applied sciences Review Oral Manifestations in Patients with Glycogen Storage Disease: A Systematic Review of the Literature 1, 1, 1 2 Antonio Romano y, Diana Russo y , Maria Contaldo , Dorina Lauritano , Fedora della Vella 3 , Rosario Serpico 1, Alberta Lucchese 1,* and Dario Di Stasio 1 1 Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “L. Vanvitelli”, Via Luigi De Crecchio 6, 80138 Naples, Italy;
[email protected] (A.R.);
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[email protected] (D.D.S.) 2 Department of Medicine and Surgery, Centre of Neuroscience of Milan, University of Milano-Bicocca, 20126 Milan, Italy;
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[email protected]; Tel.: +39-0815667670 Contributed equally to this article, so they are co-first authors. y Received: 28 August 2020; Accepted: 21 September 2020; Published: 25 September 2020 Abstract: (1) Background: Glycogen storage disease (GSD) represents a group of twenty-three types of metabolic disorders which damage the capacity of body to store glucose classified basing on the enzyme deficiency involved. Affected patients could present some oro-facial alterations: the purpose of this review is to catalog and characterize oral manifestations in these patients. (2) Methods: a systematic review of the literature among different search engines using PICOS criteria has been performed. The studies were included with the following criteria: tissues and anatomical structures of the oral cavity in humans, published in English, and available full text.