of Liver Colony Formation and Hepa- gel, Grandjean, Lawson, and Salmasi, 3585 Kruuv, J. See Lepock and Kruuv, 4485 tocellular Carcinoma Incidence In Rats Receiv Layard, M. W. See Bradley, Sharkey, Kohn, and Kuettner, K. E. See Pauli, Anderson, Memoli, and ing Intravenous Injections of Isogenic Liver Cells Layard, 2719 Kuettner, 4571 Isolated During Hepatocarcinogenesis. 4133 Lazear, E. J. See Weeks, Allaben, Tresp, Louie, Kufe, D. W. See Nadler, Stashenko. Hardy, Ka Lalanne, C. See Namer, Lalanne, and Baulieu. Lazear, and King. 1204 plan, Button, Kufe, Animan, and Schlossman, 1750 Lea, M. A. See Koch, Khalil, and Lea, 4053 3147 Lam, H-Y. P., Talgoy, M. M., and Goldenberg, G. Leavens, M. See Stewart. Benjamin, Leavens, KÃ¼hn,J. See Von Hoff, Pollard, KÃ¼hn,Murray, J. The Uptake and Decomposition of Chlorozo- Valdivieso, Burgess, and Bodey, 3750; Stewart, and Coltman, 1516 tocin in L5178Y Lymphoblasts in Vitro, 3950 Leavens, Friedman, Benjamin, Moore, Bodey, Kuhns, W. J., Oliver, R. T. D., Watkins, W. M., Lam, L. K. T. See Wattenberg. Coccia, and Lam. Valdivieso, Burgess, Wiseman, and Loo, 3163 and Greenwell, P. Leukemia-induced Altera 2820 Leboy. P. S. See Brunke, Strickler, and Leboy, tions of Serum Glycosyltransferase Enzymes. Lam, L. K. T., Fladmoe, A. V., Hochalter, J. B., 417 268 and Wattenberg, L. W. Short Time Interval Ef Lechner, J. F. See Ohnuki, Mameli. Babcock. Kulkarni, M. S., Heidepriem, P. M., and Yielding, fects of Butylated Hydroxyanisole on the Metab Lechner, and Kaighn, 524 K. L. Production by Lithocholic Acid of DNA olism of Benzo(a)pyrene, 2824 Lee, C-l.. Murphy, G. P., and Chu, T. M. Purifi Strand Breaks in L1210 Cells, 2666 Lampidis, T. J., Henderson, I. C., Israel, M., and cation and Characterization of Acid Phospha- Kumagai, N. See Morizane, Kumagai, Tsuchi- Canellos. G. P. Structural and Functional Ef tase from Dunning R3327H Prostatic Adenocar moto, Watanabe, and Tsuchiya, 2928 fects of Adriamycin on Cardiac Cells in Vitro, cinoma, 1245 Kumar, P., Kumar, S., Marsden, H. B., Lynch, P. 3901 Lee, G. See Tsuda, Lee, and Farber, 1157 G., and Earnshaw, E. Weibel-Palade Bodies in Lando, P., Blomberg, F., Berzins, K., and Perl- Lee, H. M. See Slaga, Gleason. Mills, Ewald, Fu, Endothelial Cells as a Marker for Angiogenesis mann, P. Tumor-associated Cytotoxicity of Lee, and Harvey, 1981 in Brain Tumors, 2010 Autoantibodies in Sera from Rats with Chemi Lee, I. P., and Nagayama, J. Metabolism of Kumar, S. See Kumar, Kumar, Marsden, Lynch, cally-induced Hepatomas, 1691 Benzo(a)pyrene by the Isolated Perfused Rat and Earnshaw. 2010 Landolph. J. R., Bhatt, R. S., Telfer, N., and Testis, 3297 Kumar, S. See Wood, Chang, Huang, Levin, Lehr, Heidelberger, C. Comparison of Adriamycm- Lee, I. P., Suzuki, K., Mukhtar, H., and Bend, J. Kumar, Thakker, Yagi, Jerina, and Conney, and Ouabain-induced Cytotoxicity and Inhibition R. Hormonal Regulation of Cytochrome P-450- 1985; Wood, Levin, Chang, Huang. Ryan, of 86Rubidium Transport in Wild-Type and Oua- dependent Monooxygenase Activity and Epox- Thomas. Lehr, Kumar, Koreeda. Akagi, Ittah, bain-resistant C3H/10TV4 Mouse Fibroblasts, ide-metabolizing Enzyme Activities in Testis of Dansette, Yagi, Jerina, and Conney, 642 4581 Hypophysectomized Rats, 2486 Kung, W. M., Geyer, E., Eppenberger, U., and Lane, B. P. See Gordon and Lane, 4467 Lee, J. Y. See Meyer and Lee. 1890 Huber, P. R. Quantitative Estimation of Cellular Lange, G. W. See Loewenstein, Lange, and Ger Lee, N. F. See Yoo. ChiÃ¹, Spector, Whiteaker, Retinoic Acid-Binding Protein Activity in Normal, ard, 4398 Denning, and Lee. 1084 Dysplastic and Neoplastic Human Breast Tis Lange, P. H. See Bronson. Andrews. Solter, Cer- Lee, R. E. See Petrakis. Maack, Lee, and Lyon, sue. 4265 venka, Lange, and Fraley, 2500 188 Kunz, B. A., Hannan, M. A., and Haynes, R. H. Langenbach, R. See Pour, Gingell, Langenbach. Lee, S. S., Giovanella, B. C., Stehlin, J. S., and Effect of Tumor Promoters on Ultraviolet Light- Nagel. Grandjean, Lawson, and Salmasi, 3585 Howell, S. B. Correspondence re: S. B. Howell,

DECEMBER 1980 4853 Author Index to Volume 40

R. S. Jenkins, and J. Streifel. Activity of Thymi- and Keep, 3016- Lombard, Stevens, and Fry, 3268 dine as a Chemotherapeutic Agent against Hu Leyva, A. See Buesa-Perez, Leyva, and Pinedo, Lombardi, B. See Shinozuka and Lombardi, 3846 man Tumor Xenografts in Nude Mice. Cancer 139 Londer, H. See Speyer, Collins, Dedrick, Brennan, Res., 39. 3875-3880, 1979, page 1764, Letter Lhoste, J-M. See Perin-Roussel, Croisy-Delcey, Buckpitt, Londer, DeVita, and Myers, 567 to the Editor Mispelter, Saguem, Chalvet, Ekert, Fouquet, Long, C. W., Bruszewski, J. A., and Snead, R. Lehman, C. See Grant. Lehman, and Cadman, Jacquignon, Lhoste, Muel, and Zajdela, 1742 M. Analysis of Transcription during Type C Viral 1525 Li, G. C., and Hahn, G. M. A Proposed Operational Induction Using Cell Permeabilization Tech Lehr, R. E. See Buening, Levin, Wood, Chang, Model of Thermotolerance Based on Effects of niques, 22 Lehr, Taylor, Yagi, Jerina, and Conney, 203; Nutrients and the Initial Treatment Temperature, Long, C. W., Suk, W. A., Snead, R. M., and Wood, Chang, Huang, Levin, Lehr, Kumar, 4501 Christensen, W. L. Cell Cycle-Specific En Thakker, Yagi, Jerina, and Conney, 1985; Li, J. J., Li, S. A., Talley, D. J., Kirkman, H., Lin, hancement of Type C Virus Activation by So Wood, Levin, Chang, Huang, Ryan, Thomas, Y. C., and Villee, C. A. Correspondence re: dium n-Butyrate, 3886 Lehr, Kumar, Koreeda, Akagi, Utah, Danserte, Young C. Lin, Deanna J. Talley, and Claude A. Lonn, S. See LÃ¶nnand Lonn, 3792 Yagi, Jerina, and Conney, 642 Villee. Increased Progesterone Receptor Con LÃ¶nn, U-, and LÃ¶nn,S. Double-Stranded DNA Leibson, P. J., Loken, M. R., Shapiro, S. J., and centrations in Bladder Lesions of Estrogen- Replication Intermediates in Human Malignant Schreiber, H. Direct Determination of the Influ treated Syrian Hamsters. Cancer Res., 39: Melanoma Cells, 3792 ence of the Cell Cycle on the Survival of Tumor 2614-2617, 1979, page 3854, Letter to the Loo, T. L. See Lu and Loo, 1427; Stewart, Leav Cells Exposed to Cytotoxic Antibodies, 56 Editor ens, Friedman, Benjamin, Moore, Bodey, Val Leichner, P. See Order, Klein, Ettinger, Alderson, Li, S. A. See Li, Li, Talley, Kirkman, Lin, and divieso, Burgess, Wiseman, and Loo, 3163 Siegelman, and Leichner, 3001 * Villee, 3854 Loo, T. L., Friedman, J., Moore, E. C., Valdivieso, Leith, J. See Miller, Miller, Leith. and Heppner, Liang, J. C., Gaulden, M. E., and Herndon, J. H., M., Marti, J. R., and Stewart, D. Pharmacolog 3977 Jr. Chromosome Markers and Evidence for ical Disposition of N-(Phosphonacetyl>-L-aspar- Lemerle, J. See LaBrosse, Com-NouguÃ©,Zucker, Clone Formation in Lymphocytes of a Patient tate in Humans, 86 Comoy, Bohuon, Lemerle, and Schweisguth, with SÃ©zarySyndrome, 3426 Looney, W. B., Ritenour, E. R., and Hopkins, H. 1995 Lieberman, M. See Boniver, DeclÃ¨ve,Finn, Hon- A. Changes in Growth Rate of an Experimental Lenhart, G. See Rogers, Lenhart, and Morrison, sik, Lieberman, and Kaplan, 544 Solid Tumor following Increasing Doses of Cy- 2802 Lijinsky, W. See Cardy and Lijinsky, 1879; Rez- clophosphamide, 2179 Leonard, R. J. See Kinahan, Pavelic, Leonard, nik-Schuller, Lijinsky, and Hague, 2245 Loskutoff, D. See Balk, Hoon, King, Loskutoff, Bloch, and Grindey, 598 Lijinsky, W., and Reuber, M. D. Carcinogenicity Mitchell, LeStourgeon, and Weselake, 1753 Leong, S. S. See Papsidero, Wojcieszyn, Horo- in Rats of Nitrosomethylethylamines Labeled Lotan, D. See Lotan and Lotan, 3345; Lotan, szewicz, Leong, Murphy, and Chu, 3032* with Deuterium in Several Positions, 19 Neumann, and Lotan. 1097 Lepock, J. R., and Kruuv, J. Thermotolerance as Lijinsky, W., Saavedra, J. E., Reuber, M. 0., and Lotan, R., and Lotan, D. Stimulation of Melano- a Possible Cause of the Critical Temperature at Blackwell, B. N. Carcinogenicity of 3-Chloroni- genesis in a Human Melanoma Cell Line by 43Â°in Mammalian Cells, 4485 trosopiperidine, 4-Chloronitrosopiperidine, and Retinoids, 3345 Leserman, L. D., Weinstein, J. N., Moore, J. J., 3,4-Dichloronitrosopiperidine in Fischer Rats, Lotan, R., Neumann, G., and Lotan, D. Relation and Terry, W. D. Specific Interaction of Mye 3325 ships among Retinoid Structure, Inhibition of loma Tumor Cells with Hapten-Bearing Lipo Lilga, J. C. See Stinson and Lilga, 609 Growth, and Cellular Retinole Acid-binding Pro somes Containing Methotrexate and Carboxy- Lin, J-C-, Kligman, L., and Farber, E. Purification tein in Cultured S91 Melanoma Cells, 1097 fluorescein, 4768 and Partial Characterization of a Preneoplastic Louie, S. C. See Weeks, Allaben, Tresp, Louie, Lesko, L. J. See Ganapathi, Krishan. Wodinsky. Antigen in Liver Carcinogenesis, 3755 Lazear, and King, 1204 Zubrod, and Lesko, 630 Lin, T-S. See Kan-Mitchell, Mitchell, Lin, and Pru- Louis, J. See Greenberg, Caruana, Holcomb, LeStourgeon, D. N. See Balk, Hoon, King, Los- soff, 3491 Greenberg, Parker, Louis, and White, 439 kutoff, Mitchell, LeStourgeon, and Weselake, Lin, Y. C. See Li, Li, Talley, Kirkman, Lin, and Lu, A. Y. H. See Wislocki, Gadek, Chou, Yang, 1753 Villee, 3854 and Lu, 3661 Leung, F. C. See Aylsworth, Sylvester, Leung, Lindner, D. J. See Tew, Schein, Lindner, Wang, Lu, K., and Loo, T. L. Pharmacological Disposi and Meites, 1863 and Smulson, 3697 tion of 1,4-Bis{2-{(2-hydroxyethyl)amino]-eth- Leung, J. P., and Edgington, T. S. Radioimmu- Liotta, L. See Murray, Liotta, Rennard, and Mar ylamino)-9,10-anthracenedione Diacetate in noassay for Tissue Distribution of a Human tin, 347 the Dog, 1427 Mammary Tumor-specific Glycoprotein, 662; Lippman, M. E. See Chong and Lippman, 3172; Lu, L-J. W., and Randerath, K. Mechanism of 5- Subcellular Localization of the Sedimentable DeWys, Allegra, Simon, and Lippman, 2423; Azacytidine-induced Transfer RNA Cytosine-5- Form of Mammary Tumor Glycoprotein to the Everson, Lippman, Thompson, McGuire, Wittliff, methyltransferase Deficiency, 2701 Tumor Cell Plasmalemma, 316 De Sombre, Jensen, Singhakowinta, Brooks, Lubich, W. P. See Fulton, Levin, Lubich, Wilson, Levi, V. See Jacobson, Levi, Juarez-Salinas, Bar and Neifeld, 991 ; Koeffler, Golde, and Lippman, and Marlon, 3293 ton, and Jacobson, 1797 563 Lucas, Z. J. See Huber, Bigi, and Lucas, 3477, Levin, M. J. See Siber, Mayer, and Levin, 3430 Little, B. See Heintz, Little, Bresnick, and Schaef- 3484 Levin, V. A. See Fulton, Levin, Lubich, Wilson, fer, 1281 Ludlum, D. B. See Merita, Przybylski, and Ludlum, and Marlon, 3293 Little, J. B. See Kennedy, Murphy, and Little, 4183 Levin, W. See Buening, Levin, Wood, Chang, 1915; Weichselbaum, Nove, and Little, 920; Lui, M. S. See Jackson, Lui, Boritzki, Morris, and Lehr, Taylor, Yagi, Jerina, and Conney, 203; West, Weichselbaum, and Little, 3665 Weber, 1286; Olah, Lui, Tzeng, and Weber, Wood, Chang, Huang, Levin. Lehr, Kumar, Litwack, G. See Smith, Ohi, and Litwack, 1787 2869 Thakker, Yagi. Jerina, and Conney. 1985; Liu, A. Y-C., Fiske, W. W., and Chen, K. Y. Lund, J. K. See Ashley, Cardiff, Mitchell, Faulkin. Wood, Chang, Levin, Ryan, Thomas, Croisy- Regulation of Cyclic Adenosine 3':5'-Mono- and Lund, 4232; Drohan, Cardiff, Lund, and Delcey, Ittah, Yagi, Jerina, and Conney, 2876; phosphate-binding Protein in N-18 Mouse Neu Schlom, 2316 Wood, Levin, Chang, Huang, Ryan, Thomas, roblastoma Cells. 4100 Lundholm, K., EdstrÃ¶m,S., Karlberg, I., Ekman, Lehr, Kumar, Koreeda, Akagi, Ittah, Dansette, Livingston, R. B. See Osborne, Hamilton, Titus, L., and ScherstÃ©n,T. Relationship of Food In Yagi, Jerina, and Conney, 642 and Livingston, 2361 take, Body Composition, and Tumor Growth to Levin, W., Wood, A. W., Chang, R. L., Ittah, Y., Livingston, R. B., Titus, G. A., and Heilbrun, L. Host Metabolism in Nongrowing Mice with Sar Croisy-Delcey, M., Yagi, H., Jerina, D. M., and K. In Vitro Effects on DNA Synthesis as a Pre coma, 2516 Conney, A. H. Exceptionally High Tumor-initi dictor of Biological Effect from Chemotherapy, Lundholm, K., Ekman, L., Karlberg, l., EdstrÃ¶m, ating Activity of Benzo(c)phenanthrene Bay-Re 2209 S., and ScherstÃ©n,T. Comparison of Hepatic gion Diol Epoxides on Mouse Skin, 3910 Loeb, L. A. See Tkeshelashvili, Shearman, Zak- Cathepsin D Activity in Response to Tumor Levine, E. M. See Baird, Chemerys, Grinspan, our, Koplitz, and Loeb, 2455 Growth and to Caloric Restriction in Mice, 1680 Mueller, and Levine. 1781 Loehrke, H. See Goerttler, Loehrke, Schweizer, Lutz, H., Pedersen, N., Higgins, J., HÃ¼bscher,U., Levitt, D. S. See Johnson, Levitt, Muller-Eberhard, and Hesse, 155 Troy, F. A., and Theilen, G. H. Humoral Immune and Thorgeirsson, 4456 Loewenstein, P. M., Lange, G. W., and Gerard, Reactivity to Feline Leukemia Virus and Asso Levitt, S. H. See Kang, Song, and Levitt, 1130 G. F. Distribution of DNA Polymerase Cm in ciated Antigens in Cats Naturally Infected with Levy, H. M. See Hann, Levy, and Evans, 1411 Normal and Malignant Human Tissues, 4398 Feline Leukemia Virus, 3642 Levy, J. A. See Nayar, Levy, O'Neill, and Kouri, Lohman, P. H. M. International Commission for Lyga, J. W. See Iyer, Lyga, Secrist. Daub, and 4364 Protection against Environmental Mutagens and Slaga, 1073 Lewinski, C. See Trown, Palleroni, Bohoslawec, Carcinogens, 186, Letter to the Editor Lynch, P. G. See Kumar, Kumar, Marsden, Lynch, Richelo, Halpern, Gizzi, Geiger, Lewinski, Loken, M. R. See Leibson, Loken, Shapiro, and and Earnshaw, 2010 Machlin, Jetten, and Jetten, 212 Schreiber, 56 Lyon, l. See Kannan, Lyon, and Baker, 4606 Lewis, J. See Bagshawe, Searle, Lewis, Brown, Lombard, L. S. See Peraino, Staffeldt, Haugen, Lyon, M. See Petrakis, Maack, Lee, and Lyon,

4854 CANCER RESEARCH VOL. 40 Author Index to Volume 40

188 Wang, McLoughlin, Richie, and Mannick, 288; K., and Ishida, N. Isolation of an Inhibitor of Lysik, R. See DiStefano, Beck. Lysik, and Zucker, Yang. Steele, Wang, and Mannick, 1762 Type II Interferon Induction from Tumor Ascitic 1372 Marcus, S. L., and Kopelman, R. Poly(2'-O-meth- Fluids, 2534 ylcytidylate)-directed DMA Polymerase and Ter Matsuda, H. See Kitamura, Yokoyama. Matsuda, minal Deoxynucleotidyltransferase Activities in and Shimada, 3392 Maack, C. A. See Petrakis, Maack, Lee. and Lyon. Particulate Fractions Obtained from Human Matsui, S-i. See Wake. Hreshchyshyn. Piver. Mat- 188 Spleens, 1014 sui, and Sandberg, 4512 Macdonald, J. See Ardalan, Cooney, Jayaram. Mareel, M. M. See Storme and Mareel, 943 Matsukura, S., Kakita, T., Sueoka, S., Yoshimi, Carrico. Glazer, Macdonald, and Schein, 1431; Margison, G. P. See Montesano, BrÃ©sil,Planche- H., Mirata, Y., Yokota, M., and Fujita, T. Multi Mori, Jasmin, Hayat, Macdonald, and Mathe, Martel. Margison, and Pegg. 452 ple Hormone Receptors in the Adenylate Cy- 4282 Margolis, V. B. See Broxmeyer. Ralph. Gilbertson. clase of Human Adrenocortical Tumors, 3768 Mace, M. L. See Brinkley, Beali, Wible. Mace, and Margolis. 3928 Matsumoto, K. See Kitamura, Uchida, Hayata, Turner, and Cailleau, 3118 Marie, J. P. See Homo. Duval. Harousseau. Marie, Yamaguchi, Okamoto. Manta, and Matsumoto, MacEwen, E. G. See Gordon, Moroff, Hurvitz, and Zittoun, 2601 4781 Matus, MacEwen, Good, and Day, 3627 Mannello, A. J. See Gurtoo. Vaught, Mannello, Matsumura. K. See Shors, Fu, Matsumura, Mach, J-P. See Carrel, Accolla, Carmagnola, and Paigen, Gessner, and Bolanowska, 1305 Cohen, and Benfield, 2288 Mach. 2523 Markland, F. S., Jr. See Hawkins, Horn, and Matsushima, M., and Bryan, G. T. Early Induction Machin, D. See Laurent, Dewerie-Vanhouche, Ma Markland, 2174 of Mouse Urinary Bladder Ornithine Decarbox- chin, and Hildebrand, 939 Marks, A. See Baumal, Marks, Mahony, and Bose, ylase Activity by Rodent Vesical Carcinogens. Machlln, L. J. See Trown, Palleroni, Bohoslawec. 1630 1897 Rlchelo, Halpern, Gizzi, Geiger, Lewinski, Markus, G., Takita, H., Camiolo, S. M., Cora- Matsushima, T. See Saito, Sawamura, Umezawa, Machlin, Jetten, and Jenen, 212 santi, J. G., Evers, J. L., and Hobika, G. H. Kanai. Furihata. Matsushima. and Sugimura, Maclntyre, I. See Findlay, Michelangeli. Eisman. Content and Characterization of Plasminogen 2539; Tohda, Horaguchi. Takahashi, Oikawa, Frampton, Moseley, Maclntyre, Whitehead, and Activators in Human Lung Tumors and Normal and Matsushima, 4775 Martin, 4764 Lung Tissue, 841 Matsuzawa, A., Mizuno, Y., Yamamoto, T., Mori, MacLeod, M. C. See Cohen, MacLeod. Moore, Marlowe, C. See Waddell and Marlowe. 3518 T., and Suzuki, T. Cytoplasmic Estrogen Re and Selkirk, 207 Mameli, M. M. See Ohnuki. Mameli. Babcock. ceptor in a Pregnancy-dependent Mouse Mam Macnab, J. C. M., Visser, L., Jamieson, A. T., Lechner, and Kaighn, 524 mary Tumor (TPDMT-4) and Related Autono and Hay, J. Specific Viral Antigens in Rat Cells MarneÂ«, L. J., and Tuttle. M. A. Comparison of mous Lines, 3361 Transformed by Herpes Simplex Virus Type 2 the Mutagenicities of Malondialdehyde and the Mattammal, M. B. See Zenser, Mattammal, Arm and in Rat Tumors Induced by Inoculation of Side Products Formed during Its Chemical Syn brecht, and Davis. 2839; Zenser, Mattammal, Transformed Cells, 2074 thesis. 276 and Davis. 114 Madanat, F. F. See Wang, Madanat, Kimball, Marogil, M. See Anderson, Bonomi. Marogil, Hen- Matus, R. E. See Gordon, Moroff, Hurvitz, Matus, Gleiser, Ali, Kaufman, and van Eys, 1022 drickson, and Economou, 4127 MacEwen, Good, and Day, 3627 Madelrnont, J-C. See GodenÃ¨che, Madelmont, MÃ¡rquez, E. D., Backenstose, J. M., and Chap Maybaum, J., Ullman, B., Mandel, H. G., Day, J. Moreau, Montoloy, and Plagne, 3351 man, J. L. Depletion of Total Hemolytic Comple L, and Sadee, W. Regulation of RNA- and DNA- Madison, L. 0. See Evans, Madison, and Eidlen, ment in Sera from Hamsters Bearing Herpes Directed Actions of 5-Fluoropyrimidines in 395 Simplex Type 2-induced Tumors. 713 Mouse T-Lymphoma (S-49) Cells, 4209 Maekawa, T. See Miura, Nogiwa, Kurashige, and Marsden, H. B. See Kumar, Kumar, Marsden, Mayer, R. J. See Siber, Mayer, and Levin. 3430 Maekawa, 4813 Lynch, and Earnshaw, 2010 Maynard, J. R. See Crutchley, Conanan, and May- MagÃn,R. L. See Weinstein, Magin, Cysyk, and Marsh, J. C. See Bennett and Marsh, 80; nard. 849 Zaharko, 1388 Schwartz, Dunigan, Marsh, and Handschu- McCarthy, D. See Babiarz-Tracy. McCarthy, Si Magrath, I. T. See Bode. Magrath. Bleyer, Po- macher, 1885 mon, Burlingham, and Fondy, 3274 plack, and Glaubiger, 2184 Marsh, P. S. See Goodman, Hoekstra, and Marsh, McClatchy, J. K. See Brunda, Mathews, Fergu Magun, B. E. See Haddox, Magun, and Russell. 2336 son, McClatchy, and Minden, 3211 604 Martel, N. See Yamasaki, Saint-Vincent, and Mar McCormick, D. L., Burns, F. J., and Albert, R. E. MÃ¤her, V. M. See Aust, Falahee, MÃ¤her, and tel, 3780 Inhibition of Rat Mammary Carcinogenesis by McCormick. 4070 Marti, J. R. See Loo, Friedman, Moore, Valdivieso, Short Dietary Exposure to Retinyl Acetate, 1140 Mahoney, K. H., Morse, S. S., and Moraban, P. Marti, and Stewart. 86 McCormick, J. J. See Aust. Falahee. MÃ¤her,and S. Macrophage Functions in Beige (ChÃ©diak- Martin, D. S. See Stolti, Sawyer, Nayak, Spiegel- McCormick, 4070 Higashi Syndrome) Mice, 3934 man, and Martin. 2730 McCredie, K. See Ho, Carter, Brown, Hester. Mahony, J. See Baumal. Marks, Mahony, and Martin, G. R. See Murray, Liotta, Rennard, and McCredie, Benjamin. Freireich, and Bodey, Bose. 1630 Martin, 347 2441 Mak, W. W-N., Sattler, C. A., and Pitot, H. C. Martin, T. J. See Findlay, deLuise, Michelangeli, McGuire, W. L. See Edwards, Murthy, and Mc- Accumulation of Actin Microfilaments in Adult Ellison, and Martin, 1311; Findlay. Michelan Guire, 1722; Everson, Lippman, Thompson, Rat Hepatocytes Cultured on Collagen Gel/Ny geli. Eisman, Frampton, Moseley, Maclntyre, McGuire. Wittliff. De Sombre. Jensen. Singhak- lon Mesh, 4552 Whitehead, and Martin. 4764 owinta. Brooks, and Neifeld, 991 Makita, A. See Gasa, Makita, Kameya, Kodama. Martinez, A. M. See Strniste, Martinez. Martinez, Mclntire, K. R. Tumor Markers for Radioimmuno- Araki, Yoneyama. Hirama, and Hashimoto, and Brake, 245 detection of Cancer. 3083 â€¢.See a/so Rockoff, 3804 Martinez, E. See Strniste. Martinez. Martinez, and Goodenough. and Mclntire, 3054* Makuch, R. See Von Hoff, Casper, Bradley, Trent, Brake, 245 Mclntyre, B. W. See Glenney. Kaulfus, Mclntyre, Hodach, Reichert, Makuch, and Altman, 3591 Marton, L. J. See Fulton, Levin, Lubich, Wilson, and Walborg, 2853 Malaisse, W. J., Sener, A., Herchuelz, A., Car- and Marton, 3293; Seidenfeld and Marton. McKeown, J. See Spratt, Adcock. Muskovin. plnelli, A. R., Poloczek, P., Winand, J., and 1961 Sherrill, and McKeown, 256 Castagna, M. Insulinotropic Effect of the Tumor Mashiba, H. See Yagawa. Kaku, Manabe, Yasu- McKhann, C. F. See Yu. Lannin, Tsui-Collins, and Promoter ^-O-Tetradecanoylphorbol-IS- moto. Mashiba, Iribe, Yamagata, Takenaka, and McKhann, 2756 acetate in Rat Pancreatic Islets. 3827 Nomura. 4791 McKnight, B. See Shellabarger, McKnight. Stone, Malaveille, C. See Sabadle, Malaveille. Camus. Mastrangelo, M. J. See Herlyn. Clark, Mastran- and Holtzman, 1808 and Bartsch, 119; Zajdela, Croisy, Barbin, Ma gelo. Guerry, Elder, LaRossa, Hamilton, Bondi, McLachlan, J. A., Newbold, R. R., and Bullock, laveille, Tomatis, and Bartsch, 352 Tuthill, Steplewski, and Koprowski, 3602 B. C. Long-Term Effects on the Female Mouse Malt, R. A. See Williamson. Bauer, Terpstra, Ross, Mastro, A. M., and Pepin, K. G. Suppression of Genital Tract Associated with Prenatal Expo and Malt. 538 Lectin-stimulated DMA Synthesis in Bovine Lym sure to Diethylstilbestrol, 3988 Manabe, H. See Yagawa, Kaku, Manabe, Yasu- phocytes by the Tumor Promoter 12-O-Tetra- McLellan, W. L. See Raz. McLellan, Hart, Bucana. moto, Mashiba, Iribe, Yamagata, Takenaka. and decanoylphorbol-13-acetate. 3307 Hoyer, Sela, Dragsten, and Fidler. 1645 Nomura. 4791 Mathe. G. See Mori. Jasmin, Hayat, Macdonald, McLoughlin, G. A. See Wang, McLoughlin, Richie, Mandel, H. G. See Maybaum. Ullman, Mandel, and Mathe. 4282 and Mannick, 288 Day, and Sadee, 4209 Mathews, H. L. See Brunda, Mathews, Ferguson, McMahon, J. B., and lype, P. T. Specific Inhibition Mandybur, T. I. See Kalter, Mandybur. Ormsby, McClatchy. and Minden, 3211 ; Minden and Ma- of Proliferation of Nonmalignant Rat Hepatic and Warkany, 3973 thews, 3214 Cells by a Factor from Rat Liver, 1249 Mannl, A. See Arafah, Cullino. Marini, and Pear Matsubara, S., Suzuki, M., and Ishida, N. Im McMillan, P. J., Thaete, L. G., Hooker, W. M., son, 4628 paired Induction of Type II Interferon in Tumor- and Roos, B. A. Immunohistology, Light Micros Mannick, J. A. See Steele, Wang, Richie. Wilson, bearing Mice, 873 copy, and Ultrastructural Morphology of Trans- Ervin. Yankee, FallÃ³n, and Mannick, 2377; Matsubara, S., Suzuki, M., Nakamura, M., Edo, plantable Rat Medullary Thyroid Carcinomas,

DECEMBER1980 4855 Author Index to Volume 40

1419 Mihailovich, N. See Vesselinovitch, Itze. Mihailov- on Treatment with 6-Mercaptopurine Riboside McNamura. P. See Cook and McNamura. 1329 ich, and Rao, 1538 of Mice Bearing L1210 Leukemia Cells. 4813 Meade-Cobun, K. S. See Ruddon. Anderson, and Mihich. E. See Bogyo and Mihich, 650; Tomazic, Miyamoto, K., and Terasaki. T. Mechanism of the Meade-Cobun, 4519; Ruddon. Bryan, Meade- Ehrke. and Mihich, 2748 Linkage between the Electrophoretic Mobility Cobun, and Pollack, 4007 Mikles-Robertson, F., Dave, C., and Porter, C. and Oxygen Uptake of Ascites Tumor Cells, Medina, D. See Asch, Medina. Kretzer, Connolly, W. Apparent Autophagocytosis of Mitochondria 4751 and Brinkley, 2383 in L1210 Leukemia Cells Treated in Vitro with Mizuhira, V. See Fukuda. Shindo. Shimizu. Arak- Medina, D., Butel, J. S., Socher, S. H., and Miller, 4,4'-Diacetyl-diphenylurea-bis(guanylhydra- awa, and Mizuhira, 133 F. L. Mammary Tumorigenesis in 7,12-Di- zone), 1054 Mizuno, D. See Kurisu, Yamazaki, and Mizuno, methylbenzanthracene-treated C57BL x DBA/ Milgrom, E. See PichÃ³n, Pallud, Brunei, and Mil- 3798 2f F, Mice. 368 grom, 3357 Mizuno, Y. See Matsuzawa, Mizuno, Yamamoto, Medina, D., and Oborn, C. J. Growth of Preneo- Milholland. R. J. See Ip, Milholland, and Rosen, Hori, and Suzuki, 3361 plastic Mammary Epithelial Cells in Serum-free 2188 Mizuochi, T. See Yoshima, Mizuochi, Ishii, and Medium, 3982 Miller, B. E., Miller, F. R., Leith, J., and Heppner, Kobata, 4276 Medina, D., Oborn, C. J., and Asch, B. B. Distinc G. H. Growth Interaction in Vivo between Tumor Mizushima, Y. See Minami, Kasai, Mizushima, tion between Preneoplastic and Neoplastic Subpopulations Derived from a Single Mouse Takeichi, Hosokawa and Kobayashi, 2129 Mammary Cell Populations in Vitro by Cytocha- Mammary Tumor. 3977 Moachon, G. See Asselin, Melancon, Moachon, lasin B-induced Multinucleation, 329 Miller, E. C. See Dahl, Miller, and Miller. 1194; and BÃ©langer,1612 Meerman, J. H. N., van Doom, A. B. D., and Tarpley. Miller, and Miller, 2493 Moan, J., Waksvik, H., and Christensen, T. DNA Mulder, G. J. Inhibition of Sulfate Conjugation Miller, F. L. See Medina, Butel, Socher, and Miller. Single-Strand Breaks and Sister Chromatid Ex of N-Hydroxy-2-acetylaminofluorene in Isolated 368 changes Induced by Treatment with Hemato- Perfused Rat Liver and in the Rat in Vivo by Miller, F. R. See Miller, Miller. Leith. and Heppner. porphyrin and Light or by X-Rays in Human Pentachlorophenol and Low Sulfate, 3772 3977 NHIK 3025 Cells, 2915 Mehta, J. R., Przybylski, M., and Ludlum, D. B. Miller, J. A. See Dahl, Miller, and Miller, 1194; Moccio, D. M. See Sirotnak and Moccio, 1230 Alkylation of Guanosine and Deoxyguanosine Tarpley, Miller, and Miller, 2493 Mochizuki, M., Irving, C. C., Anjo. T., Wakabay- by Phosphoramide Mustard, 4183 Mills, G. See Slaga. Gleason. Mills, Ewald, Fu, ashi. Y., Suzuki, E., and Okada, M. Synthesis Mehta, R. G.. Cerny, W. L., and Moon, R. C. Lee. and Harvey, 1981 and Mutagenicity of 4-

4856 CANCER RESEARCH VOL. 40 Author Index to Volume 40

Moore, R. E., Goldsworthy, T. L., and Pitot, H. C. Ethyl-N-nitrosourea, 887 Nakamura, S. See Koji, Ishii, Munehisa, Kusu Turnover of 3'-Polyadenylate-containing RNA in MÃ¼ller,R. E., Sheard, B. E., Traish, A., and moto, Nakamura. Tamenishi, HarÃ¡, Kobayashi, Livers from Aged, Partially Hepatectomized, Wotiz, H. H. Effect of Chemotherapeutic Agents Tsukada, Nishi, and Hirai, 3013' Neonatal, and Morris 5123C Hepatoma-bearing on the Formation of Estrogen-Receptor Com Nakanishi, Y. See Isohashi. Tsukanaka, Terada, Rats, 1449 plex in Human Breast Tumor Cytosol, 2941, Nakanishi, Tani. and Sakamoto, 877 Morahan, P. S. See Mahoney, Morse, and Mora- Letter fo (he Editor Nakata, Y., Ochi, T., Kurisaki, E., Okano, H., han, 3934 Muller-Eberhard, U. See Johnson. Levitt. Muller- Mamada, H., Amitani, K., Tanabe, S., Ono, K., More, N. See Rahman, Kessler, More, Sikic, Row- Eberhard, and Thorgeirsson, 4456 and Sakamoto, Y. Identification of Type A and den, Woolley, and Schein, 1532 Munehisa, T. See Koji, Ishii, Munehisa, Kusumoto, Type C Virus Particles in BF Murine Osteosar- Moreau, M-F. See GodenÃ¨che, Macininoli!. Mo Nakamura, Tamenishi, HarÃ¡, Kobayashi, Tsu- coma, 127 reau, Montoloy, and Plagne, 3351 kada, Nishi, and Hirai, 3013* Namer, M., Lalanne, C., and Baulieu, E-E. In Mori, K. J., Jasmin, C., Hayat, M., Macdonald, J. Murgo, A. J., Fried, J., Burchenal, D., Vale, K. crease of Progesterone Receptor by Tamoxifen S., and Mathe, G. In Vivo Study of Acute Me- L., Strife, A., Woodcock, T., Young, C. W., and as a Hormonal Challenge Test in Breast Cancer, matotoxicity of Three Nitrosoureas, Chlorozo- Clarkson, B. D. Effects of Thymidine and Thy- 1750, Communication tocin, (Chloro-2-ethyl)-1 -ribofuranosyl-3-nitro- midine plus 5-Fluorouracil on the Growth Kinet Narayan, K. S. See Boreiko, Mondai, Narayan, sourea, and (Chloro-2-ethyl)-1-ribopyranosyl-3 ics of a Human Lymphoid Cell Line, 1543 and Heidelberger, 4709 nitrosourea, 4282 Murphey, M. M. See Somers and Murphey, 4410 Narita, N. See Kitamura, Uchida, Hayata, Yama- Mori, M. See Enomoto, Dempo, Mori, and Onoe, Murphy, G. See Kennedy, Murphy, and Little, guchi, Okamoto, Narita, and Matsumoto. 4781 1769; Kaneko. Dempo, Kaku, Yokoyama, Sa- 1915 Nasrallah, A. G., Gallagher, M. T., Priest, E. L., toh, Mori, and Onoe. 1658 Murphy, G. P. See Kuriyama, Wang, Papsidero, and Trentin, J. J. Comparative Effects of Differ Morimoto, K., and Wolff, S. Increase of Sister Killian, Shimano, Valenzuela, Nishiura, Murphy, ent Strains of Corynebacterium parvum on Nat Chromatid Exchanges and Perturbations of Cell and Chu, 4658; Lee, Murphy, and Chu, 1245; ural Cell-mediated Cytotoxicity, 4159 Division Kinetics in Human Lymphocytes by Papsidero, Wang, Valenzuela, Murphy, and Nathans, A. H. See Golomb, Nathans, and Daw- Benzene Metabolites, 1189 Chu, 2428; Papsidero, Wojcieszyn, Horoszew- son, 1907 Morimoto, M., Green, D., Rahman, A., Goldin, icz, Leong, Murphy, and Chu, 3032* Natoli, C. See Ranelletti, lacobelli, Carmignani, A., and Schein, P. S. Comparative Pharmacol Murphy, M. See Evans, Hilf, Murphy, and Bos- Sica, Natoli, and Tonali, 2020 ogy of Pentamethylmelamine and Hexamethyl- mann, 3103 Nayak, R. See Stolti, Sawyer, Nayak, Spiegelman, melamine in Mice, 2762 Murphy, S. G. See Hersh, Patt, Murphy, Dicke, and Martin. 2730 Morizane, T., Kumagai, N., Tsuchimoto, K., Wa- Zander, Adegbite, and Goldman, 3134 Nayar, K. T., Levy, J. A., O'Neill, B., and Kouri, tanabe, T., and Tsuchiya, M. Specific Immu- Murray, A. W. See Fitzgerald and Murray, 2935 R. E. Xenotropic Virus Expression and Suscep nodiagnosis of Hepatoma by Tube Leukocyte Murray, E. See Von Hoff, Pollard. KÃ¼hn,Murray, tibility to 3-Methylcholanthrene-induced Can Adherence Inhibition Assay and a Modified and Coliman, 1516 cer, 4364 Method of Repeated Tube Leukocyte Adher Murray, J. C., Liotta, L., Rennard, S. I., and Neal, G. E., and Cabrai, J. R. P. Effect of Partial ence Inhibition Assay, 2928 Martin, G. R. Adhesion Characteristics of Mu Hepatectomy on Response of Rat Liver to Afla- Moroff, S. See Gordon, Moroff, Hurvitz, Matus, rine Metastatic and Nonmetastatic Tumor Cells toxin B,, 4739 MacEwen, Good, and Day, 3627 in Vitro, 347 Nedrud, J. G. See Vesterinen, Nedrud, Collier, Morris, H. P. See Bauer, BÃ¼chsel,Morris, and Murray, T. G. See Chawla, Shlaer, Lawson, Mur Walton, and Pagano, 512 Reutter, 2026; Bize, Oberley. and Morris, 3686; ray, Schmidt, Shoji, Nixon. Richmond, and Rud- Neefe, J. R. See Csako, Binder. Kales, and Neefe, Jackson, Lui, Boritzki, Morris, and Weber, man, 3915 3218 1286; Kizaki, Morris, and Weber, 3339; Kizaki, Murthy, S. R. See Edwards, Murthy, and McGuire. Neifeld, J. P. See Everson, Lippman, Thompson, Williams, Morris, and Weber, 3921; Raju, Mor 1722 McGuire, Wittliff, De Sombre, Jensen. Singhak- ris, and Busch, 1623 Muskovin, M. See Spratt, Adcock, Muskovin, owinta, Brooks, and Neifeld, 991 Morris, L. E. See Tagnon, Blot, Stroube, Day, Sherrill. and McKeown, 256 Nelson, J. A. See Weigent and Nelson. 4381 Morris, Peace, and Fraumeni, 3875 Muszynski, M. See Birnbaum, Muszynski, and Nelson, M. O. See Kim, DeLand, Nelson, Bennett, Morrison, B. H., Ill See Kalberer and Morrison, Roos, 4192 Simmons, Alpert, and Gcldenberg, 3008' 2617 Myers, C. E. See Ozols, Willson, Weltz. Grotzin- Nelson-Rees, W. A., VandrÃ©,D. D., and Mont Morrison, G. See Rogers, Lenhart, and Morrison, ger, Myers, and Young, 4109; Speyer, Collins, gomery, R. Potential for Inappropriate Thera 2802 Dedrick, Brennan, Buckpitt, Londer, DeVita, peutic Application of Drug as a Result of the Morrissey, L. W., Sidky, Y. A., and Auerbach, R. and Myers, 567 Use of Cell Substrates of Uncertain Derivation. Regional Differences in the Growth of Tumor Myers-Robfogel, M. W., and Spataro, A. C. 1-/3- Correspondence re: D. D. VandrÃ©,V. L. Shep Cells Injected Intraperitoneally Into Syngeneic D-Arabinofuranosylcytosine Nucleotide Inhibi herd, and R. Montgomery. Effects of Macro- Adult Mice, 2197 tion of Sialic Acid Metabolism in WI-38 Cells, momycin on the Ultrastructure and Biological Morse, S. S. See Mahoney, Morse, and Morahan, 1940 Properties of Cultured Mammalian Cells. Cancer 3934 Res., 39: 4091 -4097, 1979, page 1761, Letter Morton, K. C., Beland, F. A., Evans, F. E., Fuller- N to the Editor ton, N. F., and Kadlubar, F. F. Metabolic Acti Nesnow, S. See Gold, Nesnow, Moore. Garland, vation of N-Hydroxy-N.W-diacetylbenzidine by NÃ¡dasdi, L. See BÃ¶rzsÃ¶nyi,TÃ¶rÃ¶k,Pinter, Surjan, Curtis, Howard, Graham, and Eisenstadt, 4482 Hepatic Sulfotransferase, 751 NÃ¡dasdi, and Roller, 2925 Nettesheim, P. See Topping and Nettesheim, Moseley, J. M. See Findlay, Michelangeli, Eisman, Nadler, L. M., Stashenko, P., Hardy, R., Kaplan, 4352 Frampton, Moseley, Maclntyre, Whitehead, and W. D., Button, L. N., Kufe, D. W., Antman, K. Neumann, G. See Lotan, Neumann, and Lotan, Martin, 4764 H., and Schlossman. S. F. Serotherapy of a 1097 Mosselmans, R. See Wanson, Bernaert, Penasse, Patient with a Monoclonal Antibody Directed Neville, A. M. See Sloane, Ormerod. and Neville, Mosselmans, and Bannasch, 459 against a Human Lymphoma-associated Anti 3079' Mossman, B. T., Ezerman, E. B., Adler, K. B., gen. 3147 Newberne, P. M., and Connor, M. Sequential and Craighead, J. E. Isolation and Spontaneous Nagai, S. See Izumi, Nagai, and Suginoshita, 444 Exposure to Aflatoxin Bi and Diethylnitrosamine Transformation of Cloned Lines of Hamster Tra Naganuma, K. See Tsuruo, Naganuma, lida, and in Rats: Vascular and Stomach Tissue. Addi chÃ©alEpithelial Cells, 4403 Tsukagoshi, 4758 tional Target Organs. 4037 Muchmore, A. V. See Kleinerman, Zwelling, and Nagase, M. See Tanooka, Hoshino, Tanaka, and Newbold, R. R. See McLachlan, Newbold, and Muchmore, 3099 Nagase. 2547 Bullock, 3988 Muel, B. See Perin-Roussel, Croisy-Delcey, Mis- Nagatsu, T. See Fujita, Ito, Inoue, Yamamoto, Newman, R. A., Kimberly, P. J., Stewart, J. A., pelter, Saguem, Chalvet, Ekert, Fouquet, Jac- Takeuchi, Shamoto. and Nagatsu, 2543 and Kelley, J. Assessment of Bleomycin Lung quignon, Lhoste, Muel, and Zajdela, 1742 Nagayama, J. See Lee and Nagayama, 3297 Toxicity Using Angiotensin-converting Enzyme Mueller, G. C. See Verma, Slaga, Wertz, Mueller, Nagel, D. See Langenbach, Gingell, Kuszynski, in Pulmonary Lavage, 3621 and Boutwell, 2367; Wertz and Mueller, 776 Walker, Nagel, and Pour, 3463; Pour, Cingoli, Newton, D. L., Henderson, W. R., and Sporn, M. Mueller, S. N. See Baird, Chemerys, Grinspan, Langenbach, Nagel, Grandjean, Lawson, and B. Structure-Activity Relationships of Retinoids Mueller, and Levine, 1781 Salmasi, 3585 in Hamster TrachÃ©alOrgan Culture, 3413 Mukhtar, H. See Lee, Suzuki, Mukhtar, and Bend, Nagle, D. S., and Blumberg, P. M. Activity of Niijima. T. See Kakizoe, Komatsu. Niijima, Ka- 2486 Phorbol Ester Tumor Promoters on Enucleated wachi, and Sugimura, 2006 Mulder, G. J. See Meerman, van Doom, and Swiss 3T3 Cells, 1066 Nishi, S. See Koji, Ishii. Munehisa. Kusumoto, Mulder, 3772 Nakajima, T. See Watanabe, Shimosato, Kuroki, Nakamura. Tamenishi, HarÃ¡, Kobayashi, Tsu MÃ¼ller,R., and Rajewksy, M. F. Immunological Sato, and Nakajima, 2588 kada, Nishi, and Hirai, 3013' Quantification by High-Affinity Antibodies of O6- Nakamura, M. See Matsubara, Suzuki, Naka Nishida, K. See Yamanaka, Kato, Nishida, Shim- Ethyldeoxyguanosine in DNA Exposed to W- mura, Edo, and Ishida, 2534 izu, Fukushima, and Ota, 2051

DECEMBER 1980 4857 Author Index to Volume 40

Nishikawa, H. See Yoshimoto, Inoue, lizuka, Ni- Ohno, S. See Spira, Babonits, Wiener, Ohno, Wir- Order, S. E., Klein, J. L., Ettinger, D., Alderson, shikawa. Sakatani, Ogura, Hirao, and Yama- schubski. Haran-Ghera, and Klein, 2609 P., Siegelman, S., and Leichner, P. Use of Isotopie Immunoglobulin in Therapy, 3001 â€¢ mura, 4301 Ohnuki, Y., Mameli, M. M., Babcock, M. S., Lech- Nishiura, T. See Kunyama, Wang, Papsidero, Kil- ner, J. F., and Kaighn, M. E. Chromosomal Ormerod, M. G. See Sloane, Ormerod. and Ne lian, Shimano, Valenzuela. Nishiura, Murphy, Analysis of Human Prostatic Adenocarcinoma ville, 3079' and Chu, 4658 Cell Lines, 524 Orrnsby, I. See Kalter, Mandybur, Ormsby, and Nissen, N. I. See Vindolov. Hansen. Christensen, Ohtsuru, M., Ishii, Y., Takai, S-L, Higashi, H., and Warkany, 3973 Spang-Thomsen, Hirsch, Hansen, and Nissen, Kosaki, G. Sister Chromatid Exchanges in Lym Oruambo, F. I. See Banerjee, Van Duuren, and 4295 phocytes of Cancer Patients Receiving Mito- Oruambo, 2170 Nixon, D. W. See Chawla, Shlaer, Lawson, Mur mycin C Treatment, 477 Osborne, C. K., Hamilton, B., Titus, G., and ray, Schmidt, Shoji, Nixon, Richmond, and Rud- Oh-Uti, K., Inoue, S., and Minato, S. Purification Livingston, R. B. Epidermal Growth Factor man. 3915 of an Anemia-inducing Factor from Human Pla Stimulation of Human Breast Cancer Cells in Nobin, A. See HafstrÃ¶m, Nobin, Persson, and centa and Its Application to Diagnosis of Malig Culture, 2361 Sundqvist, 481 nant Neoplasms, 1686 Ossowski, L., and Reich, E. Experimental Model Noble, R. L. Development of Androgen-stimulated Oikawa, A. See Tohda, Horaguchi, Takahashi, for Quantitative Study of Metastasis, 2300; Loss Transplants of Nb Rat Carcinoma of the Dorsal Oikawa, and Matsushima, 4775 of Malignancy during Serial Passage of Human Prostate and Their Response to Sex Hormones Okada, G., Watanabe, Y., and Tsukada, K. Carcinoma in Culture and Discordance between and Tamoxifen, 3551; Production of Nb Rat Changes in Patterns of S-Adenosylmethionine Malignancy and Transformation Parameters. Carcinoma of the Dorsal Prostate and Response Synthetases in Fetal and Postnatal Rat Liver, 2310 of Estrogen-dependent Transplants to Sex Hor 2895 Ota, K. See Yamanaka, Kato, Nishida, Shimizu, mones and Tamoxifen, 3547. See a/so Gout. Okada, K., Yamada, S., Kawashima, Y., Kitade, Fukushima, and Ota, 2051 Beer, and Noble, 2433 F., Okajima, K., and Fujimoto, M. Cell Injury by Otter, G. M. See Schmid, Otter, and Stock, 830 Noble, R. L., Beer, C. T., and Gout, P. W. Evi Antineoplastic Agents and Influence of Coen- Ove, P. See Short, Klein, Kibert, and Ove, 2417 dence in Vivo and in Vitro of a Role for the zyme Qi0 on Cellular Potassium Activity and Overgaard, J., Suit, H. D., and Walker, A. M. Pituitary in the Growth of Malignant Lymphomas Potential Difference across the Membrane in Multifractionated Hyperthermia Treatment of in Nb Rats. 2437 Rat Liver Cells. 1663 Malignant and Normal Tissue in Vivo, 2045 Noda, K-i. See Griffin and Noda. 2768 Okada, M. See Mochizuki, Irving, Anjo, Wakabay- Owen, K., Gomolka, D., and Droller, M. J. Pro Nogiwa, E. See Miura. Nogiwa. Kurashige. and ashi. Suzuki, and Okada, 162 duction of Prostaglandin E2 by Tumor Cells in Maekawa, 4813 Okajima, K. See Okada, Yamada, Kawashima, Vitro, 3167 Nomura, T. Timing of Chemically Induced Neopla Kitade, Okajima, and Fujimoto, 1663 Oyasu, R. See Rowland, Henneberry, Oyasu, and sia in Mice Revealed by the Antineoplastic Ac Okamoto, K. See Tokita, Tanaka, Sekimoto, Grayhack, 4524 tion of Caffeine, 1332 Ueno, Okamoto, and Fujimura, 4287 Ozols, R. F., Willson, J. K. V., Grotzinger, K. R., Nomura, Y. See Yagawa, Kaku, Manabe, Yasu- Okamoto, S. See Kitamura, Uchida, Hayata, Ya- and Young, R. C. Cloning of Human Ovarian moto, Mashiba, Iribe, Yamagata, Takenaka, and maguchi, Okamoto. Narita, and Matsumoto. Cancer Cells in Soft Agar from Malignant Effu Nomura, 4791 4781 sions and Peritoneal Washings, 2743 Norvell, S. T. See Ghose, Norvell, Aquino, Belit- Okano, H. See Nakata, Ochi, Kurisaki. Okano, Ozols, R. F., Willson, J. K. V., Weltz, M. D., sky, Tai, Guclu, and Blair, 3018' Hamada, Amitani, Tanabe, Ono, and Sakamoto, Grotzinger, K. R., Myers, C. E., and Young, R. Noshiro, M. See Kawajiri, Yonekawa, Harada, No- 127 C. Inhibition of Human Ovarian Cancer Colony shir o. Omura, and Tagashira. 1652 Okuda, J. See Koizumi, Tamiya-Koizumi, Fuji!, Formation by Adriamycin and Its Major Metab Noterman, J. A. See Gerner. Holmes, Stickney, Okuda, and Kojima, 909 olites, 4109 Noterman, and Fuller, 432 Olah, E., Lui, M. S., Tzeng, D. Y., and Weber, G. Nove, J. See Weichselbaum, Nove, and Little, 920 Phase and Cell Cycle Specificity of Pyrazofurin Nowak, N. J. See Pavelic, Slocum, Rustum, Action, 2869 Creaven, Nowak, Karakousis, Takita, and Mit- Old, L. J. See DuBois, Appella, Law, DeLeo, and Pachter, J. A. See DuVernay, Pachter, and telman, 4151 Old, 4204 Crooke, 387 Nowinski, R. C. See Tam, Green, and Nowinski, Oliver, R. P. See Sutherland, Cimino, Delihas, Pacifici, M., and Holtzer, H. 12-O-Tetradecanoyl- 3850 Shih, and Oliver, 1934 phorbol-13-acetate-induced Changes in Sul- Oliver, R. T. D. See Kuhns, Oliver, Watkins, and fated Proteoglycan Synthesis in Cultured Chon- Greenwell, 268 droblasts, 2461 Olsen, G. A., Glasgow, L. A., and Dethlefsen, L. Padula, E. See Giovarelli, Padula, Ugazio, Forni, A. Alteration of Murine Mammary Tumor Metas and Cavallo, 3745 Oberley, L. W. See Bize, Oberley. and Morris, tasis and Growth by Cytomegalovirus Infection, Pagano, J. S. See Vesterinen, Nedrud, Collier, 3686 853 Walton, and Pagano, 512 Oborn, C. J. See Medina and Oborn, 3982: Med Olsnes, S. See Tveit, Fodstad, Brogger. and Paigen, B. See Gurtoo, Vaught, Marinone. Paigen, ina, Oborn, and Asch, 329 Olsnes, 949 Gessner, and Bolanowska, 1305 O'Brien, T. G., and Saladik, D. Differences in the Olson, J. W., and Russell, D. H. Prolonged Orni- Paik, C. H. See Eckelman, Paik, and Reba, 3036* Metabolism of [3H]12-O-Tetradecanoylphorbol- thine Decarboxylase Induction in Regenerating, Palan, P. R., and Romney, S. L. Cellular Binding 13-acetate and [3H]Phorbol-12,13-Didecanoate Carcinogen-treated Liver, 4373 Proteins for Vitamin A in Human Carcinomas by Cells in Culture, 4433 Olstad, R., Gaudernack, G., Kaplan, G., and Sel- and in Normal Tissues, 4221 Ochi, T. See Nakata, Ochi, Kurisaki, Okano, Ha- jelid, R. T- and B-Cell-independent Activation of Pallante, S. L., Fenselau, C., Mennel, R. G., mada, Amitani, Tanabe, Ono, and Sakamoto, Syngeneic Macrophages by Murine Sarcoma Brundrett, R. B., Appier, M., Rosenshein, N. 127 Cells, 2054 B., and Colvin, M. Quantitation by Gas Chro Oesch, F. See Glatt, Kaltenbach, and Oesch, Omura, T. See Kawajiri, Yonekawa, Harada, No matography-Chemical lonization-Mass Spec- 2552 shiro, Omura, and Tagashira, 1652 trometry of Phenylalanine Mustard in Plasma of O'Neill, B. See Nayar, Levy, O'Neill, and Kouri, Oesterle, D. See Demi and Cesterie, 490 Patients, 2268 Ogawa, K.. Sott, D. B., and Farber, E. Phenotypic 4364 Palleroni, A. V. See Trown, Palleroni, Bohos- Diversity as an Early Property of Putative Pre- O'Neill, J. P. See Johnson, Hoeschele, Rahn. lawec, Richelo, Halpern, Gizzi, Geiger, Lewin- O'Neill, and Hsie, 1463 neoplastic Hepatocyte Populations in Liver Car- ski, Machlin, Jetten, and Jetten, 212 cinogenesis, 725 Ono, K. See Nakata, Ochi, Kurisaki, Okano, Ha Pallud, C. See PichÃ³n, Pallud, Brunei, and Mil- Ogihara, K. See Kataoka, Ogihara, and Sakurai, mada, Amitani, Tanabe, Ono, and Sakamoto, grom, 3357 3839 127 Pamukcu, A. M., YalÃ§iner,S., Hatcher, J. F., and Ogino, S. See Yoshida, Kiyohara, Fukui, Atsumi, Ono, T. See Fiorine, Ono, Cutler, and Getz, 519 Bryan, G. T. Quercetin. a Rat Intestinal and Ogino, Inaba, Tsukagoshi, and Sakurai. 3810 Onoe, T. See Enomoto, Dempo, Mori, and OnoÃ©, Bladder Carcinogen Present in Bracken Fern Ogura, T. See Yoshimoto, Inoue, lizuka, Nishi 1769; Kaneko, Dempo, Kaku, Yokoyama, Sa- (Pteridium aquilinum ), 3468 kawa, Sakatani, Ogura, Hirao, and Yamamura, toh, Mori, and OnoÃ©,1658 Papathanasopoulos, N. See Kirkwood, Ensmin- 4301 Ookhtens, M. See Kannan, Ookhtens, and Baker, ger, Rosowsky, Papathanasopoulos, and Frei, Oh-hashi, F. See Kataoka, Oh-hashi, Sakurai, and 2447 107 Gomi, 3832 Ootsu, K., Kozai, Y., Takeuchi, M., Ikeyama, S., Papsidero, L. D. See Kuriyama, Wang, Papsidero, Ohki, K. See Barrett, Sheela, Ohki, and Kakun- Igarashi, K., Tsukamoto, K., Sugino, Y., Tash- Killian, Shimano, Valenzuela, Nishiura, Murphy, aga, 1438 iro, T., Tsukagoshi, S., and Sakurai, Y. Effects and Chu, 4658 Ohi, V. S. See Smith, Ohi, and Litwack, 1787 of New Antimitotic Antibiotics, Ansamitocins, on Papsidero, L. D., Wang, M. C., Valenzuela, L. A., Ohmori, T. See Hecht, Chen, Ohmori, and Hoff the Growth of Murine Tumors in Vivo and on the Murphy, G. P., and Chu, T. M. A Prostate mann. 298 Assembly of Microtubules in Vitro, 1707 Antigen in Sera of Prostatic Cancer Patients,

4858 CANCER RESEARCH VOL. 40 Author Index to Volume 40

2428 and Solvolysis in Vitro. 782 terone Receptors to Prognosis in Early Breast Papsidero, L. D., Wojcieszyn, J. W., Horoszew- Pedersen, N. See Lutz, Pedersen, Higgins, Cancer, 3357 icz, J. S., Leong, S. S., Murphy, G. P., and HÃ¼bscher,Troy, and Theilen, 3642 Piddington, S. K. See Fox, Tripp, Piddington, and Chu, T. M. Isolation of Prostatic Acid Phospha- Pegg, A. E. See Montesano, BrÃ©sil,Planche-Mar Tattersall, 3383 tase-binding Immunoglobulin G from Human tel, Margison, and Pegg, 452 Pietropaolo, C. See Colletta, Di Fiore, Ferrentino, Sera and Its Potential for Use as a Tumor-local Pelus, L. M., Broxmeyer, H. E., Clarkson, B. D., Pietropaolo, Turco, and Vecchio, 3369 izing Reagent, 3032* and Moore, M. A. S. Abnormal Responsiveness Pihl, A. See Fodstad and Pini, 3735 Parham, J. C., and Templeton, M. A. Compara of Granulocyte-Macrophage-committed Colony- Pinedo, H. M. See Breed, Zimmerman, Dormans, tive Reactivities of Esters of Oncogenic and forming Cells from Patients with Chronic Mye- and Pinedo, 2033; Buesa-Perez, Leyva, and Nononcogenic Purine N-Oxides and Evidence loid Leukemia to Inhibition by Prostaglandin E, Pinedo, 139 of the Oxidation-Reduction Reactivity of Aro 2512 Pinter, A. See BÃ¶rzsÃ¶nyi.TÃ¶rÃ¶k,Pinter, Surjan, matic Nitrenium Ions, 1475 Penasse, W. See Wanson, Bernaert, Penasse, NÃ¡dasdi, and Roller, 2925 Park, C. H., Amare, M., Savin, M. A., and Hoogs- Mosselmans, and Bannasch, 459 Pitelka, D. R., Hamamoto, S. T., and Taggart, B. traten, B. Growth Suppression of Human Leu- Pepin, K. G. See Mastro and Pepin, 3307 N. Basal Lamina and Tissue Recognition in Ma kemic Cells in Vitro by L-Ascorbic Acid, 1062 Peraino, C., Staffeldt, E. F., Haugen, D. A., Lom lignant Mammary Tumors, 1600; Epithelial Cell Parker, R. See Greenberg, Caruana, Holcomb, bard, L. S., Stevens, F. J., and Fry, R. J. M. Junctions in Primary and Metastatic Mammary Greenberg, Parker, Louis, and White, 439 Effects of Varying the Dietary Concentration of Tumors of Mice, 1588 Parshad, R., Sanford, K. K., Jones, G. M., Tar- PhÃ©nobarbital on Its Enhancement of 2-Acetyl- Pitot, H. C. See Mak, Sattler, and Pitot. 4552; one, R. E., Hoffman, H. A., and Grier, A. H. aminofluorene-induced Hepatic Tumorigenesis, Moore, Goldsworthy, and Pitot, 1449; Sirica, Susceptibility to Fluorescent Light-induced 3268 Hwang, Sattler, and Pitot, 3259 Chromatid Breaks Associated with DMA Repair Perchellet, J-P., and Boutwell, R. K. Enhance Pitot, H. C., Goldsworthy, T., Campbell, H. A., Deficiency and Malignant Transformation in Cul ment by 3-lsobutyl-1-methylxanthine and Chol and Poland, A. Quantitative Evaluation of the ture, 4415 era Toxin of 12-O-Tetradecanoylphorbol-13- Promotion by 2,3,7,8-Tetrachlorodibenzo-p- Partick, E. J. See Russell and Partick, 3719 acetate-stimulated Cyclic Nucleotide Levels and dioxin of Hepatocarcinogenesis from Diethylni- Pasqualini, J. R. See Gulino and Pasqualini, 3821 Ornithine Decarboxylase Activity in Isolated Ep trosamine, 3616 Patii, S. R., Corder, M. P., Jochimsen, P. R., and idermal Cells, 2653 Pitts, A. M. See Green, Pretlow, Tucker, Bradley, Dick, F. R. Bone Marrow Chromosome Abnor Perin-Roussel, O., Croisy-Delcey, M., Mispelter, Cook, Pitts, and Pretlow, 1791 malities in Breast Cancer Patients following Ad J., Saguem, S., Chalvet, O., Ekert, B., Fou- Piver, S. M. See Wake, Hreshchyshyn, Piver, Mat- juvant Chemotherapy, 4076 quet, J., Jacquignon, P., Lhoste, J-M., Muel, sui, and Sandberg. 4512 Patt, Y. Z. See Hersh, Patt, Murphy, Dicke, Zan B., and Zajdela, F. E. Metabolic Activation of Plagne. R. See GodenÃ¨che, Madelmont, Moreau. der, Adegbite, and Goldman, 3134 Dibenzo(a,e)fluoranthene, a Nonalternant Car Montoloy, and Plagne, 3351 Patton, J. A. See Rollo and Patton, 3050' cinogenic Polycyclic Hydrocarbon, in Liver Ho- Planche-Martel, G. See Montesano, BrÃ©sil, Paul, D. See Rupniak and Paul, 293 mogenates, 1742 Planche-Martel, Margison, and Pegg, 452 Pauley, R. J., and Socher, S. H. Hormonal Influ Perk, K. Correspondence re: J. K. Ball and J. A. Platica, M., Bojko, C., and Hollander, V. P. Trans ences on the Expression of Casein Messenger McCarter. Biological Characterization of a Leu- plantation of Primary Plasma Cell Tumor without RNA during Mouse Mammary Tumorigenesis, kemogenic Virus Isolated from the CFW Mouse. 2.6,10,14-Tetramethylpentadecane (Pristane) 362 Cancer Res., 39. 3080-3088, 1979, page Treatment of the Hosts, 579 Pauli, B. U., Anderson, S. N., Memoli, V. A., and 1765. Letter to the Editor Platica, M., Bojko, C., Steiner, G., and Hollander, Kuettner, K. E. Development of an in Vitro and Perkins, E. H. See Yuhas and Perkins, 3403 V. P. Effect of Subcutaneously Administered in Vivo Epithelial Tumor Model for the Study of Perkins, E. H., and Cacheiro, L. H. Immuno- 2,6,10.14-Tetramethylpentadecane on Plas- Invasion, 4571 depression, a Noncontributor to Radiation-in macytoma Growth. 2229 Paulson, D. F. See Shrivastav, Bonar, Stone, and duced Leukemogenesis of the RFM Mouse, 357 Pleshkewych, A., Kramer, D. L., Kelly, E., and Paulson. 4438; Shrivastav, Stone. Paulson, and Perlmann, P. See Lando, Blomberg, Berzins, and Porter, C. W. Independence of Drug Action on Bonar, 4443 Perlmann, 1691 Mitochondria and Polyamines in L1210 Leuke Pauly, J. E. See Scheving. Burns, Pauly, and Persson, B. See HafstrÃ¶m, Nobin, Persson, and mia Cells Treated with Methylglyoxal- Halberg, 1511 Sundqvist, 481 Bis(Guanylhydrazone). 4533 Pavelic, Z. P. See Dobrossy, Pavelic, Vaughan, Petering, D. H. See Krishnamurti, Saryan, and Plummer, J. L. See Smith, Plummer, Ball, and Porter, and Bernacki, 3281; Kinahan, Pavelic, Petering, 4092 Bend, 101 Leonard, Bloch, and Grindey, 598 Peterson, A. R. DNA Synthesis, Mutagenesis, Plunkett, W., Chubb, S., Alexander, L., and Pavelic, Z. P., Dave, S., Bialkowski, S., Priore, DMA Damage, and Cytotoxicity in Cultured Montgomery, J. A. Comparison of the Toxicity R. L., and Greco, W. R. Antitumor Activity of Mammalian Cells Treated with Alkylating and Metabolism of 9-/?-o-Arabinofuranosyl-2- Corynebacterium parvum and Retinyl Palmitate Agents, 682 fluoroadenine and 9-/3-D-Arabinofuranosylade- Used in Combination on the Lewis Lung Carci Peterson, R. D. A., Varakis, J. N., and Cheshire, nine in Human Lymphoblastoid Cells, 2349 noma, 4617 L. B. New Experimental Model of Meningeal Plunkett, W., Hug, V., Keating, M. J., and Chubb, Pavelic, Z. P., Slocum. H. K., Rustum, Y. M., Leukemia, 3130 S. QuantitÃ¤ten of 1-/8-p-Arabinofuranosylcyto- Creaven, P. J., Karakousis, C., and Takita, H. Petkas, A. See Kann, Blumenstein, Petkas, and sine S'-Triphosphate in the Leukemic Cells from Colony Growth in Soft Agar of Human Mela Schott, 771; Kann, Schott, and Petkas, 50 Bone Marrow and Peripheral Blood of Patients noma, Sarcoma, and Lung Carcinoma Cells Dis Petrakis, N. L., Maack, C. A., Lee, R. E., and Receiving 1-/i-o-Arabinofuranosylcytosine aggregated by Mechanical and Enzymatic Meth Lyon, M. Mutagenic Activity in Nipple Aspirates Therapy, 588 ods, 2160 of Human Breast Fluid, 188 Pochron, S. See Petralia, Soprano. Pochron, Dar- Pavelic, Z. P., Slocum, H. K., Rustum, Y. M., Petralia, S., Soprano, K. J., Pochron, S., Darzyn- zynkiewicz. TrÃ¡ganos, and Baserga, 3177 Creaven, P. J., Nowak, N. J., Karakousis, C., kiewicz, Z., TrÃ¡ganos, F., and Baserga, R. Podhajcer, O. L., Friedlander, M., and Graziani, Takita, H., and Mittelman, A. Growth of Cell Increase in Cellular RNA in Cells Infected with Y. Effect of Liposome-encapsulated Quercetin Colonies in Soft Agar from Biopsies of Different DNA Oncogenic Viruses, 3177 on DNA Synthesis, LÃ¡clate Production, and Human Solid Tumors, 4151 Petti!, W. A., DeLand, F. H., Bennett, S. J., and Cyclic Adenosine 3':5'-Monophosphate Level in Pavkov, K. L. See Swenberg, Kerns, Mitchell, Goldenberg, D. M. Radiolabeling of Affinity-pu Ehrlich Ascites Tumor Cells, 1344 Gralla, and Pavkov, 3398 rified Goat Anti-Carcinoembryonic Antigen Im Poirier, M. C., Santella, R., Weinstein, l. B., Grun- Pawlowski, A., Haberman, H. F., and Menon, I. munoglobulin G with Technetium-99m, 3043' berger, D., and Yuspa, S. H. QuantitÃ¤ten of A. Skin Melanoma Induced by 7,12-Dimethyl- Pewnim, T., Adams, J. B., and Ho, K. P. A Rela Benzo(a)pyrene-Deoxyguanosine Adducts by benzanthracene in Albino Guinea Pigs and Its tionship between Estrogen Sulfurylation and Es Radioimmunoassay, 412 Similarities to Skin Melanoma of Humans, 3652 trogen and Progesterone Receptor Status in Poland, A. See Pitot, Goldsworthy, Campbell, and Payette, R., Biehl, J., Toyama, Y., Holtzer, S., Human Mammary Carcinoma, 1360. Communi Poland. 3616 and Holtzer, H. Effects of 12-O-Tetradecanoyl- cation Politzer, I. R. See Politzer, Politzer, and Seybold, phorbol-13-acetate on the Differentiation of Philips, F. S. See Warrell, Chou, Gordon. Tan, 2943 Avian Melanocytes, 2465 Roberts, Sternberg. Philips, and Young. 4546; Politzer, P., Politzer, l. R., and Seybold, P. G. Peace, B. B. See Tagnon, Blot, Stroube, Day, Woodcock, Chou, Tan, Sternberg, Philips, Third Annual Interdisciplinary Cancer Research Morris, Peace, and Fraumeni, 3875 Young, and Burchenal, 4243 Workshop, 2943, Meeting Report Pearson, O. H. See Arafah, Cullino. Manni, and Phillips, T. L. See Begg, Fu, Kane, and Phillips, Pollack, V. A. See Ruddon, Bryan, Meade-Cobun. Pearson, 4628 145 and Pollack, 4007 Peck, C. See Roberts, Hilliard, and Peck, 4225 Piacibello, W. See Aglietta. Piacibello, and Ga- Pollard, E. See Von Hoff. Pollard, KÃ¼hn,Murray, Peck, E. B. See Peck and Peck, 782 vosto, 2507 and Coltman, 1516 Peck, R. M., and Peck, E. B. Relationships be PichÃ³n, M-F., Pallud, C., Brunet, M., and Mil- Poloczek, P. See Malaisse. Sener. Herchuelz, tween Carcinogenesis in Vivo and Alkylation grom, E. Relationship of Presence of Proges Carpinelli, Poloczek, Winand, and Castagna,

DECEMBER1980 4859 Author Index to Volume 40

3827 Pruitt, B. See Rose, Pruitt, Stauber, Ertiirk, and Rao, K. V. K. See Blackburn, Andrews, Rao, and Ponlzer, C. H. See lype and Pontzer, 4663 Bryan, 235 Sorof, 4688 Pool, T. B. See Cameron, Smith, Pool, and Prusoff, W. H. See Kan-Mitchell, Mitchell, Lin, and Rao, K. V. N. See Vesselinovitch, Itze, Mihailovich, Sparks. 1493 Prusoff, 3491 and Rao, 1538 Poole, A. R. See Recklies, Tiltman, Stoker, and Przepiorka, D., Mokyr, M. B., and Dray, S. Effect Rao, M. S. See Reddy, Rao, Warren, Qureshi, and Poole. 550 of Polyethylene Glycol 6000 on the Generation Christensen, 3443; Scarpelli, Rao, Subbarao, Poplack, D. G. See Bode. Magrath, Bleyer, Po- of Antitumor Cytotoxicity in MOPC-315 Tumor- Beversluis. Gurka. and Hollenberg. 67 plack, and Glaubiger, 2184; Jackson, Castle, Bearer Spleen Cells Cultured in the Presence or RÃ¢per,S. M. See Herzfeld and RÃ¢per,744 Poplack, and Bender. 722 Absence of Inactivated Stimulator Tumor Cells, Rapp, H. J. See Ashley, Zbar, Hunter, Rapp, and Portengen, H. See Teulings, van Gilse, Henkel- 4565 Sugimoto, 4197; Yarkoni and Rapp, 975; Zbar, man. Portengen, and Alexieva-Figusch, 2557 Przybylski, M. See Mehta, Przybylski, and Lud- Canti, Rapp, Ashley, Sukumar, and Bast, 1036 Porter, C. W. See Mikles-Robertson. Dave, and lum, 4183 Rawls, W. E. See Gilman, Docherty, Clarke, and Porter, 1054; Pleshkewych. Kramer. Kelly, and Rawls. 4640; Rosenthal, Tompkins, and Rawls, Porter, 4533 4744 Porter, C. W., Dworaczyk, D., Gams, B., and Raymond, J. See Karasaki, Suh, Salas, and Ray Weiser, M. M. Polyamines and Biosynthetic En mond, 1318 Qureshi, S. A. See Reddy, Rao, Warren, Qureshi, zymes in the Rat Intestinal Mucosa and the Raz, A. See Fidler, Raz, Fogler, Kirsh, Bugelski, and Christensen. 3443 Influence of Methylglyoxal-bis(guanylhydra- and Poste. 4460 zone), 2330 Raz, A., McLellan, W. L., Hart, I. R., Bucane, C. Porter, N. See Dobrossy. Pavelic. Vaughan, Por D., Hoyer, L. C., Sela, B-A., Dragsten, P., and ter, and Bernacki, 3281 Fidler, I. J. Cell Surface Properties of B16 Mel Porzio, N. R. See Bart. Porzio, Kopf, Vilcek, Rabson, A. S. See Rosen, Calvert, Weintraub, anoma Variants with Differing Metastatic Poten Cheng, and Farcet, 614 Tseng, and Rabson, 4325 tial, 1645 Poste, G. See Fidler, Raz, Fogler, Kirsh, Bugelski, Radomski, J. L., Deichmann, W. B., Altman, N. Razek, A., Valeriote, F., and Vietti, T. Effect of and Poste, 4460 H., and Radomski, T. Failure of Pure 1-Naph- Dose Fractionation of Daunorubicin on Survival Poste, G., Doll, Jâ€žHart, I. R., and Fidler, I. J. In thylamine to Induce Bladder Tumors in Dogs, of Leukemic Cells, 2835 Vitro Selection of Murine B16 Melanoma Var 3537 Razzouk, C., Mercier, M., and Roberfroid, M. iants with Enhanced Tissue-invasive Properties, Radomski, T. See Radomski, Deichmann, Altman, Induction, Activation, and Inhibition of Hamster 1636 and Radomski. 3537 and Rat Liver Microsomal Arylamide and Aryl- Potsaid, M. S. See Castronovo, Potsaid. and Ko- Rae-Venter, B., and Reid, L. M. Growth of Human amine N-Hydroxylase, 3540 piwoda, 3473 Breast Carcinomas in Nude Mice and Subse Reba, R. C. See Eckelman, Paik. and Reba, Poulakos, L. See Dow, Bell, Poulakos, and Frid- quent Establishment in Tissue Culture, 95 3036' land, 1405 Rahman, A. See Morimoto. Green. Rahman, Gol Recklies, A. D., Tiltman, K. J., Stoker, T. A. M., Pour, P. See Langenbach, Gingell, Kuszynski, din, and Schein, 2762 and Poole, A. R. Secretion of Proteinases from Walker, Nagel, and Pour, 3463 Rahman, A., Kessler, A., More, N., Sikic, B., Malignant and Nonmalignant Human Breast Tis Pour, P., Gingell, R., Langenbach, R., Nagel, D., Rowden, G., Woolley, P., and Schein, P. S. sue, 550 Grandjean, C., Lawson, T., and Salmasi, S. Liposomal Protection of Adriamycin-induced Reddy, J. K. See Warren, Simmon, and Reddy, Carcinogenicity of N-Nitrosomethyl(2-oxopro- Cardiotoxicity in Mice, 1532 36 pyDamine in Syrian Hamsters, 3585 Rahn, R. O. See Johnson, Hoescnele, Rahn, Reddy, J. K., Rao, M. S., Warren, J. R., Qureshi, O'Neill, and Hsie, 1463 Prashad, N., Rosenberg, R., Baskin, F., Spark- S. A., and Christensen, E. I. Differentiation and man, D., Ulrich, C., and Wischmeyer, B. Cyclic Raient, R. F., Cohen, B. I., Fazzini, E. P., Sarwal, DNA Synthesis in Pancreatic Acinar Carcinoma Adenosine 3':5'-Monophosphate-binding Pro A. N., and Takahashi, M. Protective Effect of of Rat, 3443 tein, a Biochemical Marker of Neuroblastoma Plant Sterols against Chemically Induced Colon Redwood, W. R., and Colvin, M. Transport of Differentiation, 2884 Tumors in Rats, 403 Melphalan by Sensitive and Resistant L1210 Pratt, C. B. See Rivera, Evans, Dahl, Yee, and Rainbow, A. J. Reduced Capacity to Repair Irra Cells, 1144 Pratt. 4250 diated Adenovirus in Fibroblasts from Xero- Reeder, T. A. See HiÃ±e,Bradwell, Reeder, Droic, Presek, P., Glossmann, H., Eigenbrodt, E., derma Pigmentosum HÃ©tÃ©rozygotes,3945 and Dykes, 2993* Schoner, W., RÃ¼bsamen,H., Friis, R. R., and Rajewsky, M. F. See MÃ¼llerand Rajewsky, 887 Reich, E. See Ossowski and Reich, 2300. 2310 Bauer, H. Similarities between a Phosphopro- Raju, K. S., Morris, H. P., and Busch, H. Purifi Reichert, C. M. See Bradley. Reichert, Brennan, tein (pp60"c)-associated Protein Kinase of Rous cation and Characterization of Cytosol Protein and Von Hoff, 3694; Von Hoff, Casper, Bradley, Sarcoma Virus and a Cyclic Adenosine 3':5'- 45/7.8 Present in Rapidly Growing Hepatomas. Trent, Hodach, Reichert. Makuch, and Altman, Monophosphate-independent Protein Kinase 1623 3591 That Phosphorylates Pyruvate Kinase Type M2, Ralph, P. See Broxmeyer, Ralph, Gilbertson, and Reid, L. M. See Rae-Venter and Reid, 95 1733 Margolis. 3928 Reiners, J. J., Jr., Davis, F. M., and Busch, H. Pressman, D. The Development and Use of Radio- Ramonas, L. M. See Erickson. Ramonas, Za- Identification of Polysomes Synthesizing Novi- labeled Antitumor Antibodies, 2960* harko, and Kohn, 4216 koff Hepatoma Nucleolar Antigens, 1367 Prestayko, A. W. See Mong. Huang, Prestayko. Ramonas, L. M., Erickson, L. C., Ringsdorf, H., Relyea, N. M. See Wainfan, Brody, Relyea, and and Crooke, 3313. 3318 and Zaharko, D. S. Effect of Dose, Schedule, Balis. 620 Pretlow, T. G., II See Green, Pretlow, Tucker. and Route of Administration on the in Vivo Tox- Rennard, S. I. See Murray, Liotta. Rennard, and Bradley, Cook, Pitts, and Pretlow, 1791 ; Hem- icity and Antitumor Activity of Two Activated Martin, 347 street, Enoch, and Pretlow. 1043 Sulfhydryl Derivatives of Cyclophosphamide, Reuber, M. D. See Lijinsky and Reuber, 19; Lijin- Pretlow, T. P. See Green. Pretlow. Tucker, Brad 3704 sky, Saavedra, Reuber, and Blackwell. 3325 ley, Cook, Pitts, and Pretlow. 1791 Ramselaar, C. G., Ruitenberg, E. J., and Krui- Reutter, W. G. See Bauer, BÃ¼chsel,Morris, and Priest, E. L. See Nasrallah. Gallagher. Priest, and zinga, W. Regression of Induced Keratoacan- Reutter, 2026 Trentin, 4159 thomas in Anagen (Hair Growth Phase) Skin Revoltella, R. See Fioritoni, Bertolini, Torlontano, Primus, F. J. See Goldenberg. Kim, DeLand, Ben Grafts in Mice, 1668 and Revoltella, 866 nett, and Primus. 2984'; van Nagell, Kim, Cas Randerath, K. See Lu and Randerath, 2701 Reznik-SchÃ¼ller,H. M., Lijinsky, W., and Hague, per, Primus, Bennett, DeLand, and Goldenberg, Randolph, J. K. See Gewirtz, Randolph, and Gold B. F., Jr. Electron Microscopic Autoradiography 502 man. 1852; Gewirtz, White, Randolph, and of the Pancreas in the Hamster Treated with Primus, F. J., Bennett, S. J., Kim, E. E., DeLand, Goldman, 573 Tritiated W-Nitroso-2,6-dimethylmorpholine, F. H., Zahn, M. C., and Goldenberg, D. M. Ranelletti, F. 0., lacobelli, S., Carmignani, M., 2245 Circulating Immune Complexes in Cancer Pa Sica, G., Natoli, C., and Tonali, P. Glucocorti- Rice, L. See Urano and Rice, 959 tients Receiving Goat Radiolocalizing Antibod coid Receptors and in Vitro Corticosensitivity in Richards, B. See Gerweck, Jennings, and Rich ies to Carcinoembryonic Antigen, 497 Human Thymoma, 2020 ards, 4019 Primus, F. J., and Goldenberg, D. M. Immunolog- Rankin, P. W., Jacobson, M. K., Mitchell, V. R., Rlchelo, B. N. See Trown, Palleroni, Bohoslawec, ical Considerations in the Use of Goat Antibod and Busbee, D. L. Reduction of Nicotinamide nichelo, Halpern, Gizzi, Geiger, Lewinski, ies to Carcinoembryonic Antigen for the Ra- Adenine Dinucleotide Levels by Ultimate Carcin Machlin. Jetten, and Jetten. 212 dioimmunodetection of Cancer, 2979' ogens in Human Lymphocytes, 1803 Richie, J. P. See Steele, Wang, Richie, Wilson, Priore, R. L. See Pavelic, Dave, Bialkowski, Priore, Ranney, D. F. See Widder, Senyei, and Ranney, Ervin, Yankee, FallÃ³n, and Mannick, 2377; and Greco, 4617 3512 Wang. McLoughlin, Richie, and Mannick, 288 Pris, J. See Kessous, Colombies. Pris, and Clem Rao, K. N., Takahashi, S., and Shinozuka, H. Richmond, A. See Chawla, Lawson, Richmond, ent, 1354 Acinar Cell Carcinoma of the Rat Pancreas and Rudman, 4187; Chawla, Shlaer, Lawson, Prough, R. A. See Wiebkin and Prough, 3524 Grown in Cell Culture and in Nude Mice, 592 Murray. Schmidt, Shoji, Nixon, Richmond, and

4860 CANCER RESEARCH VOL. 40 Author Index to Volume 40

Rudman, 3915 berg, and Cannon, 325 and Genetic Signature Analysis of Cultured Hu Rieber, M., and Rieber, M. S. Effect of Malignant Rosenshein, N. B. See Pallante. Fenselau. Men- man Colon Adenocarcinoma Cell Lines LS180 Transformation and Arginine Limitation on Fi- nel, Brundrett, Appier, Rosenshein, and Colvin, and LS174T, 1443 bronectin and Other Cell Surface Macromole- 2268 Ryan, D. E. See Wood, Chang, Levin, Ryan. cules of Liver Epithelial Cultures, 2562 Rosenthal, K. L., Tompkins, W. A. F., and Rawls, Thomas, Croisy-Delcey, Utah. Yagi, Jerina. and Rieber, M. S. See Rieber and Rieber. 2562 W. E. Factors Affecting the Expression of Car- Conney. 2876; Wood, Levin, Chang. Huang, Ringsdorf, H. See Hirano. Ringsdorf, and Za- cinoembryonic Antigen at the Surface of Cul Ryan, Thomas, Lehr, Kumar, Koreeda, Akagi, harko, 2263; Ramonas, Erickson, Ringsdorf, tured Human Colon Carcinoma Cells. 4744 Utah, Dansette, Yagi, Jerina, and Conney, 642 and Zaharko, 3704 Rosowsky, A. See Kirkwood, Ensminger, Ro- Ryan, V. See Kreis, Baker, Ryan, and Bertasso. Rltenour, E. R. See Looney, Ritenour, and Hop sowsky, Papathanasopoulos, and Frei, 107 634 kins, 2179 Ross, C. P. See Thompson, Ross. Strada, Hersh, Rivenson, A. See Hecht, Rivenson, and Hoffmann, and Lavis, 1955 S 1396 Ross, J. S. See Williamson, Bauer, Terpstra, Ross, Rivera, G., Evans, W. E., Dahl, G. V., Yee, G. C., and Malt, 538 Saat, Y. A. See Krishnaraj, Saat, and Kemp, 2808 and Pratt, C. B. Phase I Clinical and Phar- Ross, L. A. See Egorin, Clawson, Cohen, Ross, Saavedra, J. E. See Lijinsky. Saavedra, Reuber, macokinetic Study of 4'-(9-Acridinylamino>- and Bachur, 4669; Egorin, Clawson, Ross, and and Blackwell. 3325 methanesulfon-m-anisidide in Children with Bachur, 1928 Sabadle, N., Malaveille, C., Camus, A-M., and Cancer, 4250 Rosselin, G. See Laburthe, Roussel, Chevalier, Bartsch, H. Comparison of the Hydroxylation of Robbins, J. H. See Doniger, Barrett, and Robbins, Boissard, Dupont, Zweibaum, and Rosselin, Benzo(a)pyrene with the Metabolism of Vinyl 2736 2529 Chloride, N-Nitrosomorpholine, and W-Nitroso- Roberfroid, M. See Razzouk, Mercier, and Rob- Rossi, M., Cantrell, J. S., Farber, A. J., Dyott, T., N'-Methylpiperazine to Mutagens by Human erfroid, 3540 Carrell, H. L., and Glusker, J. P. Molecular and Rat Liver Microsomal Fractions. 119 Roberts, D., Milliard, S., and Peck, C. Sedimen Structures of 5,6- and 7,8-Benzoflavones, In Sadee, W. See Au and Sadee, 2814; Maybaum. tation of DNA from L1210 Cells after Treatment hibitors of Aryl Hydrocarbon Hydroxylase, 2774 Ullman, Mandel, Day, and Sadee, 4209 with 4'-Demethylepipodophyllotoxin-9-(4,6-0- Roti Roti, J. L. See Wotring and Roti Roti, 1458 Saguem. S. See Perin-Roussel, Croisy-Delcey, 2-Thenylidene-/3-D-Glucopyranoside) or 1-/J-D- Roussel, M. See Laburthe, Rousset, Chevalier, Mispelter, Saguem, Chalvet, Ekert, Fouquet, Arabinofuranosylcytosine or Both Drugs, 4225 Boissard, Dupont, Zweibaum, and Rosselin, Jacquignon, Lhoste, Muel, and Zajdela, 1742 Roberts, J. See Warrell, Chou, Gordon, Tan, Rob 2529 Saint-Vincent, L. See Yamasaki, Saint-Vincent, erts, Sternberg, Philips, and Young, 4546 Rowden, G. See Rahman, Kessler. More, Sikic, and Martel, 3780 Roblin, R., and Young, P. L. Dexamethasone Reg Rowden, Woolley, and Schein. 1532 Saito, D., Sawamura, M., Umezawa, K., Kanai, ulation of Plasminogen Activator in Embryonic Rowland, R. G., Henneberry, M. 0., Oyasu, R., Y., Furihata, C., Matsushima, T., and Sugi- and Tumor-derived Human Cells, 2706 and Grayhack, J. T. Effects of Urine and Con mura, T. Inhibition of Experimental Blood-borne Rockoff, S. D., Goodenough, D. J., and Mclntire, tinued Exposure to Carcinogen on Progression Lung Metastasis by Protease Inhibitors, 2539 K. R. Theoretical Limitations in the Immunodi- of Early Neoplastic Urinary Bladder Lesions, Sakagami, Y. See Takenaga. Hozumi, and Saka- agnostic Imaging of Cancer with Computed To 4524 gami, 914 mography and Nuclear Scanning, 3054' Rowley, J. D. Second International Workshop on Sakaguchi, K. See Watanuki and Sakaguchi, Rockwell, S. See Kennedy, Rockwell, and Sarto- Chromosomes in Leukemia, 4826, Meeting Re 2574 relli, 2356 port Sakamoto, Y. See Isohashi, Tsukanaka, Terada, Rogers, A. E., Lenhart, G., and Morrison, G. RÃ¼bsamen,H. See Presek, Glossmann, Eigen- Nakanishi, Tani, and Sakamoto, 877; Nakata, Influence of Dietary Lipotrope and Lipid Content brodt, Schoner, RÃ¼bsamen. Friis, and Bauer, Ochi, Kurisaki, Okano, Hamada, Amitani, Tan- on Aflatoxin Bi, N-2-Fluorenylacetamide, and 1733 abe, Ono, and Sakamoto, 127 1,2-Dimethylhydrazine Carcinogenesis in Rats, Rudali, G. See Drosdowsky, Edery, Guggiari, Sakatani, M. See Yoshimoto, Inoue, lizuka, Nishi- 2802 Montes-Rendon, Rudali, and Vives, 1674 kawa, Sakatani, Ogura, Hirao, and Yamamura, Rolfe, P. B. See Laishes and Rolfe, 4133 Ruddon. R. W. See Waalkes, Abeloff. Woo, Ettin- 4301 Roller, P. See BÃ¶rzsÃ¶nyi,TÃ¶rÃ¶k,Pinter, Surjan, ger, Ruddon, and Aldenderfer, 4420 Sakurai, Y. See Kataoka. Ogihara. and Sakurai. NÃ¡dasdi, and Roller, 2925 Ruddon, R. W., Anderson, C., and Meade- 3839; Kataoka, Oh-hashi, Sakurai, and Gomi, Rollo, F. D., and Patton, J. A. Imaging Techniques Cobun, K. S. Stimulation of Synthesis and Se 3832; Ootsu, Kozai, Takeuchi, Ikeyama. Igar- for the Radioimmunodetection of Cancer, cretion of Chorionic Gonadotropin Subunits by ashi, Tsukamoto, Sugino. Tashiro, Tsukagoshi, 3050' Eutopic and Ectopie Hormone-Producing Hu and Sakurai, 1707; Yoshida, Kiyohara, Fukui, Romic-Stojkovic, R., and Gamulin, S. Relation man Cell Lines, 4519 Atsumi, Ogino, Inaba, Tsukagoshi, and Sakurai, ship of Cytoplasmic and Nuclear Estrogen Re Ruddon, R. W., Bryan, A. H., Meade-Cobun, K. 3810 Saladik, D. See O'Brien and Saladik, 4433 ceptors and Progesterone Receptors in Human S., and Pollack, V. A. Production of Human Breast Cancer, 4821 Chorionic Gonadotropin and Its Subunits by Hu Salas, M. See Karasaki, Suh, Salas, and Ray Romney, S. L. See Palan and Romney, 4221 man Tumors Growing in Nude Mice, 4007 mond, 1318 Roos, B. A. See Birnbaum, Muszynski, and Roos, Rudman, D. See Chawla, Lawson, Richmond, and Salmasi, S. See Pour, Gingell. Langenbach, Na 4192; McMillan, Thaete, Hooker, and Roos. Rudman, 4187; Chawla, Shlaer, Lawson, Mur gel. Grandjean. Lawson, and Salmasi, 3585 1419 ray, Schmidt, Shoji, Nixon. Richmond, and Rud San, R. H. C. See Freeman and San, 3155 Rorke, E. A., and Katzenellenbogen, B. S. Com man, 3915 Sandberg, A. A. See Abe and Sandberg, 1292; parative Effects of Estrogen and Antiestrogens Ruitenberg, E. J. See Ramselaar, Ruitenberg, and Wake, Hreshchyshyn. Piver, Matsui, and Sand- on Enzyme Activities in R3230AC Rat Mammary Kruizinga, 1668 berg, 4512 Tumors and Uteri of Tumor-bearing Animals, Rupniak, H. T., and Paul, D. Selective Killing of Sandford, K. K. See Parshad, Sanford, Jones, 3158 Transformed Cells by Exploitation of Their De Tarone, Hoffman, and Grier, 4415 Rose, D. P., and Davis, T. E. Effects of Adjuvant fective Cell Cycle Control by Polyamines, 293 Santella, R. See Poirier, Santella. Weinstein, Chemohormonal Therapy on the Ovarian and Russell, D. H. See Haddox, Magun, and Russell, Grunberger, and Yuspa, 412 Adrenal Function of Breast Cancer Patients. 604; Olson and Russell, 4373 Santen, R. J., Collette, J., and Franchimont, P. 4043 Russell, E. K. See Gazdar, Carney, Russell, Sims, Partial Purification of Carcinoembryonic-Reac- Rose, D. P., Pruitt, B., Stauber, P., Erturk. E., Baylin, Bunn, Guccion, and Minna, 3502 tive Antigen from Breast Neoplasms Using Lee- and Bryan, G. T. Influence of Dosage Schedule Russell, G. R., and Partick, E. J. Effects of Vari tin and Antibody Affinity Chromatography, 1181 on the Biological Characteristics of W-Nitroso- ations in Nucleoside Pool Sizes on Comparisons Sarma, D. S. R. See Solt, Cayama, Sarma, and methylurea-induced Rat Mammary Tumors, 235 of the Incorporation of [3HJThymidine into Iso Farber, 1112 Rosen, F. See Ip, Milholland, and Rosen, 2188 lated Rat Liver Cells, 3719 Sarrif, A. M. See Brattain, Strobel-Stevens, Fine. Rosen, S. W., Calvert. I., Weintraub, B. D., Russo, I. H. See Russo and Russo, 2677 Webb, and Sarrif, 2142; Woodman, Sarrif, and Tseng, J. S., and Rabson, A. S. Stimulation by Russo, J., and Russo, I. H. Influence of Differen Heidelberger, 507 Dibutyryl Cyclic Adenosine 3':5'-Monophos- tiation and Cell Kinetics on the Susceptibility of Sartorelli, A. C. See Kennedy, Rockwell, and Sar- phate of Ectopie Production of the Free ÃŸSub- the Rat Mammary Gland to Carcinogenesis, torelli, 2356 unit of Chorionic Gonadotropin by a Human 2677 Sarwal, A. N. See Raicht. Cohen, Fazzini, Sarwal, Brain Tumor Cell Line, 4325, Communication Rustum, Y. M. See Danhauser and Rustum, 1274; and Takahashi, 403 Rosenberg, K. D. See Check, Hunter, Rosenberg, Pavelic, Slocum, Rustum, Creaven, Karakousis, Saryan, L. A. See Krishnamurti, Saryan, and Pe and Herbst, 4612 and Takita, 2160; Pavelic, Slocum, Rustum, tering. 4092 Rosenberg, R. See Prashad, Rosenberg, Baskin, Creaven, Nowak, Karakousis, Takita, and Mit- Sasak, W., De Luca, L. M., Dion, L. D., and Sparkman, Ulrich, and Wischmeyer, 2884 telman, 4151 SMverman-Jones. C. S. Effect of Retinole Acid Rosenberg, S. A. See Catapano, Brown, and Ro Rutzky, L. P., Kaye, C. I., Siciliano, M. J., Chao, on Cell Surface Glycopeptides of Cultured senberg, 979: Stern. Wilczek, Thorpe. Rosen M., and Kahan, B. D. Longitudinal Karyotype Spontaneously Transformed Mouse Fibroblasts

DECEMBER 1980 4861 Author Index to Volume 40

(BALB/c 3T12-3 Cells), 1944 Schweisguth, 0. See LaBrosse, Com-Nougue, Shih, A. G. See Sutherland, Cimino, Delihas, Shih, Sasaki, K., and Takahashi, M. Preservation of Zucker, Comoy, Bohuon, Lemerle, and and Oliver, 1934 Cell Cycle Characteristics in Solid Tumor in Schweisguth, 1995 Shimada, M. See Kitamura, Yokoyama, Matsuda, Vitro. 4810 Schweizer, J. See Goerttler, Loehrke, Schweizer, and Shimada, 3392 Sasaki, M. S., Tsunematsu, Y., Utsunomiya, J., and Hesse, 155 Shimano, T. See Kuriyama, Wang, Papsidero, and Utsumi, J. Site-Directed Chromosome Scott, R. E., and Dousa, T. P. Defective Cyclic Killian, Shimano, Valenzuela, Nishiura, Murphy, Rearrangements in Skin Fibroblasts from Per Adenosine 3':5'-Monophosphate-dependent and Chu, 4658 sons Carrying Genes for Hereditary Neoplasms, Phosphorylation of Plasma Membrane Proteins Shimizu, F. See Fukuda, Shindo, Shimizu, Arak- 4796 in Chemically and Virally Transformed Cells, awa, and Mizuhira, 133 Sato, Y. See Watanabe, Shimosato, Kuroki, Sato, 2860 Shimizu, K., Ushio, Y., Hayakawa, T., and Me- and Nakajima, 2588 Scudiero, D. A. Decreased DNA Repair Synthesis garni, H. Combination Chemotherapy with 1-(4- Satoh, M. See Kaneko, Dempo, Kaku, Yokoyama, and Defective Colony-forming Ability of Ataxia Amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chlo- Satoh, Mori, and OnoÃ©,1658 Telangiectasia Fibroblast Cell Strains Treated roethyl)-3-nitrosourea Hydrochloride and Bleo- Sattler, C. A. See Mak, Sattler, and Pilot, 4552 with N-Methyl-W-nitro-N-nitrosoguanidine, 984 mycin in Meningeal Carcinomatosis in Rats, Sattler, G. L. See Sirica, Hwang, Sattler, and Searle, F. See Bagshawe, Searle, Lewis, Brown, 1341 Pilot, 3259 and Keep, 3016' Shimizu, S. See Yamanaka, Kato, Nishida, Shim Savin, M. A. See Park, Amare, Savin, and Hoogs- Secrist, J. A., Ill See Iyer, Lyga, Secrist, Daub, izu, Fukushima, and Ota, 2051 traten, 1062 and Slaga, 1073 Shimkin, M. B. See Theiss, Arnold, and Shimkin, Saviolakis, G. A. See Strickland, Saviolakis, Segal, W. See Urban, Edwards, and Segal, 1501 4322; Theiss, Shimkin, Stoner, Kniazeff, and Weislow, Allen, Hellman, and Fowler, 3570 Seidenfeld, J., and Marton, L. J. Effects of OL-a- Hoppenstand, 64 Sawamura, M. See Saito, Sawamura, Umezawa, Methylornithine on Proliferation and Polyamine Shimosato, Y. See Watanabe, Shimosato, Kuroki, Kanai, Furihata, Matsushima, and Sugimura, Content of 9L Rat Brain Tumor Cells, 1961 Sato, and Nakajima, 2588 2539 Sekimoto, K. See Tokita, Tanaka, Sekimoto, Shindo, H. See Fukuda, Shindo, Shimizu, Arak- Sawyer, R. C. See Stolti, Sawyer, Nayak, Spie- Ueno, Okamoto, and Fujimura, 4287 awa, and Mizuhira, 133 gelman, and Martin, 2730 Sela, B-A. See Raz, McLellan, Hart, Bucana, Shingleton, H. M. See Lawrence, Shingleton, Saxholm, H. J. K., and Digernes, V. Progressive Hoyer, Sela, Dragsten, and Fidler, 1645 Gore, and Soong, 1558 Loss of DMA and Lowering of the Chromosomal Selikoff, I. J. See Chahinian, Beranek, Suzuki, Shinozuka, H. See Rao, Takahashi, and Shino- Mode in Chemically Transformed C3H/10T'/2 Bekesi, Wisniewski, Selikoff, and Holland, 181 zuka, 592 Cells during Development of Their Oncogenic Seljelid, R. See Olstad, Gaudernack, Kaplan, and Shinozuka, H., and Lombardi, B. Synergistic Ef Potential, 4254 Seljelid, 2054 fect of a Choline-devoid Diet and PhÃ©nobarbital Scarpelli, D. G., Rao, M. S., Subbarao, V., Bev- Selkirk, J. K. See Cohen, MacLeod, Moore, and in Promoting the Emergence of Foci of y-Gluta- ersluis, M., Gurka, D. P., and Hollenberg, P. F. Selkirk, 207 myltranspeptidase-positive Hepatocytes in the Activation of Nitrosamines to Mutagens by Post- Sener, A. See Malaisse, Sener, Herchuelz, Car- Liver of Carcinogen-treated Rats, 3846, Com- mitochondrial Fraction of Hamster Pancreas, 67 pinelli, Poloczek, Winand, and Castagna, 3827 munication Schabe!, F. M., Jr. See Brockman, Cheng, Scha- Senyei, A. E. See Widder, Senyei, and Ranney, Shirai, T. Lack of Enhancing Effect of Mucosal bel, and Montgomery, 3610 3512 Regeneration following UlcÃ©rationof the Urinary Schaeffer, W. I. See Heintz, Little, Bresnick, and Setlow, R. B. See Hill and Setlow, 1867 Bladder on W-Butyl-rV-<4-hydroxybutyl)nitros- Schaeffer, 1281 Seybold, P. G. See Politzer, Politzer, and Seybold, amine Carcinogenesis in Rats, 3709 Schein, P. S. See Ardalan, Cooney, Jayaram, 2943 Shiu, M. H., and Fortner, J. G. Intraperitoneal Carrico, Glazer, Macdonald, and Schein, 1431 ; Seymour-Munn, K. See Adams, Archibald, and Hyperthermic Treatment of Implanted Peritoneal Morimoto, Green, Rahman, Goldin, and Schein, Seymour-Munn, 3815 Cancer in Rats, 4081 2762; Rahman, Kessler, More, Sikic, Rowden, Shafer, R. H., and Chase, E. S. DNA Damage in Shlaer, S. M. See Chawla, Shlaer, Lawson, Mur Woolley, and Schein. 1532; Tew, Schein, Lind Rat 9L Cells Treated with Nitrogen Mustard and ray, Schmidt, Shoji, Nixon, Richmond, and Rud ner, Wang, and Smulson. 3697 1,3-Bis(2-chloroethyl)-1-nitrosourea Assayed man, 3915 Schenken, L. L. See Braunschweiger, Schenken, by Viscoelastometry and S, Nuclease, 3186 Shoji, M. See Chawla, Shlaer, Lawson, Murray, and Schiffer, 2257 Shah-Reddy, I. See Kessel, Shah-Roddy, Mir- Schmidt, Shoji, Nixon, Richmond, and Rudman, ScherstÃ©n,T. See Lundholm, EdstrÃ¶m,Karlberg, chandani, Khilanani, and Chou, 3576 3915 Ekman. and ScherstÃ©n, 2516; Lundholm, Ek- Shamoto, M. See Fujita, Ito, Inoue, Yamamoto, Shors, E. C., Fu, P. C., Matsumura, K., Cohen, man, Karlberg, EdstrÃ¶m, and ScherstÃ©n, 1680 Takeuchi, Shamoto, and Nagatsu, 2543 A. H., and Benfield, J. R. Sustained Release of Scheving, L. E., Burns, E. R., Pauly, J. E., and Shank, R. C. See HerrÃ³nand Shank, 3116 Benzo(a)pyrene from Silicone Polymer into the Halberg, F. Circadian Bioperiodic Response of Shapiro, S. J. See Leibson, Loken, Shapiro, and Tracheobronchial Tree of Hamsters and Dogs, Mice Bearing Advanced L1210 Leukemia to Schreiber, 56 2288 Combination Therapy with Adriamycin and Cy- Sharkey, N. A. See Bradley, Sharkey, Kohn, and Short, J., Klein, K., Kibert, L., and Ove, P. In clophosphamide, 1511 Layard, 2719 volvement of the lodothyronines in Liver and Schiffer, L. M. See Braunschweiger, Schenken, Sharma, S. See Bryant, Smith, Sharma, and Hepatoma Cell Proliferation in the Rat, 2417 and Schiffer, 2257; Braunschweiger and Schif Dodge, 4031 Showalter, S. D. See Hampar, Boyd, Derge, fer, 737 Sheard, B. E. See MÃ¼ller,Sheard, Traish, and Zweig, Eader, and Showalter, 2213 Schlom, J. See Drohan, Cardiff. Lund, and Wotiz, 2941 Shrivastav, S., Bonar, R. A., Stone, K. R., and Schlom, 2316 Shearman, C. W. See Tkeshelashvili, Shearman, Paulson, D. F. An in Vitro Assay Procedure to Schlossman, S. F. See Nadler, Stashenko, Hardy, Zakour, Koplitz, and Loeb, 2455 Test Chemotherapeutic Drugs on Cells from Hu Kaplan, Button, Kufe, Antman, and Schlossman, Sheela, S. See Barrett, Siicela, Ohki, and Kak- man Solid Tumors, 4438 3147 unaga, 1438 Shrivastav, S., Stone, K. R., Paulson, D. F., and Schmid, F. A., Otter, G. M., and Stock, C. C. Shellabarger, C. J. See Stone, Holtzman, and Bonar, R. A. Activation of Cyclophosphamide Resistance Patterns of Walker Carcinosarcoma Shellabarger, 3966 for in Vitro Testing of Cell Sensitivity, 4443 256 and Other Rodent Tumors to Cyclophos- Shellabarger, C. J., McKnight, B., Stone, J. P., Shugars, K. 0. See Bhuyan, Blowers, and Shu- phamide and L-Phenylalanine Mustard, 830 and Holtzman, S. Interaction of Dimethyl- gars, 3437 Schmidt, F. See Chawla, Shlaer, Lawson, Murray, benzanthracene and Diethylstilbestrol on Mam Shumak, K. H., Baker, M. A. Taub, R. N., Cole- Schmidt, Shoji, Nixon, Richmond, and Rudman, mary Adenocarcinoma Formation in Female ACI man, M. S., and the Toronto Leukemia Study 3915 Rats, 1808 Group Myeloblastic and Lymphoblastic Markers Schoner, W. See Presek, Glossmann, Eigenbrodt, Shepherd, V. L., Vandre, D. D., Elting, J. J., and in Acute Undifferentiated Leukemia and Chronic Schoner, RÃ¼bsamen,Friis, and Bauer, 1733 Montgomery, R. Effects of Cesalin on the Ultra- Myelogenous Leukemia in Blast Crisis, 4048 Schott, M. A. See Kann, Blumenstein, Petkas, and structure and Biological Properties of Cultured Shuster, J. See Gold and Shuster, 2973* Schott, 771 ; Kann, Schott, and Petkas, 50 Mammalian Cells, 225 Siber, G. R., Mayer, R. J., and Levin, M. J. Schreiber, H. See Leibson, Loken, Shapiro, and Sheppard, J. R. See Howard, Theologides, and Increased Gastrointestinal Absorption of Large Schreiber, 56 Sheppard, 2695 Molecules in Patients after 5-Fluorouracil Ther SchrÃ¶der, E. W., Chou, I-N., and Black, P. H. Sherblom, A. P. See Huggins, Trenbeath, Sher- apy for Metastatic Colon Carcinoma, 3430 Effects of Retinole Acid on Plasminogen Acti blom, Howard, and Carraway, 1873 Sica, G. See Ranchetti, lacobelli, Carmignani, vator and Mitogenic Responses of Cultured Sherrill, W. See Spratt, Adcock, Muskovin, Sher- Sica, Natoli, and Tonali, 2020 Mouse Cells, 3089 rill, and McKeown, 256; Spratt, Adcock, Sher Siciliano, M. J. Correspondence re: M. J. Sicili Schwartz, P. M., Dunigan, J. M., Marsh, J. C., rill, and Travathen, 253 ano, M. E. Bordelon-Riser, R. S. Freedman, and and Handschumacher, R. E. Allopurinol Modi Shieh, J-C., and Song, P-S. Photochemically In Peter O. Kohler. A Human Tropoblastic Isozyme fication of the Toxicity and Antitumor Activity of duced Binding of Aflatoxins to DNA and Its (Lactate Dehydrogenase-Z) Associated with 5-Fluorouracil, 1885 Effects on Template Activity, 689 Choriocarcinoma. Cancer Res., 40: 283-287,

4862 CANCER RESEARCH VOL. 40 Author Index to Volume 40

1980, page 3408, Letter to the Editor. See also Smith, I. E. See Bryant, Jarman, Baker, Smith, Staiano-Coico, L. See TrÃ¡ganos, Evenson, Hutzky, Kaye, Siciliano, Chao, and Kalian, 1443 and Smyth, 4734 Staiano-Coico. Darzynkiewicz. and Melamed, Siciliano, M. J., Bordelon-Riser, M. E., Freed- Smith, N. K. R. See Cameron, Smith, Pool, and 671; TrÃ¡ganos. Staiano-Coico, Darzynkiewicz, man, R. S., and Kohler, P. O. A Human Tropho- Sparks, 1493 and Melamed, 2390 blastic Isozyme (LÃ¡clate Dehydrogenase-Z) As Smith, R. See Bryant, Smith, Sharma, and Dodge, Stanley, J. R. See Yuspa. Hawley-Nelson, Ko- sociated with Choriocarcinoma, 283 4031 ehler, and Stanley, 4694 Sidky, Y. A. See Morrissey, Sidky. and Auerbach, Smuckler, E. A. See Clawson, Koplitz, Moody, Stashenko, P. See Nadler. Stashenko, Hardy, 2197 and Smuckler, 75 Kaplan, Button, Kufe, Antman. and Schlossman, Siegelman, S. See Order, Klein, Ettinger, Alder- Smulson, M. E. See Tew, Schein. Lindner, Wang, 3147 son, Siegelman, and Leichner, 3001 â€¢ and Smulson, 3697 Stauber, P. See Rose, Pruitt, Stauber, ErtÃ¼rk,and Sikic, B. See Rahman, Kessler, More, Sikic. Row- Smyth, J. F. See Bryant, Jarman, Baker, Smith, Bryan, 235 den, Woolley, and Schein. 1532 and Smyth, 4734 Steele, G., Jr. See Yang, Steele, Wang, and Man- Silverman-Jones, C. S. See Sasak, De Luca, Snead, R. M. See Long, Bruszewski, and Snead. nick, 1762; Zamcheck and Steele, 3086' Dion, and Silverman-Jones, 1944 22; Long, Suk, Snead, and Christensen, 3886 Steele, G., Jr., Wang, B. S., Richie, J., Wilson, Simmon, V. F. See Warren, Simmon, and Reddy, Snyderman, R. See Collins and Snyderman, 557 R. E., Ervin, T., Yankee, R., FallÃ³n, M., and 36 Socher, S. H. See Medina, Butel, Socher, and Mannick, J. A. In Vivo Effect and Parallel in Simmons, G. See DeLand, Kim, Simmons, and Miller, 368; Pauley and Socher, 362 Vitro Lymphocyte-mediated Tumor Cytolysis Goldenberg, 3046'; Kim, DeLand, Nelson, Ben Soloway, M. S. See Daskal, Soloway, DeFuria, after Phase I Xenogeneic Immune RNA Treat nett, Simmons, Alpert, and Goldenberg, 3008* and Crooke. 261 ment of Patients with Widespread Melanoma or Simms, E., Gazdar, A. F., Abrams, P. G., and Solt, D. B. See Ogawa, Solt, and Farber, 725 Metastatic Renal Cell Carcinoma, 2377 Minna, J. D. Growth of Human Small Cell (Oat Solt, D. B., Cayama, E., Sarma, D. S. R., and Stehlin, J. S. See Lee. Giovanella, Stehlin. and Cell) Carcinoma of the Lung in Serum-Free Farber, E. Persistence of Resistant Putative Howell, 1764 Growth Factor Supplemented Medium, 4356 Preneoplastic Hepatocytes Induced by W-Nitro- Stein, G. S. See Detke, Stein, and Stein. 967 Simon, P. See Babiarz-Tracy, McCarthy, Simon, sodiethylamine or W-Methyl-W-Nitrosourea, Stein, J. L. See Detke, Stein, and Stein. 967 Burlingham, and Fondy, 3274 1112 Steiner, G. See Platica. Bojko, Steiner, and Hol Simon, R. See DeWys, Allegra, Simon, and Lipp- Solter, D. See Bronson, Andrews, Solter, Cer- lander, 2229 man. 2423 venka. Lange, and Fraley, 2500 Steiner, M. See HarÃ¡.Steiner, and Baldini. 1212, Sims, H. L. See Gazdar, Carney, Russell, Sims, Somers, K. D., and Murphey, M. M. Multinuclea- 1217 Baylin, Bunn, Guccion, and Minna. 3502 tion in the Presence of Cytochalasin B by RNA Steplewski, Z. See Herlyn. Clark. Mastrangelo. Singh, J., Grigor, M. R., and Thompson, M. P. Tumor Virus Transformed Cells, 4410 Guerry. Elder. LaRossa, Hamilton, Bondi. Tut- Glucose Homeostasis in Rats Bearing a Trans- Song, C. W. See Kang, Song, and Levitt, 1130 hill, Steplewski, and Koprowski, 3602; Herlyn, plantable Sarcoma, 1699 Song, P-S. See Shieh and Song. 689 Steplewski. Herlyn, and Koprowski. 717 Singhakowinta, A. See Everson, Lippman. Soong, S-J. See Lawrence, Shingleton, Gore, and Stern, R., Wilczek, J., Thorpe, W. P., Rosenberg, Thompson, McGuire, Wittliff, De Sombre, Jen Soong, 1558 S. A., and Cannon, G. Procollagens as Markers sen, Singhakowinta. Brooks, and Neifeld, 991 Soprano, K. J. See Petralia, Soprano, Pochron, for the Cell of Origin of Human Bone Tumors. Sirica, A. E., Hwang, C. G., Sattler, G. L., and Darzynkiewicz, TrÃ¡ganos, and Baserga, 3177 325 Pitot, H. C. Use of Primary Cultures of Adult Rat Sordahl, L. A. See Carpentieri and Sordahl, 221 Sternberg, S. S. See Warrell. Chou. Gordon. Tan. Hepatocytes on Collagen Gel-Nylon Mesh to Sorof. S. See Blackburn, Andrews, Rao, and So- Roberts, Sternberg, Philips, and Young, 4546; Evaluate Carcinogen-induced Unscheduled rof, 4688 Woodcock, Chou, Tan, Sternberg, Philips, DMA Synthesis, 3259 Spang-Thomsen, M. See Vindelov. Hansen, Young, and Burchenal, 4243 Sirotnak, F. M., and Moccio, D. M. Pharmacoki- Christensen, Spang-Thomsen, Hirsch, Hansen, Stevens, F. J. See Peraino. Staffeldt. Haugen, netic Basis for Differences in Methotrexate Sen and Nissen, 4295 Lombard, Stevens, and Fry, 3268 sitivity of Normal Proliferative Tissues in the Sparkman, D. See Prashad, Rosenberg, Baskin, Stewart, D. J. See Loo, Friedman, Moore, Valdi Mouse, 1230 Sparkman, Ulrich, and Wischmeyer. 2884 vieso. Marti, and Stewart. 86 Skipper, P. L. See Kraft, Skipper, and Tannen- Sparks, R. L. See Cameron, Smith. Pool, and Stewart, D. J., Benjamin, R. S., Leavens, M., baum,2740 Sparks, 1493 Valdivieso, M., Burgess, M. A., and Bodey, G. Skipper, P. L., Tannenbaum, S. R., Thilly, W. G., Spataro, A. C. See Myers-Robfogel and Spataro, P. Phase I Study of 1-{2-Chloroethyl)-3-(2.6- Furth, E. E., and Bishop, W. W. Mutagenicity 1940 dioxo-3-piperidylM -nitrosourea (NSC 95466) of Hydroxamic Acids and the Probable Involve Speck, W. T. See Blumer, Friedman, Meyer, Fair- in Adults with Solid Tumors, 3750 ment of Carbamoylation, 4704 child, Webster, and Speck. 4599 Stewart, D. J., Leavens, M., Friedman, J., Ben Sklaroff, R. B. See Arlin, Sklaroff, Gee, Kempin, Spector, A. A. See Yoo, ChiÃ¹,Spector, Whiteaker. jamin, R. S., Moore, E. C., Bodey, G. P., Val Howard, Clarkson, and Young, 3304 Denning, and Lee, 1084 divieso, M., Burgess, M. A., Wiseman, C., and Shovsgaard, T. Circumvention of Resistance to Speyer, J. L., Collins, J. M., Dedrick, R. L., Bren- Loo, T. L. Penetration of W-(Phosphonacetyl)- Daunorubicin by N-Acetyldaunorubicin in Ehr nan, M. F., Buckpitt. A. R., Lender, H., DeVita, L-aspartate into Human Central Nervous System lich Ascites Tumor. 1077 V. T., Jr., and Myers, C. E. Phase I and Phar and Intracerebral Tumor. 3163 Sladek, N. E. See Domeyer and Sladek, 174 macological Studies of 5-Flourouracil Adminis Stewart, J. A. See Newman. Kimberly, Stewart, Slaga, T. J. See DiGiovanni, Berry, Gleason, Ki- tered Intraperitoneally, 567 and Kelley, 3621 shore, and Slaga, 1580; Iyer, Lyga, Secrist, Spiegelman, S. See Stolti, Sawyer, Nayak. Spie- Stickney, D. G. See Gerner, Holmes. Stickney, Daub, and Slaga, 1073; Verma, Slaga, Wertz, gelman, and Martin, 2730 Noterman, and Fuller, 432 Mueller, and Boutwell, 2367 Spiller, G. A. See Freeman, Spiller, and Kim, 2661 Stinson, S. F., and Lilga, J. C. Morphogenesis of Slaga, T. J., Gleason, G. L., Mills, G., Ewald, L., Spira, J., Babonits, M., Wiener, F., Ohno, S., Neoplasms Induced in the Hamster Trachea with Fu, P. P., Lee, H. M., and Harvey, R. G. Com Wirschubski, Z., Haran-Ghera, N., and Klein, N-Methyl-fV-nitrosourea, 609 parison of the Skin Tumor-initiating Activities of G. Nonrandom Chromosomal Changes in Thy- Stocco, D. M., and Hutson, J. C. Characteristics Dihydrodiols and Diol-Epoxides of Various Poly- 1-positive and Thy-1-negative Lymphomas In of Mitochondria Isolated by Rate Zonal Centrif- cyclic Aromatic Hydrocarbons. 1981 duced by 7,12-Dimethylbenzanthracene in SJL ugation from Normal Liver and Novikoff Hepa- Sloane, J. P., Ormerod, M. G., and Neville, A. M. Mice. 2609 tomas. 1486 Potential Pathological Application of Immuno- Sporn, M. B. See Newton, Henderson, and Sporn, Stock, C. C. See Schmid, Otter, and Stock. 830 cytochemical Methods to the Detection of Mi- 3413 Stockert, R. J., and Becker, F. F. Diminished crometastases. 3079 ' Spratt. J. S., Adcock, R. A., Muskovin, M., Sher- Hepatic Binding Protein for Desialylated Glyco- Slocum, H. K. See Pavelic, Slocum, Rustum, rill, W., and McKeown, J. Clinical Delivery Sys proteins during Chemical Hepatocarcinogene- Creaven, Karakousis. and Takita. 2160; Pav tem for Intraperitoneal Hyperthermic Chemo sis. 3632 elic, Slocum, Rustum, Creaven, Nowak, Karak therapy, 256 Stoker, T. A. M. See Recklies. Tiltman. Stoker, ousis, Takita. and Mittleman. 4151 Spratt, J. S., Adcock, R. A., Sherrill, W., and and Poole. 550 Smith, B. R., Plummer, J. L., Ball, L. M., and Travathen, S. Hyperthermic Peritoneal Perfu Stolti, R. L., Sawyer, R. C., Nayak, R., Spiegel Bend, J. R. Characterization of Pulmonary Ar sion System in Canines, 253 man, S., and Martin, D. S. Protection by Tes ene Oxide Biotransformation Using the Perfused Springer, E. L. Comparative Study of the Cyto- tosterone from Fluorouracil-induced Toxicity Rabbit Lung, 101 plasmic Organelles of Epithelial Cell Lines De without Loss of Anticancer Activity against Au Smith, C. A. See Kaye, Smith, and Hanawalt, 696 rived from Human Carcinomas and Nonmalig- tochthonous Murine Breast Tumors, 2730 Smith, G. L. See Knauer, Iyer, Banerjee, and nant Tissues, 803 Stone, J. P. See Shellabarger, McKnight. Stone, Smith, 4368 Staats, J. Standardized Nomenclature for Inbred and Holtzman, 1808 Smith, G. J., Ohi, V. S., and Litwack, G. Purifi Strains of Mice: Seventh Listing, 2083 Stone, J. P., Holtzman, S., and Shellabarger, C. cation and Properties of Hamster Liver Ligan- Staffeldt. E. F. See Peraino, Staffeldt, Haugen, J. Synergistic Interactions of Various Doses of dins. Glutathione S-Transferases, 1787 Lombard. Stevens, and Fry, 3268 Diethylstilbestrol and X-lrradiation on Mammary

DECEMBER 1980 4863 Author Index to Volume 40

Neoplasia in Female ACI Rats, 3966 Rat Liver, and Hepatoma HC-252, page 4677 Tsukagoshi, and Sakurai, 1707 Stone, K. R. See Shrivastav, Bonar, Stone, and Sundqvist, K. See HafstrÃ¶m, Nobin, Persson, and Takita, H. See Markus, Takita, Camiolo, Cora- Paulson, 4438; Shrivastav, Stone, Paulson, and Sundqvist, 481 santi, Evers, and Hobika, 841 ; Pavelic, Slocum, Bonar, 4443 Surjan, A. See BÃ¶rzsÃ¶nyi,TÃ¶rÃ¶k,Pinter. Surjan. Rustum. Creaven, Karakousis, and Takita. Stoner, G. D. See Theiss, Shimkin, Stoner, Kni- NÃ¡dasdi, and Roller, 2925 2160; Pavelic, Slocum, Rustum, Creaven, No azeff, and Hoppenstand, 64 Sutherland, B. M., Cimino, J. S., Delihas, N., wak, Karakousis, Takita, and Mittelman. 4151 Storme, G., and Maree!, M. M. Effect of Antican Shin, A. G., and Oliver, R. P. Ultraviolet Light- Talcott, R. E.. See Denk, Abdelfattah-Gad, Eck- cer Agents on Directional Migration of Malignant induced Transformation of Human Cells to An erstorfer. and Talcott, 2568 C3H Mouse Fibroblastic Cells in Vitro. 943 chorage-independent Growth. 1934 Talgoy, M. M. See Lam, Talgoy, and Goldenberg, Story, D. L. See Essigmann, Donahue, Story, Wo- Sutherland, B. M., Harber, L. C., and Kochevar, 3950 gan, and Brunengraber, 4085 I. E. Pyrimidine Dimer Formation and Repair in Talley, D. J. See Li, Li, Talley, Kirkman. Lin, and Stout, D. L.t and Becker, F. F. Progressive DNA Human Skin, 3181 Villee, 3854 Damage in Hepatic Nodules during 2-Acetyl- Sutherland, R. M. See Freyer and Sutherland, Tam, M. R., Green, W. R., and Nowinski, R. C. aminofluorene Carcinogenesis, 1269 3956 Cytotoxic Activities of Monoclonal Antibodies Stout, D. L., Hemminki. K., and Becker, F. F. Suzuki, E. See Mochizuki, Irving, Anjo, Wakabay- against the Envelope Proteins of Murine Leu Covalent Binding of 2-Acetylaminofluorene, 2- ashi, Suzuki, and Okada, 162 kemia Virus, 3850, Communication Aminofluorene, and N-Hydroxy-2-acetylamino- Suzuki, K. See Lee, Suzuki, Mukhtar. and Bend, Tamaoki, T. See Atryzek, Tamaoki, and Fausto, fluorene to Rat Liver Nuclear DNA and Protein 2486 3713 in Vivo and in Vitro, 3579 Suzuki, M. See Matsubara, Suzuki, and Ishida, Tamenishi, A. See Koji, Ishii, Munehisa, Kusu- Strada, S. J. See Epstein, Mills, Hersh, Strada, 873; Matsubara, Suzuki, Nakamura, Edo, and moto, Nakamura, Tamenishi, HarÃ¡, Kobayashi, and Thompson, 379; Thompson, Ross, Strada, Ishida, 2534 Tsukada, Nishi, and Hirai, 3013' Hersh, and Lavis, 1955 Suzuki, T. See Matsuzawa, Mizuno, Yamamoto, Tamiya-Koizumi, K. See Koizumi, Tamiya-Ko- Stragand, J. J., Bergerat, J-P., White, R. A., Hori, and Suzuki, 3361 izumi, Fujii, Okuda, and Kojima, 909 Hokanson, J., and Drewlnko, B. Biological and Suzuki, Y. See Chahinian, Beranek, Suzuki, Be- Tan, C. T. C. See Warrell, Chou, Gordon, Tan, Cell Kinetic Properties of a Human Colonie Ad- kesi, Wisniewski, Selikoff, and Holland. 181 Roberts, Sternberg, Philips, and Young. 4546; enocarcinoma (LoVo) Grown in Athymic Mice, Sweeney, M. J. See Worzalla and Sweeney, 1482 Woodcock, Chou, Tan, Sternberg, Philips, 2846 Swenberg, J. A., Kerns, W. D., Mitchell, R. I., Young, and Burchenal, 4243 StrÃ¤uchen,J. A., Arya, S. K., Tralka, T. S., Engel, Gralla, E. J., and Pavkov, K. L. Induction of Tanabe, S. See Nakata, Ochi, Kurisaki, Okano, L. W., and Young, N. A. Search for Retrovirus- Squamous Cell Carcinomas of the Rat Nasal Hamada, Amitani, Tanabe, Ono, and Sakamoto, like Particles in Human Breast Cancer Cells in Cavity by Inhalation Exposure to Formaldehyde 127 Culture, 3888 Vapor, 3398, Communication Tanaka, K. See Tanooka, Hoshino, Tanaka, and Strickland, J. E., Saviolakis, G. A., Weislow, 0. Sylvester, P. W. See Aylsworth. Sylvester, Leung, Nagase. 2547 S., Allen, P. T., Hellman, A., and Fowler, A. K. and Meites, 1863 Tanaka, N. See Tokita, Tanaka, Sekimoto, Ueno, Spontaneous Adrenal Tumors in the Aged, Szakal, A. K., Diwan, B. A., and Blackman, K. E. Okamoto, and Fujimura, 4287 Ovariectomized NIH Swiss Mouse without En Modulation of Immunological Competence in Tani, S. See Isohashi, Tsukanaka, Terada, Nak- hanced Retrovirus Expression, 3570 1,2-Dimethylhydrazine-sensitive SWR/J Mice anishi, Tani, and Sakamoto, 877 Strickler, G. See Brunke, Strickler, and Leboy, during Colorectal Carcinogenesis, 2475 Taniguchi, S. See Kimura, Taniguchi, Aoki, and 417 Baba, 2061 Strife, A. See Murgo, Fried, Burchenal, Vale, Tannenbaum, S. R. See Kraft, Skipper, and Tan Strife, Woodcock, Young, and Clarkson, 1543 nenbaum, 2740; Kraft and Tannenbaum. 1921 ; Strniste, G. F., Martinez, E., Martinez, A. M., and Skipper, Tannenbaum, Thilly, Furth, and Brake, R. J. Photo-induced Reactions of Taetle, R., and Koessler, A. Effects of Cyclic Bishop, 4704 Benzo(a)pyrene with DNA in Vitro, 245 Nucleotides and Prostaglandins on Normal and Tanooka, H., Hoshino, H., Tanaka, K., and Na Strobel-Stevens, J. See Brattimi, Strobel-Ste- Abnormal Human Myeloid Progenitor Prolifera gase, M. Experimental Radiation Therapy and vens, Fine, Webb, and Sarrif, 2142 tion, 1223 Apparent Radioresistance of Autochthonous Strong, J. M. See Erlichman, Strong, and Chab- Tagashira, Y. See Kawajiri, Yonekawa, Harada, Tumors Subcutaneously Induced with 3-Meth- ner, 1902 Noshiro, Omura, and Tagashira, 1652 ylcholanthrene in Mice, 2547 Stroube, R. B. See Tagnon, Blot, Stroube, Day, Taggart, B. N. See Pitelka, Hamamoto, and Tag- Tao, T-W. See Finne, Tao, and Burger, 2580 Morris, Peace, and Fraumeni, 3875 gart, 1588, 1600 Tarane, R. E. See Parshad, Sanford, Jones, Tar- Stylos, W. A. See Chirigos and Stylos, 1967 Tagnon, I., Blot, W. J., Stroube, R. B., Day, N. one, Hoffman, and Grier, 4415 Subbarao, V. See Scarpelli, Rao, Subbarao, Bov- E., Morris, L. E., Peace, B. B., and Fraumeni, Tarpley, W. G., Miller, J. A., and Miller, E. C. ersluis, Gurka, and Hollenberg, 67 J. F., Jr. Mesothelioma Associated with the Adducts from the Reaction of W-Benzoyloxy-N- Sueoka, S. See Matsukura, Kakita, Sueoka, Yosh- Shipbuilding Industry in Coastal Virginia, 3875 methyl-4-aminoazobenzene with Deoxyguano- imi, Hirata, Yokota, and Fujita. 3768 Tai, J. See Ghose, Norvell, Aquino, Belitsky, Tai, sine or DNA in Vitro and from Hepatic DNA of Sugimoto, T. See Ashley, Zbar, Hunter, Rapp, Guclu, and Blair, 3018* Mice Treated with N-Methyl- or N,W-Dimethyl-4- and Sugimoto, 4197 Takahashi, K. See Tohda, Horaguchi, Takahashi. aminoazobenzene, 2493 Sugimura, T. See Kakizoe, Komatsu, Niijimu, Ka- Oikawa, and Matsushima, 4775 Tashiro, T. See Ootsu, Kozai, Takeuchi, Ikeyama, wachi, and Sugimura, 2006; Saito, Sawamura, Takahashi, M. See Raicht, Cohen, Fazzini, Sar- Igarashi, Tsukamoto, Sugino, Tashiro, Tsuka Umezawa, Kanal, Furihata, Matsushima, and wal, and Takahashi, 403 goshi, and Sakurai, 1707 Sugimura, 2539 Takahashi, M. See Sasaki and Takahashi, 4810 Tattersall, M. H. N. See Fox, Tripp, Piddington, Sugino, Y. See Ootsu, Kozai, Takeuchi, Ikeyama, Takahashi, S. See Rao, Takahashi, and Shino- and Tattersall, 3383; Fox, Tripp, and Tattersall, Igarashi, Tsukamoto, Sugino, Tashiro, Tsuka- zuka, 592 1718 goshi, and Sakurai, 1707 Takai, S-i. See Ohtsuru. Ishii, Takai, Higashi, and Taub, R. N. See Shumak, Baker, Taub, Coleman, Suginoshita, T. See Izumi, Nagai, and Suginosh- Kosaki, 477 and the Toronto Leukemia Study Group, 4048 ita, 444 Takayama, S. See Ishikawa, Takayama. and Ide, Taylor, C. W. See Buening, Levin, Wood, Chang, Sugiura, M., Yamazoe, Y., Kamataki, T., and 2898; Ishikawa, Takayama, and Kitagawa, Lehr, Taylor. Yagi, Jerina, and Conney, 203 Kato, R. Reduction of Epoxy Derivatives of 4261 Taylor, D. D., Homesley, H. D., and Doellgast, G. Benzo(a)pyrene by Microsomal Cytochrome P- Takeichi, N. See Minami, Kasai, Mizushima, Tak- J. Binding of Specific Peroxidase-Labeled An 450, page 2910 eichi, Hosokawa, and Kobayashi, 2129 tibody to Placental-type Phosphatase on Tumor- Sugiyama, K., Tomida, M., Honma, Y., and Hoz- Takeichi, N., and Kobayashi, H. Development of derived Membrane Fragments, 4064 umi, M. Expression of a Cell Surface Glycopro- Runting Syndrome in Friend and Gross Virus- Telfer, N. See Landolph, Bhatt. Telfer, and Hei tein (pi80) Related to Cell-Substratum Adhe induced Doubly Tolerant Rats, 448 delberger, 4581 sion during Differentiation of Mouse Myeloid Takenaga, K., Hozumi, M., and Sakagami, Y. Teller, M. N., and Faanes, R. B. Association of Leukemia Cells, 3387 Effects of Retinoids on Induction of Differentia Host Immunity with 5-Fluorouracil-initiated Cure Suh, M. H. See Karasaki, Suh, Salas, and Ray tion of Cultured Mouse Myeloid Leukemia Cells, of Plasmacytoma LPC-1 in BALB/c Mice, 2790 mond, 1318 914 Templeton, M. A. See Parham and Templeton, Suit, H. D. See Overgaard. Suit, and Walker, 2045 Takenaka, K. See Yagawa, Kaku, Manabe, Yas- 1475 Suk, W. A. See Long, Suk, Snead, and Christen- umoto, Mashiba, Iribe, Yamagata. Takenaka, Terada, M. See Isohashi, Tsukanaka, Terada, sen, 3886 and Nomura, 4791 Nakanishi, Tani, and Sakamoto, 877 Sukumar, S. See Zbar, Canti, Rapp, Ashley, Suk- Takeuchi, J. See Fujita, Ito, Inoue, Yamamoto, Terasaki, T. See Miyamoto and Terasaki, 4751 umar, and Bast, 1036 Takeuchi, Shamoto, and Nagatsu, 2543 Terpstra, O. T. See Williamson, Bauer. Terpstra, Sun, A. S., and Cederbaum, A. I. Oxidoreductase Takeuchi, M. See Ootsu, Kozai, Takeuchi, Ikey Ross, and Malt, 538 Activities in Normal Rat Liver, Tumor-bearing ama, Igarashi, Tsukamoto, Sugino, Tashiro, Terry, W. D. See Leserman, Weinstein, Moore,

4864 CANCER RESEARCH VOL. 40 Author Index to Volume 40

and Terry, 4768 and Their Evaluation as a Test System, 4775 Tsakeres, Adams, and Ullrich, 2153 Teulings, F. A. G.. van Gilse, H. A., Henkelman, Tokita, H., Tanaka, N., Sekimoto, K., Ueno, T., Tseng, B. Y. See Ingraham, Tseng, and Goulian, M. S., Portengen, H., and Alexieva-Figusch, J. Okamoto, K., and Fujimura, S. Experimental 998 Estrogen, Androgen, Glucocorticoid, and Pro Model for Combination Chemotherapy with Met- Tseng, J. S. See Rosen, Calvert, Weintraub, gesterone Receptors in Progestin-induced ronidazole Using Human Uterine Cervical Car Tseng, and Rabson, 4325 Regression of Human Breast Cancer, 2557 cinomas Transplanted into Nude Mice, 4287 Tseng, M. T. Ultrastructure of the Hormone-de Tew, K. D., Schein, P. S.. Lindner, D. J., Wang, Tomaszewski, J. E. See Bigger, Tomaszewski, pendent N-Nitrosomethylurea-induced Mam A. L., and Smulson, M. E. Influence of Hydro- Andrews, and Dipple, 655 mary Carcinoma of the Rat. 3112 cortisone on the Binding of Nitrosoureas to Nu Tomatis, L. See Althouse, Huff, Tomatis. and Wil- Tsuchimoto, K. See Morizane. Kumagai. Tsuchi- clear Chromatin Subfractions, 3697 bourn, 1; Zajdela, Croisy, Barbin. Malaveille, moto, Watanabe, and Tsuchiya. 2928 Thaete, L. G. See McMillan, Thaete, Hooker, and Tomatis, and Bartsch, 352 Tsuchiya, M. See Morizane, Kumagai, Tsuchi Roos. 1419 Tomazic, V., Ehrke, M. J., and Mihich, E. Modu moto. Watanabe, and Tsuchiya, 2928 Thakker, D. R. See Wood. Chang, Huang, Levin, lation of the Cytotoxic Response against Allo- Tsuda, H., Lee, G., and Farber, E. Induction of Lehr, Kumar, Thakker, Yagi, Jerina, and Con- geneic Tumor Cells in Culture by Adriamycin, Resistant Hepatocytes as a New Principle for a ney, 1985 2748 Possible Short-Term in Vivo Test for Carcino Theilen, G. H. See Lutz, Pedersen, Higgins, Tomida, M. See Sugiyama, Tomida. Honma, and gens, 1157 HÃ¼bscher,Troy, and Theilen, 3642 Hozumi, 3387; Yamamoto, Tomida, and Hoz- Tsui-Collins, A. L. See Yu, Lannin, Tsui-Collins, Theiss, J. C., Arnold, L. J., and Shimkin, M. B. umi, 4804 and McKhann, 2756 Effect of Commercial Saccharin Preparations on Tomida, M., Yamamoto, V.. and Hozumi, M. Stim Tsukada, K. See Okada, Watanabe. and Tsukada, Urethan-induced Lung Tumorigenesis in Strain ulation by Interferon of Induction of Differentia 2895 A Mice, 4322, Communication tion of Mouse Myeloid Leukemic Cells, 2919 Tsukada, Y. See Koji, Ishii, Munehisa, Kusumoto, Theiss, J. C., Shimkin, M. B., Stoner, G. D., Tompkins, W. A. F. See Rosenthal, Tompkins, Nakamura, Tamenishi, HarÃ¡, Kobayashi, Tsu Kniazeff, A. J., and Hoppenstand, R. 0. Effect and Rawls, 4744 kada, Nishi. and Hirai, 3013' of Lactate Dehydrogenase Virus on Chemically Tonali, P. See Ranelletti, lacobelli, Carmignani, Tsukagoshi, S. See Ootsu, Kozai, Takeuchi. Ikey- Induced Mouse Lung Tumorigenesis, 64 Sica. Natoli, and Tonali, 2020 ama, Igarashi. Tsukamoto. Sugino, Tashiro. Theologides, A. See Howard, Theologides. and Tong, M. See Chan, Chlebowski, Tong. Chen, Tsukagoshi, and Sakurai, 1707; Tsuruo. Nagan- Sheppard, 2695 Gross, and Bateman, 1263 uma, lida. and Tsukagoshi, 4758; Yoshida, Ki- Thilly, W. G. See Skipper, Tannenbaum, Thilly. Topping, D. C., and Nettesheim, P. Promotion- yohara. Fukui, Atsumi, Ogino, Inaba, Tsukago Furth, and Bishop, 4704 like Enhancement of TrachÃ©alCarcinogenesis shi, and Sakurai, 3810 Thomas, G. See Hashem, Bootsma, Keijzer. in Rats by 12-O-Tetradecanoyl-phorbol-13-ace Tsukamoto, K. See Ootsu, Kozai, Takeuchi. Ikey- Greene, Coriell, Thomas, and Cleaver, 13 tate, 4352 ama, Igarashi, Tsukamoto, Sugino, Tashiro. Thomas, P. E. See Wood, Chang, Levin, Ryan, Torlontano, G. See Fioritoni, Bertolini, Torlon- Tsukagoshi, and Sakurai, 1707 Thomas. Croisy-Delcey, Utah, Yagi, Jerina, and tano. and Revoltella, 866 Tsukanaka, K. See Isohashi, Tsukanaka. Terada. Conney, 2876; Wood, Levin, Chang, Huang, TÃ¶rÃ¶k,G. See BÃ¶rzsÃ¶nyi,TÃ¶rÃ¶k,Pinter, Surjan. Nakanishi, Tani, and Sakamoto, 877 Ryan, Thomas, Lehr, Kumar, Koreeda, Akagi, NÃ¡dasdi, and Roller. 2925 Tsunematsu, Y. See Sasaki, Tsunematsu. Utsu- Utah, Dansette, Yagi. Jerina, and Conney, 642 Toronto Leukemia Study Group See Shumak. nomiya. and Utsumi, 4796 Thompson, E. B. See Everson, Lippman. Thomp Baker, Taub, Coleman, and the Toronto Leu Tsuruo, T., Naganuma, K., lida, H., and Tsuka son, McGuire, Wittliff, De Sombre, Jensen, Sin- kemia Study Group, 4048 goshi, S. Lymph Node Metastasis and Effects ghakowinta. Brooks, and Neifeld, 991 Toyama, Y. See Payette, Biehl, Toyama, Holtzer, of 1-ÃŸ-D-Arabinofuranosylcytosine. 5-Fluorou- Thompson, L. H., Baker, R. M., Carrano, A. V., and Holtzer, 2465 racil, and Their Lipophilic Derivatives in an Ex and Brookman, K. W. Failure of the Phorbol TrÃ¡ganos, F. See Petralia, Soprano, Pochron. perimental Model System Using P388 Leuke Ester 12-O-Tetradecanoylphorbol-13-acetate Darzynkiewicz, TrÃ¡ganos, and Baserga, 3177 mia, 4758 to Enhance Sister Chromatid Exchange, Mitotic TrÃ¡ganos, F., Evenson, D. P., Staiano-Coico, L., Tucker, K. A. See Green, Pretlow, Tucker, Brad Segregation, or Expression of Mutations in Darzynkiewicz, Z., and Melamed, M. R. Action ley, Cook, Pitts, and Pretlow, 1791 Chinese Hamster Cells, 3245 of Dihydroxyanthraquinone on Cell Cycle Pro Tung, K. S. K. See Kaszubowski, Husby, Tung, Thompson, M. P. See Singh. Grigor. and Thomp gression and Survival of a Variety of Cultured and Williams, 4648 son, 1699 Mammalian Cells, 671 Turco, M. C. See Colletta, Di Fiore, Ferrentino, Thompson, W. J. See Epstein, Mills, Hersh. TrÃ¡ganos, F., Staiano-Coico, L., Darzynkiewicz, Pietropaolo, Turco, and Vecchio, 3369 Strada, and Thompson, 379 Z., and Melamed, M. R. Effects of Ellipticine on Turcot-Lemay, L., and Kelly, P. A. Characteriza Thompson, W. J., Ross, C. P., Strada, S. J., Cell Survival and Cell Cycle Progression in Cul tion of Estradiol, Progesterone, and Prolactin Hersh, E. M., and Lavis, V. R. Comparative tured Mammalian Cells, 2390 Receptors in Nitrosomethylurea-induced Mam Analyses of Cyclic Adenosine 3':5'-Monophos- Traish, A. See MÃ¼ller,Sheard, Traish, and Wotiz. mary Tumors and Effect of Antiestrogen Treat phate Phosphodiesterases of Human Peripheral 2941 ment on the Development and Growth of These Blood Monocytes and Cultured P388D, Cells, Tralka, T. S. See StrÃ¤uchen, Arya, Tralka, Engel, Tumors, 3232 1955 and Young, 3880 Turner, D. S. See Brinkley. Beali, Wible. Mace. Thorgeirsson, S. S. See Johnson, Levitt, Muller- Tramontano, D. See Vescia, Tramontano, Au Turner, and Cailleau, 3118 gusti-Tocco, and D'Alessio, 3740 Eberhard, and Thorgeirsson, 4456 Tuthill, R. See Herlyn, Clark, Mastrangelo. Thornthwaite, J. T. See Allen and Thornthwaite, Travathen, S. See Spratt. Adcock. Sherrill, and Guerry. Elder, LaRossa. Hamilton, Bondi, Tut 4059 Travathen, 253 hill, Steplewski, and Koprowski, 3602 Thorpe, W. P. See Stern, Wilczek, Thorpe, Ro Trenbeath, T. P. See Huggins, Trenbeath, Sher- Tuttle, M. A. See MarneÂ«and Tuttle, 276 senberg, and Cannon, 325 blom, Howard, and Carraway, 1873 Tveit, K. M., Fodstad, 0., Brogger, A., and Thuning, C. A., Bakir, N. A., and Warren, J. Trend, B. See Wang, Trend, Bronson, and Fraley, Olsnes, S. Human Embryonal Carcinoma Grown Synergistic Effect of Combined Hyperthermia 796 in Athymic Mice and in Vitro, 949 and a Nitrosourea in Treatment of a Murine Trent, J. M. See Von Hoff, Casper. Bradley, Trent, Tyagi, A. K., and Cooney, D. A. Identification of Ependymoblastoma, 2726 Hodach, Reichert, Makuch, and Altman, 3591 the Antimetabolite L-Alanosyl-Aicor in Tumors Tiltman, K. J. See Recklies, Tiltman, Stoker, and Trentin, J. J. See Nasrallah, Gallagher, Priest, and Assessment of Its Inhibition of Adenylosuc- Poole, 550 and Trentin, 4159 cinate Synthetase. 4390 Titus, G. A. See Livingston, Titus, and Heilbrun. Tresp, N. M. See Weeks, Allaben. Tresp, Louie, Tzeng, D. Y. See Olah, Lui. Tzeng, and Weber. 2209; Osborne, Hamilton, Titus, and Livingston. Lazear, and King, 1204 2869 2361 Tripp, E. H. See Fox. Tripp, Piddington, and Tat- Tkeshelashvili, L. K., Shearman, C. W., Zakour, tersall, 3383; Fox, Tripp, and Tattersall, 1718 U R. A., Koplitz, R. M., and Loeb, L. A. Effects of Trouet, A. See Jaenke, Deprez-DeCampeneere, Arsenic, Selenium, and Chromium on the Fidel and Trouet, 3530 Uchida. N. See Kitamura, Uchida, Hayata, Yama- ity of DNA Synthesis, 2455 Trown, P. W., Palleroni, A. V., Bohoslawec, 0., guchi, Okamoto, Narita, and Matsumoto, 4781 Tobler, J., Watts, M. T., and Fu, J-j. L. An in Vitro Richelo, B. N., Halpern, J. M., Gizzi, N., Geiger, Ueno, T. See Tokita, Tanaka, Sekimoto. Ueno, and in Vivo Investigation of Three Surface-active R., Lewinski, C., Machlin, L. J., Jetten, A., and Okamoto, and Fujimura, 4287 Agents as Modulators of Cell Proliferation, 1173 Jetten, M. E. R. Relationship between Binding Ugazio, G. See Giovarelli, Padula, Ugazio, Forni, Todaro, G. J. See Keski-Oja and Todaro, 4722 Affinities to Cellular Retinoic Acid-binding Pro and Cavallo, 3745 Toh, B. H. See Hard, Clarke, and Ton, 3728 tein and in Vivo and in Vitro Properties for 18 Ullman, B. See Maybaum, Ullman, Mandel, Day, Tohda, H., Horaguchi, K., Takahashi, K., Oi- Retinoids, 212 and Sadee, 4209 kawa, A., and Matsushima, T. Epstein-Burr Troy, F. A. See Lutz, Pedersen. Higgins. Ullrich, R. L. See Kennel, Lankford, Foote, Tsak Virus-Transformed Human Lymphoblastoid HÃ¼bscher,Troy, and Theilen, 3642 eres, Adams, and Ullrich, 2153 Cells for Study of Sister Chromatid Exchange Tsakeres, F. S. See Kennel, Lankford, Foote. Ulrich, C. See Prashad. Rosenberg. Baskin,

DECEMBER 1980 4865 Author Index to Volume 40

Sparkman, Ulrich, and Wischmeyer, 2884 K. Inhibition by Prostaglandin Synthesis Inhibi Chromosomes 6 and 14, page 4512 Umezawa, K. See Saito, Sawamura, Umezawa, tors of the Induction of Epidermal Ornithine De- Waksvik, H. See Moan, Waksvik, and Christen Kanai, Furihata, Matsushima, and Sugimura, carboxylase Activity, the Accumulation of Pros- sen, 2915 2539 taglandins, and Tumor Promotion Caused by Walborg, E. F., Jr. See Glenney, Kaulfus, Mc- Urano, M., and Cunningham, M. Insignificant Tu 12-O-Tetradecanoylphorbol-13-acetate, 308 Intyre, and Walborg, 2853 mor Bed Effect after Pretransplantation Hyper- Verma, A. K., Slaga, T. J., Wertz, P. W., Mueller, Walker, A. M. See Overgaard, Suit, and Walker, thermia, 26 G. C, and Boutwell, R. K. Inhibition of Skin 2045 Urano, M., and Rice, L. Thermal Sensitivity of Tumor Promotion by Retinole Acid and Its Me Walker, B. See Langenbach, Gingilli, Kuszynski, Murine Tumor Cells and Hyperthermic Tumor tabolite 5,6-Epoxyretinoic Acid, 2367 Walker, Nagel, and Pour, 3463 Eradication. Correspondence re: M. Urano, H. Vescia, S., Tramontano, D., Augusti-Tocco, G., Walker, M. J. See Chaudhuri, Walker, Beattie, and D'Alessio, G. In Vitro Studies on Selective D. Suit. P. Dunn, T. Lansdale, and R. S. Sedla- and Das Gupta, 861 cek. Enhancement of the Thermal Response of Inhibition of Tumor Cell Growth by Seminal Ri- Walker, R. A. See Wilson, Woods, Walker, and Animal Tumors by Corynebacterium parvum. bonuclease, 3740 Howell, 486 Cancer Res., 39: 3454-3457, 1979, page 959, Vesselinovitch, S. D., Itze, L., Mihailovich, N., Walsh, C. T., Craig, R. W., and Agarwal, R. P. Letter to the Editor and Rao, K. V. N. Modifying Role of Partial Increased Activation of 1-/8-D-Arabinofuranosyl- Urban, J. L. See Ferguson and Urban, 1255 Hepatectomy and Gonadectomy in Ethylnitro- cytosine by Hydroxyurea in L1210 Cells, 3286 Urban, R. W., Edwards, B. S., and Segal, W. sourea-induced Hepatocarcinogenesis, 1538 Walton, L. A. See Vesterinen, Nedrud, Collier, Tumor-immunotherapeutic Efficacy of Serratia Vesterinen, E. H., Nedrud, J. G., Collier, A. M., Walton, and Pagano, 512 marcescens Polyribosomes, 1501 Walton, L. A., and Pagano, J. S. Explanation Wang, A. L. See Tew, Schein, Lindner, Wang, and Ushio, Y. See Shimizu, Ushio, Hayakawa, and and Subculture of Epithelial Cells from Human Smulson, 3697 Mogami. 1341 Uterine Ectocervix, 512 Wang, B. S. See Steele, Wang, Richie, Wilson, Utsumi, J. See Sasaki, Tsunematsu, Utsunomiya. Vietti, T. See Razek, Valeriote, and Vietti, 2835 Ervin, Yankee, FallÃ³n, and Mannick, 2377; and Utsumi, 4796 Viikari, S. See HÃ¤kkinen,Heinonen, Inberg, JÃ¤rvi, Yang, Steele, Wang, and Mannick, 1762 Utsunomiya, J. See Sasaki, Tsunematsu, Utsu Vaajalahti, and Viikari, 4308 Wang, B. S., McLoughlin, G. A., Richie, J. P., nomiya, and Utsumi, 4796 Viksler, V. K. See Lavrovsky and Viksler, 3252 and Mannick, J. A. Correlation of the Produc Vilcek, J. T. See Bart, Porzio, Kopf, Vilcek, tion of Plasminogen Activator with Tumor Me Cheng, and Farcet, 614 tastasis in B16 Mouse Melanoma Cell Lines, Villee, C. A. See Li, Li, Talley, Kirkman, Lin, and 288 Villee, 3854 Wang, M. C. See Kuriyama. Wang, Papsidero, Vaage, J. Inherent Changes in the in Vivo Growth Vindelov, L. L., Hansen, H. H., Christensen, I. J., Killian, Shimano, Valenzuela, Nishiura, Murphy, Characteristics of C3H/He Mammary Carcino Spang-Thomsen, M., Hirsch, F. R., Hansen, and Chu, 4658; Papsidero, Wang, Valenzuela, mas, 3495 M., and Nissen, N. I. Clonal Heterogeneity of Murphy, and Chu, 2428 Vaajalahti, P. See HÃ¤kkinen, Heinonen, Inberg, Small Cell Anaplastic Carcinoma of the Lung Wang, N., Trend, B., Bronson, D. L., and Fraley, Jarvi, Vaajalahti, and Viikari, 4308 Demonstrated by Flow Cytometric DMA Analy E. E. Nonrandom Abnormalities in Chromosome Vaitkevicius, V. K. See Fraile, Baker, Buroker, sis, 4295 1 in Human Testicular Cancers, 796 Horwitz, and Vaitkevicius, 2223 Visser, L. See Macnab, Visser, Jamieson, and Wang, T-c. V., and Cerutti, P. A. Effect of For Valdivieso, M. See Loo, Friedman, Moore, Valdi Hay, 2074 mation and Removal of Aflatoxin Bi:DNA Ad- vieso, Marti, and Stewart, 86; Stewart, Benja Vives, C. See Drosdowsky, Edery, Guggiari, ducts in 10T'/2 Mouse Embryo Fibroblasts on min, Leavens, Valdivieso, Burgess, and Bodey, Montes-Rendon, Rudali, and Vives, 1674 Cell Viability, 2904 3750; Stewart, Leavens, Friedman, Benjamin, Von Hoff, D. D. See Bradley, Reichert, Brennan. Wang, Y-M., Madanat, F. F., Kimball, J. C., Moore, Bodey, Valdivieso, Burgess, Wiseman, and Von Hoff, 3694 Gleiser, C. A., Ali, M. K., Kaufman, M. W., and and Loo, 3163 Von Hoff, D. D., Casper, J., Bradley, E., Trent, J. van Eys, J. Effect of Vitamin E against Adria- Vale, K. L. See Murgo, Fried, Burchenal, Vale, M., Hodach, A., Reichert, C., Makuch, R., and mycin-induced Toxicity in Rabbits, 1022 Strife, Woodcock, Young, and Clarkson, 1543 Altman, A. Direct Cloning of Human Neuroblas Wanson, J-C., Bernaert, D., Penasse, W., Mos- Valenzuela, L. A. See Kuriyama, Wang, Papsi- toma Cells in Soft Agar Culture, 3591 selmans, R., and Bannasch, P. Separation in dero, Killian, Shimano, Valenzuela, Nishiura, Von Hoff, D. D., Pollard, E., KÃ¼hn,J., Murray, E., Distinct Subpopulations by Elutriation of Liver Murphy, and Chu, 4658; Papsidero, Wang, Val and Coltman, C. A., Jr. Phase I Clinical Inves Cells following Exposure of Rats to N-Nitroso- enzuela, Murphy, and Chu, 2428 tigation of 1,4-Dihydroxy-5,8-bis({{2-[(2-hy- morpholine, 459 Valeriote, F. See Razek, Valeriote, and Vietti, droxyethyl)amino]ethyl} amino)} -9,10-anthra- Warkany, J. See Kalter, Mandybur, Ormsby, and 2835 cenedione Dihydrochloride (NSC 301739), a Warkany, 3973 van Beek, A. A. M. See Bom-van Noorloos. van New Anthracenedione, 1516 Warnaar, S. O. See Herbrink, Moen, Brouwer, Beek, and Melief, 2890 von Kleist, S. U. Diagnostic Significance of Tumor and Warnaar, 166 van Doom, A. B. D. See Meerman, van Doom, Markers, 2977' Warrell, R. P., Jr., Chou, T-C., Gordon, C., Tan, and Mulder, 3772 Vose, C. W. See Coombs, Bhatt, Kissonerghis, C., Roberts, J., Sternberg, S. S., Philips, F. S., VandrÃ©, D. D. See Nelson-Rees, Vandre, and and Vose, 882 and Young, C. W. Phase I Evaluation of Succi- Montgomery. 1761; Shepherd, VandrÃ©.Elting, Vuthiganon, C. See Auda, Vuthiganon, and Elias, nylated Acinetobacter Glutaminase-Asparagi- and Montgomery, 225 2829 nase in Adults, 4546 Van Duuren, B. L. See Banerjee, Van Ouuren, and Warren, J. See Thuning, Bakir, and Warren, 2726 Oruambo, 2170 Warren, J. R. See Reddy, Rao, Warren, Qureshi, van Eys, J. See Wang, Madanat, Kimball, Gleiser, W and Christensen, 3443 Ah. Kaufman, and van Eys, 1022 Warren, J. R., Simmon, V. F., and Reddy, J. K. van Gilse, H. A. See Teulings. van Gilse, Henkel- Waalkes, T. P., Abeloff, M. D., Woo, K. B., Ettin- Properties of Hypolipidemic Peroxisome Prolif- man, Portengen, and Alexieva-Figusch, 2557 ger, D. S., Ruddon, R. W., and Aldenderfer, P. erators in the Lymphocyte [3HTThymidine and van Nagell, J. R., Jr., Kim, E., Casper, S., Primus, Carcinoembryonic Antigen for Monitoring Pa Salmonella Mutagenesis Assays, 36 F. J., Bennett, S., DeLand, F. H., and Golden tients with Small Cell Carcinoma of the Lung Watanabe, S., Shimosato, Y., Kuroki, M., Sato, berg, D. M. Radioimmunodetection of Primary during Treatment, 4420 Y., and Nakajima, T. Transplantability of Human and Metastatic Ovarian Cancer Using Radiola- Waddell, W. J., and Marlowe, C. Localization of Lymphoid Cell Line, Lymphoma, and Leukemia [I4C]Nitrosonornicotine in Tissues of the Mouse, beled Antibodies to Carcinoembryonic Antigen, in Splenectomized and/or Irradiated Nude 502 3518 Mice, 2588 Varakis, J. N. See Peterson. Varakis, and Chesh Wahren, B., Gahrton, G., and HammarstrÃ¶m, S. Watanabe, T. See Morizane, Kumagai, Tsuchi- ire, 3130 Nonspecific Cross-Reacting Antigen in Normal moto, Watanabe, and Tsuchiya, 2928 Varghese, A. J., and Whitmore, G. F. Binding to and Leukemic Myeloid Cells and Serum of Leu- Watanabe, Y. See Okada, Watanabe, and Tsu- Cellular Macromolecules as a Possible Mecha kemic Patients, 2039 kada, 2895 nism for the Cytotoxicity of Misonidazole, 2165 Wainfan, E., Brody, H., Relyea, N. M., and Balis, Watanuki, M., and Sakaguchi, K. Selective Inhi Vaughan, M. See Dobrossy, Pavelic, Vaughan, M. E. Comparisons of Liver Transfer RNA Meth- bition by Benzaldehyde of the Uptake of Nu- Porter, and Bernacki, 3281 yltransferase and Adenosylmethionine Decar- cleosides and Sugar into Simian Virus 40-trans- Vaught, J. B. See Gurtoo, Vaught, Mannello, Pai- boxylase Activities of Male and Female Rats, formed Cells, 2574 gen, Gessner, and Bolanowska, 1305 620 Watkins, W. M. See Kuhns, Oliver, Watkins. and Vecchio, G. See Colletta, Di Fiore, Ferrentino, Wakabayashi, Y. See Mochizuki, Irving, Anjo, Greenwell, 268 Pietropaolo, Turco, and Vecchio, 3369 Wakabayashi, Suzuki, and Okada, 162 Wattenberg, L. W. Inhibition of Polycyclic Aro Verma, A. K. See Weekes, Verma, and Boutwell, Wake, N., Hreshchyshyn, M. M., Piver, S. M., matic Hydrocarbon-induced Neoplasia by So 4013 Matsui, S-i., and Sandberg, A. A. Specific Cy- dium Cyanate, 232. See a/so Lam, Fladmoe, Verma, A. K., Ashendel, C. L., and Boutwell, R. togenetic Changes in Ovarian Cancer Involving Hochalter, and Wattenberg, 2824

4866 CANCER RESEARCH VOL. 40 Author Index to Volume 40

Wattenberg, L. W., Coccia, J. B., and Lam, L. K. Jones, 2796 Winand, J. See Malaisse, Sener. Herchuelz, Car- T. Inhibitory Effects of Phenolic Compounds on Wheeler, G. P., Alexander, J. A., and Adamson, pinelli. Poloczek, Winand, and Castagna, 3827 Benzo(a)pyrene-induced Neoplasia, 2820 D. J. Effects of N,A/'-Bis(2-chloroethyl)-N-nitro- Wirschubski, Z. See Spira. Babonits, Wiener. Watts, M. T. See Tobler, Watts, and Fu, 1173 sourea and 2-[3-<2-Chloroethyl)-3-nitrosou- Ohno, Wirschubski, Haran-Ghera, and Klein, Webb, M. See Brattain, Strobel-Stevens, Fine, reido]-2-deoxy-D-glucopyranose upon the Pro 2609 Webb, andSarrif, 2142 liferation. DMA Synthesis, and Viability of Cul Wischmeyer, B. See Prashad. Rosenberg. Bas Weber, G. See Jackson, LuÃ,Boritzki, Morris, and tured Sensitive and Resistant L1210 Cells, kin. Sparkman, Ulrich, and Wischmeyer, 2884 Weber, 1286; Kizaki, Morris, and Weber, 3339; 3723 Wiseman, C. See Stewart, Leavens, Friedman. Kizaki, Williams, Morris, and Weber, 3921; Whidden, M. A. See Jackson, Krance, Edwards, Benjamin, Moore. Bodey, Valdivieso, Burgess, Olah, Lui. Tzeng, and Weber, 2869 Whidden. and Gauthier, 667 Wiseman, and Loo. 3163 Webster, L. T., Jr. See Blumer, Friedman, Meyer, White, J. C. See Fry, White, and Goldman, 3669; Wislocki, P. G., Gadek, K. M., Chou, M. W., Fairchild, Webster, and Speck, 4599 Gewirtz, White, Randolph, and Goldman, 573 Yang, S. K., and Lu, A. Y. H. Carcinogenicity Weekes, R. G., Verma, A. K., and Boutwell, R. K. White, J. C., Carchman, R. A., Fry, D. W., and and Mutagenicity of the 3,4-Dihydrodiols and Inhibition by Putrescine of the Induction of Epi Goldman, I. D. Relationship between Membrane Other Metabolites of 7.12-Dimethylbenz- dermal Ornithine Decarboxylase Activity and Transport of Methotrexate and Endogenous (a)anthracene and Its Hydroxymethyl Deriva Tumor Promotion Caused by 12-O-Tetradeca- Cyclic Adenosine 3':5'-Monophosphate in the tives. 3661 noylphorbol-13-acetate, 4013 Ehrlich Ascites Tumor, 2400 Wisniewski, L. See Chahinian. Beranek, Suzuki, Weeks, C. E.. Allaben, W. T., Tresp, N. M., Louie, White, P. See Greenberg, Caruana, Holcomb, Bekesi, Wisniewski, Selikoff. and Holland, 181 S. C., Lazear, E. J., and King, C. M. Effects of Greenberg, Parker, Louis, and White, 439 Wittlitf, J. L. See Everson, Lippman, Thompson, Structure of N-Acyl-W-2-fluorenylhydroxyla- White, R. A. See Stragand, Bergerat, White. Hok- McGuire, Wittliff, De Sombre, Jensen, Singhak- mines on Arylhydroxamic Acid Acyltransferase, anson. and Drewinko, 2846 owinta. Brooks, and Neifeld. 991 Sulfotransferase, and Deacylase Activities, and Whiteaker, R. S. See Yoo, ChiÃ¹, Spector, Whi- Wodinsky, I. See Clement, Gorman, Wodinsky, on Mutations in Salmonella typhimurium TA teaker. Denning, and Lee, 1084 Catane, and Johnson. 4165; Ganapathi, Kris- 1538, page 1204 Whitehead, J. S., and Kim, Y. S. An Inhibitor of han, Wodinsky, Zubrod, and Lesko, 630 Weichselbaum, R. See West, Weichselbaum, and Lymphocyte Proliferation Produced by a Human Wogan, G. N. See Essigmann, Donahue, Story, Little, 3665 Colonie Adenocarcinoma Cell Line in Culture, Wogan, and Brunengraber. 4085; Groopman, Weichselbaum, R. R., Nove, J., and Little, J. B. 29 Busby, and Wogan, 4343 X-Ray Sensitivity of Fifty-three Human Diploid Whitehead, R. See Findlay, Michelangeli. Eisman, Wojcieszyn, J. W. See Papsidero. Wojcieszyn, Fibroblast Cell Strains from Patients with Char Frampton, Moseley, Maclntyre, Whitehead, and Horoszewicz, Leong, Murphy, and Chu. 3032* acterized Genetic Disorders, 920 Martin, 4764 Wolff, S. See Morimoto and Wolff, 1189 Weigent, D. A., and Nelson, J. A. Reduction of Whitfield, J. F. See Boynton and Whitfield, 4541 Woo, K. B. See Waalkes, Abeloff, Woo. Ettinger. DMA Transforming Activity in Culture by 6-Mer- Whitmore, G. F. See Varghese and Whitmore, Ruddon, and Aldenderfer, 4420 captopurine, 4381 2165 Wood, A. W. See Buening, Levin, Wood, Chang. Weinstein, I. B. See Ivanovic and Weinstein, Wibe, E. Age-dependent Cell Inactivation by Vin- Lehr, Taylor. Yagi. Jerina. and Conney. 203; 3508; Laskin, Laskin, Weinstein, and Carch- cristine Alone or in Combination with 1-Propar- Levin. Wood, Chang, Utah, Croisy-Delcey, Yagi, man, 1028; Poirier, Santella, Weinstein, Grun- gyl-5-chloropyrimidin-2-one. 2069 Jerina. and Conney. 3910 berger, and Yuspa. 412 Wible, L. J. See Brinkley. Beali. Wible, Mace, Wood, A. W., Chang, R. L., Huang, M-T., Levin, Weinstein, J. N. See Leserman, Weinstein, Turner, and Cailleau, 3118 W., Lehr, R. E., Kumar, S., Thakker, D. R., Moore, and Terry, 4768 Wick, M. M. Levodopa and Dopamine Analogs as Yagi, H., Jerina, D. M., and Conney, A. H. Weinstein, J. N., Magin, R. L., Cysyk, R. L., and DMA Polymerase Inhibitors and Antitumor Mutagenicity of Benzo(e)pyrene and Triphen- Zaharko, D. S. Treatment of Solid L1210 Mu Agents in Human Melanoma. 1414 ylene Tetrahydroepoxides and Diol-Epoxides in rine Tumors with Local Hyperthermia and Tem Widder, K. J., Senyei, A. E., and Ranney, D. F. Bacterial and Mammalian Cells, 1985 perature-sensitive Liposomes Containing Meth- In Vitro Release of Biologically Active Adriamy- Wood, A. W., Chang, R. L., Levin, W., Ryan, D. otrexate, 1388 cin by Magnetically Responsive Albumin Micro- E., Thomas, P. E., Croisy-Delcey, M., Ittah, Y., Weintraub, B. D. See Rosen, Calvert, Weintraub, spheres, 3512 Yagi, H., Jerina, D. M., and Conney, A. H. Tseng, and Rabson. 4325 Wiebkin, P., and Prough, R. A. Oxidative Metab Mutagenicity of the Dihydrodiols and Bay-Re Weiser, M. M. See Porter, Dworaczyk, Ganis, and olism of N-lsopropyl-a-<2-methylazo)-p-toluam- gion Diol-Epoxides of Benzo(c)phenanthrene in Weiser, 2330 ide (Azoprocarbazine) by Rodent Liver Micro- Bacterial and Mammalian Cells, 2876 Weislow, O. S. See Strickland, Saviolakis, Weis- somes, 3524 Wood, A. W., Levin, W., Chang, R. L., Huang, M- low, Allen, Hellman, and Fowler, 3570 Wiener, F. See Spira, Babonits, Wiener, Ormo, T., Ryan, D. E., Thomas, P. E., Lehr, R. E., Weizsaecker, M., and Deen, D. F. Effect of Wirschubski, Haran-Ghera, and Klein. 2609 Kumar, S., Koreeda, M., Akagi, H., Ittah, Y., Feeder Cell-released Substances on the Sur Wiernik, P. H. See Chiuten. Wiernik, Zaharko. Dansette, P., Yagi, H., Jerina, D. M., and Con vival of Clonogenic 9L Cells after Treatment with and Edwards. 818 ney, A. H. Mutagenicity and Tumor-initiating Antimetabolites, 3202 Wilbourn, J. See Althouse, Huff, Tomatis, and Activity of Cyclopenta(c.d)pyrene and Structur Welsch, C. W., Brown, C. K., Goodrich-Smith, Wilbourn. 1 ally Related Compounds. 642 M., Chiusane, J., and Moon, R. C. Synergistic Wilczek, J. See Stern, Wilczek, Thorpe, Rosen Woodcock, T. See Murgo. Fried. Burchenal. Vale. Effect of Chronic Prolactin Suppression and berg, and Cannon, 325 Strife, Woodcock, Young, and Clarkson, 1543 Retinoid Treatment in the Prophylaxis of W- Williams, J. C. See Kizaki, Williams, Morris, and Woodcock, T. M., Chou, T-C., Tan, C. T. C., Methyl-W-nitrosourea-induced Mammary Tu- Weber, 3921 Sternberg, S. S., Philips, F. S., Young, C. W., morigenesis in Female Sprague-Dawley Rats. Williams, R. C., Jr. See Kaszubowski. Husby, and Burchenal, J. H. Biochemical, Pharmaco 3095 Tung, and Williams, 4648 logical, and Phase I Clinical Evaluation of Pseu- Welsh, C. J. See Cabot, Welsh. Callaham. and Williamson, R. C. N., Bauer, F. L. R., Terpstra, doisocytidine, 4243 Huberman, 3674 O. T., Ross, J. S., and Malt, R. A. Contrasting Effects of Subtotal Enteric Bypass, Enterec- Woodman, P. W., Sarrif, A. M., and Heidelber Weltz, M. D. See Ozols. Willson. Weltz, Grotzin- tomy, and Colectomy on Azoxymethane-in- ger, C. Specificity of Pyrimidine Nucleoside ger, Myers, and Young, 4109 Phosphorylases and the Phosphorolysis of 5- duced Intestinal Carcinogenesis. 538 Weppner, W. A., and Coggin, J. H.. Jr. Antigenic Fluoro-2'-deoxyuridine, 507 Willson, J. K. V. See Ozols. Willson, Grotzinger, Similarity between Plasma Membrane Proteins Woods, K. L. See Wilson. Woods. Walker, and and Young, 2743; Ozols, Willson, Weltz, Grot of Fetal Hamster Cells and Simian Virus 40 Howell, 486 zinger, Myers, and Young. 4109 Tumor Surface Antigens, 1380 Wilson, C. B. See Fulton, Levin. Lubich. Wilson, Woolley, P. See Rahman. Kessler, More. Sikic, Wertz, P. W. See Verma, Slaga, Wertz, Mueller, and Marlon, 3293 Rowden, Woolley, and Schein, 1532 and Boutwell, 2367 Wilson, E. L., Becker, M. L. B., Hoal, E. G., and Wortzman, M. S., Besbris, H. J., and Cohen, A. Wertz, P. W., and Mueller, G. C. Inhibition of 12- Dowdle, E. B. Molecular Species of Plasmino- M. Effect of Dietary Selenium on the Interaction 0 - Tetradecanoylphorbol -13- acetate - acceler gen Activators Secreted by Normal and Neo- between 2-Acetylaminofluorene and Rat Liver ated Phospholipid Metabolism by 5,8,11,14-Ei- plastic Human Cells, 933 DNA in Vivo. 2670 cosatetraynoic Acid, 776 Wilson, E. L., and Dowdle, E. B. Effects of Reti- Worzalla, J. F., and Sweeney, M. J. Pyrazofurin Weselake, R. J. See Balk, Hoon. King, Loskutoff, noids on Normal and Neoplastic Human Cells Inhibition of Purine Biosynthesis via 5-Aminoim- idazole-4-carboxamide-1 -/i-o-ribofuranosyl 5'- Mitchell, LeStourgeon, and Weselake, 1753 Cultured in Vitro. 4817 West, G. W., Weichselbaum, R., and Little, J. B. Wilson, G. D., Woods, K. L., Walker, R. A., and Monophosphate Formyltransferase, 1482 Limited Penetration of Methotrexate into Human Howell, A. Effect of Prolactin on Lactalbumin Wotiz, H. H. See Muller, Sheard, Traish. and Osteosarcoma Spheroids as a Proposed Model Production by Normal and Malignant Human Wotiz, 2941 for Solid Tumor Resistance to Adjuvant Chem Breast Tissue in Organ Culture. 486 Wotring, L. L., and Roti Roti, J. L. Thioguanine- otherapy. 3665 Wilson, R. E. See Steele, Wang, Richie, Wilson. induced S and G2 Blocks and Their Significance Wheatley, W. L. See Benedict, Wheatley, and Ervin, Yankee, FallÃ³n, and Mannick, 2377 to the Mechanism of Cytotoxicity, 1458

DECEMBER1980 4867 Author Index to Volume 40

Using Xenogeneic RNA Specific to B16 Murine Yuspa, S. H. See Poirier. Santella, Weinstein, Melanoma. Cancer Res., 39. 1702-1707, Grunberger, and Yuspa, 412 Yuspa, S. H., Hawley-Nelson, P., Koehler, B., Yagawa, K., Kaku, M., Manabe, H., Yasumoto, 1979, page 1762, Letter to the Editor K., Mashiba, H., Iribe, H., Yamagata, J., Tak- Yankee, R. See Steele, Wang, Richie, Wilson, and Stanley, J. R. A Survey of Transformation enaka, K., and Nomura, Y. Superoxide Assay- Ervin, Yankee, FallÃ³n, and Mannick, 2377 Markers in Differentiating Epidermal Cell Lines Leukocyte Adherence Inhibition Test, and a Sol Yarkoni, E., and Rapp, H. J. Influence of Surfac in Culture, 4694 uble Factor which Stimulates the Adherence of tant Concentration on the Antitumor Activity of Macrophages. 4791 Emulsified Components of Mycobacteria, 975 Yager, J. D., Jr., and Yager, R. Oral Contraceptive Yasumoto, K. See Yagawa, Kaku, Manabe, Yas Steroids as Promoters of Hepatocarcinogenesis umoto. Mashiba, Iribe. Yamagata, Takenaka, in Female Sprague-Dawley Rats. 3680 and Nomura, 4791 Zachrau, R. E. See Black and Zachrau, 492 Yager, R. See Yager and Yager. 3680 Yee, G. C. See Rivera, Evans, Dahl, Yee, and Zaharko. D. S. See Chiuten, Wiernik, Zaharko, Pratt, 4250 Yagi, H. See Buening, Levin. Wood. Chang, Lehr, and Edwards, 818; Erickson, Ramonas, Za Taylor, Yagi. Jerina. and Conney, 203; Levin. Yielding, K. L. See Kulkarni, Heidepriem, and harko, and Kohn, 4216; Mirano, Ringsdorf, and Yielding, 2666 Wood, Chang, Ittah, Croisy-Delcey. Yagi. Jer Zaharko, 2263; Ramonas, Erickson, Ringsdorf, ina, and Conney, 3910; Wood. Chang, Huang. Yip, P. See Ip, Yip, and Bernardis, 374 and Zaharko, 3704; Weinstein, Magin, Cysyk, Yokota, M. See Matsukura, Kakita, Sueoka, Yosh- Levin, Lehr, Kumar, Thakker, Yagi, Jerina, and and Zaharko, 1388 Conney, 1985; Wood, Chang, Levin, Ryan, imi, Hirata. Yokota, and Fujita, 3768 Zahn, M. C. See Primus, Bennett, Kim, DeLand. Yokoyama, M. See Kitamura, Yokoyama. Mat- Thomas, Croisy-Delcey, Ittah, Yagi. Jerina, and Zahn, and Goldenberg, 497 Conney, 2876; Wood, Levin, Chang, Huang, suda, and Shimada, 3392 Zajdela, F., Croisy, A., Barbin, A., Malaveille, C., Ryan, Thomas, Lehr. Kumar, Koreeda, Akagi, Yokoyama, S. See Kaneko, Dempo, Kaku, Yokoy Tomatis, L., and Bartsch, H. Carcinogenicity of Ittah, Dansette, Yagi, Jerina, and Conney,, 642 ama, Satoh, Mori, and OnoÃ©,1658 Chloroethylene Oxide, an Ultimate Reactive Me Yalciner. S. See Pamukcu, YalÃ§iner,Hatcher, and Yonekawa, H. See Kawajiri, Yonekawa, Harada, tabolite of Vinyl Chloride, and Bis(chloro- Bryan, 3468 Noshiro, Omura, and Tagashira, 1652 methyOether after Subcutaneous Administration Yamada, S. See Okada, Yamada, Kawashima, Yoneyama, T. See Gasa, Makita, Kameya, Ko and in Initiation-Promotion Experiments in Mice, Kitade. Okajima, and Fujimoto, 1663 dama. Araki, Yoneyama. Hirama. and Hashi 352 Yamada, Y., Kawamura, T., Gotohda, E., Aki- moto, 3804 Zajdela, F. E. See Perin-Roussel, Croisy-Delcey, yama, J., Hosokawa, M., Kodama, T., and Yoo, T-J., ChiÃ¹,H. C., Spector, A. A., Whiteaker, Mispelter, Saguem, Chalvet, Ekert, Fouquet, Kobayashi. H. Effect of Normal Allogeneic Lym- R. S., Denning, G. M., and Lee, N. F. Effect of Jacquignon. Lhoste, Muel, and Zajdela, 1742 phoid Cell Transfer in Combination with Chem Fatty Acid Modifications of Cultured Hepatoma Zakour, R. A. See Tkeshelashvili, Shearman. Zak- otherapy on a Transplantable Tumor in Rats, Cells on Susceptibility to Complement-mediated our, Koplitz, and Loeb, 2455 954 Cytolysis, 1084 Zamcheck, N., and Steele, G., Jr. Concluding Yamagata, J. See Yagawa, Kaku, Manabe, Yas Yoshida, N., Kiyohara, T., Fukui, M., Atsumi, T., Remarks. 3086' umoto, Mashiba, Iribe, Yamagata, Takenaka, Ogino, S., Inaba, M., Tsukagoshi, S., and Sak- Zamora, P. O., Danielson, K. G., and Hosick, H. and Nomura. 4791 urai, Y. Antitumor Activities of Newly Synthe L. Invasion of Endothelial Cell Monolayers on Yamaguchi, K. See Kitamura, Uchida, Hayata. sized 5-Carbamoyl-1 H-imidazol-4-yl 1-Ada- Collagen Gels by Cells from Mammary Tumor Yamaguchi, Okamoto, Narita, and Matsumoto, mantanecarboxylate and 5-Carbamoyl-1 H-imi- Spheroids, 4631 4781 dazol-4-yl Piperonylate, 3810 Zander, A. See Hersh, Patt, Murphy, Dicke, Zan Yamamoto, T. See Matsuzawa. Mizuno, Yama- Yoshima, H., Mizuochi, T., Ishii, M., and Kobata, der, Adegbite, and Goldman, 3134 moto, Hori. and Suzuki, 3361 A. Structure of the Asparagine-linked Sugar Zbar, B. See Ashley, Zbar, Hunter, Rapp, and Yamamoto, Y. See Fujita, Ito, Inoue, Yamamoto, Chains of a-Fetoprotein Purified from Human Sugimoto, 4197 Takeuchi, Shamoto, and Nagatsu. 2543 Ascites Fluid, 4276 Zbar, B., Canti, G., Rapp, H. J., Ashley, M. P., Yamamoto, Y. See Tomida, Yamamoto, and Hoz- Yoshimi, H. See Matsukura, Kakita, Sueoka, Sukumar, S., and Bast, R. C., Jr. Immunopro- umi, 2919 Yoshimi, Hirata, Yokota, and Fujita, 3768 phylaxis of Syngeneic Methylcholanthrene-in Yamamoto, Y., Tomida, M., and Hozumi, M. Pro Yoshimoto, T., Inoue, T., lizuka, H., Nishikawa, duced Murine Sarcomas with Bacillus Calmette- duction by Mouse Spleen Cells of Factors Stim H., Sakatani, M., Ogura, T., Hirao, F., and GuÃªrin and Tumor Cells, 1036 ulating Differentiation of Mouse Myeloid Leu- Yamamura, Y. Differential Induction of Squa- Zech, L. See Haglund, Hayder, and Zech, 4786 kemic Cells that Differ from the Colony Stimu mous Cell Carcinomas and Adenocarcinomas in Zedeck, M. S. See Feinberg and Zedeck, 4446 lating Factor (CSF), 4804 the Lung of Mice by Intratracheal Instillation of Zenser, T. V., Mattammal, M. B., Armbrecht, H. Yamamura, Y. See Yoshimoto, Inoue. lizuka. Ni- Benzo(a)pyrene and Charcoal Powder, 4301 J., and Davis, B. B. Benzidine Binding to Nu shikawa, Sakatani, Ogura, Hirao, and Yama Young, C. W. See Arlin, Sklaroff, Gee, Kempin, cleic Acids Mediated by the Peroxidative Activ mura, 4301 Howard, Clarkson, and Young, 3304; Murgo, ity of Prostaglandin Endoperoxide Synthetase, Yamanaka, N., Kato, T., Nishida, K., Shimizu, Fried, Burchenal. Vale, Strife. Woodcock. 2839 S., Fukushima, M., and Ota, K. Increase of Young, and Clarkson, 1543; Warrell, Chou. Zenser, T. V., Mattammal, M. B., and Davis, B. Antitumor Effect of Bleomycin by Reduced Nic- Gordon, Tan, Roberts, Sternberg, Philips, and B. Metabolism of N-{4-(5-Nitro-2-furyl)-2-thia- otinamide Adenine Dinucleotide Phosphate and Young, 4546; Woodcock, Chou, Tan, Stern- zolyl]formamide by Prostaglandin Endoperoxide Microsomes in Vitro and in Vivo, 2051 berg, Philips, Young, and Burchenal, 4243 Synthetase, 114 Yamasaki, H., Saint-Vincent, L., and Martel, N. Young, N. A. See StrÃ¤uchen,Arya, Tralka, Engel, Zimmerman, A. N. E. See Breed, Zimmerman. Long-Term Effect of a Tumor Promoter, 12-0- and Young, 3880 Dormans, and Pinedo, 2033 Tetradecanoylphorbol-13-acetate, on Induced Young, P. L. See Roblin and Young, 2706 Zittoun, R. See Homo, Duval, Harousseau, Marie, Differentiation of Friend Leukemia Cells, 3780 Young, R. See Hecht, Young, and Chen, 4144 and Zittoun, 2601 Yamazaki, M. See Kurisu, Yamazaki, and Mizuno, Young, R. C. See Ozols, Willson, Grotzinger, and Zubrod, C. G. See Ganapathi, Krishan, Wodinsky, 3798 Young, 2743; Ozols, Willson, Weltz. Grotzinger. Zubrod, and Lesko. 630 Yamazoe, Y. See Ishii, Yamazoe, Kamataki, and Myers, and Young, 4109 Zucker, J-M. See LaBrosse, Com-NouguÃ©, Kato. 2596; Sugiura, Yamazoe, Kamataki, and Yu, S., Lannin, D. R., Tsui-Collins, A. L., and Zucker, Comoy, Bohuon. Lemerle, and Kato. 2910 McKhann, C. F. Effect of Cyclophosphamide on Schweisguth, 1995 Yanase, S. See Ito. Kishishita, and Yanase, 4329 Mice Bearing Methylcholanthrene-induced Fi- Zucker, S. See DiStefano, Beck, Lysik, and Yang, C. S. Research on Esophageal Cancer in brosarcomas, 2756 Zucker. 1372 China: a Review. 2633 Yuhas, J. M. Active versus Passive Absorption Zweibaum, A. See Laburthe, Rousset, Chevalier. Yang, S. K. See Wislocki, Gadek, Chou. Yang, Kinetics as the Basis for Selective Protection of Boissard, Dupont, Zweibaum, and Rosselin. and Lu, 3661 Normal Tissues by S-2-(3-Aminopropyl- 2529 Yang, S-y., Steele, G.. Jr., Wang, B. S., and aminojethylphosphorothioic Acid, 1519 Zweig, M. See Hampar, Boyd, Derge, Zweig, Mannick, J. A. Correspondence re: B. S. Wang. Yuhas, J. M. Active versus Passive Absorption Eader, and Showalter, 2213 G. Steele, Jr., J. A. Mannick. M. FallÃ³n, and S. Kinetics as the Basis for Selective Protection Zwelling, L. A. See Kleinerman, Zwelling. and R. Onikul. In Vivo Effects and Parallel in Vitro of Normal Tissues by S-2-(3-Aminopropyl- Muchmore. 3099 Cytotoxicity of Splenocytes Harvested from amino)ethylphosphorothioic Acid, 1519 Zwilling, B. S., and Davis, G. W. Effect of Bacillus Treated or Control C57BL/6J Mice after Adju Cancer Res., 40: 357-361, 1980, page 3403, Calmette-Guerin on the Development of Primary vant Immunotherapy of Pulmonary MÃ©tastases Letter to the Editor Lung Cancer in Syrian Golden Hamsters, 3455

4868 CANCER RESEARCH VOL. 40 [CANCER RESEARCH 40.4869-4929. December 1980J

Index to Volume 40

Subject Index Acetic acid, 3-methoxy-4- Adenine, 9-/3-D-arabinofuranosyl-2- hydroxyphenyl- fluoro- Neural crest neoplasms L1210 leukemia cells Acetamide, N-(acetyloxyWV-9-fT- Urinary excretion, diagnosis Deoxycytidine kinase, 3610 fluoren-2-yl- 1995 Tumorigenicity, in vivo/in vitro CRL 1121/1221/1223 fibroblast cells Neuroblastoma 3610 DNA repair, 4313 Urinary excretion, diagnosis Xeroderma pigmentosum, 4313 1995 Adenine, 9-/3-D-arabinofuranosyl, 5'- Acetamide, .V-flimriT-2-yl- Acetone, chlorohydroxy- Barbituric acid, 5-ethyl-5-phenyl- Deoxyhalo analogs monophosphate Hepatoma(s), 3268 In vitro/in vivo antitumor activi BHK 21/C13 hamster cells Tumor growth, rat, 3268 ty, 3274 Cytotoxicity, 4123 7,8-Benzoflavone Liver microsomes, hamster/rat, 354C JV-Acetoxy-2-acetylaminofluorene Carbon tetrachloride see Acetamide, JV-iacetyloxyJ-A^-W Adenine, 9-/3-D-arabinofuranosyl, 5'- In vivo carcinogenicity test, 1157 -fluoren-2-yl - triphosphate Resistant hepatocytes, 1157 2-Acetylaminofluorene Ribonucleotide reducÃase Carcinogenesis, chemical see Acetamide, JV-fluoren-2-yl- Polypeptide, liver, rat, 4688 Molt-4F lymphoblast cells, 3555 Cholanthrene, 3-methyl- A'-Acetyldaunorubicin Liver microsomes, hamster/rat, 3540 see Daunorubicin, N-acetyl- Cytochrome P-450 Catalysis, NYring-hydroxylation Acid phosphatase Adenocarcinoma(s) 4456 Neoplasm mÃ©tastases Acetone, chlorohydroxy- Dietary fat Tumor enzyme activity, mouse Deoxyhalo analogs, 3274 Carcinogenesis, liver, rat, 2802 3281 Arylsulfatases Dietary lipotropes Acridine derivatives Methanesulfon-m-anisidide, 4'-(9- Lung neoplasms, 3804 Carcinogenesis, liver, rat, 2802 Benz(a)anthracene, 7,12-dimethyI- Diethylamine, JV-nitroso- acridinylamino)- Ovary-responsive tumors, mouse Liver neoplasms, 1112 Pharmacokinetics/phase I clinical 368 Preneoplastic hepatocytes, rat, 1112 trial, child, 4250 Benz(a)anthracene, 9,10-dimethyl- DNA Leukemia(s) Methyltransferases, 417 Hepatocarcinogenesis, rat, 1269 Phase I and II clinical trials Charcoal powder DNA, nuclear 3304 Benzo(a)pyrene, 4301 Binding, hepatocytes, rat, 3579 Colonie neoplasms N-2-Fluorenylacetamide, 2802 Actin Blastogenesis inhibition factor, 29 Hepatocytes, rat Hepatocytes LS174T cells, 1443 Collagen gel-nylon mesh culture Cell culture, 4552 LSI80 cells, 1443 3259 Collagen geli/nylon mesh, 4552 Concanavalin A Protein, nuclear Actinomycin D Solid vs ascites form, rat, 1873 Binding, hepatocytes, rat, 3579 Antibodies, cytotoxic Dietary fats Selenium Differential susceptibility, cell cy Tumor growth, in vitro, mouse Binding, liver, rat, 2670 cle, 56 3745 DNA repair, 2670 5-Azacytidine DL-Glycerol DNA, single strand, 2670 Cytosine-5-methyltransferase Deoxyhalo analogs, 3274 Urea, N-methyl-AT-nitroso- 2701 Lung neoplasms Liver neoplasms, 1112 Liver, rat, in vivo/in vitro, 2701 Nucleic acid synthesis, 2295 Preneoplastic hepatocytes, rat, 1112 Lymphocytes /V,O-Acyltransferase Acetamide, N-hydroxy-N-fluoren-a-yl- Biochemical/immunological cha JV-Hydroxyarylamides Carcinogenic metabolites racteristics, 1043 JV-O-sulfate conjugation, liver, rat Substrate specificity, 834 Enzyme disaggregation, 1043 3772 Adenine, 9-/3-D-arabinofuranosyl- Isopyknic/isokinetic gradient DNA, nuclear 1043 Binding, hepatocytes, rat, 3579 BHK 21/C13 hamster cells Acetamide, iodo- Cytotoxicity, 4123 Mammary neoplasms CCRF-CEM cells Benz(a)anthracene, 7,12-dimethyl- DNA methylase Guanidine, N-methyl-W-nitro-JV- Cytotoxicity, 1405 368 nitroso-, 61 DNA synthesis, 1405 Glycoproteins, 1873 Cytidine, deoxy- Acetamide, thio- Histological/ultrastructural study, Cytotoxicity, 1405 mouse, 1588 RNA DNA synthesis, 1405 Liver nuclei, rat, 75 Hormone stimulation, mouse Deoxycoformycin Nucleoside triphosphatase, 75 368 CCRF-CEM lymphoblastoid cells Immune response, rat, 3484 Acetazolamide 2349 Neoplasm metastasis, 1588 Methotrexate DNA synthesis, 2349 Solid vs ascites form, rat, 1873 Cerebrospinal fluid levels, human Leukemia, lymphoblastic Virus, murine mammary tumor 2184 DNA synthesis, 1405 368

DECEMBER 1980 4869 Subject Index to Volume 40

Adenocarcinoma(s) (cont'd) Adenosine cyclic 3':5'-monophosphate Adenosine S'-triphosphatase (cont'd) Norepinephrine RL34 cells Antitumor activity, 4320 Secretin, 2529 Cell transformation, neoplastic Pancreatic neoplasms Vasoactive intestinal peptide 1318 Dipropylamine, 2,2'-dioxo-N- 2529 S-Adenosylmethionine decarboxylase nitroso-, 67 Gonadotropins, chorionic Estrogen TPA30-1 transformed placenta! Morpholine, 2,6-dimethyl-N- Sex factors, liver, rat, 620 nitroso-, 67 cells, 4025 Formamide, JV-[4-(5-nitro-2-furyl)-2- Peanut agglutinin Choriocarcinoma, 4025 thiazolyl]- Guanosine cyclic 3':5'- Sialoglycoprotein, 1873 Enzyme activity, mouse, 1897 Solid vs ascites form, rat, 1873 monophosphate Guanidine, l,-l '-(methylethanedi- Prostatic neoplasms Urine/plasma, cancer patients/ ylidenedinitriloldi- Receptors, hormone, 2188 normals, 3915 Tamoxifen, 2188 Isoproterenol Intestinal mucosa, rat, 2330 Proteinases Granulocyte-macrophage colony- L1210 leukemia cells Breast neoplasms, 550 forming units, 1223 Guanidine, l.-l ' -(methylethanedi- RNA, transfer Methotrexate ylidenedinitrilo)di- Methyltransferases, 417 Membrane transport, 2400 Testosterone SKCO-1 cells Neuroblastoma Sex factors, liver, rat, 620 Blastogenesis inhibition factor, 29 Proteins, 2884 Thiazole, 2-amino-4-(5-nitro-2-furyl)- Stomach neoplasms Phosphodiesterase Antigens, neoplasm, 897 Blastogenesis, lymphocytes, hu Enzyme activity, mouse, 1897 Glycolipids, 897 man, 379 Surface-active agents P388D, cells, 1955 S-Adenosylmethionine synthetase Growth inhibition, in vivo vs in Enzyme activity, human, 1955 Enzyme pattern, liver, fetal/ vitro, 1173 Monocytes, 1955 postnatal rat, 2895 Vasoactive intestinal peptide Prostaglandin E, Adenosine cyclic 3':5'- Granulocyte-macrophage colony- Adenyl cyclase monophosphate, 2529 forming units, 1223 Adrenal cortex neoplasms Prostaglandin F2a Enzyme activity, normal/ Granulocyte-macrophage colony- Adenofibroma hyperplastic/neoplastic glands, see Fibroadenoma forming units, 1223 human, 3768 Protein kinases Receptors, hormone, 3768 Lymphocytes, normal/neoplastic Calcitonin Adenoma(s) 2714 BEN cells, 1311 Oral contraceptives Proteins Human breast cancer cells Hepatocarcinogenesis, rat, 3680 Cell membrane, 2860 Human breast epithelial cells Virus, lÃ¡clate dehydrogenase Cell transformation, neoplastic 4764 Carbamic acid, ethyl ester, 64 2860 Immune response, mouse, 64 12-O-Tetradecanoylphorbol-13- Adenylate kinase acetate Nucleic acid synthesis Epidermal cells, mouse, 2653 Lung neoplasms, 2295 Adenosine Vindesine B16 melanoma cells L1210 cells, 2695 Cytostasis, neoplastic vs normal Adenylosuccinate synthetase Adenosine cyclic 3':5'-monophosphate, L-Alanosine cells, mouse, 2147 N% O2'-dibutyryl- Ribonucleotide, 5-amino-4- Adenosine cyclic 3':5'-monophosphate HL-60 cells imidazole carboxylic acid Adenylyl cyclase 4390 Colony formation, 1858 Blastogenesis, lymphocytes, hu KG-1 cells Adenylyl cyclase man, 379 Adenosine cyclic 3':5'- Butyric acid Colony formation, 1858 monophosphate Isoproterenol, 240 Adenosine deaminase Blastogenesis, lymphocytes, hu Carbamylcholine Adenine, 9-/3-D-arabinofuranosyl- man, 379 Granulocyte-macrophage colony- CCRF-CEM lymphoblastoid cells Guanosine cyclic 3':5'- forming units, 1223 2349 monophosphate Carcinoma, Ehrlich tumor Adenine, 9-/8-D-arabinofuranosyl-2- Blastogenesis, lymphocytes, hu Methotrexate, 2400 fluoro- man, 379 HL-60 cells CCRF-CEM lymphoblastoid cells Colony formation, 1858 2349 Adrenal gland neoplasms K.G-1 cells Adenyl cyclase Colony formation, 1858 Adenosine kinase Enzyme activity, normal/ N-18 mouse neuroblastoma cells Adenine, 9-/3-D-arabinofuranosyl- hyperplastic/neoplastic glands, Binding protein, 4100 BHK 21/C13 hamster cells, 4123 human, 3768 Adenine, 9-ÃŸ-D-arabinofuranosyl, 5'- Colonie neoplasms Receptors, hormone, 3768 Isoproterenol, 2529 monophosphate Ovariectomy Prostaglandins E, 2529 BHK 21/C13 hamster cells, 4123 Spontaneous tumors, aged mouse

4870 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Adrenal gland neoplasms (cont'd) Adriamycin, JVJV-dimethyl- Alcohol dehydrogenase Spontaneous tumors, aged mouse P388 cells Methanol, (methyl-CWN-azoxy)- 3570 Pharmacokinetics, mouse, 1928 Carcinogenic metabolite, 4446 Virus, type C, 3570 Sodium azide Pharmacokinetics, mouse, 1928 Alkaline phosphatase Adrenalectomy Placenta Receptors, hormone Adriamycinol Antibody binding, normal/ Mammary neoplasms, 1612 Cirrhosis neoplastic tissue, human, 4064 Plasma drug levels, 1263 Horseradish peroxidase, 4064 Adrenaline Hepatoma(s) Testes see Epinephrine Plasma drug levels, 1263 D-Variant enzyme, placental-type Adriamycin Transaminase, 1263 1506 Developmental gene expression Albumin microspheres Aflatoxin B, Fibrosarcoma assay, 3512 V-79 Chinese hamster cells 1506 Release rate, 3512 Mutagenesis, 1836 Alkylating agents Anemia Dietary fat C3H/1OT1/2 cells Bone marrow/spleen, mouse Carcinogenesis, liver, rat, 2802 Cytotoxicity, 682 2257 Dietary lipotropes Erythropoiesis, 2257 DNA synthesis, 682 Carcinogenesis, liver, rat, 2802 Mutagenesis, 682 Cardiac mammalian cells Dimethylamine, JV-nitroso- Chinese hamster V79 cells Cardiac toxicity, 4133 Synergistic Carcinogenesis,rat Cytotoxicity, 682 CHO cells 4037 DNA synthesis, 682 Cytotoxicity vs cell cycle, 3437 DNA Mutagenesis, 682 P388 cells Adduci formation vs colony-cell Misonidazole Pharmacokinetics, mouse, 1928 viability, 2904 Neoplasms, mouse, 4165 Cirrhosis 10T1/2 mouse embryo cells Synergistic activity, 4165 Plasma drug levels, 1263 2904 Daunorubicin Allopurinol DNA synthesis Cardiotoxicity, mechanism, 4581 see //-Pyrazolo(3,4-d)pyrimidin-4-ol C3H/10T1/2 CL8 mouse fibrob- Intestinal mucosa cells, human a-Amanitin last cells, 4581 3155 Photoactivation, 689 Virus, type C Hepatoma, Novikoff Template activity, 689 Viral activation, 22 Antitumor activity, 387 Hepatocarcinogenesis, rat Hepatoma(s) DNA-adduct formation, 4085 Ames test Pharmacokinetics, human, 1263 Arylhydroxamic acid acyltransferase Hepatoma(s) Plasma drug levels, 1263 Hydroxylamines, N-acyl-N-2- Hepatectomized rat, 4739 Leukemia L1210 fluorenyl-, 1204 Histones Antitumor activity, 387 Benz(a)anthracene, 7,12-dimethyl- Liver, rat, in vivo, 4343 Circadian bioperiodic response, 3,4-Dihydrodiol derivatives, 3661 Mammary cells mouse, 1511 Hydroxymethyl derivatives, 3661 Metabolic activation, 1836 Liposomes Benzo(e)pyrene Carcinoma, Lewis lung, 1532 Aflatoxins Diol-epoxides/tetrahydroepoxides Cardiotoxicity, mouse, 1532 Chemiluminescence 1985 P388 leukemia cells, 1532 Carcinogenic metabolites, 2002 Triphenylene, 1985 Drug entrapment, 1532 DNA repair Breast fluid Positive/negative charge, 1532 Age, sex, diet factors, rat, 3719 Letter to the editor, 188 Mammary neoplasms Butyric acid, 4-(N-butyl-7V- Cell kinetic recovery, rat, 737 Aging nitrosamine)- Virus, murine leukemia Mastocytoma RNA-complementary DNA hy Bladder neoplasms, 162 Cytotoxic immune response, in Carcinogenic metabolites, 162 bridization analysis, 519 vitro, 2748 Butyric acid lactone, 4-(N- Ovarian neoplasms AH 130 tumor butylnitrosamino)-4-hydroxy- Cell culture, 2743 Aminotransferases Bladder neoplasms, 162 Cytotoxicity in vitro vs in vivo, Thymus involution, rat, 877 Carcinogenic metabolites, 162 human, 4109 Alanine, 3-(3,4-dihydroxyphenyD-, I - Carbamic acid, ethyl ester Liver system, rat/duck, 1194 Metabolites, 4109 DNA synthesis Ricin Carbamic acid, hydroxy-, ethyl ester Antineoplastic analogs, human/ L1210 leukemia cells, 3735 Liver system, rat/duck, 1194 mouse cells, 1414 Cytotoxicity/synergistic drug ac Carbamic acid, vinyl ester Melanoma(s), 1414 tion, 3735 Liver system, rat/duck, 1194 Sodium azide Tyrosinase Cytochrome P-450 DNA polymerase, 1414 Pharmacokinetics, mouse, 1928 Metabolic activation, 1652 a-Tocopherol Alanosine, I - Deacylase Cardiac toxicity, rabbit, 1022 Ribonucleotide, 5-amino-4-imidazole Hydroxylamines, N-acyl-N-2- film alinone, 1022 carboxylic acid fluorenyl-, 1204 Dipropylamine, 2,2'-dihydroxy-N- Transaminase, 1263 Adduci formation, 4390 Vitamin E Adenylosuccinate synthetase nitroso- Cardiotoxicity, rabbit, 2033 4390 V79 hamster liver cells, 3463

DECEMBER 1980 4871 Subject Index to Volume 40

Ames test (cont'd) S-2-O-Aminopropylamino)ethylphos- 9,10 Anthracenedione. l,4-bisÂ«2-<[2- Dipropylamine, 2,2'-dioxo-N-nitroso- phorothioic acid hvdroxyethyl)amino]ethvl)amino)-. Carcinogenic metabolites, hamster see Phosphorothioic acid, S-2-(3- diacetate 67 aminopropylamino)ethyl- Antineoplastic agents Pharmacokinetics, dog, 1427 V79 hamster liver cells, 3463 Aminotransferases Ethylene, chloro- Hydrocortisone Liver microsomes, human/rat AH 130 tumors, rat, 877 9,10-Anthracenedione, 1,4-dihydroxy- 119 Thymus involution, rat, 877 5,8-bistt(2- [(2-hyd rox yethyDamino] - Fatty acids, polyunsaturated ethyDamino))-, dihydrochloride Amphotericin B Mutagenic metabolites, 276 Antineoplastic agents Hypolipidemic peroxisome prolifera- C3H IOTI/2 cells Phase I clinical trial, 1516 Malignancy vs heat/antibiotic tors sensitivity, 3763 Anthracenes, halomethyl DNA synthesis, 36 Daunomycin Morpholine, 2,6-dimethyl-N-nitroso- Alkylation, in vitro Antitumor activity, mouse, 1351 Carcinogenic metabolites, hamster Carcinogenicity, mouse, in vivo Drug entrapment, 1351 782 67 Urea, 1-(2-chloroethyl)-3-cyclohexyl- Morpholine, N-nitroso- DNA 1-nitroso- Carcinogenicity, mouse, in vivo Liver microsomes, human/rat Antitumor activity potentiation, 782 119 mouse, 939 Lung neoplasms Piperazine, AT-methyl-N-nitroso- Androgen Carcinogenicity, mouse, in vivo Liver microsomes, human/rat SCI 15 mouse mammary carcinoma 782 119 cells Solvolysis, in vitro Propanedial Serial passage, mouse, 4781 Carcinogenicity, mouse, in vivo Mutagenic metabolites, 276 Prostatic neoplasms 782 Propylamine, 2-hydroxymethyl-AT- Hormone dependency, rat, 3551 nitroso- Receptors, hormone V79 hamster liver cells, 3463 Anthracycline antibiotics Breast neoplasms, 2557 Cardiotoxicity/pharmacokinetics Sulfotransferase Hydroxylamines, JV-acyl-N-2- Androst-5-ene-3/3,17/3-diol Chronic studies, rabbit, 3530 C3H/10T1/2 CL8 mouse fibroblast fluorenyl-, 1204 Dehydroepiandrosterone Radioimmunoassay, human breast cells Amino acids cytosol, 3815 Cardiotoxicity, mechanism, 4581 Benzaldehyde L1210 leukemia cells Anemia Drug uptake, 4669 Metabolism, transformed fibrob- Adriamycin lasts, 2574 Nuclear cytoplasm, 4669 Bone marrow/spleen, mouse DNA synthesis Phenylalanine, L-p-(di-2- 2257 chloroethylamino)- Cell viability, 387 Erythropoiesis, 2257 DNA-binding characteristics, 387 DNA cross-linking, 1169 Anemia-inducing factor Intracellular fluorescence 3-Amino-l,4-dimethyl-5H-pyrido(4,3-W- Neoplasm diagnosis, 1686 Laser flow cytometry, 3895 Cytosine, l-/3-D-arabinofuranosyl- indole Nogalamycin see 5fi-Pyrido(4,3-b)indole, 3-amino- Bone marrow/spleen, mouse Analogs, 3437 2257 1^-dimethyl Cytotoxicity vs cell cycle, 3437 Erythropoiesis, 2257 s'Amino-l-methyl-5H-pyrido(4,3-ft)in- Aneuploidy Anthralin dole Leukemia, acute nonlymphocytic Saccharomyces cerevisiae see 5//-Pyrido(4,3-ft)indole, 3-amino- Growth kinetics, human marrow Mitotic recombination/ 1-methyl- cells, 1292 mutagenicity, 2323 Syrian hamster embryo cells l-(4-Amino-2-methyl-5-pyrimidinyl)- Ultraviolet rays Transformation, neoplastic, 91 methyl-3-(2-chloroethyl)-3-nitrosourea Mitotic recombination/ hydrochloride Angelicin mutagenicity, 2323 see Urea hydrochloride, l-(4-amino-2- DNA repair methyl-5-pyrimidinyl)methyl-3-(2- Photoactivation, 696 Anthraquinone, 1,8-hydroxy- chloroethyl)-3-nitroso- WI-38 fibroblast cells, 696 Antineoplastic agents Xeroderma pigmentosum cells Cell cycle kinetics, 42 DL-/3-2-Aminobicyclo[2,2,l]heptane-2- 696 Chinese hamster ovary cells, 42 carboxylic acid X-rays Angiosarcoma see 2-Carboxylic acid, DL-/3-2- Cell cycle kinetics, 42 aminobicyclo[2,2,l]heptane- Nitrosamines Carcinogenicity, guinea pig, 1879 S-Aminoimidazole-'J-carboxamide-l-/?^- Antibodies Ansamitocins ribofuranosyl, 5 -monophos- Hybrid cells Antibiotics Cytotoxicity, lymphocytes virus- phate Antitubulin activity, bovine brain producing, 3850 see Imidazole-4-carboxamide-l-/3-D- 1707 ribofuranosyl, 5-amino-, 5 -mono- Antitumor activity, mouse in vivo Antibodies, antiidiotypic Freund's adjuvant phosphate 1707

4872 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Antibodies, antiidiotypic (cont'd) Antiestrogens Antigens, neoplasm (cont'd) Immune response, mouse, 1630 170-Estradiol Serotherapy, case report, 3147 IgA Breast neoplasms, 1722 Melanoma(s) MOPC 315 myeloma cells, 1630 DNA polymerase, 1722 Hybridoma(s), 2523 Immune response, mouse, 1630 Receptors, hormone Placenta Hormonal control, breast cancer Alkaline phosphatase, 4064 Antibodies, antireceptor 1750 Polyribosomes Receptors, hormone Uterus, guinea pig, 3821 Neoplastic/normal/regenerating Estrogens, 3172 Antigen, nonspecific cross-reacting liver, rat, 1367 Isolation and characterization Nucleolar proteins, 1367 Leukemia, acute nonlymphoblastic 3172 Prostatic neoplasms Diagnosis, 2039 Antibodies, cytotoxic Serum/bone marrow cells, nor- Diagnostic marker, 2428, 4658 Identification and characteriza Actinomycin D mal/neoplastic, 2039 tion, sera, patients, 2428 Differential susceptibility, cell cy Leukemia, chronic myelocytic cle, 56 Sarcoma(s) Diagnosis, 2039 Cross-protection, mouse/hamster Melphalan Serum/bone marrow cells, nor- 1568 Differential susceptibility, cell cy mal/neoplastic, 2039 cle, 56 Isolation and characterization S107 myeloma cells T-Antigen 4204 Differential susceptibility, cell cy Peanut agglutinin Stomach neoplasms cle, 56 Sialoglycoprotein, 1873 Adenocarcinoma(s), 897 Suppressor cells Antigens, fetal Antibodies, monoclonal Immune response, rat, 2129 Antigens, neoplasm Colonie neoplasms Virus, feline leukemia Cross-protection, hamster, 1380 Tumor-growth inhibition, mouse Antibodies, neoplasm, 3642 Cross-protection, mouse/hamster 717 Virus, murine leukemia 1568 Cross-protection, mouse, 1036 Antibodies, neoplasm Fibroblasts Virus, SV40 Cervix neoplasms Complement-dependent cytotoxic Cell transformation, viral, 1380 Virus, herpes simplex 1, 4640 reactivity, sera, human, 979 Virus, herpes simplex 2, 4640 Sarcoma(s) Antigens, nucleolar Hybridoma(s) Complement-dependent cytotoxic HeLa S3 cells Binding, cultured/freshly isolated reactivity, sera, human, 979 Identification and purification neoplastic cells, 3602 Virus, SV40 3194 Melanoma(s) Cell transformation, viral, 1380 Namalwa cells Hybridoma(s), 2523 Identification and purification Antigens, neoplasm Virus, feline leukemia 3194 Antigens, neoplasm, 3642 Antigens, fetal Cross-protection, hamster, 1380 Isolation and characterization Cross-protection, mouse/hamster Antigens, preneoplastic 3642 1568 Isolation and characterization Antibodies, viral BALB/c lung carcinoma cells Hyperplastic liver, rat, 3755 Cell transformation, viral Identification and characterization Virus, herpes simplex 2, 2074 2153 Antigens, surface Cervix neoplasms HeLa S3 cells Immune serums Virus, herpes simplex 1, 4640 Identification and purification Indirect rosette microassay, 2252 Virus, herpes simplex 2, 4640 3194 Virus, SV40 Viral proteins Namalwa cells Cell transformation, viral, 1380 Microcytotoxicity assay, human Identification and purification fluids, 166 3194 Antigens, viral Radioimmunoprecipitation, 166 Colonie neoplasms Cell transformation, viral Virus, herpes simplex 2 Tumor-growth inhibition, mouse Virus, herpes simplex 2, 2074 Serum, rat, 2074 717 REI cells Virus, type C Glycolipids Virus, herpes simplex 2, 2074 Microcytotoxicity assay, human Immunotherapy, 897 Fusobacterium nucleatum fluids, 166 Mass spectrometry, human, 897 P3HR-1 human lymphoblastoid Radioimmunoprecipitation, 166 Hepatoma(s) cells, 4329 Bacillus Calmette-Guerin, 4197 Mammary neoplasms Antibody specificity Complement-dependent cytotox- DNA, proviral, 2316 Me-43 melanoma cells icity, tumor-bearer sera, rat DNA-RNA hybridization, 2316 P3-NSI/lAg4 melanoma cells 1691 MÃ©tastases, 2316 2523 Xeroderma pigmentosum Cytochrome P-450 Immune serums Indirect rosette microassay, 2252 Virus, adeno type 2, 3945 Liver microsomes, 1652 Leukemia, myeloblastic Antibody targeting Lymphocyte typing test, 3218 Antineoplastic agents Diphtheria toxin T-Lymphocytes, 3218 Acetone, chlorohydroxy- Tumor-specific chemotherapeutic Lymphoma(s) In vitro/in vivo antitumor activity agents, 3564 Immune serums, 3147 3274

DECEMBER 1980 4873 Subject Index to Volume 40

Antineoplastic agents (cont'd) Antineoplastic agents (cont'd) Antineoplastic agents (cont'd) 4'-(9-Acridinylamino)methanesulfon-m Chronic studies, rabbit, 3530 Mitomycin C -anisidide Cesalin LoVo cells, 1973 Leukemia(s), 3304 Cytotoxicity assay, mammalian Colonie neoplasms, 1973 Phase I and II clinical trials cells, 225 Neocarzinostatin 3304 Cyclophosphamide HeLa S, cells, 2405 Adenine, 9-/3-D-arabinofuranosyl- Drug sensitivity assay, 4443 DNA repair, 2405 CCRF-CEM lymphoblastoid cells Hydrolysis vs antitumor activity, Nogalamycin 2349 mouse, 2263 Analogs, 3437 DNA synthesis, 2349 Neoplasm growth, 2179 Cytotoxicity vs cell cycle, 3437 Sensitive/resistant cells, 1405 Sulfhydryl derivatives, 3704 Ovarian neoplasms Adenine, 9-/J-D-arabinofuranosyl-2- Sulfido derivatives, 4216 Malignant effusion/abdominal fluoro- Toxicity, mouse, 2263 washings, human, 2743 CCRF-CEM lymphoblastoid cells Tumorigenicity/toxicity, mouse Pentamethylmelamine 2349 3704 Pharmacokinetics, mouse, 2762 DNA synthesis, 2349 Cytolysis Phenylalanine, 5-S-cysteinyl-L-3,4- Sensitive/resistant cells, 1405 Macrophages vs cancer cells dihydroxy- Adriamycin 1372 Antitumor activity, in vitro Ricin, 3735 Cytosine, l-/3-arabinofuranosyl- 2543 L-Alanosine Metastases, 4758 L-Phenylalanine mustard Adduci formation, 4390 Daunorubicin Gas chromatography-mass spec- Ansamitocins Leukemia, AKR, 2835 trometry assay, 2268 Antitubulin activity, bovine brain 3-Deazauridine Af-iPhosphonacetyO-L-aspartate 1707 5-Azacytidine, 4000 Phase I clinical trial, 2938 Antitumor activity, mouse in vivo Phosphoramide mustard Doxorubicin 1707 Adduci formation, 4138 9,10-Anthracenedione, 1,4-bis((2-([2- Derivatives, 4682 Guanosine, 4138 hydroxyethyl)amino]elhyl)amino)- Drug therapy Phosphorodiamidic acid,JV,AT-di-(2- diacetate Human solid tumor cells, 4438 chloroethyl)- Pharmacokinetics, dog, 1427 Drug sensitivity assay, 4438 Plasma levels, human, 4734 9,10-Anthracenedione, 1,4-dihy- D-Glucopyranose, 2-(3-(2- Platinum(II)chloroammines droxy-5,8-bis(((2-[(2-hydroxy- chloroethyl)-3-nitrosoureido)- Chinese hamster ovary cells ethyDamino]-ethyl lamino))-, L15178Y lymphoblast cells, 3950 1463 dihydrochloride Hematological toxicity, mouse Platinum(II), diamminedichloro-, cis Phase I clinical trial, 1516 4282 DNA, PM-2, 3313, 3318 Anthracylic antibiotics Acinetobacter glutaminase- Second-generation platinum ana Cardiotoxicity, mechanism, 4581 asparaginase logs, 3318 Anthraquinone, 1,8-hydroxy- Phase I clinical trial, 4546 2-Propanol, l-(2-nitro-l-imidazolyl)- Cell cycle kinetics, 42 3-methoxy- Chinese hamster ovary cells, 42 DL-Glycerol Mechanism of action, 2165 Asparaginase In vitro/in vivo antitumor activi Pseudoisocytidine ty, 3274 Immunosuppression, 1125 Guanidine, 1,-1' -(methylethanedi- Biochemical/pharmacological ac Aspartate, N-(phosphonacetyl)- tivity, 4243 ylidenedinitrilo)di- Cerebrospinal fluid levels, human Phase I clinical study, 4243 patients, 3163 Mitochondrial damage, mouse, in Pyrazofurin, 1482 Aspartic acid, JV-(phosphonacetyl)- vivo, 4533 Receptors, hormone Aspartate carbamoyltransferase Toxicity, rat, 2330 Breast neoplasms, 2941 86 Hexamethylmelamine Estrogen, 2941 Pharmacokinetics, 86 Pharmacokinetics, mouse, 2762 Uterus, rat, in vitro, 2941 Bleomycin L-Canavanine Retinoic acid Drug sensitivity assay, 4443 Antitumor activity, mouse, 535 3T3 cells, 3089 C3H fibroblast cells Retinoids Agent screening assay, 943 Leukemia LI210 Trachea, hamster, 3413 Cell proliferation vs invasiveness Cell proliferation, 2695 Theophylline 943 Melamine, hexamethyl- Urea, l,3-bis(2-chloroethyl)-l- Directional migration, 943 L5178Y lymphoblast cells, 4489 nitroso-, 2202 Caffeine Drug uptake, 4489 Thymidine Carbamic acid, ethyl ester, 1332 Methanesulfon-m-anisidide, 4'-(9- Pharmacokinetics, clinical study, phase 1-2, 818 DNA repair, 1332 acridinylamino)- Quinoline, 4-nitro-, 1-oxide, 1332 Uracil, 5-fluoro- 5-Carbamoyl-l//-imidazol-4yl 1- Pharmacokinetics/phase I clinical Dose-response culture, 3202 trial, child, 4250 adamatanecarboxylate Lipophilic derivative, 4758 Antitumor activity, mouse, 3810 Methotrexate Mammary neoplasms, 2730 5-Carbamoyl-1//-imidazol-4yl pipero- Dose-response culture, 3202 Pharmacokinetics, 107 nylate Drug uptake, 4768 Testosterone, 2730 Antitumor activity, mouse, 3810 Misonidazole Thymidine, 107 Cardiotoxicity/pharmacokinetics Alkylating agents, 4165 Uracil, R,S-1-(tetrahydro-2-furanyl)-

4874 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Antineoplastic agents (cont'd) l-/i-D-Arabinofuranosylc> tosine Ascorbic acid V-Butyrolactone, 2814 see Cytosine, 1-/3-D- Cell transformation, neoplastic Metabolites, in vivo/in vitro arabinofuranosyl- C3H/10T1/2 mouse embryo cells 2814 l-/3-D-Arabinofuranosylcytosine 5'- 2796 Uracil, 5-fluoro-, 2814 Glutathione Urea, 3-[(4-amino-2-methyl-5- triphosphate Bone marrow cells, human, in vitro see Cytosine, 1-/3-D- pyrimidinyl)methyl]-l-(2-chloro- arabinofuranosyl, 5'- 'Leukemia,1062nonlymphocytic ethyO-nitroso- triphosphate Transplantation, heterologous Bone marrow cells, human, in vitro 133 Arginine 1062 Ultrastructural study, nucleolus, Fibronectin Asparaginase mouse, 133 Cell transformation, neoplastic Escherichia coli Urea, (chloro-2-ethyl)-l- 2562 Glutaminase, 1125 ribofuranosyl-3-nÃtroso- Aroclor 1254-induced rat liver Plaque-forming cell assay, 1125 Hematological toxicity, mouse Benz(a)anthracene, 7,12-dimethyl- Vibrio succinogenes 4282 Carcinogenic metabolites, in vivo Plaque-forming cell assay, 1125 Urea, 1-(2-chloroethyl)-3-(2,6-dioxo- vs in vitro, 655 Aspartate 3-piperidyl)-1-nitroso- DNA adducts, 655 Glutamate Phase I clinical trial, 3750 Urea, l-(2-chloroethyl)-3-(l'-(5'-p- Arsenic Normal/neoplastic tissue, rat nitrobenzoyl-2',3'-isopropylidene DNA synthesis 4053 Aspartate, N-(phosphonacetyl)- o,/3-D-ribofuranosyl)-l-nitro.so- DNA polymerase, 2455 Pharmacokinetics, mouse/rat Aryl hydrocarbon hydroxylase Antineoplastic agents L-Aspartate carbamoyltransferase 3351 Benz(a)anthracene Undine, 5-deoxy-5-fluoro- Carcinogenic metabolites, 424 86 Pharmacokinetics, 86 Antineoplastic activity, in vivo/in Benzo(a)pyrene Aspartate transcarbamylase vitro, 3333 Enzyme inducibility, 1305 Competitive protein-binding assay Vincristine 7,8-Benzoflavone 1-Propargyl-S-chlororpyrimidin^- 1902 Enzyme inhibition, fetal cells, Pharmacokinetics, human, 1902 one, 2069 mouse, 424 X-rays Cholanthrene, 3-methyl- Central nervous system neoplasms Cerebrospinal fluid levels, human Cell survival assay, mouse, 145 Carcinogenic metabolites, 424 patients, 3163 Growth inhibition, 145 Genetic regulation, fetal cells, mouse ara-A In vivo vs in vitro function, 424 Aspartate transcarbamylase see Adenine, 9-/3-D- Hormone regulation Antineoplastic agents arabinofuranosyl- Testis, hypophysectomized rat Aspartic acid, N-(phos- 2486 phonacetyl)-, 86 L-Aspartic acid, 7V-(phos- ara-C Arylamide JV-hydroxylase phonacetyl)- see Cytosine, 1-/3-D- 7,8-Benzoflavone Competitive protein-binding assay arabinofuranosyl- Liver microsomes, hamster/rat 1902 3540 Pharmacokinetics, human, 1902 ara-CTP Cholanthrene, 3-methyl- see Cytosine, 1-/3-D- Liver microsomes, hamster/rat Astrocytoma(s) arabinofuranosyl, 5'- 3540 Antibodies, neoplasm triphosphate Binding, cultured/freshly isolated Arylamine \-hydroxylasc neoplastic cells, 3602 7,8-Benzoflavone F-ara-A Polyamines Liver microsomes, hamster/rat see Adenine, 9-/3-D- Cerebrospinal fluid, human, 3293 arabinofuranosyl-2-fluoro- 3540 Weibel-Palade bodies Cholanthrene, 3-methyl- Diagnosis, 2010 9-/3-D-Arabinofuranosyl-2-fluoro- Liver microsomes, hamster/rat 3540 Ataxia telangiectasia see Adenine, 9-/3-D- DNA repair arabinofuranosyl-2-fluoro- Arylhydroxamic acid acyltransferase Guanidine, N-methyl-AT-nitro-N- Hydroxylamines, JV-acyl-N-2- nitroso-, 984 9-/3-D-Arabinofuranosyladenine fluorenyl- ace Adenine, 9-/3-D-arabinofuranosyl- Methanesulfonic acid, methyl es Ames test, 1204 ter, 984 Enzyme activity, liver, rat, 1204 9-/3-D-Arabinofuranosyladenine 5 â€¢mono- Ultraviolet rays, 984 phosphate Ary (sulfatases Autoantigens see Adenine, 9-/3-D-arabinofuranosyl-. Lung neoplasms Hepatoma(s) 5 -monophosphate Adenocarcinoma(s), 3804 Complement-dependent cytotox- Carcinoma, epidermoid, 3804 icity, tumor-bearer sera, rat 9-/3-D-Arabinofuranosyladenine 5 -triphos- 1691 phate Ascitic Huid see Adenine, 9-/3-D-arabinofuranosyl-, Cell differentiation Autochthonous tumors 5'-triphosphate Ml myeloid leukemia cells, 3387 X-rays

DECEMBER 1980 4875 Subject Index to Volume 40

Autochthonous tumors (cont'd) Bacillus Calmette-Guerin (cont'd) Benz(a)anthracene (cont'd) Radioresistance, mouse, 2547 Hamster, Syrian golden, 3455 Carcinogenic metabolites, 424 Sorbitan monooleate, polyoxyethy- Autophagocytosis lene derivative Guanidine Antitumor activity, 975 Benz(a)anthracene, 7,12-dimethyl- Ultrastructural study, 1054 Emulsified components, 975 Adenocarcinoma(s) 5-Azacytidine Suppressor cells Ovary-responsive tumors, mouse Cytidine, 5-methyl- Bone marrow/spleen, mouse, 80 368 Liver, rat, in vivo/in vitro, 2701 Macrophage-granulocyte colony- Aroclor 1254-induced rat liver Cytosine-5-methyltransferase forming cells, 80 Carcinogenic metabolites, in vivo Liver, rat, in vivo/in vitro, 2701 vs in vitro, 655 Bacillus subtilis RNA, transfer, 2701 DNA adducts, 655 Purine-6-thiol V-79 Chinese hamster cells Azaserine DNA, 4381 Mutagenesis, 1836 6-Thioguanine see Serine, diazoacetate (ester) Chemiluminescence DNA, 4381 Azimexon Carcinogenic metabolites, 2002 Carcinoma M109 Bacteriophage l'M-2 Chromosome aberrations Lymphoma(s), 2609 Mouse, in vivo, 1967 Bleomycin Thymectomized/intact/Freund's Leukemia L1210 DNA, single-strand, 4173 Mouse, in vivo, 1967 Talisomycin adjuvant-fed mouse, 2609 Leukemia LSTRA DNA, single-strand, 4173 Cyanic acid, sodium salt Chemical carcinogenesis inhibitor, Mouse, in vivo, 1967 Barbituric acid, 5-ethyl-5-phenyl- rat/mouse, 232 Azobenzene, 7V-benzoyloxy-JV-methyl-4- Acetamide, JV-fluoren-2-yl- Dietary fat amino- Hepatoma(s), 3268 Carcinogenesis, mouse, 2785 DNA Tumor growth, rat, 3268 Mammary neoplasms, 2785 Adduci formation, in vitro, 2493 T51B rat liver cells 3,4-Dihydrodiol derivatives Azobenzene, \. V-dirncth) l-4-Ãiminn- Calcium, 4541 Carcinogenicity/mutagenicity DNA synthesis, 4541 DNA 3661 Choline Adduct formation, in vitro, 2493 Hydroxymethyl derivatives Hepatocarcinogenesis, rat, 3846 Carcinogenicity/mutagenicity Azobenzene, 3'-methyl-4- Cytochrome P-450 3661 dimethylamino- Precancerous conditions, liver, rat Mammary cells Carcinogenesis, chemical 1658 Metabolic activation, 1836 Polypeptide, liver, rat, 4688 Diethylamine, JV-nitroso- Organ-specific carcinogenesis Azobenzene, N-methyl- Hepatocarcinogenesis, rat, 4261 1836 Epoxide hydrolase Mammary neoplasms DNA Lymphocytes, fresh/mitogen- Adduct formation, in vitro, 2493 Adenocarcinoma(s), 368 stimulated, 2552 Estrogen, 2343 Azoprocarbazine Liver microsomes Hormonal control, 1612 see p-Toluamide, JV-isopropyl-a-(2- Enzyme activity, 1658 Hormonal stimulation, mouse methylazo)- Precancerous conditions, liver, rat 374 1658 Azoxymethane p-Toluamide, JV-isopropyl-a-(2- Hypothyroidism, 2336 see Methane, azoxy- Insulin, 2343 methylazo)- Receptors, hormone, 2343 Bacillus Calmette-Guerin Liver microsomes, rat/rabbit Retinoic acid, 47 Carcinoma M109 3524 Retinyl acetate, 1140 Mouse, in vivo, 1967 Metabolites, 3524 RNA, messenger, 362 Line 10 hepatocarcinoma cells Basal lamina Steroid binding, rat, 1612 Tumor growth, guinea pig, 3211 Epithelium Melanoma(s) 3214 Mammary neoplasms, 1600 Animal model, albino guinea pig L,C leukemia cells Mammary neoplasms 3652 Tumor growth, guinea pig, 3214 MÃ©tastases,1600 12-O-Tetradecanoylphorbol-13- Hepatoma(s) MÃ©tastases acetate, 155 Antigens, neoplasm, 4197 Structural alterations, mouse Receptors, hormone Intralesional immunization, gui 1600 Hormonal control, 1612 nea pig, 4197 Steroid binding, rat, 1612 Tumor growth, guinea pig, 3211 Bay region epoxides Retinyl acetate 3214 Dibenzo(a,e)fluoranthene DNA synthesis, 1109 Immunization Liver microsomes, rat/mouse 4,4'-Stilbenediol, a,a'-diethyl- Neoplasm transplantation, 1036 1742 Mammary neoplasms, 1808 Immunotherapy BCNU Synergistic effect, rat, 1808 Tumor growth, guinea pig, 3214 see Urea, l,3-bis(chloroethyl)-l- 12-O-Tetradecanoylphorbol-13- Leukemia L1210 nitroso- Mouse, in vivo, 1967 acetate Leukemia LSTRA Carcinogenesis, trachea, rat, 4352 Mouse, in vivo, 1967 Benz(a)anthracene Two-stage carcinogenesis, hamster Lung neoplasms Aryl hydrocarbon hydroxylase 155

4876 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Benz(a)anthracene,9,10-dimethyl- Benzo(a)pyrene (cont'd) Benzo(a)pyrene hydroxylase (cont'd) Adenocarcinoma(s) Cytochrome P-450 Carcinogenic metabolites, 119 Methyltransferases, 417 Reduction of epoxide derivatives Benzo(a)pyrene 4,5-oxide 2910 Benzo(a)pyrene 4,5-oxide reducÃase Benzaldehyde Dibenzo-p-dioxin, 2,3,7,8- Cholanthrene, 3-methyl-, 2910 Cell transformation, viral tetrachloro- Virus, SV40, 2574 Liver microsomes, rat, 2910 Testis, rat, in vitro, 3297 Riboflavin, 2910 Benzenamine, .\, \-dimuthyl-4-Â«3- DNA adducts Glutathione transferases methylphenyDazo)- Radioimmunoassay quantitation, Conjugated metabolites, perfused Hemoglobin epidermal cells, 412 lung, rabbit, 101 Liver neoplasms, 1769 Endothelium Toxication/detoxication Hepatoma(s) Carcinogenic metabolite, bovine Conjugated metabolites, perfused Enzyme activity, 1658 cells, 1781 lung, rabbit, 101 Phospholipids, plasma membrane, Lung neoplasms rat, 909 Animal model, hamster, dog Benzo(c)phenanthrene 2288 V79-6 Chinese hamster cells Benzene Sustained release, 2288 Mutagenicity, 2876 Sister chromatid exchange Macromolecular binding Dihydrodiols/bay-region diol- Cell cycle kinetics, lymphocytes, Carcinogenic and noncarcinogenic human, 1189 epoxides metabolites, 207 Cytotoxic metabolites, 1189 Mutagenicity, 2876 Fibroblasts, hamster embryo, 207 Salmonella typhimurium Benzidine Metabolic activation site Mutagenicity, 2876 Benzidine, JV-hydroxy-MW-diacetyl- Steric inhibition, 1073 Skin neoplasms Carcinogenic metabolite, rodents Metabolism, lymphocytes, human Bay-region diol epoxides, 3910 751 Antipyrine elimination rate, 1305 Tumorigenicity, mouse, 3910 Hepatic enzyme activity, 751 Mono/dimethyl derivatives Prostaglandin endoperoxide synthe- Carcinogenic activity, skin, mouse Benzo(e)pyrene Diol-epoxides/tetrahydroepoxides tase 1073 Binding, renal medulla microx- Near-ultraviolet light Mutagenesis, 1985 omes, rabbit, 2839 Benzo(a)pyrene-DNA adducts Papilloma(s) Metabolism, 2839 245 Mouse, 1981 Skin neoplasms Benzidine, JV-hydroxy-AVV-diacetyl- DNA, 245 Single-strand breaks, 245 Dihydrodiols/diol-epoxides, 1981 Benzidine Nickel subsulfide Tumorigenicity, newborn mouse Carcinogenic metabolite, rodents Phagocytosis, 2688 203 751 Phenol, (l,l-dimethyI)-4-methoxy- Hepatic enzyme activity, 751 Benzo(e)pyrene, frans-4,5-dihydroxy- Anticarcinogenic activity, mouse 4,5-dihydro- Sulfotransferase 2824 Carcinogenic metabolite, rodents Skin neoplasms Liver microsomes, 2824 Tumorigenicity, newborn mouse 751 Structurally-related compounds 203 Benzo(a)anthracene Ames test, 642 Epoxide hydrolase Skin tumorigenicity, mouse, 642 Benzo(e)pyrene, irans-9,10-dihydroxy- Lymphocytes, fresh/mitogen- 9,1 (l-dihydro- Benzo(a)pyrene, iran.v-4,5-dihydni-4,5- Skin neoplasms stimulated, 2552 dihydroxy- Tumorigenicity, newborn mouse Benzo(a)pyrene Glutathione transferases 203 Aryl hydrocarbon hydroxylase Conjugated metabolites, perfused Enzyme inducibility, 1305 lung, rabbit, 101 Benzo(e)pyrene, fran5-9,10-dihydroxy- 9,10,11,12-tetrahydro- Carcinogenic metabolites Benzo(a)pyrene, irans-7,8-dihydro-7,8- Skin neoplasms Radioimmunoassay quantitation, dihydroxy- epidermal cells, 412 Tumorigenicity, newborn mouse Hepatocytes A549 human lung carcinoma cells 203 Cell transformation, neoplastic Cytotoxicity vs mutagenicity 1281 Benzo(j)fluoranthene 4070 Chromosomal damage, rat, 1281 Benzo(k)fluoranthene Hs703T human liver carcinoma cells Growth inhibition, rat, 1281 Mutagenic metabolites, 4528 Cytotoxicity vs mutagenicity Salmonella typhimurium, 4528 4070 Benzo(a)pyrene, 7,8-dihydrodiol 9,10- Hs835T human kidney carcinoma oxide Benzo(k)fluoranthene cells Escherichia coli Benzo(j)fluoranthene Cytotoxicity vs mutagenicity Mutagenicity vs Cytotoxicity Mutagenic metabolites, 4528 4070 3508 Salmonella typhimurium, 4528 Charcoal powder Benzo(a)pyrene, 7,12-dimethyl- 5,6-Benzoflavone Adenocarcinoma(s), 4301 Cyanic acid, sodium salt Polycyclic aromatic hydrocarbons Carcinoma, epidermoid, 4301 Chemical carcinogenesis inhibitor, Inhibition of carcinogenesis, 2774 Synergistic carcinogenesis, tra rat/mouse, 232 Molecular structure, 2774 chea, mouse, 4301 Chemiluminescence Benzo(a)pyrene hydroxylase 7,8-Benzoflavone Carcinogenic metabolites, 2002 Ethylene, chloro- Acetamide, N-fluoren-2-yl-

DECEMBER1980 4877 Subject Index to Volume 40

7,8-Benzoflavone (cont'd) Bladder neoplasms (cont'd) Blood platelets (cont'd) Liver microsomes, hamster/rat RBTCC carcinoma cells Mitogenic activity, 1212 3540 Morphological characteristics/ Aryl hydrocarbon hydroxylase tumorigenicity, 4571 Bone marrow neoplasms Enzyme inhibition, fetal cells, Epithelium Chromosome aberrations mouse, 424 Thiazole, 2-amino-4-(5-nitro-2- Therapy-induced malignancy Arylamide JV-hydroxylase furyl)-, 1897 4076 Flavone, 3,3',4',5,7-pentahydroxy- Liver microsomes, hamster/rat Bone neoplasms 3540 Carcinogenicity, rat, 3468 Procollagen Arylamine N-hydroxylase Formamide, JV-[4-(5-nitro-2-furyl)-2- Matrix proteins, 325 Liver microsomes, hamster/rat thiazolyl]- Sarcoma, Ewing's, 325 3540 Carcinogenic metabolites, rabbit/ Sarcoma, osteogenic, 325 Polycyclic aromatic hydrocarbons ram, 114 Bracken fern Inhibition of carcinogenesis, 2774 Ornithine decarboxylase, 1897 Flavone, 3,3',4',5,7-pentahydroxy- Molecular structure, 2774 Tumor growth, rat, 4524 Carcinogenicity, rat, 3468 ./V-Benzoyloxy-N-methyl-4- Urine, 4524 Kaempferol aminoazobenzene Kaempferol Carcinogenicity, rat, 3468 see Azobenzene, AT-benzoyloxy-N- Carcinogenicity, rat, 3468 methyl-4-amino- Mitomycin C Brain neoplasms Benzylamine, JV-methyl-jV-nitroso- Formamide, 7V-[4-(5-nitro-2- Gonadotropins, chorionic Organ specificity furyl)-2-thiazolyl]-, 261 Dibutyryl cyclic AMP, 4325 Carcinogenicity, rat, 1921 Intravesical administration, mouse Ornithine, a-methyl-. DL- Pharmacokinetics/metabolism, rat 261 Polyamines, 1961 2740 1-Naphthylamine Weibel-Palade bodies Bestatin Carcinogenicity, dog, 3537 Angiogenesis, 2010 Carcinoma M109 Prostaglandin E2 Diagnosis, 2010 Mouse, in vivo, 1967 Indomethacin, 3167 Leukemia LI210 Sodium saccharin Breast neoplasms Mouse, in vivo, 1967 Promoting agent, 734 Antineoplastic agents Leukemia LSTRA Ultrastructural study, rat, 734 Receptors, hormone, 2941 Mouse, in vivo, 1967 Bleomycin Carcinoembryonic antigen BHA Dipeptidyl hydrolase angiotensin- Isolation and characterization see Phenol, (l,l-dimethylethyl)-4- converting enzyme methoxy- 1181 Animal model, rat, 3621 Lectin/antibody affinity chroma- BifÃ¬dobacterÃ¬umhifidiim DNA, single-strand tography, 1181 Carcinoma, Ehrlich tumor Bacteriophage PM-2, 4173 Molecular weight/antigenic Bacteria distribution, mouse, in vivo Lung toxicity heterogeneity, 1181 2061 Animal model, rat, 3621 Carcinoma(s) Lactulose Meningea! carcinomatasis Cell morphology/cytoskeleton, Bacteria distribution, mouse, in vivo Urea hydrochloride, l-(4-amino-2- human, 3118 2061 methyl-5-, 1341 DNA synthesis, 1890 Microsomes, liver, mouse Glycoproteins, 316, 662 Bile salts Drug sensitivity assay, 4443 Methotrexate Post-treatment relapse, 1890 Nicotinamide adenine dinucleotide S-phase fractions, human, 1890 Drug uptake, hepatocytes, rat phosphate Tumor marker, 662 1852 DNA chain breakage, in vitro/in Hepatotoxicity, 1852 Chromosome aberrations vivo, 2051 Therapy-induced malignancy l,3-Bis(2-chloroethyl)-l-nitrosourea Liver microsomes, rat, 2051 4076 see Urea, l,3-bis(2-chloroethyl)-l- Walker 256 tumor cells Dehydroepiandrosterone nitroso- Urea hydrochloride, l-(4-amino-2- methyl-5-pyrimidinyl)methyl-3-(2- Radioimmunoassay, human breast l,4-Bis[2-[(2-hydroxyethyl)ammoJ- chloroethyl)-3-nitroso- cytosol, 3815 ethylamino)-9,10-anthracenedione DNA polymerase Blood platelets Cells, human, 3880 dÂ¡acetate a-Granules see 9,10-Anthracenedione. Drug therapy 1,4-bis((2-([2-hydroxyethyl)- Mitogenic activity, 1212 Ovarian/adrenal gland function amino]ethyl)amino)-. diacciate Leukemia L1210 4043 Megokaryocytopoiesis, mouse Review, 4335 Bladder neoplasms 667 Epidermal growth factor 1-Butanol, 4-(butylnitrosoamino)- Mammary tumor cells Dexamethasone, 2361 Urothelial regeneration response, Mitogenic activity, 1212 Insulin, 2361 rat, 3709 Neoplasm metastasis 17y3-Estradiol Butyric acid, 4-(JV-butyl-/V- Mitogenic activity, 1217 Antiestrogens, 1722 nitrosamine)- Neuro-2a cells Hormone therapy Ames test, 162 Mitogenic activity, 1212 Mathematical model, 2423 Butyric acid lactone, 4-(JV- R2C cells MÃ©tastases,2423 butylnitrosamino)-4-hydroxy- Mitogenic activity, 1212 Ovarian/adrenal gland function Ames test, 162 RAG cells 4043

4878 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Breast neoplasms (cont'd) 1 Butanont, 4-(/V-methyl-N-nitrosamino)- Butyrophenone, 4-[4-(p-chlorophenyl)-4- l-(3-pyridyl)-(cont'd) hydroxypiperidino]-4'-fluoro- Receptors, hormone, 2423 (cont'd) Post-treatment relapse Neuroepithelioma S-phase fractions, human, 1890 Carcinogenicity, rat, 298 DNA synthesis Antineoplastic analogs, human/ Prolactin JV-Butyl-N-O-carboxypropyDnitrosamine mouse cells, 1414 Lactalbumin, 486 see Butyric acid, 4-(JV-butyl-N- Menopause, 486 nitrosamine)- Melanoma(s), 1414 Normal vs neoplastic tissue, in 2(3)-ferf-Butyl-4-hydroxyanisole Mammary neoplasms vitro, 486 see Phenol, (l,l-dimethyl)-4- Dexamethasone, 1863 Proteinases methoxy- Tyrosinase Adenocarcinoma(s), 550 JV-Butyl-N-(4-hydroxybutyl)nitrosamine DNA polymerase, 1414 Fibroadenoma, 550 see 1-Butanol, 4-(butylnitrosoamino)- Secretion, in vitro, 550 Receptors, hormone 4*(jV-Butylnitrosamino)-4- Clinical correlations, male, 991 hydroxybutyric acid lactone Caffeine Dextran-coated charcoal vs su see Butyric acid lactone, 4-(JV- Antineoplastic agents crose gradient analyses, 4127 butylnitrosamino)-4-hydroxy- DNA repair, 1332 17/3-Estradiol, 1750 Carbamic acid, ethyl ester Butyric acid Caffeine-sensitive period, lung, Estrogen, 3357, 4821 Adenosine cyclic 3':5'- Estrogen sulfotransferase, 1360 mouse, 1332 monophosphate HeLa-S3 cells Hormonal manipulation, male Isoproterenol, 240 Neocarzinostatin, 3786 991 12-O-Tetradecanoylphorbol-13- Syrian hamster embryo cells Isolation and characterization acetate Cell transformation, neoplastic 3172 Receptors, /3-adrenergic, 240 2411 Megestrol acetate, 2557 Skin, mouse, 240 Thymidine incorporation, 2411 Progesterone, 1750, 3357, 4821 Butyric acid, 4-[p-bis(2- DNA repair Prognosis, 3357 chloroethyDaminophenyl]- C3H mouse embryo cells, 4415 Tamoxifen, 1750 HeLa cells Mutation Therapeutic response, 2557 DNA synthesis, 967 Escherichia coli, 1332 Remission duration Quinoline, 4-nitro-, 1-oxide S-phase fractions, human, 1890 Histones, 967 Histones Caffeine-sensitive period, lung, Retinole acid Posttranscriptional/ mouse, 1332 Binding protein, 4265 posttranslational inhibition Normal/dysplastic/neoplastic tis 967 sue, human, 4265 Calcitonin Therapy Butyric acid, 4-UV-butyl-N- nitrosamine)- Adenylate cyclase Review, 3863 BEN cells, 1311 Ames test Transplantation, heterologous Human breast cancer cells Bladder neoplasms, 162 Nude mouse, 95 Human breast epithelial cells Carcinogenic metabolites, 162 Receptors, hormone, 95 4764 Vascularization, 95 Butyric acid lactone, 4-UV- Receptors, hormone Virus, murine mammary butylnitrosamino)-4-hydroxy- BEN cells, 1311 Cells, human, 3880 Ames test Thyroid neoplasms Virus, retro- Bladder neoplasms, 162 Carcinoma(s), 1419 Cells, human, 3880 Carcinogenic metabolites, 162 Bromobenzene Butyric acid, sodium salt Calcium Chemiluminescence K-Balb 16 c cells Carcinogenic metabolites, 2002 Virus induction vs cell cycle Cell transformation, neoplastic Mouse epithelial cells, 4694 3886 Bromotriphenylethylene, trans isomer Gondaotropins, chorionic T51B rat liver cells Barbituric acid, 5-ethyl-5-phenyl- see Broparestrol Trophoblastic/nontrophoblastic cells, 4519 4541 Broparestrol Phorbol-12,13-di-decanoate, 4541 Mammary neoplasms Butyric acid, 2-amino-4-(ethylthio>-, Phorbol, 4-O-methyl-12-O- Prolactin, 1674 Carcinogenesis, chemical tetradecanoyl-, 4541 Prolactin Polypeptide, liver, rat, 4688 Saccharin, 4541 Receptors, hormone, 1674 DL-Ethionine, 4688 Mitochondria 1-Butanol, 4-(butylnitrosoamino)- y-Butyrolactone Cell transformation, neoplastic Bladder neoplasms Uracil, R ,S-1 -(tetrahydro-2-furanyl)- 221 Urothelial regeneration response, Antineoplastic agents, 2814 Leukemia(s), 221 rat, 3709 Butyrophenone, 4-[4-(p-chlorophenyl)-4- 1-Butanone, 4-UV-methylWV- hydroxypiperidino]-4'-flu oro- L-Canavanine nitrosamino)-l-(3-pyridyl)- Dexamethasone DNA synthesis Metabolism Prolactin, 1863 Antitumor activity, mouse, 535 Tumorigenicity, rat, 4144 Tumor growth inhibition, rat, 1863 L1210 cells, 535

DECEMBER 1980 4879 Subject Index to Volume 40

Carbamic acid, ethyl ester Carcinoembryonic antigen Carcinogens, chemical (cont'd) Adenoma(s) Breast neoplasms â€¢n-Glutamyltranspeptidase Virus, lÃ¡clatedehydrogenase, 64 Isolation and characterization Resistant hepatocytes, 1157 Ames test 1181 Nicotinamide adenine dinucleotide Liver system, rat/duck, 1194 Lectin/antibody affinity chroma- Lymphocytes, 1803 Caffeine tography, 1181 Virus, xenotropic Caffeine-sensitive period, lung, Molecular weight/antigenic Susceptibility vs virus production, mouse, 1332 heterogeneity, 1181 mouse, 4364 Hepatocytes, rat Carcinoma, oat cell Collagen gel-nylon mesh culture Prognosis, treatment, 4420 Carcinoma, Ehrlich ascites 3259 HCT-8 colonie carcinoma cells Ethylenediaminetetraacetic acid Cell proliferation, in vitro, 4092 Lung neoplasms Theophylline, 4744 Gastrointestinal neoplasms DNA synthesis, 4092 Virus, lÃ¡clatedehydrogenase, 64 1,10-Phenanthroline Tumor burden, diagnosis, 1300 Neoplasms IgG Cell proliferation, in vitro, 4092 Carcinogenicity/mutagenicity, Antigen-antibody complexes, 497 DNA synthesis, 4092 rat/mouse, 1194 Ovarian neoplasms, 502 Carcinoma, Ehrlich tumor Carbamic acid, hydroxy-, ethyl ester Radioimmunodetection, human Acetone, chlorohydroxy- Ames test patients, 497, 502 Deoxyhalo analogs, 3274 Liver system, rat/duck, 1194 Leukemia, acute nonlymphoblastic BifÃdobacteriumbifÃdum Neoplasms Serum/bone marrow cells, nor- Bacteria distribution, mouse, in vivo Carcinogenicity/mutagenicity, mal/neoplastic, 2039 2061 rat/mouse, 1194 Leukemia, chronic myelocytic Bleomycin Serum/bone marrow cells, nor- Nicotinamide adenine dinucleo Carbamic acid, vinyl ester mal/neoplastic, 2039 tide phosphate, 2051 Ames test Sialyltransferase Daunorubicin Liver system, rat/duck, 1194 Gastrointestinal neoplasms, 1300 Daunorubicin, JV-acetyl-, 1077 Neoplasms Undine, bromodexoy- Fatty acids Carcinogenicity/mutagenicity, Theophylline, 4744 Diet, 4606 rat/mouse, 1194 Synthesis, mouse, in vivo/in vitro 5-Carbamoyl-l/Ã¯-imidazol-4yl I- Carcinogens 4606 Human adamatanecarboxylate DL-Glycerol IARC monographs, 1 Antineoplastic agents Deoxyhalo analogs, 3274 Review, 1 Antitumor activity, mouse, 3810 Interferon Review Inhibitor, ascites fluid, 2534 5-CarbamoyI-1//- iinidu/,ul-4yI piperony- Epidemiology, China, 2633 Isolation and characterization late Carcinogens, chemical 2534 Antineoplastic agents Acetamide, N-fluoren-2-yl- Linoleic acid Antitumor activity, mouse, 3810 Polypeptide, liver, rat, 4688 Metabolism, 2447 Carbamylcholine Resistant hepatocytes, 1157 Methotrexate Adenosine cyclic 3':5'- Azobenzene, 3'-methyl-4- Adenosine cyclic 3':5'- monophosphate dimethylamino- monophosphate, 2400 Granulocyte-macrophage colony- Polypeptide, liver, rat, 4688 Palmitic acid forming units, 1223 DL-Butyric acid, 2-amino- Metabolism, 2447 Guanosine cyclic 3':5'- 4-(ethylthio)-, Phenol, 2,4-dinitro- monophosphate Polypeptide, liver, rat, 4688 Methotrexate, 3669 Granulocyte-macrophage colony- Concanavalin A l//-Pyrazolo(2,3-^)imidazole, 2,3- dihydro- forming units, 1223 Bladder, mouse, 2006 Leukemia, myelocytic Screening, 2006 Ribonucleotide reducÃase,3891 Cyclopenta(c,d)pyrene-3,4-oxide Undine, 5-deoxy-5-fluoro- Proliferation, human cells, 1223 Mutagenicity, 4482 Anlineoplaslic activity, in vivo/in Carbohydrates Cytochrome P-450 vitro, 3333 Cell membrane Metabolic activation, 1652 Platelet aggregation, 1217 Dibenzo-p-dioxin, 2,3,7,8- Carcinoma, epidermoid Neoplasm metastasis tetrachloro- Arylsulfatases Lung neoplasms, 3804 Platelet aggregation, 1217 Anticarcinogenic activity, female Cell transformation, neoplastic mouse, 1580 Carbon tetrachloride Serial passage, chorioallantoic Chlorinated hydrocarbon deriva Acetamide, Ar-fluoren-2-yl- membrane, chick embryo tives, 1580 In vivo carcinogenicity test, 1157 2310 Metabolic activation, 1580 Resistant hepatocytes, 1157 Mouse epithelial cells Skin neoplasms, 1580 2-Carboxylic acid, DL-y3-2- Transformation markers, 4694 Gene expression Charcoal powder aminobicyclo[2,2,l]heptane- DNA, 3374 Benzo(a)pyrene, 4301 Phenylalanine, L-p-(di-2- Drosophila melanogaster, 3374 L-Dopa decarboxylase chloroethylamino)- Genetics Diamine oxidase, 1990 Drug transport, 1144 Susceptibility vs virus production, In vivo vs in vitro activity, 1990 Sensitive/resistant cells, 1144 mouse, 4364 Formaldehyde

4880 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Carcinoma, epidermoid (cont'd) Carcinoma(s) (cont'd) Casein Carcinogenesis, mouse/rat, 3398 Morphological study, 2160 RNA, messenger Lung neoplasms Soft agar growth medium, 2160 Hormonal influences, mouse, 362 Nucleic acid synthesis, 2295 MDA-MB 134-468breast tumor MÃ©tastases cells Catechol Animal model, chick embryo Cell morphology/cytoskeleton, Saccharomyces cerevisiae 2300 human, 3118 Mitotic recombination/ Hep-3 cells, 2310 Cytoplasmic organelles mutagenicity, 2323 Plasminogen activator, 2300 Pleomorphism, normal/ Ultraviolet rays Serial passage, chorioallantoic nonmalignant/malignant tis Mitotic recombination/ membrane, chick embryo sues, 803 mutagenicity, 2323 2310 Ultrastructural study, human Plasminogen activator 803 Cathepsin D Serial passage, chorioallantoic Glycoprotein Sarcoma(s) membrane, chick embryo Isolation and characterization Caloric restriction, mouse, 1680 2310 316 Trachea! neoplasms Ultrastructural study, plasmalem- CCNU Cell cycle vs tumorigenicity ma, 316 see Urea, l-(2-chloroethyl)-3- 4467 Lung neoplasms cyclohexyl-1-nitroso- Cell subpopulations, rat, 4467 Nucleic acid synthesis, 2295 Carcinoma, Lewis lung Mammary neoplasms Cell adhesion Adriamycin Ovariectomized rat, 3112 Fibroblasts Liposomes, 1532 Ultrastructure, 3112 Medium change response, chicken Phosphodiesterase inhibitors Pancreatic neoplasms 1753 Growth inhibition, 1950 Serine, diazoacetate (ester), 592 Virus, Rous sarcoma, 1753 Phenylalanine, 5-S-cysteinyl-L-3,4- Glycoproteins Carcinoma M109 dihydroxy- Ml myeloid leukemia cells, 3387 Azimexon Antitumor activity, in vitro Retinoids Mouse, in vivo, 1967 2543 C3H/10T1/2CL8 mouse fibrob- Bacillus Calmette-Guerin Progesterone last cells, 3141 Mouse, in vivo, 1967 Mammary neoplasms, 1091 Bestatin Testicular neoplasms Cell culture Mouse, in vivo, 1967 Transplantation, heterologous Amine precursor uptake, 3502 Maleic anhydride-divinyl ether copo- 949 Carcinoma, oat cell lymer polyanions In vivo vs in vitro growth cha Decarboxylation, 3502 Mouse, in vivo, 1967 racteristics, 949 Growth requirements, 3502 Carcinoma, oat cell Thyroid neoplasms Carcinoma(s), 2160 Carcinoembryonic antigen Calcitonin, 1419 Epithelium Prognosis, treatment, 4420 Immunohistological/light and Preneoplastic cells, mouse, 3982 Cell culture electron microscopy, rat, 1419 Melanoma(s), 2160 Decarboxylation, 3502 Secretory granules, 1419 Ovarian neoplasms Growth requirements, 3502 Malignant effusion/abdominal NCI-H69 lung carcinoma cells Carcinoma, small cell washings, human, 2743 Cell culture, 4356 see Carcinoma, oat cell Sarcoma(s), 2160 NCI-N230 nude mouse tumor cells Soft agar growth medium Mechanical/enzymatic disaggrega- Cell culture, 4356 Carcinoma, squamous cell L-Dopa decarboxylase see Carcinoma, epidermoid tion, 2160 Diamine oxidase, 1990 Morphological study, 2160 In vivo vs in vitro activity, 1990 Cell cycle Lung neoplasms Carcinosarcoma, Walker 256 Guanine, 6-thio- Cell self-renewal, 1820 Cyclophosphamide L-Phenylalanine mustard, 830 Cytotoxicity, mouse, 1458 Clonal heterogeneity, human cells Leukemia L1210 cells, 1458 4295 Mammary neoplasms Colony growth, 1820 Carminomycin Virgin/parous rat, 2677 Hepatoma, Novikoff Phenylalanine, L-p-(di-2- Carcinoma, renal cell Antitumor activity, 387 see Adenocarcinoma(s) chloroethylamino)- Leukemia L1210 RPMI 6410 cells, 1169 Carcinoma(s) Antitumor activity, 387 Pyrazole, 2,3-dihydro-l//-imidazo Breast neoplasms Carminomycin-11-methyl ether [1.2-6]- DNA synthesis, 1890 Hepatoma, Novikoff Leukemia L1210 cells, 1103 Glycoproteins, 316, 662 Post-treatment relapse, 1890 Antitumor activity, 387 P388 cells, 1103 S-phase fractions, human, 1890 Leukemia LI210 Cell differentiation Antitumor activity, 387 Tumor marker, 662 Ascitic fluid Cell culture Carrageenan Ml myeloid leukemia cells, 3387 Mechanical/enzymatic disaggrega- Leukemia L1210 HL-60 leukemia cells tion, 2160 Vaccines, 3832 L-Ethionine, 3206

DECEMBER 1980 4881 Subject Index to Volume 40

Cell differentiation (cont'd) Cell proliferation (cont'd) Cell transformation, neoplastic (cont'd) MIRW human melanoma cells Neoplastic vs nonneoplastic cell Colchicine, 2383 Retinoids, 2194 lines, 1249 Collagenase, 2383 Ml mouse myeloid leukemia cells Cytochalasin B, 2383 Colony stimulating factor, 4804 Cell survival Ornithine decarboxylase Hyaluronidase, 2383 D-factor, 4804 Surface-related changes, 2383 Puromycin, 432 Dexamethasone Trypsin, 2383 Ml myeloid leukemia cells, 3387 Cell transformation, neoplastic Mitochondria Adenosine cyclic 3':5'- Dibutyryl cyclic AMP Calcium transport, 221 Ml myeloid leukemia cells, 3387 monophosphate Nickel subsulfide Epithelium Proteins, 2860, 2884 Embryo cells, hamster, 2688 Morphological/biochemical cha Arginine Ovary cells, hamster, 2688 racteristics, trachea, hamster Fibronectin, 2562 Phagocytosis, 2688 4403 Ascorbic acid Pancreatic neoplasms Erythroleukemia C3H/10T1/2 mouse embryo cells DNA synthesis, 3443 Ornithine decarboxylase, 1727 2796 Plasminogen activators Polyamines, 1727 Benzo(a)pyrene, (+ )-trans-7,8- Fibrinolytic activity, hamster cells Hepatoma(s) dihydro-7,8-dihydroxy- 1438 Enzyme activity, 725 Hepatocytes, 1281 Semisolid agar growth, hamster Phenotype diversity, 725 Caffeine cells, 1438 Interferon Syrian hamster embryo cells Retinoids Leukemia, myelocytic, 2919 2411 C3H/10T1/2CL8 mouse fibrob Leukemia, myelocytic A31 3T3 cells last cells, 3141 Prostaglandins E, 2512 Proteins, 2860 3T12 fibroblast cells, 1944 Lysozyme BALB/3T3 cells Cellular adhesion, 1944 Myeloid leukemia cells, 914 Proteins, 2860 RL34 cells Prostaglandins E C3H/10T1/2 mouse embryo cells Adenosine 5'-triphosphatase Ml myeloid leukemia cells, 3387 Radiation, ionizing, 3328 1318 12-O-Tetradecanoylphorbol-13- C3H/10T1/2 fibroblast cells Epithelial cells, liver, 1318 acetate Chromosome aberrations, 4254 Ultrastructural study, 1318 Friend erythroleukemia cells, 3369 DNA, 4254 RNA, messenger 3780 MCA3T3 cells Normal/hyperplastic/neoplastic Neural crest cells, 2465 Proteins, 2860 liver, rat, 3713 Melanocytes, chick embryo, 2465 Mouse epithelial cells 12-O-Tetradecanoylphorbol-13- Calcium, 4694 acetate Cell membrane Transformation markers, 4694 C3H 10T1/2 cells, 1915 Adenosine cyclic 3':5':monophos- Colonie neoplasms Theophylline phate Growth characteristics/ Syrian hamster embryo cells Proteins, 2860 tumorigenicity, mouse cell lines 2411 Carbohydrates 2142 Ultraviolet rays Platelet aggregation, 1217 Concanavalin A Methanesulfonic acid, methyl es Galactoproteins Agarose bead complex, 4663 ter, 582 AS-30D hepatocellular carcinoma DNA repair X-rays, 582 cells, 2853 Cell cycle, 4415 Urea, hydroxy- Isolation/characterization, 2853 C3H mouse embryo cells, 4415 Syrian hamster embryo cells Lipids Epidermoid carcinoma 2411 Platelet aggregation, 1217 Serial passage, chorioallantoic Virus, herpes simplex type 2 Proteins membrane, chick embryo Ultraviolet rays, 2213 Platelet aggregation, 1217 2310 Epithelium Virus, SV40 Viral proteins, 2213 Cell membrane potential Morphological/biochemical cha Electrical properties racteristics, trachea, hamster Normal/neoplastic cells, rat/ 4403 Cell transformation, viral mouse, 1830 Fibronectin Antibodies, neoplasm Liver epithelial cells, mouse Binding, cultured/freshly isolated Cell nucleus 2562 neoplastic cells, 3602 Phorbol esters Galactoproteins Benzaldehyde Isolation/characterization, 2853 Site of action, 1066 Guanidine, JV-methyl-JV'-nitro-AT- Virus, SV40, 2574 Swiss 3T3 mouse cells, 1066 3BM-78 cells 12-O-Tetradecanoylphorbol-13- nitroso- Leukopoietic differentiation, acetate Syrian hamster embryo cells mouse, 866 Site of action, 1066 2411 BHK cells Swiss 3T3 mouse cells, 1066 Hydrazine, 1,2-dimethyl- Sialic acid, 1550 Colonic neoplasms, 1774 Virus, Rous sarcoma, 1550 Cell proliferation Kidney neoplasms TPA30-1 transformed placental cells Epithelium Polypeptides, 3728 Gonadotropins, chorionic, 4025 Liver factors, rat, 1249 Mammary neoplasms 3T3 cells

4882 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

3BM-78 cells (cont'd) Cell transformation, viral (cont'd) AS-30D hepatocellular carcinoma cells Retinole acid, 3089 Galactoproteins Specific esterase inhibition, mouse Cytochalasin B Isolation/characterization, 2853 866 Tumorigenicity/soft agar cell Virus, Friend leukemia Cell transformation, viral, 866 growth, 4410 Ascites tumor cells Fibroblasts Glucose B16 melanoma cells Medium change response, chicken Electrophoretic mobility, 4751 Adenosine 1753 Oxygen Cytostasis, neoplastic vs normal Virus, Rous sarcoma, 1753 Electrophoretic mobility, 4751 cells, mouse, 2147 NRK cells Cell-mediated Cytotoxicity, spleno- Iron, 786 A31 3T3 cells cytes, mouse Ornithine decarboxylase Cell transformation, neoplastic Letter to the editor, 1762, 1763 Rat-1 fibroblasts, 604 Proteins, 2860 Guanosine Cytostasis, neoplastic vs normal Ribonuclease cells, mouse, 2147 Seminal plasma, bovine, 3740 A549 human lung carcinoma cells Lung neoplasms Salmonella typhimurium Benzo(a)pyrene Cell surface properties, 1645 NL2/NL3/NL4 lymphoblastoid Cytotoxicity vs mutagenicity MÃ©tastases,1645 cells, 4775 4070 MÃ©tastases Organ selectivity, mouse, 2281 Sister chromatid exchange Tissue invasiveness variants, 1636 NL2/NL3/NL4 lymphoblastoid B16 melanoma cells cells, 4775 Plasminogen activator C57BL/6J spleen cells Neoplasm metastasis, 288 Virus, adeno 2 Methotrexate RNA, viral, 3177 Immunosuppression, 650 Virus, Epstein-Barr BALB/c lung carcinoma cells C57BL/K8 lymphoid cells NL2/NL3/NL4 lymphoblastoid Antigens, neoplasm Virus, radiation leukemia cells, 4775 Identification and characterization Quantitative assay, 544 2153 Virus, Friend leukemia Caki cells 3BM-78 cells, 866 Vasoactive intestinal peptide BALB/3T3 cells Adenosine cyclic 3':5'- Virus, herpes simplex 2 Cell transformation, neoplastic monophosphate, 2529 Antibodies, viral, 2074 Proteins, 2860 Antigens, viral. 2074 Carcinoma cells, human Cell surface proteins, 713 Uracil, 5-fluoro- Total hemolytic complement, BEN cells dTMP-synthetase, 4113 serum, hamster, 713 Adenylate cyclase Calcitonin, 1311 Cardiac mammalian cells Virus, Kirsten sarcoma Calcitonin Adriamycin Butyric acid, sodium salt, 3886 Receptors, hormone, 1311 Cardiac toxicity, 4133 Virus induction vs cell cycle 3886 Choriocarcinoma LÃ¡clatedehydrogenase-Z, 3408 CBT brain tumor cells Virus, polyoma LÃ¡clatedehydrogenase-Z Dibutyryl cyclic AMP Gonadotropins, chorionic, 4325 RNA, viral, 3177 Isoenzyme, trophoblast cell, 283 Virus, SV40 CCL 137 lung fibroblast cells Antigens, fetal, 1380 BHK 21/C13 hamster cells Collagenase Antigens, neoplasm, 1380 Adenine, 9-/3-D-arabinofuranosyl- Procollagen, 4722 Antigens, surface, 1380 Cytotoxicity, 4123 Adenine, 9-/8-D-arabinofuranosyl, 5'- Fibronectin Neoplasm transplantation, 1380 8387 fibrosarcoma cells, 4722 RNA, viral, 3177 monophosphate Fibronectin-releasing activity Cytotoxicity, 4123 4722 Cell transformation, viral 6410 RPMI cells Sialic acid, 1550 Phenylalanine, L-p-(di-2- Virus, Rous sarcoma, 1550 CCRF-CEM cells chloroethylamino)- Sialic acid Adenine, 9-/3-D-arabinofuranosyl- Cell cycle, 1169 Glycoproteins, 1550 Cytotoxicity, 1405 Deoxycoformycin, 2349 3BM-78 cells DNA synthesis, 1405 Adenine, 9-/3-D-arabinofuranosyl-2- A-374 melanoma cells Cell transformation, viral DNA polymerase Leukopoietic differentiation, fluoro- Tissue distribution, normal/ mouse, 866 Cytotoxicity, 1405 neoplastic, human, 4398 Phorbal-12,13-benzoate Deoxycoformycin, 2349 Specific esterase inhibition, mouse DNA synthesis, 1405 AKR leukemia cells 866 Methyladenosine phosphorylase Daunorubicin 12-O-Tetradecanoylphorbol-13- Polyamine metabolism, 4178 Cytotoxicity, 2835 acetate Thymidine

DECEMBER 1980 4883 Subject Index to Volume 40

CCRF-CEM cells (cont'd) C3H/10T1/2 mouse embryo cells HA-1 Chinese hamster ovary fibroblast Cytidine, 5'-triphosphate, deoxy- (cont'd) cells 1718 Anthracylic antibiotics Hyperthermia Growth inhibition, 1718 Cardiotoxicity, mechanism, 4581 Guanosine, 5'-triphosphate, Effect of cell medium, 4501 Antineoplastic agents Thermotolerance deoxy-, 1718 Agent screening assay, 943 Effect of cell medium, 4501 Ribonucleotide reducÃase,1718 Cell proliferation vs invasiveness HBL-100 humanbreast cells CCRF-HSB-2 cells 943 Directional migration, 943 Human breast cancer cells Methionine Mitogenic activity, 4385 Normal vs malignant cells, 634 Cell transformation, neoplastic Ascorbic acid, 2796 Plasminogen activator, 4385 Chromosome aberrations, 4254 HC-252 hepatocellular carcinoma cells DNA, 4254 Oxidoreductase enzymes CHO cells Cyclopenta(c,d)pyrene-3,4-oxide Adriamycin Cell proliferation vs enzyme ac Mutagenicity, 4482 tivity, 4677 Cytotoxicity vs cell cycle, 3437 Cytidine, 5-aza Hyperthermia HCT-8 colonie carcinomacells Mezereine, 334 Carcinoembryonic antigen pH vs cytotoxicity, 4019 12-O-Tetradecanoylphorbol-13- Nogalamycin Theophylline, 4744 acetate, 334 Cytotoxicity vs cell cycle, 3437 Undine, bromodexoy-, 4744 6//-Pyrido(4,3-o)carbazoIe, 5,11- Tumor promoters, 334 HeLa cells dimethyl- Tumor promotion inhibitors, 334 Drug therapy Cytotoxicity, 2390 DNA repair Animal model, nude mouse, 4287 12-O-Tetradecanoylphorbol-13- Cell cycle, 4415 Hyperthermia acetate Fluorescent light, 4415 Cytotoxicity, 3459 Chromosome aberrations, 3245 Hyperthermia Glucose, 3459 Urea, TV-ethyl-N-nitroso- Amphotericin B, 3763 Hypoxia, 3459 Malignancy vs heat/antibiotic sen DNA repair, 2623 Vasoactive intestinal peptide sitivity, 3763 Adenosine cyclic 3':5'- Mutagenicity, 2623 Phosphodiesterase inhibitors monophosphate, 2529 Urea, TV-methyl-N-nitroso- Growth inhibition, 1950 DNA repair, 2623 Radiation, ionizing Mutagenicity, 2623 Cell transformation, neoplastic HeLa-S3 cells CRL IUÃŒ/1221/1223 fibroblast cells 3328 Antigens, neoplasm Acetamide, JV-(acetyloxy)-JV-9-//- Cytotoxicity, 3328 Identification and purification fluoren-2-yl Retinoids 3194 Hvdrocortisone DNA repair, 4313 Cell transformation, neoplastic 3141 Urea, l-(2-chloroethyl)-3- Xeroderma pigmentosum, 4313 12-O-Tetradecanoylphorbol-13- cyclohexyl-1-nitroso-, 3697 CT26 carcinoma cells acetate Neocarzinostatin Colonie neoplasms Cell transformation, neoplastic Caffeine, 3786 MÃ©tastases,2142 1915 Cell cycle, 2405 Morphological changes, 4709 Cell cycle block, 3786 CI 36 carcinoma cells Embryo fibroblastcells Dibutyryl cyclic AMP, 3786 Colonie neoplasms DNA repair, 2405 MÃ©tastases,2142 Prostaglandin EÂ¡ Lymphocyte-stimulated produc DNA, single strand, 2405 ("151 carcinoma cells tion, rat, 3167 Theophylline, 3786 Colonie neoplasms Hep Gj humanhepatomacells MÃ©tastases,2142 EMT-6 mouse adenosarcoma cells 12-O-Tetradecanoylphorbol-13- Mitomycin C acetate Oil/He mammary carcinoma cells Hypoxia, 2356 Phorbol-12-13-didecanoate, 4433 Macrophages Tumor spheroids Wheat germ agglutinin, 3798 Cell characteristics, 3956 Hep-3 cells Neoplasm transplantation Epidermoid carcinoma Growth characteristics, lung, Epithelial cells MÃ©tastases,2310 mouse, in vivo, 3495 Prostaglandin E2 MÃ©tastases Lymphocyte-stimulated produc Animal model, chick embryo C3H mouse embryocells tion, rat, 3167 2300 DNA repair Caffeine, 4415 Fibroblastic cells, human, mouse HKC-400 renal carcinoma cells Uracil, 5-fluoro- Cell cycle, in vitro vs in vivo, ham C3H/10T1/2 mouse embryo cells dTMP-synthetase, 4113 ster, 4796 Adriamycin Daunorubicin, 4581 Friend erythroleukemia cells 111,-60 leukemia cells Aflatoxin B, 6H-Pyrido(4,3-b)carbazole, 5,11- Adenosine cyclic 3':5'- DNA, 2904 dimethyl- monophosphate Alkylating agents Cytotoxicity, 2390 Colony formation, 1858 Cytotoxicity, 682 12-O-Tetradecanoylphorbol-13- Adenosine cyclic 3':5'- DNA synthesis, 682 acetate monophosphate, N', O2'- Mutagenesis, 682 Cell differentiation, 3780 dibutyryl

4884 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

HL-60 leukemia cells (cont'd) KG-1 cells (cont'd) 1.1210leukemia cells (cont'd) Colony formation, 1858 Colony formation, 1858 Sulfido derivatives, 4216 Cell differentiation Cytosine, 1-/3-D-arabinofuranosyl- K562 leukemiacells L-Ethionine, 3206 Deoxycytidine kinase, 3286 Colony-stimulating factor Methyladenosine phosphorylase Polyamine metabolism, 4178 Thymidine, 1525 Colony formation, 1858 9-/J-D-Arabinofuranosyl-2- Granulocytes L cells fluoroadenine Methyl sulfoxide, 1469 Immunity, cellular Deoxycytidine kinase, 3610 Prostaglandins E Tumorigenicity vs immunological Tumorigenicity, in vivo/in vitro Colony formation, 1858 properties, 3252 3610 Receptors, complement Interferon Diguanidine, 1, l'-((methylethanediylidene)dini- Cell maturity, 1469 Virus, Newcastle disease, 2919 12-O-Tetradecanoylphorbol-13- trilo)- LAN-1 tumorcells acetate Mitochondrial damage, mouse, in Extracellular matrix digestion Cell maturity, 1469 vivo, 4533 Smooth muscle cells, rat, 3222 Granulocytes, 1469 Polyamines, 4533 Lipids, 3674 L2C leukemia cells S-Adenosylmethione decarboxy- NADPH oxidase, 1469 Immunotherapy lase, 4533 Tumor growth, guinea pig, 3211 Epipodophyllotoxin, 4'-de- Hs703T humanliver carcinomacells methyl-, 9-(4,6-O2- thenylidene-/3-D- Benzo(a)pyrene Line 10 hepatocarcinomacells glucopyranoside) Bacillus Calmette-Guerin Cytotoxicity vs mutagenicity DNA, 4225 4070 Tumor growth, guinea pig, 3211 Synergistic effects, 4225 3214 D-Glucopyranose, 2-(3-(2- Hs835T humankidney carcinomacells Immunotherapy chloroethyl)-3-nitrosoureido)-2- Benzo(a)pyrene Tumor growth, guinea pig, 3211 deoxy- Cytotoxicity vs mutagenicity 3214 Listeria monocytogenes Cytotoxicity, 3723 4070 Lithocholic acid Tumor growth, guinea pig, 3211 Hs939 melanomacells Propionibacterium acnes DNA repair, 2666 Retinoids Tumor growth, guinea pig, 3211 DNA, single strand, 2666 Phorbol myristate acetate, 3345 6H-Pyrido(4,3-b)carbazole, 5,11- Streptococcus mutans dimethyl- Tumor growth, guinea pig, 3211 HT29 cells Cytotoxicity, 2390 LoVo cells Colonie neoplasms, 1574 Theophylline Uracil, 5-fluoro- Colonie neoplasms Urea, l,3-bis(2-chloroethyl)-l- Tumor growth kinetics, athymic Drug resistance, 1574 nitroso-, 2202 mouse, 2846 Urea, l,3-bis(2-chloroethyl)-l- Isolation and characterization, Mitomycin C subpopulation, 1574 nitroso- Cell cycle kinetics, 1973 Cytotoxicity, 3723 DNA flow, 1973 Human breast cancer cells Uridine-cytidine kinase HBL-100 human breast cells LS174T cells Inhibitory pyrimidine nucleosides Mitogenic activity, 4385 Adenocarcinoma(s) 3559 Plasminogen activator, 4385 Colonie neoplasms, 1443 Isozymes, 3559 Human breast epithelial cells Colonie neoplasms Vinblastine Adenylate cyclase, 4764 Genetic signature analysis, 1443 Cell proliferation, 2695 Calcitonin, 4764 I.SISOcells Vincristine Receptors, 4764 Adenocarcinoma(s) Cell proliferation, 2695 Vitamin D,, 1,25-dihydro-, 4764 Vindesine Colonie neoplasms, 1443 Adenosine cyclic 3':5'- Colonie neoplasms Human breast epithelial cells Chromosome translocations monophosphate, 2695 Human breast cancer cells 1443 Cell proliferation, 2695 Adenylate cyclase, 4764 Genetic signature analysis, 1443 Calcitonin, 4764 Receptors, 4764 Lymphoidcells Transplantation, heterologous Mammarycells Vitamin Dâ€ž1,25-dihydro-, 4764 Aflatoxin B, Splenectomy and/or irradiated Human solid tumor cells Metabolic activation, 1836 nude mouse, 2588 Benz(a)anthracene, 7,12-dimethyl- Drug therapy Transplantation, homologous Antineoplastic agents, 4438 Metabolic activation, 1836 Splenectomy and/or irradiated Organ-specific carcinogenesis KG-1 cells nude mouse, 2588 Adenosine cyclic 3':5'- 1836 1.12Â»)leukemia cells Blood platelets monophosphate, N6, O2'- Adriamycin Mitogenic activity, 1212 dibutyryl Ricin, 3735 Colony formation, 1858 Anthracycline antibiotics Colony-stimulating factor Drug uptake, 4669 MCA 3T3 cells Colony formation, 1858 Nuclear cytoplasm, 4669 Cell transformation, neoplastic Prostaglandins E Cyclophosphamide Proteins, 2860

DECEMBER 1980 4885 Subject Index to Volume 40

NHIK 3025 carcinoma cells (cont'd) MCF-7 breast cancer cells MOPC 104E myeloma cells DNA polymerase Cyclophosphamide DNA single strand, 2915 Receptors, hormone, 1722 IgM, 2372 Sister chromatid exchanges, 2915 Epidermal growth factor, 2361 Plateau phase, mouse, 2372 Vincrisline Receptors, hormone Platinum(II)-diamminedichloro-, cis 1-Propargyl-S-chlororpyrimidin^- Isolation and characterization IgM, 2372 one, 2069 3172 Plaleau phase, mouse, 2372 X-rays Urea, l,3-bis(2-chloroelhyl)-l- DNA single strand, 2915 MCG-T14 mouse mammary tumor cells nitroso- Sister chromatid exchanges, 2915 Plasminogen activator IgM, 2372 Mitogenic activity, 4385 NL2/NL3/NL4 lymphoblastoid cells Plateau phase, mouse, 2372 Salmonella typhimurium MDA-MB 134-468 breast tumor cells Cell transformaron, viral, 4775 Carcinoma(s) MOPC-315 myeloma cells Sister chromatid exchange Cell morphology/cytoskeleton, Antibody, antiidiolypic Cell Iransformalion, viral, 4775 human, 3118 IgA, 1630 Virus, Epstein-Barr . MDA-231 breast cancer cells Freund's adjuvant Cell transformalion, viral, 4775 Epidermal growth factor, 2361 Cytoloxicily, 1630 OMEGA-Z cells Metholrexale Me-43 melanoma cells Choriocarcinoma Drug uplake, 4768 P3-NSI/lAg4 melanoma cells LÃ¡clale dehydrogenase-Z, 3408 Liposome binding, 4768 Antibody specificity, 2523 Milomycin C PC-3 cells Hybridoma(s), 2523 Anlilumor cyloloxicily, spleen Cylogenelics Melanoma S91 cells cells, 4565 Hyperdiploidy, 524 Retinoids Polyethylene glycol 6000 PC-5-PI cells Growth inhibition, in vitro, 1097 Antilumor cylotoxicity, spleen Proslale neoplasms Retinoic acid-binding protein, 1097 cells, 4565 2,6,10,14-Telramelhylpenladecane Cytogenetics, 524 MH134 hepatoma cells Neoplasm Iransplanlalion, 2229 P3-NSI/1 A(>4 melanoma cells Macrophages Me-43 melanoma cells Wheat germ agglutinin, 3798 Mouse epithelial cells Anlibody specificily, 2523 MIRW human melanoma cells Cell Iransformalion, neoplaslic Hybridoma(s), 2523 Retinoids Calcium, 4694 P3HR-1 human lymphoblastoid cells Cell differentiation, 2194 Transformalion markers, 4694 Tyrosinase, 2194 Fusobacterium nucleatum Anligen induclion, 4329 Ml mouse myeloid leukemia cells MPC-11 cells Anligens, viral, 4329 Colony stimulating factor 2,6,10,14-Telramethylpentadecane Virus, Epslein-Barr, 4329 Cell differentiation, 4804 Neoplasm transplanlation, 2229 D-factor P388 murine leukemia cells Cell differentiation, 4804 S107 myeloma cells Adenosine cyclic 3':5'- Glycoproteins Antibodies, cytotoxic monophosphale Cell differentiation, 3387 Differenlial susceplibilily, cell cy Phosphodieslerase, 1955 Interferon cle, 56 Polyinosinic-polycytidylic acids Adriamycin 2919 Liposomes, 1532 N-18 mouse neuroblastoma cells MLF cells Adenosine cyclic 3':5'- //-Pyrazolo(3,4-d)pyrimidin-4-ol DNA repair Tumor growlh inhibilion, mouse monophosphate Postreplication repair, mouse 1885 Binding prolein, 4100 1867 Uracil, 5-fluoro- Namalwa cells Sensilive vs resislanl cells, 1431 MM48 mammary carcinoma cells Anligens, neoplasm Transport and metabolism, 1431 Macrophages Idenlificalion and purificalion Vaccines Wheat germ agglutinin, 3798 3194 Carrageenan, 3832 MOLT-4F lymphoblast cells Immune response, mouse, 3839 Adenine, 9-/3-D-arabinofuranosyl, 5'- NCI-H69 lung carcinoma cells Mitomycin C, 3839 Carcinoma, oal cell triphosphate Potenlialion immune response, Cell cullure, 4356 Ribonucleotide reducÃase, 3555 mouse, in vivo, 3832 Cytosine, 9-ÃŸ-D-arabinofuranosyl, NCI-N230 nude mouse tumor cells 5'-triphosphate R2C cells Carcinoma, oal cell Blood plalelels Cell cullure, 4356 Ribonucleotide reducÃase, 3555 Milogenic aclivily, 1212 Deoxyadenosine triphosphate Neural crest cells Ribonucleotide reducÃase, 3555 12-O-Telradecanoylphorbol-13- RAG cells Methyladenosine phosphorylase Blood plalelels acetate Polyamine melabolism, 4178 Milogenic aclivily, 1212 Cell differentiation, 2465 Uridine, 5-iodo-2'-deoxy, 5'- Cell Iransformalion, viral triphosphate NHIK 3025 carcinoma cells Temperalure-sensilive viral mu- Ribonucleotide reducÃase, 3555 Hematoporphyrin lanls, 604

4886 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

RAG cells (cont'd) Syrian hamster embryo cells V-79 Chinese hamster cells (cont'd) Ornithine decarboxylase Caffeine Propylamine, 2-hydroxymethyl-Ar- Cell transformation, viral, 604 Cell transformation, neoplastic nitroso- Putrescine, 604 2411 Ames test, 3463 Virus, Rous sarcoma, 604 Thymidine incorporation, 2411 12-O-Tetradecanoylphorbol-13- Cell transformation, neoplastic acetate Raji cells DNA repair, 582 Chromosome aberrations, 3245 Methyladenosine phosphorylase Guanidine, /v'-methyl-./V-nitnx/V- Polyamine metabolism, 4178 Walker 256 tumor cells nitroso- Urea hydrochloride, l-(4-amino-2- RBTCC carcinoma cells Cell transformation, neoplastic methyl-5-pyrimidinyl)methyl-3-(2- Formamide, N-(4-(5-nitro-2-furyl)-2- 2411 chloroethyl)-3-nitroso- thiazolyl)- Thymidine incorporation, 2411 Bleomycin, 1341 Morphological characteristics/ Theophylline tumorigenicity, 4571 Cell transformation, neoplastic WAZ-2T cells 2411 Mammary neoplasms RD tumor cells Thymidine incorporation, 2411 Tumorigenicity, mouse, 1812 Extracellular matrix digestion Transformation, neoplastic WAZ-2TI + SA) adenocarcinoma cells Smooth muscle cells, rat, 3222 Aneuploidy, 91 Tumor spheroids REI cells Multistage model, 91 Urea, hydroxy- Spheroid attachment, 4631 Virus, herpes simplex 2 WI-38 fibroblast cells Antigens, viral, 2074 Cell transformation, neoplastic 2411 Angelicin RL34 cells Thymidine incorporation, 2411 DNA repair, 696 Cell transformation, neoplastic Cytosine, 1-/3-D-arabinofuranosyl-5'- Adenosine 5'-triphosphatase TEPC 15 myeloma cells Methotrexate monophosphate 1318 Sialic acid, 1940 Drug uptake, 4768 Epithelial cells, liver, 1318 Sialoglycoproteins, 1940 Liposome binding, 4768 Ultrastructural study, 1318 Sialyltransferases, 1940 TE85 tumor cells Cytosine, 1-/3-D-arabinofuranosyl-5'- RPMI 3460 Syrian hamster cells Extracellular matrix digestion triphosphate Receptors, hormone Smooth muscle cells, rat, 3222 Sialic acid, 1940 Glucocorticoids, 2174 TPA30-1 transformed placenta! cells Sialoglycoproteins, 1940 S-49 lymphoma cells Gonadotropins, chorionic Sialyltransferases, 1940 Pyrimidines, 5-fluoro- Adenosine cyclic 3':5'- 8-Methoxypsoralen DNA repair, 696 Toxicity vs cell cycle, 4209 monophosphate, 4025 SaD2 fibrosarcoma cells Dibutyryl cyclic AMP, 4025 Polyribosomes TPDMT-4 mammary tumor cells WIRL-3C epithelial cells Tumor suppression, mouse, 1501 Sublines Fibronectin Pronase Pregnant mouse, 3361 Arginine, 2562 Serra tÃamarcescens, 1501 Cell transformation, neoplastic RNAse TS1B rat liver cells 2562 SerrarÃa marcescens, 1501 Barbituric acid, 5-ethyl-5-phenyl- Calcium, 4541 10E2 mouse cells Sarcoma 180 cells Virus, herpes simplex type 2 Mitomycin C DNA synthesis, 4541 Phorbol-12,13-di-decanoate Cell transformation, neoplastic Hypoxia, 2356 Calcium, 4541 2213 SCK tumor cells DNA synthesis, 4541 Virus, SV40 Hyperthermia Phorbol, 4-O-methyl-12-O- Cell transformation, neoplastic Heat sensitivity, in vivo/in vitro tetradecanoyl- 2213 1130 Calcium, 4541 Vascular occlusion, 1130 DNA synthesis, 4541 3T3 cells Saccharin Guanidine, JV-methyl-W-nitro-./V- SC115 mouse mammary carcinoma Calcium, 4541 nitroso- cells DNA synthesis, 4541 Nicotinamide adenine dinucleo- Transplantation, neoplasm tide, 1797 Androgen, 4781 V-79 Chinese hamster cells Benz(a)anthracene, 7,12-dimethyl- Phorbol esters SK-L7 cells Cell nucleus, 1066 Mutagenesis, 1836 Thymidine Benzo(c)phenanthrene Retinoic acid Uracil, 5-fluoro-, 1543 Mutagenicity, 2876 Cell transformation, viral, 3089 Dipropylamine, 2,2'-dihydroxy-Ar- SKCO-1 cells Plasminogen activator, 3089 nitroso- 12-O-Tetradecanoylphorbol-13- Adenocarcinoma(s) Blastogenesis inhibition factor, 29 Ames test, 3463 acetate Dipropylamine, 2,2'-dioxo-N-nitroso- Cell nucleus, 1066 Solid tumor cells Ames test, 3463 Soft agar Nitrosoureas 3924A hepatoma cells Cell culture, 4151 Mutagenicity/cytotoxicity, 2719 Cyclophosphamide

DECEMBER 1980 4887 Subject Index to Volume 40

3924A hepatoma cells (cont'd) Charcoal powder 2-(3-(2-Chloroethyl)-3-nitrosoureido)-2- Neoplasm growth, 2179 Benzo(a)pyrene deoxy-D-glucopyranose Pyrazofurin Adenocarcinoma(s), 4301 see D-Glucopyranose, 2-(3-(2- Cell cycle, 2869 Carcinoma, epidermoid, 4301 chloroethyl)-3-nitrosoureido)-2- Synergistic carcinogenesis, tra deoxy LS178Y murine leukemia cells chea, mouse, 4301 3-Deazauridine 5-Azacytidine, 4000 Chediak-Higashi syndrome p-Chloromercuriphenylsulfonic acid D-Glucopyranose, 2-(3-(2- Leukemia, myeloblastic see Sulfonic acid, p- chloroethyl)-3-nitrosoureido)- Cell inclusions, 4473 chloromercuriphenyl- Metabolism, 3950 Macrophages Melamine, hexamethyl- Animal model, beige mouse Chlorozotocin Melamine, pentamethyl-, 4489 3934 See also D-Glucopyranose, 2-(3-(2- chloroethyl)-3-nitrosoureido)-deoxy- 833K-E testicular tumor cells Chemiluminescence Chromatin, binding, 3697 Germ cell tumor Carcinogenic metabolites, 2002 Morphological/ultrastructural/ Packard liquid scintillation spec L1210 cells trometer, 2002 DNA repair, 50 antigenic characteristics, 2500 Proteinase K, 50 833K-LC lymphoblastoid cells Chemotherapy DNA synthesis Germ cell tumor Drug exposure in vitro vs in vivo Cholanthrene, 3-methyl- Morphological/ultrastructural/ 2209 Acetamide, N-fluoren-2-yl- antigenic characteristics, 2500 Tumor cells vs normal bone mar Liver microsomes, hamster/rat 8387 fibrosarcoma cells row cells, 2709 3540 Fibronectin Hepatoma(s) Aryl hydrocarbon hydroxylase CCL 137 lung fibroblast cells Epinephrine, -r81 Carcinogenic metabolites, 424 4722 Norepinephrine, 481 Arylamide N-hydroxylase Hyperthermia Liver microsomes, hamster/rat 9L brain tumor cells Preclinical evaluation, dog, 253 3540 Methotrexate Macromomycin Epoxide hydrolase Dose-response culture, 3202 Letter to the editor, 1764 Lymphocytes, fresh/mitogen- Phosphorothioic acid, S-2-(3- Nitrogen mustard stimulated, 2552 DNA damage, 3186 aminopropylamino)ethyl- Ornithine, DL-a-methyl- Fibrosarcoma(s) Toxicity resistance, 1519 Radioresistance, mouse, 2547 Polyamines, 1961 Pyrazole, 2,3-dihydro-l//-imido[ 1,2-6]- X-rays, 2547 Uracil, 5-fluoro- azo- Dose-response culture, 3202 Pharmacokinetics, mouse, 1103 Urea, l,3-bis(2-chloroethyl)-l- Cholesterol nitroso- Chemotherapy, combination Cytosine, 1-/3-D-arabinofuranosyl- Leukemia L1210 DNA damage, 3186 Antitumor activity, mouse, 630 Circadian bioperiodic response, Liposome encapsulation, 630 Cellulose mouse, 1511 Mevalonic acid Colonie neoplasms Chlorambucil Hepatoma(s), 4717 Tumor incidence/histopathology, see Butyric acid, 4-[p-bis(2- rat, 2661 chloroethyl)aminophenyl]- Choline Central nervous system neoplasms Chlorine Barbituric acid, 5-ethyl-5-phenyl- L-Aspartate, JV-(phosphonacetyl)- Ion concentration Hepatocarcinogenesis, rat, 3846 Cerebrospinal fluid levels, human Cell transformation, neoplastic y-Glutamyltranspeptidase patients, 3163 1493 Hepatocarcinogenesis, rat, 3846 Cervix neoplasms Mitogenesis, 1493 Oncogenesis, 1493 Chondrosarcoma Drug therapy l-(2-Chloroethyl)-3-cyclohexyl-l- Neoplasm transplantation Animal model, nude mouse, 4287 2,6,10,14-Tetramethylpentadecane 4,4'-Stilbenediol, a,a-diethyl- nitrosourea 2229 Ultrastructural/morphometric see Urea, l-(2-chloroethyl)-3- study, 1558 cyclohexyl-1-nitroso- Choriocarcinoma Virus, herpes simplex 1 Gonadotropins, chorionic l-(2-Chloroethyl)-3-(2,6-dioxo-3- Adenosine cyclic 3':5'- Antibodies, neoplasm, 4640 piperidylM-nitrosourea Antibodies, viral, 4640 see Urea, l-(2-chloroethyl)-3-(2,6- monophosphate, 4025 Virus, herpes simplex 2 dioxo-3-piperidyl)-l-nitroso- Dibutyryl cyclic AMP, 4025 Antibodies, neoplasm, 4640 Lactate dehydrogenase-Z Antibodies, viral, 4640 BeWo cells, 3408 l-(2-Chloroethyl)-3-d-(5-p-nitroben- OMEGA-Z cells, 3408 Cesalin zoyl-2',3'-isopropylidene)-a,/3-D- Isoenzyme, trophoblast cell, 283 RNA synthesis rihofuraiiosvD-1-nitrosourea Cytotoxicity assay, mammalian see Urea, l-(2-chloroethyl)-3-(l '-(5'-p- Chromium cells, 225 nitrobenzoyl-2',3'-isopropylidene)- DNA synthesis Ultrastructural changes, 225 o,/)-D-ribofuranosyl)-l-nitroso- DNA polymerase, 2455

4888 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Chromosome aberrations Clofibrate Colonie neoplasms (cont'd) Benz(a)anthracene, 7,12-dimethyl- see Hypolipidemic peroxisome prolif- LS174T cells Thymectomized/intact/Freund'sLymphoma(s), 2609 erators Genetic signature analysis, 1443 Coenzyme A reducÃase,3-hydroxy-3- LSI80 cells adjuvant-fed mouse, 2609 Chromosome translocations methylglutaryl Bone marrow neoplasms 1443 Mevalonic acid Therapy-induced malignancy Genetic signature analysis, 1443 Hepatoma(s), 4717 4076 Citrobacter freundii Breast neoplasms Coenzyme Q,0 Hydrazine, 1,2-dimethyl-, 4451 Therapy-induced malignancy Mitomycin C Dietary fat 4076 Membrane potential difference, Acetamide, JV-fluoren-2-yl-, 2802 Cell transformation, viral liver, rat, 1663 Aflatoxin Bâ€ž2802 NL2/NL3/NL4 lymphoblastoid Potassium, 1663 Hydrazine, 1,2-dimethyl-, 2802 cells, 4775 Uracil, 5-fluoro Dietary fiber Leukemia Membrane potential difference, Tumor incidence/histopathology, Meeting report, 4826 liver, rat, 1663 rat, 2661 Lymphoma(s) Potassium, 1663 Dietary lipotropes Drug therapy, 4786 Acetamide, JV-fluoren-2-yl-, 2802 Colchicine X-rays, 4786 Aflatoxin Bâ€ž2802 Ovarian neoplasms Mammary neoplasms Hydrazine, 1,2-dimethyl-, 2802 Cell transformation, neoplastic Karyotyping, 4512 Doxorubicin 2383 L-Phenylalanine mustard Derivatives, 4682 Therapy-induced malignancy Collagen Hydrazine, 1,2-dimethyl- 4076 Attachment properties Immune response, mouse, 2475 Sezary syndrome, 3426 Metastatic vs nonmetastatic cells, a-Tocopherol, 1329 12-O-Tetradecanoylphorbol-13- mouse, 347 Tumor incidence/histopathology, acetate Endothelium rat, 2661 CHO cells, 3245 Spheroid attachment, 4631 V79 cells, 3245 Isoproterenol Fibronectin Adenosine cyclic 3':5'- X-rays Metastatic vs nonmetastatic cells, Fibroblasts, 920 mouse, 347 monophosphate, 2529 Radiosensitivity, 920 Neoplastic cells Lithocholic acid Chromosome, Philadelphia Extracellular matrix digestion L1210 cells, 2666 Hematopoietic stem cells 3222 DNA repair, 2666 MÃ©tastases Near haploid karyotype, 1354 Collagenase CT26 carcinoma cells, 2142 Leukemia, myelocytic Mammary neoplasms CT36 carcinoma cells, 2142 Near haploid karyotype, 1354 Cell transformation, neoplastic CT51 carcinoma cells, 2142 2383 Chromosome translocations Growth characteristics/ Procollagen LSI80 cells tumorigenicity, mouse cell lines CCL 137 lung fibroblast cells Colonie neoplasms, 1443 2142 4722 Chrysene Methane, azoxy- Papilloma(s) Colonie neoplasms Resection, intestinal, rat, 538 Mouse, 1981 Adenocarcinoma(s) Mitomycin C Skin neoplasms Blastogenesis inhibition factor, 29 Cell cycle kinetics, 1973 Dihydrodiols/diol-epoxides, 1981 LS174T cells, 1443 DNA now, 1973 LSI80 cells, 1443 Norepinephrine Chrysene, 5-methyl- Antibodies, monoclonal Adenocarcinoma(s), 4320 12-O-Tetradecanoylphorbol-13- Tumor-growth inhibition, mouse Platinum(II), c/s-dichlorodiammine- acetate 717 Hyperthermia, 1165 Carcinogenic activity, mouse skin Antibody-dependent cell-mediated Prostaglandins E Adenosine cyclic 3':5'- 1396 cytotoxicity Dihydrodiols, 1396 Tumor-growth inhibition, mouse monophosphate, 2529 Chymostatin 717 Proteins, nuclear MÃ©tastases Antigens, neoplasm Hydrazine, 1,2-dimethyl-, 1774 Hepatoma(s), 2539 Tumor-growth inhibition, mouse W-Pyrazolo(3,4-d)pyrimidin-4-ol Lung neoplasms, 2539 717 Tumor growth inhibition, mouse Carcinoembryonic antigen 1885 Cirrhosis Theophylline, 4744 Secretin Adriamycin Uridine, bromodexoy-, 4744 Adenosine cyclic 3':5'- Plasma drug levels, 1263 Cell transformation, neoplastic monophosphate, 2529 Adriamycinol Hydrazine, 1,2-dimethyl-, 1774 Sialyltransferase Plasma drug levels, 1263 HT29 cells Tumor burden, diagnosis, 1300 Citrobacter freundii Uracil, 5-fluoro-, 1574 /3-Sitosterol Hydrazine, 1,2-dimethyl- LoVo cells Anticarcinogenic activity, rat Carcinogenesis, colon, mouse Tumor growth kinetics, athymic 403 4451 mouse, 2846 Diet, vegetarian, 403

DECEMBER 1980 4889 Subject Index to Volume 40

Colonie neoplasms (cont'd) Cyanic acid, sodium salt (cont'd) Cyclophosphamide (cont'd) Urea, AT-methyl-TV-nitroso-, 403 Benzo(a)pyrene, 7,12-dimethyl- Plasmacytoma Thymidine Chemical carcinogenesis inhibitor, Dose schedule, mouse, 2135 Antitumor activity, rat, 1274 rat/mouse, 232 Immune response, mouse, 2135 Cytidine, deoxy-, 1274 Sulfhydryl derivatives, monomeric/ Cytosine, 1-/3-D-arabinofuranosyl- Cycloheximide Xanthine, l-methyl-3-isobutyl- polymeric 1274 Hydrolysis vs antitumor activity, Cytosine, 1-/3-D-arabinofuranosyl- Monocytes, 1955 S'-tri-phosphate, 1274 mouse, 2263 Cyclopenta[a]phenanthren-17-one, 15,- Toxicity, mouse, 2263 Toxicity, rat, 1274 16-dihydrn-II-methyl- Sulfido derivatives Uracil, 5-fluoro- Ames test Cytotoxicity, 4216 Gastrointestinal absorption, hu Carcinogenic and mutagenic man, 3400 metabolites, 882 Cys-dopa Vasoactive intestinal peptide Microsomal activation, 882 see Phenylalanine, 5-S-cysteinyl-L- Adenosine cyclic 3':5'- 3,4-dihydroxy- monophosphate, 2529 Cyclopenta(c,d)pyrene Structurally-related compounds Cystadenoma, mucinous Colony-stimulating factor Hyperthermia Ames test, 642 HL-60 cells Case report, 256 Colony formation, 1858 Methotrexate, 256 KG-1 cells Cyclophosphamide Thermal infusion filtration system Carcinosarcoma, Walker 256 256 Colony formation, 1858 L-Phenylalanine mustard, 830 Ml mouse myeloid leukemia cells Thiotepa, 256 MOPC 104E myeloma cells Cell differentiation, 4804 IgM, 2372 5-S-Cysteinyl-L-3,4- Complementation groups Plateau phase, mouse, 2372 dihydroxyphenylalanine Xeroderma pigmentosum Chemiluminescence see Phenylalanine, 5-S-cysteinyl-L- Epidemiological study, Egypt, 13 Carcinogenic metabolites, 2002 3,4-dihydroxy- Fibrosarcoma(s) Cytidine, 5-aza Concanavalin A Histological changes, mouse, 395 Adenocarcinoma(s) C3H/10T1/2 cells Immune response, mouse, 2756 Solid vs ascites form, rat, 1873 Mezereine, 334 Mechanism of action, 395 12-O-Tetradecanoylphorbol-13- Agarose bead complex 4-Hydroxycyclophosphamide- Transformed cell identification acetate, 334 4663 aldophosphamide Tumor promoters, 334 Carcinogens, chemical Cytotoxic metabolites, blood, Tumor promotion inhibitors, 334 mouse, 174 Bladder, mouse, 2006 Cytidine, deoxy- Screening, 2006 Leukemia L1210 Adenine, 9-ÃŸ-D-arabinofuranosyl- Diphtheria toxin Circadian bioperiodic response, mouse, 1511 Cytotoxicity, 1405 Tumor-specific chemotherapeutic DNA synthesis, 1405 agents, 3564 Sulfnydryl derivatives, 3704 Tumorigenicity/toxicity, mouse Colonie neoplasms Cortisol 3704 Thymidine, 1274 see Hydrocortisone Leukemia(s) Thymidine Intracellular incorporation, 1525 Corynebacterium pun urn Combination therapy, mouse Killer cells 4428 Cytidine dialdehyde Cell-mediated cytotoxicity, mouse Dose schedule, mouse, 2135 Leukemia L1210 4159 Immunotherapy, 4428 Antitumor activity, mouse, 598 Lymphoma(s), 4159 Leukocytes DNA synthesis, 598 Retinyl palmitate Mechanism of action, 395 Cytidine, 5-methyl- Antitumor activity, mouse, 4617 Lung neoplasms 5-Azacytidine Sulfhydryl derivatives, 3704 Lung neoplasms, 4617 Liver, rat, in vivo/in vitro, 2701 Tumorigenicity/toxicity, mouse Cryopreservation 3704 Cytidine, 5'-triphosphate, deoxy- Lymphoma(s) Macrophages Thymidine Immunological typing, tumor Mechanism of action, 395 CCRF-CM cells, 1718 cells, 2890 Mammary neoplasms Cytidylic acid, poly(2'-O-methyl-) CTP synthetase Cell kinetic recovery, rat, 737 DNA polymerases Microsomes, liver, mouse Hepatoma(s) Spleen, leukemia/lymphoma pa Normal/neoplastic/regenerating Drug sensitivity assay, 4443 tients, 1014 tissue, rat/human, 3921 Neoplasm growth Kidney neoplasms 3924A hepatoma cells, 2179 Cytochalasin B Normal/neoplastic/regenerating Computerized measurement Mammary neoplasms tissue, rat/human, 3921 2179 Cell transformation, neoplastic L-Phenylalanine mustard 2383 Cyanic acid, sodium salt Chromosome count, rodent tu Multinucleation Benz(a)anthracene, 7,12-dimethyl- mors, 830 Preneoplastic vs neoplastic mam Chemical carcinogenesis inhibitor, Cross-resistance, rodent tumors mary cells, 329 rat/mouse, 232 830 Virus, Kirsten murine leukemia

4890 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Cytochalasin B (cont'd) Cytosine, l-ÃŸ-D-arabinofuranosyl-(cont'd) Daunorubicin (cont'd) Tumorigenicity/soft agar cell Cytosine, 1-0-D- type cells, 1077 arabinofuranosyl-, 5'- growth, 4410 Ehrlich ascites tumor, 1077 Virus, Kirsten murine sarcoma triphosphate, 3286 Leukemia, AKR Tumorigenicity/soft agar cell Immunosuppression Dose scheduling, mouse, 2835 growth, 4410 Immune response, mouse, 3491 Sodium azide Virus, Moloney murine leukemia Leukemia P388 Pharmacokinetics, mouse, 1928 Tumorigenicity/soft agar cell MÃ©tastases,4758 Temperature growth, 4410 Leukemia(s) Pharmacokinetics, mouse, 1928 Virus, Moloney murine sarcoma Drug uptake/metabolism, bone Daunorubicin, Vncct> I- Tumorigenicity/soft agar cell marrow/peripheral blood cells growth, 4410 2441 Daunorubicin Virus, Rous sarcoma Undine, tetrahydro-, 2441 Drug resistance, tumor vs wild- Tumorigenicity/soft agar cell Thymidine type cells, 1077 growth, 4410 L1210 leukemia cells, 1525 Ehrlich ascites tumor, 1077 Cytochrome P-450 Cytotoxicity enhancement, 1525 Daunorubicin, V.Vdimcthv I- Acetamide-N-fluoren-2-yl- Intracellular incorporation, 1525 P388 cells Urea, hydroxy- Catalysis, NVring-hydroxylation Pharmacokinetics, mouse, 1928 L1210 leukemia cells, 3286 4456 Sodium azide Mouse, in vivo/in vitro, 3286 Antibody specificity Pharmacokinetics, mouse, 1928 Liver microsomes, 1652 Cytosine, l-ÃŸ-D-arabinofuranosyl-,5'- Deacylase Barbituric acid, 5-ethyl-5-phenyl- monophosphate Hydroxylamines, JV-acyl-N-2- Precancerous conditions, liver, rat WI-38 cells fluorenyl- 1658 Sialyltransferases, 1940 Ames test, 1204 Benzo(a)pyrene Sialic acid Enzyme activity, liver, guinea pig Reduction of epoxide derivatives WI-38 cells, 1940 1204 3-Deazauridine 2910 Sialoglycoproteins 5-Azacytidine Carcinogens, chemical WI-38 cells, 1940 Metabolic activation, 1652 Sialyltransferases, 1940 L5178Y murine leukemia cells 4000 Griseofulvin Cytosine, 1-ÃŸ-D-arabinofuranosyI-,5'- Hyperplastic liver nodules, mouse Synergistic Cytotoxicity, 4000 triphosphate Decano, 2,6,10.14-tetramethylpcnta- 2568 WI-38 cells Monooxygenase sec Pentadecane, 2,6,10,14-ietra- Sialyltransferases, 1940 methyl- Hormone regulation, 2486 Cytosine, 1-/8-D-arabinofuranosyl- 5H-Pyrido(4,3-b)indole, 3-amino-1,4- Dehydroepiandrosterone dimethyl- Deoxycytidine kinase, 3286 Androst-5-ene-3/3,170-diol Liver microsomes, rat, 2596 Leukemia, myeloblastic, 588 Radioimmunoassay, human breast 5H-Pyrido(4,3-b)indole, 3-amino-1- Ribonucleotide reducÃase Molt-4F lymphoblast cells, 3555 cytosol, 3815 methyl- Breast neoplasms Sialic acid Liver microsomes, rat, 2596 WI-38 cells, 1940 Radioimmunoassay, human breast Tryptophan cytosol, 3815 Sialoglycoproteins Liver microsomes, rat, 2596 WI-38 cells, 1940 4'-Demethylepipodophylloto\in-9-<4,6- 0-2-thenylidene-/3-D-glucopyranoside) Cytogenetics Cytosine-5-methyltransferase PC-3 cells see Epipodophyllotoxin, 4'- 5-Azacytidine Hyperdiploidy, 524 demethyl-, 9-(4,6-O-2-thenylidene- Liver, rat, in vivo/in vitro, 2701 Prostate neoplasms ÃŸ-D-glucopyranoside) RNA, transfer, 2701 PC-5-PI cells, 524 l-(2'-Deoxy-/3-D- Daunomycin Cytosine, l-/3-D-arabinofuranosyl- glucopyranosyDthymine Anemia Amphotericin B see Thymine, l-(2'-deoxy-/J-D- Bone marrow/spleen, mouse Antitumor activity, mouse, 1351 glucopyranosyl)- 2257 Drug entrapment, 1351 Erythrocytes LI210 leukemia cells Deoxyadenosine triphosphate Epipodophyllotoxin, 4'-de- Drug entrapment, 1351 Ribonucleotide reducÃase methyl-, 9-(4,6-O-2- thenylidene- Leukemia L1210 cells Molt-4F lymphoblast cells, 3555 Drug entrapment, 1351 ÃŸ-D-glucopyranoside) 4225 Deoxycoformycin Cholesterol Daunorubicin Adenine, 9-/3-D-arabinofuranosyl- Antitumor activity, mouse, 630 Adriamycin CCRF-CEM lymphoblastoid cells Liposome encapsulation, 630 Cardiotoxicity, mechanism, 4581 2349 Colonie neoplasms C3H/10T1/2 CL8 mouse fibro- DNA synthesis, 2349 Thymidine, 1274 Adenine, 9-/3-D-arabinofuranosyl-2- Cytosine, l-/3-D-arabinofuranosyl-, 5'- blast cells, 4581 AKR leukemia cells fluoro- triphosphate Cytotoxicity, 2835 CCRF-CEM lymphoblastoid cells Antineoplastic metabolite, 588 P388 cells 2349 Leukemia, myeloblastic, 588 Pharmacokinetics, mouse, 1928 DNA synthesis, 2349 Deoxycytidine kinase Daunorubicin, JV-acetyl- Deoxycytidine kinase L1210 leukemia cells, 3286 Drug resistance, tumor vs wild- L1210 leukemia cells

DECEMBER 1980 4891 Subject Index to Volume 40

Deoxycytidine kinase (cont'd) a's-Diamminedichloroplatinum(II) Dietary fats (cont'd) 9-/3-D-Arabinofuranosyl-2- See Platinum(II), diamminedichloro-, Carcinogenesis, liver, rat, 2802 fluoroadenine, 3610 cis Benz(a)anthracene, 7,12-dimethyl- Cy tosine, 1-ÃŸ-arabinofuranosyl- Dibenz(a,c)anthracene Carcinogenesis, mouse, 2785 L1210 leukemia cells, 3286 Papilloma(s) Mammary neoplasms, 2785 Cytosine, 1-/3-arabinofuranosyl-, Hydrazine, 1,2-dimethyl- 5'-triphosphate, 3286 Mouse, 1981 Skin neoplasms Carcinogenesis, liver, rat, 2802 Deoxynucleosides Dihydrodiols/diol-epoxides, 1981 Mammary neoplasms Lymphocytes, null-type Prolactin, 374 S'-Ribonucleotide phosphohydro- Dibenz(a,h)anthracene Papilloma(s) lase, 3383 Mouse, 1981 Dietary fiber Deoxynucleotidyl transferase Skin neoplasms Colonie neoplasms Leukemia, acute undifferentiated Dihydrodiols/diol-epoxides, 1981 Tumor incidence/histopathology, Lymphoblasts, 4048 rat, 2661 Dibenzo(a,e)fluoranthene Leukemia, myelocytic Liver microsomes, rat/mouse Lymphoblasts, 4048 Bay region epoxides, 1742 Dietary lipotropes Spleen, leukemia/lymphoma patients Carcinogenic metabolites, 1742 Acetamide, JV-fluoren-2-yl- 1014 Dibenzo-p-dioxin, 2,3,7,8-tetrachloro- Carcinogenesis, liver, rat, 2802 Aflatoxin B, Deoxyribonucleoside triphosphates Benzo(a)pyrene Testis, rat, in vitro, 3297 Carcinogenesis, liver, rat, 2802 Purine nucleotides Hydrazine, 1,2-dimethyl- Normal/regenerating/neoplastic/ Carcinogens, chemical Carcinogenesis, liver, rat, 2802 neonatal liver, rat, 1286 Anticarcinogenic activity, female Pyrimidine nucleotides mouse, 1580 Chlorinated hydrocarbon deriva Normal/regenerating/neoplastic/ Diethylamine, .V-nitroso- neonatal liver, rat, 1286 tives, 1580 Metabolic activation, 1580 Acetamide, JV-fluoren-2-yl Deoxyuridine triphnsphate diphosphory- Skin neoplasms, 1580 Liver neoplasms, 1112 lase Diethylamine, AT-nitroso- Preneoplastic hepatocytes, rat Uracil, 5-fluoro- Hepatocarcinogenesis, rat, 3616 1112 DNA, 998 Barbituric acid, 5-ethyl-5-phenyl- Lymphocytes, human, 998 Dibutyryl cyclic AMP Hepatocarcinogenesis, rat, 4261 Cell differentiation Dibenzo-p-dioxin, 2,3,7,8- Dexamethasone Ml myeloid leukemia cells, 3387 tetrachloro- Breast neoplasms HeLa-S3 cells Hepatocarcinogenesis, rat, 3616 Epidermal growth factor, 2361 Neocarzinostatin, 3786 Glutathione Butyrophenone, 4-(4-(p- Gonadotropins, chorionic Hyperplastic cell islands, liver, rat chlorophenyl)-4- CBT brain tumor cells, 4325 490 Prolactin, 1863 TPA30-1 transformed placenta! Microsomal oxidative dealkylation Tumor growth inhibition, rat cells, 4025 Aldehyde assay, 3241 1863 Trophoblastic/nontrophoblastic Oral contraceptives Cell differentiation cells, 4519 Hepatocarcinogenesis, rat, 3680 Ml myeloid leukemia cells, 3387 Choriocarcinoma, 4025 Mammary neoplasms Glioblastoma multiforme, 4325 Butyrophenone, 4-[4-(p-chloro- Diethylnitrosame see Diethylamine, AT-nitroso- phenyl)-4-hydroxypiperidino]4 ' - 1,2-Dichloroethane fluoro- see Ethane, 1,2-dichloro- Plasminogen activator Diethylstilbestrol see also 4,4'-Stilbenediol, a,a- Neoplastic cells/embryonic cells Diet diethyl- 2706 Carcinoma, Ehrlich tumor Genital tract Receptors, hormone Fatty acids, 4606 Transplacental carcinogenisis, Clonal proliferation, 563 Sarcoma(s) Leukemia, myeloblastic, 563 Body composition vs tumor mouse, 3988 X-rays growth, adult mouse, 2516 Diabetes Mammary neoplasms, 3966 Benz(a)anthracene, 7,12-dimethyl- Diet, vegetarian Synergistic Carcinogenesis, rat Mammary neoplasms, 2343 3966 Receptors, hormone, 2343 Colonie neoplasms /3-Sitosterol, 403 4,4'-Diacetyl-diphenylurea- 2,3-Dihydro-lH-imidazo[l,2-Â¿]pyrazole bis(guanylhydrazone) Dietary fats see Pyrazole, 2,3-dihydro-lH-imido Acetamide, Ar-fluoren-2-yl- see Guanidine [l,2-o]-,azo- Carcinogenesis, liver, rat, 2802 Diamine oxidase Adenocarcinoma(s) Carcinoma, epidermoid Immune response, mouse, 3745 15,16-Dihydro-ll-methylcycIopenta L-Dopa decarboxylase, 1990 Tumor growth, in vitro, mouse [a]phenanthren-17-one Carcinoma, small cell 3745 see Cyclopenta[a]phenanthren-17- L-Dopa decarboxylase, 1990 Aflatoxin B, one, 15,16-dihydro-ll-methyl-

4892 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

2,3-Dihydro-LH-pyrazolo(2,3-/l)imida- Dipropylamine, 2,2'-dioxo-JV-nitroso- DNA adducts (cont'd) zole Ames test Radioimmunoassay quantitation, see lif-Pyrazolo(2,3-A)imidazole, 2, Aryl hydrocarbon hydroxylase epidermal cells, 412 3-dihydro- 67 Carcinogenic metabolites, hamster DNA damage 9L brain tumor cells 67 Dihydrofolate reducÃase Nitrogen mustard, 3186 Methotrexate V79 hamster liver cells, 3463 N-Nitrosobis(2-oxopropyl)amine Nuclease assay, 3186 Tissue drug levels, 1230 Urea, l,3-bis(2-chloroethyl)-l- 67 nitroso-, 3186 Pancreatic neoplasms Trajis-4,5-dihydroxy-4,5- Hepatocytes, rat Adenocarcinoma(s), 67 Collagen gel-nylon mesh culture dihydrobenzo(a)pyrene Carcinogenicity, hamster, Syrian see Benzo(a)pyrene, trans-4,5- 3259 dihydro-4,5-dihydroxy- 3585 DNA, double-stranded Diterpene esters Chick embryo fibroblasts Melanoma(s) AyV-Dimethyl-4-aminoazobenzene Isolation and characterization see Azobenzene, JV,.iV-dimethyl-4- Inflammatory activity, 339 Structure-activity relationships 3792 amino- 339 DNA methylase Guanidine, JV-methyl-N'-nitro-./V- Dimethylamine, .V-nitrosn- Dithiothreitol DNA methylase nitroso- Aflatoxin B Guanidine, Ar-methyl-Ar-nitro-JV- Acetamide, iodo-, 61 Synergistic carcinogenesis, rat nitroso-, 61 Dithiothreitol, 61 4037 DNA DNA DNA, PM-2 Acetamide, Ar-fluoren-2-yl- LiverAidney, human, 3116 Platinum(II), diamminedichloro-, cis Hepatocarcinogenesis, rat, 1269 Purines, 3116 Binding/conformational changes Microsomal oxidative dealkylation Aflatoxin B, Adduci formation vs colony-cell 3313, 3318 Aldehyde assay, 3241 Second-generation platinum ana viability, 2904 logs, 3318 7,12-DimethyIbenzanthracenc 10T1/2 mouse embryo cells see Benz(a)anthracene, 7,12- 2904 DNA polymerase dimethyl- Azobenzene, JV-benzoyloxy-Ar- Alanine, 3-(3,4-dihydroxyphenyl)-, L- methyl-4-amino- Tyrosinase, 1414 1,2-Dimethylhydrazine Adduct formation, in vitro, 2493 Arsenic see Hydrazine, 1,2-dimethyl Azobenzene, N,JV-dimethyl-4-amino- DNA synthesis, 2455 Adduct formation, in vitro, 2493 Breast neoplasms Dimethylnitrosamine Azobenzene, Ã•V-methyl- see Dimethylamine, JV-nitroso- Cells, human, 3880 Adduct formation, in vitro, 2493 Butyrophenone, 4-[4-(p- Benzo(a)pyrene chlorophenyl)-4- 2,6-Dimethylnitrosomorpholine Near-ultraviolet light, 245 hydroxypiperidino]-4'-fluoro- see Morpholine, 2,6-dimethyl-Ar- Bleomycin Tyresinase, 1414 nitroso- Nicotinamide adenine dinucleo- A-374 melanoma cells tide phosphate, 2051 Tissue distribution, normal/ 2,4-Dinitrophenol Carcinogens, chemical neoplastic, human, 4398 see Phenol, 2,4-dinitro- Gene expression, 3374 Chromium Dimethylamine, N-nitroso- DNA synthesis, 2455 Dinitrosopiperazine Liver/kidney, human, 3116 Cytidylic acid, poly(2'-O-methyl-) see Piperazine, 1,4-dinitroso- Purines, 3116 Spleen, leukemia/lymphoma pa 170-Estradiol tients, 1014 Dipeptidyl hydrolase angiotensin- Receptors, hormone, 1050 170-Estradiol converting enzyme Guanosine, deoxy- Antiestrogens, 1722 Bleomycin Adduct formation, in vitro, 2493 Leukemia, MCDV-12 ascitic Animal model, rat, 3621 Purine-6-thiol Inhibition factor, mouse, 758 Bacillus subtilis, 4381 Myeloma, MOPC-21 Diphtheria toxin Transforming activity, 4381 Inhibition factor, mouse, 758 Antibody targeting 6-Thioguanine Receptors, hormone Tumor-specific chemotherapeutic Bacillus subtilis, 4381 MCF-7 cells, 1722 agents, 3564 Transforming activity, 4381 Selenium Concanavalin A Uracil, 5-fluoro- DNA synthesis, 2455 Tumor-specific chemotherapeutic Deoxyuridine triphosphate di- DNA repair agents, 3564 phosphorylase, 998 Uracil-DNA glycosylase, 998 Chlorozotocin, 50 Dipropylamine, 2,2'-dihydroxy-JV- Urea, 7V-ethyl-JV-nitroso- Lithocholic acid, 2666 887 Aflatoxin B, nitroso- Intestinal mucosa cells, human Ames test DNA adducts 3155 V79 hamster liver cells, 3463 Benzo(a)pyrene Aflatoxins, 3719

DECEMBER 1980 4893 Subject Index to Volume 40

DNA repair (cont'd) DNA repair (cont'd) DNA synthesis (cont'd) Angelicin Age, sex, diet factors, rat, 3719 Antineoplastic analogs, human/ Photoactivation, 696 Fibroblast cell cultures, controls/ mouse cells, 1414 WI-38 fibroblast cells, 696 patients, 2736 Melanoma(s), 1414 Xeroderma pigmentosum cells Methanesulfonic acid, methyl es Chemotherapy 696 ter, 582 Drug exposure in vitro vs in vivo Antineoplastic agents Postreplication repair, mouse 2209 Caffeine, 1332 1867 Tumor cells vs normal bone mar Ataxia telangiectasia Skin, human, 3181 row cells, 2209 Guanidine, /V-methyl-JV-nitro-./V- X-rays, 582 Chromium nitroso-, 984 Xeroderma pigmentosum, 2736 DNA polymerase, 2455 Methanesulfonic acid, methyl es Xeroderma pigmentosum Cytidine dialdehyde ter, 984 Antigens, viral, 3945 Leukemia L1210, 598 Ultraviolet rays, 984 EpidemiolÃ³gica! study, Egypt, 13 Enzymatic activity Chinese hamster ovary cells DNA replication Normal/neoplastic/fetal, human/ Urea, N-ethyl-AT-nitroso-, 2623 Melanoma(s), 3792 rat liver, 1235 Urea, JV-methyl-JV-nitroso-, 2623 17ÃŸ-Estradiol CRL 1121/1221/1223 fibroblast cells Antiestrogens, 1722 Acetamide, JV-(acetyloxy)-JV-9-//- DNA, single-strand Guanidine, TV-methyl-JV'-nitro-JV- fluoren-2-yl, 4313 Bleomycin nitroso- Bacteriophage PM-2, 4173 C3H mouse embryo cells Intestinal mucosa cells, human HeLa S, cells Caffeine, 4415 3155 Neocarzinostatin, 2405 Cell cycle, 4415 Hepatocytes, rat Fluorescent light, 4415 L1210 cells Collagen gel-nylon mesh culture Lithocholic acid, 2666 EMT6 cells 3259 NHIK 3025 carcinoma cells Postreplication repair, mouse Hydrazine, 1,2-dimethyl- Hematoporphyrin, 2915 1867 X-rays, 2915 Carcinogenesis, colonie mucosa, HeLa S, cells rat, 4589 Selenium Neocarzinostatin, 2405 Hypolipidemic peroxisome prolifera- 2670 MLF cells tors Talisomycin Postreplication repair, mouse Bacteriophage PM-2, 4173 Ames test, 36 1867 L-Canavanine Diethylamine, JV-nitroso- Antitumor activity, mouse, 535 Hepatocarcinogenesis, rat, 4261 DNA synthesis L1210 cells, 535 Adenine, 9-/2-D-arabinofuranosyl- Guanidine, N-methyl-TV-nitro-N- Pancreatic neoplasms CCRF-CEM cells, 1405 nitroso- Cell transformation, neoplastic Cytidine, deoxy-, 1405 Intestinal mucosa cells, human 3443 3155 Deoxycoformycin, 2349 Radiation, non-ionizing L1210 cells Leukemia, lymphoblastic, 1405 Methotrexate, 1002 Urea, l,3-bis(cyclohexyl)-l- Adenine, 9-/3-D-arabinofuranosyl-2- Retinyl acetate nitroso-, 50 fluoro- Benz(a)anthracene, 7,12-dimethyl- Urea, l-(2-chloroethyl)-3- CCRF-CEM cells, 1405 1109 cyclohexyl-1 -nitroso-, 50 Deoxycoformycin, 2349 Rat, female Sprague-Dawley X-rays, 50 Leukemia, lymphoblastic, 1405 1109 Melanoma(s) Adenine, 9-/3-D-arabinofuranosyl-2- Urea, JV-methyl-JV-nitroso-, 1109 Postreplication repair, mouse Aflatoxin B, Selenium 1867 Intestinal mucosa cells, human DNA polymerase, 2455 8-Methoxypsoralen 3155 Sodium saccharin Photoactivation, 696 Photoactivation, 689 Promoting agent, 734 WI-3S lioroolast cells, o% Template activity, 689 12-O-Tetradecanoylphorbol-13- Xeroderma pigmentosum cells Alanine, 3-(3,4-dihydroxyphenyl)-, L- acetate 696 Antineoplastic analogs, human/ Lectin-stimulated lymphocytes, Nitrosoureas mouse cells, 1414 bovine, 3307 L1210 cells, 771 Melanoma(s), 1414 Thymidine Radiation, ionizing, 771 Alkylating agents Antitumor activity, 818 Nucleosides, 3719 C3H/1OT1/2 cells, 682 Partial hepatectomy, 1538 Pyrimidine dimers Chinese hamster V79 cells, 682 Assay techniques, 3181 Arsenic DNA viruses Selenium DNA polymerase, 2455 2670 Leukemia(s) Breast neoplasms Review, 3405 Trachea! neoplasms Carcinoma(s), 1890 Lymphoma(s) Carcinogenesis, rat, 2898 Butyric acid, 4-[p-bis(2- Review, 3405 Methanesulfonic acid, methyl es chloroethyl)aminophenyl]- ter, 2898 HeLa cells, 967 L-Dopa decarboxylase Quinoline, 4-nitro, 1-oxide, 2898 Butyrophenone, 4-[4-(p- Carcinoma, epidermoid Urea, N-ethyl-N-nitroso-, 2898 chlorophenyI)-4- Diamine oxidase, 1990 Ultraviolet rays hydroxypiperidino]-4'- fluoro- In vivo vs in vitro activity, 1990

4894 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

L-Oopa decarboxylase (cont'd) Elastin Epithelium (cont'd) Carcinoma, small cell Neoplastic cells Morphological/biochemical cha Diamine oxidase, 1990 Extracellular matrix digestion racteristics, trachea, hamster In vivo vs in vitro activity, 1990 3222 4403 Dopamine Elastina! RL34 cells, 1318 see Butyrophenone, 4-[4-(p- MÃ©tastases Concanavalin A chlorophenyl)-4- Hepatoma(s), 2539 Screening, 2006 hydroxypiperidino]-4- fluoro- Lung neoplasms, 2539 Cytoplasmic organelles Protease inhibitors Pleomorphism, normal/ Doxorubicin Hepatoma(s), 2539 nonmalignant/malignant tis Derivatives sues, 803 Antitumor activity, 4682 Ellipticine Ultrastructural study, human Human tumor transplants, nude see 6//-Pyrido(4,3-f>)carbazole, 5,11- 803 mouse dimethyl- Ectocervix Antitumor activity, 4682 Endothelium Cell culture, 512 D-Valine medium, 512 Drug therapy Collagen Mammary neoplasms Antineoplastic agents Spheroid attachment, 4631 Anchorage independent/ Human solid tumor cells, 4438 Tumor spheroids dependent cells, 1812 Drug sensitivity assay, 4438 Spheroid attachment, 4631 Epithelial cell junctions, 1588 Breast neoplasms Ependymoblastoma Methanesulfonic acid, methyl ester Ovarian/adrenal gland function Hyperthermia Trachea, rat, 2898 4043 Urea, l-(2-chloroethyl)-3- Quinoline, 4-nitro, 1-oxide HeLa cells cyclohexyl-1-nitroso-, 2726 Trachea, rat, 2898 Animal model, nude mouse, 4287 Urea, N-ethyl-JV-nitroso- Ependymoma Cervix neoplasms Trachea, rat, 2898 Animal model, nude mouse, 4287 RNA synthesis Lymphoma(s) Urea, l-(2-chloroethyl)-3- cyclohexyl-1-nitroso-, 939 Somatic cell damage, children Epoxide hydrolase 4786 Epidermal growth factor Barbituric acid, 5-ethyl-5-phenyl- Review Breast neoplasms Lymphocytes, fresh/mitogen- Breast neoplasms, 4335 Dexamethasone, 2361 stimulated, 2552 Therapeutic index, 4335 Insulin, 2361 Benzo(a)anthracene MCF-7 breast cancer cells, 2361 Lymphocytes, fresh/mitogen- EC 2.4.2.1 MDA-231 breast cancer cells, 2361 stimulated, 2552 see Inosine phosphorylase Phagocytosis Cholanthrene, 3-methyl- EC 2.4.99.1 Macrophages, mouse, 1028 Lymphocytes, fresh/mitogen- see GlycoproteinrN-acetylneuraminic P388D, cells, 1028 stimulated, 2552 Flavone, /J-naphtho- acid transferase Epinephrine Lymphocytes, fresh/mitogen- EC 3.1.3.5 Hepatoma(s) see 5'-Ribonucleotide phosphohydro- Chemotherapy, 481 stimulated, 2552 Hormone regulation lase Hemodynamics, rat, 481 Epipodophyllotoxin, 4'-demethyl-, 9-(4,- Testis, hypophysectomized rat EC 3.6.1.23 2486 see Deoxyuridine triphosphate di- 6-O-2-1henvlideni'-/3-D- Normal/hyperplastic/neoplastic liver phosphorylase glucopyranoside) microsomes, rat, 2768 LI210 leukemia cells Pregnenolone-16a-carbonitrile EC 6.3.4.2. Cytosine, 1-0-D-arabinofuranosyl- Lymphocytes, fresh/mitogen- see CTP synthetase 4225 stimulated, 2552 Ecto-ATPase DNA, 4225 Smoking see Adenosine 5'-triphosphatase Synergistic effects, 4225 Lymphocytes, fresh/mitogen- Ecto-S'-nucleotidase Epithelium stimulated, 2552 f/ans-Stilbene oxide see 5'-Ribonucleotide phosphohydro- Basal lamina Lymphocytes, fresh/mitogen- lase Mammary neoplasms, 1600 Bladder neoplasms stimulated, 2552 Ectocervix Thiazole, 2-amino-4-(5-nitro-2- a-Ergocryptin, 2-bromo- Epithelium furyl)-, 1897 Urea, JV-methyl-N-nitroso- Cell culture, 512 Carcinogens, chemical D-Valine medium, 512 Carcinogenicity, rat, 3095 Screening, 2006 Cell culture Erythroblasts Ehrlich ascites tumor Virus, Friend murine leukemia see Carcinoma, Ehrlich tumor Preneoplastic cells, mouse, 3982 Cell proliferation Ultrastructural study, 1150 Virus, spleen focus-forming 5,8,1l,14-K,icosaU.'traynoicacid Liver factors, rat, 1249 12-O-TetradecanoylphorboI-13- Neoplastic vs nonneoplastic cell Ultrastructural study, 1150 acetate lines, 1249 Erythrocytes Lymphocytes, bovine, 776 Cell transformation, neoplastic Daunomycin Oxygen-dependent synthesis, 776 Epithelial cells, liver, 1318 Drug entrapment, 1351

DECEMBER 1980 4895 Subject Index to Volume 40

Erythroleukemia 17/3-Estradiol (cont'd) DL-Ethionine Ornithine decarboxylase Leydig cells see Butyric acid, 2-amino- Cell differentiation induction Carcinogenic effect, mouse, 1006 4-(ethylthio)-, DL- 1727 Receptors, hormone L-Ethionine Polyamines DNA, 1050 Cell differentiation induction Cell differentiation Mammary neoplasms, 1050 HL-60 leukemia cells, 3206 1727 Estradiol, lla-methoxyethinyl- Cell differentiation, 3369 Ethyl carbamate Mammary neoplasms Plasminogen activator, 3369 see Carbamic acid, ethyl ester Virus genonme expression, 3369 Receptors, hormone, 3232 Ethyl JV-hydroxycarbamate Estrogen Erythropoieses see Carbamic acid, hydroxy-, ethyl Adenosylmethionine decarboxylase Anemia ester Adriamycin, 2257 Sex factors, liver, rat, 620 Cytosine, l -ÃŸ-D-arabinofuranosyl- Antineoplastic agents 1-Ethyl-l-nitrosourea 2257 Receptors, hormone, 2941 see Urea, -/V-ethyl-N-nitroso- Benz(a)anthracene, 7,12-dimethyl- Escherichia coli Mammary neoplasms, 2343 Ethylamine, JV-methyl-A^nitroso- Asparaginase Breast neoplasms Deuterium labeling Glutaminase, 1125 Plaque-forming cell assay, 1125 Receptors, hormone, 3357 Carcinogenicity, rat, 19 Benzo(a)pyrene-7,8-dihydrodiol 9,10- Leydig cells Carcinogenic effect, mouse, 1006 O'-Ethyldeoxyguanosine oxide Lymphoma(s) see Guanosine, O'-ethyldeoxy- Mutagenicity vs cytotoxicity Pituitary gland, 2437 3508 Ethylene, chloro- Caffeine Mammary neoplasms Mutation, 1332 Enzyme activity, tumor/uterus, Ames test Methanesulfonic acid, ethyl ester rat, 3158 Liver microsomes, human/rat Glucose-6-phosphate dehydroge- Mutagenicity vs cytotoxicity 119 3508 nase, 3158 Benzo(a)pyrene hydroxylase Quinoline, 4-nitro, 1-oxide a-Glycerol phosphate dehydroge- Carcinogenic metabolites, 119 Mutagenicity vs cytotoxicity nase, 3158 Cytochrome P-450-dependent mo- 3508 Malic enzyme, 3158 nooxygenases Peroxidase, 3158 Intel-individual differences, 119 Esophageal neoplasms Progesterone, 3232 Ethylene, chloro- oxide Benzylamine, JV-methyl-N-nitroso- Prolactin, 3232 Carcinogenic metabolite, 352 Target tissues, 1921 Receptors, hormone, 235, 3232 Morpholine, JV-nitroso- Papilloma(s) Progesterone Carcinogenic metabolites, 119 Piperazine, N"-methyl-N-nitroso- Nitrosomethylethylamine deriva Mammary neoplasms, 1091 tives, 19 Prostatic neoplasms Carcinogenic metabolites, 119 Review Hormone dependency, rat, 3547 Epidemiology, China, 2633 3551 Sialyltransferase Ethylene, chloro-, oxide Receptors, hormone Tumor burden, diagnosis, 1300 Ethylene, chloro- Breast neoplasms, 2557 Carcinogenic metabolite, 352 Esthesioneuroblastoma Dextran-coated charcoal vs su 12-O-Tetradecanoylphorbol-13- see Neuroepithelioma crose gradient analyses, 4127 acetate Estrogen sulfotransferase, 1360 Carcinogenicity, mouse, 352 Estradici S-phase fractions, human, 1890 Antiestrogens tRNA, methyltransferases Receptors, hormone, 3821 Ethylenediaminetetraacetic acid Uterus, guinea pig, 3821 Sex factors, liver, rat, 620 Urea, JV-methyl-JV-nitroso- Carcinoma, Ehrlich ascites Mammary neoplasms Cell proliferation, in vitro, 4092 Glucose-6-phosphate dehydroge- Receptors, hormone, 235 DNA synthesis, 4092 nase, 3158 Estrogen sulfotransferase a-Glycerol phosphate dehydroge- Breast neoplasms nase, 3158 Receptors, hormone, 1360 D-factor Malic enzyme, 3158 Estrogen Ml mouse myeloid leukemia cells Peroxidase, 3158 Receptors, hormone, 1360 Cell differentiation, 4804 Nafoxidine Progesterone Receptors, hormone, 3821 Receptors, hormone, 1360 Fatty acids Tamoxifen Carcinoma, Ehrlich tumor Receptors, hormone, 3821 Ethane, 1,2-dichloro- Binding, lung microsomes, rat, 2170 Diet, 4606 17/3-Estradiol Metabolism, 2447 Binding, sperm DNA, salmon, 2170 Antiestrogens Synthesis, mouse, in vivo/in vitro Breast neoplasms, 1722 Ether, bis(chloromethyl) 4606 DNA polymerase, 1722 12-O-Tetradecanoylphorbol-13- Morris hepatoma 7777 cells Breast neoplasms acetate Complement-mediated cytolysis Receptors, hormone, 1750 Carcinogenicity, mouse, 352 1084

4896 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Fatty acids, polyunsaturated Fibrosarcoma(s) (cont'd) Follicle-stimulating hormone Ames test Attachment properties, 347 Aryl hydrocarbon hydroxylase Mutagenic metabolites, 276 Fibronectin, 347 Testis, hypophysectomized rat Cyclophosphamide 2486 Ferritin Histological changes, mouse, 395 Epoxide hydrase Neuroblastoma Immune response, mouse, 2756 Testis, hypophysectomized rat Disease activity, 1411 Mechanism of action, 395 2486 Serum level, humans, 1411 Hyperthermia Glutathione transferase Multifractionated treatment, Testis, hypophysectomized rat a-Fetoprotein mouse, 2045 2486 Oligosaccharides Hyperthermia, localized Formaldehyde Ascites fluid, human, 4282 Neoplasm transplantation, 26 Carcinoma, epidermoid Isolation and characterization Neoplasm mÃ©tastases Carcinogenesis, mouse/rat, 3398 4282 Immunological/nonimmunological Nasal cavity neoplasms RNA, messenger factors, mice, 625 Carcinogenesis, mouse/rat, 3398 Normal/hype rplastic/neoplastic Ultraviolet rays, 625 liver, rat, 3713 Neoplasm transplantation Formamide, JV-[4-(5-nitro-2-furyl)-2- Immunization, 1036 thiazolyl]- Fibroblasts Ultraviolet rays, 625 S-Adenosylmethionine decarboxylase Antigens, fetal Radiotherapy Enzyme activity, mouse, 1897 Complement-dependent cytotoxic Neoplasm transplantation, 26 Bladder neoplasms reactivity, sera, human, 979 Flavone, 5,6-benzo- Carcinogenic metabolites, rabbit/ X-rays p-Toluamide, JV-isopropyl-a-(2- ram, 114 Chromosome aberrations, 920 methylazo)- Ornithine decarboxylase, 1897 Clonogenic survival assay, 920 Tumor growth, rat, 4524 Liver microsomes, rat/rabbit Hereditary diseases, 920 Urine, 4524 3524 RBTCC carcinoma cells Metabolites, 3524 Fibroblasts, 3T3 Morphological characteristics/ Guanidine, 1. Flavone, /J-naphtho- tumorigenicity, 4571 1'-(methylethanediylidenedini- Epoxide hydrolase Mitomycin C trilo)di-, Lymphocytes, fresh/mitogen- Bladder neoplasms, 261 Polyamine growth regulation stimulated, 2552 Ornithine decarboxylase 293 Flavone, 3,3',4',5,7-pentahydroxy- Enzyme activity, mouse, 1897 Prostaglandin endoperoxide synthe- Spermidine, 293 Bracken fern tase Spermine, 293 Carcinogenicity, rat, 3468 Urea, hydroxy- Carcinogenic metabolites, rabbit/ Ehrlich ascites tumor cells Selective killing, 293 Adenosine cyclic 3':5'- ram, 114 Kidney microsomes, rabbit, 114 Virus, SV40 monophosphate, 1344 Seminal vesicle microsomes, ram Transformation, viral, 293 DNA synthesis, 1344 114 Lactic acid, 1344 I round's adjuvant Fibronectin Liposomes Arginine Growth inhibition, 1344 Antibody, antiidiotypic Cell transformation, neoplastic Fluoren-2-amine Immune response, mouse, 1630 MOPC 315 myeloma cells 2562 DNA, nuclear Cytotoxicity, 1630 Cell transformation, neoplastic Binding, hepatocytes, rat, 3579 Liver epithelial cells, mouse Protein, nuclear Ftorafur 2562 Binding, hepatocytes, rat, 3579 see Uracil, 5-fluoro-l-(tetrahydro-2- CCL 137 lung fibroblast cells furanyl)- Fibronectin-releasing activity N-2-Fluorenylacetamide 4722 see Acetamide, W-fluoren-2-yl-, 2802 Fucosyltransferase Leukemia, granulocytic 8387 fibrosarcoma cells Fluorescent light Enzyme activity, plasma, human CCL 137 lung fibroblast cells DNA repair 3576 4722 C3H mouse embryo cells, 4415 Collagen 5-Fluoro-2'-deoxyuridine Fusobacterium nucleatum Metastatic vs nonmetastatic cells, see Undine, 5-fluoro-2'-deoxy- P3HR-1 human lymphoblastoid cells mouse, 347 Antigen induction, 4329 5-Fluoro-2'-deoxyuridinc 5'- Fibrosarcoma(s) Antigens, viral, 4329 Antigens, neoplasm monophosphate Virus, Epstein-Barr, 4329 see Undine, 5-fluoro-2'-deoxy-, Immune response, rat, 2129 5'-monophosphate Galactoproteins Cell membrane potential AS-30D hepatocellular carcinoma Normal/neoplastic cells, rat/ 5-FluorouraciI cells mouse, 1830 see Uracil, 5-fluoro- Cholanthrene, 3-methyl- Isolation/characterization, 2853 Radioresistance, mouse, 2547 Folinic acid D-Galactosamine X-rays, 2547 Methotrexate 5-Azacytidine Collagen Immunosuppression, 650 Cytosine-5-methyltransferase

DECEMBER 1980 4897 Subject Index to Volume 40

D-Galactosamine (cont'd) Gluconeogenesis Glutathione (cont'd) Cytosine-5-methyltransferase Picolinic acid, 3-mercapto- L-Ascorbic acid 2701 Sarcoma(s), 1699 Bone marrow cells, human, in Liver, rat, in vivo/in vitro, 2701 Sarcoma(s) vitro, 1062 D-Galactose Tumor glucose demand, rat Diethylamine, N-nitroso- Hepatoma, Morris 1699 Hyperplastic cell islands, liver, rat Starvation, 1699 Metabolism, rat, 2026 490 D-Glucopyranose, 2-(3-(2-chloroethyl)- Morpholine, JV-nitroso- Gastrointestinal neoplasms 3-nitrosoureido)- Hyperplastic cell islands, liver, rat Carcinoembryonic antigen Antineoplastic agents 490 Tumor burden, diagnosis, 1300 Flavone, 3,3',4',5,7-pentahydroxy- Hematological toxicity, mouse Glutathione peroxidase 4282 Selenium Carcinogenicity, rat, 3468 L1210 leukemia cells Dietary deficiency, rat, 2670 Kaempferol Cytotoxicity, 3723 Carcinogenicity, rat, 3468 LI5178Y lymphoblast cells Glutathione transferases Benzo(a)pyrene, fra/is-4,5-dihydro- Sialyltransferase Metabolism, 3950 Carcinoembryonic antigen, 1300 4,5-dihydroxy- Tumor burden, diagnosis, 1300 Glucose Conjugated metabolites, perfused Ascites tumor cells lung, rabbit, 101 Gene expression Electrophoretic mobility, 4751 Benzo(a)pyrene 4,5-oxide Carcinogens, chemical HeLa cells Conjugated metabolites, perfused DNA, 3374 Hyperthermia, 3459 lung, rabbit, 101 Drosophila melanogaster, 3374 Hyperthermia Hormone regulation Genetics Tumor blood supply, rat, 4728 Testis, hypophysectomized rat 4-Methylphorbol-12,13-didecanoate Carcinogenesis, chemical 2486 Insulin, 3827 Peptide composition Susceptibility vs virus production, 12-O-Tetradecanoylphorbol-13- mouse, 4364 Isolation and characterization, liv Virus, xenotropic acetate er, hamster, 1787 Insulin, 3827 Susceptibility vs virus production, DL-Glycerol mouse, 4364 Glucose, 2-deoxy- Deoxyhalo analogs Benzaldehyde Germ cell tumor In vitro/in vivo antitumor activi 833K-E testicular tumor cells Metabolism, transformed fibrob- ty, 3274 lasts, 2574 Morphological/ultrastructural/ a-Glycerol phosphate dehydrogenase antigenic characteristics, 2500 Glucose-6-phosphatase Mammary neoplasms 833K-LC lymphoblastoid cells Morpholine, N-nitroso- Estrogens, 3158 Morphological/ultrastructural/ Subpopulations, hepatocytes, rat antigenic characteristics, 2500 459 Glycolipids Antigens, neoplasm Glioblastoma multiforme Glucose-6-phosphate dehydrogenase Immunotherapy, 897 Dibutyryl cyclic AMP Mammary neoplasms Mass spectrometry, human, 897 Gonadotropins, chorionic, 4325 Estrogens, 3158 Stomach neoplasms Polyamines /3-Glucuronidase Adenocarcinoma(s), 897 Cerebrospinal fluid, human, 3293 Sarcoma(s) GlycoproteinLV-acetylneuraminic acid Glioma(s) Caloric restriction, mouse, 1680 transferase Urea, 1-(2-chloroethyl)-3-cyclohexyl- Glutamate Mammary neoplasms 1-nitroso- Aspartate Enzyme activity vs tumor burden, Biodistribution, rat, 3473 Normal/neoplastic tissue, rat rat, 3103 Glucocorticoids 4053 Glycoproteins Cell cycle Glutaminase Breast neoplasms Leukocytes, human, 2601 Escherichia coli Carcinoma(s), 316, 662 RPMI 3460 Syrian hamster cells Asparaginase, 1125 Radioimmunoassay, 662 Tumor marker, 662 Receptors, hormone, 2174 Acinetobacter glutaminase- Receptors, hormone Carcinoma(s) asparaginase Isolation and characterization Breast neoplasms, 2557 Antineoplastic agents Clonal proliferation, 563 316 HL-60 cells, 563 Phase I clinical trial, 4546 Ultrastructural study, plasmalem- KG-1 cells, 563 y-Glutamyltranspeptidase ma, 316 Leukemia, myeloblastic, 563 Choline Cell adhesion B-Lymphocytes, 2240 Hepatocarcinogenesis, rat, 3846 Ml myeloid leukemia cells, 3387 Cell differentiation Lymphocytosis, bovine, 2240 Hepatocarcinogenesis Ml myeloid leukemia cells, 3387 Virus, bovine leukemia, 2240 Normal/regenerating/neoplastic liver, rat, 4373 Chymotrypsin Thymoma(s) Inhibition, transformed lym Corticosensitivity, in vitro, 2020 Glutathione phocytes, 4187 DNA synthesis, 2020 Adriamycin Hybrid cells Receptors, hormonal, 2020 Cardiac toxicity, rabbit, 1022 Antibodies, 3850

4898 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Glycoproteins (cont'd) Granulocytes (cont'd) Guanosine cyclic 3':5'-monophosphate Adenosine cyclic 3':5'- Mammary neoplasms Colony stimulating activity, 4031 Adenocarcinoma(s), 1873 Plasma, chick, 4031 monophosphate Enzyme activity vs tumor burden, 12-O-Tetradecanoylphorbol-13- Urine/plasma, cancer patients/ rat, 3103 acetate normals, 3915 Melanoma(s) HL-60 cells, 1469 Adenylyl cyclase Wheat-germ agglutinin resistant vs Griseofulvin Blastogenesis, lymphocytes, hu non-resistant cell lines, 2580 Oxidases, mixed-function man, 379 MÃ©tastases Hyperplastic liver nodules, mouse Carbamylcholine Wheat-germ agglutinin resistant v s Granulocyte-macrophage colony- non-resistant cell lines, 2580 2568 Guanase forming units, 1223 Monosaccharides Nucleic acid synthesis Isoproterenol Cellular adhesion, 1944 Granulocyte-macrophage colony- Lung neoplasms, 2295 Neoplastic cells forming units, 1223 Guanidine Extracellular matrix digestion Phosphodiesterase 3222 Autophagocytosis Blastogenesis, lymphocytes, hu Plasma membrane Ultrastructural study, 1054 man, 379 Radioactive labeling, 1550 Leukemia L1210 cells Prostaglandin E, Sialic acid Ultrastructural study, 1054 Granulocyte-macrophage colony- BHK cells, 1550 Mitochondria forming units, 1223 Radioactive labeling, 1550 Ultrastructural study, 1054 Prostaglandin FÂ¡a Trypsin Guanidine, JV-methyl-./V-nitro-JV- Granulocyte-macrophage colony- Inhibition, transformed lym nitroso- forming units, 1223 phocytes, 4187 Protein kinases Uracil, 5-fluoro- Syrian hamster embryo cells Lymphocytes, normal/neoplastic L1210 cells, 322 Cell transformation, neoplastic 2411 2714 Metabolite pools, 322 12-O-Tetradecanoylphorbol-13- Thymidine incorporation, 2411 Glycosidases DNA methylase acetate Neoplasm mÃ©tastases Acetamide, iodo-, 61 Epidermal cells, mouse, 2653 Tumor enzyme activity, mouse Dithiothreitol, 61 Guanosine, deoxy- 3281 DNA repair DNA Glycosyltransferases Ataxia telangiectasia, 984 Adduct formation, Â«ivitro, 2493 Leukemia, myelocytic DNA synthesis Phosphoramide mustard Blood groups A and H, 268 Intestinal mucosa cells, human Adduct formation, 4138 Prognostic marker, 268 3155 Guanosine, OÂ°-ethyldeoxy- Nicotinamide adenine dinucleotide Gonadotropins, chorionic Carcinogen-modified DNA Adenosine cyclic 3':5'- 3T3 cells, 1797 Immunological assays, rat, 887 Rate of degradation, 1797 monophosphate TPA30-1 transformed placenta! Guanidine, 1,1 -(methylethanediylidene- Guanosine, V-muthyl- cells, 4025 dinitrilo)di- RNA, transfer Choriocarcinoma, 4025 S-Adenosylmethione decarboxylase Methyltransferases, 417 Butyric acid, sodium salt Intestinal mucosa, rat, 2330 Guanosine, deoxy-, 5'-triphosphate Trophoblastic/nontrophoblastic Fibroblasts, 3T3 Thymidine cells, 4519 Polyamine growth regulation, 293 CCRF-CM cells, 1718 Dibutyryl cyclic AMP Spermidine, 293 CBT brain tumor cells, 4325 Spermine, 293 Gullet cancer Chickens TPA30-1 transformed placental L1210 leukemia cells, 4533 cells, 4025 Mitochondria! damage, mouse, in Epidemiology, China, 2633 Trophoblastic/nontrophoblastic vivo, 4533 Haloperidol cells, 4519 Polyamines, 4533 see Butyrophenone. 4-[4-(p-chloro- Choriocarcinoma, 4025 Ornithine decarboxylase phenyl)-4-hydroxypiperidino]4 ' - Glioblastoma multiforme, 4325 Intestina! mucosa, rat, 2330 fluoro- Neoplasms, human Polyamines Heart Heterologous tumors, nude mouse Intestinal mucosa, rat, 2330 Adriamycin 4007 Guanine, O'-methyl- Cardiac toxicity, 4133 Granulocyte-macrophage colony stimu Dimethylamine, JV-nitroso- Helper cells lating factor DNA Adriamycin Hepatoma AH-130 Enzymic removal, liver/lung/ Cytotoxic immune response, in Ascitic fluid, 472 kidney, rat vitro, 2748 Mm-1 cells Guanosine Lymphoma(s) Growth enhancement, 472 B16 melanoma cells Serum/tumor tissue, human 4648 Granulocytes Cytostasis, neoplastic vs normal HL-60 cells cells, mouse, 2147 Hematopoiesis Methyl sulfoxide, 1469 Phosphoramide mustard Bacillus Calmette-Guerin Leukemia, myoblastic Adduct formation, 4138 Bone marrow/spleen, mouse, 80

DECEMBER 1980 4899 Subject Index to Volume 40

Hematopoietic stem cells Hepatoma, Novikoff (cont'd) Hepatoma(s) (cont'd) Carbamylcholine Carminomycm Purine nucleotides, 1286 Proliferation, human cells, 1223 Antitumor activity, 387 Pyrimidine nucleotides, 1286 Chromosome, Philadelphia Carminomycin-11-methyl ether Dibenzo-p-dioxin, 2,3,7,8- Near haploid karyotype, 1354 Antitumor activity, 387 tetrachloro- Isoproterenol Mitochondria Hepatocarcinogenesis, rat, 3616 Proliferation, human cells, 1223 Enzyme activity, 1486 DNA synthesis Prostaglandin E, Normal/neoplastic liver, rat Enzymatic activity, 1235 Proliferation, human cells, 1223 1486 Epinephrine Prostaglandin F2ct Polyribosomes Chemotherapy, 481 Proliferation, human cells, 1223 Antigens, neoplasm, 1367 Hemodynamics, rat, 481 Hematoporphyrin Nucleolar proteins, 1367 Epoxide hydrolase NHIK 3025 carcinoma cells Protein 45/7.8 Normal/hyperplastic/neoplastic DNA single strand, 2915 Isolation and characterization, rat liver microsomes, rat, 2768 Sister chromatid exchanges, 2915 1623 Glutamate Normal/neoplastic tissue, rat Hemoglobin Hepatoma(s) Adriamycin 4053 Liver neoplasms y-Glutamyltranspeptidase Pharmacokinetics, human, 1263 Benzenamine, MN-dimethyl- Hepatocarcinogenesis, rat, 3846 4-((3-methylphenyl)azo)-, 1769 Plasma drug levels, 1263 Normal/regenerating/neoplastic Embryonic proteins, extramedul- Adriamycinol Plasma drug levels, 1263 liver, rat, 4373 lary hematopoietic cells, rat Hyperthermia 1769 Aflatoxin B, Hepatectomized rat, 4739 Peritoneum, mouse, 4081 Heparin Antigens, neoplasm Immunodiagnosis Fibroblasts Complement-dependent cytotox- Tube leukocyte adherence inhibi Medium change response, chicken icity, tumor-bearer sera, rat tion assay, 2928 1753 1691 Inosine phosphorylase Aspartate Normal/differentiating/ Hepatocarcinoma regenerating liver, rat, 3339 see Hepatoma(s) Normal/neoplastic tissue, rat 4053 Interferon Hepatocytes Autoantigens Inhibitor, ascites fluid, 2534 Benzo(a)pyrene, (+ )-trans-7,8- Complement-dependent cytotox- Isolation and characterization dihydro-7,8-dihydroxy- icity, tumor-bearer sera, rat 2534 Cell transformation, neoplastic 1691 Ischemia 1281 Bacillus Calmette-Guerin Normal/regenerating/neoplastic/ Chromosomal damage, rat, 1281 Antigens, neoplasm, 4197 neonatal liver, rat, 1286 Growth inhibition, rat, 1281 Intralesional immunization, gui Listeria monocytogenes Cell culture nea pig, 4197 Tumor growth, guinea pig, 3211 Collagen geli/nylon mesh, 4552 Tumor growth, guinea pig, 3211 MÃ©tastases Microfilaments 3214 Chymostatin, 2539 Actin, 4552 Barbituric acid, 5-ethyl-5-phenyl- Elastina!, 2539 Nitrosamines Acetamide, N-fluoren-2-yl-, 3268 Leupeptin, 2539 Mutagenic metabolites, 406 Benzenamine, N,N-dimethyl-4-((3- Mevalonic acid methylphenyl)azo)- Coenzyme A reducÃase,3- Hepatoma, Morris hydroxy-3-methylglutaryl D-Galactose Enzyme activity, 1658 Metabolism, rat, 2026 Phospholipids, plasma membrane, 4717 Poly A rat, 909 Normal/neoplastic liver, rat RNA, 1449 Cell differentiation 4717 Protein 45/7.8 Enzyme activity, 725 Nitrosomethylethylamine derivatives Isolation and characterization, rat Phenotype diversity, 725 Carcinogenicity, rat, 19 1623 Cell membrane potential Norepinephrine Superoxide dismutase Normal/neoplastic cells, rat/ Chemotherapy, 481 Mitochondria, normal/neoplastic mouse, 1830 Hemodynamics, rat, 481 liver, rat, 3686 Cholesterol Ornithine decarboxylase Superoxide radical Mevalonic acid, 4717 Normal/regenerating/neoplastic Mitochondria, normal/neoplastic Choline liver, rat, 4373 Barbituric acid, 5-ethyl-5-phenyl- liver, rat, 3686 Propionibacterium acnes Undine diphosphogalactose 4'- 3846 Tumor growth, guinea pig, 3211 Coenzyme A reducÃase,3-hydroxy-3- epimerase Protease inhibitors Metabolism, rat, 2026 methylglutaryl Elastina!, 2539 Uridine diphosphoglucose:galactose- Mevalonic acid, 4717 Protein 45/7.8 1-phosphate uridyltransterase CTP synthetase Isolation and characterization, rat Metabolism, rat, 2026 Normal/neoplastic/regenerating 1623 tissue, rat/human, 3921 Protein kinase Hepatoma, Novikoff Cyclophosphamide Normal/regenerating/neoplastic Adriamycin Neoplasm growth, 2179 liver, rat, 4373 Antitumor activity, 387 Deoxyribonucleoside triphosphates Pyrimidine synthesis

4900 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Hepatoma(s) (cont'd) Hormones, /3-adrenergic (cont'd) Hydrocortisone (cont'd) Enzymatic activity, 1235 Vincristine Tumor-bearing vs normal neona Streptococcus mutans Cell proliferation, 2695 tal/adult rat, 3697 Tumor growth, guinea pig, 3211 Vindesine Thyronine, 3,3',5-triiodo- Cell proliferation, 2695 Hydroxamic acids Hepatocyte proliferation, rat Salmonella typhimurium 2417 Horseradish peroxidase Alkaline phosphatase DNA carbamoylation vs Hereditary diseases Placenta, 4064 mutagenicity, 4704 Radiosensitivity, human cells Hyaluronidase JV-Hydroxy-2-acetylaminofluorene 926 see Acetamide, N-hydroxy-AT- X-rays Mammary neoplasms Cell transformation, neoplastic fluoren-2-yl- Fibroblasts, 920 2383 Radiosensitivity, 920 JV-Hydroxy-2-aminofluorene Xeroderma pigmentosum Hybrid cells see Hydroxylamine, AT-fluoren-2-yl- Epidemiological study, Egypt, 13 Antibodies Cytotoxicity, lymphocytes virus- JV-Hydroxy-AyV-diacetylbenzidine Heterocyclic nitrosamines see Benzidine, N-hydroxy-N.W- Piperazine, 1,4-dinitroso- producing, 3850 diacetyl- Transplacental/tranlactational Hybridoma(s) Ai-Hydroxyarylamides carcinogenesis, mouse, 2925 Antibodies, neoplasm N,O-Acyltransferase Binding, cultured/freshly isolated Hexamethylmelamine Substrate specificity, 834 neoplastic cells, 3602 Hydroxylamine, Af-fluoren-2-yl- Pentamethylmelamine Me-43 melanoma cells Pharmacokinetics, mouse, 2762 P3-NSI/lAg4 melanoma cells DNA adducts, 834 Plasmacytoma, 2762 2523 4-Hydroxycyclophosphamide- Histaminase aldophosphamide Hydatidiform mole see Diamine oxidase LÃ¡clatedehydrogenase-Z Cyclophosphamine Cytotoxic metabolites, blood, Isoenzyme, trophoblast cell, 283 Misiones mouse, 174 see a/so Proteins, nuclear Hydrazine, 1,2-dimethyl- Aflatoxin B, Hydroxylamine, TV-fluoren-2-yl- Cell transformation, neoplastic Liver, rat, in vivo, 4343 N-Hydroxyarylamides Colonie neoplasms, 1774 Butyric acid, 4-[p-bis(2- DNA adducts, 834 chloroethyl)aminophenyl]- Citrobacter freundii Carcinogenesis, colon, mouse, 4451 Hydroxylamines, yV-acyl-N-l-fluorenyl- HeLa cells, 967 Colonie neoplasms Arylhydroxamic acid acyltransferase Posttranscriptional/ Immune response, mouse, 2475 posttranslational inhibition Ames test, 1204 Tumor incidence/histopathology, Enzyme activity, liver, rat, 1204 967 rat, 2661 Deacylase HL-A antigens Dietary lipotropes Ames test, 1204 Immune serums Carcinogenesis, liver, rat, 2802 Enzyme activity, liver, guinea pig Indirect rosette microassay, 2252 DNA synthesis 1204 Hodgkin's disease Carcinogenesis, colonie mucosa, Sulfotransferase rat, 4589 Ames test, 1204 Mortality rate Protein kinase Enzyme activity, liver, rat, 1204 Epidemiological study, New Jer sey-New York-Philadelphia Carcinogenesis, colonie mucosa, rat, 4589 Hydroxyurea 439 see Urea, hydroxy- Proteins, nuclear Homocysteine Carcinogen susceptibility, mouse Hyperdiploidy Methioninase 1774 PC-3 cells CCRF-HSB-2 cells, 634 Colonie neoplasms, 1774 Cytogenetics, 524 F-136-35-56 cells, 634 a-Tocopherol Normal vs malignant cells, 634 Carcinogenicity, mouse, 1329 Hyperglycemia Hyperthermia Colonie neoplasms, 1329 Hormone therapy Sarcoma(s), 4728 Breast neoplasms Hydrocortisone Tumor blood supply, rat, 4728 Mathematical model, 2423 Aminotransferases Hyperplasia MÃ©tastases,2423 AH 130 tumors, rat, 877 Ovarian/adrenal gland function Thymus involution, rat, 877 Bladder neoplasms Urothelial regeneration response, 4043 Chlorozotocin rat, 3709 Receptors, hormone, 2423 Chromatin, binding, 3697 Thymidine kinase Hyperthermia Hormones Tumor-bearing vs normal, neona Urea, 1-ethyl-1-nitroso- Chinese hamster ovary cells tal/adult rat, 744 pH vs cytotoxicity, 4019 Hepatocarcinogenesis, mouse Thymidylate synthetase C3H 10T1/2 cells 1538 Tumor-bearing vs normal neona Malignancy vs heat/antibiotic Hormones, /3-adrenergic tal/adult rat, 744 sensitivity, 3763 Vinblastine Urea, 1-(2-chloroethyl)-3-cyclohexyl- HA-1 Chinese hamster ovary fibrob- Cell proliferation, 2695 1-nitroso- last cells

DECEMBER 1980 4901 Subject Index to Volume 40

Hyperthermia (cont'd) Hypolipidemic peroxisome proliferators Imidazole-4-carboxamide-l-ÃŸ-D-ribo- Effect of cell medium, 4501 (cont'd) furanosyl, 5-amino-, 5 -monophos- HeLa cells Ames test, 36 phate Pyrazofurin 5'-monophosphate Cytotoxicity, 3459 Hypophysectomy Glucose, 3459 Furine biosynthesis, rat, 1482 Receptors, hormone Hypoxia, 3459 Mammary neoplasms, 1612 Cystadenoma, mucinous Imidazolecarboxamide Derivatives Case report, 256 Hypothyroidism Methotrexate, 256 Benz(a)anthracene, 7,12-dimethyl- Antitumor activity, mouse, 3810 Thermal infusion filtration system Mammary neoplasms, 2336 Immune complexes 256 Hypoxan thine Lupus erythematosus Thiotepa, 256 Serum levels, dog, 3627 Fibrosarcoma(s) Methotrexate Immunosuppression, 650 Mammary neoplasms Multifractionated treatment, Serum levels, dog, 3627 mouse, 2045 Hypoxanthine-guanine phosphoribosyl- Hepatoma(s) transferase Immune RNA Peritoneum, mouse, 4081 Phorbol-12,13-didecanoate Kidney neoplasms Lymphocyte-mediated tumor Hyperglycemia Intercellular communication, epi Sarcoma(s), 4728 dermal cells/fibroblasts, mouse cytolysis, 2377 Tumor blood supply, rat, 4728 2935 Phase I clinical trial, 2377 Mitomycin C 12-O-Tetradecanoylphorbol-13- Melanoma(s) Lymphocyte-mediated tumor Heat sensitivity, 1165 acetate LoVo cells, 1165 Intercellular communication, epi cytolysis, 2377 Plat in um( II). c/s-diamminedichloro- dermal cells/fibroblasts, mouse Phase I clinical trial, 2377 Cytotoxicity enhancement, 1136 2935 DNA cross-linking, 1136 Immune serums Antigens, neoplasm Heat sensitivity, 1165 Hypoxia Lo Vo cells, 1165 Indirect rosette microassay, 2252 Mitomycin C HL-A antigens Polyamines EMT6 mouse mammary tumor Chinese hamster ovary cells, 432 Indirect rosette microassay, 2252 cells, 2356 Lymphoma(s) Cytotoxicity, 432 Sarcoma 180 cells, 2356 Ornithine decarboxylase, 432 Antigens, neoplasm, 3147 y32-Microglobulin Sarcoma(s) IARC monograph Tumor growth, rat, 2829 Indirect rosette microassay, 2252 Carcinogens SCK tumor cells Human, 1 Immunity, cellular Heat sensitivity, in vivo/in vitro L cells 1130 Tumorigenicity vs immunological Vascular occlusion, 1130 IgA properties, 3252 Thermal infusion filtration system Antibody, antiidiotypic Colonie neoplasms Peritoneal perfusion, 253 MOPC 315 myeloma cells, 1630 Tumor-growth inhibition, mouse, 717 Preclinical evaluation, dog, 253 Immune response, mouse, 1630 Cyclophosphamide Thermotolerance Immune response, mouse, 2135 Critical temperature, 4485 IgG Plasmacytoma, 2135 Mathematical analysis, cell killing Carcinoembryonic antigen Hydrazine, 1,2-dimethyl- 4485 Urea, 1-(2-chloroethyl)-3-cyclohexyl- Antigen-antibody complexes, 497 Colonic neoplasms, 2475 1-nitroso- Ovarian neoplasms, 502 Keratoacanthomas Ependymoblastoma, 2726 Radioimmunodetection, human Neoplasm transplantation, 1668 Synergestic action, mouse, .2726 patients, 497, 502 Mammary neoplasms Receptors, Fc Tumor growth, mouse, in vivo Hyperthermia, localized Lymphoma(s), 4648 3977 Methotrexate Suppressor cells Ovarian neoplasms Liposomes, 1388 Mammary neoplasms, 3477 Lymphocyte-inhibitory factor Neoplasm transplantation 1842 Antitumor activity, mouse, 26 Plasmacytoma Fibrosarcoma(s), 26 IgM Uracil, 5-fluoro-, 2790 Statistical analysis, mouse cells Cyclophosphamide Sarcoma(s) MOPC 104E myeloma cells Letter to the editor, 959 Macrophage activation, mouse, in 2372 Tissue pH vitro, 2054 Platinum(II),diamminedichloro-, cis Letter to the editor, 959 Suppressor cells Tumor size MOPC 104E myeloma cells Blood levels, cancer patients Letter to the editor, 959 2372 3134 Receptors, Fc Hypervitaminosis A Uracil, 5-fluoro- Lymphoma(s), 4648 Retinoids Urea, l,3-bis(2-chloroethyl)-l- Immune response, mouse, 2790 Binding affinity assay, 212 nitroso- Immunity, humoral Hypolipidemic peroxisome proliferators MOPC 104E myeloma cells Virus, feline leukemia DNA synthesis 2372 Natural infection, 823

4902 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Immunization Immunotherapy (cont'd) Interferon (cont'd) Bacillus Calmette-Guerin Cyclophosphamide, 4428 Leukemia, myelocytic Neoplasm transplantation, 1036 Maleic anhydride-divinyl ether copo- Cell differentiation, 2919 Neoplasm transplantation lymer polyanions Poly I-Poly C Fibrosarcoma(s), 1036 Mouse, in vivo, 1967 Antitumor activity, mouse, 614 RNA Melanoma(s), 614 Immunodeficiency Cell-mediated cytotoxicity, Suppressor cells splenocytes, mouse, 1762 Intracytoplasmic A particles Blood levels, cancer patients see Inclusion bodies, viral 3134 Inclusion bodies, viral Virus, type C lodoacetate Immunodiagnosis Sacchammyces cerevisiae Letter to the editor, 1765 Hepatoma(s) Mitotic recombination/ Tube leukocyte adherence inhibi Indomethacin mutagenicity, 2323 tion assay, 2928 Ornithine decarboxylase Ultraviolet rays Immunosuppression Skin neoplasms, 308 Mitotic recombination/ Colonie neoplasms Plasminogen activators mutagenicity, 2323 Prostaglandin biosynthesis, 849 Blastogenesis inhibition factor, 29 Iron Cyclophosphamide Prostaglandins Synthesis inhibitors, 308 NRK cells Fibrosarcoma(s), 2756 Cell transformation, viral, 786 Prostaglandins E Cytosine, 1-/J-D-arabinofuranosyl- Polypeptides, plasma membrane Immune response, mouse, 3491 Granulopoietic precursors, growth 786 in vitro, 2507 Leukemia, radiation 12-O-Tetradecanoylphorbol-13- RFM mouse, 3403 Isobutylmethylxanthine acetate see Xanthine, l-methyI-3-isobutyl- Mammary neoplasms Lymphocytes, bovine, 776 Immune response, rat, 3484 Oxygen-dependent synthesis, 776 Isophosphoramide mustard Methotrexate see Phosphorodiamidic acid, N,N'- C57BL/6J spleen cells, 650 Inflammation di-(2-chloroethyl)- Folinic acid, 650 Resiniferatoxin Isoproterenol Hypoxanthine, 650 12-O-Tetradecanoylphorbol-13- Adenosine cyclic 3':5'- Thymidine, 650 acetate, 1400 Uridine, 5-iodo-5'-amino-2',5'- monophosphate Granulocyte-macrophage colony- dideoxy- Inosine phosphorylase forming units, 1223 Imrnune response, mouse, 3491 Hepatoma(s) Uridine, 5-iodo-2'-deoxy- Butyric acid Normal/differentiating/ Adenosine cyclic 3':5'- Immune response, mouse, 3491 regenerating liver, rat, 3339 Kidney neoplasms, 3339 monophosphate, 240 Colonie neoplasms Insulin Adenosine cyclic 3':5'- Immunotherapy Benz(a)anthracene, 7,12-dimethyl- monophosphate, 2529 Azimexon Mammary neoplasms, 2343 Guanosine cyclic 3':5'- Mouse, in vivo, 1967 Breast neoplasms Bacillus Calmette-Guerin monophosphate Epidermal growth factor, 2361 Granulocyte-macrophage colony- Lung neoplasms, 3455 4-Methylphorbol-12,13-didecanoate forming units, 1223 Mouse, in vivo, 1967 Glucose, 3827 Tumor growth, guinea pig, 3214 Leukemia, myelocytic Pancreatic islets, rat, 3827 Proliferation, human cells, 1223 Bestatin 12-O-Tetradecanoylphorbol-13- Mouse, in vivo, 1967 Kaempferol Cell-mediated cytotoxicity, spleno- acetate Glucose, 3827 Bracken fern cytes, mouse Pancreatic islets, rat, 3827 Carcinogenicity, rat, 3468 RNA, 1763 L2C leukemia cells Interferon Keratoacanthomas Tumor growth, guinea pig, 3211 Carcinoma, Ehrlich tumor Neoplasm transplantation Line 10 hepatocarcinoma cells Inhibitor, ascites fluid, 2534 Hair follicle cycle, nude mouse Tumor growth, guinea pig, 3211 Isolation and characterization 1668 Corynebacterium parvum 2534 Immunity, cellular, 1668 Antitumor activity, mouse, 4617 L cells Kidney neoplasms Killer cells, 4159 Cell differentiation, 2919 Cell transformation, neoplastic Retinyl palmitate, 4617 Virus, Newcastle disease, 2919 Polypeptides, 3728 Glycolipids Ml mouse leukemia cells HKC-400 renal carcinoma cells Antigens, neoplasm, 897 Cell differentiation, 2919 Cell cycle, in vitro vs in vivo, Hepatoma(s) Polyinosinic-polycytidylic acids hamster, 4796 Antigens, neoplasm, 4197 2919 CTP synthetase Bacillus Calmette-Guerin, 4197 Hepatoma(s) Normal/neoplastic/regenerating Immunity, cellular Inhibitor, ascites fluid, 2534 tissue, rat/human, 3921 Letter to the editor, 492 Isolation and characterization Immune RNA Leukemia(s) 2534 Lymphocyte-mediated tumor Combination therapy, mouse Induction impairment, mouse cytolysis, 2377 4428 Tumor-mediated factors, 873 Inosine phosphorylase, 3339

DECEMBER 1980 4903 Subject Index to Volume 40

Killer cells Leukemia I 121(1 Leukemia, lymphoblastic Corynebacterium parvum see also L1210 cells Adenine, 9-/3-D-arabinofuranosyl- Cell-mediated cytotoxicity, mouse Acetone, chlorohydroxy- DNA synthesis, 1405 4159 Deoxyhalo analogs, 3274 Adenine, 9-/3-D-arabinofuranosyl-2- Lymphoma(s), 4159 Adriamycin fluoro- Antitumor activity, 387 DNA synthesis, 1405 Circadian bioperiodic response, Deoxynucleosides Lactalbumin 5'-Ribonucleotide phosphohydro- Breast neoplasms mouse, 1511 Prolactin, 486 Azimexon lase, 3383 Mouse, in vivo, 1967 Protein kinases Bacillus Calmette-Guerin Lymphocytes, normal/neoplastic Lactate dehydrogenase-Z Mouse, in vivo, 1967 2714 BEWO cells Bestatin Receptors, glucocorticoid Isoenzyme, trophoblast cell, 283 Mouse, in vivo, 1967 Cell cycle, 2601 Choriocarcinoma Carminomycin Thymidine Cytidine, 5'-triphosphate, deoxy- BeWo cells, 3408 Antitumor activity, 387 OMEGA-Z cells, 3408 Carminomycin-11-methyl ether 1718 Isoenzyme, trophoblast cell, 283 Antitumor activity, 387 Growth inhibition, 1718 Hydatidiform mole Cyclophosphamide Leukemia, lymphocytic Isoenzyme, trophoblast cell, 283 Circadian bioperiodic response, Cytosine, 1-/3-D-arabinofuranosyl- JEG-3 cells mouse, 1511 Drug uptake/metabolism, bone Isoenzyme, trophoblast cell, 283 Sulfhydryl derivatives, 3704 marrow/peripheral blood cells Tumorigenicity/toxicity, mouse 2441 Lactulose 3704 Undine, tetrahydro-, 2441 Cytidine dialdehyde BifÃdobacteriumbifÃdum Protein kinases Bacteria distribution, mouse, in Antitumor activity, mouse, 598 Lymphocytes, normal/neoplastic DNA synthesis, 598 vivo, 2061 Cytosine, l-/3-D-arabinofuranosyl- 2714 Large cell carcinoma Liposome encapsulation, 630 Leukemia, MCDV-12 ascitic see Carcinoma(s) DL-Glycerol DNA polymerases Deoxyhalo analogs, 3274 Inhibition factor, mouse, 758 Lectins Levamisole Leukemia, myeloblastic Aneuploidy Antitumor activity, in vivo, 4813 Growth kinetics, human marrow Purine-6-thiol, 4813 Antigens, neoplasm Lymphocyte typing test, 3218 cells, 1292 Maleic anhydride-divinyl ether copo- T-Lymphocytes, 3218 Macrophages lymer polyanions HL-60 cells Tumor cell lysis, 3798 Mouse, in vivo, 1967 Colony formation, 1858 Sister chromatid exchange Thrombocytopenia KG-1 cells Growth kinetics, human marrow Megokaryocytopoiesis, mouse Colony formation, 1858 cells, 1292 667 Chediak-Higashi disorder Vaccines Leukemia, acute undifferentiated Carrageenan, 3832 Cell inclusions, 4473 Deoxynucleotidyl transferase Cytosine, 1-/3-D-arabinofuranosyl- Immune response, mouse, 3839 Cytosine, 1-/3-D-arabinofuranosyl- Lymphoblasts, 4048 Mitomycin C, 3839 5'-triphosphate, 588 Diagnostic markers Potentiation immune response, Lymphoblasts, 4048 mouse, in vivo, 3832 Drug uptake/metabolism, bone marrow/peripheral blood cells Suppressor cells, 3832 Leukemia, AKR 2441 Daunorubicin Vinblastine Uridine, tetrahydro-, 2441 Cell proliferation, 2695 Dose scheduling, mouse, 2835 Glucocorticoids Vincristine Leukemia, chronic myelocytic Cell proliferation, 2695 Receptors, hormone, 563 Antigen, nonspecific cross-reacting Vindesine Glycoproteins Diagnosis, 2039 Cell proliferation, 2695 Cell adhesion, 3387 Serum/bone marrow cells, nor- Cell differentiation, 3387 mal/neoplastic, 2039 Isolation and characterization, 4187 Carcinoembryonic antigen Granulocytes Serum/bone marrow cells, nor- Colony stimulating activity, 4031 mal/neoplastic, 2039 Plasma, chick, 4031 Leukemia LSTRA Macrophages Azimexon Leukemia, granulocytic Colony stimulating activity, 4031 Mouse, in vivo, 1967 Fucosyltransferase Bacillus Calmette-Guerin Plasma, chick, 4031 Enzyme activity, plasma, human 12-O-Tetradecanoylphorbol-13- 3576 Mouse, IT?vivo, 1967 Bestatin acetate Leukemia, hairy cell Mouse, in vivo, 1967 Cell maturity, 1469 Proteins, cellular Maleic anhydride-divinyl ether copo- Leukemia, myelocytic Disease subtype protein pattern lymer polyanions Carbamylcholine 1907 Mouse, in vivo, 1967 Proliferation, human cells, 1223

4904 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Leukemia, myelocytic (cont'd) Leukemia(s) (cont'd) Leupeptin Chromosome, Philadelphia Electrophoretic mobility, 4751 Fibroblasts Near haploid karyotype, 1354 Glucose, 4751 Medium change response, chicken Cytosine, 1-/8-D-arabinofuranosyl- Oxygen, 4751 1753 Drug uptake/metabolism, bone Lymphoid cells MÃ©tastases marrow/peripheral blood cells Splenectomy and/or irradiated Hepatoma(s), 2539 2441 nude mouse, 2588 Lung neoplasms, 2539 Undine, tetrahydro-, 2441 Transplantation, heterologous 2588 Levamisole Deoxynucleotidyl transferase Leukemia L1210 Lymphoblasts, 4048 Cyclophosphamide Dose schedule, mouse, 2135 Antitumor activity, in vivo, 4813 Diagnostic markers Purine-6-thiol, 4813 Lymphoblasts, 4048 Cytosine, 1-/3-D-arabinofuranosyl- L-Ethionine Drug uptake/metabolism, bone Levodopa Cell differentiation, 3206 marrow/peripheral blood cells see Alanine, 3-(3,4- Glycosyltransferases 2441 dihydroxyphenyl)-, L- Blood groups A and H, 268 Undine, tetrahydro-, 2441 DNA polymerases Leydig cells Prognostic marker, 268 17/3-Estradiol Interferon Deoxynucleotidyltransferase Carcinogenic effect, mouse, 1006 Cell differentiation, 2919 1014 Isoproterenol Immunotherapy Linoleic acid Proliferation, human cells, 1223 Combination therapy, mouse Carcinoma, Ehrlich tumor Prostaglandin E, 4428 Metabolism, 2447 Proliferation, human cells, 1223 Cyclophosphamide, 4428 Morris hepatoma 7777 cells Prostaglandin F2a Leukemia-associated inhibitory ac Complement-mediated cytolysis tivity Proliferation, human cells, 1223 1084 Prostaglandins E Infected, neonatal/adult mouse Cell differentiation, 2512 3928 Lipids Granulopoietic precursors, 2507 Virus, Abelson, 3928 Cell membrane 2512 Lymphoma(s) Platelet aggregation, 1217 Animal model, mouse CNS inva Neoplasm metastasis Receptors, glucocorticoid sion, 3130 Platelet aggregation, 1217 Cell cycle, 2601 Mitochondria 12-O-Tetradecanoylphorbol-13- Calcium transport, 221 acetate Oxidative functions, 221 HL-60 leukemia cells, 3674 Leukemia, myelogenous acute Monosialoganglioside see Leukemia, myeloblastic Binding, normal/neoplastic Liposomes Adriamycin thymocytes, mouse, 2808 Mortality rate Carcinoma, Lewis lung, 1532 Leukemia, nonlymphocytic Cardiotoxicity, mouse, 1532 L-Ascorbic acid Epidemiological study, New Jer sey-New York-Philadelphia P388 leukemia cells, 1532 Bone marrow cells, human, in 439 Drug entrapment, 1532 vitro, 1062 Positive/negative charge, 1532 Oncogenic viruses Flavone, 3,3',4',5,7-pentahydroxy- Leukemia P388 Review, 3405 see also P388 cells Proteins, cellular Growth inhibition, 1344 Cytosine, 1-/8-arabinofuranosyl- Disease subtype protein pattern Macrophages Macrophage-activating agents Metastases, 4758 1907 Surface-active agents Receptors, glucocorticoid 4460 Growth inhibition, in vivo vs in Leukocytes, human, 2601 Uptake, lung, mouse, 4460 vitro, 1173 Theophylline Methotrexate Uracil, 5-fluoro- Mortality, mouse, 2202 Hyperthermia, local, 1388 Lipophilic derivative, 4758 Urea, l,3-bis(2-cnloroethyl)-l- Preferential release, LI210 tumor, MÃ©tastases, 4758 nitroso-, 2202 mouse, 1388 Virus, Gross murine leukemia Listens monocytogenes Animal model, mouse CNS inva Leukemia, promyelocytic Line 10 hepatocarcinoma cells 12-O-Tetradecanoylphorbol-13- sion, 3130 Tumor growth, guinea pig, 3211 acetate Leukocyte adherence inhibition test Hepatoma(s) Cell differentiation, 3674 Macrophages Tumor growth, guinea pig, 3211 Lipids, 3674 Diagnosis, neoplastia disease Lithocholic acid 4791 Leukemia, radiation L1210 cells RFM mouse, 3403 Leukocyte migration-inhibition assay DNA repair, 2666 Lung neoplasms DNA, single strand, 2666 Leukemia(s) 4'-(9-Acridinylamino)methanesulfon-m Immune response, human, 3598 Liver microsomes -anisidide Solid tumor infiltration, 3598 Barbituric acid, 5-ethyl-5-phenyl- Phase I and II clinical trials Leukocytes Enzyme activity, 1658 3304 Cyclophosphamide Precancerous conditions, liver, rat Ascites tumor cells Mechanism of action, 395 1658

DECEMBER 1980 4905 Subject Index to Volume 40

Liver neoplasms Lung neoplasms (cont'd) B-Lymphocytes Diethylamine, N-nitroso- Mesothelioma Receptors, hormone Acetamide, JV-fluoren-2-yl, 1112 Ship-building workers, 3875 Glucocorticoids, 2240 Hemoglobin Neoplasm mÃ©tastases Sarcoma(s) Benzenamine, JV.JV-dimethyl- Chymostatin, 2539 Macrophage activation, mouse, in 4-((3-methylphenyl)azo)-, 1769 Elastina!, 2539 vitro, 2054 Embryonic proteins, extramedul- Leupeptin, 2539 lary hematopoietic cells, rat Lysosomal enzymes, 3281 Lymphocytes, null-type 1769 Tumor enzyme activity, mouse Deoxynucleosides Urea, JV-methyl-JV-nitroso- 3281 5'-Ribonucleotide phosphohydro- Acetamide, Ã•V-nuoren-2-yl, 1112 Plasminogen activators lase, 3383 Isolation and characterization 841 Lung neoplasms Urokinase, 841 T-Lymphocytes Adenocarcinoma(s) Protease inhibitors Adriamycin Nucleic acid synthesis, 2295 MÃ©tastases, 2539 Cytotoxic immune response, in Anthracenes, halomethyl Quinoline, 4-nitro-, 1-oxide vitro, 2748 Carcinogenicity, mouse, in vivo Caffeine, 1332 Antigens, neoplasm 782 Carbamic acid, ethyl ester, 1332 Fibrosarcoma(s), 2129 Antigens, neoplasm Saccharin Immune response, rat, 2129 Identification and characterization Tumor promotion, mouse, 4322 Leukemia, myeloblastic 2153 Surface-active agents Antigens, neoplasm, 3218 Ary [sulfatases Growth inhibition, in vivo vs in Lymphoma(s) Adenocarcinoma(s), 3804 vitro, 1173 Receptors, Fc, 4648 Carcinoma, epidermoid, 3804 Virus, lÃ¡clate dehydrogenase Serum/tumor tissue, human Bacillus Calmette-Guerin Carbamic acid, ethyl ester, 64 4648 Hamster, Syrian golden, 3455 Immune response, mouse, 64 Ovarian neoplasms Benzo(a)pyrene Ascites fluid, human, 4495 Animal model, hamster, dog Blastogenic response, 4495 Lupus erythematosus 2288 Sarcoma(s) Immune complexes Sustained release, 2288 Macrophage activation, mouse, in Serum levels, dog, 3627 Benzylamine, Af-methyl-AT-nitroso- vitro, 2054 Target tissues, 1921 Calcitonin Luteinizing hormone Lymphoma(s) Adenylate cyclase, 1311 Aryl hydrocarbon hydroxylase Acetone, chlorohydroxy- Carcinoma, oat cell Testis, hypophysectomized rat Deoxyhalo analogs, 3274 Carcinoembryonic antigen, 4420 2486 Antigens, neoplasm Cell culture, 3502, 4356 Immune serums, 3147 Cell self-renewal, 1820 Epoxide hydrase Testis, hypophysectomized rat Serotherapy, case report, 3147 Clonal heterogeneity, human cells 2486 Lymphoid cells 4295 Glutathione transferase Splenectomy and/or irradiated Colony growth, 1820 Testis, hypophysectomized rat nude mouse, 2588 Growth requirements, 3502 2486 Transplantation, heterologous Carcinoma(s) 2588 Nucleic acid synthesis, 2295 Chromosome aberrations B16 melanoma cells Lymphocytes Benz(a)anthracene, 7,12-dimethyl- Cell surface properties, 1645 Adenyl cyclase 2609 MÃ©tastases, 1645 Phosphodiesterase, 379 Cryopreservation Corynebacterium parvum Mitogens Immunological typing, tumor Retinyl palmitate, 4617 Phosphodiesterase, 379 cells, 2890 Cyclophosphamide Mitomycin C Demographic/industrial data Sulfhydryl derivatives, 3704 Cytogenetics, human, 477 Mortality rate, United States Tumorigenicity/toxicity, mouse Sister chromatid exchange, 477 2645 3704 Nicotinamide adenine dinucleotide DNA polymerases Diamine oxidase DNA-damaging agents, direct/ Deoxynucleotidyltransferase In vivo vs in vitro activity, 1990 indirect, 1803 1014 L-Dopa decarboxylase Sarcoma, mast cell Drug therapy In vivo vs in vitro activity, 1990 Zonal rotor centrifugation, 1791 Somatic cell damage, children Epidermoid carcinoma(s) 12-O-Tetradecanoylphorbol-13- 4786 Nucleic acid synthesis, 2295 acetate Flow analysis Leukocyte migration-inhibition assay Binding assay, 1119 Cell cycle, normal vs neoplastic Immune response, human, 3598 Mitogenic response, 1119 703 Solid tumor infiltration, 3598 Urogenital neoplasms Cell size, 703 Macrophages Absolute lymphocyte count, 4612 DNA content, 703 Animal model, beige mouse Density gradient-purified cell sus DL-Glycerol 3934 pensions, 4612 Deoxyhalo analogs, 3274 Antitumor activity, 3934 Prognosis, 4612 Leukemia(s)

4906 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Lymphoma(s) (cont'd) Macrophages (cont'd) Mammary neoplasms (cont'd) Animal model, mouse CNS inva Tumor cell lysis, 3798 Receptors, hormone, 2343 sion, 3130 Leukemia, myoblastic Retinyl acetate, 1140 T-Lymphocytes Colony stimulating activity, 4031 RNA, messenger, 362 Receptors, Fc, 4648 Plasma, chick, 4031 Steroid binding, rat, 1612 Serum/tumor tissue, human Leukocyte adherence inhibition test Broparestrol 4648 Diagnosis, neoplastic disease Prolactin, 1674 Mortality rate 4791 Carcinoma(s) Epidemiological study, New Jer Lewis lung tumor Ovariectomized rat, 3112 sey-New York-Philadelphia Animal model, beige mouse Ultrastructure, 3112 439 3934 Cell culture Oncogenic viruses Antitumor activity, 3934 Preneoplastic cells, mouse, 3982 Review, 3405 Liposomes Cell cycle Pituitary gland Macrophage-activating agents Virgin/parous rat, 2677 Estrogen, 2437 4460 Cell subpopulations Growth in vivo, Nb rat, 2437 Uptake, lung, mouse, 4460 Tumor growth, mouse, in vivo Prolactin Virus, Friend leukemia 3977 Cell proliferation, Nb rat, 2433 Immune response, mouse, 557 Cell transformation, neoplastic Tumorilysin Passive serum therapy, 557 Colchicine, 2383 Characterization, 1255 Wheat germ agglutinin Collagenase, 2383 Virus, Friend C3H/He mammary carcinoma Cytochalasin B, 2383 Immune response, rat, 448 cells, 3798 Hyaluronidase, 2383 Runting syndrome, 448 MH134 hepatoma cells, 3798 Surface-related changes, 2383 Virus, Gross MM48 mammary carcinoma cells Trypsin, 2383 Immune response, rat, 448 3798 C3H/He mammary carcinoma cells Runting syndrome, 448 Tumor cell lysis, 3798 Growth characteristics, lung, X-rays mouse, in vivo, 3495 Bone marrow reconstitution, Maleic anhydride-dmnyl ether co- WAZ-2T cells polymer polyanions mouse, 357 Tumorigenicity, mouse, 1812 Carcinoma M109 Somatic cell damage, children Cyclophosphamide Mouse, in vivo, 1967 4786 Cell kinetic recovery, rat, 737 Leukemia L1210 Spleen cell reconstitution, mouse Dexamethasone 357 Mouse, in vivo, 1967 Butyrophenone. 4-[4-(p-chloro- Leukemia LSTRA phenyl)-4-hydroxypiperidino]4 ' - Lymphosarcoma Mouse, in vivo, 1967 fluoro-, 1863 Neoplasm transplantation 2,6,10,14-Tetramethylpentadecane Malic enzyme Dietary fat Benz(a)anthracene, 7,12-dimethyl- 2229 Mammary neoplasms Estrogens, 3158 2785 Lysosomal enzymes Epithelium Anchorage independent/ Lung neoplasms Malondialdehyde Neoplasm mÃ©tastases,3281 see Propanediol dependent cells, 1812 Myeloid leukemia cells Basal lamina, 1600 Cell differentiation, 914 Mammary neoplasms Epithelial cell junctions, 1588 17/3-Estradiol Retinoids Adenocarcinoma(s) Myeloid leukemia cells, 914 Benz(a)anthracene, 7,12-dimethyl- Receptors, hormone, 1050 Puromycin, 914 368 Estrogens Sarcoma, Crocker 180 Glycoproteins, 1873 Enzyme activity, tumor/uterus, Neoplasm mÃ©tastases, 3281 Histological/ultrastructural study, rat, 3158 mouse, 1588 Glucose-6-phosphate dehydroge- Hormone stimulation, mouse nase, 3158 Macromomycin 368 a-Glycerol phosphate dehydroge- Chemotherapy Immune response, rat, 3484 nase, 3158 Letter to the editor, 1764 Neoplasm metastasis, 1588 Malic enzyme, 3158 Macrophages Solid vs ascites form, rat, 1873 Peroxidase, 3158 EMT-6 mouse adenosarcoma cells Virus, murine mammary tumor Receptors, hormone, 235 Cytotoxicity vs cell cycle, 4622 368 Glycoprotein:7V-acetylneuraminic Chediak-Higashi syndrome Adriamycin acid transferase Animal model, beige mouse Cell kinetic recovery, rat, 737 Enzyme activity vs tumor burden, 3934 Basal lamina rat, 3103 Cyclophosphamide MÃ©tastases,1600 Immune complexes Mechanism of action, 395 Benz(a)anthracene, 7,12-dimethyl- Serum levels, dog, 3627 Cytolysis Estrogen, 2343 Lung neoplasms Bacillus Calmette-Cuerin, 1372 Hormonal control, 1612 DNA, proviral, 2316 Macrophages vs cancer cells, in Hormonal stimulation, mouse MÃ©tastases,2316 vitro, 1372 374 MÃ©tastases Mechanism of action, 1372 Hypothyroidism, 2336 DNA-RNA hybridization, 2316 Lectins Insulin, 2343 Neoplasm transplantation

DECEMBER 1980 4907 Subject Index to Volume 40

Mammary neoplasms (cont'd) Mammary neoplasms (cont'd) Melanoma(s) (cont'd) RNA, messenger, 362 X-rays DNA synthesis, 1414 Plasminogen activators Diethylstilbestrol, 3966 Cell culture Anchorage independent/ Mandelic acid, 3-methoxy-4-hydroxy- Mechanical/enzymatic disaggrega- dependent cells, 1812 Neural crest neoplasms tion, 2160 Progesterone Morphological study, 2160 Carcinoma(s), 1091 Urinary excretion, diagnosis 1995 Soft agar growth medium, 2160 Estrogens, 1091, 3232 Neuroblastoma Dexamethasone Ovariectomy, 1091 Urinary excretion, diagnosis Plasminogen activator, 2706 Prolactin 1995 DNA, double-stranded Dietary fats, 374 Isolation and characterization Estrogen, 3232 Mastocytoma 3792 Hormonal stimulation, mouse see also Sarcoma, mast cell DNA repair 374 Adriamycin Postreplication repair, mouse Receptors, hormone, 1674 Cytotoxic immune response, in 1867 Prostaglandin E2 vitro, 2748 DNA replication, 3792 Indomethacin, 3167 Matrix proteins Glycoproteins Receptors, hormone Wheat-germ agglutinin resistant vs Estradiol, 1la-methoxyethinyl- Bone neoplasms, 325 Procollagen non-resistant cell lines, 2580 3232 Classification scheme, 325 Guanosine Estrogen, 3232 Cytostasis, neoplastic vs normal Ovariectomy, 1050, 3232 Medulloblastoma Weibel-Palade bodies cells, mouse, 2147 Pregnant mouse, 3361 Hybridoma(s) Tamoxifen, 3232 Diagnosis, 2010 Antibodies, neoplasm, 2523 Retinoic acid Antigens, neoplasm, 2523 Benz(a)anthracene, 7,12-dimethyl- Meeting report Second International Workshop on Immune RNA 47 Chromosomes in Leukemia Lymphocyte-mediated tumor Binding proteins, 47 4826 cytolysis, 2377 Competitive inhibition, 47 Urea, iV-methyl-JV-nitroso-, 47 Third Annual Interdisciplinary Can Phase I clinical trial, 2377 cer Research Workshop Interferon Retinyl acetate Poly I-Poly C, 614 Tumorigenesis inhibition, 1140 Megestrol acetate MÃ©tastases RNA, transfer Breast neoplasms Organ selectivity, mouse, 2281 Methyltransferases, 417 Receptors, hormone, 2557 Phenylalanine, 5-S-cysteinyl-L-3,4- Somatomedin Melamine, hexamethyl- dihydroxy- Isolation and characterization Melamine, pentamethyl- Antitumor activity, in vitro 4368 L5178Y lymphoblast cells, 4489 Organ culture, mouse, 4368 2543 Drug uptake, 4489 Polypeptides, 4368 Receptors, hormone 4,4'-Stilbenediol, a,a'-diethyl- Melamine, pentamethyl- Glucocorticoids, 2174 Benz(a)anthracene, 7,12-dimethyl- Melamine, hexamethyl- Retinoids 1808 L5178Y lymphoblast cells, 4489 Cell differentiation, 2194 Suppressor cells Drug uptake, 4489 Hs939 melanoma cells, 3345 MIRW human melanoma cells IgG, 3477 Melanogenesis Immunization, rat, 3477 2194 Lymphocyte cytotoxicity, in vitro Retinoids Growth inhibition, in vitro, 1097 Phorbol myristate acetate, 3345 3477 Retinoic acid-binding protein Testosterone 1097 Uracil, 5-fluoro-, 2730 Melanoma(s) Melphalan Adenosine Tumor spheroids see Phenylalanine, L-p-(di-2- Cytostasis, neoplastic vs normal Spheroid attachment, 4631 chloroethylamino)- cells, mouse, 2147 Antibodies, cytotoxic Tumorilysin Alanine, 3-(3,4-dihydroxyphenyl)-, L- Characterization, 1255 Differential susceptibility, cell cy Urea, Af-methyl-JV-nitroso- DNA synthesis, 1414 cle, 56 Dosage schedule, rat, 235 Antibodies, neoplasm Ovarian neoplasms Receptors, hormone, 4628 Binding, cultured/freshly isolated Cell culture, 2743 Retinoids, 3095 neoplastic cells, 3602 Meningea! carcinomatasis Tamoxifen, 235 Antigens, neoplasm Urea hydrochloride, l-(4-amino-2- Tumor growth vs receptor levels, Immune serums, 2252 methyl-5-pyrimidinyl)methyl-3-(2- rat, 3232 Benz(a)anthracene, 7,12-dimethyl- chloroethyl)-3-nitroso- Virus, cytomegalo Animal model, albino guinea pig Bleomycin, 1341 Host resistance, mouse, 853 3652 Virus, murine mammary tumor 12-O-Tetradecanoylphorbol-13- Meningea! leukemia see Leukemia(s) Biology/virology/tumorigenicity, acetate, 155 five cell lines, 4232 Butyrophenone, 4-[4-(p- Menopause Hyperplastic alveolar nodules, chlorophenyl)-4- Breast neoplasms hydroxypiperidino]-4'- fluoro- mouse, 4232 Prolactin, 486

4908 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

3-Mercaptopicolinate MÃ©tastases(cont'd) Methionine see Picolinic acid, 3-mercapto- Lung neoplasms CCRF-HSB-2 cells 6-Mercaptopurine Chymostatin, 2539 Normal vs malignant cells, 634 F-136-3:-56 cells see Purine-6-thiol Elastinal, 2539 Leupeptin, 2539 Normal vs malignant cells, 634 Mesoporphyrin IX Lysosomal enzymes, 3281 Methotrexate L1210 cells Tumor enzyme activity, mouse Acetazolamide Cytotoxicity, 303 3281 Cerebrospinal fluid levels, human Photoactivation, 303 Mammary neoplasms 2184 Transport and binding, 303 Adenocarcinoma(s), 1588 Adenosine cyclic 3':5'- Mesothelioma Basal lamina, 1600 monophosphate DNA-RNA hybridization, 2316 Lung neoplasms Membrane transport, 2400 Ship-building workers, 3875 Phosphodiesterase inhibitors Bile salts Pleural neoplasms Growth inhibition, 1950 Drug uptake, hepatocytes, rat Nude mouse, 181 Plasminogen activator 1852 Transplantation, heterologous B16 melanoma cells, 288 Hepatotoxicity, 1852 181 Fibrinolytic activity, mouse, 288 Carcinoma, Ehrlich tumor Protease inhibitors Adenosine cyclic 3':5'- Mestranol Lung neoplasms, 2539 monophosphate, 2400 see Oral contraceptives Proteins MOPC 315 myeloma cells Platelet aggregation, 1217 Drug uptake, 4768 MÃ©tastases Sarcoma, Crocker 180 Liposome binding, 4768 Bacillus Calmette-Guerin Lysosomal enzymes, 3281 TEPC 15 myeloma cells Antigens, neoplasm, 4197 Tumor enzyme activity, mouse Drug uptake, 4768 Intralesional immunization, gui 3281 Liposome binding, 4768 nea pig, 4197 Uracil, 5-fluoro- 9L brain tumor cells Basal lamina Intraperitoneal administration Dose-response culture, 3202 Structural alterations, mouse 567 Dihydrofolate reducÃase 1600 Virus, cytomegalo Tissue drug levels, 1230 Blood platelets Host resistance, mouse, 853 DNA synthesis Mitogenic activity, 1217 Virus, murine mammary tumor Pharmacokinetics, mouse, 1230 Breast neoplasms DNA-RNA hybridization, 2316 Tissue drug levels, 1230 Hormone therapy, 2423 Hyperthermia Methane, azoxy- Carbohydrates Cystadenoma, mucinous, 256 Platelet aggregation, 1217 Colonic neoplasms Immunosuppression B16 melanoma cells Resection, intestinal, rat, 538 C57BL/6J spleen cells, 650 Lung neoplasms, 1645 Folinic acid, 650 Organ selectivity, mouse, 2281 Methanesulfon-jn-anisidide, 4'-(9- Hypoxanthine, 650 Tissue invasiveness variants, 1636 acridinylaminol- Thymidine, 650 Colonie neoplasms Liposomes CT26 carcinoma cells, 2142 Acridine derivatives Hyperthermia, local, 1388 CT36 carcinoma cells, 2142 Pharmacokinetics/phase I clinical trial, child, 4250 Preferential release, L1210 tumor, CT51 carcinoma cells, 2142 mouse, 1388 Growth characteristics/ Ouabain tumorigenicity, mouse cell lines Methanesulfonic acid, ethyl ester Transport/binding/ 2142 Escherichia coli polyglutamation, rat hepato Epidermoid carcinoma(s) Mutagenicity vs cytotoxicity cytes, 573 Animal model, chick embryo 3508 Oxidative phosphorylation 2300 Carcinoma, Ehrlich tumor, 3669 Hep-3 cells, 2310 Methanesulfonic acid, methyl ester Inhibitors, 3669 Plasminogen activator, 2300 Cell transformation, neoplastic Phenol, 2,4-dinitro- Ultraviolet rays, 582 Serial passage, chorioallantoic Carcinoma, Ehrlich tumor, 3669 membrane, chick embryo DNA repair Probenecid 2310 Ataxia telangiectasia, 984 Cerebrospinal fluid levels, human Fibrosarcoma(s) Ultraviolet rays, 582 2184 Immunological/nonimmunological Epithelium 1-Pyrophosphate, 5-phosphoribosyl factors, mice, 625 Trachea, rat, 2898 L1210 cells, 139 Ultraviolet rays, 625 Hepatocytes, rat Radiation, non-ionizing Glycoproteins Collagen gel-nylon mesh culture DNA synthesis, 1002 Wheat-germ agglutinin resistant 3259 Leukemia L1210 cells, 1002 vs non-resistant cell lines, 2580 Methanol, (methyl-OTVJV-azoxy)- Uptake enhancement, 1002 Hepatoma(s) Alcohol dehydrogenase Sarcoma, osteogenic Chymostatin, 2539 Carcinogenic metabolite, 4446 Solid tumor penetration, 3665 Elastinal, 2539 Sulfonic acid, p- Leupeptin, 2539 Methioninase chloromercuriphenyl- Lipids Homocysteine Transport/binding/ Platelet aggregation, 1217 Normal vs malignant cells, 634 polyglutamation, rat hepatocytes, 573

DECEMBER 1980 4909 Subject Index to Volume 40

Methotrexate (cont'd) 3-Methylcholanthrene Mitomycin C (cont'd) Thymidine see Cholanthrene, 3-methyl- LoVo cells Drug rescue, 1824 5-Methylchrysene Cell cycle kinetics, 1973 Furine synthesis, 1824 see Chrysene, 5-methyl- DNA How, 1973 MOPC-315 myeloma cells 3-Methoxy-4-hydroxymandelic acid Methylglyoxal bis(guanylhydrazone) Antitumor cytotoxicity, spleen see Guanidine, 1,-1'-(methylethanedi- see Mandelic acid, 3-methoxy-4- cells, 4565 hydroxy- ylidenedinitriloldi- Coenzyme Q,0 Membrane potential difference, O6-Methylguanine liver, rat, 1663 3-Methoxy-4-hydroxyphenylacetic acid see Guanine, O"-methyl- see Acetic acid, 3-methoxy-4- Potassium, 1663 hydroxyphenyl- Colonie neoplasms AP-Methylguanosine Cell cycle kinetics, 1973 8-Methoxypsoralen see Guanosine, JV-methyl- DNA How, 1973 DNA repair DL-a-Methylornithine Hyperthermia Photoactivation, 696 see Ornithine, a-methyl-, DL- Heat sensitivity, 1165 WI-38 fibroblast cells, 696 LoVo cells, 1165 Xeroderma pigmentosum cells 4-Methylphorbol-12,13-didecanoate Hypoxia 696 Insulin EMT6 mouse mammary tumor Glucose, 3827 cells, 2356 JV-Methyl-4-aminoazobenzene Pancreatic islets, rat, 3827 Sarcoma 180 cells, 2356 see Azobenzene, N-methyl- Leukemia L1210 Methyltransferases 3'-Methyl-4-dimethylaminoazobenzene Vaccines, 3839 Adenocarcinoma(s) Lymphocytes see Benzenamine, JV,JV-dimethyl- Benz(a)anthracene, 9,10-dimethyl- Cytogenetics, human, 477 4-((3-methylphenyl)azo)- 417 Sister chromatid exchange, 477 RNA, transfer l-Methyl-3-isobutylxanthine Adenocarcinoma(s), 417 MMNG see Xanthine, l-methyl-3-isobutyl- Guanosine, AP-methyl-, 417 see Guanidine, Tv'-methyl-N'-nitro-A'- nitroso- Methyl methanesulfonate Mammary neoplasms, 417 see Methanesulfonic acid, methyl es Mevalonic acid Molybdate ion ter Cholesterol Receptors, hormone Hepatoma(s), 4717 Prostate gland, human, 2234 jV-Methyl-JV-nitro-TV-nitrosoguanidine Coenzyme A reducÃase,3-hydroxy-3- see Guanidine, N-methyl-TV-nitro-JV Monocytes -nitroso- methylglutaryl Adenosine cyclic 3':5'- Hepatoma(s), 4717 monophosphate 4-(JV-methyl-JV-nitrosoamino)-l-(3- Mezereine Phosphodiesterase, 1955 pyridyl)-l-butanone C3H/10T1/2 cells Xanthine, l-methyl-3-isobutyl- see 1-Butanone, 4-(JV-methyl-.N- Cytidine, 5-aza, 334 Cycloheximide, 1955 nitrosamino)-1 -(3-pyridyl)- /Sj-Microglobulin Monooxygenase 1-Methyl-l-nitrosourea Immune serums Cytochrome P-450 see Urea, AT-methyl-JV-nitroso- Indirect rosette microassay, 2252 Hormone regulation, 2486 Misonidazole Monosialoganglioside Methyl sulfoxide see also 2-Propanol, l-(2-nitro-l- Binding, normal/neoplastic thymo- HL-60 cells imidazolyl)-3-methoxy- cytes, mouse, 2808 Granulocytes, 1469 Alkylating agents Morpholine, 2,6-dimethyl-JV-nitroso- Neoplasms, mouse, 4165 Ames test Synergistic activity, 4165 Methyladenosine phosphorylase Aryl hydrocarbon hydroxylase CCRF-CEM cells Mitochondria 67 Polyamine metabolism, 4178 Calcium transport Carcinogenic metabolites, hamster K562 leukemia cells Cell transformation, neoplastic 67 Polyamine metabolism, 4178 221 AT-Nitrosobis(2-oxopropyl)amine MOLT-4 cells Leukemia(s), 221 67 Polyamine metabolism, 4178 Guanidine Morpholine, JV-nitroso- Ultrastructural study, 1054 Raji cells Ames test Hepatoma, Novikoff Polyamine metabolism, 4178 Liver microsomes, human/rat Enzyme activity, 1486 119 Normal/neoplastic liver, rat Cytochrome P-450-dependent mo- Methylazoxymethanol 1486 see Methanol, (methyl-OivW-azoxy)- nooxygenases Mitomycin C Intel-individual differences, 119 7-Methylbenz(a)anthracene Bladder neoplasms Ethylene, chloro- Papilloma(s) Formamide, JV-[4-(5-nitro-2- Carcinogenic metabolites, 119 Mouse, 1981 furyl)-2-thiazolyl]-, 261 Glucose-6-phosphatase Skin neoplasms Intravesical administration, mouse Subpopulations, hepatocytes, rat Dihydrodiols/diol-epoxides, 1981 261 459

4910 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Morpholine, JV-nitroso-(cont'd) Neoplasm diagnosis Nervous system neoplasms Glutathione Carcinoembryonic antigen Toxoplasma gondii Hyperplastic cell islands, liver, rat Antigen-antibody complexes, 497 Inflammatory response, rat/ 490 Ovarian neoplasms, 502 mouse, 1240 Ultrastructural/cytochemical study IgG Tumor inhibition, rat/mouse Subpopulations, hepatocytes, rat Antigen-antibody complexes, 497 1240 459 Urea, 1-ethyl-1-nitroso-, 1240 Neoplasm growth Cyclophosphamide Mouse, inbred strains 3924A hepatoma cells, 2179 Neural crest neoplasms Standardized nomenclature Computerized measurement Acetic acid, 3-methoxy-4- Origins, characteristics, strain dis 2179 tribution of alÃeles,2083 hydroxyphenyl- Urinary excretion, diagnosis Neoplasm transplantation 1995 Mandelic acid, 3-methoxy-4- Mutations C3H/He mammary carcinoma cells 12-O-Tetradecanoylphorbol-13- hydroxy- Growth characteristics, lung, acetate mouse, in vivo, 3495 Urinary excretion, diagnosis Ultraviolet rays, 3245 Hep-3 cells 1995 Animal model, chick embryo Myeloma, MOPC-21 2300 Neuroblastoma(s) DNA polymerases MÃ©tastases,2300 Inhibition factor, mouse, 758 Ribonuclease Fibrosarcoma(s) Seminal plasma, bovine, 3740 Cross-protection, mouse, 1036 Myeloma(s) Soft agar culture technique Methotrexate Immunization, 1036 Bone marrow/lymph node/solid Drug uptake. 4768 Ultraviolet rays, 625 tumor, human, 3591 Hyperthermia, localized NAD Antitumor activity, mouse, 26 see Nicotinamide adenine dinucleo- Fibrosarcoma(s), 26 Neuroepithelioma 1-Butanone, 4-(JV-methyl-JV- tide Immunization Bacillus Calmette-Guerin, 1036 nitrosamino)-1-(3-pyridyl)- NADPH Carcinogenicity, rat, 298 see Nicotinamide adenine dinucleo- Keratoacanthomas Nicotine, 1'-demethyl-1'-nitroso- tide phosphate Hair follicle cycle, nude mouse 1668 Carcinogenicity, rat, 298 NADPH oxidase Immunity, cellular, 1668 12-O-Tetradecanoylphorbol-13- Mammary neoplasms Nickel subsulfide acetate RNA, messenger, 362 Cell transformation, neoplastic HL-60 cells, 1469 Tumor growth, mouse, in vivo Embryo cells, hamster, 2688 Nafoxidine 3977 Ovary cells, hamster, 2688 Receptors, hormone Prostatic neoplasms Phagocytosis, 2688 Estradiol, 3821 Hormone dependency, rat, 3547 Uterus, guinea pig, 3821 3551 Nicotinamide adenine dinucleotide Radiotherapy Guanidine, N-methyl-N'-nitro-TV- 1-Naphthylamine Antitumor activity, mouse, 26 nitroso- Bladder neoplasms Fibrosarcoma(s), 26 Carcinogenicity, dog, 3537 3T3 cells, 1797 2,6,10,14-Tetramethylpentadecane Rate of degradation, 1797 Nasal cavity neoplasms Chondrosarcoma, 2229 Lymphocytes Benzylamine, JV-methyl-AT-nitroso- Lymphosarcoma, 2229 DNA-damaging agents, direct/ Target tissues, 1921 Plasmacytoma, 2229 indirect, 1803 Formaldehyde Vascularization Carcinogenesis, mouse/rat, 3398 Growth, nude mouse, 4509 Nicotinamide adenine dinucleotide Propylamine, 2,2'-dioxomethyl-Ar- Virus, Friend phosphate nitroso- Immune response, rat, 448 Bleomycin Carcinogenicity, hamster, Syrian Virus, Gross DNA chain breakage, in vitro/in 3585 Immune response, rat, 448 vivo, 2051 Liver microsomes, rat, 2051 National Cancer Institute Virus, SV40 Nicotine, r-demethyl-l'-nitroso- Scientific conferences, 2617 Cell transformation, viral, 1380 Neuroepithelioma Neocarzinostatin HeLa-S3 cells Neoplasms Carcinogenicity, rat, 298 Whole body autoradiography Caffeine, 3786 Soft agar Biodistribution, mouse, 3518 Cell cycle, 2405 Cell culture, 4151 Cell cycle block, 3786 Niridazole Dibutyryl cyclic AMP, 3786 Nitroreductase DNA repair, 2405 Neoplasms, heterologous Mutagenicity, 4599 DNA, single strand, 2405 Vascularization Salmonella typhimurium Theophylline, 3786 Growth, nude mouse, 4509 Mutagenicity, 4599

DECEMBER 1980 4911 Subject Index to Volume 40

Nitrenium ions jV-Nitrosomorpholine Oleic acid (cont'd) Furine N-oxides see Morpholine, JV-nitroso- Complement-mediated cytolysis Oncogenic/nononcogenic deriva JV-Nitrosonornicotine 1084 tives, 1475 see Nicotine, r-demethyl-l'-nitroso- Oligodendroglioma Oxidation-reduction reactivity Weibel-Palade bodies 1475 Nitrosoureas V-79-4 Chinese hamster lung cells Diagnosis, 2010 N-[4-(5-nitro-2-furyl)-2- Mutagenicity/cytotoxicity, 2719 Oligosaccharides thiazolyl]formamide DNA a-Fetoprotein see Formamide, 7V-[4-(5-nitro-2- V-79-4 Chinese hamster lung cells Ascites fluid, human, 4282 furyl)-2-thiazolyl]- 2719 Isolation and characterization l-(2-Nitro-l-iimdazolyl)-3-methoxy-2- DNA repair 4282 L1210 cells, 771 propanol Oncogenic viruses see 2-Propanol, l-(2-nitro-l- Radiation, ionizing, 771 Leukemia(s) imidazolyl)-3-methoxy- Radiation, ionizing Review, 3405 Synergistic effects, 771 Lymphoma(s) Nitrogen mustard Review, 3405 9L brain tumor cells Nogalamycin Analogs DNA damage, 3186 Oral contraceptives Cytotoxicity vs cell cycle, 3437 Diethylamine, .N-nitroso- 4-Nitroquinoline 1-oxide CHO cells Hepatocarcinogenesis, rat, 3680 see Quinoline, 4-nitro-, 1-oxide Cytotoxicity vs cell cycle, 3437 Non-Hodgkin's lymphoma Nitroreductase Ornithine decarboxylase Niridazole see Lymphoma(s) Bladder neoplasms Mutagenicity, 4599 Formamide, N-[4-(5-nitro-2- Noradrenaline furyl)-2-thiazolyl]-, 1897 see Norepinephrine Nitrosamines Erythroleukemia Angiosarcoma Norepinephrine Cell differentiation induction Carcinogenicity, guinea pig, 1879 Adenocarcinoma(s) 1727 Chinese hamster V79 cells Antitumor activity, 4320 Formamide, JV-[4-(5-nitro-2-furyl)-2- Cell-mediated assay, 406 Hepatoma(s) thiazolyl]- Mutagenic metabolites, 406 Chemotherapy, 481 Enzyme activity, mouse, 1897 Hepatocytes Hemodynamics, rat, 481 Guanidine, l,-l '-(methylethanedi- Mutagenic metabolites, 406 ylidenedinitrilojdi- Microsomal oxidative dealkylation Norethynodrel Intestinal mucosa, rat, 2330 Aldehyde assay, 3241 see Oral contraceptives Hepatocarcinogenesis jV-Nitrosobis(2-hydroxypropyl)amine Normal/regenerating/neoplastic see Dipropylamine, 2,2'-dihydroxy-Ar liver, rat, 4373 -nitroso- Nucleic acid synthesis Hyperthermia Lung neoplasms Polyamines, 432 i\-Nitrosobis(2-oxopropyl)amine Adenocarcinoma(s), 2295 Indomethacin see Dipropylamine, 2,2'-dioxo-JV- Carcinoma(s), 2295 Skin neoplasms, 308 nitroso- Epidermoid carcinoma(s), 2295 Puromycin Cell survival, 432 JV-Nitrosodiethylamine Rat-1 fibroblasts see Diethylamine, Af-nitroso- Nucleoside triphosphatase RNA Cell transformation, viral, 604 yV-Nitrosomethyl-2-hydroxypropylamine Acetamide, thio-, 75 Putrescine, 604 see Propylamine, 2-hydroxymethyl- Virus, Rous sarcoma, 604 N-nitroso- Nucleosides Retinoic acid 12-O-Tetradecanoylphorbol-13- jV-Nitrosomethyl(2-oxopropyl)amine Benzaldehyde see Propylamine, 2,2'-dioxo-methyl- Metabolism, transformed fibrob- acetate, 2367 Retinoic acid, 5,6-dihydro- lasts, 2574 7V-nitroso- 12-O-Tetradecanoylphorbol-13- DNA repair jV-Nitrosomethylbenzy lamine Age, sex, diet factors, rat, 3719 acetate, 2367 Retinoic acid, 5,6-epoxy- see Benzylamine, AT-methyl-JV- 5'-Nucleotidase 12-O-Tetradecanoylphorbol-13- nitroso- Adenine, 9-ÃŸ-D-arabinofuranosyl- acetate, 2367 BHK 21/C13 hamster cells, 4123 Nitrosotnethylethylamine derivatives Adenine, 9-/3-D-arabinofuranosyl, 5'- Skin neoplasms Deuterium labeling Papilloma(s), 308 Carcinogenicity, rat, 19 monophosphate 12-O-Tetradecanoylphorbol-13- Esophageal neoplasms BHK 21/C13 hamster cells, 4123 acetate Papilloma(s), 19 Occupational diseases Enzyme induction, mouse skin Hepatoma(s) Mesothelioma 308 Carcinogenicity, rat, 19 Ship-building workers, 3875 Epidermal cells, mouse, 2653 Epidermis, mouse, in vitro/in vivo Nitrosomethylurea Oleic acid 4013 see Urea, JV-methyl-JV-nitroso- Morris hepatoma 7777 cells Skin neoplasms, 308

4912 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Ornithine decarboxylase (cont'd) Ovariectomy (cont'd) Pancreatic neoplasms(cont'd) Thiazole, 2-amino-4-(5-nitro-2-furyl)- Mammary neoplasms Transplantation, heterologous Enzyme activity, mouse, 1897 Enzyme activity, tumor/uterus, Amylase activity, nude mouse/ Retinoic acid, 13-c/s-, 1897 rat, 3158 cultured cells, 592 Receptors, hormone, 3232 Ornithine, a-methyl-, DL- Papilloma(s) Brain neoplasms, 1961 Ultrastructure, 3112 4628 Benzo(e)pyrene Dihydrodiols/diol-epoxides, 1981 Polyamines Progesterone 9L cells, 1961 Mammary neoplasms, 1091 Chrysene Cytostasis, 1961 Receptors, hormone Dihydrodiols/diol-epoxides, 1981 Mammary neoplasms, 1050 Dibenz(a,c)anthracene Dihydrodiols/diol-epoxides, 1981 Orotidine 5'-monophosphate decarboxy 1612 Dibenz(a,h)anthracene lase Oxidases, mixed-function Pyrazofurin Dihydrodiols/diol-epoxides, 1981 Griseofulvin Cell cycle, 2869 Esophageal neoplasms Hyperplastic liver nodules, mouse 3924A hepatoma cells, 2869 Nitrosomethylethylamine deriva 2568 tives, 19 Osteosarcoma Oxidation-reduction reactivity 7-Methylbenz(a)anthracene see Sarcoma, osteogenic Furine Af-oxides Dihydrodiols/diol-epoxides, 1981 Pyloric ulcer Ouabain Nitrenium ions, 1475 Anthracylic antibiotics W/Wv and SI/SID genotype Oxidoreductase enzymes mice, 3392 Cardiotoxicity, mechanism, 4581 HC-252 hepatocellular carcinoma C3H/10T1/2 CL8 mouse fibrob- Skin neoplasms cells Ornithine decarboxylase, 308 last cells, 4581 Cell proliferation vs enzyme ac Prostaglandins, 308 Methotrexate tivity, 4677 Transport/binding/ Parathyroid neoplasms polyglutamation, rat hepato- Oxygen Hyperplastic/neoplastic parathyroid, cytes, 573 Ascites tumor cells human/bovine Electrophoretic mobility, 4751 Soft-agar culture, 3694 Ovarian neoplasms Adriamycin Oxypurinol Peanut agglutinin Cytotoxicity in vitro vs in vivo, Uracil, 5-fluoro- Adenocarcinoma(s) human, 4109 Toxicity reduction, bone marrow Sialoglycoprotein, 1873 Metabolites, 4109 cells, in vivo/in vitro, 1885 Solid vs ascites form, rat, 1873 T-Antigen Antineoplastic agents P388D, cells Malignant effusion/abdominal Epidermal growth factor Sialoglycoprotein, 1873 washings, human, 2743 Phagocytosis, 1028 Pectin Carcinoembryonic antigen 12-O-Tetradecanoylphorbol-13- Colonie neoplasms IgG, 502 acetate Tumor incidence/histopathology, Cell culture Phagocytosis, 1028 rat, 2661 Malignant effusion/abdominal washings, human, 2743 Palmitic acid Pentadecane, 2,6,10,14-tetramethyl- Bladder tumor cells Carcinoma, Ehrlich tumor Neoplasm transplantation Ascites fluid, human, 4495 Metabolism, 2447 Chondrosarcoma, 2229 Blastogenic response, 4495 Lymphosarcoma, 2229 HEp-2 human epithelioid cells Pancreatic neoplasms Adenocarcinoma(s) Plasmacytoma, 2229 Ascites fluid, human, 4495 Dipropylamine, 2,2'-dioxo-7V- Plasmacytoma Blastogenic response, 4495 nitroso-, 67 Transplantation, homologous Chromosome aberrations Morpholine, 2,6-dimethyl-N- 579 Karyotyping, 4512 nitroso-, 67 Lymphocyte-inhibitory factor Pentamethylmelamine Isolation and characterization Carcinoma(s) Serine, diazoacetate (ester), 592 Hexamethylmelamine 1842 Dipropylamine, 2,2'-dioxo-N-nitroso- Pharmacokinetics, mouse, 2762 B-Lymphocytes Carcinogenicity, hamster, Syrian Plasmacytoma, 2762 Ascites fluid, human, 4495 3585 Blastogenic response, 4495 Peptide hydrolases T-Lymphocytes DNA synthesis Fibroblasts Cell transformation, neoplastic Ascites fluid, human, 4495 Medium change response, chicken 3443 1753 Blastogenic response, 4495 Morpholine, 7V-nitroso-2,6-dimethyl- Oligodendroglioma Binding sites, pancreas, hamster Peroxidase Ascites fluid, human, 4495 2245 Mammary neoplasms Blastogenic response, 4495 Propylamine, 2,2'-dioxomethyl-N- Estrogens, 3158 Ovariectomy nitroso- Phagocytosis Adrenal gland neoplasms Carcinogenicity, hamster, Syrian Cell transformation, neoplastic Spontaneous tumors, aged mouse 3585 Nickel subsulfide, 2688 3570 Sialyltransferase Epidermal growth factor Virus, type C, 3570 Tumor burden, diagnosis, 1300 Macrophages, mouse, 1028

DECEMBER 1980 4913 Subject Index to Volume 40

Phagocytosis (cont'd) L-Phenylalanine mustard (cont'd) Phosphodiesterase (cont'd) P388D, cells, 1028 Cyclophosphamide Enzyme activity, human, 1955 12-O-Tetradecanoylphorbol-13- Chromosome count, rodent tu Monocytes, 1955 acetate mors, 830 Guanosine cyclic 3':5'- Macrophages, mouse, 1028 Cross-resistance, rodent tumors monophosphate P388D, cells, 1028 830 Blastogenesis, lymphocytes, hu 1,10-PhenanthroIine Gas chromatography-mass spec- man, 379 Carcinoma, Ehrlich ascites trometry assay Xanthine, l-methyl-3-isobutyl- Cell proliferation, in vitro, 4092 Plasma, human, 2268 Enzyme activity, human, 1955 DNA synthesis, 4092 Phorbol-12,13-didecanoate Phospholipids PhÃ©nobarbital T51B rat liver cells Hepatoma(s) see Barbituric acid, 5-ethyl-5-phenyl- DNA synthesis, 4541 Benzenamine, N,N-dimethy\- 4-((3-methylphenyl)azo)-, 909 Phenol, (l,l-dimethyl)-4-methoxy- Phorbol 12,13-dibutyrate Phorbol 12-myristate 13-acetate 12-O-Tetradecanoylphorbol-13- Benzo(a)pyrene acetate Metabolites, 2824 Binding, brain tissue, mouse 3635 Lymphocytes, bovine, 776 Liver microsomes Oxygen-dependent synthesis, 776 Anticarcinogenic activity, mouse Phorbol-12,13-benzoate 2824 3BM-78 cells N-(Phosphonacetyl)-L-aspartate Phenolic compounds Specific esterase inhibition, mouse see also Aspartic acid, 7V-(phosphonacetyl)- Anticarcinogenic activity, mouse 866 2820 T51B rat liver cells Uridine Phase I clinical trial, 2938 Phenol, 2,4-dinitro- Calcium, 4541 Hypoxanthine-guanine phos- Serum, humans, 2938 Methotrexate Carcinoma, Ehrlich tumor, 3669 phoribosyltransferase Phosphoramide mustard Intercellular communication, epi Guanosine Phenolic compounds dermal cells/fibroblasts, mouse Adduct formation, 4138 Phenol, (1,1-dimethyl)-4-methoxy- 2935 Guanosine, deoxy- Anticarcinogenic activity, mouse 12-O-Tetradecanoylphorbol-13- Adduct formation, 4138 2820 acetate Stomach neoplasms Hep G: human hepatoma cells 5-Phosphoribosyl-l-pyrophosphate see 1-Pyrophosphate, 5- Anticarcinogenic activity, mouse 4433 2820 Epidermal cells, human/guinea phosphoribosyl Phenylalanine, 5-S-cysteinyl-L-3,4- pig, 4433 Phosphoric monoester hydrolase dihydroxy- Fibroblasts, hamster/rat/chick/ Prostatic neoplasms Carcinoma(s) mouse/human, 4433 Isolation and characterization, rat Antitumor activity, in vitro 1245 2543 Phorbol esters Phosphorodiamidic acid, JVv/V-di-(2- Melanoma(s) Carcinogenicity, skin, mouse chloroethyl)- Antitumor activity, in vitro Inflammatory response, mouse Antineoplastic agents 2543 2273 Plasma levels, human, 4734 Neuroblastoma Cell nucleus Phosphorothioic acid, S-2-(3- Antitumor activity, in vitro Site of action, 1066 aminopropylamino)ethyl- 2543 Swiss 3T3 mouse cells, 1066 Chick embryo fibroblasts In vivo/in vitro analysis Phenylalanine, I ,-p-(rii-2- chloro- Absorption kinetics, mouse/rat/ ethylamino)- Inflammatory activity, 339 Structure-activity relationships rabbit, 1519 Amino acids Chemotherapy DNA cross-linking, 1169 339 Toxicity resistance, 1519 2-Carboxylic acid, DL-/3-2- Radiotherapy aminobicyclo[2,2,IJheptane- Phorbol, 4-O-methyl-12-O- tetradecanoyl- Toxicity resistance, 1519 Drug transport, 1144 T51B rat liver cells Picolinic acid, 3-mercapto- Sensitive/resistant cells, 1144 Calcium, 4541 Cell cycle DNA synthesis, 4541 Gluconeogenesis RPMI 6410 cells, 1169 Sarcoma(s), 1699 Leukemia L1210 cells Piperazine, 1,4-dinitroso- Drug transport, 1144 Phorbol-12-myristate-13-acetate Heterocyclic nitrosamines Sensitive/resistant cells, 1144 see 12-O-Tetradecanoylphorbol-13- Transplacental/tranlactational L-Phenylalanine mustard acetate carcinogenesis, mouse, 2925 see also Phenylalanine, L-p-(di-2- Piperazine, ./V-methyl-JV-nitroso- chloroethylamino)- Phosphodiesterase Adenosine cyclic 3':5'- Ames test Carcinosarcoma, Walker 256 Liver microsomes, human/rat Cyclophosphamide, 830 monophosphate 119 Chromosome aberrations Blastogenesis, lymphocytes, hu Cytochrome P-450-dependent mo- Therapy-induced malignancy man, 379 nooxygenases 4076 P388D, cells, 1955 Interindividual differences, 119

4914 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Piperazine, ./V-methyl-TV-nitroso- Plasminogen activators (cont'd) Platinum(II), diamminedichloro-, da (cont'd) Human breast cancer cells (cont'd) Ethylene, chloro- HBL-100 human breast cells Second-generation platinum ana Carcinogenic metabolites, 119 4385 logs, 3318 MCG-T14 mouse mammary tumor Piperidine, 3-chloronitroso- Hyperthermia cells Cytotoxicity enhancement, 1136 Carcinogenicity, Fischer rat, 3325 Mitogenic activity, 4385 DNA cross-linking, 1136 Piperidine, 4-chloronitroso- 3T3 cells Heat sensitivity, 1165 Carcinogenicity, Fischer rat, 3325 Retinoic acid, 3089 LoVo cells, 1165 Dexamethasone Piperidine, 3,4-dichloronitroso- Pleural neoplasms Neoplastic cells/embryonic cells Carcinogenicity, Fischer rat, 3325 Mesothelioma 2706 Nude mouse, 181 Pituitary gland Indomethacin Transplantation, heterologous Lymphoma(s) Prostaglandin biosynthesis, 849 181 Estrogen, 2437 Lung neoplasms Growth in vivo, Nb rat, 2437 Isolation and characterization Poly A 841 RNA Placenta Urokinase, 841 Aged/neonatal/neoplastic/ Alkaline phosphatase Mammary neoplasms regenerating liver, rat, 1449 Antibody binding, normal/ Anchorage independent/ Half-life of decay, rat liver, 1449 neoplastic tissue, human, 4064 dependent cells, 1812 Poly I-Poly C Horseradish peroxidase, 4064 Neoplasm metastasis Interferon Anemia-inducing factor B16 melanoma cells, 288 Antitumor activity, mouse, 614 Isolation and characterization Fibrinolytic activity, mouse, 288 Ml mouse leukemia cells, 2919 Retinoic acid 1686 Melanoma(s), 614 Neoplasm diagnosis, 1686 Normal/neoplastic cells, human 4817 Poly(2'-O-methylcytidylate) Plasma membrane Retinoids see Cytidylic acid, poly(2'-O- Normal/neoplastic cells, human Glycoproteins 4817 methyl)- Radioactive labeling, 1550 12-O-Tetradecanoylphorbol-13- Mammary neoplasms 3'-Polyadenylate Cell transformation, neoplastic acetate HeLa cells, 849 see Poly A 2383 Erythroleukemia, 3369 Prostaglandin biosynthesis, 849 Urokinase Polyamines Plasmacytoma Anti-urokinase antibody, 933 Astrocytoma Cyclophosphamide Cerebrospinal fluid, human, 3293 Dose schedule, mouse, 2135 Molecular species, normal/ neoplastic/embryonic human Brain neoplasms Immune response, mouse, 2135 Ornithine, a-methyl-DL-, 1961 Pentad ecane, 2,6,10,14-tetramethyl cells, 933 L1210 leukemia cells Transplantation, homologous Platelet aggregation Guanidine, 1,- 579, 2229 Carbohydrates l'-((methylethanediylidene)dini- Pentamethylmelamine Cell membrane, 1217 trilo)-, di-, 4533 Hexamethylmelamine, 2762 Neoplasm metastasis, 1217 Erythroleukemia Uracil, 5-fluoro- Lipids Cell differentiation induction Immune response, mouse, 2790 Cell membrane, 1217 1727 Neoplasm metastasis, 1217 Glioblastoma multiforme Proteins Cerebrospinal fluid, human, 3293 Plasminogen Cell membrane, 1217 Guanidine, 1,- 12-O-Tetradecanolyphorbol-13- Neoplasm metastasis, 1217 1'-(methylethanediylidene- acetate c/s-Platinum dinitrilo)bis- Macrophages, peritoneum, mouse Ovarian neoplasms Intestinal mucosa, rat, 2330 2273 Cell culture, 2743 Hyperthermia Chinese hamster ovary cells, 432 Platinum(II) chloroammines Cytotoxicity, 432 Chinese hamster ovary cells Plasminogen activators Ornithine decarboxylase, 432 Cytotoxcity, 1463 Carcinoma, epidermoid Ornithine, a-methyl-DL- DNA binding, 1463 9L cells, 1961 MÃ©tastases,2300 Mutation-induction curves, 1463 Serial passage, chorioallantoic Cytostasis, 1961 membrane, chick embryo Platinum(II), diamminedichloro-, cis 2310 MOPC 104E myeloma cells Cell transformation, neoplastic IgM, 2372 Polycyclic hydrocarbons Fibrinolytic activity, hamster cells Plateau phase, mouse, 2372 Ames test, 642 1438 DNA, PM-2 Benzo(a)pyrene 4,5-oxide Semisolid agar growth, hamster Binding/conformational changes Toxication/detoxication, 101 cells, 1438 3313, 3318 5,6-Benzoflavone

DECEMBER 1980 4915 Subject Index to Volume 40

Polycyclic hydrocarbons (cont'd) Progestagen Propionibacterium acnes Inhibition of carcinogenesis, 2774 Receptors, hormone Line 10 hepatocarcinoma cells Molecular structure, 2774 Hormonal control, breast cancer Tumor growth, guinea pig, 3211 7,8-Benzoflavone 1750 Hepatoma(s) Inhibition of carcinogenesis, 2774 Progesterone Tumor growth, guinea pig, 3211 Molecular structure, 2774 Breast neoplasms Propylamine, 2,2'-dioxomethyl-N- Dihydrodiols/diol-epoxides Receptors, hormone, 1750, 3357 nitroso- Bay-region theory carcinogenesis Mammary neoplasms 1981 Nasal cavity neoplasms Diol-epoxides/tetrahydroepoxides Carcinoma(s), 1091 Carcinogenicity, hamster Estrogens, 1091, 3232 3585 Mutagenesis, 1985 Ovariectomy, 1091 Liver microsomes, rat/mouse Pancreatic neoplasms Receptors, hormone Carcinogenic metabolites, 1742 Carcinogenicity, hamster Breast neoplasms, 2557 3585 Mutagenic vs carcinogenic activity Dextran-coated charcoal vs su 642 crose gradient analyses, 4127 Propylamine, 2-hydroxymethyl-N- Nicotinamide adenine dinucleotide nitroso- Lymphocytes, 1803 Estrogen sulfotransferase, 1360 Prostate gland, human, 2234 Ames test Polyethylene glycol 6000 V79 hamster liver cells, 3463 MOPC-315 myeloma cells Progestins Breast neoplasms Prostaglandin E, Antitumor cytotoxicity, spleen Adenosine cyclic 3':5'- Receptors, hormone, 2557 cells, 4565 monophosphate Therapeutic response, 2557 Granulocyte-macrophage colony- Prolactin Polyinosinic-polycytidylic acid forming units, 1223 see Poly I-Poly C Breast neoplasms Guanosine cyclic 3':5'- Lactalbumin, 486 monophosphate Polypeptides Menopause, 486 Kidney neoplasms Granulocyte-macrophage colony- Normal vs neoplastic tissue, in forming units, 1223 Cell transformation, neoplastic vitro, 486 3728 Leukemia, myelocytic Broparestrol Proliferation, human cells, 1223 Polyribosomes Mammary neoplasms, 1674 Antigens, neoplasm Dexamethasone Prostaglandin !â€¢;.. Neoplastic/normal/regenerating Butyrophenone, 4-(4-(p- Embryo fibroblast cells liver, rat, 1367 chlorophenyl)-4- hydroxy- Lymphocyte-stimulated produc Nucleolar proteins, 1367 piperidino)-4'-fluoro-, 1863 tion, rat, 3167 SaD2 fibrosarcoma cells Lymphoma(s) Epithelial cells Lymphocyte-stimulated produc Tumor suppression, mouse, 1501 Cell proliferation, Nb rat, 2433 Serratia marcescens Mammary neoplasms tion, rat, 3167 Tumor suppression, mouse, 1501 Dietary fats, 374 Prostaglandin endoperoxide synthetase Estrogen, 3232 Benzidine Potassium Binding, renal medulla microx- Mitomycin C Hormonal stimulation, mouse Coenzyme Q,0, 1663 374 omes, rabbit, 2839 Uracil, 5-fluoro Receptors, hormone, 1674 Metabolism, 2839 Formamide, N-[4-(5-nitro-2-furyl)-2- Coenzyme Q,0, 1663 Receptors, hormone Broparestrol, 1674 thiazolyl]- Pregnenolone-loa-carbonitrile Urea, N-methyl-Af-nitroso- Carcinogenic metabolites, rabbit/ Epoxide hydrolase Carcinogenicity, rat, 3095 ram, 114 Lymphocytes, fresh/mitogen- Kidney microsomes, rabbit, 114 stimulated, 2552 Pronase Seminal vesicle microsomes, ram Serratia marcescens 114 Pristane SaD2 fibrosarcoma cells, 1501 see Pentadecane, 2,6,10,14- Prostaglandin F2a tetramethyl- Propanediol Adenosine cyclic 3':5'- Ames test monophosphate Probenecid Mutagenic metabolites, 276 Granulocyte-macrophage colony- Methotrexate Tetramethoxypropane forming units, 1223 Cerebrospinal fluid levels, human Mutagenic metabolites, 276 Guanosine cyclic 3':5'- 2184 2-Propanol, l-(2-nitro-l-imidazolyl)-3- monophosphate Granulocyte-macrophage colony- Procollagen methoxy- Bone neoplasms forming units, 1223 C3H mouse/Chinese hamster ovary Matrix proteins, 325 Leukemia, myelocytic Sarcoma, Ewing's, 325 cells, 2165 Proliferation, human cells, 1223 Mechanism of action, 2165 Sarcoma, osteogenic, 325 Nitroreduction, 2165 Prostaglandins Collagenase Indomethacin CCL 137 lung fibroblast cells l-Propargyl-5-chlororpyrimidin-2-one Synthesis inhibitors, 308 4722 Vincristine Skin neoplasms Matrix proteins Cell cycle kinetics, 2069 Papilloma(s), 308 Classification scheme, 325 NHIK 3025 cells, 2069 12-O-Tetradecanoylphorbol-13- acetate

4916 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Prostaglandins (cont'd) Protein kinases (cont'd) Purine nucleotides HeLa cells, 849 Hepatocarcinogenesis Deoxyribonucleoside triphosphates Plasminogen activators, 849 Normal/regenerating/neoplastic Normal/regenerating/neoplastic/ liver, rat, 4373 neonatal liver, rat, 1286 Hydrazine, 1,2-dimethyl- Prostaglandins E Purine JV-oxides Carcinogenesis, colonie mucosa, Cell differentiation Nitrenium ions rat, 4589 Ml myeloid leukemia cells, 3387 Oncogenic/nononcogenic deriva Leukemia, lymphoblastic HL-60 cells tives, 1475 Colony formation, 1858 Lymphocytes, normal/neoplastic Oxidation-reduction reactivity 2714 KG-1 cells 1475 Colony formation, 1858 Purine-6-thiol Colonie neoplasms Proteinase K Adenosine cyclic 3':5'- L1210 cells DNA monophosphate, 2529 Chlorozotocin, 50 Bacillus subtilis, 4381 Leukemia, myelocytic Urea, l,3-bis(cyclohexyl)-l- Transforming activity, 4381 nitroso-, 50 Cell differentiation, 2512 Leukemia L1210 Granulopoietic precursors, 2512 Urea, l-(2-chloroethyI)-3- Levamisole, 4813 Granulopoietic precursors, growth cyclohexyl-1-nitroso-, 50 Purine-6(LH)-thione, 2-amino- in vitro, 2507 DNA 12-O-Tetradecanolyphorbol-13- Proteinases Bacillus subtilis, 4381 acetate Breast neoplasms Transforming activity, 4381 Macrophages, peritoneum, mouse Adenocarcinoma(s), 550 2273 Purines Fibroadenoma, 550 Dimethylamine, N-nitroso- Vinblastine Secretion, in vitro, 550 Cell proliferation, 2695 DNA, 3116 Vincristine Puromycin Proteins Cell proliferation, 2695 Adenosine cyclic 3':5'- Ornithine decarboxylase Vindesine Cell survival, 432 monophosphate Cell proliferation, 2695 Retinoids Cell membrane, 2860 Lysozyme, 914 Prostatic neoplasms Cell transformation, neoplastic Androgen 2860 Putrescine Hormone dependency, rat, 3551 Cell membrane Ornithine decarboxylase Antigens Platelet aggregation, 1217 Rat-1 fibroblasts, 604 Diagnosis, 4658 A31 3T3 cells 12-O-Tetradecanoylphorbol-13- Antigens, neoplasm Cell transformation, neoplastic acetate Diagnostic marker, 2428 2860 Epidermis, mouse, in vitro/in vivo Identification and characteriza BALB/3T3 cells 4013 tion, sera, patients, 2428 Cell transformation, neoplastic Estrogen Pyloric ulcer 2860 Hormone dependency, rat, 3547 Papilloma(s) MCA3T3 cells 3551 W/Wv and SI/SID genotype PC-5-PI cells Cell transformation, neoplastic mice, 3392 2860 Cytogenetics, 524 Hybrid cells Pyrazofurin Phosphoric monoester hydrolase Antibodies, 3850 3924A hepatoma cells Isolation and characterization, rat Neoplasm metastasis Cell cycle, 2869 1245 Pyrazofurin 5'-monophosphate Tamoxifen Platelet aggregation, 1217 Neuroblastoma Active metabolite, 1482 Hormone dependency, rat, 3547 Adenosine cyclic 3':5'- Pyrazofurin S'-monophosphate 3551 Mechanism of action, rat, 2188 monophosphate, 2884 Formyltransferase Receptors, hormone, 2188 Enzyme inhibition, 1482 Proteins, nuclear Imidazole-4-carboxamide-1 -ÃŸ-D- Protease inhibitors see also Histones ribofuranosyl, Hepatoma(s) Hydrazine, 1,2-dimethyl- Purine biosynthesis, rat, 1482 Elastina!, 2539 Carcinogen susceptibility, mouse Pyrazofurin Lung neoplasms 1774 Active metabolite, 1482 MÃ©tastases, 2539 Colonie neoplasms, 1774 Pyrazole, 2,3-dihydro-l //-imida/o(l,2- Protein 45/7.8 6]-,azo- Pseudoisocytidine Hepatoma(s) Biochemical/pharmacological activi Leukemia L1210 cells Isolation and characterization, rat ty Cell cycle, 1103 1623 Phase I clinical study, 4243 Pharmacokinetics, mouse, 1103 Protein kinases P388 cells Pseudomyxoma peritonei Cell transformation, neoplastic Cell cycle, 1103 Adenosine cyclic 3':5'- see Cystadenoma, mucinous Pharmacokinetics, mouse, 1103 monophosphate, 2860 Purine nucleoside phosphorylase /f-Pyrazolo(3,4-d)pyrimidin-4-ol Phosphorylation system, 2860 see Inosine phosphorylase P388 cells

DECEMBER 1980 4917 Subject Index to Volume 40

H-Pyrazolo(3,4-d)pyrimidin-4-ol 1-Pyrophosphate, 5-phosphoribosyl Receptors, /3-adrenergic (cont'd) (cont'd) L1210 cells 12-O-Tetradecanoylphorbol-13- Tumor growth inhibition, mouse Methotrexate, 139 acetate, 240 1885 De novo purine synthesis, 139 Receptors, complement Colonie neoplasms Pyruvate kinase M2 HL-60 cells Tumor growth inhibition, mouse Adenosine cyclic 3':5'- Cell maturity, 1469 1885 monophosphate-independent Uracil, 5-fluoro- Receptors, Fc protein kinase Toxicity reduction, bone marrow Lymphoma(s) Chick embryo cells, 1733 cells, 1885 T-Lymphocytes, 4648 Cell transformation, viral Tumor growth inhibition, mouse Chick embryo cells, 1733 1885 Receptors, glucocorticoid Uridine, deoxy- Guanine, 6-thio- Leukemia(s) Leukocytes, human, 2601 Toxicity reduction, bone marrow Cell cycle cells, 1885 Cytotoxicity, mouse, 1458 Receptors, hormone lH-Pyrazolo(2,3-a)imidazole, 2,3- Leukemia L1210 cells, 1458 Adrenal cortex neoplasms Adenyl cyclase, 3768 di hydro- Quercetin Carcinoma, Ehrlich tumor see Flavone, 3,3',4',5,7- Antiestrogens Ribonucleotide reducÃase, 3891 pentahydroxy- Hormonal control, breast cancer 1750 6/Ã®-Pyrido(4,3-iÂ»)carbazole,5,11- Quinoline, 4-nitro-, 1-oxide Antineoplastic agents dimethyl- Caffeine Breast neoplasms, 2941 Chinese hamster ovary cells Caffeine-sensitive period, lung, Estrogen, 2941 Cytotoxicity, 2390 mouse, 1332 Uterus, rat, in vitro, 2941 Friend leukemia cells Epithelium Benz(a)anthracene, 7,12-dimethyl- Cytotoxicity, 2390 Trachea, rat, 2898 Hormonal control, 1612 L1210 leukemia cells Escherichia coli Mammary neoplasms, 2343 Cytotoxicity, 2390 Mutagenicity vs Cytotoxicity Steroid binding, rat, 1612 Lymphocytes, human 3508 Breast neoplasms Cytotoxicity, 2390 Clinical correlations, male, 991 Radiation, ionizing 17/3-Estradiol, 1750 5ff-Pyrido(4,3-i>)indole, 3-amino-l,4- C3H/10T1/2 mouse embryo cells Estrogen, 3357, 4821 dimethyl- Cell transformation, neoplastic Cytochrome P-450 Estrogen sulfotransferase, 1360 3328 Hormonal manipulation, male Liver microsomes, rat, 2596 Cytotoxicity, 3328 991 5H-Pyrido(4,3-6)indole, 3-amino-l- Nitrosoureas Hormone therapy, 2423 methyl- DNA repair, 771 Megestrol acetate, 2557 Cytochrome P-450 Synergistic effects, 771 Progesterone, 1750, 3357, 4821 Liver microsomes, rat, 2596 Radiation, non-ionizing Prognosis, 3357 Pyrimidine dimers Methotrexate Tamoxifen, 1750 DNA repair DNA synthesis, 1002 Therapeutic response, 2557 Assay techniques, 3181 Leukemia L1210 cells, 1002 Transplantation, heterologous, 95 Uptake enhancement, 1002 Calcitonin Pyrimidine nucleoside phosphorylases BEN cells, 1311 Thymine, l-(2'-deoxy-/3-D- Radiation, shortwave RPMI 3460 Syrian hamster cells glucopyranosyl)- Hyperthermia Glucocorticoids, 2174 Sarcoma(s), 2829 Isolation and characterization Dexamethasone 507 Sarcoma(s) Neoplastic cells/embryonic cells Substrate specificity, 507 Tumor growth, rat, 2829 Uridine, 5-fluoro-2'-deoxy- 2706 Radiotherapy DNA polymerase Isolation and characterization Neoplasm transplantation MCF-7 cells, 1722 507 Antitumor activity, mouse, 26 17/8-Estradiol Substrate specificity, 507 Fibrosarcoma(s), 26 DNA, 1050 Pyrimidine nucleotides Phosphorothioic acid, S-2-(3- Mammary neoplasms, 1050 aminopropylamino)ethyl- Deoxyribonucleoside triphosphates Estrogens Toxicity resistance, 1519 Normal/regenerating/neoplastic/ Breast neoplasms, 3172 neonatal liver, rat, 1286 â€¢y-Rays MCF-7 cells, 3172 Pyrimidine synthesis C3H/10T1/2 mouse embryo cells Dextran-coated charcoal vs su Enzymatic activity Cell transformation, neoplastic crose gradient analyses, 4127 Normal/neoplastic/fetal, human/ 3328 Estrogen sulfotransferase, 1360 rat liver, 1235 Cytotoxicity, 3328 S-phase fractions, human, 1890 Hereditary diseases Pyrimidines, 5-fluoro- Glucocorticoids Radiosensitivity, human cells S-49 lymphoma cells Clonal proliferation, 563 926 Toxicity vs cell cycle, 4209 HL-60 cells, 563 RNA/DNA Receptors, /3-adrenergic KG-1 cells, 563 Toxicity vs cell cycle, 4209 Butyric acid Leukemia, myeloblastic, 563

4918 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Receptors, hormone (cont'd) Retinoic acid (cont'd) Retinoids (cont'd) B-Lymphocytes, 2240 Normal/neoplastic tissue, human Normal/neoplastic cells, human Lymphocytosis, bovine, 2240 Binding, in vitro, 4221 4817 Virus, bovine leukemia, 2240 Plasminogen activator Structure-activity relationship Hormonal therapy Normal/neoplastic cells, human Trachea, hamster, 3413 S-phase fractions, human, 1890 4817 Urea, N-methyl-JV-nitroso- Mammary neoplasms 12-O-Tetradecanoylphorbol-13- Carcinogenicity, rat, 3095 Estradiol, 1la-methoxyethinyl- acetate Retino! 3232 Inhibition of tumor promotion, Normal/neoplastic tissue, human Estrogen, 235, 3232 mouse, 2367 Binding, in vitro, 4221 Ovariectomy, 3232 Ornithine decarboxylase, 2367 Pregnant mouse, 3361 Retinoic acid-binding protein Retinyl acetate Prolactin, 1674 Benz(a)anthracene, 7,12-dimethyl- Melanoma(s) Tamoxifen, 3232 Mammary neoplasms, 1140 Retinoids, 1097 Urea, JV-methyl-W-nitroso- DNA synthesis Retinoids 4628 Benz(a)anthracene, 7,12-dimethyl- Melanoma S91 cells, 1097 Molybdate ion 1109 Prostate gland, human, 2234 Retinoic acid, 13-c/s- Rat, female Sprague-Dawley Nafoxidine Ornithine decarboxylase 1109 Estradiol, 3821 Thiazole, 2-amino-4-(5-nitro-2- Urea, JV-methyl-N-nitroso-, 1109 Uterus, guinea pig, 3821 furyl)-, 1897 Mammary neoplasms Progestagen Tumorigenesis inhibition, 1140 Retinoic acid, 5,6-dihydro- Urea, /V-methyl-A'-nitroso- Hormonal control, breast cancer 12-O-Tetradecanoylphorbol-13- 1750 Carcinogenicity, rat, 3095 acetate Progesterone Dextran-coated charcoal vs su Inhibition of tumor promotion, Retinyl palmitate mouse, 2367 Corynebacterium parvum crose gradient analyses, 4127 Ornithine decarboxylase, 2367 Antitumor activity, mouse, 4617 Estrogen sulfotransferase, 1360 Lung neoplasms, 4617 Prostate gland, human, 2234 Retinoic acid, 5,6-epoxy- Prolactin 12-O-Tetradecanoylphorbol-13- Review Broparestrol, 1674 acetate Antineoplastic agents Prostatic neoplasms Inhibition of tumor promotion, Breast neoplasms, 4335 Tamoxifen, 2188 mouse, 2367 Therapeutic index, 4335 Sarcoma(s) Ornithine decarboxylase, 2367 Carcinogens Sex factors, human, 861 Human, 1 Retinoids Tamoxifen Drug therapy Binding affinity assay Estradiol, 3821 Breast neoplasms 4335 Growth inhibition, 212 Uterus, guinea pig, 3821 Retinoic acid-binding protein, Therapeutic index, 4335 Thymoma(s) Esophageal neoplasms testes/mammary tumors, rat Corticosensitivity, in vitro, 2020 Epidemiology, China, 2633 212 Glucocorticoids, 2020 Leukemia(s) Urea, N-methyl-N-nitroso- Cell adhesion C3H/10T1/2CL8 mouse fibrob- Oncogenic viruses, 3405 Estrogen, 235 Lymphoma(s) last cells, 3141 Oncogenic viruses, 3405 Rectal neoplasms Cell transformation Therapy Doxorubicin 3T12 fibroblast cells, 1944 Breast neoplasms, 3863 Derivatives, 4682 Cellular adhesion, 1944 Cell transformation, neoplastic Ribonucleotide, 5-amino-4-imidazole Resiniferatoxin 12-O-Tetradecanoylphorbol-13- C3H/10T1/2CL8 mouse fibrob carboxylic acid last cells, 3141 L-Alanosine acetate MIRW human melanoma cells Inflammation, 1400 Adduci formation, 4390 Target sites, chicken/mouse fi- Cell differentiation, 2194 Adenylosuccinate synthetase Tyrosinase, 2194 4390 broblasts, 1400 Lysozyme 5'-Ribonucleotide phosphohydrolase Retinole acid Myeloid leukemia cells, 914 Lymphocytes, null-type Breast neoplasms Puromycin, 914 Deoxynucleosides, 3383 Binding protein, 4265 Melanoma(s) Normal/dysplastic/neoplastic tis Growth inhibition, in vitro, 1097 Ribonucleotide reductase sue, human, 4265 Retinoic acid-binding protein Adenine, 9-/3-D-arabinofuranosyl, 5'- 3T3 ceils 1097 triphosphate Cell transformation, viral, 3089 Melanoma S91 cells Molt-4F lymphoblast cells, 3555 Plasminogen activator, 3089 Growth inhibition, in vitro, 1097 Carcinoma, Ehrlich tumor Mammary neoplasms Retinoic acid-binding protein l//-Pyrazolo(2,3-a)imidazole, 2,3- Benz(a)anthracene, 7,12-dimethyl- 1097 dihydro-, 3891 47 Phorbol myristate acetate Cytosine, 9-ÃŸ-D-arabinofuranosyl, 5'-triphosphate Binding proteins, 47 Hs939 melanoma cells, 3345 Competitive inhibition, 47 Melanogenesis, 3345 Molt-4F lymphoblast cells, 3555 Urea, JV-methyl-N-nitroso-, 47 Plasminogen activator Deoxyadenosine triphosphate

DECEMBER 1980 4919 Subject Index to Volume 40

Ribonucleotide reducÃase(cont'd) RNase (cont'd) Sarcoma, osteogenic Molt-4F lymphoblast cells, 3555 Cytotoxicity, tumor cells, 3740 Methotrexate Thymidine Serratia marcescens Solid tumor penetration, 3665 CCRF-CM cells, 1718 SaD2 fibrosarcoma cells, 1501 Uridine, 5-iodo-2'-deoxy, 5'- Procollagen Bone neoplasms, 325 Rubidium triphosphate Transformation, viral Anthracylic antibiotics Molt-4F lymphoblast cells, 3555 Virus, type A, 127 Cardiotoxicity, mechanism, 4581 Ricin C3H/10T1/2 CL8 mouse fibrob- Virus, type C, 127 Virus, oncorna Adriamycin last cells, 4581 L1210 leukemia cells, 3735 Virus, type A, 127 Cytotoxicity/synergistic drug ac Hunting syndrome Virus, type C, 127 Lymphoma(s) tion, 3735 Sarcoma(s) Virus, Friend, 448 Antigens, fetal RNA Virus, Gross, 448 Acetamide, thio- Complement-dependent cytotoxic Liver nuclei, rat, 75 T51B rat liver cells reactivity, sera, human, 979 Cross-protection, mouse/hamster Nucleoside triphosphatase, 75 Calcium, 4541 Cell-mediated cytotoxicity, spleno- DNA synthesis, 4541 1568 Lung neoplasms Antigens, neoplasm cytes, mouse Cross-protection, mouse/hamster Letter to the editor, 1762, 1763 Tumor promotion, mouse, 4322 Poly A Urethan 1568 Aged/neonatal/neoplastic/ Tumor promotion, mouse, 4322 Isolation and characterization 4204 regenerating liver, rat, 1449 Saccharomyces cerevisiae Half-life of decay, rat liver, 1449 Cathepsin D Anthralin Caloric restriction, mouse, 1680 RNA, messenger Mitotic recombination/ Cell culture Benz(a)anthracene, 7,12-dimethyl- mutagenicity, 2323 Mechanical/enzymatic disaggrega- Mammary neoplasms, 362 Catechol tion, 2160 Casein Mitotic recombination/ Morphological study, 2160 Hormonal influences, mouse, 362 mutagenicity, 2323 Soft agar growth medium, 2160 a-Fetoprotein lodoacetate Diet Normal/hyperplastic/neoplastic Mitotic recombination/ Body composition vs tumor liver, rat, 3713 mutagenicity, 2323 growth, adult mouse, 2516 12-O-Tetradecanoylphorbol-13- Neoplasm transplantation Gluconeogenesis Mammary neoplasms, 362 acetate Tumor glucose demand, rat RNA, polysomal polyadenylated Mitotic recombination/ 1699 Normal/hyperplastic/neoplastic mutagenicity, 2323 /3-Glucuronidase liver, rat, 3713 Salmonella typhimurimn Caloric restriction, mouse, 1680 RNA, polysomal polyadenylated Benzo(c)phenanthrene Hyperglycemia RNA, messenger Mutagenicity, 2876 Hyperthermia, 4728 Normal/hyperplastic/neoplastic Benzo(j)fluoranthene Hyperthermia liver, rat, 3713 Benzo(k)fluoranthene, 4528 Tumor growth, rat, 2829 Cell transformation, viral B-Lymphocytes RNA synthesis NL2/NL3/NL4 lymphoblastoid Macrophage activation, mouse, in Urea, 1-(2-chloroethyl)-3-cycIohexyl- vitro, 2054 1-nitroso- cells, 4775 Cyclopenta(cd)pyrene T-Lymphocytes Ependymoma, 939 Mutagenic metabolites, 3940 Macrophage activation, mouse, in RNA, transfer, methyltransferases Hydroxamic acids vitro, 2054 5-Azacytidine DNA carbamoylation vs Picolinic acid, 3-mercapto- Cytosine-5-methyltransferase mutagenicity, 4704 Gluconeogenesis, 1699 2701 Niridazole Radiation, shortwave Estrogen Mutagenicity, 4599 Tumor growth, rat, 2829 Sex factors, liver, rat, 620 Receptors, hormone Sarcoma, Crocker 180 Mammary neoplasms Sex factors, human, 861 Neoplasm mÃ©tastases Adenocarcinoma(s), 417 Tumorilysin Guanosine, JV-methyl-, 417 Lysosomal enzymes, 3281 Characterization, 1255 Tumor enzyme activity, mouse Testosterone 3281 Scientific conferences Sex factors, liver, rat, 620 National Cancer Institute, 2617 Sarcoma, Ewing's RNA, viral Secretin Cell transformation, viral Procollagen Bone neoplasms, Colonie neoplasms Cell cycle, 3177 325 Adenosine cyclic 3':5'- Virus, adeno 2, 3177 Sarcoma, hemangioendotbelial monophosphate, 2529 Virus, polyoma, 3177 see Angiosarcoma Virus, SV40, 3177 Selenium Sarcoma, mast cell Acetamide, N-fluoren-2-yl- RNase Lymphocytes Binding, liver, rat, 2670 Seminal plasma, bovine Zonal rotor centrifugation, 1791 DNA repair, 2670

4920 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Selenium (cont'd) Sister chromatid exchanges (cont'd) Skin neoplasms (cont'd) DNA, single strand, 2670 Cell transformation, viral Tumorigenicity, newborn mouse DNA synthesis NL2/NL3/NL4 lymphoblastoid 203 DNA polymerase, 2455 cells, 4775 NHIK 3025 carcinoma cells Smoking Serine, diazoacetate (ester) Hematoporphyrin, 2915 Epoxide hydrolase Pancreatic neoplasms X-rays, 2915 Lymphocytes, fresh/mitogen- Carcinoma(s), 592 Leukemia, acute nonlymphocytic stimulated, 2552 Serrada marcescens Growth kinetics, human marrow Sodium Polyribosomes cells, 1292 Ion concentration Tumor suppression, mouse, 1501 Lymphoma(s) Cell transformation, neoplastic Pronase Drug therapy, 4786 1493 SaD2 fibrosarcoma cells, 1501 X-rays, 4786 Mitogenesis, 1493 RNAse Mitomycin C OncÃ´genesis,1493 SaD2 fibrosarcoma cells, 1501 Lymphocytes, 477 Sodium n-butyrate Sezary syndrome see Butyric acid, sodium salt Chromosome aberrations, 3426 /3-Sitosterol Mitogen-stimulated lymphocytes Sodium cyanate Colonie neoplasms Case report, 3426 see Cyanic acid, sodium salt Anticarcinogenic activity, rat Sialic acid 403 Sodium saccharin BHK cells Diet, vegetarian, 403 Bladder neoplasms Cell transformation, viral, 1550 Urea, N-methyl-N-nitroso-, 403 Promoting agent, 734 Cytosine, l-ÃŸ-D-arabinofuranosyl-, Ultrastructural study, rat, 734 5'-triphosphate DNA synthesis WI-38 cells, 1940 Skin neoplasms Promoting agent, 734 Cytosine, 1-/3-D-arabinofuranosyl-, Benzo(c)phenanthrene 5'-monophosphate Bay-region diol epoxides, 3910 Soft agar WI-38 cells, 1940 Tumorigenicity, mouse, 3910 Solid tumor cells Glycoproteins Benzo(e)pyrene Cell culture, 4151 BHK cells, 1550 Dihydrodiols/diol-epoxides, 1981 Somatomedin Radioactive labeling, 1550 Tumorigenicity, newborn mouse Mammary neoplasms 203 Sialoglycoproteins Isolation and characterization Benzo(e)pyrene, t/ans-4,5-dihydroxy- 4368 Adenocarcinoma(s) 4,5-dihydro- Peanut agglutinin, 1873 Organ culture, mouse, 4368 T-Antigen Tumorigenicity, newborn mouse Polypeptides, 4368 203 Peanut agglutinin, 1873 Benzo(e)pyrene, frans-9,10- Somatostatin Cytosine, 1-/3-D-arabinofuranosyl-, 5'-monophosphate dihydroxy-9,10-dihydro- Thyroid neoplasms WI-38 cells, 1940 Tumorigenicity, newborn mouse Secretion, rat, 4059 203 Sialyltransferases, 1940 Benzo(e)pyrene, t/ans-9,10- Sorbitan monooleate, polyoxyethylene Cytosine, 1-/3-D-arabinofuranosyl-, dihydroxy-9,10,11,12- derivative 5'-triphosphate Bacillus Calmette-Guerin tetrahydro- WI-38 cells, 1940 Antitumor activity, 975 Tumorigenicity, newborn mouse Sialyltransferases, 1940 Emulsified components, 975 203 Trehalose-6,6'-dimycolate Chrysene Sialyltransferases Dihydrodiols/diol-epoxides, 1981 Antitumor activity, 975 Carcinoembryonic antigen Dibenz(a,c)anthracene Emulsified components, 975 Gastrointestinal neoplasms, 1300 Dihydrodiols/diol-epoxides, 1981 Cytosine, 1-/3-D-arabinofuranosyl-5'- Spermidine Dibenz(a,h)anthracene Guanidine, 1,-1'-(methylethanedi- monophosphate Dihydrodiols/diol-epoxides, 1981 ylidenedinhrilo)di- WI-38 cells, 1940 Dibenzo-p-dioxin, 2,3,7,8- Fibroblasts, 3T3, 293 Sialoglycoproteins, 1940 tetrachloro- Cytosine, l-ÃŸ-D-arabinofuranosyl-5'- Carcinogens, chemical, 1580 Spermine triphosphate Indomethacin Guanidine, 1,-1'-(methylethanedi- WI-38 cells, 1940 Ornithine decarboxylase, 308 ylidenedinitrilo)di- Sialoglycoproteins, 1940 7-Methylbenz(a)anthracene Gastrointestinal neoplasms Dihydrodiols/diol-epoxides, 1981 Fibroblasts, 3T3, 293 Tumor burden, diagnosis, 1300 Papilloma(s) Ornithine decarboxylase, 308 Squamous cell carcinoma Prostaglandins, 308 see Epidermoid carcinoma(s) Sister chromatid exchanges SerratÂ¡amarcescens Benzene Polyribosomes, 1501 Standardized nomenclature Cell cycle kinetics, lymphocytes, 12-O-Tetradecanoylphorbol-13- Mouse, inbred strains human, 1189 acetate Origins, characteristics, strain dis Cytotoxic metabolites, 1189 Ornithine decarboxylase, 308 tribution of alÃeles,2083

DECEMBER 1980 4921 Subject Index to Volume 40

Starvation Superoxide radical Testis Gluconeogenesis, 1699 Hepatoma, Morris Alkaline phosphatase Sterigmatocystin Mitochondria, normal/neoplastic D-Variant enzyme, placental-type Hepatocarcinogenesis, rat liver, rat, 3686 1506 DNA-adduct formation, 4085 Suppressor cells Developmental gene expression 1506 /raii.v-Stilbene oxide Antigens, neoplasm Immune response, rat, 2129 Aryl hydrocarbon hydroxylase Epoxide hydrolase Bacillus Calmette-Guerin Hormone regulation, 2486 Lymphocytes, fresh/mitogen- Bone marrow/spleen, mouse, 80 Cytochrome P-450 stimulated, 2552 Macrophage-granulocyte colony- Hormone regulation, 2486 4,4'-Stilbenediol, a,a'-diethyl- forming cells, 80 Epoxide hydrase Benz(a)anthracene, 7,12-dimethyl- Cyclophosphamide Hormone regulation, 2486 Glutathione transferase Mammary neoplasms, 1808 Fibrosarcoma(s), 2756 Hormone regulation, 2486 Synergistic effect, rat, 1808 Immune response, mouse, 2756 Cervix neoplasms Leukemia L1210 Vaccines, 3832 Ultrastructural/morphometric Testosterone Lymphoma(s) study, 1558 Adenosylmethionine decarboxylase Serum/tumor tissue, human Sex factors, liver, rat, 620 Stomach neoplasms 4648 Aryl hydrocarbon hydroxylase Adenocarcinoma(s) Mammary neoplasms Antigens, neoplasm, 897 IgG, 3477 Testis, hypophysectomized rat 2486 Glycolipids, 897 Immunization, rat, 3477 Epoxide hydrase Benzo(a)pyrene Lymphocyte cytotoxicity, in vitro Testis, hypophysectomized rat Phenol, (1,1-dimethyl)-4-methoxy- 3477 Thymic hormones 2486 2820 Glutathione transferase Phenolic compounds, 2820 Blood levels, cancer patients Testis, hypophysectomized rat Phenolic compounds 3134 X-rays 2486 Anticarcinogenic activity, mouse tRNA, methyltransferases Blood levels, cancer patients 2820 Sex factors, liver, rat, 620 Pyloric ulcer 3134 Uracil, 5-fluoro- W/Wv and SI/SID genotype Surface-active agents Antitoxic activity, mouse, 2730 mice, 3392 Mouse/hamster, neoplastic/ Mammary neoplasms, 2730 Sialyltransferase nonneoplastic cells Tumor burden, diagnosis, 1300 Growth inhibition, in vivo vs in Sulfoglycoprotein, fetal vitro, 1173 2,3,7,8-Tetrachlorodibenzo-p-dioxin Diagnostic screening, 4308 see Dibenzo-p-dioxin, 2,3,7,8- Gastric juice, 4308 Talisomycin DNA, single-strand tetrachloro- Streptococcus mutons Bacteriophage PM-2, 4173 Line 10 hepatocarcinoma cells Tumor growth, guinea pig, 3211 Tamoxifen 12-O-Tetradecanoylphorbol-13-acetate Breast neoplasms Adenosine cyclic 3':5'- Hepatoma(s) Tumor growth, guinea pig, 3211 Receptors, hormone, 1750 monophosphate Mammary neoplasms Epidermal cells, mouse, 2653 Sulfoglycoprotein, fetal Receptors, hormone, 3232 Benz(a)anthracene, 7,12-dimethyl- Stomach neoplasms Urea, ./V-methyl-JV-nitroso-,235 Carcinogenesis, trachea, rat, 4352 Diagnostic screening, 4308 Prostatic neoplasms Two-stage carcinogenesis, hamster Gastric juice, 4308 Hormone dependency, rat, 3547 155 3551 Sulfonic acid, p-chloromercuriphenyl- Butyric acid Mechanism of action, rat, 2188 Receptors, /3-adrenergic, 240 Methotrexate Receptors, hormone, 2188 Skin, mouse, 240 Transport/binding/ Receptors, hormone Carcinogenicity, skin, mouse polyglutamation, rat hepato- Estradiol, 3821 cytes, 573 Inflammatory response, mouse Uterus, guinea pig, 3821 2273 Sulfotransferase Testicular neoplasms Cell differentiation Benzidine, JV-hydroxy-Ar,JV-diacetyl- Carcinoma(s) Friend erythroleukemia cells Carcinogenic metabolite, rodents Transplantation, heterologous 3780 751 949 Neural crest cells, 2465 Hydroxylamines, JV-acyl-JV-2- In vivo vs in vitro growth charac Melanocytes, chick embryo, 2465 fluorenyl- teristics, 949 Cell nucleus Ames test, 1204 Cytogenetics Site of action, 1066 Enzyme activity, liver, rat, 1204 Chromosomes, marker, 796 Swiss 3T3 mouse cells, 1066 Germ cell tumor Cell transformaiton, neoplastic Superoxide dismutase Morphological/ultrastructural/ Hepatoma, Morris C3H 10T1/2 cells, 1915 antigenic characteristics, 2500 3BM-78 cells Mitochondria, normal/neoplastic Leydig cells liver, rat, 3686 Specific esterase inhibition, mouse Carcinogenic effect, mouse, 1006 866

4922 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

12-O-Tetradecanoylphorbol-13-acetate 12-O-Tetradecanoylphorbol-13-acetate 2,6,10,14-Tetramethylpentadecane (cont'd) (cont'd) see also Pentadecane, 2,6,10,14- CHO cells Binding, brain tissue, mouse tetramethyl Chromosome aberrations, 3245 3635 C3H/10T1/2 mouse embryo fibrob- Phorbol-12-13-didecanoate Theophylline last cells Hep G; human hepatoma cells HeLa-S3 cells Cytidine, 5-aza, 334 4433 Neocarzinostatin, 3786 Morphological changes, 4709 Epidermal cells, human/guinea L1210 cells HL-60 cells pig, 4433 Urea, l,3-bis(2-chloroethyl)-l- Cell maturity, 1469 Fibroblasts, hamster/rat/chick/ nitroso-, 2202 Granulocytes, 1469 mouse/human, 4433 Syrian hamster embryo cells Lipids, 3674 Phospholipids Cell transformation, neoplastic NADPH oxidase, 1469 Lymphocytes, bovine, 776 2411 Oxygen-dependent synthesis, 776 V79 cells Thymidine incorporation, 2411 Chromosome aberrations, 3245 Plasminogen Leukemia(s) Chrysene, 5-methyl- Macrophages, peritoneum, mouse Mortality, mouse, 2202 Carcinogenic activity, mouse skin 2273 Urea, l,3-bis(2-chloroethyl)-l- nitroso-, 2202 1396 Plasminogen activators Dihydrodiols, 1396 HeLa cells, 849 DNA synthesis Prostaglandin biosynthesis, 849 Thermotolerance Lectin-stimulated lymphocytes, HA-1 Chinese hamster ovary fibrob- Prostaglandins E bovine, 3307 Macrophages, peritoneum, mouse last cells 5,8,11,14-Eicosatetraynoic acid Effect of cell medium, 4501 2273 Oxygen-dependent synthesis, 776 Hyperthermia Putrescine Critical temperature, 4485 Erythroleukemia Epidermis, mouse, in vitro/in vivo Cell differentiation, 3369 Mathematical analysis, cell killing 4013 Plasminogen activator, 3369 4485 Virus genonme expression, 3369 Resiniferatoxin Inflammation, 1400 Ether, bis(chloromethyl) Target sites, chicken/mouse fi- Thiazole, 2-amino-4-(5-nitro-2-furyD- Carcinogenicity, mouse, 352 S-Adenosyl-L-methionine decarboxy Ethylene, chloro- oxide broblasts, 1400 Retinoic acid lase Carcinogenicity, mouse, 352 Guanosine cyclic 3':5'- Inhibition of tumor promotion, Enzyme activity, mouse, 1897 mouse, 2367 Bladder neoplasms monophosphate Ornithine decarboxylase, 2367 Epithelium, 1897 Epidermal cells, mouse, 2653 Retinoic acid, 5,6-dihydro- Ornithine decarboxylase Hepatoma AH-130 Inhibition of tumor promotion, Enzyme activity, mouse, 1897 Ascitic fluid, 472 Retinoic acid, 13-c/s-, 1897 Hypoxanthine-guanine phos- mouse, 2367 Ornithine decarboxylase, 2367 Thioacetamide phoribosyltransferase Retinoic acid, 5,6-epoxy- see also Acetamide, thio- Intercellular communication, epi Inhibition of tumor promotion, dermal cells/fibroblasts, mouse Hepatocytes, rat mouse, 2367 Collagen gel-nylon mesh culture 2935 Ornithine decarboxylase, 2367 3259 Indomethacin Retinoids Oxygen-dependent synthesis, 776 Hs939 melanoma cells, 3345 6-Thioguanine Insulin Melanogenesis, 3345 see Purine-6(l/i)-thione, 2-amino- Glucose, 3827 Saccharomyces cerevisiae Thiotepa Pancreatic islets, rat, 3827 Mitotic recombination/ Lymphocytes Hyperthermia mutagenicity, 2323 Cystadenoma, mucinous, 256 Binding assay, 1119 Skin neoplasms Mitogenic response, 1119 Tumorigenicity, newborn mouse Third Annual Interdisciplinary Cancer Melanoma(s) Research Workshop, 2943 Benz(a)anthracene, 7,12-dimethyl- 203 Ultraviolet rays 155 Thrombocytopenia Mitotic recombination/ Leukemia L1210 Mm-1 cells mutagenicity, 2323 Growth enhancement, 472 Megokaryocytopoiesis, mouse Mutations, 3245 667 Ornithine decarboxylase X-rays Enzyme induction, mouse skin Carcinogenicity enhancement Thymic hormones 308 1915 Suppressor cells Epidermal cells, mouse, 2653 Blood levels, cancer patients 3134 Epidermis, mouse, in vitro/in vivo Tetrahydrouridine 4013 see Undine, tetrahydro- Thymidine Skin neoplasms, 308 Antineoplastic agents Phagocytosis Pharmacokinetics, clinical study, Macrophages, mouse, 1028 Tetramethoxypropane phase 1-2, 818 P388D, cells, 1028 Propanediol Uracil, 5-fluoro-, 107 Phorbol 12,13-dibutyrate Mutagenic metabolites, 276 Antitumor activity, mouse

DECEMBER 1980 4923 Subject Index to Volume 40

Thymidine (cont'd) Thymoma(s) (cont'd) TrachÃ©alneoplasms (cont'd) Letter to the editor, 1764 Glucocorticoids, 2020 Carcinogenesis, rat, 2898 CCRF-CM cells X-rays Cytidine, 5'-triphosphate, deoxy- Epithelium Immunodepression, 357 1718 Cell transformation, neoplastic Growth inhibition, 1718 4403 Guanosine, 5'-triphosphate, Thyroid gland Morphological/biochemical cha deoxy-, 1718 Benz(a)anthracene, 7,12-dimethyl- racteristics, trachea, hamster Mammary neoplasms, 2336 Ribonucleotide reducÃase,1718 4403 12-O-Tetradecanoyl phorbol-13- Colonie neoplasms Antitumor activity, rat, 1274 Thyroid neoplasms acetate Cytidine, deoxy-, 1274 Carcinoma(s) Carcinogenesis, trachea, rat, 4352 Cytosine, 1-/3-D-arabinofuranosyl- Calcitonin, 1419 Urea, Ar-methyl-JV-nitroso- 1274 Immunohistological/light and Cannula system, 609 Cytosine, 1-/3-D-arabinofuranosyl- electron microscopy, rat, 1419 Morphogenesis, Syrian golden S'-triphosphate, 1274 Secretory granules, 1419 hamster, 609 Toxicity, rat, 1274 Somatostatin Transaminase Cytidine, deoxy- Secretion, rat, 4059 Adriamycin, 1263 Intracellular incorporation, 1525 Thyronine, 3,3',5-triiodo- Adriamycinol, 1263 Cytosine, 1-/J-D-arabinofuranosyl- Hepatoma(s) L1210 leukemia cells, 1525 Transformation, neoplastic Hepatocyte proliferation, rat Syrian hamster embryo cells Cytotoxicity enhancement, 1525 2417 Intracellular incorporation, 1525 Aneuploidy, 91 DNA synthesis dTMP-synthetase Multistage model, 91 Uracil, 5-fluoro- Antitumor activity, 818 Transformation, viral Methotrexate Carcinoma cells, human, 4113 Fibroblasts, 3T3 Drug rescue, 1824 Fibroblastic cells, human, mouse Virus, SV40, 293 Immunosuppression, 650 4113 Sarcoma, osteogenic Furine synthesis, 1824 Inhibition of antitumor activity, Virus, type A, 127 Transplantation, heterologous in vitro, 4113 Virus, type C, 127 Letter to the editor, 1764 Tobacco Uracil, 5-fluoro- 1-Butanone, 4-(A^-nitrosoamino)-1-(3- Transplantation, heterologous SK-L7 cells, 1543 pyridyl)- Breast neoplasms Growth kinetics, 1543 Nude mouse, 95 Tumorigenicity, rat, 4144 Uridine, 5-fluoro-2'-deoxy-, 1543 Receptors, hormone, 95 o-Tocopherol Vascularization, 95 Thymidine kinase Adriamycin Lymphoid cells Hydrocortisone Tumor-bearing vs normal, neona Cardiac toxicity, rabbit, 1022 Splenectomy and/or irradiated 2033 tal/adult rat, 744 nude mouse, 2588 Nucleic acid synthesis Glutathione, 1022 Pancreatic neoplasms Hydrazine, 1,1-dimethyl- Lung neoplasms, 2295 Amylase activity, nude mouse/ Carcinogenicity, mouse, 1329 cultured cells, 592 Thymidylate synthetase Colonie neoplasms, 1329 Pleural neoplasms Hydrocortisone p-Toluamide, JV-isopropyl-a-(2- Mesothelioma, 181 Tumor-bearing vs normal, neona Testicular neoplasms tal/adult rat, 744 methylazo)- Barbituric acid, 5-ethyl-5-phenyl- Carcinoma(s), 949 Uracil, 5-fluoro- Thymidine L1210 cells, 322 Liver microsomes, rat/rabbit Uridine, 5'-monophosphate, 5- 3524 Letter to the editor, 1764 Urea, 3-[(4-amino-2-methyl-5- fluoro-2'-deoxy-, 1431 Metabolites, 3524 Flavone, 5,6-benzo- pyrimidinyl)methyl] Thymine, l-(2'-deoxy-/3-D- Liver microsomes, rat/rabbit Antineoplastic agents, 133 glucopyranosyl)- 3524 Transplantation, homologous Pyrimidine nucleoside phosphory- Metabolites, 3524 Lymphoid cells lases Splenectomy and/or irradiated Isolation and characterization Toxoplasma gondii Nervous system neoplasms nude mouse, 2588 507 Decane, 2,6,10,14-tetramethylpenta- Substrate specificity, 507 Inflammatory response, rat/ mouse, 1240 Plasmacytoma, 579 Thymocytes Tumor inhibition, rat/mouse Transplantation, neoplasm Monosialoganglioside 1240 SCI 15 mouse mammary carcinoma Binding, normal/neoplastic Urea, 1-ethy1-1-nitroso-, 1240 cells thymocytes, mouse, 2808 TrachÃ©alneoplasms Serial passage, mouse, 4781 Thymoina(s) Carcinoma, epidermoid Trehalose-6,6'-dimycolate Immunosuppression Cell cycle vs tumorigenicity Sorbitan monooleate, polyoxyethy- RFM mouse, 3403 4467 lene derivative Receptors, hormonal Cell subpopulations, rat, 4467 Antitumor activity, 975 Corticosensitivity, in vitro, 2020 DNA repair Emulsified components, 975

4924 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Triphenylene Ultraviolet rays (cont'd) Uracil, 5-fluoro- (cont'd) Diol-epoxides/tetrahydroepoxides Methanesulfonic acid, methyl es Cell culture, 2743 Mutagenesis, 1985 ter, 582 Oxypurinol Trypsin Postreplication repair, mouse Toxicity reduction, bone marrow Mammary neoplasms 1867 cells, 1885 Cell transformation, neoplastia Skin, human, 3181 Pharmacokinetics X-rays, 582 2383 Oral, rapid/slow iv infusion Xeroderma pigmentosum, 2736 2223 Tryptophan Fibrosarcoma(s) Phase I/pharmacological studies Cytochrome P-450 Neoplasm transplantation, 625 Intraperitoneal administration Liver microsomes, rat, 2596 lodoacetate 567 Tumor spheroids Mitotic recombination/ Plasmacytoma EMTo/Ro mouse mammary tumor mutagenicity, 2323 Immune response, mouse, 2790 cells Neoplasm mÃ©tastases H-Pyrazolo(3,4-d)pyrimidin-4-ol Cell characteristics, 3956 Fibrosarcoma(s), 625 Toxicity reduction, bone marrow WAZ-2T( + SA) adenocarcinoma 12-O-Tetradecanoylphorbol-13- cells, 1885 cells acetate Tumor growth inhibition, mouse Spheroid attachment, 4631 Mitotic recombination/ 1885 Endothelium mutagenicity, 2323 Testosterone Spheroid attachment, 4631 Mutations, 3245 Antitoxic activity, mouse, 2730 Xeroderma pigmentosum Mammary neoplasms, 2730 Tumorilysin Virus, adeno type 2, 3945 Thymidine Foreign body tumorigenesis SK-L7 cells, 1543 Characterization, 1255 Uracil-DNA glycosylase Growth kinetics, 1543 Diffusion chambers, 1255 Uracil, 5-fluoro- Uridine, 5-fluoro-2'-deoxy-, 1543 DNA, 998 Uracil-DNA glycosylase Tween 80 Lymphocytes, human, 998 see Sorbitan monooleate, polyoxy- DNA, 998 ethylene derivative Uracil, 5-fluoro- Lymphocytes, human, 998 Antineoplastic agents Uracil, R ,S-1 -(tetrahydro-2-furanyl)- Pharmacokinetics, 107 Antineoplastic agents, 2814 Tyrosinase Thymidine, 107 Uridine, 5-fluoro- 2'-deoxy-, Alanine, 3-(3,4-dihydroxyphenyl)-, L- S'-monophosphate, HT29 cells DNA polymerase, 1414 Drug resistance, 1574 Thymidylate synthetase, 1431 Butyrophenone, 4-[4-(p- Isolation and characterization, chlorophenyl)-4- Uracil, 5-fluoro-l-(tetrahydro-2- hydroxypiperidino]-4'-fluoro- subpopulation, 1574 furanyl)- P388 leukemia cells DNA polymerase, 1414 Allogeneic lymphoid cell transfer Sensitive vs resistant cells, 1431 MIRW human melanoma cells Antitumor activity, rat, 954 Transport and metabolism, 1431 Retinoids, 2194 Antineoplastic agents 9L brain tumor cells â€¢v-Butyrolactone, 2814 Ultraviolet rays Dose-response culture, 3202 Metabolites, in vivo/in vitro Anthralin Coenzyme Q,0 2814 Mitotic recombination/ Membrane potential difference, Uracil, 5-fluoro-, 2814 mutagenicity, 2323 liver, rat, 1663 Fibrosarcoma(s) Benzo(a)pyrene Potassium, 1663 Antitumor activity, rat, 954 Benzo(a)pyrene-DNA adducts Colonie neoplasms Immunotherapy 245 HT29 cells, 1574 Hypersensitivity, delayed, 954 DNA, 245 Gastrointestinal absorption, hu Single-strand breaks, 245 man, 3400 Urea, 3-[(4-amino-2-methyl-5- Catechol Deoxyuridine triphosphate diphos- pyrimidinyDmethyl] l-(2- Mitotic recombination/ phorylase chloroethy I)-nitroso - mutagenicity, 2323 DNA, 998 Antineoplastic agents Cell transformation Lymphocytes, human, 998 Transplantation, heterologous Anchorage-independent growth, dTMP-synthetase 133 human embryo cells, 1934 Carcinoma cells, human, 4113 Ultrastructural study, nucleolus, Photoreactivation, 1934 Fibroblastic cells, human, mouse mouse, 133 Pyrimidine dimers, 1934 4113 Cell transformation, neoplastic Inhibition of antitumor activity, Urea, l,3-bis(2-chloroethyl)-l-nitroso- Methanesulfonic acid, methyl es in vitro, 4113 L1210 leukemia cells ter, 582 Glycoprotein Cytotoxicity, 3723 Virus, herpes simplex type 2 Metabolite pools, 322 Theophylline, 2202 2213 L1210 cells X-rays, 582 MOPC 104E myeloma cells Glycoprotein, 322 IgM, 2372 DNA repair Thymidylate synthetase, 322 Plateau phase, mouse, 2372 Age, sex, diet factors, rat, 3719 Leukemia P388 9L brain tumor cells Ataxia telangiectasia, 984 Lipophilic derivative, 4758 DNA damage, 3186 Fibroblast cell cultures, controls/ MÃ©tastases, 4758 Leukemia(s) patients, 2736 Ovarian neoplasms Theophylline, 2202

DECEMBER 1980 4925 Subject Index to Volume 40

Urea, l,3-bis(cyclohexyl)-l-nitroso- Urea, JV-ethyl-JV-nitroso- (cont'd) Uridine, deoxy- (cont'd) L1210 cells Transplacental carcinogenesis, rat Toxicity reduction, bone marrow DNA repair, 50 3973 cells, 1885 Proteinase K, 50 Uridine diphosphogalactose 4'- Urea hydrochloride, l-(4-amino-2- Urea, (chloro-2-ethyl)-l-ribofuranosyl-3- methyl-5-pyriimdinyl)methyl-3-<2- epimerase nitroso- chloroethyh-3-nitroso- Hepatoma, Morris Antineoplastic agents Meningeal carcinomatasis Metabolism, rat, 2026 Hematological toxicity, mouse Bleomycin, 1341 Uridine diphosphoglucose:galactose-l- 4282 Walker 256 tumor cells phosphate uridyltransterase Bleomycin, 1341 Urea, (chloro-2-ethyD-l-ribopyranosyl- Hepatoma, Morris 3-nitroso- Metabolism, rat, 2026 Antineoplastic agents Urea, hydroxy- Uridine, 5-fluoro-2'-deoxy- Hematological toxicity, mouse Syrian hamster embryo cells Carcinoma, Ehrlich tumor 4282 Cell transformation, neoplastic Antineoplastic activity, in vivo/in 2411 Urea, l-(2-chloroethyl)-3-cyclohexyl-l- vitro, 3333 nitroso- Thymidine incorporation, 2411 Pyrimidine nucleoside phosphory- Cytosine, l-/3-arabinofuranosyl- Amphotericin B lases L1210 leukemia cells, 3286 Antitumor activity potentiation, Isolation and characterization Mouse, in vivo/in vitro, 3286 mouse, 939 507 Fibroblasts, 3T3 Glioma(s) Substrate specificity, 507 Selective killing, 293 Biodistribution, rat, 3473 Thymidine Hydrocortisone Uracil, 5-fluoro-, 1543 Chromatin, binding, 3697 Urea, JV-methyl-./V-nitroso- Uridine, 5-iodo-5'-amino-2',5'-dideoxy- Hyperthermia Acetamide, JV-fluoren-2-yl Immunosuppression Ependymoblastoma, 2726 Liver neoplasms, 1112 Immune response, mouse, 3491 Synergestic action, mouse, 2726 Preneoplastic hepatocytes, rat Uridine, 5-iodo-2'-deoxy- L1210 cells 1112 DNA repair, 50 Chinese hamster ovary cells Immunosuppression Proteinase K, 50 DNA repair, 2623 Immune response, mouse, 3491 RNA .synthesis Mutagenicity, 2623 Uridine, 5-iodo-2'-deoxy,5'- Ependymoma, 939 Colonie neoplasms /3-Sitosterol, 403 triphosphate Urea, l-(2-chloroethyl)-3-(2,6-dioxo-3- Ribonucleotide reducÃase piperidyI)-1-nitroso- Estrogen Molt-4F lymphoblast cells, 3555 Receptors, hormone, 235 Solid tumors Mammary neoplasms Uridine kinase Phase I clinical trial 3750 Dosage schedule, rat, 235 Nucleic acid synthesis Urea, l-(2-chloroethyl>-3-(l -<5-p-nitro- Growth, rat, 4628 Lung neoplasms, 2295 benzoyl-2 ,3 -isopropylidene)-a,/3-D- Ovariectomized rat, 3112 Uridine, 5-fluoro-2'-deoxy-,5'- ribofurannsyl) 1-nitroso- Ovariectomy, 4628 monophophate Antineoplastic agents Prolactin, 3095 Uracil, 5-fluoro- Receptors, hormone, 4628 Pharmacokinetics, mouse/rat Thymidylate synthetase, 1431 3351 Retinoic acid, 47 Retinoids, 3095 Uridine, tetrahydro- Urea, N-ethyl-JV-nitroso- Tamoxifen, 235 Leukemia(s) Tumor growth vs receptor levels, Cytosine, 1-/3-D-arabinofuranosyl- Chinese hamster ovary cells rat, 3232 2441 DNA repair, 2623 Ultrastructure, 3112 Mutagenicity, 2623 Urine Retinyl acetate DNA Bladder neoplasms DNA synthesis, 1109 Immunological assays, rat, 887 Formamide, N-(4-(5-nitro-2- Trachea! neoplasms DNA synthesis furyl)-2-thiazolyl)-, 4524 Cannula system, 609 Partial hepatectomy, 1538 Morphogenesis, Syrian golden Urogenital neoplasms Epithelium hamster, 609 Lymphocytes Trachea, rat, 2898 Absolute lymphocyte count, 4612 Gonadectomy Uridine Density gradient-purified cell sus Hepatocarcinogenesis, mouse N-(Phosphonacetyl)-L-aspartate pensions, 4612 1538 Phase I clinical trial, 2938 Prognosis, 4612 Hormones Serum, humans, 2938 Retinol Hepatocarcinogenesis, mouse Uridine-cytidinekinase Binding, in vitro, 4221 1538 LI210 leukemia cells Partial hepatectomy Urokinase Inhibitory pyrimidine nucleosides Hepatocarcinogenesis, mouse Lung neoplasms 3559 1538 Plasminogen activators, 841 Isozymes, 3559 Toxoplasma gondii Plasminogen activators Nervous system neoplasms, 1240 Uridine, deoxy- Anti-urokinase antibody, 933 X-rays H-Pyrazolo(3,4-d)pyrimidin-4-ol Molecular species, normal/

4926 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

Urokinase (cont'd) Virus, adeno 2 Virus, Friend polycythemia (cont'd) neoplastic/embryonic human Cell transformation, viral Virus, spleen focus-forming cells, 933 RNA, viral, 3177 Virus production assay, 1150 Xeroderma pigmentosum Vaccines Antigens, viral, 3945 Virus, Gross murine leukemia Leukemia L1210 Host-cell reactivation, 3945 Leukemia(s) Carrageenan, 3832 Ultraviolet rays, 3945 Animal model, mouse CNS inva Immune response, mouse, 3839 sion, 3130 Mitomycin C, 3839 Virus, bovine leukemia Lymphoma(s) Potentiation immune response, Receptors, hormone Immune response, rat, 448 mouse, in vivo, 3832 Glucocorticoids, 2240 Runting syndrome, 448 Suppressor cells, 3832 Virus, herpes simplex 1 Vasoactive intestinal peptide Virus, cytomegalo Cervix neoplasms Colonie neoplasms Antibodies, neoplasm, 4640 Adenosine cyclic 3':5'- Mammary neoplasms Host resistance, mouse, 853 Antibodies, viral, 4640 monophosphate, 2529 Neoplasm mÃ©tastases Virus, herpes simplex 2 Host resistance, mouse, 853 Antibodies, viral Vibrio succinogenes Serum, rat, 2074 Asparaginase Cell transformation, neoplastic Plaque-forming cell assay, 1125 Virus, Epstein-Barr Ultraviolet rays, 2213 Cell transformation, viral Viral proteins, 2213 NL2/NL3/NL4 lymphoblastoid Vinblastine Virus, SV40, 2213 cells, 4775 L1210 cells Cell transformation, viral Fusobacterium nucleatum Cell proliferation, 2695 Antibodies, viral, 2074 P3HR-1 human lymphoblastoid Antigens, viral, 2074 Vincristine cells, 4329 Cell surface proteins, 713 L1210 cells Total hemolytic complement, Cell proliferation, 2695 serum, hamster, 713 Cerebrospinal fluid Virus, Epstein-Burkett REI cells Neurotoxicity, 722 Leukemia(s) Antigens, viral, 2074 Pharmacokinetics, rhesus monkey Review, 3405 Cervix neoplasms 722 Lymphoma(s) l-Propargyl-5-chlororpyrimidin-2-one Review, 3405 Antibodies, neoplasm, 4640 Antibodies, viral, 4640 Cell cycle kinetics, 2069 NHIK 3025 cells, 2069 Virus, feline leukemia Virus, Kirsten murine leukemia Vindesine Antibodies, neoplasm Cytochalasin B Adenosine cyclic 3':5'- Isolation and characterization Tumorigenicity/soft agar cell monophosphate, 2695 3642 growth, 4410 Antigens, neoplasm L1210 cells Antibodies, neoplasm, 3642 Virus, Kirsten murine sarcoma Cell proliferation, 2695 Complement-dependent antibody Cytochalasin B Vinyl carbamate Immune response, young/adult Tumorigenicity/soft agar cell see Carbamic acid, vinyl ester cat, 823 growth, 4410 Natural infection, 823 Virus, lactate dehydrogenase Vinyl chloride Adenoma(s) see Ethylene, chloro- Carbamic acid, ethyl ester, 64 Virus, Friend murine leukemia Immune response, mouse, 64 Virai activation Cell transformation, viral Lung neoplasms Virus, type C 3BM-78 cells, 866 a-Amanitin, 22 Carbamic acid, ethyl ester, 64 Erythroblasts Immune response, mouse, 64 Cell permeabilization technique Ultrastructural study, 1150 22 Lymphoma(s) Virus, Moloney murine leukemia Transcriptional control, 22 Immune response, rat, 448 Cytochalasin B Tumorigenicity/soft agar cell Viral proteins Runting syndrome, 448 growth, 4410 Antibodies, viral Macrophages Microcytotoxicity assay, human Immune response, mouse, 557 Virus, Moloney murine sarcoma fluids, 166 Cytochalasin B Radioimmunoprecipitation, 166 Passive serum therapy, 557 12-O-Tetracanoylphorbol-13-acetate Tumorigenicity/soft agar cell Cell transformation, neoplastic growth, 4410 Virus, herpes simplex type 2 Plasminogen activator, 3369 Virus genonme expression, 3369 2213 Virus, murine leukemia Virus, SV40, 2213 Virus, Friend polycythemia Virus production assay, 1150 Fibrosarcoma(s) Virus, Abelson Cross-protection, mouse, 1036 Infected, neonatal/adult mouse Virus, Friend polycythemia Hybrid cells Leukemia-associated inhibitory Virus, Friend murine leukemia Cytotoxicity, lymphocytes virus- activity, 3928 Virus production assay, 1150 producing, 3850

DECEMBER 1980 4927 Subject Index to Volume 40

Virus, murine leukemia (cont'd) Virus, SV40 Vitamin E RNA-complementary DNA hybridi Cell transformation, neoplastic see a-Tocopherol zation analysis Viral proteins, 2213 Weibel-Palade bodies Fetal/young/aged mouse, 519 Virus, herpes simplex type 2 Brain neoplasms 2213 Angiogenesis, 2010 Virus, murine mammary tumor Cell transformation, viral Breast neoplasms Antigens, fetal, 1380 Diagnosis, 2010 Cells, human, 3880 Antigens, neoplasm, 1380 Wheat germ agglutinili Mammary neoplasms Antigens, surface, 1380 Macrophages Adenocarcinoma(s), 368 Benzaldehyde, 2574 C3H/He mammary carcinoma Biology/virology/tumorigenicity, 3T3 cells, 3089 cells, 3798 five cell lines, 4232 Neoplasm transplantation, 1380 MH134 hepatoma cells, 3798 Hyperplastic alveolar nodules, Retinoic acid, 3089 MM48 mammary carcinoma cells mouse, 4232 RNA, viral, 3177 3798 MÃ©tastases Fibroblasts, 3T3 Tumor cell lysis, 3798 DNA-RNA hybridization, 2316 Transformation, viral, 293 WR-2721 Virus, Newcastle disease Virus, type A see Phosphorothioic acid, S-2-(3- Interferon Sarcoma, osteogenic aminopropylammo)ethyl- L cells, 2919 Transformation, viral, 127 X-rays Virus, oncorna, 127 Virus, oncorna Anthraquinone, 1,8-hydroxy- Sarcoma, osteogenic Virus, type C Cell cycle kinetics, 42 Virus, type A, 127 Adrenal gland neoplasms Antineoplastic agents Virus, type C, 127 Ovariectomy, 3570 Cell survival assay, mouse, 145 Antibodies, viral Growth inhibition, 145 Virus, polyoma Microcytotoxicity assay, human Autochthonous tumors Cell transformation, viral fluids, 166 Radioresistance, mouse, 2547 RNA, viral, 3177 Radioimmunoprecipitation, 166 Cell transformation, neoplastic Virus, radiation leukemia Inclusion bodies, viral Ultraviolet rays, 582 C57BL/Ka lymphoid cells Letter to the editor, 1765 Lymphoid cells Quantitative assay, 544 K-BALB 16c cells Splenectomy and/or irradiated Target cells, thymus/spleen/bone Cell permeabilization technique nude mouse, 2588 marrow, mouse 22 Transplantation, heterologous Quantitative assay, 544 Sarcoma, osteogenic 2588 Transformation, viral, 127 NHIK 3025 carcinoma cells Virus, Rauscher murine leukemia Virus, oncorna, 127 DNA single strand, 2915 Erythropoieses Viral activation Sister chromatid exchanges, 2915 Infected mouse, 4270 a-Amanitin, 22 Diethylstilbestrol Virus, retro- Cell permeabilization technique Mammary neoplasms, 3966 Breast neoplasms 22 Synergistic carcinogenesis, rat Cells, human, 3880 Transcriptional control, 22 3966 DNA repair Virus, Rous sarcoma Virus, xenotropic Ultraviolet rays, 582 Cell transformation, viral Carcinogenesis, chemical Fibroblasts Adenosine cyclic 3':5'- Susceptibility vs virus production, Chromosome aberrations, 920 monophosphate-independent mouse, 4364 Clonogenic survival assay, 920 protein kinase, 1733 Genetics Hereditary diseases, 920 BHK cells Susceptibility vs virus production, Fibrosarcoma(s) Cell transformation, viral, 1550 mouse, 4364 Cholanthrene, 3-methyl-, 2547 Cytochalasin B Vitamin A L1210 cells Tumorigenicity/soft agar cell see Retinol DNA repair, 50 growth, 4410 Lymphoma(s) Fibroblasts Vitamin A analogs Bone marrow reconstitution, Medium change response, chicken see Retinoids mouse, 357 1753 Vitamin C Somatic cell damage, children Ornithine decarboxylase see also Ascorbic acid 4786 Rat-1 fibroblasts, 604 HT 1080 fibrosarcoma cells Spleen cell reconstitution, mouse Phosphoprotein ppoOSRC 357 Adenosine cyclic 3':5'- Extracellular matrix digestion 3228 Suppressor cells monophosphate-independent Smooth muscle cells, rat Blood levels, cancer patients protein kinase, 1733 Extracellular matrix digestion 3134 12-O-Tetradecanoylphorbol-13- Virus, spleen focus-forming 3228 acetate Erythroblasts Vitamin D,, 1,25-dihydro- Carcinogenicity enhancement Ultrastructural study, 1150 Human breast cancer cells 1915 Virus, Friend polycythemia Human breast epithelial cells Thymus neoplasms Virus production assay, 1150 4764 Immunodepression, 357

4928 CANCER RESEARCH VOL. 40 Subject Index to Volume 40

X-rays (cont'd) Xenograft Xeroderma pigmentosum (cont'd) Urea, ethylnitroso- see Transplantation, heterologous Epidemiological study, Egypt, 13 Transplacental carcinogenesis, rat DNA repair 3973 Xeroderma pigmentosum Epidemiological study, Egypt, 13 Angelicin 8-Methoxypsoralen Xanthine, l-methyl-3-isobutyl- DNA repair, 696 DNA repair, 696 Cyclohcximide CRL 1121/1221/1223 fibroblast cells Ultraviolet rays Monocytes, 1955 Acetamide, AT-(acetyloxy)-JV-9-//- DNA repair, 2736 Phosphodiesterase fluoren-2-yl, 4313 Virus, adeno type 2 Enzyme activity, human, 1955 Clinical characteristics Antigens, viral, 3945 Phosphodiesterase inhibitors Epidemiological study, Egypt, 13 Host-cell reactivation, 3945 Growth inhibition, 1950 Complementation groups Ultraviolet rays, 3945

DECEMBER 1980 4929 Contents of Volume 40, 1980

January, Number 1

1 An Evaluation of Chemicals and Industrial Processes 67 Activation of Nitrosamines to Mutagens by Posimi- 139 Effect of Methotrexate on 5-Phosphonbosyl 1-Pyro- Associated with Cancer in Humans Based on Human tochondrial Fraction of Hamster Pancreas. Dante G phosphate Levels in L1210 Leukemia Cells in Vitro. and Animal Data: IARC Monographs Volumes 1 to 20. Scarpelli. M Sambasiva Rao. Vadrevu Subbarao Marc Jose M Buesa-Perez, Albert Leyva. and Herbert M Report of an IARC Working Group, prepared by Ralph Beversluis, David P Gurka, and Paul F Hollenberg Pinedo Althouse. James Huff. Lorenzo Tomatis, and Julian 75 Effects of Thioacetamide Treatment on Nuclear En 145 Single-Agent Chemotherapy of a Solid Murine Tumor Wilbourn velope Nucleoside Triphosphatase Activity and Assayed by Growth Delay and Cell Survival. Adrian Transport of RNA from Rat Liver Nuclei. Gary A C Begg. Karen K Fu, Lawrence J Kane, and Theodore *13 Clinical Characteristics. DNA Repair, and Comple Clawson. Marlene Koplitz. David E Moody, and Edward L Phillips mentation Groups in Xeroderma Pigmentosum Pa A Smuckler tients from Egypt. Nemat Hashem. Dirk Bootsma. 155 Two-Stage Tumorigenesis of Dermal Melanocytes in 80 Relationship of Bacillus Ca/meffe-Guenn-induced Wilma Ketzer, Arthur Greene. Lewis Conell. Gregory the Back Skin of the Syrian Golden Hamster Using Thomas, and James E Cleaver Suppressor Cells to Hematopoietic Precursor Cells. Systemic Initiation with 7.12-Dimethylbenz{a}an- James A Bennett and John C Marsh thracene and Topical Promotion with 12-O-Tetra- 19 Carcinogenicity in Rats of Nitrosomethylethylamines *86 Pharmacological Disposition of W-(Phosphonacetyl)- decanoylphorbol-13-acetate. K Goerttler, H Loehrke, Labeled with Deuterium in Several Positions. William L-aspartate in Humans. Ti Li Loo. Jacqueline Friedman, J Schweizer, and B Hesse Lijinsky and Melvm D Reuber E Colleen Moore. Manuel Valdivieso, Jose R Marti, 162 Synthesis and Mutagenicity of 4-(N-Butylnitrosa- and David Slewart mmo)-4-hydroxybutyric Acid Lactone. a Possible 22 Analysis of Transcription during Type C Viral Induc 91 A Preneoplastic Stage in the Spontaneous Neoplastic Activated Metabolite of the Proximate Bladder Car tion Using Cell Permeabilization Techniques. C W Transformation of Syrian Hamster Embryo Cells in cinogen rV-Butyl-nf-{3-carboxypropyl)nitrosamme. Long, J A Bruszewski. and R M Snead Culture. J Carl Barrett Masalaka Mochizuki. Charles C Irving, Takako AnÂ¡o. Yuko Wakabayashi. Emako Suzuki, and Masashi 26 Insignificant Tumor Bed Etlect after Pretransplanta- 95 Growth of Human Breast Carcinomas in Nude Mice Okada tion Hypecthermia. Muneyasu Urano and Mary and Subsequent Establishment in Tissue Culture. Cunningham Barbara Rae-Venter and Lola M Reid 166 Detection of Antibodies Cross-Reactive with Type C 101 Characterization of Pulmonary Arene Oxide Biotrans RNA Tumor Viral p3O Protein

February, Number 2

203 Tumorigemc Activity of Benzo(e)pyrene Derivatives 221 Respiratory and Calcium Transport Functions of Mi 240 Antagonism between Phorbol Mynstate Acetate and on Mouse Skin and in Newborn Mice. Mildred K tochondria Isolated from Normal and Transformed Butyric Acid on Isoproterenol Elevation of Cyclic Buening. Wayne Levin. Alexander W Wood. Richard L Human Lymphocytes. Ugo Carpentieri and Louis A Adenosine 3':5'-Monophosphate and Their Effects on Cnang. Roland E Lehr. Charles W Taylor. Haruhiko Sordahl /f-Adrenergic Receptors in Mouse Epidermis. Sidney Yagi. Donald M Jenna. and Allan H Conney Belman and Seymour J Garte 225 Effects of Cesalin on the Ultrastructure and Biological 207 Metabolism and Macromolecular Binding of Carcino 245 Photo-induced Reactions of Benzo( ajpyrene with genic and Noncarcinogenic Metabolites of Benzo- Properties of Cultured Mammalian Cells. Virginia L DNA m Vitro. G F Sirniste. E MartÃnez.A M MartÃnez (ajpyrene by Hamster Embryo Cells. Gerald M Cohen Shepherd. Dale D Vandre. James J Eltmg, and Rex and R J Brake Michael C MacLeod. Cynthia J Moore, and James K Montgomery Selkirk 232 Inhibition of Polycyclic Aromatic Hydrocarbon-in 253 Hyperthermic Peritoneal Perfusion System m Ca 212 Relationship between Binding Affinities to Cellular duced Neoplasia by Sodium Cyanate. Lee W nines. John S Sprat!, Robert A Adcock. William Retinoic Acid-binding Protein and in Vivo and in Vitro Wattenberg Sherrill. and S Travathen Properties for 18 Retinoids. Palrick W Trown. Alicia V Palleroni. Oksana Bohoslawec. Barbara N Richelo. 235 Influence of Dosage Schedule on the Biological Char * 256 Clinical Delivery System for Intrapentoneal Hyper- Judith M Halpern, Nicholas GIZZI.Robert Geiger. Carol acteristics of N-Nitrosomethylurea-mduced Rat Mam thermie Chemotherapy. John S Spraft. Robert A Lewmskr. L J Machlm, Anton Jetten, and MER mary Tumors. David P Rose. Brian Pnj'tt. Patricia Adcock. Marie Muskovm. William Sherrill. and John Jetten. Stauber, Erdogan Erturk. and George T Bryan McKeown

DECEMBER 1980 Contents of Volume 40, 1980

261 Morphological Effects of Mitomycin C Administered 347 Adhesion Characteristics of Murine Metastatic and 432 Enhancement ot Hyperthermia-induced Cytotoxicity Intravesically to Normal Mice and Mice with fV (4-i5 Nonmetastatic Tumor Cells in Vitro. J Clifford Murray, by Polyamines. Eugene W Gerner, David K Holmes. Nitro iMu'yh

March, Number 3

497 Circulating Immune Complexes in Cancer Patients 535 Antitumor Activity of t-Canavanine against L1210 567 Phase I and Pharmacological Studies of 5-Fluorour- Receiving Goat Radiolocalizing Antibodies to Carci- Murine Leukemia. Melvm H Green. Timothy L acil Administered Intraperttoneally. James L Speyer. noembryonic Antigen. F James Pnmus. Sidney J Brooks. John Mendelsohn, and Stephen B Howelf Jerry M Collins, Robert L Dednck. Murray F Bennett, E Edmund Kim. Frank H DeLand. Melanie Brennan. Alan R Buckpitt, Harold Londer, Vincent T C Zahn, and David M. Goldenberg 538 Contrasting Effects of Subtotal Enteric Bypass. En DeVita. Jr. and Charles E Myers terectomy. and Colectomy. on A2oxymethane-in- 5O2 Radioimmunodetection ol Primary and Metastatic duced Intestinal Carcinogenesis. Robin C. N Ovarian Cancer Using Radioiabeled Antibodies to 573 Transport. Binding, and Polyglutamation of Metho- Williamson, Frederick L R. Bauer, Onno T. Terpstra, Carcinoembryonic Antigen. John R van Nagell, Jr.. trexate in Freshly Isolated Rat Hepatocytes. David Jeffrey S Ross, and Ronald A. Malt. Euishm Kim. Scott Casper, F James Primus. Sidney A Gewirlz. J Courtland White, Joyce K Randolph, Bennett, Frank H DeLand, and David M Goldenberg 544 Detection of Infectious Centers in C57BL/Ka Lymph- and I. David Goldman 507 Specificity ot Pyhmidine Nucleoside Phosphorylases oid Cell Populations Infected in Vitro by the Radiation and the Phosphorolysis of 5-Fluoro-2'-deoxyuridine. Leukemia Virus. Jacques Boniver. Alain Decleve. 579 Transplantation of Primary Plasma Cell Tumor with out 2,6,10,14-Tetramethylpentadecane (Pnstane) Peter W Woodman. Awni M Sarnf. and Charles Olivera J. Finn. Cyril Honsik. Miriam Lieberman, and Heidelberger Henry S Kaplan Treatment of the Hosts. M Platica. C Bo(ko. and V P Hollander 512 Explantation and Subculture of Epithelial Cells from 55O Secretion of Proteinases from Malignant and Non- Human Uterine Ectocervix. Ervo H Vestermen. John malignant Human Breast Tissue, Anneliese D 582 Excision and Postreplication DNA Repair Capacities. G Nedrud. Albert M. Collier. Leslie A. Walton, and Recklies. Kathenne J Tiltman. T Allan M Stoker, and Enhanced Transformation, and Survival of Syrian Joseph S Pagano A Robin Poole. Hamster Embryo Cells Irradiated by Ultraviolet Light. 519 Regulation of Endogenous Murine Leukemia Virus- Jay Doniger and Joseph A DiPaolo related Nuclear and Cytoplasmic RNA Complexity in 557 Absence of Macrophage Involvement in the Passive C57BL/6J Mice of Increasing Age. Dagne L. Fiorine. Serum Therapy of Friend Leukemia Virus-induced 588 Ouantitation of 1-/f-r>Arabinofuranosylcytosine 5'- Tetsuya Ono. Richard G Cutler, and Michael J Getz Disease. Jeffrey J Collins and Ralph Snyderman. Triphosphate in the Leukemic Cells from Bone Mar 524 Chromosomal Analysis of Human Prostatic Adeno- row and Peripheral Blood of Patients Receiving carcinoma Cell Lines. Yasushi Ohnuki. Maureen M 563 Glucocorticoid Sensitivity and Receptors in Celts of 1-/J-r>Arabinofuranosylcytosine Therapy. William Mameli, Merrill S Babcock. John F Lechner, and M. Human Myelogenous Leukemia Lines. H Phillip Plunkett, Verena Hug, Michael J Keating, and Shern Edward Kaighn Koeffler. David W Golde, and Marc E Lippman. Chubb

iv CANCER RESEARCH VOL. 40 Contents of Volume 40, 1980

592 Armar Cell Carcinoma of the Rat Pancreas Grown in 717 Inhibition of Growth of Colorectal Carcinoma in Nude 866 Cytochemical Characteristics of Leukopoietic Differ Cell Culture and in Nude Mice. K N Rao, Senchi Mice by Monoclonal Antibody. DorothÃ©eM Herlyn, entiation in Murtne Erythroleukemic (Friend) Cells. Takahashi. and Hisashi Shmozuka Zenon Steplewski, Meenhard F Herlyn. and Hilary Giuseppe Fiontoni, Luisa Bertolmi. Glauco Torlontano. Koprowski and Roberto Revoltella 598 Antitumor Activity of Cytidme Dialdehyde and Its Effects on Nucleotide and Nucleic Acid Synthesis. 722 Pharmacokinetics of Vincristine in the Cerebrospinal 873 Impaired Induction of Type M Interferon in Tumor- James J Kinahan. Zlatko P Pavelic. Robert J Fluid of Subhuman Primates. Don V Jackson, Jr . bearing Mice. Shuzo Matsubara, Midori Suzuki, and Leonard. Alexander Bloch, and Gerald B Grindey Manford C Castle, David G Poplack, and Richard A Nakao Ishida Bender 6O4 Ornithme Decarboxylase Induction during G, Pro 877 Ammotransferase Activities and Involution of the gression of Normal and Rous Sarcoma Virus-trans 725 Phenotypic Diversity as an Early Property of Putative Thymus in Rats Bearing AH 130 Tumors. Fumihide formed Cells. Man K Haddox. Bruce E Magun, and Preneoplastic Hepatocyte Populations in Liver Car- Isohashi. Kazue Tsukanaka. Masako Terada. Yoko Diane Haddock Russell cmogenesis. KatSuhiro Ogawa, Dennis B Solt. and Nakamshi. Sadanao Tam. and Yukiya Sakamoto Emmanuel Farber 609 Morphogenesis of Neoplasms Induced in the Hamster Trachea with W-Methyl-Af-nitrosourea. Sherman F 734 Saccharin-induced Hyperplasia of the Rat Urinary 882 Mutagenic and Carcinogenic Metabolites of the Stmson and Juliet C Lilga Bladder. Shoji Fukushima and Samuel M Cohen Carcinogen 15.16-Dihydro-11-methylcyclopenta[a}- phenanthren-17-one. Maurice M Coombs. Tarlochan 614 Inhibition of Growth of B16 Murine Malignant Mela 737 Cell Kinetic-directed Sequential Chemotherapy with S Bhatt, Anna-Maija Kissonerghis. and Colin W noma by Exogenous Interferon. Robert S Bart. Cyclophosphamide and Adriamycin in T1699 Mam Vose Nancy R. Porzto, Alfred W Kopf. Jan T Vilcek. mary Tumors. Paul G Braunschweiger and Lewis M Edward H Cheng, and Yolaine Farcet. Schiffer 887 Immunological Quantification by High-Affinity Anti bodies of O*-Ethyldeoxyguanostne in DNA Exposed 620 Comparisons of Liver Transfer RNA Methyltransfer- 744 Relative Activities of Thymidylate Synthetase and to Af-Ethyl-nf-nitrosourea. Rolt Muller and Manfred F ase and Adenosylmethionine Decarboxylase Activi Thymidine Kinase in Rat Tissues. Annemarie Rajewsky. ties of Male and Female Rats. E Wamfan, H Brody, Herzfeld and Suzanne M RÃ¢per N M Relyea. and M. E Balis 751 Metabolic Activation of rV-Hydroxy-rV.AT-diacetylben- 897 Adaptation of Mass Spectrometry for the Analysis of 625 Enhanced Experimental Metastasis of Ultraviolet zidine by Hepatic Sulfotransferase. Kenneth C Tumor Antigens as Applied to Blood Group Glycolip- Light-induced Fibrosarcomas in Ultraviolet Light-ir Morton. Frederick A Beland. Frederick E. Evans. ids of a Human Gastric Carcinoma. Michael E radiated Syngeneic Mice. Margaret L Knpke and Nancy F. Fullerton. and Fred F Kadlubar Breimer Isaiah J Fidler 758 Isolation from Murine Myeloma and Leukemia Cells 9O9 Comparative Study of the Phospholipid Composition 630 Effect of Cholesterol Content on Antitumor Activity of a Selective Inhibitor of DNA Polymerases. A of Plasma Membranes Isolated from Rat Primary Hep- and Toxicity of Liposome-encapsulated 1-/f-o-Arabi- Arthur Gottlieb. Judy Chang. D Paul Buhrer, and atomas Induced by 3'-Methyl-4-dimethylaminoazo- nofuranosylcytosine in Vivo. Ram Ganapathi. Awtar Barbara A Brennessel benzene and from Normal Growing Rat Livers. Kmya Knshan, Isidore Wodinsky, C Gordon Zubrod. and Koizumi. Keiko Tamiya-Koizumi. Tatsuzo FuiÂ».Jun 771 Radiation Synergism by Repair-inhibiting Nitrosou- Lawrence J Lesko Okuda. and Kiyohide Kojima reas in L1210 Cells. Herbert E Kann. Jr . Brent A 634 Effect of Nutritional and Enzymatic Methionme Dep Blumenstein. Atalante Petkas. and Mary Ann Schott 914 Effects of Retinoids on Induction of Differentiation of rivation upon Human Normal and Malignant Cells in Cultured Mouse Myeloid Leukemia Cells. Keizo Tissue Culture. Willi Kreis. Andrea Baker, Valerie 776 Inhibition of ^-O-TetradecanoylphorboMS-acetate- Takenaga, Motoo Hozumi. and Yoshio Sakagami Ryan, and Anne Bertasso accelerated Phospholipid Metabolism by 5.8.11,14- Eicosatetraynoic Acid. Philip W Wertz and Gerald C 642 Mutagenicity and Tumor-initiating Activity of Cyclo- 920 X-Ray Sensitivity of Fifty-three Human Diploid Fibro- Mueller pentaf r.rf Jpyrene and Structurally Related Com blast Cell Strains from Patients with Characterized pounds. Alexander W Wood. Wayne Levin. Richard 782 Relationships between Carcinogenesis in Vivo and Genetic Disorders. Ralph R Weichselbaum. John L Chang. Mou-Tuan Huang. Dene E Ryan. Paul E Alkylation and Solvolysis in Vitro. Richard M Peck Nove, and John B Little Thomas, Roland E. Lehr, Subodh Kumar. Masato and Evelyn B Peck 926 Survey of Radiosensitivity tn a Variety of Human Cell Koreeda. Hirashi Akagi. Yitzhak Utah, Patrick 786 Induction of Two Transformation-sensitive Mem Dansette. Haruhiko Vagi. Donald M Jerina. and Allan Strains. Colin F Arieti and Susan A Harcourt brane Polypeptides in Normal Rat Kidney Cells by H Conney Iron Deprivation. J A Fernandez-Pol 933 Molecular Species of Plasminogen Activators Se 650 Reversal of the in Vitro Methotrexate Suppression of creted by Normal and Neoplastic Human Cells. 796 Nonrandom Abnormalities in Chromosome 1 in Hu Cell-mediated Immune Response by Folinic Acid and Elaine Lynette Wilson. Michael L B Becker. Eileen G man Testicular Cancers. Nancy Wang. Beth Trend. Thymidine plus Hypoxanthine. Dennis Bogyo and Hoal, and Eugene B Dowdle David L. Bronson, and Elwm E Fraley Enrico Minien. 939 Inhibition of RNA Synthesis in Murine Ependymoblas- 655 Evaluation of Metabolic Activation of 7,12 Dimethyl 803 Comparative Study of the Cytoplasmic Organelles of benz(a)anthracene in Vitro by Aroclor 1254-induced Epithelial Cell Lines Derived from Human Carcinomas toma by the Combination of Amphotericin B and 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea. Guy and Nonmalignant Tissues. E Louise Springer Rat Liver S-9 Fraction. C A H Bigger. J E Laurent. Julienne Dewene-Vanhouche. David MachÃn. Tomaszewski. A W Andrews, and A Dipple 818 Clinical Phase i-li and Pharmacokinetic Study of and Jerzy Hildebrand High-Dose Thymidine Given by Continuous Intrave 662 Radioimmunoassay for Tissue Distribution of a Hu man Mammary Tumor-specific Glycoprotein. Julia P nous Infusion. Delia F Chiuten. Peter H Wiernik. 943 Effect of Anticancer Agents on Directional Migration Leung and Thomas S Edgington Daniel S Zaharko, and Linda Edwards of Malignant C3H Mouse Fibroblastic Cells in Vitro. Guy Storme and Marc M Mareel 667 Shortened Platelet Survival as a Cause of Thrombo- 823 Natural Feline Leukemia Virus Infection and the Im mune Response of Cats of Different Ages. Chris K cytopenia in Mice with L1210 Leukemia. Carl W 949 Human Embryonal Carcinoma Grown in Athymic Mice Grant. M Essex. M B Gardner, and W D Hardy. Jr Jackson, Robert A. Krance. Carol C. Edwards, and in Vitro. Kjell Magne Tveit. Oystem Fodstad. Margaret A Whidden. and Patricia A. Gauthier. 830 Resistance Patterns of Walker Carcinosarcoma 256 Anton Brogger. and Sjur Olsnes and Other Rodent Tumors to Cyclophosphamide and 671 Action of Dihydroxyanthraquinone on Cell Cycle Pro L-Phenylalanine Mustard. Franz A Schmid. Glenys 954 Effect of Normal Allogeneic Lymphoid Cell Transfer gression and Survival of a Variety of Cultured Mam M Otter, and C Chester Stock. in Combination with Chemotherapy on a Transplant- malian Cells. Frank TrÃ¡ganos, Donald P Evenson. able Tumor in Rats. YUJI Yamada. Tsugumichi Lisa Staiano-Coico. Zbigniew Darzynkiewicz. and 834 Acyltransferase-mediated Binding of nf-Hydroxyar- Kawamura. Eiki Gotohda. Jitsuo Akiyama. Masuo Myron R Melamed. ylamides to Nucleic Acids. Frederick A Beland. Hosokawa. Takao Kodama. and Hiroshi Kobayashi William T Allaben. and Frederick E Evans 682 DNA Synthesis, Mutagenesis. DNA Damage, and Cy totoxicity in Cultured Mammalian Cells Treated with 841 Content and Characterization of Plasminogen Acti 959 Letter to the Editor: Thermal Sensitivity of Murine Alkylating Agents. A R Peterson vators in Human Lung Tumors and Normal Lung Tis Tumor Cells and Hyperthermic Tumor Eradication. sue. Gabor Markus. Hiroshi Takita. Sarah M Camiolo. Correspondence re: M. Urano. H. D. Suit, P. Dunn. T. 689 Photochemically Induced Binding of Aflatoxins to Lansdale, and R. S. Sedlacek. Enhancement of the DNA and Its Effects on Template Activity. Jong- James G Corasanti. John L Evers. and Grant H Hobika Thermal Response of Animal Tumors by Corynebac- Chaur Shieh and Pill-Soon Song. terium parvum. Cancer Res.. 39 3454-3457, 1979. 849 Induction of Plasminogen Activator and Prostaglan- Muneyasu Urano and Laurie Rice 696 DNA Repair in Human Cells Containing Photoadducts din Biosynthesis in HeLa Cells by 12-O-Tetradeca- of 8-Methoxypsoralen or Angelicin. James Kaye. noylphorbol-13-acetate. David J Crutchley. Lobelia Charles Allen Smith, and Philip C Hanawalt B Conanan, and James R Maynard 961 Books Received 703 Flow Analysis of DNA Content and Cell Size in Non- Hodgkin's Lymphoma. Lawrence W Diamond and 853 Alteration of Murine Mammary Tumor Metastasis and Growth by Cytomegalovirus Infection. Gregg A 964 Announcements Raul C Braylan Olsen. Lowell A Glasgow, and Lyle A Dethlefsen 713 Depletion of Total Hemolytic Complement in Sera 861 Presence of Steroid Receptors in Human Soft Tissue 965 Errata from Hamsters Bearing Herpes Simplex Type Sarcomas of Diverse HistolÃ³gica! Origin. Prabir K J induced Tumors. Ernest D Marquez. Joan M Chaudhun. Michael J Walker. Craig W Seattle, and Backenstose. and Janet L Chapman Tapas K Das Gupta. 966 Author Index

DECEMBER 1980 Contents of Volume 40, 1980

April, Number 4

967 Influence of Chlorambucil, a Bifunctional Alkylating 1097 Relationships among Retinoid Structure, Inhibition of 1235 Activities of Some Enzymes of Pyrimidine and DNA Agent, on DNA Replication and Misione Gene Expres Growth, and Cellular Retinoic Acid-binding Protein in Synthesis in a Rat Transplantable Hepatoma and sion in HeLa S3 Cells. Siegfried Detke. Janet L Stem, Cultured S91 Melanoma Cells. Reuben Lotan, George Human Primary Hepatomas. in Cell Lines Derived and Gary S Stem. Neumann, and Dafna Lotan from These Tissues, and in Human Fetal Liver. Roger R. Cummins and Doris Balmsky 975 Influence of Surfactant Concentration on the Antitu- 1103 Effect of 2,3-Dihydro-1H-imidazo[1,2-t>]pyrazole on mor Activity of Emulsified Components of Mycobac- the Proliferation of Kjuse Leukemic and Normal 124O Influence of Chronic Toxopiasma Infection on Ethyl- teria. Eliyahu Yarkoni and Herben J. Rapp. Cells /n Vivo. Ram Ganapathi and Awtar Knshan nitrosourea-induced Central Nervous System Tumors in Rats, Frances K Conley 979 Levels of Cytotoxic Reactivity to Cultured Normal 1109 Inhibition of DNA Synthesis by Retinyl Acetate during Skin Fibroblasta In Sera from Normal and Sarcoma- Chemically Induced Mammary Carcinogenesis. 1245 Purification and Characterization of Acid Phospha- bearing Patients. Michael S Catapano. John M. Rajendra G Mehta and Richard C Moon tase from Dunning R3327H Prostatic Adenocarci- Brown, and Steven A. Rosenberg. noma. Chmg-li Lee. Gerald P Murphy, and T Ming 1112 Persistence of Resistant Putative Preneoplastic He- Chu 984 Decreased DNA Repair Synthesis and Defective Col patocytes Induced by nf-Nitrosodiethylamine or N- ony-forming Ability of Ataxia Telanglectasia Fibro- Methyl-N-nitrosourea. Dennis B Solt. Edmundo 1249 Specific Inhibition of Proliferation of Nonmalignant blast Cell Strains Treated with rV-Methyl-N'-nitro-N- Cayama. D S R Sarma, and Emmanuel FÃ¤rber Rat Hepatic Cells by a Factor from Rat Liver. J B nitrosoguanidine. Dominic A. Scudiere 1119 Binding of [3H]12-O-Tetradecanoylphorbol-13-ace- McMahon and P T lype *991 Clinical Correlations of Steroid Receptors and Male tate to Intact Human Peripheral Blood Lymphocytes. Richard D Estensen. Debra K. DeHoogh. and Clair F 1255 Tumorilysm Collected in Diffusion Chambers and Re Breast Cancer. Richard B Everson, Marc E. Lippman. Cole straint of Foreign Body Tumohgenesis. Donald J E Brad Thompson. William L McGuire. James L Ferguson and James L. Urban. Wittlitl. Eugene R DeSombre, Elwood V Jensen. 1125 Comparison of the Immunosuppressive Effects of Amnuay Smghakowmta. Samuel C. Brooks, Jr., and Asparaginases from Eschenchta coli and Vibrio suc- *1263 Clinical Pharmacokinetics of Adhamycin in Hepa James P Neifeld. cinogenes. Donald L Durden and John A Distasio toma Patients with Cirrhosis. Kenneth K Chan. Rowan T Chlebowski. Myron long. H-S George Chen, Joseph 998 Mechanism for Exclusion of 5-Fluorouracil from DNA. 1130 Role of Vascular Function in Response of Tumors in Holly A Ingraham, Ben Y. Tseng, and Mehran Goulian. Vivo to Hyperthermia. Man-Sik Kang. Chang Won F. Gross, and Joseph R Bateman Song, and Seymour H Levitt. 1002 Inhibition of DNA Synthesis and Enhancement of the 1269 Progressive DNA Damage in Hepatic Nodules during Uptake and Action of Methotrexate by Low-Power- 1136 Thermal Enhancement of DNA Damage in Mammalian 2-Acetylaminofluorene Carcinogenesis. Daniel L Cells Treated with Crs-Diamminedichloroplatinum(H). Density Microwave Radiation in L1210 Leukemia Stout and Frederick F Becker Cells. Barbara K Chang. Andrew T Huang, and William Raymond E Meyn. Peter M Corry, Susan E Fletcher, T Jomes and Mane Demetnades 1274 Effect of Thymidine on the Toxicity, Antitumor Activ tty, and Metabolism of 1-/(-D-Arabinofuranosytcyto- 1140 Inhibition of Rat Mammary Carcinogenesis by Short 1006 Demonstration of a Direct Carcinogenic Effect of sine in Rats Bearing a Chemically Induced Colon Dietary Exposure to Retinyl Acetate. David L Estradici on Leydig Cells of the Mouse. Robert A Carcinoma. Lynn L Danhauser and Youcef M Rustum McCormick. Frednc J Burns, and Roy E Albert. Huseby. 1144 Transport of Melphalan by Sensitive and Resistant 1281 Malignant Transformation of Cultured Rat Hepato 1014 Poiy(2'-0-MethyicytidyiateKHrected DNA Polymer- cytes by ( + )- and ( - )-frans-7,8-Dihydro-7,8-dihydrox- L1210 Cells. William R Redwood and Michael Colvm ase and Terminal Deoxynucleot idyl transfer ase Activ ybenzo(a)pyrene. Nicholas Hemtz, Brian Little. Edward ities in Particulate Fractions Obtained from Human 1150 Production of Spleen Focus-forming Virus and Murine Bresnick, and Warren I Schaeffer Spleens. Stuart L. Marcus and Rebecca Kopelman Leukemia Virus by Early Erythroblasts after Friend Virus Infection. Thomas A, Kost, W. David Hankins. 1286 Purine and Pyrimidine Nucleotide Patterns of Normal, 1022 Effect of Vitamin E against Adriamycin-induced Tox- A D Glick. and Sanford B Krantz Differentiating, and Regenerating Liver and of Hepa icity in Rabbits. Yeu-Mmg Wang, Farns F Madanat, tomas in Rats. Robert C Jackson. May S. Lui, 1157 Induction of Resistant Hepatocytes as a New Princi Jim C. Kimball. Chester A Gleiser. Mohamed K Ali. ple for a Possible Short-Term m Vivo Test for Carcin Theodore J. Bontzki, Harold P Morns, and George Michael W Kaufman, and Jan van Eys. Weber. ogens. Hiroyuki Tsuda. George Lee. and Emmanuel Farber. 1028 Modulation of Phagocytosis by Tumor Promoters and *1292 Sister Chromatid Exchange and Growth Kinetics of Epidermal Growth Factor in Normal and Transformed 1165 In Vitro Thermochemotherapy of Human Colon Can Marrow Cells in Aneuploid Acute Nonlymphocytic Macrophages. Debra L Laskin. Jeffrey D Laskm. I cer Cells with cis-Dichlorodiammineplatinum(ll) and Leukemias. Syuiti Abe and Avery A Sandberg Bernard Weinstein, and Richard A Carchman. Mitomycin C. Barthel Barlogie. Peter M Corry. and Benjamin Drewmko * 1300 Serum Sialyltransferase Levels as a Parameter in the 1036 Immunoprophylaxis of Syngeneic Methylcholan- Diagnosis and Follow-up of Gastrointestinal Tumors. threne-induced Murine Sarcomas with Bacillus Cal- 1169 L-Phenylalanine Mustard (Melphalan) Uptake and Ulrich Ganzmger and Erwin Deutsch mette-Guerin and Tumor Cells. B Zbar. G Canti. Cross-Linking in the RPMI 6410 Human Lymphoblas- H J Rapp. M P Ashley. S Sukumar. and R C Bast. toid Cell Line. L W. Brox. 8 Gowans. and A Belch 1305 High-Pressure Liquid Chromatographie Analysis of Jr 1173 An in Vitro and in Vivo Investigation of Three Surface- Benzo( a)pyrene Metabolism by Human Lymphocytes 1043 Tissue Disaggregation of Human Renal Cell Carci active Agents as Modulators of Cell Proliferation. from Donors of Different Aryl Hydrocarbon Hydro* noma with Further Isopyknic and Isokinetic Gradient Jerry Tobler. Mark T Watts, and Juian-|uian L Fu ylase Inducibility and Antipyrine Half-Lives. H L Purification. George P Hemstreet III, Patricia G 1181 Partial Purification of Carcinoembryonic-Reactive An Gurtoo. J B. Vaught, A. J. Mannello. B. Paigen, T Enoch, and Thomas G Pretlow II Gessner. and W Bolanowska tigen from Breast Neoplasms Using Lectin and Anti body Affinity Chromatography. Richard J. Santen. 1050 The Biological Significance of Estradiol Receptor 1311 Properties of a Calcitonin Receptor and Adenylate Julien Collette, and Paul Franchimont Binding to DNA. Sukur Khan. Mark Feldman. and Cyclase in BEN Cells, a Human Cancer Cell Line. Vincent P Hollander 1189 Increase of Sister Chromatid Exchanges and Pertur David M. Findlay. Mario deLuise, ValdoP. Michelangeli, bations of Cell Division Kinetics in Human Lympho Morag Ellison, and T. John Martin 1054 Apparent Autophagocylosis of Mitochondria in cytes by Benzene Metabolites. Kanehisa Monmoto L1210 Leukemia Cells Treated in Vitro with 4.4 -Di- 1318 Cell Surface Adenosine S'-Triphosphatase as an in acetyl-diphenylurea-bis(guanylhydrazone). F Mikles- and Sheldon Wolff. Vitro Marker of the Lineage and Cytodifferentiation Robertson, C Dave, and Carl W Porter 1194 Comparative Carcinogenicities and Mutagenicities of of Oncogenic Epithelial Cells from Rat Liver Paren Vinyl Carbamate, Ethyl Carbamate, and Ethyl W-Hy- 1O62 Growth Suppression of Human Leukemic Cells in chyma. Shuichi Karasaki. Martha H Suh. Milagros Vitro by L-Ascorbic Acid. Chan H Park, Mammo droxycarbamate. Gary A Dahl. Elizabeth C. Miller, and Salas, and Jean Raymond Amare, Michael A. Savin, and Barth Hoogstraten James A. Miller 1329 Effect of Dietary Vitamin E on Dimethyl h ydrazine- 1204 Effects of Structure of N-Acyl-N-2-fluorenylhydrox- 1066 Activity of Phorbol Ester Tumor Promoters on Enucle induced Colonie Tumors in Mice. Martin G Cook and ylamines on Arylhydroxamic Acid Acyltransferase, ated Swiss 3T3 Cells. Denise S Nagle and Peter M Peter McNamara Sulfotransferase, and Deacylase Activities, and on Blumberg Mutations in Salmonella typhimurium TA 1538. 1332 Timing of Chemically Induced Neoplasia in Mice Re 1073 Comparative Tumor-initiating Activity of Methylated Charles E. Weeks. William T. Allaben. Nancy M. Tresp. vealed by the Antineoplastic Action of Caffeine. Benzol aÃPyrenÂ«Derivatives in Mouse Skin. R P Iyer. Shirley C. Louie, Edward J Lazear, and Charles M Taisei Nomura. King J W Lyga.J A Secnst III, G H Daub, and T J. Slaga. 1341 Combination Chemotherapy with 1 (4-A mi no-:? 1077 Circumvention of Resistance to Daunorubicin by N- 1212 Platelets as a Source of Growth-promoting Factor(s) methyl-5-pyrimidinyl)methyl-3-{2-chloroethyl)-3-nitro- Acetyldaunorubicin in Ehrlich Ascites Tumor. Torben for Tumor Cells. Y HarÃ¡. M Steiner, and M G Baldini sourea Hydrochloride and Bleomycin in Meningea! Carcinomatosis in Rats. Keiji Shimizu. Yukitaka Ushio. Skovsgaard 1217 Characterization of the Platelet-aggregating Activity Toru Hayakawa. and Heitaro Mogami 1084 Effect of Fatty Acid Modifications of Cultured Hepa- of Tumor Cells. Yoshikuni HarÃ¡, Manfred Sterner, and 1344 Effect of Liposome encapsulated Ouercetin on DNA toma Cells on Susceptibility to Complement-me Mano G Baldini Synthesis, Lactate Production, and Cyclic Adenosine diated Cytolysis. Tai-June Yoo. HuÃChong ChiÃ¹. Arthur 1223 Effects of Cyclic Nucleotides and Prostaglandins on 3':5'-Monophosphate Level in Ehrlich Ascites Tumor A Spector. R Stephen Whiteaker. Gerene M Denning, Normal and Abnormal Human Myeloid Progenitor Pro Cells. Osvaldo L Podhajcer, Michael Friedlander, and and Nita F Lee liferation. Raymond Taetle and Ann Koessler Yosef Oraziani

1O91 Effect of High-Dose Progesterone on Growth of Rat 1230 Pharmacokinetic Basis for Differences in Methotrex 1351 Erythrocyte Entrapment of Daunomycin by Amphc- Mammary Carcinoma. E J Diamond. S Koprak, and ate Sensitivity of Normal Proliferative Tissues in the tericin B without Hemolysis, Takeshi Kitao and Kentchi V P Hollander Mouse. F M Sirotnak and D M Moccio Hatton

VÃŒ CANCER RESEARCH VOL. 40 Contents of Volume 40, 1980

1354 Near Haploid Cell Line in Lymphoid Blast Crisis of 1360 Communication: A Relationship between Estrogen 1363 Announcements Ph'-positive Chronic Myeloid Leukemia. Allegria Sulfurylation and Estrogen and Progesterone Recep 1365 Errata Kessous. Pierre Colombies. Jacques Pris, and Danielle tor Status in Human Mammary Carcinoma. Thanit Clement. Pewnim, John B Adams, and Kwai P. Ho. 1366 Author Index

May, Number 5

1367 Identification Ã¶l Polysemes Synthesizing Novikoff 1486 Characteristics of Mitochondria Isolated by Rate 1630 Induction of Cytotoxic Factors by Immunization of Mice with Freund's Adjuvant Components. Reuben Hepatoma Nucleolar Antigens. John J. Remers. Jr.. Zonal Centrifugation from Normal Liver and Novikoff Frances M Davis, and Harris Busch Hepatomas. Douglas M Stocco and James C Hutson. Baumal. Alexander Marks. James Mahony. and Alaknanda Bose 1372 Pharmacological Studies Comparing the Mechanism 1493 Intracellular Concentration of Sodium and Other Ele of Tumor-induced and Activated Macropnage-in- ments as Related to Mitogenesis and Oncogenesis in 1636 in Vitro Selection of Murine B16 Melanoma Variants duced Bone Marrow Cytolysis. John F DiStefano, Vivo. I. L. Cameron, N. K. R. Smith. T. B. Pool, and with Enhanced Tissue-invasive Properties. G Poste, Gregory Beck. Rita Lysik. and Stanley Zucker. R. L Sparks J Doll. t. R Hart, and I J. Fidler 1380 Antigenic Similarity between Plasma Membrane Pro 1501 Tumor-immunotherapeutic Efficacy of Serratia mar- 1645 Cell Surface Properties of B16 Melanoma Variants teins of Fetal Hamster Cells and Simian Virus 40 cescens Polynbosomes. Richard W Urban. Bruce S with Differing Metastatic Potential. A Raz. W L Tumor Surface Antigens. W A. Weppner and i H Edwards, and William Segal McLellan, I R. Hart. C D Bucana. L C Hoyer. B-A Coggin. Jr 1506 Presence of the Rare D-Variant Heat-stable, Placen Sela. P Dragsten, and I. J. Fidler 1368 Treatment of Solid L1210 Murine Tumors with Local tal type Alkaline Phosphatase in Normal Human Tes- 1652 Immunochemical Study on the Role of Different Types Hyperthermia and Temperature-sensitive Liposomes tls. C. H. Chang. D Angellis, and William H Fishman of Microsomal Cytochrome P-45O in Mutagenesis by Containing Methotrexate. John N Weinstein. Richard Chemical Carcinogens. Kaname Kawajin, Hiromichi 1511 Orcadian Biopehodic Response of Mice Bearing Ad L MagÃn,Richard L Cysyk. and Daniel S. Zaharko Yonekawa, Nobuhiro Harada. Mitsuhide Noshiro, vanced L1210 Leukemia to Combination Therapy Tsuneo Omura. and Yusaku Tagashira 1396 Tumor-initiating Activity of Dihydrodiols Formed Met- with Adriamycin and Cyclophosphamide. Lawrence abolically from 5-MethyIchrysene. Stephen S Hecht, E Schevmg, E Robert Burns, John E. Pauly. and Franz 1658 Effect of PhÃ©nobarbitalAdministration on Hepato- Abraham Rivenson. and Dietrich Hoffmann HaIberg cytes Constituting the Hyperplastic Nodules Induced in Rat Liver by 3'-Methyl-4-dimethylaminoazoben- 1400 Different Biological Targets for Resiniferatoxin and *1516 Phase I Clinical Investigation of 1,4-Dihydroxy-5, Phorbol 12-Myristate 13-Acetate. Paul E. Dnedger and 8-bis { {{2-[(2-hydroxyethyl)amino]ethyl| amino} }- zene. Aiko Kaneko. Kimimaro Dempo, Tohru Kaku, Peter M. Blumberg. 9,10-anthracenedione Dihydrochloride (NSC Shigeaki Yokoyama. Masaaki Satoh. Michio Mori, and 301739), a New Anthracenedione. Daniel D. Von Hoff. Tamenon Onoe. 1405 Differences in Metabolism and Cytotoxicity between 9-^-D-Arabinofuranosyladenine and 9-0-o-Arabinofu* Ester Pollard, John KÃ¼hn.Edward Murray, and Charles 1663 Cell Injury by Antineoplastic Agents and Influence of ranosyl-2-fluoroadenine in Human Leukemic Lym- A. Cottman, Jr. Coenzyme Q-, on Cellular Potassium Activity and phoblasts. Lois W. Dow, Douglas E. Bell, Lawrence 1519 Active versus Passive Absorption Kinetics as the Potential Difference across the Membrane in Rat Poulakos, and Arnold Fndland Basis for Selective Protection of Normal Tissues Liver Cells. Katsuhiko Okada. Shmichi Yamada. Yasuo by S-2-<3-Aminopropylamino)ethylphosphorothioic Kawashima. Fumio Kitade, Kunio Okajima. and Mamoru * 1411 Serum Ferritin as a Guide to Therapy in Neuroblas Acid. John M. Yuhas Fu|imoto. toma. HÂ¡e-WonL Hann. Howard M. Levy, and Audrey E Evans. 1525 Enhancement of 1-^-o-Arabinofuranosylcytosine Ac 1668 Regression of Induced Keratoacanthomas in Anagen 1414 Levodopa and Dopamine Analogs as DNA Polymer- cumulation within L1210 Cells and Increased Cyto (Hair Growth Phase) Skin Grafts in Mice. Cees G toxicity following Thymidine Exposure. Steven Grant. Ramselaar, E Joost Ruitenberg. and Wim Kruizmga ase Inhibitors and Antitumor Agents in Human Mela Connie Lehman, and Ed Cadman noma. Michael M. Wick. 1674 Inhibition of Prolactin-induced Mammary Cancer in 1532 Liposomal Protection of Adriamycin-induced Cardi- C3Hf(XVIi) Mice with the frans Isomer of Bromoth- 1419 Immunohistology, Light Microscopy, and Ultrastruc otoxicity in Mice. Aquilur Rahman. Andrea Kessler. tural Morphology of Transplantable Rat Medullary phenylethylene. Michel Drosdowsky. Marc Edery. Newton More. Branimir Sikic, Geoffrey Rowden. Paul Michele Guggian. America Montes-Rendon, Georges Thyroid Carcinomas. P. J- McMillan, L. G. Thaete. Woolley. and Philip S Schein. W. M. Hooker, and B. A. Roos. Rudah. and Claude Vives 153a Modifying Role of Partial Hepatectomy and Gonad- 168O Comparison of Hepatic Cathepsin D Activity in Re 1427 Pharmacological Disposition of 1,4-Bis{2-C(2-hydrox- ectomy in Ethylnitrosourea-induced Hepatoca reino- sponse to Tumor Growth and to Caloric Restriction yethyl)amino]ethylamino} -9,10-anthracenedione Di- genesis. S. D. Vesselmovitch, L. Itze, N. Mihailovich, acetate in the Dog. Katherine Lu and Ti Li Loo. in Mice. Kent Lundholm. Lars Ekman. Ingvar Karlberg. and K. V. N. Rao. Staffan Edstrom. and Tore Schersten 1431 Mechanisms of Sensitivity and Resistance of Murine 1543 Effects of Thymidine and Thymidine plus 5-Fluorour- Tumors to 5-Fluorouracil. Bach Ardalan. David A. acil on the Growth Kinetics of a Human Lymphoid 1686 Purification of an Anemia-inducing Factor from Hu Cooney, Hiremagalur N. Jayaram. Christine K. Carneo, Cell Line. Anthony J. Murgo, Jerrold Fried. David man Placenta and Its Application to Diagnosis of Robert I. Glazer. John Macdonald, and Philip S. Schein. Burchenal, Karen L Vale, Annabel Strife. Thomas Malignant Neoplasms. Kiyota Oh-Uti, Shigeaki Inoue. Woodcock, Charles W Young, and Bayard D Clarkson and Sadamasa Minato 1438 Reexaminaron of the Role of Plasminogen Activator Production for Growth in Semisolid Agar of Neoplas- 155O Surface Labeling of Sialic Acid Residues in BHK Cells 1691 Tumor-associated Cytotoxicity of Autoantibodies in tic Hamster Cells. J. Carl Barrett. S Sheela. Kazunon and Viral Transformants. Harold Flowers and Mary Sera from Rats with Chemically Induced Hepatomas. Ohki, and Takeo Kakunaga. Catherine Glick. P Lando. F Blomberg. K Berzins. and P Perlmann 1443 Longitudinal Karyotype and Genetic Signature Anal 1558 Ultrastructural and Morphometric Study of Diethyl- ysis of Cultured Human Colon Adenocarcinoma Cell stilbestrol-associated Lesions Diagnosed as Cervical 169g Glucose Homeostasis m Rats Bearing a Transplant- Lines LS180 and LS174T. Lynne P. Rutzky, Celia I Intraepithelial Neoplasia III. W Dwayne Lawrence. able Sarcoma. Jasbir Singh. Murray R Gngor, and Kaye. Michael J. Siciliano, Margaret Chao, and Barry Hugh M. Shmgleton. Hazel Gore, and Seng-Jaw Soong. Mary P Thompson D Kahan 1568 Fetal Antigens Shared as Transplantation Rejection 1449 Turnover of 3'-Polyadenylate-containing RNA in Liv Antigens on Chemically Induced Mouse and Hamster 1707 Effects of New Antimi totic Antibiotics, Ansamitocins, ers from Aged, Partially Hepatectomized, Neonatal, Sarcomas. Joseph H Coggin, Jr.. Linda Adkmson. and on the Growth of Murine Tumors in Vivo and on the and Morris 5123C Hepatoma-bearing Rats. Robert E Norman G Anderson. Assembly of Microtubules in Vitro. Koichiro Ootsu, Moore, Tom L. Goldsworthy, and Henry C Pilot Yoshio Kozai. Masao Takeuchi. Shuichi Ikeyama, 1574 Isolation of a Cellular Subpopulation from a Human Koichi Igarashi, Kyozo Tsukamoto. Yukio Sugmo. 1456 Thioguanine-induced S and GÃ•Blocks and Their Sig Colonie Carcinoma Celt Line. Pamela M Kimball and Tazuko Tashtro, Shigeru Tsukagoshi. and Yoshio nificance to the Mechanism of Cytotoxicity. Linda L Michael G. Brattam. Sakurai. Wotnng and Joseph L Roti Roti. 1580 Time-dependent Inhibition by 2,3.7.8-Tetrachlorodi- 1463 Mutagenicity, Cytotoxicity, and DNA Binding of Plat benzo-p-dioxm of Skin Tumorigenesis with Polycyclic 1718 Mechanism of Deoxycytidine Rescue of Thymidine Toxicity in Human T-Leukemic Lymphocytes. Richard inum(ll)chloroammines in Chinese Hamster Ovary Hydrocarbons. J DiGiovanm, D L Berry. G. L. Cells. Neil P. Johnson. James D Hoeschele. Ronald O. M Fox. Edith H Tnpp. and Martin H N Tattersall Rahn, J. Patrick O'Neill, and Abraham W. Hsie. Gleason. G S. Kishore. and T J Slaga 1588 Epithelial Cell Junctions in Primary and Metastatic 1722 Effects of Estrogen and Antiestrogen on DNA Poly- 1469 Effect of Maturation on the Response of Human Pro- Mammary Tumors of Mice. Dorothy R Pitelka, Susan merase in Human Breast Cancer. Dean P Edwards. myelocytic Leukemia Cells (HL-6O)to the Tumor Pro T Narriamolo, and Barbara N. Taggart. Siva R Murthy, and William L McGuire. moter 12- O-Tetradecanoylpnorbol-13-acetate Naomi Mendelsohn. Harriet S. Gilbert, Judith K Chnstman, 1600 Basal Lamina and Tissue Recognition in Malignant 1727 Polyamine Biosynthesis Enzymes in the Induction and George Acs Mammary Tumors. Dorothy R Pitelka. Susan T Hamamoto. and Barbara N. Taggart and Inhibition of Differentiation in Friend Erythroleu- 1475 Comparative Reactivities of Esters of Oncogenic kemia Cells. Y Gaziti and C Friend and Nononcogenic Purine N-Qxides and Evidence 1612 Characteristics of Binding to Estrogen, Androgen, Progestin, and Glucocorticoid Receptors in 7,12-Oi- of the Oxidation-Reduction Reactivity of Aromatic 1733 Similarities between a Phosphoprotein (pp60vc)-as- methylbenz( a)anthracene-induced Mammary Tumors Nitrenium Ions. James C. Parham and Mary Agnes sociated Protein Kinase of Rous Sarcoma Virus and and Their Hormonal Control. Jacques Asselm, Rejean Templeton. a Cyclic Adenosine 3':5'-Monophosphate-independ- MelanÃ§on.Gilbert Moachon. and Alain BÃ©langer 1482 Pyrazofurin Inhibition of Purine Biosynthesis via 5- ent Protein Kinase That Phosphorylates Pyruvate Ki Aminoimidazole-4-carboxamide-1-/i-D-ribofuranosyl 1623 Purification and Characterization of Cytosol Protein nase Type Mj. Peter Presek, Hartmut Glossmann. 5'-Monophosphate Formyltransf erase. John F. 45/7.8 Present in Rapidly Growing Hepatomas. Katan Erich Eigenbrodt. Wilhelm Schoner. Helga Rubsamen. Worzalla and Martin J Sweeney S Raju, Harold P. Morns, and Harns Busch Robert R Frus. and Heinz Bauer

DECEMBER 1980 Contents of Volume 40, 1980

1742 Metabolie Activation oÃDibenzo( a,e)fluoranthene, a Letters to the Editor 1764 Correspondence re: S. B. Howell, R. S. Jenkins, and Nonalternant Carcinogenic Polycyclic Hydrocarbon, J. Streife!. Activity of Thymidine as a Chemothera- 1761 Potential for Inappropriate Therapeutic Application in Liver Homogenates. Odette Penn-Roussel. Martine peutic Agent against Human Tumor Xenografts in of Drug as a Result of the Use of Cell Substrates of Croisy-Delcey. Joel Mispelter. Saad Saguem. Odilon Nude Mice. Cancer Res., 39. 3875-3880,1979. S S Uncertain Derivation. Correspondence re: D. D. Chaivet. Bernard Ekert. Jacques Fouquet. Pierre Lee, B. C Giovanella. and J. S. Stehlm. Vandre. V. L. Shepherd, and R. Montgomery. Effects Jacquignon. Jean-Marc Lhoste. Bernard Muel. and Stephen B Howell Francois E Zajdela. of Macromycin on the Ultrastructure and Biological Properties of Cultured Mammalian Cells. Cancer Res-, 39: 4O91-4O97, 197g. Walter A. Nelson-Rees 1765 Correspondence re: J. K. Ball and J. A. McCarter. Communications Dale D VandrÃ©and Rex Montgomery. Biological Characterization of a Leukemogenic Virus * 175O Increase of Progesterone Receptor by Tamoxiten as 1762 Correspondence re: B. S. Wang, G. Steele, Jr., J. A. Isolated from the CFW Mouse. Cancer Res., 39: 3080-3088. 1979. Kaiman Perk a Hormonal Challenge Test in Breast Cancer. MoÃ¯se Mannick, M. FallÃ³n,and S. R. Onikul. In Vivo Effects Namer. Claude Lalanne. Etienne-Emile Baulieu. and Parallel m Vitro Cytotoxicity of Splenocytes Har vested from Treated or Control C57BL/6J Mice after 1766 Announcements 1753 Rapid, Reversible Rounding and Aggregation of Rous Adjuvant Immunotherapy of Pulmonary MÃ©tastases Sarcoma Virus-infected Chicken Fibroblasta Induced Using Xenogeneic RNA Specific to B16 Murine Mel by a Plasma Macromolecule. Samuel D Balk, Baldev anoma. Cancer Res., 39: 1702-1707, ig79. Song-yu Singh Hoon. Gillian M King. David Loskutoff, Richard Yang. S Mitchell. Dana N. LeStourgeon, and Randall J. Glenn Steele, Jr.. Bosco S. Wang, and John A. Weselake. Mannick. 1768 Author Index

June, Number 6

1769 Demonstration of Embryonic-type Hemoglobin in Ex- 1858 Humoral Modulation of Human Acute Myelogenous 1950 Inhibition of Growth of Primary and Metastatic Lewis tramedullary Hematopoietic Cells in the Liver during Leukemia Cell Growth in Vitro H Phillip Koeffler and Lung Carcinoma Cells by the Phosphodiesterase In Experimental Liver Carcinogenesis by 3'-Methyl-4-di- David W Golde hibitor Isobutylmethylxanthine. Przemyslav Jamk. methylaminoazobenzene. Katsuhiko Enomoto, Annlouise Assaf, and John S Bertram Kimimaro Dempo. Michio Mori, and Tamenon Onoe 1863 Inhibition of Mammary Tumor Growth by Dexameth- asone in Rats in the Presence of High Serum Prolactin 1955 Comparative Analyses of Cyclic Adenosine 3':5'- 1774 Differences in Colonie Nuclear Proteins of Two Levels. C F Aylsworth. P W Sylvester, F C Leung. Monophosphate Phosphodiesterases of Human Pe Mouse Strains with Different Susceptibilities to 1.2- and J Mettes. ripheral Blood Monocytes and Cultured P388D, Cells. Dimethylhydrazine-induced Carcinogenesis. Lidia C W J Thompson, C P Ross. S J Strada. E M Hersh, 1867 Postreplicatlon Repair in Three Murine Melanomas, a Botta. Bhalchandra A Diwan. Rosemarie Gruss. and and V R Lavis Vincent G AHtrey Mammary Carcinoma, and a Normal Mouse Lung Fibroblast Line. HÃ©lÃ¨neZ Hill and Richard B Setlow 1961 Effects of DL-a-Methylornithine on Proliferation and 1781 Benzo(a)pyrene Metabolism in Bovine Aortic Endo- Polyamine Content of 9L Rat Brain Tumor Cells. 1873 Glycoprotein Differences in Solid and Ascites Forms thelial and Bovine Lung Fibroblast-like Cell Cultures. Jerome Seidenfeld and Laurence J Marlon William M Baird. Ruth Chemerys, Judith B Gnnspan, of the 13762 Rat Mammary Adenocarcinoma. John Stephen N Mueller, and Elliot M Levine W Huggins. Tim P Trenbeath, Anne P Sherblom, 1967 Immunomodulatory Effect of Various Molecular- Susan C Howard, and Kermit L Carraway Weight Maleic Anhydride Divinyl Ethers and Other 1787 Purification and Properties of Hamster Liver Ligan- 1879 Comparison of the Carcinogenic Effects of Five Ni- Agents in Vivo. Michael A Chingos and William A dins, Glutathione S Transferees Garry John Smith. Stylos Virginia Sapico Ohi, and Gerald Litwack. trosamines in Guinea Pigs. Richard H Cardy and William Lijmsky 1973 Lethal and Cytokinetic Effects of Mitomycin C on 1791 Large-Capacity Separation of Malignant Cells and 1885 Allopurinol Modification of the Toxicity and Antitumor Cultured Human Colon Cancer Cells. Barthel Barlogte Lymphocytes from the Furth Mast Cell Tumor in a Activity of 5-Fluorouracil. Pauline M Schwartz. Jams and Benjamin Drewinko Reorienting Zonal Rotor. Cathy L Green, Theresa P M. Dunigan. John C Marsh, and Robert E Pretlow. Kent A Tucker. Edwin L Bradley. Jr . William 1981 Comparison of the Skin Tumor-initiating Activities of Handschumacher J Cook. Annette M Pitts, and Thomas G Pretlow II Dihydrodiols and Diol-Epoxides of Various Polycyclic *1890 Relationships of S-Phase Fraction of Breast Carci Aromatic Hydrocarbons. T J Slaga, G L Gleason. G 1797 Effect of Carcinogenic N-Alkyl-N-nitroso Compounds noma in Relapse to Duration of Remission, Estrogen Mills, L Ewald. P P Fu. H M Lee. and R G Harvey on Nicotinamide Adenine Dinucleotide Metabolism. Receptor Content, Therapeutic Responsiveness, and Myron K Jacobson. Viktorya Levi. Hector Juarez- 1985 Mutagenicity of Ben2o(e)pyrene and Triphenylene Duration of Survival. John S Meyer and Jeannette Y Salinas. Rodney A Barton, and Elaine L Jacobson Tetrahydroepoxides and Diol-Epoxides in Bacterial Lee and Mammalian Cells. Alexander E Wood, Richard L 1803 Reduction of Nicotinamide Adenine Dinucleotide Lev Chang. Mou-Tuan Huang, Wayne Levin, Roland E 1897 Early Induction of Mouse Urinary Bladder Ornithine els by Ultimate Carcinogens in Human Lymphocytes, Lehr, Subodh Kumar. Dhiren R Thakker, Haruhiko Decarboxylase Activity by Rodent Vesical Carcino Patrick W Rankin. Myron K Jacobson. Virgil R VagÃ¬,Donald M Jenna, and Allan H Conney gens. M Matsushima and George T Bryan Mitchell, and David L Busbee 1990 Activities of L-Dopa Decarboxylase and Diamine Oxi * 1902 Application of a Simple Competitive Protein-binding dase (Histaminase) in Human Lung Cancers and De 1808 Interaction of Dimethylbenzanthracene and Diethyl- Assay Technique to the Pharmacokinetics of N- carboxylase as a Marker for Small (Oat) Cell Cancer (Phosphonacetyi)-i -aspartate in Humans. Charles stilbestrol on Mammary Adenocarcinoma Formation in Cell Culture. Stephen B Baylm. Martin D Abeloft. in Female ACI Rats. Claire J Shellabarger. Barbara Erlichman, John M Strong, and Bruce A. Chabner Gregory Goodwin, Desmond N Carney, and Adi F McKnight. John Patrick Stone, and Seymour Holtzman Gazdar 1907 Comparison between the Cellular Proteins of Hairy 1812 Selection and Characterization in Culture of Mam *1995 Urinary Excretion of 3-Methoxy-4-hydroxymande)ic Cell Leukemia and the Leukemic Phase of Other Acid and 3-Methoxy-4-hydroxyphenylacetic Acid by mary Tumor Cells with Distinctive Growth Properties Lymphoproliferative Diseases. Harvey M Golomb, in Vivo. Keith G Danielson. Lawrence W Anderson. Anne H Nathans, and Glyn Dawson 288 Patients with Neuroblastoma and Related Neural and Howard L Hosick Crest Tumors. Elwood H LaBrosse, Catherine Com- 1915 Effect of Time and Duration of Exposure to 12-O- Nougue, Jean-Michel Zucker, Etienne Comoy, Claude 1820 Positive Correlation between HistolÃ³gica! Tumor In Tetradecanoylphorbol-13-acetate on X-Ray Transfor Bohuon. Jean Lemerle. and Odile Schweisguth volvement and Generation of Tumor Cell Colonies in mation of C3H 10T'u Cells. Ann R Kennedy, Gary 2002 Evaluation of Chemiluminescence Generation during Agarose in Specimens Taken Directly from Patients Murphy, and John B. Little with Small-Cell Carcinoma of the Lung. Desmond N Microsomal Metabolism of Some Carcinogens. Carney. Adi F. Gazdar. and John 0 Mmna 1921 Distribution of N-Nitrosomethylbenzylamine Evalu Godwin O Emerole and Robert L Dixon. ated by Whole-Body Radioautography and Densitom- Increased Agglutinability of Bladder Cells by Concan- *1824 Thymidine Requirements for the Rescue of Patients 2006 etry. Patricia L Kraft and Steven R Tannenbaum avalin A after Administration of Carcinogens. Tadao Treated with High-Dose Methotrexate. Stephen B 1928 Cellular Pharmacology of W.N-Dimethyl Daunorubicin Kakizoe.. Hideki Komatsu.. Tadao Nnjima. Takashi Howell. Kenneth Herbst. Gerry R Boss, and Kawachi, and Takashi Sugimura Emil Frei III and N.N-Dimethyl Adriamycin. Merrill J Egorm, Ronald E Clawson, Louis A Ross, and Nicholas R 2010 Weibel-Palade Bodies in Endothelial Cells as a 1830 Cellular Potentials of Normal and Cancerous Fibro- Bachur Marker for Angiogenesis in Brain Tumors. Pat Kumar, blasts and Hepatocytes. Richard Binggeh and Ivan L Shant Kumar, Henry B Marsden. Patrick G. Lynch, and 1934 Ultraviolet Light-induced Transformation of Human Cameron Elaine Earnshaw Cells to Anchorage-independent Growth. Betsy M 1B36 Mammary Gland Cell-mediated Mutagenesis of Mam Sutherland. Janet S. Cimino, Neva Dehhas, Alice G 2020 Glucocorticoid Receptors and in Vitro Corticosensi- malian Cells by Organ-specific Carcinogens. Michael Shih. and Rowena P Oliver tivity in Human Thymoma. Franco O Ranelletti. N Gould Stetano lacobelli, Marco Carmignani. Gigliola Sica. 1940 1-0-D-Arabinofuranosylcytosine Nucleotide Inhibition Clara Natoli, and Pietro Tonali. 1842 Partial Purification and Characterization of a Lympho cyte-inhibitory Factor(s) in Ascitic Fluids from Ovar of Sialic Acid Metabolism in WI-38 Cells. Marione W 2026 Alterations of o-Galactose Metabolism in Morris Hep- Myers-Robfogel and Ann C Spataro ian Cancer Patients. Allan D Hess. Stanley A Gall. atomas. Christian H Bauer, Reinhard Buchsei. Harold and Jeffrey R Dawson. P Morns, and Werner G. Reutter 1944 Effect of Retinole Acid on Cell Surface Glycopeptides 1852 Potent Bile Salt and Organic AniÃ³nInhibition of Meth of Cultured Spontaneously Transformed Mouse Fi- 2033 Failure of the Antioxidant Vitamin E to Protect against otrexate Uptake and Accumulation in the Freshly broblasts (BALB/c 3T12-3 Cells). Wlodzimierz Sasak. Adriamycin-induced Cardiotoxicity in the Rabbit. Isolated Rat Hepatocyte. David A Gewirtz, Joyce K Luigi M De Luca, L DavidDion, and Carol S Sitverman- Johan G S Breed. Anaen N E Zimmerman, Jan A. M. Randolph, and I David Goldman Jones A Dormans. and Herbert M Pinedo.

vin CANCER RESEARCH VOL. 40 Contents of Volume 40, 1980

2039 Nonspecific Cross-Reacting Antigen in Normal and 2054 T* and B-Cell-independent Activation of Syngeneic 2074 Specific Viral Antigens in Rat Cells Transformed by Leukemic Myeloid Cells and Serum of Leukemic Pa Macrophages by Murine Sarcoma Cells. Reidun Herpes Simplex Virus Type 2 and in Rat Tumors tients. B Wahren. G Gahrton. and S Hammarstrom Olstad. Gustav Gaudernack, Gilla Kaplan, and Roll Induced by Inoculation of Transformed Cells. Joan C Selielid M Macnab, L Visser, A T Jamieson. and J Hay 2045 Multilractionated Hyperthermia Treatment ot Malig nant and Normal Tissue in Vivo, Jens Overgaard. 2061 Selective Localization and Growth of Bifidobacterium Herman D Suit, and Alexander M Walker bifidum in Mouse Tumors following Intravenous Ad 2080 Announcements ministration. Nontaka T Kimura. Shun ichiro 2051 Increase of Antitumor Effect of Bleomycin by Re Taniguchi. Ken Aoki. and Tsuneo Baba duced Nirot inamide Adenine Dinucleotide Phosphate 2081 Errata and Microsomes in Vitro and in Vivo. Naoki Yamanaka. 2069 Age-dependent Cell Inactivation by Vincristine Alone Taketoshi Kato. Keiko Nishida, Satoru Shimizu, or in Combination with l-Propargyl-5-chloropyrimi- Masanon Fukushima. and Kazuo Ota din-2-one. Emar Wibe 2082 Author Index

July, Number 7

2083 Standardized Nomenclature tor Inbred Strains of *2223 Pharmacokinetics of 5-Fluorouracil Administered 2336 Effects of Hypothyroidism on the Induction and Mice: Seventh Listing. Joan Staats Orally, by Rapid Intravenous, and by Slow Infusion. Growth of Mammary Cancer Induced by 7.12-Dimeth- Roberto J Fraile, Laurence H Baker, Thomas R ylbenz{a)anthracene in the Rat. A David Goodman. 2129 Characterization of Immunosuppressor Cells in Rats Susan J Hoekstra, and Patricia S Marsh Immunized with Solubilized Tumor-associated Anti gens Prepared from a Methylcholanthrene-induced 2229 Effect of Subcutaneously Administered 2.6.10.14- 2343 Regulation of Estrogen-binding Capacity by Insulin in Fibrosarcoma. Akio Minami. Masaharu Kasai. Yutaka Tetramethylpentadecane on Plasmacytoma Growth. 7.12-Dimethylbenz(a)anthracene-mduced Mammary Mizushima. Nontoshi Takeichi. Masuo Hosokawa, and M Platica. C Bo|ko. G Steiner, and V P Hollander Tumors in Rats. Scott L Gibson and Russell Hilt Hiroshi Kobayashi 2234 Stabilization of 8S Progesterone Receptor from Hu 2349 Comparison of the Toxicity and Metabolism of 9-/i-n- 2135 Importance of Timing in Cyctophosphamide Therapy man Prostate in the Presence of Molybdate Ion. Arabinofuranosyl-2-fluoroadenine and 9-/J-D-Arabi- of MOPC-315 Tumor-bearing Mice. James C D Charles L Bevins and Nasir Bashirelahi noturanosyladenme in Human Lymphoblastoid Cells. Hengst. Margalit B Mokyr. and Sheldon Dray 2240 Glucocorticoid Receptors in Peripheral Blood Lym William Plunkett. Shern Chubb. Lillie Alexander, and John A Montgomery 2142 Establishment of Mouse Colonie Carcinoma Cell phocytes from Bovine Leukemia Virus-infected Cows Lines with Different Metastatic Properties. Michael G with Persistent Lymphocytosis. John C Bloom. 2356 Preferential Activation of Mitomycin C to Cytotoxic Brattam, Janna Strobel-Stevens. David Fine. Maryla Venkataseshu K Ganjam. and Thomas G Gabuzda Metabolites by Hypoxie Tumor Cells Katherine A Webb, and Awni M Sarnf 2245 Electron Microscopic Autoradiography of the Pan Kennedy. Sara Rockwell, and Alan C Sartorelli 2147 Characterization of Adenosme-induced Cytostasis in creas in the Hamster Treated with Tritiated N-Nitroso- 2361 Epidermal Growth Factor Stimulation of Human 2.6-dimethylmorpholine. Hildegard M Reznik- Melanoma Cells. John W Bynum Breast Cancer Cells in Culture. C Kent Osborne Schuller, William Lijtnsky. and Bishop F Hague. Jr Barbara Hamilton, Grace Titus, and Robert B 2153 Distribution of a Tumor Cell Surface Protein Common 2252 Indirect Rosette Microassay to Characterize Human Livingston to Several Murine Lung Carcinomas. Stephen j Melanoma-associated Antigens Recognized by Op Kennel. Patricia K Lankford. Linda J Foote. Frank S 2367 Inhibition of Skin Tumor Promotion by Retinole Acid erationally Specific Xenoantisera. Kohzoh Imai and and Its Metabolite 5.6-Expoxyretmoic Acid. Ajit K Tsakeres. Laurel M Adams, and Robert L Ullrich Soldano Ferrone Verma. Thomas J Siaga. Phillip W Wertz. Gerald C 2160 Colony Growth in Soft Agar of Human Melanoma. 2257 Adruimycin-induced Delayed Erythropoietic Injury Mueller, and R K Boutwell Sarcoma, and Lung Carcinoma Cells Disaggregated Expressed following Anemia Stress. Paul G 2372 Maintenance of MOPC 1O4E Myeloma in the Plateau by Mechanical and Enzymatic Methods. Zlatko P Braunschweiger. Larry L Schenken, and Lewis M Phase. Vithal K Chanta, Raymond N Hiramoto. Pavelic. Harry K. Slocum, Youcef M Rustum. Patrick Schiffer Dolores W Davis, and Nancy S Hiramoto J Creaven, Constanime Karakousis. and Hiroshi Takita 2263 Antitumor Activity of Monomeric and Polymeric Cy- *2377 in Vivo Effect and Parallel in Vifro Lymphocyte-me clophosphamide Derivatives Compared with in Vitro diated Tumor Cytolysis after Phase I Xenogeneic 2165 Binding to Cellular Macromolecules as a Possible Hydrolysis. Takashi Mirano. Helmut Ringsdorf, and Immune RNA Treatment of Patients with Widespread Mechanism for the Cytotoxicity of Misonidazole. A J Daniel S Zaharko Melanoma or Metastatic Renal Cell Carcinoma. Glenn Varghese and G F Whitmore Steele. Jr . Bosco Shang Wang, Jerome Richie, Richard *2268 QuantitÃ¤ten by Gas Chromatography-Chemical lom- E Wilson. Thomas Ervm, Ronald Yankee. Marguerite 2170 Microsome-mediated Covalent Binding of 1,2-Di- zation-Mass Spectrometry of Phenylalamne Mustard FallÃ³n,and John A Manmck chloroethane to Lung Microsomal Protein and in Plasma of Patients. Sharon L Pallante, Catherine Salmon Sperm DNA. Sipra Banerjee. Benjamin L Van Fenselau. Robert G Mennel, Robert B Brundrett. Mark 2383 Comparative Responses of Normal and Malignant Duuren. and Felix Ibiba Oruambo Appier. Neil B Rosenshem, and Michael Colvin Mouse Mammary Cells to Modulation ot Surface Prop erties. Bonnie B Asch. DÃ¤melMedina. Frank Kretzer. 2174 Receptor for Glucocorticoids in RPMI346O Melanoma 2273 Stimulation ot Macrophage Prostaglandin and Neu James L Connolly, and B R Brinkley Cells. Edward F Hawkins, Diane Horn, and Francis S tral Protease Production by Phorbol Esters as a Markland, Jr Model for the Induction of Vascular Changes Asso 2390 Effects of Ellipticme on Cell Survival and Cell ciated with Tumor Promotion. John A Hamilton Cycle Progression in Cultured Mammalian Cells. 2179 Changes in Growth Rate of an Experimental Solid Frank TrÃ¡ganos. Lisa Staiano-Coico, Zbigmew Tumor following Increasing Doses of Cyclophospha- 2281 Role of Organ Selectivity in the Determination of Darzynkiewicz. and Myron R Melamed mide. William B Looney. E Russell Ritenour. and Metastatic Patterns ot B16 Melanoma. Ian R Hart and Harold A Hopkins 2400 Relationship between Membrane Transport of Meth Isaiah J Fidler otrexate and Endogenous Cyclic Adenosme 3':5'- * 2184 Active Transport of Methotrexate from Cerebrospmal 2288 Sustained Release of Benzo(a)pyrene from Silicone Monophosphate in the Ehrlich Ascites Tumor, j Fluid in Humans. Udo Bode. Ian T Magrath. W Archie Polymer into the Tracheobronchial Tree of Hamsters Courtland White. Richard A Carchman, David W Fry, Bleyer. David G Poplack, and Daniel L Glaubiger and Dogs. Edwin C Shors. Paul C Fu. Kimito and I David Goldman Matsumura. Arthur H Cohen, and John R Benfield 2188 Functionality of Estrogen Receptor and Tamoxifen 2405 Neocarzinostatin-mduced DNA Strand Scission and Treatment of R3327 Dunning Rat Prostate Adenocar- 2295 Undine Kinase, Adenylate Kinase. and Guanase in Subsequent Cell Cycle Traverse m HeLa S. Cells. cinoma. Margot M Ip. Richard J Milholland. and Fred Human Lung Tumors. Olga Greengard. Jonathan F David E Berry and James M Collins Rosen Head, and Steven L Goldberg 2411 Relationship between Morphological Transformation 2194 Characterization of the Effects ot Different Retinoids 2300 Experimental Model for Quantitative Study of Metas and [3H]Thymidme Incorporation Stimulated by a on the Growth and Differentiation of a Human Mela tasis. L Ossowski and E Reich Chemical Carcinogen in Postconfluent Cultures of noma Cell Line and Selected Subclones. Frank L Hamster Embryo Cells. Stefan G D Mironescu. 2310 Loss of Malignancy during Serial Passage of Hu Meyskens, Jr and Bryan B Fuller Sheldon M Epstein, and Joseph A DiPaolo man Carcinoma in Culture and Discordance be 2197 Regional Differences in the Growth of Tumor Cells tween Malignancy and Transformation Parameters. 2417 Involvement of the lodothyronmes in Liver and Hep- Injected Intraperitoneally into Syngeneic Adult Mice. L Ossowski and E Reich atoma Cell Proliferation in the Rat. John Snort. Lawrence W Mornssey. Y A Sidky. and Robert Katherine Klein. Leonard Kibert, and Peter Ove 2316 Correlation between the Detection of Specific Mouse Auerbach Mammary Tumor Proviral Sequences and the Pres 2423 A Proposed Model for the Prediction ot Response to 2202 Synergistic Antileukemic Effect of Theophylline and ence of Pulmonary MÃ©tastasesin Mice Bearing Spon Endocrine Therapy in Breast Cancer from the Estro 1,3-Bis(2-chloroethyl}-1-nitrosourea. William D taneous Mammary Tumors. W Drohan. R D. Cardiff. gen Receptor Status of One Stte and the Number of DeWys and Sudha H Bathina J K Lund, and J Schlom Metastatic Sites. William D DeWys Joseph C Allegra, *22O9 In Vitro Effects on DNA Synthesis as a Predictor of 2323 Effect of Tumor Promoters on Ultraviolet Light-in Richard Simon, and Marc E Lippman duced Mutation and Mitotic Recombination in Sac- Biological Effect from Chemotherapy. Robert B *2428 A Prostate Antigen in Sera of Prostatic Cancer Pa Livingston. Grace A Titus, and Lance K Heilbryn charomyces cerevisiae. Bernard A Kunz, Mohammed tients. Lawrence D Papsidero, Ming C Wang, Luis A A Hannan. and R H Haynes 2213 Comparison of Properties of Mouse Cells Trans Valenzuela. Gerald P Murphy, ana T Ming Chu formed Spontaneously by Ultraviolet Light-irradiated 2330 Polyamines and Biosynthetic Enzymes in the Rat Herpes Simplex Virus or by Simian Virus 40. B Intestinal Mucosa and the Influence of Methylglyoxal- 2433 Prolactin-sttmulated Growth of Cell Cultures Estab Hampar. A L Boyd. J G Derge, M Zweig. L Eader. bis(guanylhydrazone). C W Porter. D Dworaczyk lished from Malignant Nb Rat Lymphomas. Peter W and S O Showalter. B Gams, and M M Weiser Gout. Charles T Beer, and Robert L Noble

DECEMBER 1980 ix Contents of Volume 40, 1980

2437 Evidence m Vivo and in Vitro of a Role for the Pituitary * 2512 Abnormal Responsiveness of Granulocyte-Macro- 2568 Microsomal Mixed-Function Oxidase and Activities of in the Growth of Malignant Lymphomas tn Nb Rats. phage-committed Colony-forming Cells from Patients Some Related Enzymes in Hyperplastic Nodules In Robert L Noble. Charles T Beer, and Peler W Gout with Chronic Myeloid Leukemia to Inhibition by Pros duced by Long-Term Griseofulvin Administration in taglandin E. Louis M Pelus, Hal E Broxmeyer, Bayard 2441 Effects of Tetrahydroundine on the Uptake and Me Mouse Liver. Helmut Denk. Mostafa Abdelfattah-Gad, tabolism of 1-/i-D-Arabinofuranosylcytosine (n Human D Clarkson. and Malcolm A. S Moore Romana Eckerstorfer, and Ronald E Talcott. Normal and Leukemic Cells. Oah Hsi W Ho. Carol J 2516 Relationship of Food Intake, Body Composition, and Carter. Nita S Brown. Jeane Hester. Kenneth Tumor Growth to Host Metabolism in Nongrowing 2574 Selective Inhibition by Benzaldehyde of the Uptake McCredie. Robert S Benjamin. Emil J Freireich, and Mice with Sarcoma. Kent Lundholm. Staffan Edstrom, of Nucleosides and Sugar into Simian Virus 40-transformed Cells. Masaaki Watanuki and Ken)i Sakaguchi Gerald P Bodey Ingvar Karlberg. Lars Ekman. and Tore Schersten 2523 Common Human Melanoma-associated Antigen(s) 2447 Compartmental Analysis of Linoleate and Palmitate 258O Carbohydrate Changes in Glycoproteins of a Poorly Detected by Monoclonal Antibodies. Stefan Carrel, Turnover in a Murine Carcinoma. Ramaswamy Metastasizmg Wheat Germ Agglutinin-resistant Mel Kannan. Murad Ookhtens. and Nome Baker Roberto S Accolla, Anna L Carmagnola, and Jean- anoma Clone. Jukka Finne. Tien-Wen Tao, and Max M Pierre Mach Burger 2455 Effects of Arsenic, Selenium, and Chromium on the 2529 Vasoactive Intestinal Peptide Control of Cyclic Aden- Fidelity of DNA Synthesis. Leila K TkeshelashvHi. osine 3':5'-Monophosphate Levels Â¡nSeven Human 2588 Transplantability of Human Lymphoid Cell Line, Lym- Clyde W Shearman. Richard A Zakour, R Marlene Colorectal Adenocarcinoma Cell Lines in Culture. phoma, and Leukemia in Splenectomized and/or Koplitz. and Lawrence A Loeb Marc Laburthe, Monique Roussel, Guillemette Irradiated Nude Mice. Shaw Watanabe, Yukio 2461 12-O-Tetradecanoylphorbol-13-acetate-induced Chevalier, Claudine Boissard, Christophe Dupont. Alain Shimosato. Masahito Kuroki. Yuichi Sato, and Takashi Zweibaum, and Gabriel Rosselin. Changes Â¡nSulfated Proteoglycan Synthesis in Cul Nakajima tured Chondroblasts. Maurizio Pacifici and Howard 2534 Isolation of an Inhibitor of Type II Interferon induction Holtzer from Tumor Ascitic Ffuids. Shuzo Matsubara, Midori 2596 Metabolic Activation of Mutagenic Tryptophan Pyrol- Suzukt. Masataka Nakamura. Kiyoto Edo. and Nakao ysis Products by Rat Liver Microsomes. Kenji Ishn. 2465 Effects of 12-O-Tetradecanoylphorbol-13-acetate on Ishida the Differentiation of Avian Melanocytes. Robert 2539 Inhibition of Experimental Blood-borne Lung Metas Kato Payette. Judith Biehl, Yoshiro Toyama, Sybil Holtzer, and Howard Holtzer tasis by Protease Inhibitors. Daizo Saito. Mutsuko * 26O1 Heterogeneity of the m Vitro Responses to Glucocor- Sawamura. Kazuo Umezawa, Yoshiyuki Kanai, Ghie ticoids in Acute Leukemia. F Homo. D Duval, J L 2475 Modulation of Immunological Competence in 1,2-Di- Funhata, Taijiro Matsushima, and Takashi Sugimura. Harousseau, J P Mane, and R Zittoun methylhydraztne-sensitive SWR/J Mice during Colo- 2543 Selective Toxicity of 5-S-Cysteinyldopa, a Melanin rectal Carcinogenesis. A K Szakal. B A Diwan, and Precursor, to Tumor Cells m Vitro and in Vivo Keisuke 2609 Nonrandom Chromosomal Changes in Thy-1-positive K E Blackman Fujita. Shosuke Ito, Shigeki Inoue, Yoshinobu and Thy-1-negative Lymphomas Induced by 7,12-Di- 2486 Hormonal Regulation of Cytochrome P-45O-depend- Yamamoto. Jun Takeuchi, Mikrhiro Shamoto. and methylbenzanthracene in SJL Mice. Jack Spira. ent Monooxygenase Activity and Epoxide-metaboliz- Toshiharu Nagatsu. Magda Babonits. Francis Wiener, Shmsuke Ohno. Zvi mg Enzyme Activities in Testis of Hypophysecto- 2547 Experimental Radiation Therapy and Apparent Ra- Wirschubski. Nechama Haran-Ghera. and George mized Rats. Insu P Lee. Katsushi Suzuki. Hasan dioresistance of Autochthonous Tumors Subcutane- Klein Mukhtar. and John R Bend ously Induced with 3-Methylcholanthrene in Mice. 2617 National Cancer Institute Support for Scientific Con Hiroshi Tanooka. Hiroshi Hoshmo. Kazuhiko Tanaka. 2493 Adducts from the Reaction of N-Benzoyloxy-N- ferences. John T Kalberer. Jr and Bayard H Morrison and Mizue Nagase methyl-4-aminoazobenzene with Deoxyguanosine or III 2552 Epoxide Hydrolase Activity in Native and in Mitogen- ONA in Vitro and from Hepatic DNA of Mice Treated 2623 Communication: Inability of Chinese Hamster Ovary with N-Methyl-or N.N-Dimethyl-4-aminoazobenzene. stimulated Lymphocytes of Various Human Donors. Cells to Excise O'-Alkylguanine. Regine Goth- Hansruedi Glatt. Elli Kaltenbach, and Franz Oesch W Gary Tarpley. James A Miller, and Elizabeth C Goldstein Miller :":2557 Estrogen, Androgen, Glucocorticoid, and Progester one Receptors in Progestin-induced Regression of Obituaries 2500 Cell Line Derived from a Metastasis of a Human Testicular Germ Cell Tumor. David L Bronson. Peter Human Breast Cancer. FAG Teulmgs. H A van 2625 Kanematsu Sugiura. Doms J Hul-hison Gilse. M S Henkelman. H Portengen, and J Alexieva- W Andrews. Davor Solter, Jaroslav Cervenka. Paul H 2626 V. R. Khanolkar. Lange, and Elwin E Fraley Figusch 2562 Effect of Malignant Transformation and Arginine Lim 2627 Special Announcements 2507 Insensitivtty of Chronic Myeloid Leukemia Cells to itation on Fibronectin and Other Cell Surface Macro- 2629 Announcements Inhibition of Growth by Prostaglandin E. Massimo molecules of Liver Epithelial Cultures. Manuel Rieber Aghetta. Wanda Piacibello. and Felice Gavosto and Mary S Rieber 2632 Author Index

August, Number 8

2633 Research on Esophageat Cancer in China: a Review. 27O6 Dexamethasone Regulation of Plasminogen Activator 2756 Effect of Cyclophosphamide on Mice Bearing Metti Chung S Yang. in Embryonic and Tumor-derived Human Cells. ylcholanthrene-induced Fibrosarcomas. Samuel Yu. 2645 Distribution of Non-Hodgkin's Lymphoma in the Richard Roblin and Peggy L. Young. Donald R. Lannin, Amy L Tsui-Collins, and Charles F United States between 195O and 1975. Kenneth P. 2714 Variation of Activity of Protein Kinases in Unstimu- McKhann. Cantor and Joseph F Fraumeni, Jr. lated and Phytohemagglutinin-stimulated Normal and 2762 Comparative Pharmacology of Pentamethylmelamine 2653 Enhancement by 3-lsobutyl-1-methylxanthine and Leukemic Human Lymphocytes. Ugo Carpentieri, JosÃ© and Hexamethylmelamine in Mice. Makoto Monmoto, Cholera Toxin of 12- O-Tetradecanoylphorbol-13-ace- J. Minguell. and Mary Ellen Haggard. Dianna Green. Aquilur Rahman. Abraham Goldin, and tate-stimulated Cyclic Nucleotide Levels and Orni 2719 Mutagenicity and Cytotoxicity of Various Nitrosou- Philip S Schein. thine Decarboxylase Activity in Isolated Epidermal reas in V-79 Chinese Hamster Cells. Matthews 0. Cells. Jean-Pierre Perchellet and R K. Boutwell. 2768 Quantitation of Epoxide Hydrolase Released from Bradley, Nancy A. Sharkey, Kurt W. Kohn. and Maxwell Hyperplastic Nodule and Hepatoma Microsomes. 2661 A Double-Blind Study on the Effects of Differing Pu W. Layard. Martin J. Griffin and Ken-ichi Noda. rified Cellulose and Pectin Fiber Diets on 1,2-Dimeth- 2726 Synergistic Effect of Combined Hyperthermia and a ylhydrazine-induced Rat Colonie Neoplasia. Hugh J 2774 Molecular Structures of 5,6- and 7,8-Benzoflavones, Nitrosourea in Treatment of a Murine Ependymoblas- Freeman. Gene A. Spiller. and Young S. Kim. Inhibitors of Aryl Hydrocarbon Hydroxylase. Miriam toma. Claire Ann Thuning. Nawal A Bakir. and Joel Rossi. Joseph S. Cantrell. Anthony J. Farber, Thomas 2666 Production by Lithocholic Acid of DNA Strand Breaks Warren. Dyott. H. L. Carrell, and Jenny P Glusker. in L1210 Cells. Mahmooda S. Kulkarni. Phillip M. 2730 Protection by Testosterone from Fluorouracil-in- Heidepnem. and K. Lemone Yielding. 2785 Ability of Dietary Fat to Overcome the Resistance of duced Toxicity without Loss of Anticancer Activity 2670 Effect of Dietary Selenium on the Interaction between Mature Female Rats to 7,12-Dimethylbenz(a)anthra- against Autochthonous Murine Breast Tumors. cene-induced Mammary Tumorigenesis. Clement Ip 2-Acetylaminofluorene and Rat Liver DNA in Vivo. Robert L. Stolti. Robert C. Sawyer. Rabmdranath Mitchell S. Wortzman. Howard J. Besbris, and Arthur Nayak. Sol Spiegelman. and Daniel S. Martin. 2790 Association of Host Immunity with 5-Fluorouracil-ini- M Cohen. tiated Cure of Plasmacytoma LPC-1 in BALB/c Mice. 2736 Human Fibroblast Strain with Normal Survival but Morris N Teller and Ronald B Faanes. 2677 Influence of Differentiation and Cell Kinetics on the Abnormal Postreplication Repair after Ultraviolet Susceptibility of the Rat Mammary Gland to Carci Light Irradiation. Jay Doniger. Susanna F Barrett, and 2796 Inhibition of Chemically Induced Morphological nogenesis. Jose Russo and Irma H. Russo Jay H Robbins. Transformation and Reversion of the Transformed 2688 Phagocytosis of Nickel Subsulfide Particles during 2740 In Vivo Metabolism and Whole-Blood Clearance of N- Phenotype by Ascorbic Acid in C3H/10T'/Â¡ Cells. the Early Stages of Neoplastic Transformation in Nitrosomethylbenzylamine in the Rat. Patricia L Kraft. William F, Benedict, William L Wheatley. and Peter A Tissue Culture. Max Costa and Hilton H Mollenhauer. Paul L. Skipper, and Steven R. Tannenbaum. Jones. 2695 Comparative Effects of Vindesine, Vinblastine, and 2743 Cloning of Human Ovarian Cancer Cells in Soft Agar 2802 Influence of Dietary Lipotrope and Lipid Content on Vincristine on Mitotic Arrest and Hormonal Response from Malignant Effusions and Peritoneal Washings. Aflatoxin B,. rV-2 Fluorenylacetamide. and 1,2 Di of L1210 Leukemia Cells. Sandra M H Howard. Robert F. Ozols. James K. V Willson. Karen R. methyl hydrazine Carcinogenesis in Rats. Adnanne E Athanasios Theologides. and J R Sheppard. Grotzmger. and Robert C. Young. Rogers. Gregory Lenhart. and Gayle Morrison. 2701 Mechanism of 5-Azacytidine-induced Transfer RNA 2748 Modulation of the Cytotoxic Response against Allo- 2808 Binding of Monosialoganglioside by Murine Thymus Cytosine-5-methyltransferase Deficiency. Lee-Jane geneic Tumor Cells in Culture by Adriamycin. Vesna Cells in Vitro. Rajabather Krishnaraj, Yeheskel A. Saat, W Lu and Kurt Randerath. Tomazic. M. Jane Ehrke. and E. Mihich. and Robert G Kemp.

CANCER RESEARCH VOL. 40 Contents of Volume 40, 1980

2814 Activation of Ftorafur [ff,S-1-{Tetrahydfo-2-furanyl)- 2876 Mutagenicity of the Dihydrodiols and Bay-Region 2925 Carcinogenic Effect of Dinitrosopiperazine in Adult 5-fluorouracil] to 5-Fluorouracil and y-Butyrolactone. Diol-Epoxides of Benzo{c)phenanthrene in Bacterial Swiss Mice and after Transplacental or Translacta- J Lai-Sim Au and Wolfgang SadÃ©e and Mammalian Cells. Alexander W Wood. Richard L tional Exposure. M Borzsonyi. G Torok. A Pinter, A Chang. Wayne Levin. Dene E. Ryan. Paul E. Thomas. Surjan. L Nadasdi, and P Roller 2820 Inhibitory Effects of Phenolic Compounds on Martine Croisy-Delcey. Yitzhak Itlah, Haruhiko Yagi, Benzo(a)pyrene-induced Neoplasia. Lee W. Donald M Jerma, and Allan H Conney 2928 Specific Immunodiagnosis of Hepatoma by Tube Leu Wattenberg. Judith B Coccia, and Luke K T. Lam. 2884 Cyclic Adenosine 3':5'-Monophosphate-binding Pro kocyte Adherence Inhibition Assay and a Modified 2824 Short Time Interval Effects of Butylated Hydroxyani- tein, a Biochemical Marker of Neuroblastoma Differ Method ot Repeated Tube Leukocyte Adherence In sole on the Metabolism of Benzo(a)pyrene. Luke K. entiation. Nagmdra Prashad. Roger Rosenberg. Fred hibition Assay. Toshio Monzane. Naoki Kumagai. Kanji T Lam. Alan V Fladmoe, J Bradley Hochalter, and Lee Baskin. Dennis Sparkman. Carlene Ulrich, and Betsy Tsuchimoto. Tetsu Watanabe. and Masaharu Tsuchiya W Wattenberg. Wischmeyer Communications 2829 Effects of Different Shortwave Radiofrequencies on 289O Cryopreservation of Cells for Immunological Typing Tumor Growth. Stephen P Auda, Chatchaval of Non-Hodgkin's Lymphomas. Adn A Bom-van 2935 Inhibition of Intercellular Communication by Tumor- Vuthiganon. and E. George Elias. Noorloos. Agaath A M. van Beek. and C J M Mehef promoting Phorbol Esters. D James Fitzgerald and 2835 Effect of Dose Fractionation of Daunorubicin on Sur 2895 Changes in Patterns of S-Adenosylmethionine Syn- Andrew W Murray vival of Leukemic Cells. Aly Razek. Fred Valenote. and thetases in Fetal and Postnatal Rat Liver. Gensaku Teresa Vietti Okada, Yoshio Watanabe, and Kinji Tsukada 2938 Serum Undine Levels in Patients Receiving N-{Phos- phonacetylK-aspartate. Jean M Karle. Lawrence W 2839 Benzidine Binding to Nucleic Acids Mediated by the 2898 Autoradiographic Demonstration of DNA Repair Syn Anderson, Charles Erlichman. and Richard L. Cysyk. Peroxidative Activity of Prostaglandin Endoperoxide thesis in Rat Trachea! Epithelium Treated with Chem Synthetase. Terry V Zenser. Michael B Mattammal, ical Carcinogens in Vitro. Takatoshi Ishikawa. Shozo 2941 Letter to the Editor: Effect of Chemotherapeutic Harvey J Armbrecht, and Bernard B Davis Takayama. and Fumio Ide. Agents on the Formation of Estrogen-Receptor Com 2846 Biological and Cell Kinetic Properties of a Human 29O4 Effect of Formation and Removal of Aflatoxin B,:DNA plex in Human Breast Tumor Cytosol. R Enzio Muller. Colonie Adenocarcinoma (LoVo) Grown in Athymic Adducts in 10TVz Mouse Embryo Fibroblasts on Cell Beth E Sheard. Abdulmaged Traish, and Herbert H Mice. James J. Stragand. Jean-Pierre Bergerat. R Viability. Tzu-chien V Wang and Peter A. Cerutti Wotiz. Allan White. James Hokanson. and Benjamin Drewmko 2910 Reduction of Epoxy Derivatives of Benzol a)pyrene by 2853 Identification and Partial Characterization of the Ma 2943 Meeting Report: Third Annual Interdisciplinary Can Microsomal C ytoc h rome P-45O. Masahiko Sugiura, jor Galactoproteins Present at the Surface of AS-30D cer Research Workshop. Peter Politzer. leva R Yasushi Yamazoe. Tetsuya Kamataki. and Ryuichi Hepatocellular Carcinoma Cells. John R Glenney. Jr., Pulitzer, and Paul G Seybold. Kato Phyllis J. Kaulfus. Bradley W. Mclntvre. and Earl F 2945 Special Announcements Walborg. Jr. 2915 DNA Single-Strand Breaks and Sister Chromatid Ex 2947 Announcements 2860 Defective Cyclic Adenosine 3':5'-Monophosphate-de- changes Induced by Treatment with Hematopor- phyrm and Light or by X-Rays in Human NHIK 3025 pendent Phosphorylation of Plasma Membrane Pro 2948 Errata teins in Chemically and Virally Transformed Cells. Cells. Johan Moan, Helga Waksvtk. and Terje Chnstensen. Robert E Scott and Thomas P. Dousa. 2949 Recent Deaths 2919 Stimulation by Interferon of Induction of Differentia 2869 Phase and Cell Cycle Specificity of Pyrazofurin Ac 2950 Books Received tion. Edith Olah. May S. Lui. Diana Y Tzeng, and tion of Mouse Myeloid Leukemic Cells. Mikio Tomida. George Weber Yun Yamamoto. and Motoo Hozumi 2952 Author Index

August, Number 8, Part II

PROGRAM PLANNING COMMITTEE

Chairman David M. Goldenberg

Committee Members Frank H. DeLand K. Robert Mclntire

PROGRAM

SESSION I Radiolabeled Antibodies and Tumor Markers

Chairperson: David Pressman

An Introduction to the Radioimmunodetection of Cancer David M Goldenberg 2957 The Development and Use ot Radiolabeled Antitumor Antibodies David Pressman 2960 Factors Influencing Localization of Labeled Antibodies in Tumors William F. Bate, M. Angeles Contreras, and Edgar D Grady 2965 Historical Development and Potential Uses of Tumor Antigens as Markers of Human Cancer Growth Phil Gold and Joseph Shuster 2973 Diagnostic Significance of Tumor Markers Sabine U von Kleist 2977

SESSION II

Carcinoembryonic Antigen and a-Fetoprotein Radioimmunodetection

Chairperson: K. Robert Mclntire

Immunological Considerations in the Use of Goat Antibodies to Carcinoembryonic Antigen for the Radioimmunodetection of Cancer F. James Primus and David M. Goldenberg 2979 Radioimmunodetection of Cancer with Radioactive Antibodies to Carcinoembryonic Antigen David M. Goldenberg. E Edmund Kim. Frank H DeLand. Sidney Bennett, and F. James Primus 2964 Radioimmunodetection of Gastrointestinal Neoplasms with Antibodies to Carcinoembryonic Antigen K. R. HiÃ±e. A R. Bradwell. T. A. Reeder. Z. Drolc, and P W. Dykes 2993 Lymphoscintigraphy with Radionuclide-labeled Antibodies to Carcinoembryonic Antigen Frank H. DeLand, E. Edmund Kim, and David M Goldenberg 2997 Use of Isotopie Immunoglobuhn in Therapy S E. Order, J. L Klein. D. Ettmger. P. Alderson, S. Siegelman. and P Leichner 3001 Radioimmunodetection of Cancer with Radiolabeled Antibodies to o-Fetoprotem E Edmund Kim. Frank H. DeLand. M Owens Nelson. Sidney Bennett, Guy Simmons. Elliot Alpert. and David M Goldenberg 3008

DECEMBER 1980 xi Contents of Volume 40, 1980

Localization of Radioiodinated Antibody to a-Fetoprotein in Hepatoma Transplanted in Rats and a Case Report of o- Fetoprotein Antibody Treatment of a Hepatoma Patient 7".Ko//, N. Ishii. T Munehisa. Y Kusumoto, S. Nakamura. A. Tamentsht.A HarÃ¡.K Kobayasht, Y Tsukada. S Nishi. and H Hirai 3013

SESSION III Other Markers for Radioimmunodetection

Chairperson: Kenneth D. Bagshawe Preliminary Therapeutic and Localization Studies with Human Chononic Gonadotrophin K. D. Bagshawe, F Searle, J. Lewis. P Brown, and P. Keep 3016 Localization of 13'l-labeled Antibodies in Human Renal Cell Carcinomas and m a Mouse Hepatoma and Correlation with Tumor Detection by Photoscanning T Ghose, S. T Norvelt, J Aquino, P. Belitsky. J. Tai, A. Guclu. and A. H. Blair 3018 Isolation of Prostatic Acid Phosphatase-binding Immunoglobulm G from Human Sera and Its Potential for Use as a Tumor-localizing Reagent Lawrence D Papsidero. John W. WoÂ¡c>eszyn.Julius S. Horoszewicz, Susan S. Leong. Gerald P Murphy, and T Ming Chu 3032

SESSION IV

Radiolabeling

Chairperson: William C. Eckelman

Radiolabeiing of Antibodies William C. Eckelman, Chang H. Paik. and Richard C fÃeba 3036 Radiolabeling of Affinity-purified Goat Anti-Carcinoembryonic Antigen Immunoglobulin G with Technetium-99m William A- Pettit. Frank H. DeLand. Sidney J. Bennett, and David M. Goldenberg 3043

SESSION V

Imaging in Radioimmunodetection

Chairperson: Frank H. DeLand

Imaging Approach in Radioimmunodetection Frank H DeLand. E. Edmund Kim, Guy Simmons, and David M Goldenberg 3046 Imaging Techniques for the Radioimmunodetection of Cancer F David Rollo and James A. Patton 3050 Theoretical Limitations in the Immunodiagnostic Imaging of Cancer with Computed Tomography and Nuclear Scanning S David Rockoff. David J. Goodenough. and K Robert Mclntire 3054

SESSION VI

Other Detection Methods

Chairperson: Peter J. Ell

Radioisotope Section Scanning P. J EÃŒIand O. Khan 3059 Radiocolloid Lymphoscintigraphy in Neoplastic Disease Gunes N. Ege 3065 Ultrasound as a Useful Imaging Modality for Tumor Detection and Staging Carol A Mittetstaedt 3072 Potential Pathological Application of Immunocytochemical Methods to the Detection of Micrometastases J. P. Sloane, M. G. Ormerod, ano A. M. Neville 3079

SESSION VII

Summation and Perspectives

Chairperson: Norman Zamcheck

Tumor Markers tor Radioimmunodetection of Cancer K. Robert Mclntire 3083 Concluding Remarks Norman Zamcheck and Glenn Steele, Jr. 3086

September, Number 9

3O89 Effects of Retinoic Acid on Plasminogen Activator 3112 Ultrastructure of the Hormone-dependent N-Nitroso- 3141 Structure-Activity Relationships among Various Reti and Mitogenic Responses of Cultured Mouse Celts. methylurea-induced Mammary Carcinoma of the Rat. noids and Their Ability to Inhibit Neoplastic Transfor Edward W. Schroder. lih-Nan Chou, and Paul H Black Michael T Tseng mation and to Increase Cell Adhesion in the C3H IGT'Â»CL8 Cell Line. John S Bertram. 3095 Synergistic Effect of Chronic Prolactin Suppression 3116 Methylated Purines in Human Liver DNA after Proba and Retinoid Treatment in the Prophylaxis of N- ble Dimethylnitrosamine Poisoning. Deborah C Methyt-N-nitrosourea-induced Mammary Tumorigen- *3147 Serotherapy of a Patient with a Monoclonal Antibody HerrÃ³nand Ronald C Shank. esis in Female Sprague-Dawley Rats. Clifford W Directed against a Human Lymphoma-associated An Welsch. Carolyn K Brown. Margaret Goodnch-Smith. 3118 Variations in Cell Form and Cytoskeleton in Human tigen. Lee M Nadler. Philip Stashenko. Russell Hardy, Jane Chiusane, and Richard C Moon Breast Carcinoma Cells in Vitro. B R Brmkley. P T. William D. Kaplan, Lawrence N Button. Donald W Beali. L. J. Wible. M. L. Mace. Donna S. Turner, and R Kufe, Karen H. Antman. and Stuart F. Schlossman 3099 Enhancement of Naturally Occurring Human Sponta neous Monocyte mediated Cytotoxicity by c/s-Diam M. Cailleau minedichloroplatinumfll). Eugenie S. Klemerman, 3130 New Experimental Model of Meningea! Leukemia. 3155 Use of Unscheduled DNA Synthesis in Freshly Iso Leonard A. Zwelling, and Andrew V. Muchmore. Raymond D A. Peterson, John N Varakis. and L Bryan lated Human Intestinal Mucosa! Cells for Carcinogen Cheshire 3103 Correlation of Serum, Tumor, and Liver Serum Gly Detection. Hugh J Freeman and Richard H C San coprotein:N-Acetylneuraminic Acid Transferase Ac * 3134 Radiosensitive. Thymic Hormone-sensitive Peripheral tivity with Growth of the R3230AC Mammary Tumor Blood Suppressor Cell Activity in Cancer Patients. 3158 Comparative Effects of Estrogen and Antiestrogen in Rats and Relationship of the Serum Activity to Evan M. Hersh, Yehuda Z Patt, Samuel G Murphy, on Enzyme Activities in R323OAC Rat Mammary Tu Tumor Burden. Irene M Evans. Russell Hilf. Michael Karel Dicke. Axe! Zander, Marvette Adegbite. and Ruth mors and Uteri of Tumor-bearing Animals. Ellen A Murphy, and H. Bruce Bosmann. Goldman. Rorke and Benita S. Katzenellenbogen

xii CANCER RESEARCH VOL. 40 Contents of Volume 40, 1980

3351 Disposition of the Carcinostatic Agent H2-Cloro- *3163 Penetration of N -{Phosphonacety IK -espÃ¡rtate into 3252 Immunoiogical Properties ot Malignant and Nonma- ethyl)-3-[1'-(5'-p-nitrobenzoyl-2'.3'-isopropylidene>- Human Central Nervous System and Intracerebral lignant Sublines of L-Cells. Vadim A Lavrovsky and a,/i-D-riboturanosyl}-1-nitrosourea in Animals. Denise Tumor. David J Stewart. Milam Leavens. Jacqueline Victor K. Viksler. Godeneche. Jean-Claude Madelmont, Mane-France Friedman, Robert S BenjamÃn. E Colleen Moore. 3259 Use of Primary Cultures of Adult Rat Hepatocytes on Moreau. Daniele Montoloy. and Robert Plagne Gerald P Bodey. Manuel Valdivieso. Michael A Collagen Gel-Nylon Mesh to Evaluate Carcinogen-in Burgess, Charles Wiseman, and Ti Li Loo duced Unscheduled DNA Synthesis. Alphonse E *3357 Relationship of Presence ot Progesterone Receptors 3167 Production of Prostaglandin E? by Tumor Cells in Sirica. Chiou G. Hwang. Gerald L Sattler, and Henry to Prognosis in Early Breast Cancer. Mane-France Vitro. Kim Owen. Diana Gomolka. and Michael J C Pitot PichÃ³n. Claude Pallud. Maurice Brunei, and Edwin Milgrom Droller 3268 Effects of Varying the Dietary Concentration of PhÃ© 3172 Purification of Estrogen Receptors from MCF-7 Hu nobarbital on Its Enhancement of 2-Acetylaminoflu- 3361 Cytoplasmic Estrogen Receptor in a Pregnancy-de man Breast Cancer Cells. Ming Ta Chong and Marc ort;ne induced Hepatic Tumorigenesis. Carl Peraino. pendent Mouse Mammary Tumor (TPDMT-4) and Re Lippman Everett F. Staffeldt, David A Haugen, Louise S lated Autonomous Lines. Akio Matsuzawa. Yukiko Lombard. Fred J Stevens, and R. J Michael Fry Mizuno, Tadashi Yamamoto, Takashi Hon. and Teluro 3177 Increase in Cellular RNA in Cells Infected with DNA Oncogenic Viruses. Salvatore Petralia. Kenneth J 3274 Esters of Chiorohydroxyacetone in Chemotherapy of Suzuki Soprano. Sharon Pochron, Zbigmew Darzynkiewicz Murine Tumors. Paula Babiarz-Tracy. Dennis 3369 Enhancement ot Viral Gene Expression in Friend Er- McCarthy. Paul Simon, William J Burlmgham. and Frank TrÃ¡ganos, and Renato Baserga ythroleukemic Cells by 12-O-Tetradecanoylphorbol- Thomas P Fondy 3181 Pyrimidine Dimer Formation and Repair in Human 13-acetate. Giulia Colletta. Pier Paolo Di Fiore. Maria Skin. Betsy M Sutherland, Leonard C Harber. and 3281 Elevation ot Lysosomal Enzymes in Primary Lewis Ferrentino, Concetta Pietropaolo, Mana Caterina Irene E Kochevar Lung Tumor Correlated with the Initiation of Metas Turco, and Giancarlo Vecchio tasis. Lajos Dobrossy, Zlatko P Pavelic, Mary 3186 DNA Damage in Rat 9L Cells Treated with Nitrogen Vaughan. Nancy Porter, and Ralph J Bernacki 3374 Intervening DNA Insertions and the Alteration of Gene Mustard and 1,3-Bis(2-chloroethyl}-1-nitrosourea As Expression by Carcinogens. Myrtle J Fahmy and O sayed by Viscoelastometry and Si Nuclease. Richard 3286 Increased Activation of 1-^-o-Arabinofuranosylcyto- G Fahmy H Shafer and Eric S. Chase sine by Hydroxyurea in L1210 Cells. Carol T Walsh. Ruth W Craig, and Ram P Agarwal 3194 Identification and Partial Purification of Human Tu 3383 Sensitivity of Leukemic Human Null Lymphocytes to mor Nucleolar Antigen 54/6.3. Put-Kwong Chan. * 3293 Cerebrospinal Fluid Polyamines in Patients with Glio- Deoxynucleosides. Richard M Fox. Edith H Tripp. Angela Feyerabend. Rose K Busch, and Harris Busch blastoma Multiforme and Anaplastic Astrocytoma. Sylvia K. Piddington. and Martin H N Tattersall Dorcas S Fulton, Victor A Levin, Warren P Lubich. 32O2 Effect of Feeder Cell-released Substances on the Charles B Wilson, and Laurence J Marton 3387 Expression of a Cell Surface Glycoprotein (p18O) Survival of Clonogenic 91 Cells after Treatment with Related to Cell-Substratum Adhesion during Differ Antimetabolites. Michael Weizsaecker and Dennis F 3297 Metabolism of Benzo(a)pyrene by the Isolated Per entiation ot Mouse Myeloid Leukemia Cells. Kenji Deen fused Rat Testis. l P Lee and J Nagayama Sugiyama. Mikio Tomida. Yoshio Honma. and Motoo 3206 L-Ethionine as an Inducer ot Differentiation in Human *33O4 Phase I and II Trial of 4 -(9-Acndmylammo) Hozumi Promyeiocytic Leukemia Cells (Ht. 60). Naomi methanesulfon-m-anisidide in Patients with Acute 3392 Coincidental Development ot Forestomach Papilloma Mendelsohn, Josef Michl. Harnet S Gilbert. George Leukemia. Zalmen A Arlin, Robert B Sklarorf. Timothy and Prepyloric Ulcer in Nontreated Mutant Mice of Acs, and Judith K. Chnstman S Gee, Sanford J Kempin. Jane Howard. Bayard D W/W and SÃ/Si" Genotypes. Yukiniko Kitamura. 3211 Immunotherapy ot the Guinea Pig Line 10 Hepatocar- Clarkson. and Charles W Young. Masao Yokoyama. Hiroshi Matsuda, and Masanon cinoma with a Variety of Nonviable Bacteria. Michael 3307 Suppression of Lectin-stimulated DNA Synthesis in Shimada J Brunda. Herbert L Mathews, H Rodney Ferguson, Bovine Lymphocytes by the Tumor Promoter 12-O- 3398 Communication: Induction of Squamous Cell Carci J Kenneth McClatchy. and Percy Minden Tetradecanoylphorbol-13-acetate. Andrea M. Mastro nomas ot the Rat Nasal Cavity by Inhalation Exposure and Karen G PÃ©pin. 3214 Suppression and Immunotherapy of the Guinea Pig to Formaldehyde Vapor. James A Swenberg, William Line 10 Hepatocarcinoma Mediated by Heat-killed D Kerns, Ralph I Mitchell, Edward J Gralla. and Disrupted Mycobacfenum bows Strain Bacillus Cal- 3313 Interaction of cis-Diamminedichloroplatinum (II) with PM-2 DNA. Seymour Mong. Cheng H. Huang. Archie Kenneth L. Pavkov mette-GuÃ©r/n. Percy Minden and Herbert L Mathews W Prestayko. and Stanley T. Crooke. 3218 Cloning ot Human Lymphocytes Reactive with Autol- Letters to the Editor ogous Leukemia Cells. Gyorgy Csako. Richard A 3318 Effects of Second-Generation Platinum Analogs on Binder. Arthur N. Kales, and John R Neete Isolated PM-2 DNA and Their Cytotoxicity m Vitro and 3403 Correspondence re: E. H. Perkins and L. H. Cacheiro. in Vivo. Seymour Mong. Cheng H Huang. Archie W Immunodepression, a Noncontributor to Radiation- 3222 Destruction of Extracellular Matrices Containing Gly- Prestayko, and Stanley T Crooke induced Leukemogenesis of the RFM Mouse. Cancer coprotems. Elastin, and Collagen by Metastatic Hu Res.. 40: 357-361. 1980. John M Yuhas man Tumor Cells. Peter A Jones and Yves A 3325 Carcinogenicity of 3-Chloronitrosopiperidine, 4-Chlo- E H Perkins DeClerck ronitroBOpiperidine, and 3,4-Dichloronitrosopiperi- dine in Fischer Rats. W Lijinsky. J. E Saavedra, M D 3228 Effect of Ascorbic Acid on the Resistance of the 3405 The Search for Viruses as Etiological Agents in Leu Reuber. and B. N. Blackwell Extracellular Matrix to Hydrolysis by Tumor Cells. kemia and Malignant Lymphomas: The Role ot the Yves A DeClerck and Peter A Jones Happy Accident and the Prepared Mind. Ludwik 3328 Repair of Cell Killing and Neoplastic Transformation Gross. 3232 Characterization ot Estradici. Progesterone, and Pro at Reduced Dose Rates of *Â°Co y-RayÂ» Antun Han. lactin Receptors in N itrosomethy Iurea-induced Mam Colin K. Hill, and M M Elkind. mary Tumors and Effect of Antiestrogen Treatment 3408 Correspondence re: M. J. Siciliano. M. E. Bordeion on the Development and Growth of These Tumors. 3333 Metabolism and Biological Activity of 5'-Deoxy-5- Riser, R. S. Freedman, and Peter O. Kohler. A Human Trophoblastic Isozyme (LÃ¡clate Dehydrogenase-Z) Lucile Turcot-Lemay and Paul A Kelly Fluorouridine, a Novel Fluoropyrimidine. R Douglas Armstrong and Robert 8 Diasio. Associated with Choriocarcinoma. Cancer Res.. 40: 3241 A New Assay for the Microsomal Metabolism of Ni- 283-287. 198O. MichaelJ Siciliano trosamines. James G Farrelly 3339 Behavior of Inosine Phosphorylase (EC 2.4.2.1 ) Activ 3245 Failure of the Phorbol Ester 12-O-Tetradecanoylphor- ity in Normal, Differentiating, and Regenerating Liver 3409 Special Announcements bol-13-acetate to Enhance Sister Chromatid Ex and in Hepatomas. Harutoshi Kizaki. Harold P Morns, and George Weber change, Mitotic Segregation, or Expression of Muta 3411 Announcements tions In Chinese Hamster Cells. Larry H Thompson. Raymond M Baker. Anthony V Carrano. and Kerry W 3345 Stimulation of Melanogenesis in a Human Melanoma Cell Line by Retinoids. Reuben Lotan and Dalna Lotan 3412 Author Index Brookman

October, Number 10

3443 Differentiation and DNA Synthesis in Pancreatic Aci- 3468 Quercetm. a Rat Intestinal and Bladder Carcinogen 3413 Structure-Activity Relationships ol Retinoids in Ham Present in Bracken Fern ( Pteridium aqutlinum). A ster Trachea! Organ Culture. Dianne L Newton, nar Carcinoma of Rat. Janardan K Reddy, M Sambasiva Rao, John R Warren. Saeed A. Qureshi. Mahir Pamukcu. Senay Yaicmer. James F Hatcher. William R Henderson, and Michael B Sporn and Erik I Chnstensen and George T Bryan *3426 Chromosome Markers and Evidence for Clone For 3473 Formulation and Biological Distribution of Radiola- mation in Lymphocytes of a Patient with Sezary Syn 3455 Eftect of Bacillus Calmette-Guerm on the Develop beled 1-(2-Chloroethyl}-3-cyclohexyl-1-nitrosourea in drome. Jan C Liang, Mary Esther Gaulden. and James ment of Primary Lung Cancer in Syrian Golden Ham an Animal Tumor Model. Frank P Castronovo, Jr.. H Herndon. Jr sters. Bruce S Zwilling and Gary W Davis Ma|ic S Potsaid. and Susan Kopiwoda * 3430 Increased Gastrointestinal Absorption ol Large Mol 3459 Setective Killing of Glucose and Oxygen-deprived 3477 Tumor-specific Suppressor Cells Induced by Immu ecules Â¡nPatients Â«ifter 5-Fluorouracil Therapy for HeLa Cells by Hyperthermia. Sang Hie Kim, Jae Ho nization with Spleen Cells from Tumor-bearing Ani Met a? tiit it: Colon Carcinoma. George R Siber Robert Kim. Eric W Hahn, and Neale A Ensign mals. Sally A Huber, Giuseppi Bigi, and Zoltan J J Mayer, and Myron J Levin 3463 Mutagenic Activities ot Oxidized Derivatives ot N- Lucas Nitrosodipropylamine in the Liver Cell-mediated and 3437 Lethality of Nogalamycm. Nogalamycin Analogs, and 3484 Cycling ot Immune Responses to a Syngeneic Murine Adriamycin to Cells in Different Cell Cycle Phases. Salmonella typhimurium Assays. Robert Langenbach. Mammary Adenocarcinoma. Sally A Huber, Giuseppi Bi]oy K Bhuyan, Constance L Blowers, and Kathleen Ralph Gingell, Charles Kuszynski. Betty Walker. Donald Bigi, and Zoltan J Lucas D Shugars Nagel, and Parviz Pour

DECEMBER 1980 xiii Contents of Volume 40, 1980

3491 Comparative Analysis of the Immunosuppressive 3610 Metabolism and Chemotherapeutic Activity of 9-/ÃŒ-D- 3723 Effects of W, W-Bis(2-chloroethyl)-n/-nitrosourea and Properties of Two Antiviral, lodinated Thymidine An Arabinofuranosyl-2-fluoroadenine against Murine 2-[3-(2-Chloroethyl)-3-nitrosoureido)-2-deoxy-o-glu- alogs, 5-lodo-2'-deoxyuridine and 5-lodo-5'-amino- Leukemia L1210 and Evidence for Its Phosphoryla- copyranose upon the Proliferation. DNA Synthesis, 2'.5'-dideoxyuridine. June Kan-Mitchell. Malcolm S tion by Deoxycytidine Kinase. R W Brockman, Yung- and Viability of Cultured Sensitive and Resistant Mitchell. Tai-Shun Lin. and William H Prusoff Chi Cheng, Frank M Schabel. Jr. and John A. L1210 Cells. Glynn P Wheeler. Jo Ann Alexander, and Montgomery. Dons J Adamson 3495 Inherent Changes in the in Vivo Growth Characteris tics of C3H He Mammary Carcinomas. Jan Vaage 3616 Quantitative Evaluation of the Promotion by 2,3,7.8- 3728 Comparison of Polypeptide Profiles in Normal and Transformed Kidney Cell Lines Derived from Control. 35O2 Establishment of Continuous, Clonable Cultures of Tetrachlorodibenzo-p-dioxin of Hepatocarcinogene- Dimethylnitrosamine-treated. and Renal Tumor-bear Small-Cell Carcinoma of the Lung Which Have Amine sis from Diethylnitrosamine. Henry C Pitot. Thomas ing Rats, with Particular Reference to Contractile Precursor Uptake and Decarboxylation Cell Proper Goldsworthy. H. A Campbell, and Alan Poland. ties. Adi F Gazdar. Desmond N Carney. Edward K Proteins. Gordon C Hard. F M Clarke, and B H Toh 3621 Assessment of Bleomycm Lung Toxicity Using Angio- Russell. Harvie L Sims. Stephen B Baylin. Paul A tensin-converting Enzyme in Pulmonary Lavage. 3735 Synergistic Effect of Adriamycin and Ricm on L 1210 Bunn, Jr , John G Guccion. and John D Minna. Leukemic Cells in Mice. Oystem Fodstad Rober! A Newman, Pnscilia J Kimberly. James A and Alexander Pihl 3508 Genetic Factors in Escherichia coli That Affect Cell Stewart, and Jason Ketley Killing and Mutagenesis Induced by Benzo{ a)pyrene- 3740 in Vitro Studies on Selective Inhibition of Tumor Cell 7.8-dihydrodiol 9.10-Oxide. Vesna Ivanovic and I 3627 Circulating Immune Complexes in Sera of Dogs with Growth by Seminal Ribonuclease. Stefania Vescia. Bernard Weinstein Benign and Malignant Breast Disease. Bruce R Donatella Tramontano, Gabnella Augusti-Tocco, and Gordon. Scott Moron", Arthur I Hurvitz, Robert E Giuseppe D Alessio 3512 In Vitro Release of Biologically Active Adriamycin by Malus. E. Gregory MacEwen. Robert A Good, and Magnetically Responsive Albumin Microspheres. Noorbibi K Day 3745 Strain- and Sex-linked Effects of Dietary Potyunsat- Kenneth J Widder. Andrew E Senyei, and David F urated Fatty Acids on Tumor Growth and Immune Ranney 3632 Diminished Hepatic Binding Protein for Desialylated Functions in Mice. Mirella Giovarelli, Edward Padula. 3518 Localization of ["C]Nitro$onornicotme in Tissues of Glycoproteins during Chemical Hepatocarcinogene- Gianfranco Ugazio, Guido Form, and Giorgio Cavallo sis. R. J Stocken and F F Becker the Mouse. William J WaddeM and Carolyn Marlowe *3750 Phase I Study of 1-(2-Chloroethyl)-3-(2,6-dioxo-3-pi- peridylH-nitrosourea (NSC 95466) in Adults with 3524 Oxidative Metabolism of nf-lsopropyl-

XIV CANCER RESEARCH VOL. 40 Contents of Volume 40, 1980

Communications the Envelope Proteins of Murine Leukemia Virus. 2617. 1979. Jonathan J Li. Sara Antonia Li. Deanna J Milton R Tarn. William R Green, and Robert C Talley. and Hadiey Kirkman 3846 Synergistic Effect of a Choline-devoid Diet and PhÃ© Nowiriski Y C Lin and C A Villee nobarbital in Promoting the Emergence of Foci of -â€¢ Glutamyltranspeptidase-positive Hepatocytes in the 3854 Letter to the Editor 3859 Special Announcements Liver of Carcinogen-treated Rats. Hisashi Shinozuka Correspondence re: Young C. Lin. Deanna J. Talley. and Benito Lombardi and Claude A. Viiiee Increased Progesterone Recep 3860 Announcements tor Concentrations in Bladder Lesions of Estrogen- 3850 Cytotoxic Activities of Monoclonal Antibodies against treated Syrian Hamsters. Cancer Res.. 39; 2614- 3862 Author Index

November, Number 11

* 3863 Laboratory and Clinical Research in Breast Cancerâ€” 3988 Long-Term Effects on the Female Mouse Genital 41OO Regulation of Cyclic Adenosine 3 5 Monophos A Personal Adventure: The David A. Karnofsky Mem Tract Associated with Prenatal Exposure to Diethyl- phate-binding Protein in N-18 Mouse Neuroblastoma orial Lecture. Bernard Fisher stilbestrol. John A McLachlan. Retha R Newbold, and Cells. Alice Y -C Liu, William W Fiske. and Kuang Yu Bill C. Bullock Chen. 3875 Mesothelioma Associated with the Shipbuilding In dustry in Coastal Virginia. Isabel Tagnon. William J 40OO Altered 5-Azacytidine Metabolism Following 3-Dea- *41O9 Inhibition of Human Ovarian Cancer Colony Forma Blot. Robert B Stroube. Nicholas E. Day, Linda E zauridine Treatment of L5178Y and Human Myelo- tion by Adriamycin and Its Major Metabolites. Robert Morns. Barbara B Peace, and Joseph F Fraumeni. Jr blasts. Steven Grant and Ed Cadman F Ozols, James K V W.llson. Martin D Weltz. Karen 3880 Search for Retrovirus-like Particles in Human Breast 4007 Production of Human Chorionic Gonadotropin and Its R Grotzmger. Charles F Myers. Robert C Young Cancer Celts in Culture. James A StrÃ¤uchen.Suresh Subunits by Human Tumors Growing in Nude Mice. 4113 Assessment of Growth-limiting Events Caused by 5- K Arya. Tommie Sue Tralka. Linda W. Engel, and Raymond W Ruddon. Albert H Bryan, Kimberly S Fluorouracil in Mouse Cells and in Human Cells. R Nathaniel A. Young. Meade-Cobun. ano Vincent A. Pollack. Mark Evans. Jeffrey D Laskin, and Maire T Hakala 3886 Cell Cycle-specific Enhancement of Type C Virus 4013 Inhibition by Putrescine of the Induction of Epidermal 4123 Relative Cytotoxicity of 9-/Ã•-D-Arabi nofuranosylade- Activation by Sodium nf-Butyrate. Cednc W Long. Ornithine Decarboxylase Activity and Tumor Promo nine and 9-/i-o-Arabinofuranosyladenine 5'-Mono- William A Suk, Richard M. Snead. and Wayne L tion Caused by 12-O-Tetradecanoylphorbot-13-ace- phosphate. Peter Juranka and Voon-Loong Chan Christensen tate. Richard G Weekes, Ajit K Verma. and R K *4127 Comparison of Dextran-coated Charcoal and Sucrose Boutwell 3891 Mode of Inhibition of Tumor Cell Ribonucleotide Re- Density Gradient Analyses of Estrogen and Proges ductase by 2,3-Dihydro-1 M-pyrazolo(2,3-4]imidazole 4019 Influence of pH on the Response of Celts to Single terone Receptors in Human Breast Cancer. K M (NSC 51143). Joseph G Cory and Alfred E Fleischer and Split Doses of Hyperthermia. Leo E Gerweck. Anderson, P Bonomi. M Marogil. C Hendrickson. and 3895 Laser Flow Cytometric Studies on the Intracellular Maureen Jennings, and Barbara Richards S Economou Fluorescence of Anthracyclines. Awtar Knshan and 4133 Quantitative Assessment of Liver Colony Formation 4025 Effects of Adenosine Cyclic Nucleotides on the Syn Ram Ganapathi and Hepatocellular Carcinoma Incidence in Rats Re thesis of Human Chorionic Gonadotropin in Trans ceiving Intravenous Injections of Isogeneic Liver Cells 3901 Structural and Functional Effects of Adhamycin on formed Human Placental Cells. Janice Yang Chou Cardiac Cells in Vitro. Theodore J Lampidis. t. Craig Isolated during Hepatocarcinogenesis. Brian A Henderson. Mervyn Israel, and George P Canellos 4031 Some Circulating Factors Which Influence Granulo- Laishes and Phillip B Rolfe cytÂ«Â»-MonocyteProduction in the Chick with Myelo- 3910 Exceptionally High Tumor-initiating Activity of 4144 Metabolism in the F344 Rat of 4-(N-Methyl-N-nitro- blastic Leukemia. Debra Bryant, Ralph Smith, Stianta Benzo

DECEMBER 1980 XV Contents of Volume 40, 1980

4216 Cytotoxicity and ONA Cross-Linking Activity of 4-Sul- and Induction of Adenosinetriphosphatase-deficient lizuka. Hideki Nishikawa, Mitsunon Sakatani, Takeshi fidocyclophosphamides in Mouse Leukemia Cells Islands in Rat Liver. Takatoshi Ishikawa. Shozo Ogura, Fumio Hirao, and Yuichi Yamamura in Vitro. Leonard C Enckson, Lori M Ramonas. Daniel Takayama, and Tomoyuki Kitagawa. *4308 Clinicopathological Study of Gastric Cancers and S Zaharko. and Kurt W Kohn 4265 Quantitative Estimation of Cellular Retinoic Acid- Precancerous States Detected by Fetal Sulfoglyco- 4221 Cellular Binding Proteins for Vitamin A in Human binding Protein Activity in Normal, Dysplastic, and protein Antigen Screening. Ilkka P T HÃ¤kkinen,Rei|O Carcinomas and in Normal Tissues. Prabhudas R Neoplastic Human Breast Tissue. Willy M Kung. Eva Heinonen, Markku V Inberg. Osmo H Jarvi. Pekka Palan and Seymour L. Romney Geyer, Urs Eppenberger. and Peter R Huber Vaajalahti. and Sauli Vnkari 4225 Sedimentation of DNA from L1210 Cells alter Treat 4270 Erythrocyte Production and Survival in Rauscher Mu 4313 Excision of M-Acetoxy-2-acetylaminofluorene-in- ment with41 DÃ©methyleptpodophy llotoxm-9-<4.6- 0-2- rine Leukemia Virus-infected BALB/c Mice. N. J de duced DNA Adducts from Chromatin Fractions of thenylidene-/}-o-glucopyranoside) or l /( o-Arabi no- Both, E Kwak. and E Klootwijk-van Dijke Human Fibroblasts Motohisa Kaneko and Peter A Cerutti furanosylcytosine or Both Drugs. DeWayne Roberts, 4276 Structure of the Asparagine-linked Sugar Chains of Susan Milliard, and Charles Peck u-Fetoprotein Purified from Human Ascites Fluid. Communications 4232 Development and Characterization of Mouse Hyper- Hideo Yoshima. Tsuguo Mizuochi. Masaru Ishn. and 4320 Decreased Norepinephrine Concentration in Normal plastic Mammary Outgrowth Lines (rom 8ALB/cfC3H Akira Kobata Tissue Neighboring a Malignant Tumor. Thomas Hyperplastic Alveolar Nodules. Rhoda L. Ashley. 4282 In Vivo Study of Acute Hematotoxicity of Three Nitro- Borresen. Ã–leB Hennksen. and Niels J Christensen Roberto Cardiff. Dan J. Mitchell. Leslie J Faulkin, and soureas, Chlorozotocin, (Chloro-2-ethyl)-1-ribofura- 4322 Effect of Commercial Saccharin Preparations on Ur Judi K Lund nosyl-3-nitrosourea, and (Chloro-2-ethylM-ribopyra- ethan-induced Lung Tumorigenesis in Strain A Mice. Y4243 Biochemical, Pharmacological, and Phase I Clinical nosyl-3-nitrosourea. Katsuhiro J. Mori. Claude Jasmin. Jeffrey C. Theiss. Lyle J. Arnold, and Michael B Evaluation of Pseudoisocytidine. Thomas M Marcel Hayat, John S. MacDonald. and Georges MathÃ© Shimkm. Woodcock, Ttng-Chao Chou. Charlotte T C Tan. 4325 Stimulation by W'.O'-Dibutyryl Cyclic Adenosine 3': 4287 Experimental Model for Combination Chemotherapy 5'-Monophosphate of Ectopie Production of the Free Stephen S Sternberg, Frederick S Philips. Charles W with Metronidazole Using Human Uterine Cervical />'Subunit of Chorionic Gonadotropin by a Human Young, and Joseph H Burchenal Carcinomas Transplanted into Nude Mice. Hisashi Brain Tumor Cell Line. Saul W Rosen, Ida Calvert, * 4250 Phase I Clinical and Pharmacokinetic Study of 4'-(9- Tokita, Noboru Tanaka. Kazuyoshi Sekimoto. Tetsuo Ueno, Karoku Okamoto. and Shinji Fujimura. Bruce D Wemtraub. Jennifer S Tseng, and Alan S Acridinylamino)methanesulfon-m-anisidide in Chil Rabson *4295 Clonal Heterogeneity of Small-Cell Anaplastic Carci dren with Cancer. Gaston Rivera, William E. Evans, 4329 Induction of Epstein-Barr Virus Antigens in Human Gary V Dahl. Gary C. Yee, and Charles B Pratt noma of the Lung Demonstrated by Flow-Cytometric Lymphoblastoid P3HR-1 Cells with Culture Fluid of DNA Analysis. Lars L Vmdelov. Heme H Hansen. Ib J Fusobacterium nucleatum. Yohei Ito, Masamichi 4254 Progressive Loss of DNA and Lowering of the Chro Christensen. Mogens Spang-Thomsen. Fred R. Hirsch, Kishishita. and Sugio Yanase. mosomal Mode in Chemically Transformed C3H Mogens Hansen, and Mis I Nissen 10T-ÃŽCells during Development of Their Oncogenic 4331 Announcements Potential. Harald J K Saxholm and Vemund Digernes 4301 Differential Induction of Squamous Cell Carcinomas and Adenocaccinomas in Mouse Lung by Intratra- 4332 Author Index 4261 Correlation between Time of Partial Hepatectomy cheal Instillation of Benzo(s)pyrene and Charcoal 4333 Statement of Ownership, Management and Circula after a Single Treatment with Diethylnitrosamine Powder. Takahiko Yoshimoto. Tamotsu Inoue. Hidefumt tion

December, Number 12

*4335 Improving the Therapeutic Index in Breast Cancer tid Breaks Associated with DNA Repair Deficiency Mammalian Cells by a Non-Bay-Region Polycyclic Cy- Treatment: The Richard and Hinda Rosenthal Foun and Malignant Transformation in Culture. Ram clopenta(cd)pyrene and Its 3,4-Oxide. Avram Gold, dation Award Lecture. Samuel Hellman Parshad, Katherine K Sanford, Gary M Jones. Robert Stephen Nesnow. Martha Moore. Helen Garland. E Tarone, Harold A Hoffman, and Alice H. Grier GayneUe Curtis, Barry Howard, Delons Graham, and 4343 Nuclear Distribution of Aflatoxin B, and Its Interaction Eric Eisenstadt. with Histones in Rat Liver in Vivo. John D Groopman. *4420 Carcinoembryonic Antigen for Monitoring Patients William F. Busby. Jr . and Gerald N Wogan with Small-Cell Carcinoma of the Lung during Treat 4485 Thermotolerance as a Possible Cause of the Critical ment. T. Phillip Waalkes. Martin D Abeloft. Kwang B 4352 Promotion-like Enhancement of Trachea! Carcino- Temperature at 43 in Mammalian Cells. James R Woo, David S. Ettmger, Raymond W Ruddon. and Paul genesis in Rats by 12-O-Tetradecanoyl-phorbol-13- Lepock and Jack Kruuv Aldenderfer acetate. Douglas C Topping and Paul Nettesheim 4489 Uptake and Metabolism of Hexamethylmelamine and 4428 Detection of Early and Delayed Antitumor Effects 4356 Growth of Human Small-Ceil (Oat Cell) Carcinoma of Pentamethylmelamine by L5178Y Lymphoblasts in following Curative Adoptive Chemoimmunotherapy the Lung in Serum-free Growth Factor-supplemented Vitro. Asher Begleiter. Judy Grover. and Gerald J of Established Leukemia. Philip D Greenberg. Martin Goldenberg. Medium. Elisabeth Simms, Adi F Gazdar. Paul G A. Cheever. and Alexander Fefer Abrams, and John D Minna 4495 Inhibition of Human Lymphoblastoid Cell Line Prolif 4433 Differences in the Metabolism of 12-O-[3H]Tetra- eration by Ascites Fluids from Ovarian Cancer Pa 4364 Xenotropic Virus Expression and Susceptibility to 3- decanoylphorbol-13-acetate and [3H]Phorbol-12,13- Methylcholanthrene-mduced Cancer. KunjuramanT tients. Allan D Hess. Stanley A Gall, and Jeffrey R didecanoate by Cells in Culture. Thomas G O Brien Dawson Nayar, Jay A Levy. Barbara O Neill, and Richard E and Douglas Saladik Kouri 45O1 A Proposed Operational Model of Thermotolerance 4438 An in Vitro Assay Procedure to Test Chemotherapeu- Based on Effects of Nutrients and the Initial Treat 4368 Identification of Somatomedin-like Polypeptides Pro tic Drugs on Cells from Human Solid Tumors. Shashi ment Temperature. Gloria C Li and George M Hahn duced by Mammary Tumors of BALB/c Mice. D J Shnvastav, Robert A Bonar. Kenneth R. Stone, and Knauer, A P Iyer. M R Banerjee, and G L. Smith 4509 Preferential Sites of Growth of Human Tumors in David F Paulson Nude Mice following Subcutaneous Transplantation. 4373 Prolonged Ornithine Decarboxylase Induction in Re 4443 Activation of Cyclophosphamide for in Vitro Testing Aikatenni A Kynazis and Andreas P Kynazis. generating Carcinogen-treated Liver. Jack W Olson of Cell Sensitivity. Shashi Shnvastav. Kenneth R 4512 Specific Cytogenetic Changes in Ovarian Cancer and Diane Haddock Russell Stone. David F Paulson, and Robert A Bonar Involving Chromosomes 6 and 14. Nono Wake. 4381 Reduction of DNA Transforming Activity in Culture by 4446 Production of a Highly Reactive Alkytating Agent from Myroslaw M Hreshchyshyn. Steven M. Piver. Sei-ichi 6-Mercaptopurine. Douglas A Wetgent and J Arly the Organospecific Carcinogen Methylazoxymetha- Malsui. and Avery A Sandberg Nelson nol by Alcohol Dehydrogenase. Aaron Feinberg and 4519 Stimulation of Synthesis and Secretion of Chorionic Morris S. Zedeck 4385 Mitogenic Activity and PlasminogenActivator in Har Gonadotropin Subunits by Eutopic and Ectopie vest Fluid Concentrates from Mammary Cells in Cul 4451 Modification of Early DimethylhydrazineCarcinogen- Hormone-producing Human Cell Lines. Raymond ture. Eugene F Howard. Charles Y Cheng, and Joan esis by Colonie Mucosa! Hyperplasia. Stephen W W Ruddon. Carmen Anderson, and Kimberly S S Howard. Bartholdand DeborahBeck Meade-Cobun 439O Identification of the Antimetabolite of L-Alanosine. L- 4456 Catalysis of Divergent Pathways of 2-Acetylaminoflu- 4524 Effects of Urine and Continued Exposure to Carcin Alanosyl-5-amino-4-lmidazolecarboxylic Acid Riho orene Metabolism by Multiple Forms of Cytochrome ogen on Progression of Early Neoplastic Urinary nucleotide, in Tumors and Assessment of Its Inhibi P-450. Eric F. Johnson. David S Levitt, Ursula Muller- Bladder Lesions. Randall G. Rowland. Michael O tion of Adenylosuccinate Synthetase. Anil K Tyagi Eberhard, and Snorri S Thorgeirsson Henneberry. Ryoichi Oyasu, and John T Grayhack and David A Cooney 4460 Design of Liposomes to Improve Delivery of Macro- 4528 Identification of Mutagenic Dihydrodiols as Metab 4398 Distribution of DNA Polymerase Cm in Normal and phage-augmenting Agents to Alveolar Macrophages. olites of Benzo( ;)fluoranthene and Benzo( k} Malignant Human Tissues. Paul M Loewenstem. Gary I J Fidler. A Raz. W E Fogler. R Kirsh. P Bugelski, fluoranthene. Edmond J LaVoie, Stephen S Hecht. W Lange, and Gary F Gerard. and G Poste. Shantilal Amm. Victoria Bedenko. and Dietrich Hoffmann 4403 Isolation and Spontaneous Transformation of Cloned 4467 Duration of Cell Cycle and Its Phases Measured in 4533 Independence of Drug Action on Mitochondria and Lines of Hamster Trachea! Epithelial Cells. Brooke T Synchronized Cells of Squamous Cell Carcinoma of Mossman. Elizabeth B Ezerman. Kenneth B Adler, and Polyamines in L1210 Leukemia Cells Treated with Rat Trachea. Ronald E Gordon and Bernard P Lane Methyglyoxal-bis(guanylhydrazone). A Pleshkewych, John E Craighead 4473 Electron Microscopic and Peroxidase Cytochemical D L Kramer, E Kelly, and Carl W Porter Analysis of Pink Pseudo-Chediak-Higashi Granules in 4410 Multinucleation in the Presence of Cytochalasin B 4541 Stimulation of DNA Synthesis in Calcium-deprived by RNA Tumor Virus-transformed Cells. Kenneth D Acute Myelogenous Leukemia. William A Dittman. Somers and Margaret M Murphey Robert J Kramer, and Dorothy F Bamton T51B Liver Cells by the Tumor Promoters PhÃ©nobar bital, Saccharin, and 12-O-Tetradecanoyl-phorbol- 4415 Susceptibility to Fluorescent Light-induced Chroma- 4482 Mutagenesis and Morphological Transformation of 13-acetate. A L Boynton and J F. Whitfield.

XVI CANCER RESEARCH VOL. 40 Contents of Volume 40, 1980

*4546 Phase I Evaluation of Succinylated Acmetobacter 4663 Identification of Transformed Liver Cell Colonies Us Hapten-beanng Liposomes Containing Methotrexate Glutaminase-Asparaginase in Adults. Raymond P ing Concanavalin A Attached to Agarose Beads. P and Carboxyfluorescem. Lee D Leserman, John N Warrell, Jr . Ting-Chao Chou. Ciara Gordon. Charlotte Thomas lype and Carol H Pontzer Weinstein, John J Moore, and William D Terry Tan, Joseph Roberts. Stephen S Sternberg. Frederick 4669 Cytofluorescenc^ Localization of Anthracycline An 4775 Epstein-Barr Virus-transformed Human Lymphoblas- S Philips, and Charles W Young tibiotics. Merrill J Egonn, Ronald E Clawson. Jetfery toid Cella tor Study of Sister Chromatid Exchange 4552 Accumulation oÃActin Microfilaments in Adult Rat L Cohen. Louis A Ross and Nicholas R Bachur and Their Evaluation as a Test System. Hiroko Tohda, Hepatocytes Cultured on Collagen Gel/Nylon Mesh. Kalsuhiko Horaguchi. Kiyomi Takahashi. Atsushi W Wai-Nam Mak, Carol A Sattler, and Henry C Pitot 4677 Oxidoreductase Activities in Normal Rat Liver. Tu mor-bearing Rat Liver, and Hepatoma HC-252. Oikawa. and Taijiro Malsushima 4565 Effect of Polyethylene Glycol 60OOon the Generation Alexander S Sun and Arthur I Cederbautn 4781 Effect of Serial Passage in Female Nude Athymic of Antitumor Cytotoxicrty in MOPC-315 Tumor Bearer Mice on Androgen Dependency of Shionogi Carci Spleen Cells Cultured m the Presence or Absence 4682 New Doxorubicm Analogs Active against Doxorubi- noma 115. Yukihiko Kitamura. Naomi Uchida Isamu of Inactivated Stimulator Tumor Cells. Donna cm-resistant Colon Tumor Xenografts in the Nude Hayata, Kenji Yamaguchi. Shigeru Okamoto. Nonhiko Przepiorka, Margalit B Mokyr, and Sheldon Dray Mouse. Fernando C Giuliani and Nathan O Kaplan Nanta. and Keishi Matsumoto 4571 Development of an in Vitro and in Vivo Epithelial 4688 An Early Event Associated with Liver Carcmogenesis 4786 Sister Chromatid Exchanges and Chromosome Ab Tumor Model for the Study of Invasion. Bendichl U Involving Loss of a Polypeptide That Binds Carcino errations in Children after Treatment for Malignant PaulÂ«.Steven N Anderson. Vincent A Memoli. and gen. Gary R Blackburn, John P Andrews. K V Kesava Lymphoma. Ulla Haglund. Salah Hayder. and Lore Klaus E Kuettner Rao. and Sam Sorof Zech 4581 Comparison of Adriamycm- and Ouabain-mduced Cy- totoiicity and Inhibition of 'Rubidium Transport in 4694 A Survey of Transformation Markers in Differentiating 4791 Superoxide Assay-Leukocyte Adherence Inhibition Epidermal Cell Lines in Culture. Stuart H Yuspa. Wild-Type and Ouabain-resistant C3H/10T1; Mouse Test and a Soluble Factor Which Stimulates the Ad Pamela Hawley-Nelson. Barbara Koehler. and John R herence of Macrophages. Katsuro Yagawa, Manko Fibroblasts. Joseph R Landolph. Ram S Bhatt. Nancy Stanley Kaku. Hideo Manabe. Kosei Yasumoto. Harukazu Telfer, and Charles Heidelberger 47O4 Mutagemcity of Hydroxamic Acids and the Proba Mashiba. Hideaki Inbe. Jun Yamagata. Kenji Takenaka. 4589 Early Alterations m Rat Colonie Mucosa! Cyclic Nu ble Involvement of Carbamoylalion. Paul L Skipper. and Yasuo Nomura cleotide Metabolism and Protein Kinase Activity Steven R Tannenbaum. William G Thilly. Elizabeth E 4796 Site-directed Chromosome Rearrangements in Skin Induced by 1.2-Dimethylhydrazine. Frederick R Furth. and Walter W Bishop DeRubertis and Patricia A Craven Fibroblasts from Persons Carrying Genes tor Hered 4709 Effect of 12-O-Tetradecanoylphorbol-13-acetate on itary Neoplasms. M S Sasaki. Y Tsunemalsu, J 4599 Relative Importance of Bacterial and Mammalian Ni- the Morphology and Growth of CSH/IOT1? Mouse Utsunomiya. and J Utsumi troreductases for Niridazole Mutagenesis. Jeffrey Embryo Celts. Craig Boreiko. Sukdeb Mondai, K L Blumer. Allen Friedman, LeRoy W Meyer. Edward 48O4 Production by Mouse Spleen Cells of Factors Stimu Shankar Narayan. and Charles Heidelberger Fairchild. Leslie T Webster, Jr , and William T Speck lating Differentiation of Mouse Myeloid Leukemic 4717 Inhibition of 3-Hydroxy-3-methylglutaryl Coenzyme A Cells That Differ from the Colony-stimulating Factor. 4GO6 Dietary Control of Lipogenesis m Vivo m Host Tissues ReducÃaseActivity m Morris Hepatoma 78OO after and Tumors of Mice Bearing Ehrlich Ascites Carci Intravenous Injection of Mevalomc Acid. RaÃan noma. Ramaswamy Kannan. Irving Lyon, and Nome 4810 Preservation of Cell Cycle Characteristics in Solid George and Stanley Goldfarb Baker Tumor in Vitro. Kohsuke Sasaki and Manabu 4722 Specific Effects of Fibronectm-releasing Peptides on Takahashi 4612 Prediction of Survival in Gynecological Cancer Based the Extracellular Matrices of Cultured Human Fibro 4813 Effects of Levamisole Administration on Treatment on Immunological Tests. Irene J Check. Robert L blasto. Jorma Keski-Oja and George J Todaro with 6-Mercaptopunne Riboside of Mice Bearing Hunter. Karen 0 Rosenberg, and Arthur L Herbst L i 210 Leukemia Cells. Takaii Miura. Eisht Nogiwa 4728 Effect of Hyperglycemia on Blood Flow. pH. and 4617 Antitumor Activity of Corynebactenum parvum and Satonon Kurashige. and Tadashi Maekawa Retinyl Palmitate Used in Combination on the Lewis Response to Hyperthermia (42 } of the Yoshida Sar 4817 Effects of Retmoids on Normal and Neoplasttc Human Lung Carcinoma. Zlatko P Pavelic. Sulochana Dave. coma in the Rat. Stuart K Calderwood and John A Cells Cultured in Vitro. Elaine Lynette Wilson and Stanley Bialkowski. Roger L Priore, and William R Dickson Eugene B Oowdle Greco 4734 Quantification by Gas Chromatography of N. N'-Di-(2- 4622 Effects of Activated Macrophages on Tumor Target chloroethyl)phosphorodiamidic Acid in the Plasma of 4821 Relationship of Cytoplasmic and Nuclear Estrogen Patients Receiving Isophosphamide. Bruce M Bryant. Receptors and Progesterone Receptors in Human Cells in Discrete Phases of the Cell Cycle. James L Breast Cancer. Ranka Romic-Stojkovic and Stgepan Krahenbuhl Michael Jarman. Michael H Baker. Ian E Smith, and John F Smyth Gamulm 4628 Effect of Ovanectomy on Hormone Receptors and Growth of Af-Nitrosomethylurea-induced Mammary 4739 Effect of Partial Hepatectomy on the Response of Rat 4826 Meeting Report: Second International Workshop on Chromosomes in Leukemia. G Alimena, R Berger Tumors in the Rat. Baha uddm M Arafah. Pietro M Liver to Atlatoxm B,. G E Neal and J R P Cabrai H van den Berghe. G H Borgstrom L Brandt. D Cullino. Andrea Manni. and Olof H Pearson 4744 Factors Affecting the Expression of Carcmoem- Catovsky. A de la Chapelle. G W Dewald. O M 4631 Invasion of Endothelial Cell Monolayers on Collagen bryonic Antigen at the Surface of Cultured Human Garson. H M Golomb. D K Hossteld. S D Lawler. F Gels by Cells from Mammary Tumor Spheroids. Paul Colon Carcinoma Cells. Kenneth L Rosenthal. Wayne Mileiman, A van Orshoven. R V Pierre. J D Rowley. O Zamora, Keith G Danielson. and Howard L Hosick A F Tompkms. and William E Rawls M Sakurai. A A Sandberg. G Sokal. R Verwilghen. and P Vuopto * 4640 Reaction Patterns of Herpes Simplex Virus Type 1 4751 Mechanism of the Linkage between the Electropho- and Type 2 Proteins with Sera of Patients with Uterine ratic Mobility and Oxygen Uptake of Ascites Tumor 4828 Announcements Cells. Kaneat3u Miyamoto and Takeo Terasaki Cervical Carcinoma and Matched Controls. Steven C 4829 Recent Deaths Oilman. John J Docherty. Alleen Clarke, and William 4758 Lymph Node Metastasis and Effects of 1-/f-o-Arabi- E Rawls nofuranosylcytosme. 5-Fluorouracil. and Their Lipo- 4829 Erratum 4648 T-Lymphocyte Subpopulations in Peripheral Blood philic Derivatives in an Experimental Model System 4830 Acknowledgment to Reviewers and Tissues of Cancer Patients. Pawel A Using P388 Leukemia. Takashi Tsuruo. Kuniko Kaszubowski.GunnarHusby. K S K Tung, and Ralph Naganuma. Harumi lida. and Shigeru Tsukagoshi 4837 Author Index C Williams. Jr 4764 Calcitonin and 1.25-Dihydroxyvitamm [) Receptors 4839 Author Index to Volume 40 4658 Quantitation of Prostate-specific Antigen in Serum by in Human Breast Cancer Cell Lines. David M Fmdlay. Valdo P Michelangeli, John A Eisman. Richard J 4869 Subject Index to Volume 40 a Sensitive Enzyme Immunoassay. Manabu Kunyama, Frampton. Jane M Moseley. lam Maclntyre. Robert Ming C Wang. Lawrence D Papsidero. Carl S Killian, Wh.tehead. and T John Martin iii Contents of Volume 40 Takashi Shimano. Luis Valenzuela. Tsuneo Nishiura, Gerald P Murphy, and T Ming Chu 4768 Specific Interaction of Myeloma Tumor Cells with xvil Cover Illustrations for Volume 40

Cover Illustrations for 1980

January: Sidney Weinhouse. Editor of Cancer Research. a graph which shows worldwide incidence of lung cancer 1969-1979. among uranium miners. February: Louis S. Goodman and Alfred Gilman and the first August: Jean B. van Helmont and Paracelsus and the title page patient treated with the alkylating agent, nitrogen mus of Paracelsus Der grossen Wundartzney. tard. September: J C. Harshbarger and C J Dawe and three fish March: Cancer treatment and prevention center at Pondville with tumors of the head. October: M. Kaposi, a histolÃ³gica! section of Kaposi's sar Hospital in Norfolk. Mass, shown with E. M Daland, first coma, and a map in which Kaposi's sarcoma is com Chief of Staff and I. T. Nathanson and R. M Kelley. two key, long-term staff members. pared to all cancers in Negroes in Africa, April: J. C. Wagner. I. J. Selikoff, and E. C. Hammond on a November: Clinical investigators. J. C. Abels. K. Dobriner. and background of asbestos (chrysotile) fibers. D. A. Karnofsky. May: Norbert Brock and Asta-Werke in Bielefeld. Federal Re December: front cover. Recipients of General Motors Corp. public of Germany. Awards for excellence in cancer research. Isaac Beren- June: Eric Boyland and a scheme of probable pathways m blum. Elwood V. Jensen, and Elizabeth C. and James A. Miller; back cover. 'Island of Research" map depicts phenanthrene metabolism. July: V. E. Archer and G. Saccomanno, a uranium miner, and processes of research.

DECEMBER 1980 XVÃœ

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