(SPIA) Terminology and Codes Requesting Pathology

Standards for Pathology Informatics

in Australia (SPIA)

Terminology and Codes Requesting Pathology

(v3.0)

Superseding and incorporating the Australian Pathology Units and Terminology Standards and Guidelines (APUTS)

ISBN: Pending

State Health Publication Number (SHPN): Pending

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Apart from any use as permitted under the Copyright Act 1968 or as set out above, all other rights are reserved. Requests and inquiries concerning reproduction and rights should be addressed to RCPA, 207 Albion St, Surry Hills, NSW 2010, Australia.

This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, LOINC panels and forms file, LOINC linguistic variants file, LOINC/RSNA Radiology Playbook, and LOINC/IEEE Medical Device Code Mapping Table are copyright © 1995-2016, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/terms-of-use.”

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO®). All rights reserved. SNOMED CT was originally created by The College of American Pathologists. IHTSDO®, SNOMED® and SNOMED CT® are registered trademarks of the IHTSDO.

This product includes all or a portion of the UCUM table, UCUM codes, and UCUM definitions or is derived from it, subject to a license from Regenstrief Institute, Inc. and The UCUM Organization. Your use of the UCUM table, UCUM codes, UCUM definitions also is subject to this license, a copy of which is available at http://unitsofmeasure.org. The current complete UCUM table, UCUM Specification are available for download at http://unitsofmeasure.org. The UCUM table and UCUM codes are copyright © 1995-2009, Regenstrief Institute, Inc. and the Unified Codes for Units of Measures (UCUM) Organization. All rights reserved.

First published: February, 2013, 1st Edition (version 1.0)

Standards for Pathology Informatics in Australia (SPIA) Previously known as the Australian Pathology Units and Terminology Standards and Guidelines (APUTS) Terminology for Requesting Pathology Copyright © 2013- 2017 RCPA. All rights reserved. This material contains information which is protected by copyright. You may download, display, print and reproduce any material for your personal, non-commercial use or use within your organisation subject to the following terms and conditions: 1. The material may not be copied, reproduced, communicated or displayed, in whole or in part, for profit or commercial gain. 2. Any copy, reproduction or communication must include this RCPA copyright notice in full. 3. No changes may be made to the wording of the Standards and Guidelines, terminology reference sets and information models including commentary, tables or diagrams. Excerpts from the Standards and Guidelines, terminology reference sets and information models may be used. References and acknowledgments must be maintained in any reproduction or copy in full or part of the material. Apart from any use as permitted under the Copyright Act 1968 or as set out above, all other rights are reserved. Requests and inquiries concerning reproduction and rights should be addressed to RCPA, 207 Albion St, Surry Hills, NSW 2010, Australia. This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO®). All rights reserved. SNOMED CT was originally created by The College of American Pathologists. IHTSDO®, SNOMED® and SNOMED CT® are registered trademarks of the IHTSDO.

TRIM Document #: D156353

Document History: Version Reason for Change Author Date Michael Legg / Dr Initial Terminology for Requesting pathology, published by the RCPA Pathology Units and Terminology 1.0 Christiaan 12-Feb-13 Standardisation Project. Swanepoel 2.0 Added Document Revision History worksheet. Donna Moore 06-Jun-14 Changed the filename from "PUTS Terminology for Requesting Pathology Subset " to "APUTS Requesting Pathology terminology reference set". Added additional SNOMED codes to this list after review from WG2 from PITUS project. Added "WBC Diff; Differential" to synonyms for White cell count. 2.1 After public feedback and approval by PITUS steering committee the following changes were made: Donna Moore 06-Nov-14 - Changed preferred name to 'Thrombin time' (was 'Thrombin') . - Changed the preferred name for a number of newly added v2.0 tests, refer to those tests marked with '2.1' in the version column.

3.0 Updated and new tests added, refer to '3.0' in the 'Version' and 'History' fields for details. Donna Moore 10-Jan-16 Updated after public comments. Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History 11-Deoxycortisol 16 Serum 313778009 | Serum 11-deoxycortisol measurement | 3.0 3.0 - Added by PITUS-16 project

11-Deoxycortisol urine 22 Urine 444132007 | Quantitative measurement of 11- 3.0 3.0 - Added by PITUS-16 project deoxycortisol in urine specimen | 14-3-3 protein CSF 14-3-3 protein cerebrospinal fluid; CJD 18 CSF 430551003 | Measurement of 14-3-3 protein 3.0 3.0 - Added by PITUS-16 project protein; Creutzfeldt-Jakob disease protein concentration in cerebrospinal fluid |

17-Hydroxypregnenolone 17 OH Pregnenolone 22 Serum 104447005 | 17-Hydroxypregnenolone measurement | 3.0 3.0 - Added by PITUS-16 project

17-Hydroxyprogesterone 17 OH Progesterone; 17-OHP; Hydroxy 22 Serum 41668001 | 17 Hydroxyprogesterone measurement, 2.1 2.1 - Changed preferred term from '17-Hydroxprogesterone' Progesterone serum | 2.0 - Added by PITUS-14 Working group 2 21-Hydroxylase Ab 18 Serum 117889006 | Measurement of 21-hydroxylase antibody 3.0 3.0 - Added by PITUS-16 project | 3-Hydroxy-3-methylglutarate 27 Serum 121893007 | 3-Hydroxy,3-methylglutarate 3.0 3.0 - Added by PITUS-16 project measurement | 3-Methoxytyramine 3-MT 17 Plasma 801311000168102 | Measurement of 3- 3.0 3.0 - Added by PITUS-16 project methoxytyramine in plasma specimen | 3-Methoxytyramine urine 3-MT urine 23 Urine 394952009 | Urine 3-methoxytyramine/creatinine 3.0 3.0 - Added by PITUS-16 project ratio | 3-Methoxytyramine urine 24h 3-MT 24 hr urine 27 Urine 394951002 | 24 hour urine 3-methoxytyramine output 3.0 3.0 - Changed preferred term from '3-Methoxythyramine'; Added | synonym 2.0 - Added by PITUS-14 Working group 2 4-Hydroxy-3-methoxymandelate urine 24h 3-Methyl,4-hydroxymandelate; HMMA urine 38 24 hr urine 121302000 | 3-Methyl,4-hydroxymandelate 3.0 3.0 - Added by PITUS-16 project measurement| 5HIAA urine 5 indole acetic acid 11 Urine 104741005 | 5-Hydroxyindoleacetic acid measurement 2.0 2.0 - Added by PITUS-14 Working group 2 | 5-Nucleotidase 14 Serum 2507007 | 5' Nucleotidase measurement | 3.0 3.0 - Added by PITUS-16 project Acanthamoeba culture Acanthamoeba detection 20 122192001 | Acanthamoeba species culture | 3.0 3.0 - Added by PITUS-16 project Acanthamoeba nucleic acid Acanthamoeba PCR; Acanthamoeba 25 122408004 | Acanthamoeba species identification | 3.0 3.0 - Added by PITUS-16 project detection Acetylcholine receptor Ab AChR Ab; Myasthenia gravis antibodies; 25 Serum 122224000 | Measurement of acetylcholine receptor 3.0 3.0 - Added synonym 'Myasthenia antibodies' AChR antibodies; Myasthenia antibodies antibody | 2.1 - Changed preferred term from 'Acetylcholine Receptor Ab' 2.0 - Added by PITUS-14 Working group 2

Acid fast bacilli culture AFB culture; non-tuberculous mycobacteria; 25 Urine; CSF; 117769004 | Acid fast bacteria identification | 3.0 3.0 - Added by PITUS-16 project M. ulcerans; M. abscessus; Atypical Tissue; Sputa; mycobacteria; Rapid growers Skin; Swabs; Fluids Acid fast bacilli microscopy AFB microscopy 28 Urine; CSF 391483001 | Microscopy (acid fast bacilli) | 3.0 3.0 - Added by PITUS-16 project Acid fast bacilli nucleic acid Acid fast bacilli PCR; Mycobacterium PCR; TB 30 766101000168107 | Acid fast bacilli nucleic acid assay 3.0 3.0 - Added by PITUS-16 project PCR; MAC PCR; Mycobacterium avium | complex PCR Acinetobacter sp screen Infection control screen 23 413063005 | Acinetobacter species screening test | 3.0 3.0 - Added by PITUS-16 project

ACTH Adrenocorticotropic hormone 4 Serum 49466006 | Adrenocorticotropic hormone 2.0 2.0 - Added by PITUS-14 Working group 2 measurement | Activated clotting time ACT; Activated coagulation time 23 69874005 | Coagulation time, activated | 3.0 3.0 - Added by PITUS-16 project Active vitamin B12 Holotranscobalamin; Active B12 18 Serum 439568007 | Measurement of holotranscobalamin 3.0 3.0 - Added synonym 'Active B12' concentration | 1.0 - Added by PUTS project Adenosine deaminase pleural fluid 33 Pleural fluid 104471003 | Adenosine deaminase measurement | 3.0 3.0 - Added by PITUS-16 project

Adenovirus Ab Adenovirus antibodies 13 Serum 104311005 | Measurement of adenovirus antibody | 3.0 3.0 - Added by PITUS-16 project

Adenovirus Ag faeces 20 Faeces 121960004 | Adenovirus antigen assay | 3.0 3.0 - Changed preferred term from 'Adenovirus Ag Faeces' 1.0 - Added by PUTS project Adenovirus nucleic acid 23 413450008 | Adenovirus nucleic acid detection | 3.0 3.0 - Added by PITUS-16 project Adiponectin 11 818941000168106 | Adiponectin measurement | 3.0 3.0 - Added by PITUS-16 project Adrenal Ab Adrenal antibodies 10 Serum 104391006 | Adrenal cortex antibody measurement | 3.0 3.0 - Added by PITUS-16 project

Adrenaline 10 Plasma 313620009 | Plasma adrenaline measurement | 3.0 3.0 - Added by PITUS-16 project Adrenaline urine 24h Epinephine 24 hr urine 20 24 hr urine 313968000 | 24 hour urine free adrenaline output 3.0 3.0 - Changed preferred term from 'Adrenaline 24 hr urine' measurement | 2.0 - Added by PITUS-14 Working group 2 Alanine aminotransferase ALT; Alanine transaminase; Glutamic pyruvic 24 Serum 250637003 | ALT - blood measurement | 1.0 1.0 - Added by PUTS project transaminase; SGPT Albumin Alb 7 Serum 104485008 | Albumin measurement, serum | 1.0 1.0 - Added by PUTS project Albumin CSF Cerebrospinal fluid albumin; CSF Albumin 11 CSF 313773000 | Cerebrospinal fluid albumin 2.0 2.0 - Added by PITUS-14 Working group 2 measurement | Albumin urine 24h Albumin 24 hour urine; 24 hr urine Albumin 17 24 hr urine 313502007 | 24 hour urine albumin output 3.0 3.0 - Changed preferred term from 'Albumin 24 hr urine' measurement | 2.0 - Added by PITUS-14 Working group 2 Aldolase 8 79676006 | Aldolase measurement | 3.0 3.0 - Added by PITUS-16 project Aldosterone 11 Serum 42379004 | Aldosterone measurement, serum | 2.0 2.0 - Added by PITUS-14 Working group 2 Aldosterone urine 17 Urine 88820003 | Aldosterone measurement, urine | 3.0 3.0 - Added by PITUS-16 project Aldosterone/renin ratio 23 Plasma 407693005 | Plasma aldosterone/renin ratio | 3.0 3.0 - Added by PITUS-16 project Alkaline phosphatase ALP; Alk phos 20 Serum 271234008 | Serum alkaline phosphatase 1.0 1.0 - Added by PUTS project measurement | Alkaline phosphatase isoenzymes ALP isoenzymes 31 Serum 8244002 | Alkaline phosphatase isoenzymes 3.0 3.0 - Added by PITUS-16 project measurement | Alpha subunit HCG alpha subunit; Alpha subunit 13 Serum 117700002 | Pituitary glucoprotein hormone, alpha 3.0 3.0 - Added by PITUS-16 project glycoprotein; Chorionic gonadotropin, alpha subunit measurement | subunit Alpha subunit glycoprotein 26 Serum 18691004 | Alpha-subunit of pituitary glycoprotein 3.0 3.0 - Added by PITUS-16 project hormone measurement | Alpha-1-antitrypsin A1AT; AAT 19 Serum 270976003 | Serum A1 antitrypsin measurement | 1.0 1.0 - Added by PUTS project Alpha-1-antitrypsin faeces Faecal A1 antitrypsin 26 Faeces 313955008 | Faecal A1 antitrypsin measurement | 3.0 3.0 - Added by PITUS-16 project Alpha-1-antitrypsin genotype 28 443342006 | Determination of alpha-1-antitrypsin 3.0 3.0 - Added by PITUS-16 project genotype | Alpha-1-antitrypsin phenotype 29 88884005 | Alpha-1-antitrypsin phenotyping | 3.0 3.0 - Added by PITUS-16 project Alpha-1-microglobulin urine A1M 27 Urine 765901000168101 | Alpha-1-microglobulin 3.0 3.0 - Added by PITUS-16 project measurement, urine | Alpha-fetoprotein AFP 18 Serum 104404005 | Alpha-1-fetoprotein measurement, serum 1.0 1.0 - Added by PUTS project | Alpha-fetoprotein amniotic fluid 32 Amniotic fluid 27220002 | Alpha-1-Fetoprotein measurement, 3.0 3.0 - Added by PITUS-16 project amniotic fluid | Alpha-fetoprotein tumour marker AFP 31 Serum; Plasma 441825001 | Measurement of alpha fetoprotein as 1.0 1.0 - Added by PUTS project marker for malignant neoplasm | Alpha-galactosidase 19 Plasma 77031000 | Alpha-galactosidase measurement | 3.0 3.0 - Added by PITUS-16 project Aluminium Al 9 Serum 273978001 | Serum aluminium measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Aluminium urine 15 Random urine 74817006 | Aluminium measurement, urine | 3.0 3.0 - Added by PITUS-16 project Aluminium urine 24h 19 24 hr urine 441778008 | Measurement of aluminium in 24 hour 3.0 3.0 - Added by PITUS-16 project urine specimen | Amikacin level 14 Serum 313536001 | Serum amikacin measurement | 2.0 3.0 - Changed preferred term from Amikacin 2.0 - Added by PITUS-14 Working group 2 Amikacin level CSF 18 CSF 766061000168109 | Amikacin measurement, CSF | 3.0 3.0 - Added by PITUS-16 project Amikacin level peak 19 Serum 442262008 | Measurement of amikacin peak 3.0 3.0 - Added by PITUS-16 project concentration | Amikacin level trough 21 Serum 442388009 | Measurement of amikacin trough 3.0 3.0 - Added by PITUS-16 project concentration | Amino acids AA 12 Plasma 313402005 | Plasma amino acid measurement | 1.0 1.0 - Added by PUTS project Amino acids urine Cystine 17 Urine 76503006 | Amino acids measurement, quantitative, 3.0 3.0 - Added by PITUS-16 project urine | Amiodarone level Amiodarone 16 Serum 166971003 | Serum amiodarone measurement | 3.0 3.0 - Added synonym 'Amiodarone' 1.0 - Added by PUTS project Amitriptyline 13 Serum 69652002 | Amitriptyline measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Ammonia NH3 7 Plasma 313952006 | Plasma ammonia measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Amoeba culture 14 Faeces 122194000 | Amoeba culture | 3.0 3.0 - Added by PITUS-16 project Amphetamine screen urine Amphetamine urine screen; drug screen; 25 Urine 314104009 | Urine amphetamine screening test | 2.0 2.0 - Added by PITUS-14 Working group 2 Amphetamine drug screen Amphetamine urine Urine Amphetamine RCPA QAP list only 17 Urine 269890008 | Urine amphetamine measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Amylase 7 Serum 89659001 | Amylase measurement, serum | 1.0 1.0 - Added by PUTS project Amylase isoenzymes 18 Serum 121327007 | Amylase isoenzyme measurement | 3.0 3.0 - Added by PITUS-16 project Amylase urine 13 Urine 28378007 | Amylase measurement, urine | 3.0 3.0 - Added by PITUS-16 project Amylase urine 24h 17 313515003 | 24 hour urine amylase output 3.0 3.0 - Added by PITUS-16 project measurement | Anabolic steroids 17 Urine 440691007 | Qualitative measurement of anabolic 3.0 3.0 - Added by PITUS-16 project steroid in urine | ANCA Antineutrophil cytoplasmic Ab 4 Serum 31709000 | Antineutrophil cytoplasmic antibody 3.0 3.0 - Added by PITUS-16 project measurement | Androstenedione 15 Serum 271224004 | Serum androstenedione measurement | 2.0 2.0 - Added by PITUS-14 Working group 2

Angiotensin converting enzyme ACE 30 Serum 166589006 | Serum angiotensin-converting enzyme 2.1 2.1 - Changed preferred term from 'Angiotensin Converting Enzyme' measurement | 2.0 - Added by PITUS-14 Working group 2

Anion gap A Gap RCPA QAP list only 9 Serum 271057005 | Serum anion gap measurement | 2.1 2.1 - Changed preferred term from ‘Anion Gap’ 2.0 - Added by PITUS-14 Working group 2

Page 2 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History Anthrax Ab Bacillus anthracis Ab; Anthrax antibodies; 10 Blood; Skin lesion 121931008 | Measurement of Bacillus anthracis 3.0 3.0 - Added by PITUS-16 project Bacillus anthracis antibodies; B. anthracis swab or aspirates; antibody | antibodies Spinal fluid; Respiratory secretions

Anthrax nucleic acid Anthrax PCR; Bacillus anthracis DNA; B. 20 Blood; Skin lesion 409613001 | Polymerase chain reaction for Bacillus 3.0 3.0 - Added by PITUS-16 project anthracis DNA; Anthrax; Bacillus anthracis swab or aspirates; anthracis | PCR; Bacillus anthracis nucleic acid Spinal fluid; Respiratory secretions

Anti factor Xa Anti Xa; LMWH; Low molecular weight 14 Plasma 250363000 | Anti factor Xa measurement | 3.0 3.0 - Added by PITUS-16 project heparin assay Anti immunoglobulin A Ab Anti IgA antibodies 24 Serum 359897007 | Anti-IgA assay | 3.0 3.0 - Added by PITUS-16 project Antibody screen Ab screen; Abs 15 Serum; Plasma 252315008 | Blood group antibody screening | 1.0 1.0 - Added by PUTS project Anti-D titre 12 Blood 103968008 | Anti-D titration | 2.1 2.1 - Changed preferred term from 'Anti-D Titre' 2.0 - Added by PITUS-14 Working group 2 Anti-deoxyribonuclease B Ab Anti-DNase B antibodies 27 Serum 394723001 | Anti-DNAse B antibody level | 3.0 3.0 - Added by PITUS-16 project Antidiuretic hormone ADH 20 Plasma 61966007 | Antidiuretic hormone measurement | 3.0 3.0 - Added by PITUS-16 project Antimony Sb 8 Serum; Plasma 824261000168101 | Serum antimony measurement | 3.0 3.0 - Added by PITUS-16 project

Antimony urine 14 Urine 12712006 | Antimony measurement, urine | 3.0 3.0 - Added by PITUS-16 project Anti-Mullerian hormone AMH; Mullerian-inhibiting hormone; MIH; 22 Serum 711358004 | Measurement of anti-Mullerian hormone, 3.0 3.0 - Added by PITUS-16 project Mullerian inhibiting factor; MIF; Mullerian- quantitative | inhibiting substance; MIS Antinuclear Ab ANA; ANF; Nuclear Ab; Antinuclear factor 14 Serum 359788000 | ANA measurement | 1.0 1.0 - Added by PUTS project

Antiphospholipid Ab Antiphospholipid antibodies; APL antibodies; 19 82886000 | Antiphospholipid antibody measurement | 3.0 3.0 - Added by PITUS-16 project APS antibodies Antistreptolysin O titre ASOT titre 24 Serum 275738004 | ASO titre test | 3.0 3.0 - Added by PITUS-16 project Antithrombin AT III 12 Plasma 36288005 | Antithrombin III assay | 2.0 2.0 - Added by PITUS-14 Working group 2 APC resistance 14 Plasma 41833004 | Activated protein C resistance assay | 2.0 2.0 - Added by PITUS-14 Working group 2 Apolipoprotein A-I Lipoprotein A1; LPA1; Apo A1 18 Serum 443309005 | Measurement of apolipoprotein A-I | 3.0 3.0 - Added synonym 'Apo A1' 2.0 - Added by PITUS-14 Working group 2 Apolipoprotein B Apo B; Lipoprotein B; LPB 16 Serum 104531005 | Apolipoproteins B measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Apolipoprotein E genotyping Apo E genotyping 27 Serum 412985006 | Apolipoprotein E genotype determination 3.0 3.0 - Added by PITUS-16 project | APTT Activated partial thromboplastin time 4 Plasma 42525009 | Partial thromboplastin time, activated | 1.0 1.0 - Added by PUTS project

Aquaporin-4 Ab Anti aquaporin-4; anti-NMO; Neuromyelitis 14 445434008 | Measurement of aquaporin-4 antibody | 3.0 3.0 - Added by PITUS-16 project optica Ab; NMO-ig Arbovirus nucleic acid Arbovirus PCR; Sindbis virus nucleic acid; 22 Serum 832741000168101 | Arbovirus nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project Sindbis virus PCR Arbovirus serology Arbovirus antibodies; Sindbis virus Ab; 18 Serum 838311000168104 | Arbovirus antibody measurement 3.0 3.0 - Added by PITUS-16 project Sindbis virus antibodies | Arsenic As 8 Whole blood 45074006 | Arsenic measurement, blood | 2.0 2.0 - Added by PITUS-14 Working group 2 Arsenic hair As hair 12 Hair 28811004 | Arsenic measurement, hair | 3.0 3.0 - Added by PITUS-16 project Arsenic nails As nails 13 Nails 83904006 | Arsenic measurement, nails | 3.0 3.0 - Added by PITUS-16 project Arsenic urine Urine Arsenic; Urine As 13 Urine 90690006 | Arsenic measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Arsenic urine 24h Arsenic 24 hour urine; 24 hr urine Arsenic; 17 24 hr urine 391357007 | 24 hour urine arsenic output | 3.0 3.0 - Changed preferred term from 'Arsenic 24 hr urine' 24 hr urine As 2.0 - Added by PITUS-14 Working group 2 Aspartate aminotransaminase AST; AST; Aspartate transaminase; Glutamic 27 Serum 250641004 | AST serum measurement | 1.0 1.0 - Added by PUTS project oxaloacetic transaminase; SGOT

Aspergillus serology Aspergillus precipitins 20 87407009 | Serologic test for Aspergillus | 1.0 1.0 - Added by PUTS project Astrovirus nucleic acid Astrovirus PCR 23 122298005 | Astrovirus RNA assay | 3.0 3.0 - Added by PITUS-16 project Atypical mycobacteria Mycobacterium PCR 21 Sputum 122285001 | Mycobacterium identification | 2.0 2.0 - Added by PITUS-14 Working group 2 Avian influenza Ab Avian influenza antibodies 18 117865004 | Measurement of avian influenza A virus 3.0 3.0 - Added by PITUS-16 project antibody | Avian influenza nucleic acid Avian influenza PCR 28 445346006 | Detection of avian influenza A using 3.0 3.0 - Added by PITUS-16 project polymerase chain reaction technique | Avian precipitins Avian precipitins IgG specific 17 315070009 | Avian precipitin test | 3.0 3.0 - Added by PITUS-16 project Barmah Forest virus Ab BFV Ab; BF Ab; Barmah Forest virus serology; 22 Serum 443388000 | Measurement of Barmah Forest virus 3.0 3.0 - Added synonym 'Arbovirus antibody' Arbovirus antibody antibody | 1.0 - Added by PUTS project Barmah Forest virus nucleic acid Arbovirus nucleic acid 32 766121000168103 | Barmah Forest virus nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | BCR-ABL bcr-abl for ALL; bcr-abl for CML 7 444157002 | Detection of BCR-ABL translocation | 2.0 2.0 - Added by PITUS-14 Working group 2 Bence Jones protein Protein electrophoresis urine; Urine EPG 19 Urine 443363008 | Measurement of Bence Jones protein | 1.0 1.0 - Added by PUTS project

Beryllium urine 15 443976009 | Quantitative measurement of beryllium 3.0 3.0 - Added by PITUS-16 project in urine specimen | Beta HCG quantitation BHCG Titre; Human Chorionic Gonadotropin 21 Serum; Plasma 67900009 | Human chorionic gonadotropin 3.0 3.0 - Added synonyms 'hCG' and 'hCG quantitative' Quantitative; QHCG; hCG; hCG quantitative measurement | 1.0 - Added by PUTS project

Beta-2- transferrin Request for CSF leak 19 Body fluid 121742007 | beta-2-Transferrin measurement | 3.0 3.0 - Added by PITUS-16 project Beta-2-glycoprotein Ab Anti B2 glycoprotein 1 IgG antibody; B2GP1; 22 Serum 413001005 | Anti B2 glycoprotein 1 IgG antibody 3.0 3.0 - Changed preferred term from 'Beta-2-glycoprotein'; added B2-GPI; B2-GP1; B2GP measurement | synonyms 2.1 - Changed preferred term from 'Beta-2-Glycoprotein' 2.0 - Added by PITUS-14 Working group 2 Beta-2-glycoprotein IgM B2GPI IgM 23 Serum 413003008 | Anti B2 glycoprotein 1 IgM antibody 3.0 3.0 - Added by PITUS-16 project measurement | Beta-2-microglobulin B2MG; B2M; B2Microglobulin 20 Serum 166587008 | Serum beta 2 microglobulin 2.0 2.0 - Added by PITUS-14 Working group 2 measurement | Bicarbonate Bicarb; Carbon dioxide; HCO3; Total 11 Serum 271239003 | Serum bicarbonate measurement | 1.0 1.0 - Added by PUTS project bicarbonate Bilirubin Total bilirubin; Bilirubin total; SBR; Bili 10 Serum 313840000 | Serum total bilirubin measurement | 1.0 1.0 - Added by PUTS project Bilirubin amniotic fluid 24 Amniotic fluid 359990005 | Bilirubin measurement, amniotic fluid | 3.0 3.0 - Added by PITUS-16 project

Bilirubin conjugated Bili-C; Bilirubin direct; Bili-D; Conjugated 20 Serum 313856005 | Serum conjugated bilirubin measurement 1.0 1.0 - Added by PUTS project bilirubin | Bilirubin CSF Xanthochromia 14 CSF 737671000168103 | Bilirubin measurement, CSF | 3.0 3.0 - Added by PITUS-16 project Bilirubin neonatal SBR neonatal; Neonatal bilirubin 18 Serum; Plasma 417567002 | Bilirubin, neonatal measurement | 1.0 1.0 - Added by PUTS project Bisacodyl level Bisacodil 15 Urine 391346002 | Urine bisacodyl level | 3.0 3.0 - Added by PITUS-16 project Bismuth 7 Serum 443975008 | Quantitative measurement of mass 3.0 3.0 - Added by PITUS-16 project concentration of bismuth in serum or plasma | Bismuth urine 13 Urine 443834000 | Quantitative measurement of bismuth in 3.0 3.0 - Added by PITUS-16 project urine specimen | Bismuth whole blood 19 Whole Blood 64685008 | Bismuth measurement | 3.0 3.0 - Added by PITUS-16 project Bleeding time BT; Duke bleeding time; Ivy bleeding time 13 72406003 | Bleeding time | 3.0 3.0 - Added by PITUS-16 project

Blood culture Culture blood; BC 13 30088009 | Blood culture | 1.0 1.0 - Added by PUTS project Blood film Peripheral smear; Film; BF 10 Whole blood 14768001 | Peripheral blood smear interpretation | 1.0 1.0 - Added by PUTS project

Blood gas arterial Arterial blood gas; ABG 18 Arterial blood 91308007 | Blood gases, arterial measurement | 1.0 1.0 - Added by PUTS project Blood gas arterial cord blood 29 444043002 | Measurement of blood gases in arterial 3.0 3.0 - Added by PITUS-16 project cord blood | Blood gas capillary 19 10812009 | Blood gases, capillary measurement | 3.0 3.0 - Added by PITUS-16 project Blood gas mixed venous blood 28 447414006 | Measurement of blood gases in mixed 3.0 3.0 - Added by PITUS-16 project venous blood specimen | Blood gas scalp blood 21 832501000168108 | Fetal scalp blood gases 3.0 3.0 - Added by PITUS-16 project measurement | Blood gas venous VBG; Gases 16 Venous blood 61911006 | Blood gases, venous measurement | 1.0 1.0 - Added by PUTS project Blood gas venous cord blood 27 443966006 | Measurement of blood gases in venous 3.0 3.0 - Added by PITUS-16 project cord blood | Blood group Blood group typing; BG; ABO subgroup; 11 Blood 103872006 | Blood group typing, RH phenotyping | 3.0 3.0 - Added synonym 'Antenatal screen' Antenatal screen 1.0 - Added by PUTS project Blood group and antibody screen Group and antibodies; ABO & Abs; G & Abs; 31 Serum; Plasma 20099001 | Blood typing, ABO, Rho(D) and RBC 3.0 3.0 - Added synonyms 'Antenatal screen' and 'Group & Ab screen' GRP; GRP and Screen; Antenatal screen; antibody screening | 1.0 - Added by PUTS project Group & Ab screen Bone marrow biopsy BM biopsy 18 Bone marrow 56241004 | Bone marrow biopsy, needle or trocar | 3.0 3.0 - Added by PITUS-16 project

Bordetella pertussis Ab Bordetella pertussis serology; Pertussis Ab 23 Serum 121942004 | Measurement of Bordetella pertussis 1.0 1.0 - Added by PUTS project antibody | Bordetella pertussis culture 28 122206002 | Bordetella pertussis culture | 3.0 3.0 - Added by PITUS-16 project Bordetella pertussis nucleic acid Bordetella pertusis PCR; Bordetella pertussis 34 Nasopharyngeal 766081000168100 | Bordetella pertussis nucleic acid 3.0 3.0 - Added by PITUS-16 project detection aspirate or swab assay | Borrelia burgdorferi Ab Borrelia burgdorferi antibodies 23 Serum 104277002 | Measurement of Borrelia burgdorferi 3.0 3.0 - Added by PITUS-16 project antibody | Borrelia burgdorferi culture 28 122270007 | Borrelia burgdorferi culture | 3.0 3.0 - Added by PITUS-16 project Borrelia burgdorferi nucleic acid 33 398352008 | Borrelia burgdorferi nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project

Bromide level 13 Serum 828421000168103 | Serum bromide measurement | 3.0 3.0 - Added by PITUS-16 project

Bromide level urine 19 Urine 75041001 | Bromides measurement, urine | 3.0 3.0 - Added by PITUS-16 project

Page 3 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History Brucella Ab Brucella serology; Brucella abortus; Brucella 11 Serum 134445001 | Brucella antibody level | 2.0 2.0 - Added by PITUS-14 Working group 2 suis; Brucella melitensis Brucella nucleic acid Brucella PCR 21 832511000168106 | Brucella species nucleic acid assay 3.0 3.0 - Added by PITUS-16 project | B-Type natriuretic peptide BNP 26 Serum 390917008 | Brain natriuretic peptide measurement | 2.1 2.1 - Changed preferred term from 'B-Type Natriuretic Peptide' 2.0 - Added by PITUS-14 Working group 2

Burkholderia mallei nucleic acid Burkholderia mallei PCR; Glanders 32 832521000168104 | Burkholderia mallei nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | Burkholderia pseudomallei Ab Burkholderia pseudomallei antibodies 28 Serum 766071000168103 | Measurement of Burkholderia 3.0 3.0 - Added by PITUS-16 project pseudomallei antibody | Burkholderia pseudomallei culture 33 767051000168109 | Burkholderia pseudomallei 3.0 3.0 - Added by PITUS-16 project culture | Burkholderia pseudomallei nucleic acid Burkholderia pseudomallei PCR 38 766811000168101 | Burkholderia pseudomallei nucleic 3.0 3.0 - Added by PITUS-16 project acid assay | C peptide Insulin C-peptide 9 Serum; Plasma 88705004 | Insulin C-peptide measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 C1 esterase inhibitor C1q esterase inhibitor assay; complement C1 21 Serum 104361001 | Complement C1 esterase inhibitor, total 2.0 2.0 - Added by PITUS-14 Working group 2 esterase inhibitor; C1-Inhibitor measurement |

C3 nephritic factor C3 NeF 19 Serum 313692006 | Complement component 3 nephritic 3.0 3.0 - Added by PITUS-16 project factor measurement | CA 125 Cancer Antigen 125 6 Serum 80529009 | CA 125 measurement | 1.0 1.0 - Added by PUTS project CA 15-3 Cancer antigen 15-3 7 Serum 113058009 | CA 15-3 measurement | 1.0 1.0 - Added by PUTS project CA 19-9 Cancer antigen 19-9 7 Serum 40939009 | Cancer antigen 19-9 measurement | 1.0 1.0 - Added by PUTS project Cadmium urine Urine Cadmium 13 Urine 81341007 | Cadmium measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Cadmium urine 24h Cadmium 24 hour urine; 24 hr urine 17 24 hr urine 441488005 | Measurement of cadmium in 24 hour 3.0 3.0 - Changed preferred term from 'Cadmium 24 hr urine' Cadmium; 24 hr urine Cd urine specimen | 2.0 - Added by PITUS-14 Working group 2 Cadmium whole blood Cd 19 Whole blood 313554002 | Blood cadmium measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Caeruloplasmin 14 Serum 87365002 | Caeruloplasmin measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Caffeine 8 Serum 37999005 | Caffeine measurement | 3.0 3.0 - Added by PITUS-16 project Calcitonin 10 Serum 3025001 | Calcitonin measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Calcium Ca 7 Serum 271240001 | Serum calcium measurement | 2.0 2.0 - Fixed. Pipe was missing from the Mapped term 1.0 - Added by PUTS project. Calcium fluid Fluid Calcium 13 Fluid 391355004 | Fluid sample calcium level | 2.0 2.0 - Added by PITUS-14 Working group 2 Calcium ionised Ionised calcium 15 Serum 391084000 | Serum ionised calcium measurement | 1.0 1.0 - Added by PUTS project

Calcium Magnesium Phosphate CMP panel; Ca Mg PO4 27 Serum 828431000168100 | Total serum calcium, magnesium 3.0 3.0 - Added by PITUS-16 project and phosphate measurement | Calcium urine Urine Calcium 13 Urine 73668004 | Calcium measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Calcium urine 24h Ca 24 hour urine; Total Calcium - 24 hour 17 24 hr urine 313492004 | 24 hour urine calcium output 3.0 3.0 - Changed preferred term from 'Calcium 24 hr urine' urine; 24 hr Urine Calcium; Calcium 24 hour measurement | 2.0 - Added by PITUS-14 Working group 2 urine Calculi biliary tract Calculi - biliary; Gallstone analysis 21 27375007 | Gallstone analysis | 3.0 3.0 - Added by PITUS-16 project Calculi urinary tract Calculus analysis; Kidney stone analysis; 21 16620001 | Kidney stone analysis | 3.0 3.0 - Added by PITUS-16 project Urinary stone analysis Calprotectin faeces Faecal calprotectin; Stool Calprotectin; 19 Faeces 444006004 | Quantitative measurement of 3.0 3.0 - Added by PITUS-16 project Faeces calprotectin calprotectin in stool specimen | Campylobacter Ab Campylobacter antibodies 16 Serum 104280001 | Measurement of Campylobacter species 3.0 3.0 - Added by PITUS-16 project antibody | Campylobacter culture 21 122253004 | Campylobacter species culture | 3.0 3.0 - Added by PITUS-16 project Cannabinoid urine quanitative Cannabis metabolite level 29 442471001 | Quantitative measurement of 3.0 3.0 - Added by PITUS-16 project cannabinoids | Cannabinoid urine screen Cannabis metabolite qualitative 24 Urine 314082007 | Urine cannabinoids screening test | 3.0 3.0 - Added by PITUS-16 project Carbamazepine free Tegretol free 18 439380003 | Measurement of free carbamazepine | 3.0 3.0 - Added by PITUS-16 project

Carbamazepine level Tegretol 19 Serum 269869000 | Serum carbamazepine measurement | 1.0 1.0 - Added by PUTS project

Carbohydrate-deficient transferrin 34 Serum 121275000 | Carbohydrate deficient transferrin 3.0 3.0 - Added by PITUS-16 project measurement | Carboxyhaemoglobin COHb; Carbon Monoxide 18 Whole blood 19821003 | Carboxyhaemoglobin measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Carcinoembryonic Ag CEA 19 Serum/Plasma 60267001 | Carcinoembryonic antigen measurement | 1.0 1.0 - Added by PUTS project

Cardiac markers 15 391485008 | Cardiac markers | 1.0 1.0 - Added by PUTS project Cardiolipin Ab ACA; Cardiolipin Ab; ACL Ab; aCl Ab 14 Serum 65946008 | Anticardiolipin antibody measurement | 3.0 3.0 - Added synonyns 'Cardiolipin Ab; ACL Ab; aCl Ab' 1.0 - Added by PUTS project Carnitine 9 Serum; Plasma 36174000 | Carnitine measurement | 3.0 3.0 - Added by PITUS-16 project Carotene Beta carotene 8 Serum 28805002 | Carotene measurement | 3.0 3.0 - Added by PITUS-16 project Cat scratch disease Ab Cat scratch disease antibodies 22 Serum 315093003 | Cat scratch fever antibody level | 3.0 3.0 - Added by PITUS-16 project Catecholamines urine 20 Urine 90231002 | Catecholamines, fractionation 3.0 3.0 - Added by PITUS-16 project measurement, urine | CD34 CD34 count; Total CD34 4 Whole Blood 313505009 | CD34 stem cell count procedure | 3.0 3.0 - Added by PITUS-16 project CD4 and CD19 count T & B cells subsets; T cells subsets; B cells 18 3450007 | Lymphocytes, T & B cell evaluation | 3.0 3.0 - Added by PITUS-16 project subsets CD4 and CD8 T cells subsets; CD4; CD8 11 Whole Blood 413785007 | Count of cells positive for CD3 antigen 3.0 3.0 - Added by PITUS-16 project and CD4 antigen and CD8 antigen | Centromere Ab Centromere antibodies; Anticentromere 13 Serum 43872009 | Antibody to centromere measurement | 3.0 3.0 - Added by PITUS-16 project antibodies; ACA Cerebrospinal fluid examination CSF 31 CSF 167699000 | Cerebrospinal fluid examination | 3.0 3.0 - Added by PITUS-16 project Chikungunya virus Ab Chikungunya virus antibody; Chikungunya 20 Serum 443346009 | Measurement of Chikungunya virus 3.0 3.0 - Added by PITUS-16 project Ab; Arbovirus antibody antibody | Chikungunya virus nucleic acid Arbovirus nucleic acid 30 766041000168105 | Chikungunya virus nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | Chlamydia Ab Chlamydia antibodies 12 Serum 104281002 | Measurement of Chlamydia antibody | 3.0 3.0 - Added by PITUS-16 project

Chlamydia pneumoniae Ab 23 Serum 121953005 | Measurement of Chlamydia pneumoniae 2.0 2.0 - Added by PITUS-14 Working group 2 antibody | Chlamydia pneumoniae Ag Chlamydia pneumoniae antigen; Bacterial 23 Serum 121954004 | Chlamydia pneumoniae antigen assay | 3.0 3.0 - Added synonym 'Bacterial antigen' antigen 2.0 - Added by PITUS-14 Working group 2 Chlamydia psittaci Ab Chlamydia psittaci antibodies; Ornithosis; 21 Serum 121955003 | Measurement of Chlamydia psittaci 3.0 3.0 - Added by PITUS-16 project Psittacosis antibody | Chlamydia psittaci nucleic acid Chlamydia psittaci PCR; Psittacosis 31 767791000168102 | Chlamydia psittaci nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | Chlamydia trachomatis Ab 24 121957006 | Measurement of Chlamydia trachomatis 3.0 3.0 - Added by PITUS-16 project antibody | Chlamydia trachomatis nucleic acid Chlamydia PCR; C trachomatis PCR; C 35 398452009 | Chlamydia trachomatis nucleic acid assay 3.0 3.0 - Added synonyms 'Chlamydia trachomatis screen; Chlamydia trachomatis NAT; C trachomatis DNA; | trachomatis PCR' Chlamydia trachomatis screen; Chlamydia 1.0 - Added by PUTS project trachomatis PCR Chloride Cl 8 Serum 271238006 | Serum chloride measurement | 1.0 1.0 - Added by PUTS project Chloride sweat Cystic fibrosis sweat test 14 Sweat 86964003 | Cystic fibrosis sweat test | 3.0 3.0 - Added by PITUS-16 project Chloride urine Urine Chloride; Urine Cl 14 Urine 14663000 | Chloride measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Chloride urine 24h Chloride 24 hour urine; 24 hr urine Chloride; 18 24 hr urine 412804007 | 24 hour urine chloride output | 3.0 3.0 - Changed preferred term from 'Chloride 24 hr urine' 24 hr urine Cl 2.0 - Added by PITUS-14 Working group 2 Cholesterol Total cholesterol; TC; Chol 11 Serum 412808005 | Serum total cholesterol measurement | 1.0 1.0 - Added by PUTS project

Cholesterol Triglycerides TC TG; Chols and Trigs 25 Serum 443915001 | Measurement of total cholesterol and 1.0 1.0 - Added by PUTS project triglycerides | Cholinesterase 14 Serum 390763009 | Cholinesterase measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Cholinesterase amniotic fluid 29 Amniotic fluid 36478006 | Acetylcholinesterase measurement, 3.0 3.0 - Added by PITUS-16 project amniotic fluid | Cholinesterase red cell Acetylcholinesterase, red blood cell; 23 46190003 | Acetylcholinesterase, red blood cell 3.0 3.0 - Added by PITUS-16 project Cholinesterase, erythrocytes measurement | Chromium 8 Serum 391566007 | Serum chromium level | 2.0 2.0 - Added by PITUS-14 Working group 2 Chromium urine Urine Chromium 14 Urine 78310005 | Chromium measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Chromium urine 24h Chromium 24 hour urine; 24 hr urine 18 24 hr urine 444125003 | Quantitative measurement of ratio of 3.0 3.0 - Changed preferred term from 'Chromium 24 hr urine' Chromium; 24 hr urine Cr chromium to creatinine in 24 hour urine | 2.0 - Added by PITUS-14 Working group 2 Chromium whole blood Whole blood Chromium 20 Whole blood 443934001 | Quantitative measurement of mass 2.0 2.0 - Added by PITUS-14 Working group 2 concentration of chromium in peripheral blood | Chromosome studies Cytogenetics 19 395113006 | Chromosome studies | 1.0 1.0 - Added by PUTS project Chymotrypsin faeces Faecal chymotrypsin 19 Faeces 313615009 | Faecal chymotrypsin measurement | 3.0 3.0 - Added by PITUS-16 project CKMB CK isoenzyme MB 4 104613001 | Creatine kinase MB measurement | 1.0 1.0 - Added by PUTS project Clonazepam level 16 Serum; Plasma 7932007 | Clonazepam measurement | 3.0 3.0 - Added by PITUS-16 project Clostridium botulinum toxin C. botulinum toxin; Botulism toxin 27 Serum; Faeces; 121962007 | Clostridium botulinum toxin identification 3.0 3.0 - Added by PITUS-16 project Pus; Tissue; Food |

Clostridium difficile Ag Bacterial antigen 24 118114008 | Clostridium difficile antigen assay | 3.0 3.0 - Added synonym 'Bacterial antigen' 1.0 - Added by PUTS project Clostridium difficile culture 29 Faeces 122209009 | Clostridium difficile culture | 2.0 2.0 - Added by PITUS-14 Working group 2 Clostridium difficile detection 31 121897008 | Clostridium difficile detection | 3.0 3.0 - Added by PITUS-16 project Clostridium difficile nucleic acid Clostridium difficile PCR; C. difficile PCR 34 767251000168101 | Clostridium difficile nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | Clostridium difficile toxin C Difficile Toxin; C Diff Toxin 27 Faeces 413047002 | Clostridium difficile toxin detection | 2.0 2.0 - Added by PITUS-14 Working group 2

Clostridium perfringens toxin C. perfringens; Epsilon toxin 29 121965009 | Clostridium perfringens enterotoxin assay 3.0 3.0 - Added by PITUS-16 project | Clozapine Clozaril; Norclozapine 9 Serum 105140007 | Clozapine measurement | 2.0 2.0 - Added by PITUS-14 Working group 2

Page 4 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History Coagulation profile Coagulation panel; Coagulation studies; 19 Plasma 3116009 | Blood coagulation panel | 1.0 1.0 - Added by PUTS project Clotting profile; Clotting studies; Clotting panel; Coags Cobalt Co 6 Serum 105141006 | Cobalt measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Cobalt urine Urine Cobalt; Urine Co 12 Urine 428261001 | Measurement of cobalt/creatinine ratio | 2.0 2.0 - Added by PITUS-14 Working group 2

Cobalt whole blood Whole blood Cobalt; Whole blood Co 18 Whole blood 441883005 | Measurement of cobalt in blood 2.0 2.0 - Added by PITUS-14 Working group 2 specimen | Codeine level 13 Serum 105142004 | Codeine measurement | 3.0 3.0 - Added by PITUS-16 project Cold agglutinins Cold agglutinins level; Cold agglutinins titre 16 Serum 47889002 | Cold agglutinin measurement | 3.0 3.0 - Added by PITUS-16 project

Collagen binding assay CBA 22 Plasma 408278000 | von Willebrand factor collagen binding 3.0 3.0 - Added by PITUS-16 project assay | Collagen crosslinked C-telopeptide Collagen crosslink fragments; s-βCTX; CTX 34 Serum 826511000168107 | Serum collagen crosslinked C- 3.0 3.0 - Added by PITUS-16 project telopeptide measurement | Complement CH50 Complement CH100; Total haemolytic 15 Serum 104355004 | Complement C4 CH50 measurement | 3.0 3.0 - Added by PITUS-16 project complement Complement component 3 C3 22 Serum 43992003 | C>3< complement assay | 2.0 2.0 - Added by PITUS-14 Working group 2 Complement component 4 C4 22 Serum 31483002 | C>4< complement assay | 2.0 2.0 - Added by PITUS-14 Working group 2 Complement components C1q C1q 25 Serum 49204009 | C>12< complement assay | 3.0 3.0 - Added by PITUS-16 project Complement components C5 C5 24 Serum 33189000 | C>5< complement assay | 3.0 3.0 - Added by PITUS-16 project Complement components C6 C6 24 Serum 18706007 | C>6< complement assay | 3.0 3.0 - Added by PITUS-16 project Complement components C7 C7 24 Serum 55283000 | C>7< complement assay | 3.0 3.0 - Added by PITUS-16 project Complement components C8 C8 24 Serum 70389001 | C>8< complement assay | 3.0 3.0 - Added by PITUS-16 project Complement components C9 C9 24 Serum 37479007 | C>9< complement assay | 3.0 3.0 - Added by PITUS-16 project Conjunctiva culture Conjunctival swab/fluid 19 Conjunctival swab; 419834003 | Culture of conjunctiva | 3.0 3.0 - Added by PITUS-16 project Conjunctival fluid

Copper Cu 6 Serum 85554007 | Copper measurement, serum | 2.0 2.0 - Added by PITUS-14 Working group 2 Copper urine Urine Copper; Urine Cu 12 Urine 76693007 | Copper measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Copper urine 24h Copper 24 hour urine; 24 hr urine Copper; 24 16 24 hr urine 313934006 | 24 hour urine copper output 3.0 3.0 - Changed preferred term from 'Copper 24 hr urine' hr urine Cu measurement | 2.0 - Added by PITUS-14 Working group 2 Copper whole blood Whole blood Copper; Whole blood Cu 18 Whole blood 271287008 | Blood copper measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Cornea culture 14 419592009 | Culture of cornea | 3.0 3.0 - Added by PITUS-16 project Corneal biopsy 14 44716001 | Biopsy of cornea | 3.0 3.0 - Added by PITUS-16 project Corneal scrapings 17 Corneal scraping; 418736004 | Scraping of cornea | 3.0 3.0 - Added by PITUS-16 project Corneal biopsy

Corrected calcium Adjusted Calcium; Corrected Ca; Adjusted Ca 17 Serum 166708003 | Corrected serum calcium measurement | 2.0 2.0 - Added by PITUS-14 Working group 2

Cortisol 8 Serum 271535005 | Serum cortisol measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Cortisol saliva Salivary cortisol 15 Saliva 443984008 | Quantitative measurement of 3.0 3.0 - Added by PITUS-16 project hydrocortisone in saliva specimen | Cortisol urine Urine Cortisol 14 Urine 391387001 | Urine cortisol level | 2.0 2.0 - Added by PITUS-14 Working group 2 Cortisol urine 24h Cortisol 24 hour urine; 24 hr urine Cortisol 18 24 hr urine 313516002 | 24 hour urine cortisol output 3.0 3.0 - Changed preferred term from 'Cortisol 24 hr urine' measurement | 2.0 - Added by PITUS-14 Working group 2 Cotinine urine Nicotine urine 14 Urine 313776008 | Urine cotinine measurement | 3.0 3.0 - Added by PITUS-16 project C-reactive protein CRP 18 Serum 55235003 | C-reactive protein measurement | 3.0 3.0 - Cahnged preferred term from 'C-Reactive protein' 1.0 - Added by PUTS project C-reactive protein high sensitivity CRP HS; HS CRP; High-sensitive CRP; Ultra- 35 Serum 711357009 | Measurement of C-reactive protein using 3.0 3.0 - Added by PITUS-16 project sensitive CRP high sensitivity technique | Creatine kinase CK; Creatine phosphokinase; CPK 15 Serum 398245009 | Serum creatine kinase measurement | 1.0 1.0 - Added by PUTS project

Creatine kinase isoenzymes Creatine kinase isoforms 26 Serum; Plasma 16614002 | Creatine kinase isoenzymes measurement 3.0 3.0 - Added by PITUS-16 project |

Creatine kinase MB index Creatine kinase MB isoenzymes 24 Serum 250736004 | Creatine kinase MB isoenzyme/total 3.0 3.0 - Added by PITUS-16 project creatine kinase ratio measurement | Creatinine Creat 10 Serum 113075003 | Creatinine measurement, serum | 1.0 1.0 - Added by PUTS project Creatinine clearance Cr Clearance 20 Serum 395680003 | Estimated creatine clearance | 2.0 2.0 - Added by PITUS-14 Working group 2 Creatinine clearance Cockcroft and Gault Cr Clearance Cockcroft and Gault 40 442407001 | Estimation of creatinine clearance by 3.0 3.0 - Added by PITUS-16 project Cockcroft-Gault formula | Creatinine clearance urine 24h Creatinine clearance 24 hour urine; 24 hr 30 24 hr urine 167181009 | Measurement of renal clearance of 3.0 3.0 - Changed preferred term from 'Creatinine clearance 24 hr urine Creatinine clearance; Creatinine creatinine | urine' clearance 2.0 - Added by PITUS-14 Working group 2 Creatinine urine Urine creatinine 16 Urine 271260009 | Creatinine measurement, urine | 1.0 1.0 - Added by PUTS project Creatinine urine 24h Creatinine 24 hour urine; 24 hr urine 20 24 hr urine 8879006 | Creatinine measurement, 24 hour urine | 3.0 3.0 - Changed preferred term from 'Creatinine 24 hr urine' Creatinine 2.0 - Added by PITUS-14 Working group 2 Crossmatch Compatibility test; Xmatch; CXM; Xm 10 Blood 250404007 | Blood compatibility test | 1.0 1.0 - Added by PUTS project Cryoglobulin 12 Serum 31193002 | Cryoglobulin measurement | 3.0 3.0 - Added by PITUS-16 project Cryptococcal Ag Bacterial antigen 15 Serum; Blood 315107005 | Cryptococcus antigen level | 3.0 3.0 - Added synonym 'Bacterial antigen' 2.0 - Added by PITUS-14 Working group 2 Cryptosporidium Ag Cryptosporidium EIA 18 121981004 | Cryptosporidium species antigen assay | 3.0 3.0 - Added by PITUS-16 project

Cryptosporidium nucleic acid Cryptosporidium PCR 28 832531000168101 | Cryptosporidium nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | Culture Varicella zoster virus VZV culture 30 122202000 | Varicella virus culture | 1.0 1.0 - Added by PUTS project Cyclic adenosine monophosphate urine Cyclic AMP 36 Urine 52485003 | Cyclic adenosine monophosphate 3.0 3.0 - Added by PITUS-16 project measurement | Cyclic citrullinated peptide Ab CCP Ab 31 Urine 408200008 | Anti-cyclic citrullinated peptide antibody 1.0 1.0 - Added by PUTS project level | Cyclosporin Cyclosporin measurement 11 Whole blood 313656007 | Blood cyclosporin measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Cyclosporin 2h Cyclosporin 2 hr 14 442362006 | Measurement of ciclosporin 2 hours after 3.0 3.0 - Added by PITUS-16 project dosing | Cyclosporin trough 18 Serum 442494000 | Measurement of ciclosporin trough 3.0 3.0 - Added by PITUS-16 project concentration | Cystatin C 10 Serum; Plasma 408650007| Serum cystatin C measurement | 3.0 3.0 - Added by PITUS-16 project Cytology non gynae Cytology general 18 88242007 | Cytopathology procedure, preparation, 1.0 1.0 - Added by PUTS project screening and interpretation, nongenital source |

Cytomegalovirus Ab Cytomegalovirus serology; CMV Ab, CMV 18 Serum 30200007 | Cytomegalovirus antibody measurement | 1.0 1.0 - Added by PUTS project serology Cytomegalovirus Ab CMV antibody; CMV serology 18 Serum 252410004 | Cytomegalovirus antibody screening | 3.0 3.0 - Added by PITUS-16 project

Cytomegalovirus culture 23 122211000 | Cytomegalovirus culture | 3.0 3.0 - Added by PITUS-16 project Cytomegalovirus nucleic acid CMV nucleic acid amplification; CMV PCR 28 398568001 | Cytomegalovirus nucleic acid assay | 3.0 3.0 - Changed preferred term from 'CMV nucleic acid amplification' 2.0 - Added by PITUS-14 Working group 2

D-dimer FDP; Fibrinogen degredation products 7 Platelet poor 70648006 | D-dimer assay | 3.0 3.0 - Changed preferred name from 'D Dimer' plasma 1.0 - Added by PUTS project Dengue virus Ab Dengue virus serology; Dengue Ab; Arbovirus 15 Serum 121993008 | Measurement of Dengue virus antibody | 3.0 3.0 - Added synonyms 'Arbovirus antibody' and 'Dengue Ab' antibody 1.0 - Added by PUTS project Dengue virus Ag 15 122176006 | Dengue virus antigen assay | 3.0 3.0 - Added by PITUS-16 project Dengue virus nucleic acid Arbovirus nucleic acid 25 398560008 | Dengue nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project Desipramine level 17 Serum 113085002 | Desipramine measurement | 3.0 3.0 - Added by PITUS-16 project Dexamethasone suppression test DST 30 252190006 | Dexamethasone suppression test | 1.0 1.0 - Added by PUTS project DHEA sulphate DHEAS 13 Serum; Plasma 104624004 | Dehydroepiandrosterone measurement | 2.1 2.1 - Changed preferred term from 'DHEA Sulphate' 2.0 - Added by PITUS-14 Working group 2 Digoxin level Dig; Digoxin 13 Serum 269872007 | Serum digoxin measurement | 3.0 3.0 - Added synonym 'Digoxin' 1.0 - Added by PUTS project Dihydrotestosterone DHT 19 Serum; Plasma 413993002 | Dihydrotestosterone level | 2.0 2.0 - Added by PITUS-14 Working group 2 Direct antiglobulin test DAT; Coombs direct; Direct coombs test 24 Blood 77020008 | Direct Coombs test | 1.0 1.0 - Added by PUTS project Disopyramide 12 Serum 70404008 | Disopyramide measurement | 3.0 3.0 - Added by PITUS-16 project D-lactate 9 Serum 425954005 | D-lactate measurement | 3.0 3.0 - Added by PITUS-16 project DNA Ab Deoxyribonuclease souble-stranded Ab; Anti- 6 87978006 | Antibody to double stranded DNA 1.0 1.0 - Added by PUTS project dsDNA Ab measurement | DNA ploidy DNA analysis flow cytometry; Plasma cell 10 85817005 | Flow cytometry, DNA analysis | 3.0 3.0 - Added by PITUS-16 project labelling index Donath-Landsteiner Ab Donath-Landsteiner antibody 21 Serum 61805007 | Haemolysin detection, cold, biphasic | 3.0 3.0 - Added by PITUS-16 project

Dopamine urine Urine Dopamine 14 Urine 30581005 | Dopamine measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Dopamine urine 24h Dopamine 24 hour urine; 24 hr urine 18 24 hr urine 313676001 | 24 hour urine dopamine output 3.0 3.0 - Changed preferred term from 'Dopamine 24 hr urine' Dopamine measurement | 2.0 - Added by PITUS-14 Working group 2 Dothiepin level 15 Serum 391534002 | Serum dosulepin level | 3.0 3.0 - Added by PITUS-16 project Drugs of abuse screen Drug Screen; Urine drug screen 21 314077000 | drugs of abuse urine screening test | 3.0 3.0 - Added synonyms 1.0 - Added by PUTS project Ear swab culture Ear swab; Ear culture 16 767021000168101 | Ear culture | 3.0 3.0 - Added by PITUS-16 project Ebola virus Ab Ebola virus antibodies 14 Blood fluids 121995001 | Measurement of Ebolavirus antibody | 3.0 3.0 - Added by PITUS-16 project

Ebola virus nucleic acid Ebola virus PCR 24 Blood fluids 832541000168105 | Ebolavirus nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project eGFR Estimated glomerular filtration rate; 4 Serum 444336003 | Calculation of quantitative glomerular 2.0 2.0 - Added by PITUS-14 Working group 2 Estimated GFR filtration rate based on creatinine concentration in serum or plasma | Electrolytes Elects; Es 12 Serum 20109005 | Electrolytes measurement, serum | 1.0 1.0 - Added by PUTS project Electrolytes faeces 19 Faeces 439948009 | Measurement of electrolytes in stool | 3.0 3.0 - Added by PITUS-16 project

Page 5 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History Electrolytes Urea Creatinine UEC; UE; EUC; EU 28 Serum 444164000 | Urea, electrolytes and creatinine 1.0 1.0 - Added by PUTS project measurement | Electrolytes urine 18 Urine 14830009 | Electrolytes measurement, urine | 3.0 3.0 - Added by PITUS-16 project Electrolytes urine 24h 22 24 hr urine 401261001 | 24 hour urine electrolytes measurement 3.0 3.0 - Added by PITUS-16 project | Electron microscopy EM 19 73512001 | Electron microscopic study | 3.0 3.0 - Added by PITUS-16 project Endomysial Ab Anti-endomysial Ab 13 Serum 271044002 | Serum endomysium antibody 1.0 1.0 - Added by PUTS project measurement | Endomysial Ab IgA Endomysial antibodies IgA 17 Serum 391509002 | Endomysial antibody IgA level | 3.0 3.0 - Added by PITUS-16 project Entamoeba Ab Entamoeba serology 12 Serum 122000001 | Measurement of Entamoeba histolytica 2.0 2.0 - Added by PITUS-14 Working group 2 antibody | Enterovirus Ab Enterovirus antibodies 14 Serum 104316000 | Measurement of enterovirus antibody | 3.0 3.0 - Added by PITUS-16 project

Enterovirus nucleic acid 24 122329007 |Enterovirus RNA assay | 3.0 3.0 - Added by PITUS-16 project Epstein-Barr nucleic acid 25 122330002 | Epstein Barr virus DNA assay | 3.0 3.0 - Added by PITUS-16 project Epstein-Barr virus serology EBV serology; Epstein-Barr virus Ab; 27 Serum 408219003 | Epstein-Barr virus serology | 1.0 3.0 - Added Synonum EBV Ab Infectious mononucleosis serology; EBV Ab 1.0 - Added by PUTS project

Epstein-Barr virus VCA IgG EBV VCA IgG 26 Serum 313586007 | Epstein-Barr virus capsid IgG 2.0 2.0 - Added by PITUS-14 Working group 2 measurement | Epstein-Barr virus VCA IgM EBV VCA IgM 26 Serum 391365005 | Epstein Barr virus viral capsid antigen IgM 2.0 2.0 - Added by PITUS-14 Working group 2 level | Erythrocyte sedimentation rate ESR 30 Whole blood 416838001 | Erythrocyte sedimentation rate 1.0 1.0 - Added by PUTS project measurement | Erythropoietin EPO 14 43979001 | Erythropoietin measurement | 3.0 3.0 - Added by PITUS-16 project Ethanol breath 14 Breath 1820004 | Ethanol measurement, breath | 3.0 3.0 - Added by PITUS-16 project Ethanol level Alcohol; EtOH 13 167009006 | Blood alcohol level | 1.0 1.0 - Added by PUTS project Ethanol level urine Alcohol urine 19 Urine 32845008 | Alcohol measurement, urine | 3.0 3.0 - Added by PITUS-16 project Ethosuximide 12 7962001 | Ethosuximide measurement | 3.0 3.0 - Added by PITUS-16 project Ethylene glycol 15 Serum 413669005 | Blood ethylene glycol level | 3.0 3.0 - Added by PITUS-16 project Extractable nuclear antigen Ab ENA Ab 30 Serum 46215003 | Antibody to extractable nuclear antigen 1.0 1.0 - Added by PUTS project measurement | Eye culture Eye swab 11 767571000168108 | Eye culture | 3.0 3.0 - Added by PITUS-16 project Factor II 9 Platelet poor 49151003 | Clotting factor II assay | 2.0 2.0 - Added by PITUS-14 Working group 2 plasma Factor II (prothrombin) G20210A mutation Prothrombin gene G20210A mutation 40 Platelet poor 444225007 | Factor II (prothrombin) G20210A 2.0 2.0 - Added by PITUS-14 Working group 2 plasma mutation detection | Factor II inhibitor 19 Plasma 29861003 | Circulating inhibitor assay, factor II | 3.0 3.0 - Added by PITUS-16 project Factor IX 9 Platelet poor 78882004 | Clotting factor IX assay | 2.0 2.0 - Added by PITUS-14 Working group 2 plasma Factor IX inhibitor 19 Plasma 24643008 | Circulating inhibitor assay, factor IX | 3.0 3.0 - Added by PITUS-16 project Factor V 8 Platelet poor 32514002 | Clotting factor V assay | 2.0 2.0 - Added by PITUS-14 Working group 2 plasma Factor V inhibitor 18 Plasma 103804006 | Factor V inhibitor assay | 3.0 3.0 - Added by PITUS-16 project Factor V Leiden Factor V Mutation 15 Platelet poor 165606004 | Factor V Leiden genotype | 2.0 2.0 - Added by PITUS-14 Working group 2 plasma Factor VII 11 Platelet poor 8196005 | Clotting factor VII assay | 2.0 2.0 - Added by PITUS-14 Working group 2 plasma Factor VII inhibitor 20 Plasma 103805007 | Factor VII inhibitor assay | 3.0 3.0 - Added by PITUS-16 project Factor VIII 11 Platelet poor 269819008 | Factor VIII assay | 2.0 2.0 - Added by PITUS-14 Working group 2 plasma Factor VIII Inhibitor FVIII Inhibitor 21 Platelet poor 71517003 | Circulating inhibitor assay, factor VIII | 2.0 2.0 - Added by PITUS-14 Working group 2 plasma Factor X 8 Platelet poor 9915003 | Clotting factor X assay | 2.0 2.0 - Added by PITUS-14 Working group 2 plasma Factor X inhibitor 18 Plasma 103806008 | Factor X inhibitor assay | 3.0 3.0 - Added by PITUS-16 project Factor XI 9 Platelet poor 88040009 | Clotting factor XI assay | 2.0 2.0 - Added by PITUS-14 Working group 2 plasma Factor XI inhibitor 19 Plasma 103807004 | Factor XI inhibitor assay | 3.0 3.0 - Added by PITUS-16 project Factor XII 10 Platelet poor 68902004 | Clotting factor XII assay | 2.0 2.0 - Added by PITUS-14 Working group 2 plasma Factor XII inhibitor 20 Plasma 103808009 | Factor XII inhibitor assay | 3.0 3.0 - Added by PITUS-16 project Factor XIII 11 Plasma 67738001 | Clotting factor XIII assay | 3.0 3.0 - Added by PITUS-16 project Factor XIII inhibitor 21 Plasma 36056007 | Factor XIII inhibitor assay | 3.0 3.0 - Added by PITUS-16 project Faecal dry weight 17 Faeces 103761008 | Specimen dry weight measurement | 3.0 3.0 - Added by PITUS-16 project

Faecal fat 3 days Faecal fat 72h; Faecal fat 72 hr 17 Faeces 853003 | Faecal fat measurement, 72-hour collection | 3.0 3.0 - Added by PITUS-16 project

Faeces culture Stool culture 14 Faeces 117028002 | Stool culture | 3.0 3.0 - Added by PITUS-16 project Faeces microscopy Stool microscopy 17 Faeces 252393000 | Stool microscopy | 3.0 3.0 - Added by PITUS-16 project Farmers lung precipitin Farmers lung precipitin IgG specific; 23 315121007 | Farmers lung antibody level | 3.0 3.0 - Added by PITUS-16 project Thermophilic actinomycetes precipitin Fasciola hepatica Ab Fasciola hepatica antibodies, Fascioliasis, 20 121901002 | Measurement of Fasciola hepatica 3.0 3.0 - Added by PITUS-16 project Fasciola antibodies antibody | Ferritin FER; Fe stores; Iron stores 8 Serum 269821003 | Serum ferritin measurement | 1.0 1.0 - Added by PUTS project Fibrinogen 10 Plasma 250346004 | Fibrinogen measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Filaria Microfilaria 7 Whole blood 171146004 | Filariasis screening | 3.0 3.0 - Added by PITUS-16 project Filaria Ab Filaria antibodies, Microfilaria, Loa Loa 10 Serum 121903004 | Measurement of filarial antibody | 3.0 3.0 - Added by PITUS-16 project serology, Wucheria serology Fine needle aspiration biopsy FNAB 29 48635004 | Fine needle aspiration biopsy | 3.0 3.0 - Added by PITUS-16 project Flecainide level Flecainide 16 Serum 391331009 | Serum flecainide level | 3.0 3.0 - Added synonym 'Flecainide' 1.0 - Added by PUTS project Flow cytometry Flow cytometry markers; Cell 14 Whole Blood; 50183007 | Flow cytometry, cell marker analysis | 3.0 3.0 - Added by PITUS-16 project immunophenotyping Fluid; Bone marrow; Tissue; Lymph node Fluorescence in situ hybridisation FISH 34 426329006 | Fluorescence in situ hybridisation | 3.0 3.0 - Added by PITUS-16 project Fluorescent Treponema Ab FTA 24 Serum 32746004 | Direct fluorescent antibody test for syphilis 1.0 1.0 - Added by PUTS project | Fluoxetine 10 Serum 425470001 | Fluoxetine measurement | 3.0 3.0 - Added by PITUS-16 project Folate red cell Folate RBC; Red cell folate; RCF 15 Whole blood 69152001 | Folic acid measurement, RBC | 3.0 3.0 - Added synonym 'RCF' 1.0 - Added by PUTS project Folate serum Folic acid; FOL; Folate 12 Serum 60306005 | Folic acid measurement, serum | 3.0 3.0 - Added synonym 'Folate' 1.0 - Added by PUTS project Follicle stimulating hormone FSH 29 Serum 273971007 | Serum follicle stimulating hormone 1.0 1.0 - Added by PUTS project measurement | Francisella tularensis Ab Francisella tularensis antibodies; Tularemia 25 Serum 104284005 | Measurement of Francisella tularensis 3.0 3.0 - Added by PITUS-16 project antibody | Francisella tularensis culture Tularemia 30 832561000168109 | Francisella tularensis culture | 3.0 3.0 - Added by PITUS-16 project Francisella tularensis nucleic acid Francisella tularensis PCR; Tularemia 35 832551000168107 | Francisella tularensis nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | Free androgen index FAI 20 Serum; Plasma 271223005 | Free androgen index measurement | 1.0 1.0 - Added by PUTS project Free cortisol urine 19 24hr urine 22820002 | Cortisol measurement, free, urine | 3.0 3.0 - Added by PITUS-16 project Free deoxypyridinoline urine Urine Free Deoxypyridinoline; Urine DPD 28 Urine 408251002 | Urine deoxypyridinoline level | 2.1 2.1 - Changed preferred term from 'Free Deoxypyridinoline urine' 2.0 - Added by PITUS-14 Working group 2

Free light chains Light chains; FLC; SFLC 17 Serum 417486008 | Light chain level | 3.0 3.0 - Added by PITUS-16 project Free prostate specific Ag Free PSA 25 395146000 | Free:total prostate specific antigen ratio | 1.0 1.0 - Added by PUTS project

Free T3 T3; Free triiodothyronine; Triiodothyronine 7 Serum 313836009 | Serum free triiodothyronine 1.0 1.0 - Added by PUTS project measurement | Free T4 T4; Free thyroxine; Thyroxine 7 Serum 313837000 | Serum free T4 measurement | 1.0 1.0 - Added by PUTS project Free testosterone Testosterone free ; Testosterone unbound 17 20436004 | Testosterone measurement, unbound | 1.0 1.0 - Added by PUTS project

Frozen section 14 27204007 | Tissue frozen section technique, complete 3.0 3.0 - Added by PITUS-16 project | Fructosamine 12 Serum 7740009 | Fructosamine measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Full blood count FBC; Full blood picture; Complete blood 16 Whole blood 26604007 | Complete blood count | 3.0 3.0 - Added synonym 'Antenatal screen' count; CBC; Full blood examination; FBE; 1.0 - Added by PUTS project CBE; Antenatal screen Fungal nucleic acid Fungal antigen 19 118148009 | Fungal nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project G-6-PD quantitative Glucose-6-phosphate dehydrogenase 19 Whole blood 104700000 | Glucose-6-phosphate dehydrogenase 2.0 2.0 - Added by PITUS-14 Working group 2 quantitative; G6PD measurement, quantitative | G-6-PD screen Glucose-6-phosphate dehyrogenase screen; 13 Whole blood 104701001 | Glucose-6-phosphate dehydrogenase 3.0 3.0 - Added synonym ' G6PD screen' G6PD; G6PD screen measurement, screen | 2.0 - Added by PITUS-14 Working group 2 GAD65 Ab Neuronal antibodies; GAD65 antibodies; 8 Serum 117907009 | Measurement of glutamate 3.0 3.0 - Added by PITUS-16 project Glutamate decarboxylase 65 antibodies decarboxylase 65 antibody | Galactose 9 Serum 6159009 | Galactose measurement | 3.0 3.0 - Added by PITUS-16 project Galactosidase beta 18 16308000 | Beta-galactosidase measurement | 3.0 3.0 - Added by PITUS-16 project Gamma glutamyltransferase GGT; Gamma GT; Gamma glutamyl 25 Serum 313849004 | Serum gamma-glutamyl transferase 1.0 1.0 - Added by PUTS project transpeptidase; GGTP measurement | Ganglioside Ab Ganglioside GM1 IgG; Ganglioside GM1 IgM; 14 Serum 117263002 | Measurement of ganglioside antibody | 3.0 3.0 - Added by PITUS-16 project Ganglioside GQ1b Ab Gastrin 7 Serum 444264005 | Quantitative measurement of gastrin in 2.0 2.0 - Added by PITUS-14 Working group 2 fasting serum or plasma specimen | GBM Ab Glomerular basement membrane antibodies; 6 Serum 313539008 | GBM antibody measurement | 3.0 3.0 - Added by PITUS-16 project GBM antibodies; alpha 3 subunit Type IV collagen antibody

Page 6 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History Gentamicin level peak Gentamicin post-dose 21 Serum 442200002 | Measurement of gentamicin peak 1.0 1.0 - Added by PUTS project concentration | Gentamicin level random Genta 23 Serum 439210007 | Measurement of gentamicin in random 1.0 1.0 - Added by PUTS project specimen | Gentamicin level trough Gentamicin pre-dose 23 Serum 442199000 | Measurement of gentamicin trough 1.0 1.0 - Added by PUTS project concentration | Gentamycin level 16 Serum 313714001 | Serum gentamicin measurement | 1.0 1.0 - Added by PUTS project Gestational diabetes screen Glucose Challenge Test; 1 hour Glucose 27 313194008 | Glucose load test | 1.0 1.0 - Added by PUTS project Challenge Test; Glucose load test Giardia lamblia Ag Giardia lamblia EIA 18 121906007 | Giardia lamblia antigen assay | 3.0 3.0 - Added by PITUS-16 project Giardia lamblia nucleic acid Giardia nucleic acid; Giardia PCR 28 832831000168103 | Giardia lamblia nucleic acid assay 3.0 3.0 - Added by PITUS-16 project | Gliadin Ab 10 Serum 104376009 | Gliadin antibody measurement | 1.0 1.0 - Added by PUTS project Globulins 9 Serum 104979009 | Total globulins measurement | 3.0 3.0 - Added by PITUS-16 project Glucagon 8 70451005 | Glucagon measurement | 3.0 3.0 - Added by PITUS-16 project Glucose CSF CSF Glucose; Cerebrospinal fluid Glucose 11 CSF 69125006 | Glucose measurement, CSF | 2.0 2.0 - Added by PITUS-14 Working group 2

Glucose fasting FBG; FBS; BSL; Fasting blood glucose 15 Serum; Plasma 271062006 | Fasting blood glucose measurement | 1.0 1.0 - Added by PUTS project

Glucose random BSL; RBS; Sugar; Random blood glucose; RBG 14 Serum; Plasma 271061004 | Random blood glucose measurement | 1.0 1.0 - Added by PUTS project

Glucose test strip 18 104686004 | Glucose measurement, blood, test strip | 3.0 3.0 - Added by PITUS-16 project

Glucose tolerance test GTT; OGTT 22 Whole blood 113076002 | Glucose tolerance test | 1.0 1.0 - Added by PUTS project Glucose tolerance test antenatal 32 699731004 | Glucose tolerance test, antenatal | 3.0 3.0 - Added by PITUS-16 project Glucose urine Urine Glucose 13 Urine 30994003 | Glucose measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Glucose urine 24h Glucose 24 hour urine; 24 hour urine Glucose 17 24 hr urine 444122000 | Quantitative measurement of glucose in 3.0 3.0 - Changed preferred term from 'Glucose 24 hr urine' 24 hour urine specimen | 2.0 - Added by PITUS-14 Working group 2 Glutamic acid decarboxylase Ab GAD Ab; Diabetes related antibodies; 30 Serum 391548002 | Glutamic acid decarboxylase antibody 3.0 3. 0 - Added synonyms 'Diabetes related antibodies; Diabetes- Diabetes-related autoantibodies; Neuronal level | related autoantibodies; Neuronal antibodies; Stiff person syndrome' antibodies; Stiff person syndrome

Glutamine 9 104698009 | Glutamine measurement | 3.0 3.0 - Added by PITUS-16 project Glycine CSF 11 CSF 442552000 | Measurement of glycine in cerebrospinal 3.0 3.0 - Added by PITUS-16 project fluid specimen | Gram stain 10 Body fluids; 391245000 | Gram stain microscopy | 2.0 2.0 - Added by PITUS-14 Working group 2 Wound swabs; Sputum Growth hormone GH 14 Serum 80874005 | Growth hormone measurement | 2.1 2.1 - Changed preferred term from ‘Growth Hormone’ 2.0 - Added by PITUS-14 Working group 2 Haematocrit Haematocrit only; HCT; Packed cell volume; 11 Whole blood 28317006 | Haematocrit determination | 1.0 1.0 - Added by PUTS project PCV Haemochromatosis genotyping Genetic haemochromatosis screen; HFE 27 401085002 | Haemochromatosis gene screening test | 1.0 1.0 - Added by PUTS project

Haemoglobin Hb; Haemoglobin only 12 Whole blood 271026005 | Haemoglobin level estimation | 1.0 1.0 - Added by PUTS project Haemoglobin electrophoresis Haemoglobin EPP; Haemoglobin EPG; Hb 28 Whole blood 104145007 | Haemoglobin electrophoresis | 3.0 3.0 - Added synonym 'Hb electrophoresis' EPP; Hb EPG; Haemoglobinopathy screen; Hb 1.0 - Added by PUTS project electrophoresis Haemoglobin F 13 Whole blood 23244001 | Haemoglobin F level | 3.0 3.0 - Added by PITUS-16 project Haemoglobin S level HbS; Sickle cell 19 Whole blood 271510004 | Haemoglobin S measurement | 3.0 3.0 - Added by PITUS-16 project Haemoglobin urine 17 Urine 275714003 | Urine dipstick for haemoglobin | 3.0 3.0 - Added by PITUS-16 project Haemophilus influenzae nucleic acid 35 122332005 | Haemophilus influenzae rRNA assay | 3.0 3.0 - Added by PITUS-16 project

Haemosiderin urine 18 Urine 252301006 | Urinary haemosiderin detection | 3.0 3.0 - Added by PITUS-16 project Hantavirus Ab Hantavirus antibodies 13 121908008 | Measurement of Hantavirus antibody | 3.0 3.0 - Added by PITUS-16 project

Hantavirus nucleic acid Hantavirus PCR 23 398408001 | Hantavirus nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project Haptoglobin 11 Serum 166580005 | Serum haptoglobin measurement | 1.0 1.0 - Added by PUTS project HbA1c Haemoglobin A1c; Glycated Hb; GHB; 6 Blood 43396009 | Haemoglobin A1c measurement | 1.0 1.0 - Added by PUTS project Glycosylated haemoglobin HDL cholesterol HDL; HDLC; HDL-C; High density lipoprotein 15 Serum 166832000 | Serum HDL cholesterol measurement | 1.0 1.0 - Added by PUTS project cholesterol Heinz body Heinz body screen 10 Whole blood 74216007 | Heinz body determination | 3.0 3.0 - Added by PITUS-16 project Helicobacter pylori Ag faeces Bacterial antigen; Faeces H pylori antigen; 29 Faeces 118034007 | Helicobacter pylori antigen assay | 3.0 3.0 - Added synonyms Faeces H pylori Ag 1.0 - Added by PUTS project Helicobacter pylori breath test Helicobacter breath test; Urea breath test; 31 Breath 164791003 | Helicobacter pylori breath test | 3.0 3.0 - Changed preferred term from 'Urea breath test'; Added C14 Urea breath test synonyms 1.0 - Added by PUTS project Helicobacter pylori culture H pylori culture 27 122214008 | Helicobacter pylori culture | 3.0 3.0 - Added by PITUS-16 project Helicobacter pylori IgG H.pylori IgG Ab 23 Serum; Blood 313942007 | Helicobacter pylori IgG antibody 3.0 3.0 - Changed preferred term from 'Helicobacter pylori IgG Ab' measurement | 1.0 - Added by PUTS project

Hendra virus Ab Equine morbillivirus antibodies; Hendra 15 443278004 | Measurement of Hendra virus antibody | 3.0 3.0 - Added by PITUS-16 project antibodies Hendra virus nucleic acid Hendra virus PCR 25 444181009 | Hendra virus nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project Heparin monitoring low molecular weight Low molecular weight Heparin monitoring 39 103839006 | Low molecular weight heparin assay | 2.1 2.1 - ‘Heparin monitoring low molecular weight’ was ‘Heparin monitoring Low molecular weight’ 2.0 - Added by PITUS-14 Working group 2 Heparin monitoring unfractionated Unfractionated Heparin monitoring; Heparin 33 Plasma 103838003 | Unfractionated heparin assay | 2.0 2.0 - Added by PITUS-14 Working group 2 assay Heparin-induced thrombocytopenia screen HITTS screen 39 Plasma 408230000 | Heparin induced thrombocytopenia 3.0 3.0 - Added by PITUS-16 project screening test | Hepatitis A IgG Hep A IgG Ab; Hepatitis A immune status 15 Serum 13070009 | Hepatitis A virus antibody, IgG type | 3.0 3.0 - Changed preferred term from 'Hepatitis A IgG Ab' 1.0 - Added by PUTS project Hepatitis A IgM Hep A IgM Ab 15 Serum 88159009 | Hepatitis A virus antibody, IgM type | 3.0 3.0 - Changed preferred term from 'Hepatitis A IgM Ab' 1.0 - Added by PUTS project Hepatitis A total Ab Hep A Total A; Hepatitis A immune status 20 Serum 104374007 | Hepatitis A virus antibody, total 1.0 1.0 - Added by PUTS project measurement | Hepatitis B core IgM Hep B core IgM Ab 20 Serum 315132007 | Hepatitis B core IgM level | 3.0 3.0 - Changed preferred term from 'Hepatitis B core IgM Ab' 1.0 - Added by PUTS project Hepatitis B core total Ab Hep B core total Ab 25 Serum 59582004 | Hepatitis B core antibody measurement | 1.0 1.0 - Added by PUTS project

Hepatitis B e Ab HBeAb 16 Serum 79172007 | Hepatitis Be antibody measurement | 3.0 3.0 - Changed LOINC code from 315134008 as this is now inacive 1.0 - Added by PUTS project

Hepatitis B e Ag HBeAg 16 Serum 313476009 | Hepatitis B e antigen test | 1.0 1.0 - Added by PUTS project Hepatitis B nucleic acid Hepatitis B DNA; Hepatitis B PCR 25 Serum 398468003 | Hepatitis B nucleic acid assay | 1.0 1.0 - Added by PUTS project Hepatitis B serology Hep B Ab; Antenatal screen 20 Serum 171122006 | Hepatitis B screening | 3.0 3.0 - Added synonyms 'Hep B Ab; Antenatal screen' 1.0 - Added by PUTS project Hepatitis B surface Ab HBsAb; Hepatitis B immunity; Hepatitis B 22 Serum 315130004 | Hepatitis B surface antibody level | 1.0 1.0 - Added by PUTS project Immune status; Hepatitis B post vaccination

Hepatitis B surface Ag HBsAg 22 Serum 47758006 | Hepatitis B surface antigen measurement | 3.0 3.0 -Changed LOINC code from 315131000 as it is now inactive 1.0 - Added by PUTS project Hepatitis C genotyping Hepatitis C Genotype 22 Serum 397662006 | Hepatitis C virus genotype determination 1.0 1.0 - Added by PUTS project | Hepatitis C nucleic acid Hep C NAD; Hep C PCR; Hep C RNA 25 Serum 398513000 | Hepatitis C nucleic acid assay | 1.0 1.0 - Added by PUTS project Hepatitis C serology Hep C Ab; Antenatal screen 20 Serum 64411004 | Hepatitis C antibody measurement | 3.0 3.0 - Changed LOINC code from 313612007 as it is now inactive. Added synonym 'Antenatal screen' 1.0 - Added by PUTS project Hepatitis C viral load Hep C viral load 22 Serum 395197008 | Hepatitis C viral load | 3.0 3.0 - Added synonym 'Hep C viral load' 1.0 - Added by PUTS project Hepatitis D Ab Hep D Ab; Hepatitis Delta Ab 14 Serum 61082006 | Hepatitis D antibody measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Hepatitis D Ag Hep D Ag; Hepatitis Delta Ag 14 Serum 47644001 | Hepatitis D antigen measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Hepatitis E Ab HEV Ab 14 Serum 17092007 | Hepatitis E antibody measurement | 3.0 3.0 - Added by PITUS-16 project Hepatitis E IgG Hep E IgG 15 Serum 401243005 | Hepatitis E IgG level | 2.1 2.1 - Changed preferred term from 'Hepatitis E IgG' 2.0 - Added by PITUS-14 Working group 2 Hepatitis E IgM Hep E IgM 15 Serum 401242000 | Hepatitis E IgM level | 2.1 2.1 - Changed preferred term to 'Hepatitis E IgM Ab' (was 'Hepatitis E IgM') 2.0 - Added by PITUS-14 Working group 2 Hepatitis E nucleic acid 24 767561000168102 | Hepatitis E nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project Hepatitis G Ab 14 Serum 397581006 | Hepatitis G antibody measurement | 3.0 3.0 - Added by PITUS-16 project Hepatitis serology 18 Serum 52570007 | Hepatitis panel measurement | 1.0 1.0 - Added by PUTS project Herpes simplex Ab HSV Ab 17 Serum 315138006 | Herpes simplex antibody level | 1.0 1.0 - Added by PUTS project Herpes simplex virus nucleic acid Herpes PCR; HSV PCR 34 Serum 398443000 | Herpes simplex nucleic acid assay | 3.0 3.0 - Added synonym 'HSV PCR' 1.0 - Added by PUTS project Histology Histo; Histopathology; Tissue pathology 9 252416005 | Histopathology test | 1.0 1.0 - Added by PUTS project Histone Ab Histone antibodies 10 Serum 90952003 | Antibody to histone measurement | 3.0 3.0 - Added by PITUS-16 project HIV genotypic resistance Human immunodeficiency virus genotypic 24 Serum 446987006 | HIV 1 genotyping | 3.0 3.0 - Added by PITUS-16 project resistance testing HIV p24 antigen P 24 antigen HIV; P24 16 Serum 104332002 | HIV p24 antigen test | 2.0 2.0 - Added by PITUS-14 Working group 2 HIV serology HIV; HIV Ab; HIV Ag; HIV Ab/Ag; Human 12 Serum 171121004 | HIV screening | 3.0 3.0 - Added synonyms; Changed SNOMED code from 165813002 immunodeficiency virus test; HIV screen; HIV 1.0 - Added by PUTS project combo assay HIV viral load 14 Serum 315124004 | HIV viral load | 1.0 1.0 - Added by PUTS project HLA B27 7 417429003 | HLA-B27 typing | 1.0 1.0 - Added by PUTS project Homocysteine HCY 13 Serum 313741006 | Serum homocysteine measurement | 2.0 2.0 - Added by PITUS-14 Working group 2

Page 7 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History Homogentisic acid urine 23 Urine 4337003 | Homogentisic acid measurement | 3.0 3.0 - Added by PITUS-16 project Homovanillic acid urine 24h HVA; Urine Homovanillic acid 27 24 hr urine 391372006 | 24 hour urine homovanillylmandelic acid 3.0 3.0 - Changed preferred term from 'Homovanillic acid 24 hr urine' output | 2.0 - Added by PITUS-14 Working group 2

HTLV Ab HTLV; T-lymphotropic virus Ab; HTLV 7 Serum 117754000 | Measurement of Human T-lymphotropic 2.0 2.0 - Added by PITUS-14 Working group 2 serology virus 1 antibody and Human T-lymphotropic virus 2 antibody | Hu Ab Neuronal antibodies; Paraneoplastic 5 Serum; CSF 313599005 | Hu antibody measurement | 3.0 3.0 - Added by PITUS-16 project neurologic antibodies; Cerebellar IIF; ANNA; ANNA-1; Antineuronal nuclear antibodies

Human papillomavirus DNA HPV; HPV PCR 24 35904009 | Human papillomavirus DNA detection | 2.1 2.1 - Changed preferred term from ‘Human Papillomavirus DNA’ 2.0 - Added by PITUS-14 Working group 2

Human papillomavirus typing HPV typing 27 Tissue 67778008 | Human papillomavirus typing | 3.0 3.0 - Added by PITUS-16 project Huntington disease genetic test Huntington chorea 31 DNA 437742006 | Huntington disease gene mutation carrier 2.1 2.1 - Changed preferred term from ‘Huntington Disease genetic test’ detection test | 2.0 - Added by PITUS-14 Working group 2

Hydatid Ab Echinococcus granulosa serology; Hydatid 10 Serum 315141002 | Hydatid antibody level | 2.0 2.0 - Added by PITUS-14 Working group 2 serology Hydroxybutyrate Beta hydroxybutyrate, Ketones - plasma, 15 104546003 | Beta-hydroxybutyrate measurement | 3.0 3.0 - Added by PITUS-16 project Ketones Hydroxychloroquine 18 105208003 | Hydroxychloroquine measurement | 3.0 3.0 - Added by PITUS-16 project Hydroxymethylglutaryl-CoA lyase HMG CoA lyase 31 104743008 | Hydroxymethylglutaryl-CoA lyase 3.0 3.0 - Added by PITUS-16 project measurement | Hydroxyproline urine 20 Urine 271011008 | Urine hydroxyproline measurement | 3.0 3.0 - Added by PITUS-16 project

IGF-1 IGF1; Insulin Growth Factor 1; Somatomedin 5 Serum 313787000 | Serum insulin-like growth factor 1 2.0 2.0 - Added by PITUS-14 Working group 2 C measurement | IGF-BP3 IGFBP3 7 Serum 414519004 | Insulin-like growth factor binding protein 2.0 2.0 - Added by PITUS-14 Working group 2 3 level | IM test IM; Paul Bunnell; Monospot; Infectious 7 Serum; Plasma 269831005 | Infectious mononucleosis test | 1.0 1.0 - Added by PUTS project mononucleosis qualitative screen Immunoelectrophoresis IEP; IEPG; Immunotyping; 21 25884002 | Immunoelectrophoresis | 3.0 3.0 - Added by PITUS-16 project Immunosubtraction; Immunofixation; IFE

Immunofluorescence direct tissue Direct tissue immunofluorescence 32 127796002 | Direct tissue immunofluorescence 3.0 3.0 - Added by PITUS-16 project procedure | Immunoglobulin Iggs; Gammaglobulins 14 Serum 42441008 | Immunoglobulin measurement | 3.0 3.0 - Changed preferred term from 'Immunoglobulins' 1.0 - Added by PUTS project Immunoglobulin A IgA 16 Serum 31651002 | Immunoglobulin A measurement | 3.0 3.0 - Changed preferred term from 'Immunoglobulins A' 2.0 - Added by PITUS-14 Working group 2 Immunoglobulin A CSF Cerebrospinal fluid Immunoglobulins A; CSF 20 CSF 443687003 | Quantitative measurement of IgA in 3.0 3.0 - Added by PITUS-16 project Immunoglobulins A; IgA CSF cerebrospinal fluid specimen | Immunoglobulin D 16 68388009 | Immunoglobulin D measurement | 3.0 3.0 - Added by PITUS-16 project Immunoglobulin E total IgE 22 Serum 41960005 | Immunoglobulin E measurement | 1.0 1.0 - Added by PUTS project Immunoglobulin G IgG 16 Serum 45293001 | Immunoglobulin G measurement | 3.0 3.0 - Changed preferred term from 'Immunoglobulins G' 2.0 - Added by PITUS-14 Working group 2 Immunoglobulin G CSF Cerebrospinal fluid Immunoglobulins G; CSF 20 CSF 313683008 | Cerebrospinal fluid IgG measurement | 3.0 3.0 - Changed preferred term from 'Immunoglobulins G CSF' Immunoglobulins G; IgG CSF 2.0 - Added by PITUS-14 Working group 2 Immunoglobulin G subclass IgG subclass 25 Serum 27083005 | Immunoglobulin G subclass measurement 2.0 2.0 - Added by PITUS-14 Working group 2 | Immunoglobulin G1 IgG1 17 Serum 79627000 | Immunoglobulin G subclass, G1 2.0 2.0 - Added by PITUS-14 Working group 2 measurement | Immunoglobulin G2 IgG2 17 Serum 56091006 | Immunoglobulin G subclass, G2 2.0 2.0 - Added by PITUS-14 Working group 2 measurement | Immunoglobulin G3 IgG3 17 Serum 63414002 | Immunoglobulin G subclass, G3 2.0 2.0 - Added by PITUS-14 Working group 2 measurement | Immunoglobulin G4 IgG4 17 Serum 16948004 | Immunoglobulin G subclass, G4 2.0 2.0 - Added by PITUS-14 Working group 2 measurement | Immunoglobulin heavy chain gene 31 Serum 35389006 | Immunoglobulin gene rearrangement 2.0 2.0 - Added by PITUS-14 Working group 2 assay | Immunoglobulin M IgM 16 Serum 45764000 | Immunoglobulin M measurement | 3.0 3.0 - Changed preferred term from 'Immunoglobulins M' 2.0 - Added by PITUS-14 Working group 2 Immunoglobulin M CSF Cerebrospinal fluid Immunoglobulins M; CSF 20 CSF 443992004 | Quantitative measurement of IgM in 3.0 3.0 - Added by PITUS-16 project Immunoglobulins M; IgM CSF cerebrospinal fluid specimen | Immunohistochemistry 20 Serum 117617002 | Immunohistochemistry procedure | 3.0 3.0 - Added by PITUS-16 project Indirect Coombs test Indirect antiglobulin test; IAT; IAGT 20 16742006 | Indirect Coombs test | 3.0 3.0 - Added by PITUS-16 project Infectious diarrhea nucleic acid Faecal PCR; Campylobacter; Salmonella; 32 843431000168107 | Faecal enteropathogen nucleic 3.0 3.0 - Added by PITUS-16 project Norovirus; Rotavirus; Shigella; Saprovirus acid assay | Infectious respiratory nucleic acid Respiratory PCR; Rhinovirus nucleic acid 35 843441000168103 | Respiratory pathogen nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | Influenza Ab Influenza serology 12 Serum 104310006 | Influenzavirus antibody assay | 1.0 1.0 - Added by PUTS project Influenza virus A Ag Influenza virus A antigen 20 122349003 | Influenza virus A antigen assay | 3.0 3.0 - Added by PITUS-16 project Influenza virus A and B Ag Influenza virus antigen; Influenza POCT; 26 118089005 | Influenza virus A AND B antigen assay | 3.0 3.0 - Added by PITUS-16 project Influenza Point of Care test; Flu Influenza virus B Ag Influenza virus B antigen 20 Nasal swab; Nasal 122350003 | Influenza virus B antigen assay | 3.0 3.0 - Added by PITUS-16 project wash or aspirate; Throat swab

INR International normalised ratio 3 Plasma 440685005 | Calculation of international normalised 1.0 1.0 - Added by PUTS project ratio | Insulin 7 Serum 16890009 | Insulin measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Insulin Ab Diabetes related antibodies; Diabetes-related 10 serum 37076009 | Insulin antibody measurement | 3.0 3.0 - Added by PITUS-16 project autoantibodies; Insulin antibodies

Insulin free 12 104753009 | Insulin, free measurement | 3.0 3.0 - Added by PITUS-16 project Intercellular cement substance Ab ICCS; Pemphigus antibodies; Pemphigus Ab 33 Serum 412898001 | Pemphigus antibody measurement | 3.0 3.0 - Added by PITUS-16 project

Intercellular substance Ab ICCS 26 serum 117910002 | Measurement of intercellular structure 3.0 3.0 - Added by PITUS-16 project antibody | Interleukin 6 IL-6 13 22766004 | IL-6 assay | 3.0 3.0 - Added by PITUS-16 project Intrinsic factor Ab Intrinsic factor antibodies; IFA; IF Ab 19 Serum 74261006 | Intrinsic factor antibody measurement | 3.0 3.0 - Added synonyms 'Intrinsic factor antibodies; IF Ab' 2.1 - Changed preferred term from ‘Intrinsic factor antibodies’ 2.0 - Added by PITUS-14 Working group 2

Iodine urine 12 Spot urine; 24 hr 113078001 | Iodine, urine free measurement | 3.0 3.0 - Added by PITUS-16 project urine Iron Fe level; IRN; Fe 4 Serum 250216004 | Serum iron measurement | 1.0 1.0 - Added by PUTS project Iron studies Fe studies 12 Serum 269820002 | Serum iron tests | 1.0 1.0 - Added by PUTS project Iron urine 24h Urine Iron 14 24 hr urine 313532004 | 24 hour urine iron output measurement | 3.0 3.0 - Changed preferred term from 'Iron 24 hr urine' 2.0 - Added by PITUS-14 Working group 2 Islet cell Ab Diabetes related antibodies; Diabetes-related 13 Serum 64135003 | Islet cell antibody measurement | 3.0 3.0 - Added by PITUS-16 project autoantibodies; Pancreatic antibodies; Pancreatic islet cell antibodies; ICA

Japanese encephalitis virus Ab Japanese encephalitis virus antibody; 30 Serum 122015000 | Measurement of Japanese encephalitis 3.0 3.0 - Added by PITUS-16 project Arbovirus antibody virus antibody | Japanese encephalitis virus nucleic acid Japanese encephalitis PCR; JE PCR; JE NAA 40 Serum; CSF 122372001 | Japanese encephalitis virus RNA assay | 3.0 3.0 - Added by PITUS-16 project

Jo-1 Ab Anti-synthetase antibodies; Histidyl-tRNA 7 Serum 33732007 | Antibody to JO-1 measurement | 3.0 3.0 - Added by PITUS-16 project synthetase antibodies; Jo-1 antibodies; ENA JO-1 Kleihauer Foetal Maternal Haemorrhage Estimation 9 Whole blood 714683008 | Haemoglobin F measurement using 3.0 3.0 - Changed LOINC code from 35793002 as it is inactive. Kleihauer-Betke method | 2.0 - Added by PITUS-14 Working group 2 Kunjin virus Ab Kunjin virus antibody; Arbovirus antibody 15 767691000168108 | Measurement of Kunjin virus 3.0 3.0 - Added by PITUS-16 project antibody | Kunjin virus nucleic acid Arbovirus nucleic acid 25 778361000168101 | Kunjin virus nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project

Lactase - small bowel mucosa Disaccharidases - small bowel mucosa 28 443420006 | Measurement of disaccharidase activity 3.0 3.0 - Added by PITUS-16 project of intestine | Lactate Lactic acid 7 Plasma 390996000 | Plasma lactate level | 1.0 1.0 - Added by PUTS project Lactate blood gas Blood Gas Lactate 17 394960005 | Arterial blood lactate level | 2.0 2.0 - Added by PITUS-14 Working group 2 Lactate CSF Cerebrospinal fluid Lactate; CSF Lactate; CSF 11 CSF 313526009 | Cerebrospinal fluid lactate measurement 2.0 2.0 - Added by PITUS-14 Working group 2 Lactic acid | Lactate dehydrogenase LD; LDH 21 Serum 313854008 | Serum lactate dehydrogenase 1.0 1.0 - Added by PUTS project measurement | Lactate dehydrogenase isoenzymes LD isoenzymes 32 88932000 | Lactate dehydrogenase isoenzymes 3.0 3.0 - Added by PITUS-16 project measurement | Lactose intolerance - breath test Hydrogen breath test 33 Breath 443661003 | Hydrogen breath test using lactose | 3.0 3.0 - Added by PITUS-16 project Lactose tolerance test 22 34271001 | Lactose tolerance test | 3.0 3.0 - Added by PITUS-16 project Lassa virus Ab Lassa virus antibodies; Arenavirus 14 122351004 | Measurement of Lassa virus antibody | 3.0 3.0 - Added by PITUS-16 project

Lassa virus nucleic acid Lassa virus PCR; Arenavirus 24 833941000168105 | Lassa virus nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project Laxatives 9 Random urine and 120640001 | Laxative identification | 3.0 3.0 - Added by PITUS-16 project faeces

Page 8 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History LDL cholesterol LDL; LDLC; LDL-C; Low density lipoprotein 15 Serum 166833005 | Serum LDL cholesterol measurement | 1.0 1.0 - Added by PUTS project cholesterol Lead Pb 5 Whole blood 8655006 | Lead measurement, quantitative, blood | 1.0 1.0 - Added by PUTS project

Lead urine Urine Lead; Urine Pb 10 Urine 63666004 | Lead measurement, quantitative, urine | 2.0 2.0 - Added by PITUS-14 Working group 2

Lead urine 24h 24 hr urine lead; 24 hr Urine Pb 14 24 hr urine 391482006 | 24 hour urine lead output | 3.0 3.0 - Changed preferred term from 'Lead 24 hr urine' 2.0 - Added by PITUS-14 Working group 2 Lecithin-sphingomyelin ratio L/S ratio; Foetal lung maturity 28 Amniotic fluid 68297005 | Amniotic fluid lecithin/sphingomyelin ratio 3.0 3.0 - Added by PITUS-16 project | Legionella Ab Legionella serology 13 Serum 104287003 | Measurement of Legionella species 1.0 1.0 - Added by PUTS project antibody | Legionella Ag Legionella sp antigen; Bacterial antigen 13 Bronchial 398489007 | Legionella antigen assay | 3.0 3.0 - Added by PITUS-16 project brushing; Bronchial washing; Lung biopsy; Sputum Legionella culture 18 Sputum 122216005 | Legionella species culture | 3.0 3.0 - Added by PITUS-16 project Legionella IgG 14 Serum 134247007 | Legionella IgG level | 2.0 2.0 - Added by PITUS-14 Working group 2 Legionella IgM 14 Serum 134248002 | Legionella IgM level | 2.0 2.0 - Added by PITUS-14 Working group 2 Legionella nucleic acid 23 wg3 767761000168109 | Legionella species nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | Legionella pneumophila serogroup 1 Ag Legionella pneumophila 1 antigen; Legionella 37 Urine 122353001 | Legionella pneumophila 1 antigen assay | 3.0 3.0 - Added by PITUS-16 project urinary Ag; Rapid Legionella urinary antigen; Bacterial antigen Leptin 6 Serum 117694008 | Leptin measurement | 3.0 3.0 - Added by PITUS-16 project Leptospiral Ab Leptospiral serology 14 Serum 134244000 | Leptospiral antibody level | 2.0 2.0 - Added by PITUS-14 Working group 2 Lipase 6 Serum 271232007 | Serum lipase measurement | 1.0 1.0 - Added by PUTS project Lipids Chols and Trigs 6 Serum 252150008 | Fasting lipid profile | 1.0 1.0 - Added by PUTS project Lipoprotein (a) Lp(a); Lipoprotein little a 15 Serum 121806006 | Lipoprotein (a) measurement | 3.0 3.0 - Added by PITUS-16 project Lipoprotein electrophoresis Lipoprotein EPG 27 Serum 4727005 | Lipoprotein electrophoresis | 3.0 3.0 - Added by PITUS-16 project Liquid based cervical cytology ThinPrep; Surepath 31 Cervix 417036008 | Liquid based cervical cytology screening | 1.0 1.0 - Added by PUTS project

Lithium Li 7 Serum 269871000 | Serum lithium measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Liver function tests LFT 20 Serum 271552009 | Liver function tests - general | 1.0 1.0 - Added by PUTS project Liver/Kidney Microsome Ab LKM Ab 25 Serum 122157009 | Measurement of liver and kidney 2.0 2.0 - Added by PITUS-14 Working group 2 microsomal antibody | Lupus anticoagulant LA; Lupus inhibitor; LAC 19 63300003 | Lupus anticoagulant assay | 1.0 1.0 - Added by PUTS project Luteinising hormone LH 20 Serum 273969007 | Serum LH measurement | 1.0 1.0 - Added by PUTS project Lyme disease nucleic acid 25 398352008 | Borrelia burgdorferi nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project

Lyme disease serology Lyme disease test 21 310565008 | Lyme ELISA test | 3.0 3.0 - Added by PITUS-16 project Lymphocyte subsets Lymphocyte surface markers; LSM; 18 Whole Blood 313392000 | Cluster of differentiation antigen count 3.0 3.0 - Added by PITUS-16 project Lymphocyte immunophenotyping; procedure | Lymphocyte markers; T & B cells subsets; T cells subsets; B cells subsets Lymphocytotoxic Ab Lymphocytotoxic antibodies 18 252361008 | Lymphocytotoxicity assay | 3.0 3.0 - Added by PITUS-16 project Macroprolactin level 20 Serum 407679003 | Serum macroprolactin level | 3.0 3.0 - Added by PITUS-16 project MAG Ab MAG antibody; Myelin associated 6 Serum 117911003 | Measurement of myelin associated 3.0 3.0 - Added by PITUS-16 project glycoprotein Ab glycoprotein antibody | Magnesium Mg 9 Serum 63571001 | Magnesium measurement, serum | 1.0 1.0 - Added by PUTS project Magnesium faeces 16 Faeces 832381000168107 | Faecal magnesium measurement 3.0 3.0 - Added by PITUS-16 project | Magnesium red cell 18 RBC 390982006 | Red cell magnesium measurement | 3.0 3.0 - Added by PITUS-16 project Magnesium urine Urine Magnesium; Urine Mg 15 Urine 35391003 | Magnesium measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Magnesium urine 24h 24 hr urine Magnesium; Magnesium 24 hour 19 24 hr urine 313675002 | 24 hour urine magnesium output 3.0 3.0 - Changed preferred term from 'Magnesium 24 hr urine' urine; 24hr Urine Mg measurement | 2.0 - Added by PITUS-14 Working group 2 Malaria Ag Malaria POCT; Malaria Point of Care test 10 Whole Blood 407727009 | Malaria antigen test | 3.0 3.0 - Added by PITUS-16 project Malaria screen Malaria; MP screen; Malarial studies 14 Whole blood 171140005 | Malaria screening | 2.0 2.0 - Added by PITUS-14 Working group 2 Malaria thick film Thick film 18 Whole blood 121240000 | Malaria thick smear | 1.0 1.0 - Added by PUTS project Manganese Mn 10 Whole blood 415845007 | Whole blood manganese measurement | 2.0 2.0 - Added by PITUS-14 Working group 2

Manganese plasma Mn 16 Plasma 391529001 | Plasma manganese level | 2.0 2.0 - Added by PITUS-14 Working group 2 Manganese urine Urine Manganese; Urine Mn 15 Urine 33959006 | Manganese measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Manganese urine 24h 19 Urine 733891000168106 | Manganese measurement, 24 3.0 3.0 - Added by PITUS-16 project hour urine | Marburg virus Ab Marburg virus antibodies; Arenavirus 16 838331000168109 | Marburgvirus antibody 3.0 3.0 - Added by PITUS-16 project measurement | Marburg virus nucleic acid Marburg virus PCR; Marburg virus RNA; 26 841781000168102 | Marburgvirus nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project Arenavirus Maternal Downs screening test Triple test 29 315115008 | Downs screening test | 1.0 1.0 - Added by PUTS project MCS Microscopy culture sensitivities; MCS 3 168132005 | Microscopy, culture and sensitivities | 1.0 1.0 - Added by PUTS project

MCS bronchoalveolar lavage and/or wash MCS respiratory; MCS bronchoalveolar 38 844871000168105 | Bronchoalveolar lavage 3.0 3.0 - Added by PITUS-16 project lavage; Bronchial brush wash; microscopy, culture and sensitivities | Bronchoalveolar lavage microscopy and culture MCS CSF Cerbrospinal fluid MCS; Microscopy culture 7 CSF 401035006 | Cerebrospinal fluid microscopy culture 1.0 1.0 - Added by PUTS project sensitivities CSF and sensitivities | MCS ear Ear microscopy, culture and sensitivities ; Ear 7 838301000168102 | Ear microscopy, culture and 3.0 3.0 - Added by PITUS-16 project swab sensitivities | MCS faeces Enteric microscopy culture and sensitivities; 10 738111000168104 | Faeces microscopy, culture and 3.0 3.0 - Added by PITUS-16 project MCS enteric; Faeces microscopy culture and sensitivities | sensitivities; Faeces MCS OCP

MCS fluid MCS Synovial fluid; MCS Ascitic fluid; MCS PD 9 Fluid 401325009 | Fluid microscopy, culture and sensitivities 3.0 3.0 - Added by PITUS-16 project fluid; MCS Pleural fluid | MCS fungal Fungal MCS; Mycology; Skin scrapings; Nail 10 Any 401285009 | Mycology microscopy, culture and 3.0 3.0 - Added synonyms 'Nail clippings; MCS fungal and antigen' clippings; MCS fungal and antigen sensitivities | 1.0 - Added by PUTS project

MCS genital Genital MCS; Microscopy culture sensitivities 11 401287001 | Genital microscopy, culture and 1.0 1.0 - Added by PUTS project Urogenital MCS sensitivities | MCS Mycobacteria AFB; TB Microscopy culture sensitivities; 16 Sputum 401274007 | Mycobacteria microscopy, culture and 3.0 3.0 - Amalgamated 'Mycobacteria culture' with 'MCS Mycobacteria' Mycobacteria culture; Mycobacterium sensitivities | and added synonyms 'Mycobacteria culture; Mycobacterium tuberculosis culture; TB culture tuberculosis culture; TB culture' 1.0 - Added by PUTS project MCS respiratory MCS Respiratory 15 401288006 | Respiratory microscopy, culture and 1.0 1.0 - Added by PUTS project sensitivities | MCS sputum Sputum culture 10 104173009 | Microbial culture of sputum | 3.0 3.0 - Added by PITUS-16 project MCS tissue MCS tissue 10 41243006 | Microbial culture, tissue | 3.0 3.0 - Added by PITUS-16 project MCS urine Urine microscopy culture and sensitivities; 10 Urine 401324008 | Urinary microscopy, culture and 3.0 3.0 - Added synonym 'Antenatal screen' UMCS; UMC; Urine MCS; Antenatal screen sensitivities | 1.0 - Added by PUTS project

MCS wound Wound MCS; Wound Microscopy culture 9 401294003 | Wound microscopy, culture and 1.0 1.0 - Added by PUTS project sensitivities sensitivities | Mean cell volume MCV; Erythrocyte mean corpuscular volume 16 Whole blood 104133003 | Erythrocyte mean corpuscular volume 1.0 1.0 - Added by PUTS project determination | Measles Ag Measles antigen 10 Serum 398518009 | Measles antigen assay | 2.0 2.0 - Added by PITUS-14 Working group 2 Measles IgG 11 Serum 315149000 | Measles IgG level | 2.0 2.0 - Added by PITUS-14 Working group 2 Measles IgM 11 Serum 315150000 | Measles IgM level | 2.0 2.0 - Added by PITUS-14 Working group 2 Measles nucleic acid Measles PCR 20 767771000168103 | Measles nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project Measles serology Measles antibodies; Measles IgG and IgM; 16 Serum; CSF 104325006 | Measurement of Measles virus antibody | 3.0 3.0 - Added by PITUS-16 project Measles immunity Meningococcal nucleic acid Meningococcal PCR; Neisseria meningitidis 27 Blood; CSF 398405003 | Meningococcal nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project PCR; Neisseria meningitidis nucleic acid

Mercury Hg 7 Whole blood 23529001 | Mercury measurement, blood | 2.0 2.0 - Added by PITUS-14 Working group 2 Mercury urine Urine Mercury; Urine Hg 13 Urine 34924001 | Mercury measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Mercury urine 24h 24 hr urine Mercury; Mercury 24 hour urine; 17 24 hr urine 313594000 | Mercury measurement, 24H urine | 3.0 3.0 - Changed preferred term from 'Mercury 24 hr urine' Hg 24 hr urine 2.0 - Added by PITUS-14 Working group 2 MERS-CoV nucleic acid Middle East Respiratory Syndrome 21 841931000168101 | Middle East respiratory syndrome 3.0 3.0 - Added by PITUS-16 project coronavirus PCR; MERS-CoV PCR; coronavirus nucleic acid assay | Coronavirus Metanephrine urine 24h Urine Metanephrine; Urine 22 24 hr urine 27854006 | Metanephrines measurement, total, urine 3.0 3.0 - Changed from preferred term from 'Metanephrine 24 hr urine' NorMetanephrines | 2.0 - Added by PITUS-14 Working group 2

Methaemoglobin MetHb 14 Whole blood 441965001 | Measurement of methaemoglobin | 2.0 2.0 - Added by PITUS-14 Working group 2 Methamphetamine urine 21 Urine 313579004 | Urine methamphetamine measurement | 2.0 2.0 - Added by PITUS-14 Working group 2

Methotrexate MTX 12 Serum 313827005 | Serum methotrexate measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Methylhistamine urine 21 24 hr urine 313610004 | Urine N-methyl histamine measurement 3.0 3.0 - Added by PITUS-16 project | MIC susceptibility MIC, Minimum inhibitory concentration - 19 16151007 | Microbial identification and susceptibility 3.0 3.0 - Added by PITUS-16 project bacterial isolate test | Microalbumin Albumin:creatinine ratio; MCR; ACR; Urine 13 Urine 271075006 | Urine albumin/creatinine ratio 3.0 3.0 - Added synonym 'Urine ACR' ACR measurement | 1.0 - Added by PUTS project Microscopy urine Urine microscopy 16 Urine 127800008 | Microscopic urinalysis | 1.0 1.0 - Added by PUTS project

Page 9 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History Mitochondrial Ab Mitochondrial antibodies; AMA 16 Serum 314092004 | Mitochondrial antibody screening test | 2.1 2.1 - Changed preferred term from 'Mitochondrial antibodies' 2.0 - Added by PITUS-14 Working group 2 Morphine level 14 Serum 313794002 | Serum morphine measurement | 3.0 3.0 - Added by PITUS-16 project MRSA screening Methicillin resistant Staphylococcus aureus 14 301786007 | Multi-resistant staphylococcus aureus 3.0 3.0 - Changed preferred term from 'MRSA screen' and added screen; Multi-resistant Staphylococcus screening | synonym 'Infection control screening' aureus screen; MRSA; MRSA Staphylococcus 2.0 - Added by PITUS-14 Working group 2 aureus screen; Infection control screening

Mucopolysaccharides 19 104461000 | Acid mucopolysaccharides measurement, 3.0 3.0 - Added by PITUS-16 project quantitative | Mumps Ab Mumps serology 8 Serum 315159004 | Mumps antibody level | 2.0 2.0 - Added by PITUS-14 Working group 2 Mumps Ag Mumps antigen 8 Serum 122355008 | Mumps virus antigen assay | 2.0 2.0 - Added by PITUS-14 Working group 2 Mumps IgG Mumps antibody; Mumps immunity; Mumps 9 Serum 315155005 | Mumps IgG level | 2.0 2.0 - Added by PITUS-14 Working group 2 immune screen Mumps IgM Mumps antibody 9 Serum 315156006 | Mumps IgM level | 2.0 2.0 - Added by PITUS-14 Working group 2 Murray Valley encephalitis nucleic acid Murray Valley encephalitis virus nucleic acid, 39 Serum; CSF 767781000168100 | Murray Valley encephalitis nucleic 3.0 3.0 - Added by PITUS-16 project Arbovirus nucleic acid; Murray Valley acid assay | encephalitis virus PCR Murray Valley encephalitis virus Ab Murray Valley encephalitis virus antibody, 35 Serum 443107000 | Measurement of Murray Valley 3.0 3.0 - Added by PITUS-16 project Arbovirus antibody encephalitis virus antibody | MUSK Ab Muscle specific receptor tyrosine kinase Ab; 7 Serum 414787008 | Anti MuSK antibody level | 3.0 3.0 - Added by PITUS-16 project Muscle specific receptor tyrosine kinase antibodies; Muscle specific kinase antibodies; Myasthenia antibodies; Myasthenia gravis antibodies

Mycobacteria culture 20 3.0 3.0 - Deleted 'Mycobacteria culture', now refer to MCS Mycobacteria 1.0 - Added by PUTS project Mycobacterium tuberculosis IGRA IGRA Mycobacterium tuberculosis; Interferon- 31 Sputum; 766111000168105 | Mycobacterium tuberculosis 3.0 3.0 - Added by PITUS-16 project Gamma assay for Mycobacterium Bronchoscopy interferon-gamma release assay | tuberculosis brushing, lavage; Tissue biopsy; Body fluids (eg, CSF, pleural, synovial, pericardial fluids); Pus; Urine; Blood culture; Bone marrow aspirate; Faeces

Mycophenolate Mycophenolic acid; Cellcept; MMF; Mofetil 13 Blood 439261002 | Measurement of mycophenolic acid | 2.0 2.0 - Added by PITUS-14 Working group 2

Mycoplasma Ab Mycoplasma screen; Mycoplasma 13 Serum 104291008 | Measurement of Mycoplasma species 2.0 2.0 - Added by PITUS-14 Working group 2 pneumonia serology; Mycoplasma serology antibody |

Mycoplasma IgG 14 Serum 313705006 | Mycoplasma IgG measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Mycoplasma IgM 14 Serum 313689007 | Mycoplasma IgM measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Mycoplasma nucleic acid Mycoplasma PCR 23 122410002 | Mycoplasma pneumoniae DNA assay | 2.0 2.0 - Added by PITUS-14 Working group 2

Mycoplasma pneumoniae Ab Mycoplasma pneumoniae serology 24 Serum 122048000 | Measurement of Mycoplasma 1.0 1.0 - Added by PUTS project pneumoniae antibody | Myelin basic protein Ab 23 Serum 117912005 | Measurement of myelin basic protein 3.0 3.0 - Added by PITUS-16 project antibody | Myeloperoxidase Ab MPO; ANCA; Anti neutrophil cytoplasmic 18 Serum 118092009 | Measurement of myeloperoxidase 3.0 3.0 - Added by PITUS-16 project antibodies antibody | Myocardial Ab Myocardial antibodies 13 Serum 313614008 | Myocardial antibody measurement | 3.0 3.0 - Added by PITUS-16 project Myoglobin random urine qualitative 34 439900008 | Qualitative measurement of myoglobin in 3.0 3.0 - Added by PITUS-16 project urine | Myoglobin urine 15 Urine 32375007 | Myoglobin measurement, urine | 3.0 3.0 - Added by PITUS-16 project Nasal bacterial culture Nasopharyngeal swab/aspirate; Nasal swab; 23 843491000168106 | Nasal bacterial culture | 3.0 3.0 - Added by PITUS-16 project MCS nose; Nose microscopy, culture and sensitivities Neisseria gonorrhoea nucleic acid Gonorrhoea PCR; Neisseria gonorrhoea NAD; 33 398381009 | Neisseria gonorrhoeae nucleic acid 1.0 1.0 - Added by PUTS project Neisseria gonorrhoea PCR detection | Neisseria meningitidis serology Neisseria meningitidis antibody 31 104292001 | Measurement of Neisseria meningitidis 3.0 3.0 - Added by PITUS-16 project antibody | Neuronal Ab Neuronal antibodies; Paraneoplastic 11 Serum 117917004 | Measurement of neuronal antinuclear 3.0 3.0 - Added by PITUS-16 project neurologic antibodies; Cerebellar IIF; ANNA; antibody | Antineuronal nuclear antibodies Neuron-specific enolase NSE 23 Serum 35785002 | Neuron-specific enolase measurement | 2.0 2.0 - Added by PITUS-14 Working group 2

Neutrophil function studies 27 Plasma 166162008 | Neutrophil function test | 3.0 3.0 - Added by PITUS-16 project Nickel urine Urine Nickel; Urine Ni 12 Urine 391351008 | Urine nickel level | 2.0 2.0 - Added by PITUS-14 Working group 2 Nickel urine 24h Nickel 24 hour urine; 24 hr urine Nickel 16 24 hr urine 391358002 | 24 hour urine nickel output | 3.0 3.0 - Chnaged preferred term from 'Nickel 24 hr urine' 2.0 - Added by PITUS-14 Working group 2 Nipah virus Ab Nipah virus antibodies 14 Serum 838361000168101 | Nipah virus antibody 3.0 3.0 - Added by PITUS-16 project measurement | Nipah virus nucleic acid Nipah virus PCR 24 841941000168105 | Nipah virus nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project

NMDA receptor Ab N-methyl-D-aspartate receptor antibodies; 16 Serum; CSF 445362000 | Measurement of N-methyl-D-aspartate 3.0 3.0 - Added by PITUS-16 project NMDA receptor antibodies; NMDA-R receptor antibody | antibodies Non HDL Cholesterol 19 Serum 828471000168102 | Non-HDL cholesterol 3.0 3.0 - Added by PITUS-16 project measurement | Noradrenaline urine Urine Noradrenaline 19 Urine 271250000 | Urine noradrenaline measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Noradrenaline urine 24h Noradrenaline 24 hour urine; 24 hr urine 23 24 hr urine 313552003 | 24 hour urine noradrenaline output 3.0 3.0 - Changed preferred term from 'Noradrenaline 24 hr urine' Noradrenaline measurement | 2.0 - Added by PITUS-14 Working group 2

Normetanephrine 15 Plasma 104835007 | Normetadrenaline measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Normetanephrine urine 21 Urine 390973000 | Urine normetadrenaline level | 2.0 2.0 - Added by PITUS-14 Working group 2 Normetanephrine urine 24h Normetanephrine 24 hour urine; 24 hour 25 24 hr urine 390947005 | 24 hour urine normetadrenaline output | 3.0 3.0 - Changed preferred term from 'Normetanephrine 24 hr urine' urine Normetanephrine 2.0 - Added by PITUS-14 Working group 2

Nortriptyline 13 Serum 395042000 | Serum nortriptyline level | 2.0 2.0 - Added by PITUS-14 Working group 2 N-Telopeptides urine Urine N-Telopeptides; Hydoxyproline 20 Urine 397605005 | Urine N-telopeptide cross links 2.0 2.0 - Added by PITUS-14 Working group 2 measurement | N-Telopeptides urine 24h N-Telopeptides 24 hour urine; 24 hr urine N- 24 24 hr urine 444220002 | Quantitative measurement of collagen 3.0 3.0 - Changed preferred term from 'N-Telopeptides 24 hr urine' Telopeptides cross linked N-telopeptide in 24 hour urine specimen | 2.0 - Added by PITUS-14 Working group 2

NT-proBNP N terminal pro-brain natriuretic peptide 9 Serum 414799001 | N terminal pro-brain natriuretic peptide 3.0 3.0 - Added synonym 'NTproBNP' level; NT-proBNP; NTproBNP level | 2.0 - Added by PITUS-14 Working group 2 Occult blood faeces FOB; FOBT; Faecal occult blood 19 Faeces 442516004 | Measurement of occult blood in three 3.0 3.0 - Added synonym 'FOBT' separate stool specimens | 1.0 - Added by PUTS project Oestradiol E2; Estradiol 10 Serum 166448005 | Serum oestradiol measurement | 1.0 1.0 - Added by PUTS project Oestriol Estriol 8 Serum 34889009 | Oestriol measurement | 3.0 3.0 - Added by PITUS-16 project Oestrone 8 Serum 104657002 | Oestrone measurement | 3.0 3.0 - Added by PITUS-16 project Oligoclonal banding Serum oligoclonal bands 19 Serum 41489001 | Oligoclonal protein measurement | 2.1 2.1 - Changed preferred term from ‘Oligoclonal Banding’ 2.0 - Added by PITUS-14 Working group 2 Opiates urine Urine Opiates 13 Urine 314083002 | Urine opiates screening test | 2.0 2.0 - Added by PITUS-14 Working group 2 Organic acids urine 19 Urine 104838009 | Organic acids measurement | 3.0 3.0 - Added by PITUS-16 project Osmolality 10 Serum 44628004 | Osmolality measurement, serum | 1.0 1.0 - Added by PUTS project Osmolality urine Urine Osmolality 16 Urine 78888000 | Osmolality measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Osmolar gap Osm Gap 11 Serum 104433006 | Osmolar gap measurement, serum | 2.1 2.1 - Changed preferred term from 'Osmolar Gap' 2.0 - Added by PITUS-14 Working group 2 Osmolar gap urine Urine Osmolar Gap; Urine Osm Gap 17 Urine 104432001 | Osmolar gap measurement, urine | 2.1 2.1 - Changed preferred term from 'Osmolar Gap urine' 2.0 - Added by PITUS-14 Working group 2 Osteocalcin 11 Serum 104844008 | Osteocalcin measurement | 3.0 3.0 - Added by PITUS-16 project Ova cysts parasites faeces OCP; Faeces OCP; Faeces MCS OCP 26 Faeces 250462009 | Count of ova cysts and parasites | 3.0 3.0 - Added synonyms 1.0 - Added by PUTS project Ovarian Ab Ovarian antibodies; Adrenal antibodies; 17- 10 Serum 117923009 | Measurement of ovary antibody | 3.0 3.0 - Added by PITUS-16 project Hydroxylase antibodies; 17-OH antibodies; 21-Hydroxylase antibodies; 21-OH antibodies

Oxalate 7 Plasma 408188008 | Plasma oxalate level | 3.0 3.0 - Added by PITUS-16 project Oxalate urine 13 24 hr urine 313945009 | 24 hour urine oxalate output 3.0 3.0 - Added by PITUS-16 project measurement | Oxyhaemoglobin 14 Whole blood 104848006 | Oxyhaemoglobin, total measurement | 2.0 2.0 - Added by PITUS-14 Working group 2

Pancreatic elastase faeces 26 Faeces 390953005 | Faecal elastase 1 level | 3.0 3.0 - Added by PITUS-16 project Pancreatic polypeptide 22 Serum 55131002 | Pancreatic polypeptide measurement | 3.0 3.0 - Added by PITUS-16 project

Pap smear Cytology cervical; Cytology gynae; Cervical 9 440623000 | Microscopic examination of cervical 1.0 1.0 - Added by PUTS project cytology; Cytology pap smear; Pap Papanicolaou smear |

Paracetamol level Acetaminophen level 17 Serum 46093004 | Paracetamol measurement | 1.0 1.0 - Added by PUTS project

Page 10 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History Paraprotein concentration Paraprotein 25 Serum 166793003 | Serum paraprotein measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Paraprotein concentration urine Urine Paraprotein concentration; Bence- 31 Urine 167460003 | Urine paraprotein measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Jones protein;BJP Paraprotein concentration urine 24h Paraprotein concentration 24 hour urine; 24 35 24 hr urine 412806009 | 24 hour urine paraprotein output | 3.0 3.0 - Changed preferred term from 'Paraprotein concentration 24 hr hour urine Paraprotein concentration; 24 urine' hour Bence-Jones protein 2.0 - Added by PITUS-14 Working group 2 Paraprotein typing 18 Serum 315165004 | Paraprotein typing by immunofixation | 3.0 3.0 - Added by PITUS-16 project

Parathyroid Ab Parathyroid antibodies 14 Serum 313510008 | Parathyroid antibody measurement | 3.0 3.0 - Added by PITUS-16 project

Parathyroid hormone PTH; Parathyroid hormone - intact; Intact 19 Serum 271541003 | Serum parathyroid hormone 1.0 1.0 - Added by PUTS project parathyroid hormone measurement | Parathyroid hormone related protein PTHrP, PTH-related protein 35 Plasma 401154008 | Plasma parathyroid hormone related 3.0 3.0 - Added by PITUS-16 project peptide measurement | Parietal cell Ab Parietal cell antibodies; GPC Ab; Gastric 16 Serum 30521008 | Antibody to gastric parietal cell 3.0 3.0 - Added by PITUS-16 project parietal cell antibodies; PCA measurement | Parvovirus Ab Parvovirus serology 13 Serum 104324005 | Measurement of Parvovirus antibody | 1.0 1.0 - Added by PUTS project

Parvovirus B19 Ab Parvovirus B19 Ab 17 Serum 117855005 | Measurement of Human parvovirus B19 1.0 1.0 - Added by PUTS project antibody | Parvovirus B19 nucleic acid Measles PCR 27 Serum 398585004 | Parvovirus B19 nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project Parvovirus IgG 14 Serum 313577002 | Human parvovirus IgG measurement | 2.0 2.0 - Added by PITUS-14 Working group 2

Parvovirus IgM 14 Serum 313701002 | Human parvovirus IgM measurement | 2.0 2.0 - Added by PITUS-14 Working group 2

PCA-2 Ab Neuronal antibodies; Paraneoplastic 8 Serum, CSF 117931004 | Measurement of Purkinje cell antibody | 3.0 3.0 - Added by PITUS-16 project neurologic antibodies; Cerebellar IIF; ANNA; Antineuronal nuclear antibodies; Purkinje cell antibodies PCNA extractable nuclear Ab ENA; PCNA 27 Serum 66408003 | Antibody to PCNA measurement | 3.0 3.0 - Added by PITUS-16 project pCO2 blood gas Blood Gas pCO2 14 167028004 | Measurement of arterial partial pressure 2.0 2.0 - Added by PITUS-14 Working group 2 of carbon dioxide | pH blood gas Blood Gas pH 12 27051004 | pH measurement, arterial | 2.0 2.0 - Added by PITUS-14 Working group 2 pH faeces 9 Faeces 167671009 | Measurement of faeces pH | 3.0 3.0 - Added by PITUS-16 project pH urine 8 Urine 167305006 | Urine pH test | 3.0 3.0 - Added by PITUS-16 project pH venous 9 Whole Blood 9456006 | pH measurement, venous | 3.0 3.0 - Added by PITUS-16 project Phenobarbitone level Phenobarb; Phenobarbital; Methyl 20 Serum 269866007 | Serum phenobarbitone measurement | 2.1 2.1 - Changed preferred term from 'Phenobarbitone' Phenobarbitone 2.0 - Added by PITUS-14 Working group 2 Phenytoin level Dilantin level 15 Serum 269867003 | Serum phenytoin measurement | 1.0 1.0 - Added by PUTS project Phenytoin level free Free dilantin level 20 105298007 | Phenytoin, free measurement | 3.0 3.0 - Added by PITUS-16 project Phosphate PO4; PHOS 9 Serum 271241002 | Serum inorganic phosphate 1.0 1.0 - Added by PUTS project measurement | Phosphate urine Urine Phosphate; Urine PO4 15 Urine 271262001 | Urine inorganic phosphate measurement 2.0 2.0 - Added by PITUS-14 Working group 2 | Phosphate urine 24h Phosphate 24 hour urine; 24 hr urine 19 24 hr urine 313935007 | 24 hour urine phosphate output 3.0 3.0 - Changed preferred term from 'Phosphate 24 hr urine' Phosphate; PO4 24 hour urine; 24 hr urine measurement | 2.0 - Added by PITUS-14 Working group 2 PO4 Phytanate 9 Serum; Plasma 61241003 | Phytanate measurement | 3.0 3.0 - Added by PITUS-16 project Pipecolic acid urine 20 Urine 428035006 | Measurement of pipecolic acid | 3.0 3.0 - Added by PITUS-16 project Plasminogen activator inhibitor PAI 31 Plasma 58543006 | Plasminogen activator inhibitor assay | 3.0 3.0 - Added by PITUS-16 project

Platelet Ab detection Platelet antibodies 21 79623001 | Antibody detection, platelet antibody | 3.0 3.0 - Added by PITUS-16 project

Platelet aggregometry Platelet aggregation test 21 19739004 | Platelet aggregation test | 3.0 3.0 - Added by PITUS-16 project Platelet count PLT 14 Whole blood 61928009 | Platelet count | 1.0 1.0 - Added by PUTS project Platelet function test Platelet function studies 22 Blood 80329005 | Platelet function test | 2.1 2.1 - Changed preferred term from 'Platelet Function test' 2.0 - Added by PITUS-14 Working group 2 Platelet serotonin release assay Serotonin platelet 32 87532009 | Serotonin release assay for platelet 3.0 3.0 - Added by PITUS-16 project antibody | PM-Scl Ab Polymyositis-scleroderma extractable nuclear 9 Serum 122228002 | Measurement of polymyositis- 3.0 3.0 - Added by PITUS-16 project antibodies; PM-1 antibodies scleroderma extractable nuclear antibody | Pneumococcal Ab 15 313632008 | Pneumococcal antibody measurement | 3.0 3.0 - Added by PITUS-16 project

PNH screen Flow cytometry for PNH; PNH surface 10 408595009 | Paroxysmal nocturnal haemoglobinuria 3.0 3.0 - Added by PITUS-16 project markers; Paroxysmal nocturnal cell marker analysis | haemoglobinuria cell markers; GPI linked proteins pO2 blood gas Blood Gas pO2 13 25579001 | Oxygen measurement, partial pressure, 2.0 2.0 - Added by PITUS-14 Working group 2 arterial | Porphobilinogen deaminase 25 391407003 | Blood erythrocyte PBG deaminase level | 3.0 3.0 - Added by PITUS-16 project

Porphobilinogen synthetase ALA dehydratase; Aminolaevulinic acid 26 5586008 | Aminolevulinic acid dehydratase 3.0 3.0 - Added by PITUS-16 project dehydratase measurement | Porphobilinogen urine 21 104882000 | Porphobilinogen measurement | 1.0 1.0 - Added by PUTS project Porphyrin faeces Faecal porphyrin; Total faecal porphyrin 16 Spot faeces 10 g 89900006 | Porphyrin measurement, faeces, 3.0 3.0 - Added by PITUS-16 project quantitative | Porphyrin plasma 16 Plasma 313789002 | Plasma porphyrin measurement | 3.0 3.0 - Added by PITUS-16 project Porphyrin screen Porphyrin tests; Porphyrins and precursors 16 Blood; Urine; 252159009 | Porphyrin screening | 3.0 3.0 - Added by PITUS-16 project Faeces Porphyrin urine Total urine porphyrin 15 Urine 22031009 | Porphyrin, quantitative measurement, 3.0 3.0 - Added by PITUS-16 project urine | Potassium K 9 Serum 271236005 | Serum potassium measurement | 1.0 1.0 - Added by PUTS project Potassium urine Urine Potassium; Urine K 15 Urine 49833001 | Potassium measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Potassium urine 24h Potassium 24 hour urine; 24 hr urine 19 24 hr urine 313658008 | 24 hour urine potassium output 3.0 3.0 - Changed preferred term from 'Potassium 24 hr urine' Potassium; 24 hr Urine K; K 24 hour urine measurement | 2.0 - Added by PITUS-14 Working group 2 Prealbumin 10 Serum 395043005 | Serum prealbumin level | 2.0 2.0 - Added by PITUS-14 Working group 2 Pregnancy test Beta HCG qualitative screen 14 Serum 166434005 | Serum pregnancy test (B-HCG) | 1.0 1.0 - Added by PUTS project Primidone 9 Serum 113087005 | Primidone measurement | 3.0 3.0 - Added by PITUS-16 project Procainamide 12 Serum 59014001 | Procainamide measurement | 3.0 3.0 - Added by PITUS-16 project Procalcitonin PCT 14 Serum 738211000168109 | Procalcitonin measurement, 3.0 3.0 - Added by PITUS-16 project serum | Procollagen type 1 N-terminal propeptide P1NP 40 Serum 416399002 | Procollagen type I amino-terminal 3.0 3.0 - Added by PITUS-16 project propeptide level | Progesterone Prog; P4 12 Serum 270972001 | Serum progesterone measurement | 1.0 1.0 - Added by PUTS project Proinsulin 11 Serum 104890000 | Proinsulin measurement | 3.0 3.0 - Added by PITUS-16 project Prolactin 9 Serum 313442000 | Serum prolactin measurement | 1.0 1.0 - Added by PUTS project Properdin factor B 18 Serum 104367002 | Properdin factor B measurement | 3.0 3.0 - Added by PITUS-16 project Prostate specific antigen PSA; Prostate specific antigen total 25 Serum; Plasma 63476009 | Prostate specific antigen measurement | 1.0 1.0 - Added by PUTS project

Protein Total protein; TP 7 Serum 270992008 | Serum total protein measurement | 1.0 1.0 - Added by PUTS project Protein C 9 Platelet poor 48627002 | Protein C, assay | 1.0 1.0 - Added by PUTS project plasma Protein CSF Cerebrospinal fluid Total protein; CSF Total 11 CSF 84130004 | Measurement of protein in cerebrospinal 2.0 2.0 - Added by PITUS-14 Working group 2 Protein; cerebrospinal fluid Protein; CSF fluid specimen | Protein Protein electrophoresis EPG; EPP; SPE; Protein EPG 23 Serum 4903000 | Serum protein electrophoresis | 3.0 3.0 - Added synonym 'Protein EPG' 1.0 - Added by PUTS project Protein electrophoresis CSF Cerebrospinal fluid oligoclonal bands; CSF 27 CSF 113073005 | Cerebrospinal fluid oligoclonal bands | 2.1 2.1 - Changed preferred term from ‘Oligoclonal Banding CSF’; Added oligoclonal bands; MS Screen; Oligoclonal synonym 'OCB' Bands; OCB 2.0 - Added by PITUS-14 Working group 2 Protein electrophoresis urine Protein EPG; Urine EPG; UEPG; UEPP; Bence 29 Random urine 73718004 | Urine protein electrophoresis | 3.0 3.0 - Added by PITUS-16 project Jones protein; BJP Protein S 9 Platelet poor 20469004 | Protein S assay | 1.0 1.0 - Added by PUTS project plasma Protein urine Urine protein; Urine Pr; Protein excretion 14 Urine 171247004 | Urine screening for protein | 2.0 2.0 - Added by PITUS-14 Working group 2

Protein urine 24h Urine protein 24 Hour; 24 hr Urine Protein; 17 24 hr urine 19518008 | Protein measurement, urine, quantitative 3.0 3.0 - Changed preferred term from 'Protein 24 hr urine' Urine Pr 24 Hour; 24 hr Urine Pr 24 hour | 2.0 - Added by PITUS-14 Working group 2 Protein urine random Urine protein/creatine ratio; Urine 20 Random urine 313500004 | Urine protein/creatinine ratio 3.0 3.0 - Added synonym 'Urine Protein/Cr' Protein/Cr measurement | 1.0 - Added by PUTS project Proteinase 3 Ab PR3; PR3 Ab; Anti neutrophil cytoplasmic 15 Serum 117987007 | Measurement of proteinase 3 antibody | 3.0 3.0 - Added by PITUS-16 project antibodies Prothrombin time PT 16 Plasma 396451008 | Prothrombin time | 1.0 1.0 - Added by PUTS project Pyruvate 8 Plasma 391501004 | Plasma pyruvate level | 3.0 3.0 - Added by PITUS-16 project Pyruvate kinase 15 30481007 | Pyruvate kinase measurement | 3.0 3.0 - Added by PITUS-16 project Q Fever Ab Coxiella burnetti Ab; Q Fever serology 10 Serum 315105002 | Coxiella burnetii antibody level | 1.0 1.0 - Added by PUTS project Q Fever IgG Coxiella burnetii IgG 11 Serum 134259006 | Coxiella burnetii IgG level | 2.0 2.0 - Added by PITUS-14 Working group 2 Q Fever IgM Coxiella burnetii IgM 11 Serum 134258003 | Coxiella burnetii IgM level | 2.0 2.0 - Added by PITUS-14 Working group 2 Q fever nucleic acid Q fever PCR; Coxiella burnetii nucleic acid; 20 838401000168105 | Coxiella burnetii nucleic acid assay 3.0 3.0 - Added by PITUS-16 project Coxiella burnetii PCR | Quinidine 9 Serum 82650003 | Quinidine measurement | 3.0 3.0 - Added by PITUS-16 project Rabies virus Ab Lyssa virus 15 Blood; CSF 122078009 | Measurement of Rabies virus antibody | 3.0 3.0 - Added by PITUS-16 project

Rabies virus nucleic acid Rabies virus PCR 25 841961000168109 | Rabies virus nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project

RAST Allergy screening test 4 Serum 395142003 | Allergy screening test | 1.0 1.0 - Added by PUTS project Reducing substances faeces 26 Faeces 252169003 | Faecal reducing substance screening | 1.0 1.0 - Added by PUTS project

Page 11 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History Renin 5 Plasma 391479001 | Plasma renin level | 1.0 1.0 - Added by PUTS project Respiratory syncytial virus Ag Respiratory syncytial virus antigen; RSV Ag; 30 Nasopharyngeal 315184001 | RSV antigen level | 3.0 3.0 - Added by PITUS-16 project RSV antigen aspirate or swab Respiratory syncytial virus culture RSV culture 35 122274003 | Respiratory syncytial virus culture | 3.0 3.0 - Added by PITUS-16 project Respiratory syncytial virus nucleic acid RSV nucleic acid 40 839431000168105| Respiratory syncytial virus nucleic 3.0 3.0 - Added by PITUS-16 project acid assay | Reticulocyte count Retics 18 Whole blood 45995003 | Reticulocyte count | 2.0 2.0 - Added by PITUS-14 Working group 2 Reverse T3 10 Serum 51583006 | T3 reverse measurement | 3.0 3.0 - Added by PITUS-16 project Rheumatoid factor RF 17 Serum 54921001 | Rheumatoid factor measurement | 1.0 1.0 - Added by PUTS project Rhinovirus nucleic acid Rhinovirus RNA 23 122418009 | Rhinovirus RNA assay | 3.0 3.0 - Added by PITUS-16 project Ri Ab Neuronal antibodies; Paraneoplastic 5 Serum; CSF 394709003 | Ri antibody level | 3.0 3.0 - Added by PITUS-16 project neurologic antibodies; Cerebellar IIF; ANNA; ANNA-2; Antineuronal nuclear antibodies; Type 2 anti-neuronal nuclear antibody

Ricin toxin Ricinus communis (castor beans) 11 838371000168107 | Ricin toxin detection | 3.0 3.0 - Added by PITUS-16 project Rickettsia typhus group Ab Queensland Tick Typhus; Flinders Island 27 122081004 | Measurement of typhus group rickettsia 3.0 3.0 - Added by PITUS-16 project Spotted Fever; Rickettsia australis; Rickettsia antibody | honei; Rickettsia typhi (murine typhus); Orientia tsutsugamushi (Scrub typhus); Rickettsia prowazekii (Epidemic typhus fever)

Rickettsia typhus group nucleic acid Queensland Tick Typhus; Flinders Island 36 847031000168109 | Typhus group rickettsia nucleic 3.0 3.0 - Added by PITUS-16 project Spotted Fever; Rickettsia australis; Rickettsia acid assay | honei; Rickettsia typhi (murine typhus); Orientia tsutsugamushi (Scrub typhus); Rickettsia prowazekii (Epidemic typhus fever)

Rickettsial Ab Rickettsial serology 14 Serum 47919007 | Rickettsial serologic study | 2.0 2.0 - Added by PITUS-14 Working group 2 Rickettsial culture 19 122215009 | Rickettsia species culture | 3.0 3.0 - Added by PITUS-16 project Rickettsial nucleic acid Rickettsia species nucleic acid 24 838381000168105 | Rickettsia species nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | Ristocetin cofactor Factor VIII R: R Co assay 20 Plasma 15356000 | Factor VIII R: R Co assay | 3.0 3.0 - Added by PITUS-16 project Ristocetin-induced platelet aggregation 39 Plasma 103843005 | Platelet aggregation with ristocetin test | 3.0 3.0 - Added by PITUS-16 project

RNP Ab ENA; Ribonucleoprotein extractable nuclear 7 Serum 166008006 | RNP antibody measurement | 3.0 3.0 - Added by PITUS-16 project antibodies; U1RNP Ross River virus Ab RRV Ab; Ross River virus serology; Arbovirus 19 Serum 315186004 | Ross River virus antibody level | 3.0 3.0 - Added synonym 'Arbovirus antibody' antibody 1.0 - Added by PUTS project Ross River virus nucleic acid RRV nucleic acid; Arbovirus nucleic acid 29 839391000168100 | Ross River virus nucleic acid assay 3.0 3.0 - Added by PITUS-16 project | Rotavirus Ag faeces 19 Faeces 4691008 | Identification of rotavirus antigen in faeces 1.0 1.0 - Added by PUTS project | RPR Rapid plasma reagin 3 Plasma 19869000 | Rapid plasma reagin test | 1.0 1.0 - Added by PUTS project Rubella Ab Rubella serology; Antenatal screen 10 Serum 252409009 | Rubella antibody screening | 3.0 3.0 - Added synonym ' Antenatal screen' 1.0 - Added by PUTS project Rubella IgG Rub IgG Ab; Rubella immunity 11 Serum 313670007 | Rubella IgG measurement | 3.0 3.0 - Changed preferred term from 'Rubella IgG Ab' 1.0 - Added by PUTS project Rubella IgM 11 Serum 313479002 | Rubella IgM measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Salicylate Aspirin 10 Serum 36206007 | Salicylate measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Salivary 17-hydroxprogesterone 30 Saliva 413044009 | Saliva 17a-hydroxy progesterone 2.0 2.0 - Added by PITUS-14 Working group 2 measurement | Salmonella nucleic acid Salmonella species nucleic acid 23 838411000168108 | Salmonella species nucleic acid 3.0 3.0 - Added by PITUS-16 project assay | SARS-CoV nucleic acid Severe acute respiratory syndrome 21 399150003 | PCR test for SARS | 3.0 3.0 - Added by PITUS-16 project coronavirus PCR; SARS-CoV PCR; Coronavirus

Schistosomiasis Ab Schistosomiasis serology 18 Serum 171145000 | Schistosomiasis screening | 2.0 2.0 - Added by PITUS-14 Working group 2 Scl-70 Ab ENA; Topoisomerase-1 antibody 9 serum 35875005 | Antibody to Scl-70 measurement | 3.0 3.0 - Added by PITUS-16 project Selenium Se 8 Serum 166759002 | Serum selenium measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Selenium urine Urine Selenium; Urine Se 14 Urine 3683006 | Selenium measurement, urine | 2.1 2.1 - Changed preferred term from ‘Salivary 17- Hydroxprogesterone’ 2.0 - Added by PITUS-14 Working group 2 Selenium whole blood Whole Blood Selenium 20 Whole blood 38503009 | Selenium measurement, blood | 2.0 2.0 - Added by PITUS-14 Working group 2 Semen analysis - fertility Semen fertility test; Sperm count 26 Semen 11900001 | Semen analysis | 1.0 1.0 - Added by PUTS project Semen analysis post vasectomy Sperm Count Post Vasectomy 29 Semen 11743002 | Semen analysis, post vasectomy | 2.0 2.0 - Added by PITUS-14 Working group 2 Seminal fluid culture Seminal fluid MCS; Semen MCS 21 80731003 | Culture of semen | 3.0 3.0 - Added by PITUS-16 project Serotonin whole blood Whole blood 5-hydroxy tryptamine; Whole 21 Whole Blood 412837009 | Blood serotonin measurement | 3.0 3.0 - Added by PITUS-16 project blood 5-HT Sex hormone binding globulin SHBG 29 Serum 166585000 | Serum sex hormone binding globulin 1.0 1.0 - Added by PUTS project measurement | Shigella nucleic acid 21 838431000168103 | Shigella species nucleic acid assay 3.0 3.0 - Added by PITUS-16 project | Sialate 8 104932009 | Sialate measurement | 3.0 3.0 - Added by PITUS-16 project Sindbis virus nucleic acid Arbovirus nucleic acid 26 838451000168109 | Sindbis virus nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project

Sirolimus Rapamune; Rapamycin 9 Whole blood 412833008 | Blood sirolimus measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Skeletal muscle Ab Skeletal muscle antibodies; Anti-striated 18 Serum 391394003 | Serum anti-skeletal muscle antibody level 3.0 3.0 - Added by PITUS-16 project muscle antibodies; SMA | Skin Ab Skin antibodies 7 Serum 397600000 | Skin antibody measurement | 3.0 3.0 - Added by PITUS-16 project Skin basement membrane Ab Skin basement membrane antibodies; 25 serum 313805001 | Skin basement membrane antibody 3.0 3.0 - Added by PITUS-16 project Pemphigoid antibodies measurement | Skin prick testing Skin prick test; SPT; Skin prick allergen 18 37968009 | Prick test | 3.0 3.0 - Added by PITUS-16 project Sm Ab ENA; Smith extractable nuclear Ab 5 Serum 87459003 | Antibody to SM measurement | 3.0 3.0 - Added by PITUS-16 project Smooth muscle Ab 16 Serum 50744001 | Smooth muscle antibody measurement | 2.1 2.1 - Changed preferred term from ‘Smooth Muscle Ab’ 2.0 - Added by PITUS-14 Working group 2 Snake venom detection 21 Whole blood 444086002 | Detection of snake venom | 2.1 2.1 - Changed preferred term from ‘Snake Venom Detection’ 2.0 - Added by PITUS-14 Working group 2 Sodium Natrium; Na 6 Serum 104934005 | Sodium measurement, serum | 1.0 1.0 - Added by PUTS project Sodium urine Urine sodium; Urine Na 12 Urine 104935006 | Sodium measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Sodium urine 24h Sodium 24 hour urine; 24 hr urine Sodium 16 24 hr urine 313691004 | 24 hour urine sodium output 3.0 3.0 - Changed preferred term from 'Sodium 24 hr urine' measurement | 2.0 - Added by PITUS-14 Working group 2 Soluble transferrin receptor sTfR 28 408242005 | Soluble transferrin receptor test | 3.0 3.0 - Added by PITUS-16 project SSA Ab ENA; SSA/Ro60; Ro60; Sjogrens syndrome-A 6 Serum 59260005 | Antibody to SS-A measurement | 3.0 3.0 - Added by PITUS-16 project extractable nuclear Ab SSB Ab ENA; Sjogrens syndrome-B extractable 6 Serum 27904004 | Antibody to SS-B measurement | 3.0 3.0 - Added by PITUS-16 project nuclear Ab; SSB/La; La Streptococcal Ab Streptococal serology ASOT; Streptococal 16 Serum 117879007 | Measurement of streptococcal 2.0 2.0 - Added by PITUS-14 Working group 2 serology anti-DNAseB; ASOT deoxyribonuclease B antibody |

Streptococcus pneumoniae Ag Streptococcus pneumoniae antigen; 27 Serum 122120003 | Streptococcus pneumoniae antigen assay 3.0 3.0 - Added by PITUS-16 project Pneumococcal antigen; S. pneumoniae | antigen Streptococcus pneumoniae nucleic acid Streptococcus pneumoniae PCR; S. 37 841951000168107 | Streptococcus pneumoniae 3.0 3.0 - Added by PITUS-16 project pneumoniae PCR nucleic acid assay | Strongyloides Ab Strongyloides antibodies; Strongyloides sp 16 Serum 122122006 | Measurement of Strongyloides species 3.0 3.0 - Added by PITUS-16 project antibodies; Strongyloides stercoralis antibody | antibodies Succinylacetone 15 104946009 | Succinylacetone measurement | 3.0 3.0 - Added by PITUS-16 project Sulphaemoglobin 15 Whole blood 104950002 | Sulphaemoglobin measurement | 3.0 3.0 - Added by PITUS-16 project Sweat test 10 Sweat 168172001 | Sweat test | 2.0 2.0 - Added by PITUS-14 Working group 2 Synacthen short test Tetracosactrin short test; Tetracosactide 20 Multiple serum 252217003 | Short tetracosactrin test | 3.0 3.0 - Added by PITUS-16 project short test Synovial fluid examination 27 Synovial fluid 167859001 | Synovial fluid examination | 3.0 3.0 - Added by PITUS-16 project Syphilis serology Treponema serology; Antenatal screen 17 Serum; Blood; CSF 40675008 | Serologic test for syphilis | 3.0 3.0 - Added synonym 'Antenatal screen' 1.0 - Added by PUTS project T cell receptor gene rearrangement TCR gene rearrangement 35 69132002 | T cell receptor gene rearrangement | 2.0 2.0 - Added by PITUS-14 Working group 2 Tacrolimus level 16 Serum 313563000 | Serum tacrolimus measurement | 1.0 1.0 - Added by PUTS project Taenia solium Ab Tapeworm antibodies 16 Serum 122125008 | Measurement of Taenia solium antibody 3.0 3.0 - Added by PITUS-16 project | Testicular Ab Testicular antibodies 13 Serum 122163000 | Measurement of testis antibody | 3.0 3.0 - Added by PITUS-16 project Testosterone Testosterone total 12 Serum 270973006 | Serum testosterone measurement | 1.0 1.0 - Added by PUTS project Thallium Tl 8 Serum 105336005 | Thallium measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Thallium urine Urine Thallium; Urine Tl 14 Urine 76080003 | Thallium measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2 Thallium urine 24h Thallium 24 hour urine; 24 hr urine Thallium; 18 24 hr urine 444144005 | Quantitative measurement of thallium in 3.0 3.0 - Changed preferred term from 'Thallium 24 hr urine' 24 hr urine Tl 24 hour urine specimen | 2.0 - Added by PITUS-14 Working group 2 Thallium whole blood Whole Blood Thallium; Whole blood Tl 20 Whole blood 68940001 | Thallium measurement, blood | 2.0 2.0 - Added by PITUS-14 Working group 2 Theophylline Aminophylline; Nuelin 12 Serum 360360004 | Theophylline measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Thiocyanate 11 Serum 105337001 | Thiocyanate measurement | 3.0 3.0 - Added by PITUS-16 project Thiopurine methyltransferase 28 Plasma 121703007 | Thiopurine methyltransferase 3.0 3.0 - Added by PITUS-16 project measurement | Throat culture Throat swab; MCS throat; Throat microscopy, 14 Throat swab 117015009 | Throat culture | 3.0 3.0 - Added by PITUS-16 project culture and sensitivities Thrombin time 13 Plasma 55323000 | Thrombin time | 2.1 2.1 - Changed preferred term from 'Thrombin' 1.0 - Added by PUTS project Thyroglobulin 13 Serum 39966003 | Thyroglobulin measurement | 3.0 3.0 - Added by PITUS-16 project

Page 12 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History Thyroglobulin Ab Antithyroglobulin Ab; TG Ab 16 Serum 17164004 | Thyroglobulin antibody measurement | 3.0 3.0 - Added synonym 'TG Ab' 1.0 - Added by PUTS project Thyroid Ab Antithyroid Ab 10 Serum 104390007 | Anti-thyroid antibody measurement | 1.0 1.0 - Added by PUTS project

Thyroid function tests TFT; Thyroid function panel; Thyroid function 22 Serum 35650009 | Thyroid function test | 1.0 1.0 - Added by PUTS project profile Thyroid peroxidase Ab TPO; Thyroperoxidase Ab; Antithyroid 21 Serum 118002003 | Measurement of thyroperoxidase 3.0 3.0 - Added synonym 'TPO Ab' peroxidase Ab; TPO Ab antibody | 1.0 - Added by PUTS project Thyroid stimulating hormone TSH; Thyrotropin 27 Serum 313440008 | Serum TSH measurement | 1.0 1.0 - Added by PUTS project Thyroxine binding globulin TBG 26 Serum 38929004 | Thyroxine binding globulin measurement | 3.0 3.0 - Added by PITUS-16 project

TIBC Total iron binding capacity 4 Serum 359979000 | Total iron binding capacity measurement 2.0 2.0 - Added by PITUS-14 Working group 2 | Tin 3 Serum 29964007 | Tin measurement | 3.0 3.0 - Added by PITUS-16 project Titin Ab Skeletal muscle antibodies; Striated muscle 8 Serum 31753005 | Striated muscle antibody, measurement | 3.0 3.0 - Added by PITUS-16 project antibodies Tobramycin 10 Serum 389000 | Tobramycin measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Tobramycin level peak 21 Serum 442028003 | Measurement of tobramycin peak 3.0 3.0 - Added by PITUS-16 project concentration | Tobramycin level timed post dose 32 Serum 840861000168106 | Timed post dose tobramycin 3.0 3.0 - Added by PITUS-16 project measurement | Tobramycin level trough 23 Serum 441861006 | Measurement of tobramycin trough 3.0 3.0 - Added by PITUS-16 project concentration | Total bile acids Bile acids 16 Serum 5264008 | Total bile acids measurement | 3.0 3.0 - Added synonym 2.1 - Changed preferred term from ‘Total Bile Acids’ 2.0 - Added by PITUS-14 Working group 2 Total T3 8 Serum 89793009 | Tri-iodothyronine measurement, total | 3.0 3.0 - Changed SNOMED code from 313836009 to 89793009 2.0 - Added by PITUS-14 Working group 2 Toxocara Ab Toxocara antibodies 11 Serum 313641003 | Toxocara antibody measurement | 3.0 3.0 - Added by PITUS-16 project Toxoplasma Ab Toxoplasma serology; Toxo 13 Serum 408202000 | Toxoplasma serology | 2.0 2.0 - Added by PITUS-14 Working group 2 Toxoplasma gondii Ab Toxoplasma antibodies; T. gondii antibodies; 20 104308009 | Serologic test for Toxoplasma gondii | 3.0 3.0 - Added by PITUS-16 project Toxoplasmosis serology; Antenatal screen

Toxoplasma gondii nucleic acid Toxoplasma gondii PCR; T. gondii PCR 30 122304001 | Toxoplasma gondii DNA assay | 3.0 3.0 - Added by PITUS-16 project Toxoplasma nucleic acid Toxoplasma PCR 23 398454005 | Toxoplasma nucleic acid assay | 3.0 3.0 - Added by PITUS-16 project TPHA TPPA; Treponema pallidum particle 4 Serum; Blood; CSF 51571009 | Microhemagglutination test for antibody 1.0 1.0 - Added by PUTS project agglutination; Treponema pallidum to syphilis | haemagglutination Transferrin TRF 11 Serum 359982005 | Transferrin measurement | 1.0 1.0 - Added by PUTS project Transferrin saturation Transferrin sat 22 Serum 165730006 | Transferrin saturation | 2.0 2.0 - Added by PITUS-14 Working group 2 Transglutaminase Ab TTG Ab; TTG; Transglutaminase antibodies; 19 Serum 135853007 | Anti-tissue transglutaminase level | 3.0 3.0 - Changed preferred term from 'Tissue transglutaminase Ab'; Tissue transglutaminase antibodies Added synonyms 1.0 - Added by PUTS project Transglutaminase IgA Tissue transglutaminase IgA 20 Serum 412814003 | Tissue transglutaminase IgA 3.0 3.0 - Added by PITUS-16 project measurement | Transglutaminase IgG Tissue transglutaminase IgG 20 Serum 412815002 | Tissue transglutaminase IgG 3.0 3.0 - Added by PITUS-16 project measurement | Trichomonas vaginalis detection 31 122427005 | Trichomonas vaginalis detection | 3.0 3.0 - Added by PITUS-16 project Trichomonas vaginalis nucleic acid 34 122305000 | Trichomonas vaginalis rRNA assay | 3.0 3.0 - Added by PITUS-16 project Tricyclic antidepressants qualitative Antidepressants; Amitryptyline; Desipramine; 37 Serum; Plasma 250617002 | Detection of tricyclic antidepressant | 2.1 2.1 - Changed preferred term from ‘Tricyclic Antidepressants Imipramine; Nortriptyline; Pertofran; Qualitative’ Tofranil; Tryptanol 2.0 - Added by PITUS-14 Working group 2 Tricyclic antidepressants quantitative Antidepressants; Amitryptyline; Desipramine; 38 44787002 | Tricyclic antidepressant measurement | 3.0 3.0 - Added by PITUS-16 project Imipramine; Nortriptyline; Pertofran; Tofranil; Tryptanol Triglycerides TG; Trigs 13 Serum 166849007 | Serum fasting triglyceride measurement | 1.0 1.0 - Added by PUTS project

Troponin 9 Serum; Blood 105000003 | Troponin measurement | 1.0 1.0 - Added by PUTS project Troponin I 10 Serum; Blood 121870001 | Troponin I measurement | 1.0 1.0 - Added by PUTS project Troponin T 10 Serum; Blood 121871002 | Troponin T measurement | 1.0 1.0 - Added by PUTS project Trypanosome Ab Trypanosome antibody; Trypanosomal 14 Serum 122138000 | Measurement of Trypanosoma species 3.0 3.0 - Added by PITUS-16 project antibody antibody | Trypanosome identification Trypanosome detection 26 Whole blood 122139008 | Trypanosoma species identification | 3.0 3.0 - Added by PITUS-16 project Trypsin faeces 14 Faeces 64335008 | Faecal trypsin, quantitative | 3.0 3.0 - Added by PITUS-16 project Tryptase Mast cell tryptase 8 Serum 121873004 | Tryptase measurement | 3.0 3.0 - Added by PITUS-16 project TSH receptor Ab TSH receptor antibodies; TSH-R Ab; hTRAB; 15 Serum 54495009 | Antibody to TSH receptor measurement | 3.0 3.0 - Added by PITUS-16 project hTRAb; LATS; TSI Tuberculin sensitivity test Mantoux test; TST 27 424294008 | Delayed hypersensitivity skin test for 3.0 3.0 - Added by PITUS-16 project tuberculin PPD | Typhoid Ab Typhoid antibodies; Typhoid serology; Widal 10 Serum 165828002 | Widal test | 3.0 3.0 - Added by PITUS-16 project test Urate Uric acid; UA 5 Serum 273966000 | Serum urate measurement | 1.0 1.0 - Added by PUTS project Urate urine Urine Urate; Urine Uric Acid; Urine UA 11 Urine 271258007 | Urine urate measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Urate urine 24h Urate 24 hour urine; 24 hr urine Urate; Uric 15 24 hr urine 313663007 | 24 hour urine urate output measurement 3.0 3.0 - Changed preferred term from 'Urate 24 hr urine' Acid 24 hr urine; 24 hr urine UA | 2.0 - Added by PITUS-14 Working group 2 Urea 4 Serum 273967009 | Serum urea measurement | 1.0 1.0 - Added by PUTS project Urea urine Urine Urea 10 Urine 271259004 | Urine urea measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Urea urine 24h Urea 24 hour urine; 24 hr urine Urea 14 24 hr urine 313591008 | 24 hour urine urea output measurement 3.0 3.0 - Changed preferred term from 'Urea 24 hr urine' | 2.0 - Added by PITUS-14 Working group 2 Urinary pneumococcal Ag Urinary pneumococcal antigen; S. 23 Urine 408243000 | Urinary pneumococcal antigen test | 3.0 3.0 - Added by PITUS-16 project pneumoniae antigen; Streptococcus pneumoniae antigen; Pneumococcal antigen

Urine ALA 9 Urine 391398000 | Urine 5-aminolevulinic acid measurement 2.0 2.0 - Added by PITUS-14 Working group 2 | Urine dipstick 14 Urine 167226008 | Urine dipstick test | 2.1 2.1 - Changed preferred term from ‘Urine Dipstick' 2.0 - Added by PITUS-14 Working group 2 Urine microscopy casts Casts 22 Urine 167335004 | Urine microscopy for casts | 3.0 3.0 - Added by PITUS-16 project Urine microscopy eosinophil count 33 Urine 442562007 | Count of eosinophils in urine specimen | 3.0 3.0 - Added by PITUS-16 project

Urine microscopy red blood cells Urine microscopy red blood cells; Urine 32 Urine 310884001 | Urine microscopy: red cells | 3.0 3.0 - Added by PITUS-16 project microscopy dismorphic red cells; Urine microscopy RBC Uroporphyrinogen decarboxylase 30 105023000 | Uroporphyrinogen decarboxylase 3.0 3.0 - Added by PITUS-16 project measurement | Valproate level Valproic acid; Epilim 15 Serum 269868008 | Serum sodium valproate measurement | 1.0 1.0 - Added by PUTS project

Valproate level free 20 Serum 439758004 | Measurement of free valproic acid | 3.0 3.0 - Added by PITUS-16 project Vanadium 8 Serum 105354009 | Vanadium measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Vanadium urine 14 Urine 720191000168108 | Vanadium measurement, urine | 3.0 3.0 - Added by PITUS-16 project

Vanadium urine 24h 18 24 hr urine 719431000168104 | Vanadium measurement, 24 hour 3.0 3.0 - Added by PITUS-16 project urine | Vancomycin level 16 Serum 313712002 | Serum vancomycin measurement | 1.0 1.0 - Added by PUTS project Vancomycin level peak 21 Serum 441748004 | Measurement of vancomycin peak 1.0 1.0 - Added by PUTS project concentration | Vancomycin level random Vanco 23 Serum 439239007 | Measurement of vancomycin in random 1.0 1.0 - Added by PUTS project specimen | Vancomycin level trough 23 Serum 442169009 | Measurement of vancomycin trough 1.0 1.0 - Added by PUTS project concentration | Vanillyl mandelic acid urine 24h VMA 24hr urine 32 Urine 413005001 | 24 hour urine vanillylmandelic acid 1.0 3.0 - Changed preferred term from Vanillyl mandelic acid urine output measurement | 1.0 - Added by PUTS project

Variant haemoglobin 19 Whole blood 302763003 | Haemoglobin variant test | 2.1 2.1 - Changed preferred term from ‘Variant Haemoglobin’ 2.0 - Added by PITUS-14 Working group 2 Varicella zoster Ab VZ Ab; Herpes zoster serology; VZV Ab 19 Serum 104326007 | Measurement of Varicella-zoster virus 3.0 3.0 - Added synonym 'VZV Ab' antibody | 1.0 - Added by PUTS project Varicella zoster IgG 20 Serum 313587003 | Varicella-zoster virus antibody IgG 2.1 2.1 - Changed preferred term from ‘Varicella Zoster IgG’ measurement | 2.0 - Added by PITUS-14 Working group 2 Varicella zoster IgM 20 Serum 315231005 | Varicella-zoster virus antibody IgM 2.1 2.1 - Changed preferred term from ‘Varicella Zoster IgM’ measurement | 2.0 - Added by PITUS-14 Working group 2 Varicella zoster nucleic acid Herpes Zoster PCR; Varicella zoster PCR 29 398503008 | Varicella-zoster nucleic acid assay | 3.0 3.0 - Changed preferred term from 'Varicella zoster PCR' and added synonym 'Varicella zoster PCR' 2.1 - Changed preferred term from ‘Varicella Zoster PCR’ 2.0 - Added by PITUS-14 Working group 2 Vasoactive intestinal polypeptide VIP 33 Whole blood 59478003 | Vasoactive intestinal polypeptide 3.0 3.0 - Added by PITUS-16 project measurement | Vasopressin Level Anti-diuretic hormone; ADH; Arginine 17 Plasma 313833001 | Plasma arginine vasopressin 3.0 3.0 - Added by PITUS-16 project vasopressin measurement | VDRL Venereal disease research laboratory test 4 7786006 | VDRL test | 1.0 1.0 - Added by PUTS project

Very long chain fatty acids 27 Serum; Plasma 36305009 | Very long chain fatty acids measurement | 3.0 3.0 - Added by PITUS-16 project

VGCC Ab VGCC antibodies; Voltage gated calcium 7 Serum 391451007 | Serum voltage-gated calcium channel 3.0 3.0 - Added by PITUS-16 project channel Ab; Anti-voltage gated Ca channel antibody level | antibodies; Eaton Lambert syndrome antibodies; Lambert Eaton syndrome antibodies; LEMS antibodies

Page 13 of 14 Standards for Pathology Informatics in Australia (SPIA) Terminology for Requesting Pathology

RCPA Preferred term RCPA Synonyms Usage guidance Length Specimen Terminology binding (SNOMED CT-AU) Version History VGKC Ab VGKC antibodies; Voltage gated potassium 7 Serum; CSF 415828002 | Voltage gated potassium channel 3.0 3.0 - Added by PITUS-16 project channel Ab; Anti-voltage gated K channel antibody level | antibodies; CASPR2 antibodies; LGI1 antibodies; DPPX antibodies

Vibrio cholerae nucleic acid Vibrio cholerae PCR; Cholera 28 838461000168106 | Vibrio cholerae nucleic acid assay 3.0 3.0 - Added by PITUS-16 project | Viral culture Culture virus 13 12717000 | Viral culture | 1.0 1.0 - Added by PUTS project Viscosity plasma 16 Plasma 271214007 | Plasma viscosity measurement | 3.0 3.0 - Added by PITUS-16 project Viscosity whole blood 21 Whole blood 250408005 | Blood viscosity measurement | 3.0 3.0 - Added by PITUS-16 project Vitamin A Retinol 9 Plasma 76609004 | Vitamin A measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Vitamin B1 Thiamine 10 Whole blood 391392004 | Red cell vitamin B1 level | 2.0 2.0 - Added by PITUS-14 Working group 2 Vitamin B12 B12; Vit B12; Cyanocobolamin 11 Serum 271216009 | Serum vitamin B12 measurement | 1.0 1.0 - Added by PUTS project Vitamin B12 Red cell folate Vitamin B12 & Red cell folate; B12 and RCF; 27 Serum; Blood 395144002 | B12/folate level | 1.0 1.0 - Added by PUTS project B12 and Folate Vitamin B2 Riboflavin 10 Whole blood 391489002 | Red cell vitamin B2 level | 2.0 2.0 - Added by PITUS-14 Working group 2 Vitamin B6 Pyridoxal; Pyridoxine 10 Plasma 11829003 | Vitamin B6 measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Vitamin B6 whole blood Pyridoxal; Pyridoxine 22 Whole blood 391428007 | Red cell vitamin B6 level | 2.0 2.0 - Added by PITUS-14 Working group 2 Vitamin C Ascorbic acid 9 Plasma 27709003 | Ascorbic acid measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Vitamin D Vitamin D 25 hydroxy; Vitamin D 25 OH; 25 9 Serum 12199005 | Vitamin D, 25-hydroxy measurement | 3.0 3.0 - Added synonym 'Antenatal screen' hydroxycholecalciferol; 25 OH Vitamin D; 1.0 - Added by PUTS project Cholecalciferol; Vitamin D3; Antenatal screen

Vitamin D 1,25-dihydroxy 24 Serum 82457009 | Vitamin D, 1,25-dihydroxy measurement | 3.0 3.0 - Added by PITUS-16 project

Vitamin E Tocopherol 9 Plasma 7557006 | Vitamin E measurement | 2.0 2.0 - Added by PITUS-14 Working group 2 Vitamin K 9 105030006 | Vitamin K measurement | 3.0 3.0 - Added by PITUS-16 project von Willebrand factor Ag VWF:Ag 24 Plasma 408275002 | von Willebrand factor antigen level | 3.0 3.0 - Added by PITUS-16 project von Willebrand factor multimer 30 Plasma 63351009 | von Willebrand factor multimer assay | 3.0 3.0 - Added by PITUS-16 project

von Willebrand studies VWF; VW Factor; von Willebrand screening 22 Plasma 401129008 | von Willebrand screening test | 2.0 2.0 - Added by PITUS-14 Working group 2

VRE screening Vancomycin-resistant Enterococcus culture; 13 118007009 | Vancomycin resistant Enterococcus 3.0 3.0 - Changed preferred term from 'Vancomycin-resistant Infection control screening culture | Enterococci' and added synonyms 'Vancomycin-resistant Enterococcus culture; Infection control screening' 2.0 - Added by PITUS-14 Working group 2 Weak D testing 14 Whole blood 103879002 | Weak D blood group typing | 2.0 2.0 - Added by PITUS-14 Working group 2 West Nile Ab West Nile antibodies; Arbovirus antibody 12 420595000 | West Nile virus antibody measurement | 3.0 3.0 - Added by PITUS-16 project

West Nile nucleic acid Arbovirus nucleic acid 22 843621000168107 | West Nile virus nucleic acid assay 3.0 3.0 - Added by PITUS-16 project | White cell count White blood cell count; WCC; WBC; WBC 16 Whole blood 767002 | White blood cell count | 2.0 2.0 - Added synonym 'WBC Diff; Differential' Diff; Differential 1.0 - Added by PUTS project Yellow fever Ab Arbovirus antibody 15 122147008 | Measurement of Yellow fever virus 3.0 3.0 - Added by PITUS-16 project antibody | Yellow fever nuleic acid Arbovirus nucleic acid 24 122307008 | Yellow fever virus RNA assay | 3.0 3.0 - Added by PITUS-16 project Yersinia enterocolitica nucleic acid Yersinia enterocolitica PCR 36 843761000168105 | Yersinia enterocolitica nucleic 3.0 3.0 - Added by PITUS-16 project acid assay | Yersinia sp Ab Yersinia sp antibodies 14 Serum 104297007 | Measurement of Yersinia species 3.0 3.0 - Added by PITUS-16 project antibody | Yo Ab Neuronal antibodies; Paraneoplastic 5 Serum; CSF 394928002 | Yo antibody level | 3.0 3.0 - Added by PITUS-16 project neurologic antibodies; Cerebellar IIF; PCA-1; Antineuronal nuclear antibodies Zinc Zn 4 Serum 273975003 | Serum zinc measurement | 1.0 1.0 - Added by PUTS project Zinc 24 hr urine 16 24 hr urine 720041000168104 | Zinc measurement, 24 hour urine 3.0 3.0 - Added by PITUS-16 project | Zinc protoporphyrin ZPP; ZP; Free erythrocyte protoporphyrin; 19 104908002 | Zinc protoporphyrin measurement | 3.0 3.0 - Added by PITUS-16 project FEP Zinc urine Urine Zinc; Urine Zn 10 Urine 12652004 | Zinc measurement, urine | 2.0 2.0 - Added by PITUS-14 Working group 2

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