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Erectile Dysfunction and Cancer: Current Perspective Renu Madan, Chinna Babu Dracham, Divya Khosla, Shikha Goyal, Arun Kumar Yadav

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Erectile Dysfunction and Cancer: Current Perspective Renu Madan, Chinna Babu Dracham, Divya Khosla, Shikha Goyal, Arun Kumar Yadav pISSN 2234-1900 ROJ ROJ R O eISSN 2234-3156 J Radiation JournalRadiation Oncology Journal Oncology JournalRadiation Radiation Oncology Journal Radiation Oncology R a d i a t i o n O Oncology n c o l ogy J o urna l Journal Volume 38 Volume V Volume 37 • Number 4 • December 2019 2019 37 • Number 4 December Volume olume 33 • Number 3 · Number 3 · September 2020 September S ep t ember 2015 Pages 151-000 Pages Pages 232 - 308 Pages P a ges 16 1 -26 4 w www.e-roj.org www.e-roj.org w w . e - r o j Vol. 38, No. 4, December 2020 www.e-roj.org . Vol. 37, No. 4, December 2019 o r g The Korean Society for Radiation Oncology www.e-roj.org pISSN 2234-1900 eISSN 2234-3156 Vol. 38, No. 4, December 2020 Aims and Scope The Radiation Oncology Journal (ROJ) is an official journal of the Korean Society for Radiation Oncology. It was launched in 1983 as the official journal of the Korean Society of Therapeutic Radiology. It was changed in 2000 as the official journal of the Korean Society for Therapeutic Radiology and Oncology and finally in 2011 as ROJ. The aims of Radiation Oncology Journal are to contribute to the advancements in the fields of radiation oncology through the scientific reviews and interchange of all of radiation oncology. It encompasses all areas of radiation oncology that impacts on the treatment of cancer using radiation as well basic experimental work relating radiation oncology and health policy. It publishes papers describing clinical radiotherapy, combined modality therapy, radiation biology, cancer biology, radiation physics, radiation informatics and new technology including particle therapy. The ROJ is published quarterly on the last day of March, June, September, and December, one volume per year. Any physicians or researchers throughout the world can submit a manuscript if the scope of the manuscript is appropriate. Articles in the following categories will be published: original articles, invited review articles, case reports, editorials, and letters to the editor related to basic or clinical radiation oncology. All of the manuscripts are peer-reviewed. The ROJ is free open access journal. All articles published in ROJ are available through http://www.e-roj.org. Open Access This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Publisher Sung-Hwan Kim Editor-in-Chief Won Park Editorial office Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea Tel: +82-2-3410-2616 Fax: +82-2-3410-2619 E-mail: [email protected] Korean Society for Radiation Oncology Department of Radiation Oncology, St. Vincent Hospital, 93, Jungbu-daero, Paldal-gu, Suwon-si, Gyeonggi-do 16247, Republic of Korea Tel: +82-31-881-8566 E-mail: [email protected] Printing office M2community Co. 8th FL, DreamTower, 66 Seongsui-ro, Seongdong-gu, Seoul 04784, Korea Tel: +82-2-2190-7300 Fax: +82-2-2190-7333 E-mail: [email protected] Published on December 31, 2020 Copyright © 2020. The Korean Society for Radiation Oncology This paper meets the requirements of KS X ISO 9706, ISO 9706-1994 and ANSI/NISO Z39. 48-1992 (Permanence of paper) Editorial Board Publisher Sung-Hwan Kim The Catholic University of Korea, ST. Vincent’s Hospital Editor-in-Chief Won Park Sungkyunkwan University, Korea Associate Editor Sang Min Yoon University of Ulsan, Korea Editorial Board Zishan Allibhai Southlake Regional Health Centre, Canada Sevil Aliyeva Bagaturovna N. N. Blokhin Cancer Research Center, Russia Miriam Joy C. Calaguas St. Luke's Medical Center, Philippines Changhoon Choi Sungkyunkwan University, Korea Hak Choy UT Southweastern Medical Center, USA Mantana Dhanachai Mahidol University, Thailand Keun-Yong Eom Seoul National University Bundang Hospital, Korea Soehartati Gondhowiardjo University of Indonesia, Indonesia Chul Soo Ha The University of Texas Health Science Center at San Antonio, USA Ji Hong Hong Chang Gung Memorial Hospital, Taiwan Byoung Hyuck Kim SMG-SNU Boramae Medical Center, Korea Jin Sung Kim Yonsei University, Korea Kyubo Kim Ewha Womans University, Korea Tae Hyun Kim National Cancer Center, Korea Woong Sub Koom Yonsei University, Korea Hyung Sik Lee Dong-A University, Korea Jong Hoon Lee Catholic University, Korea Vedang Murthy Tata Memorial Centre, India O Kyu Noh Ajou University, Korea Dongryul Oh Sungkyunkwan University, Korea Umberto Ricardi University of Turin, Italy Vinay Sharma University of the Witwatersrand, South Africa Tarek Shouman Cairo University, Egypt Chang Won Song University of Minnesota, USA Ekkasit Tharavichitkul Chiang Mai University, Thailand Dang Huy Quoc Thinh HCMC Oncology Hospital, Vietnam Joseph Tien-Seng Wee National Cancer Center, Singapore Seung-Gu Yeo Soon Chun Hyang University, Korea Zhao Chong Zeng Fudan Univerisity, China Eduardo H. Zubizarreta International Atomic Energy Agency, Argentina Editorial Assistant Do Hee Kim KOSRO, Korea Manuscript Editor Ji Hye Kim Infolumi, Korea Radiat Oncol J eISSN 2234-3156 Vol. 38, No. 4, December 2020 Review Articles 217 Erectile dysfunction and cancer: current perspective Renu Madan, Chinna Babu Dracham, Divya Khosla, Shikha Goyal, Arun Kumar Yadav 226 Harnessing genome-wide association studies to minimize adverse radiation-induced side effects Cecil M. Benitez, Susan J. Knox Original Articles Clinical Investigations 236 Post-mastectomy radiation therapy in breast reconstruction: a patterns of care study of the Korean Radiation Oncology Group Gowoon Yang, Jee Suk Chang, Kyung Hwan Shin, Jin Ho Kim, Won Park, Haeyoung Kim, Kyubo Kim, Ik Jae Lee, Won Sup Yoon, Jihye Cha, Kyu-Chan Lee, Jin Hee Kim, Jin Hwa Choi, Sung-Ja Ahn, Boram Ha, Sun Young Lee, Dong Soo Lee, Jeongshim Lee, Sei One Shin, Yong Bae Kim 244 Prognostic significance of lymph node ratio after neoadjuvant chemoradiation therapy for esophageal squamous cell carcinoma Jeong Yun Jang, Jesang Yu, Kye Jin Song, Yoon young Jo, Ye Jin Yoo, Sung-Bae Kim, Sook Ryun Park, Young-Hee Kim, Hyeong Ryul Kim, Jong Hoon Kim 253 Prospective evaluation of fiducial marker placement quality and toxicity in liver CyberKnife stereotactic body radiotherapy Debnarayan Dutta, Kaushik Jagannath Kataki, Shibu George, Sruthi K. Reddy, Ajay Sashidharan, Rajesh Kannan, Ram Madhavan, Haridas Nair, Tushar Tatineni, Raghavendra Holla 262 Real world clinical outcomes of adjuvant sequential chemoradiation in patients with gallbladder carcinomas with poor performance status Rakesh Kapoor, Kannan Periasamy, Rajesh Gupta, Arun Yadav, Divya Khosla Physics Contribution 270 Dosimetric comparative study of 3DCRT, IMRT, VMAT, Ecomp, and Hybrid techniques for breast radiation therapy Semaya Natalia Chen, Prabhakar Ramachandran, Pradip Deb Copyright ⓒ 2020. The Korean Society for Radiation Oncology Radiat Oncol J eISSN 2234-3156 Vol. 38, No. 4, December 2020 Case Reports 282 Primary intracranial leiomyosarcoma presenting with frontal bone mass: a case report Shaghayegh Kamian, Abdolali Ebrahimi, Kaveh Ebrahim Zadeh, Behnaz Behzadi 287 Management of grade 3 acute dermatitis with moist desquamation after adjuvant chest wall radiotherapy: a case report Durim Delishaj, Romerai D’amico, Daniela Corvi, Giuseppe De Nobili, Alessandro Alghisi, Francesco Colangelo, Alessandra Cocchi, Fausto Declich, Carlo Pietro Soatti Copyright ⓒ 2020. The Korean Society for Radiation Oncology Review Article pISSN 2234-1900 · eISSN 2234-3156 Radiat Oncol J 2020;38(4):217-225 https://doi.org/10.3857/roj.2020.00332 Erectile dysfunction and cancer: current perspective Renu Madan1, Chinna Babu Dracham2, Divya Khosla1, Shikha Goyal1, Arun Kumar Yadav1 1Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India 2Department of Radiation Oncology, Queen’s NRI Hospital, Visakhapatnam, India Received: June 3, 2020 Revised: July 19, 2020 Erectile dysfunction (ED) is one of the major but underreported concerns in cancer patients and survi- Accepted: July 30, 2020 vors. It can lead to depression, lack of intimacy between the couple, and impaired quality of life. The causes of erectile dysfunction are psychological distress and endocrinal dysfunction caused by cancer Correspondence: itself or side effect of anticancer treatment like surgery, radiotherapy, chemotherapy and hormonal Chinna Babu Dracham therapy. The degree of ED depends on age, pre-cancer or pre-treatment potency level, comorbidities, Department of Radiation Oncology, type of cancer and its treatment. Treatment options available for ED are various pharmacotherapies, Queen’s NRI Hospital, mechanical devices, penile implants, or reconstructive surgeries. A complete evaluation of sexual Seethammadhara, Gurudwara lane, functioning should be done before starting anticancer therapy. Management should be individualized Visakhapatnam 530013, India and couple counseling should be an integral part of the anticancer treatment. Tel: +91-9855803437 E-mail: [email protected] Keywords: Erectile dysfunction, Neoplasm, Surgery, Radiotherapy ORCID: https://orcid.org/0000-0002-8921-0957 Introduction androgen deprivation therapy (ADT) and RP (with or without nerve sparing) was associated with higher incidence of sexual dysfunc- Cancer diagnosis and its management lead to physical and emo- tion. Incidence of ED in cancer patients has
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