Common Name: ISOAMYL

CAS Number: 123-92-2 DOT Number: UN 1104 RTK Substance number: 1038 DOT Hazard Class: 3 (Flammable Liquid) Date: May 1998 Revision: July 2005 ------

HAZARD SUMMARY * can affect you when breathed in. * If you think you are experiencing any work-related health * Contact can irritate the skin and eyes. problems, see a doctor trained to recognize occupational * Breathing Isoamyl Acetate can irritate the nose, throat diseases. Take this Fact Sheet with you. and lungs. * ODOR THRESHOLD = 0.22 ppm. * Exposure to high concentrations of Isoamyl Acetate can * The range of accepted odor threshold values is quite cause headache, drowsiness, dizziness, lightheadedness, broad. Caution should be used in relying on odor alone as fatigue, and may cause you to pass out. a warning of potentially hazardous exposures. * Prolonged or repeated contact can cause drying and cracking of the skin. WORKPLACE EXPOSURE LIMITS * Isoamyl Acetate is a FLAMMABLE LIQUID and a FIRE OSHA: The legal airborne permissible exposure limit HAZARD. (PEL) is 100 ppm averaged over an 8-hour workshift. IDENTIFICATION Isoamyl Acetate is a clear, colorless liquid with a banana-like NIOSH: The recommended airborne exposure limit is odor. It is used as a , in perfumes, and in artificial fruit 100 ppm averaged over a 10-hour workshift. flavorings. ACGIH: The recommended airborne exposure limit is REASON FOR CITATION 50 ppm averaged over an 8-hour workshift and * Isoamyl Acetate is on the Hazardous Substance List 100 ppm as a STEL (short term exposure limit).

because it is regulated by OSHA and cited by ACGIH, DOT, NIOSH and NFPA. WAYS OF REDUCING EXPOSURE * This chemical is on the Special Health Hazard Substance * Where possible, enclose operations and use local exhaust List because it is FLAMMABLE. ventilation at the site of chemical release. If local exhaust * Definitions are provided on page 5. ventilation or enclosure is not used, respirators should be worn. HOW TO DETERMINE IF YOU ARE BEING * Wear protective work clothing. * Wash thoroughly immediately after exposure to Isoamyl EXPOSED Acetate and at the end of the workshift. The New Jersey Right to Know Act requires most employers * Post hazard and warning information in the work area. In to label chemicals in the workplace and requires public addition, as part of an ongoing education and training employers to provide their employees with information and effort, communicate all information on the health and training concerning chemical hazards and controls. The safety hazards of Isoamyl Acetate to potentially exposed federal OSHA Hazard Communication Standard, 1910.1200, requires private employers to provide similar training and workers. information to their employees.

* Exposure to hazardous substances should be routinely evaluated. This may include collecting personal and area air samples. You can obtain copies of sampling results from your employer. You have a legal right to this information under OSHA 1910.1020. ISOAMYL ACETATE page 2 of 6

This Fact Sheet is a summary source of information of all WORKPLACE CONTROLS AND PRACTICES potential and most severe health hazards that may result from exposure. Duration of exposure, concentration of the substance Unless a less toxic chemical can be substituted for a hazardous and other factors will affect your susceptibility to any of the substance, ENGINEERING CONTROLS are the most potential effects described below. effective way of reducing exposure. The best protection is to ------enclose operations and/or provide local exhaust ventilation at the site of chemical release. Isolating operations can also HEALTH HAZARD INFORMATION reduce exposure. Using respirators or protective equipment is less effective than the controls mentioned above, but is Acute Health Effects sometimes necessary. The following acute (short-term) health effects may occur immediately or shortly after exposure to Isoamyl Acetate: In evaluating the controls present in your workplace, consider: (1) how hazardous the substance is, (2) how much of the * Contact can irritate the skin and eyes. substance is released into the workplace and (3) whether * Breathing Isoamyl Acetate can irritate the nose and throat. harmful skin or eye contact could occur. Special controls * Exposure to high concentrations of Isoamyl Acetate can should be in place for highly toxic chemicals or when cause headache, drowsiness, dizziness, lightheadedness, significant skin, eye, or breathing exposures are possible.

fatigue, and may cause you to pass out. In addition, the following controls are recommended:

Chronic Health Effects * Where possible, automatically pump liquid Isoamyl The following chronic (long-term) health effects can occur at Acetate from drums or other storage containers to process some time after exposure to Isoamyl Acetate and can last for containers. months or years: * Before entering a confined space where Isoamyl Acetate Cancer Hazard may be present, check to make sure that an explosive concentration does not exist. * According to the information presently available to the New

Jersey Department of Health and Senior Services, Isoamyl Good WORK PRACTICES can help to reduce hazardous Acetate has not been tested for its ability to cause cancer in exposures. The following work practices are recommended: animals.

Reproductive Hazard * Workers whose clothing has been contaminated by Isoamyl Acetate should change into clean clothing promptly. * According to the information presently available to the New * Contaminated work clothes should be laundered by Jersey Department of Health and Senior Services, Isoamyl individuals who have been informed of the hazards of Acetate has not been tested for its ability to affect exposure to Isoamyl Acetate. reproduction. * Eye wash fountains should be provided in the immediate

work area for emergency use. Other Long-Term Effects * If there is the possibility of skin exposure, emergency * Breathing Isoamyl Acetate can irritate the lungs causing shower facilities should be provided. coughing and/or shortness of breath. * On skin contact with Isoamyl Acetate, immediately wash * Prolonged or repeated contact can cause drying and or shower to remove the chemical. At the end of the cracking of the skin. workshift, wash any areas of the body that may have contacted Isoamyl Acetate, whether or not known skin MEDICAL contact has occurred. * Do not eat, smoke, or drink where Isoamyl Acetate is Medical Testing handled, processed, or stored, since the chemical can be There is no special test for this chemical. However, if illness swallowed. Wash hands carefully before eating, drinking, occurs or overexposure is suspected, medical attention is smoking, or using the toilet. recommended. PERSONAL PROTECTIVE EQUIPMENT Any evaluation should include a careful history of past and present symptoms with an exam. Medical tests that look for WORKPLACE CONTROLS ARE BETTER THAN damage already done are not a substitute for controlling PERSONAL PROTECTIVE EQUIPMENT. However, for exposure. some jobs (such as outside work, confined space entry, jobs done only once in a while, or jobs done while workplace Request copies of your medical testing. You have a legal right controls are being installed), personal protective equipment to this information under OSHA 1910.1020. may be appropriate.

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OSHA 1910.132 requires employers to determine the * Exposure to 1,000 ppm is immediately dangerous to life appropriate personal protective equipment for each hazard and and health. If the possibility of exposure above 1,000 ppm to train employees on how and when to use protective exists, use a NIOSH approved self-contained breathing equipment. apparatus with a full facepiece operated in a pressure- demand or other positive-pressure mode equipped with an The following recommendations are only guidelines and may emergency escape air cylinder. not apply to every situation. HANDLING AND STORAGE Clothing * Avoid skin contact with Isoamyl Acetate. Wear solvent- * Prior to working with Isoamyl Acetate you should be resistant gloves and clothing. Safety equipment suppliers/ trained on its proper handling and storage. manufacturers can provide recommendations on the most * Isoamyl Acetate is not compatible with METALS; protective glove/clothing material for your operation. OXIDIZING AGENTS (such as PERCHLORATES, * Safety equipment manufacturers recommend Polyvinyl PEROXIDES, PERMANGANATES, CHLORATES, Alcohol and Nitrile as protective materials. NITRATES, CHLORINE, BROMINE and FLUORINE); * All protective clothing (suits, gloves, footwear, headgear) STRONG ACIDS (such as HYDROCHLORIC, should be clean, available each day, and put on before SULFURIC and NITRIC); and STRONG BASES (such as work. SODIUM HYDROXIDE and POTASSIUM HYDROXIDE). Eye Protection * Store in tightly closed containers in a cool, well-ventilated * Wear indirect-vent, impact and splash resistant goggles area away from COMBUSTIBLES. when working with liquids. * Sources of ignition, such as smoking and open flames, are * Wear a face shield along with goggles when working with prohibited where Isoamyl Acetate is used, handled, or corrosive, highly irritating or toxic substances. stored. * Metal containers involving the transfer of Isoamyl Acetate Respiratory Protection should be grounded and bonded. IMPROPER USE OF RESPIRATORS IS DANGEROUS. * Use only non-sparking tools and equipment, especially Such equipment should only be used if the employer has a when opening and closing containers of Isoamyl Acetate. written program that takes into account workplace conditions, requirements for worker training, respirator fit testing and QUESTIONS AND ANSWERS medical exams, as described in OSHA 1910.134. Q: If I have acute health effects, will I later get chronic * Where the potential exists for exposure over 50 ppm, use a health effects? MSHA/NIOSH approved full facepiece respirator with an A: Not always. Most chronic (long-term) effects result from organic vapor cartridge. Increased protection is obtained repeated exposures to a chemical. from full facepiece powered-air purifying respirators.

* If while wearing a filter or cartridge respirator you can Q: Can I get long-term effects without ever having short- smell, taste, or otherwise detect Isoamyl Acetate, or if term effects? while wearing particulate filters abnormal resistance to A: Yes, because long-term effects can occur from repeated breathing is experienced, or eye irritation occurs while exposures to a chemical at levels not high enough to make wearing a full facepiece respirator, leave the area you immediately sick. immediately. Check to make sure the respirator-to-face seal

is still good. If it is, replace the filter or cartridge. If the Q: What are my chances of getting sick when I have been seal is no longer good, you may need a new respirator. exposed to chemicals? * Be sure to consider all potential exposures in your A: The likelihood of becoming sick from chemicals is workplace. You may need a combination of filters, increased as the amount of exposure increases. This is prefilters or cartridges to protect against different forms of a determined by the length of time and the amount of chemical (such as vapor and mist) or against a mixture of material to which someone is exposed. chemicals.

* Where the potential for high exposure exists, use a MSHA/NIOSH approved supplied-air respirator with a full Q: When are higher exposures more likely? facepiece operated in a pressure-demand or other positive- A: Conditions which increase risk of exposure include pressure mode. For increased protection use in combination physical and mechanical processes (heating, pouring, with an auxiliary self-contained breathing apparatus spraying, spills and evaporation from large surface areas operated in a pressure-demand or other positive-pressure such as open containers), and "confined space" exposures mode. (working inside vats, reactors, boilers, small rooms, etc.).

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Q: Is the risk of getting sick higher for workers than for ------community residents? The following information is available from: A: Yes. Exposures in the community, except possibly in cases of fires or spills, are usually much lower than those New Jersey Department of Health and Senior Services found in the workplace. However, people in the Occupational Health Service community may be exposed to contaminated water as PO Box 360 well as to chemicals in the air over long periods. This Trenton, NJ 08625-0360 may be a problem for children or people who are already (609) 984-1863 ill. (609) 984-7407 (fax)

Web address: http://www.state.nj.us/health/eoh/odisweb/

Industrial Hygiene Information Industrial hygienists are available to answer your questions regarding the control of chemical exposures using exhaust ventilation, special work practices, good housekeeping, good hygiene practices, and personal protective equipment including respirators. In addition, they can help to interpret the results of industrial hygiene survey data.

Medical Evaluation If you think you are becoming sick because of exposure to chemicals at your workplace, you may call personnel at the Department of Health and Senior Services, Occupational Health Service, who can help you find the information you need.

Public Presentations Presentations and educational programs on occupational health or the Right to Know Act can be organized for labor unions, trade associations and other groups.

Right to Know Information Resources The Right to Know Infoline (609) 984-2202 can answer questions about the identity and potential health effects of chemicals, list of educational materials in occupational health, references used to prepare the Fact Sheets, preparation of the Right to Know Survey, education and training programs, labeling requirements, and general information regarding the Right to Know Act. Violations of the law should be reported to (609) 984-2202. ------

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DEFINITIONS

ACGIH is the American Conference of Governmental NAERG is the North American Emergency Response Industrial Hygienists. It recommends upper limits (called Guidebook. It was jointly developed by Transport Canada, the TLVs) for exposure to workplace chemicals. United States Department of Transportation and the Secretariat of Communications and Transportation of Mexico. It is a A carcinogen is a substance that causes cancer. guide for first responders to quickly identify the specific or generic hazards of material involved in a transportation The CAS number is assigned by the Chemical Abstracts incident, and to protect themselves and the general public Service to identify a specific chemical. during the initial response phase of the incident.

CFR is the Code of Federal Regulations, which consists of the NFPA is the National Fire Protection Association. It classifies regulations of the United States government. substances according to their fire and explosion hazard.

A combustible substance is a solid, liquid or gas that will burn. NIOSH is the National Institute for Occupational Safety and Health. It tests equipment, evaluates and approves respirators, A corrosive substance is a gas, liquid or solid that causes conducts studies of workplace hazards, and proposes standards irreversible damage to human tissue or containers. to OSHA.

DEP is the New Jersey Department of Environmental NTP is the National Toxicology Program which tests Protection. chemicals and reviews evidence for cancer.

DOT is the Department of Transportation, the federal agency OSHA is the Occupational Safety and Health Administration, that regulates the transportation of chemicals. which adopts and enforces health and safety standards.

EPA is the Environmental Protection Agency, the federal PEL is the Permissible Exposure Limit which is enforceable by agency responsible for regulating environmental hazards. the Occupational Safety and Health Administration.

A fetus is an unborn human or animal. PIH is a DOT designation for chemicals which are Poison Inhalation Hazards. A flammable substance is a solid, liquid, vapor or gas that will ignite easily and burn rapidly. ppm means parts of a substance per million parts of air. It is a measure of concentration by volume in air. The flash point is the temperature at which a liquid or solid gives off vapor that can form a flammable mixture with air. A reactive substance is a solid, liquid or gas that releases energy under certain conditions. IARC is the International Agency for Research on Cancer, a scientific group that classifies chemicals according to their STEL is a Short Term Exposure Limit which is usually a 15- cancer-causing potential. minute exposure that should not be exceeded at any time during a work day. IRIS is the Integrated Risk Information System database of the federal EPA. A teratogen is a substance that causes birth defects by damaging the fetus. A miscible substance is a liquid or gas that will evenly dissolve in another. TLV is the Threshold Limit Value, the workplace exposure limit recommended by ACGIH. mg/m3 means milligrams of a chemical in a cubic meter of air. It is a measure of concentration (weight/volume). The vapor pressure is a measure of how readily a liquid or a solid mixes with air at its surface. A higher vapor pressure A mutagen is a substance that causes mutations. A mutation is indicates a higher concentration of the substance in air and a change in the genetic material in a body cell. Mutations can therefore increases the likelihood of breathing it in. lead to birth defects, miscarriages, or cancer.

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Common Name: ISOAMYL ACETATE ======DOT Number: UN 1104 FOR LARGE SPILLS AND FIRES immediately call your fire DOT Hazard Class: 3 (Flammable Liquid) department. You can request emergency information from the NAERG Code: 129 following: CAS Number: 123-92-2 CHEMTREC: (800) 424-9300 NJDEP HOTLINE: 1-877-WARN-DEP Hazard rating NJDHSS NFPA ======FLAMMABILITY - 3 (See page 3) - 0 HANDLING AND STORAGE REACTIVITY FLAMMABLE FIRST AID POISONOUS GASES ARE PRODUCED IN FIRE CONTAINERS MAY EXPLODE IN FIRE For POISON INFORMATION call 1-800-222-1222

Hazard Rating Key: 0=minimal; 1=slight; 2=moderate; Eye Contact 3=serious; 4=severe * Immediately flush with large amounts of water for at least 15 minutes, occasionally lifting upper and lower lids. FIRE HAZARDS Skin Contact * Isoamyl Acetate is a FLAMMABLE LIQUID. * Remove contaminated clothing. Wash contaminated skin * Use dry chemical, CO2, alcohol-resistant foam or other with soap and water. foaming agent, as water may not be effective in fighting fires. Breathing * POISONOUS GASES ARE PRODUCED IN FIRE. * Remove the person from exposure. * CONTAINERS MAY EXPLODE IN FIRE. * Begin rescue breathing (using universal precautions) if * Use water spray to keep fire-exposed containers cool. breathing has stopped and CPR if heart action has stopped. * Vapors may travel to a source of ignition and flash back. * Transfer promptly to a medical facility. * Vapor is heavier than air and may travel a distance to cause a fire or explosion far from the source. PHYSICAL DATA * If employees are expected to fight fires, they must be trained and equipped as stated in OSHA 1910.156. Vapor Pressure: 4 mm Hg at 68oF (20oC) o o SPILLS AND EMERGENCIES Flash Point: 77 F (25 C) Water : Slightly soluble If Isoamyl Acetate is spilled or leaked, take the following steps: OTHER COMMONLY USED NAMES

* Evacuate persons not wearing protective equipment from Chemical Name: area of spill or leak until clean-up is complete. 1-Butanol, 3-Methyl-, Acetate * Remove all ignition sources. Other Names: * Cover with an activated charcoal adsorbent and place in Banana Oil; 3-Methyl-1-Butyl Acetate; Isopentyl Acetate covered containers for disposal. * Ventilate and wash area after clean-up is complete. ------* Keep Isoamyl Acetate out of a confined space, such as a Not intended to be copied and sold for commercial sewer, because of the possibility of an explosion, unless the sewer is designed to prevent the build-up of explosive purposes. concentrations. ------* It may be necessary to contain and dispose of Isoamyl NEW JERSEY DEPARTMENT OF HEALTH AND Acetate as a HAZARDOUS WASTE. Contact your state SENIOR SERVICES Right to Know Program Department of Environmental Protection (DEP) or your PO Box 368, Trenton, NJ 08625-0368 regional office of the federal Environmental Protection (609) 984-2202 Agency (EPA) for specific recommendations. ------* If employees are required to clean-up spills, they must be properly trained and equipped. OSHA 1910.120(q) may be applicable.