DOCSLIB.ORG

Meet the Stadtmans a Life Collected Neat, Sweet, Unique Joseph Edward Rall (1920–2008) by REBECCA BAKER (NIAID) and L.S

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Meet the Stadtmans a Life Collected Neat, Sweet, Unique Joseph Edward Rall (1920–2008) by REBECCA BAKER (NIAID) and L.S NATIONAL INSTITUTES OF HEALTH • OFFICE OF THE DIRECTOR | VOLUME 22 ISSUE 2 • MARCH-APRIL 2014 Meet the Stadtmans A Life Collected Neat, Sweet, Unique Joseph Edward Rall (1920–2008) BY REBECCA BAKER (NIAID) AND L.S. CARTER BY HANK GRASSO AND MICHELE LYONS, OFFICE OF NIH HISTORY luca Gat tinoni (NCI) took his “first steps into science” as a toddler in the NIH Child Care Center when his par- ents were Visiting Fellows at NIH. Physi- cist Kandice Tanner (NCI) is drawn to motion, whether it’s from tumor cells migrating into new tissues or her own body hurtling through space while she’s skydiving. Developmental biologist Todd HANKGRASSO, HISTORYNIH OFFICEOF Macfarlan (NICHD) is intrigued with how viruses “are so intimately intertwined with our own evolution as a species.” Indeed, all 11 members of the 2011– 2012 cycle of Earl Stadtman Tenure- Track Investigators have a story to tell. They join 17 others in the Stadtman program—named for the legendary biochemist who worked at NIH for 50 years—that was launched in 2009 as an This terra-cotta bas relief of Joseph Edward “Ed” Rall (background) and David Platt Rall (foreground) was created by NIH-wide recruiting effort to attract sculptor Christian Peterson. These brothers each left an impression on biomedical research and NIH. Ed Rall served NIH as deputy director for intramural research from 1983 to 1991. David Rall was the director of the National Institute of Envi- outstanding scientists whose research ronmental Health Sciences (1971–1990) as well as the founding director of the National Toxicology Program. areas span the biomedical fields. And to continue with the introduc- When Joseph “ed” Rall’s daughter, Priscilla Rall, decided to share her tions… RNA biology is “very exciting” father’s history with the NIH Stetten Museum and the National Library of Medi- to Stavroula (Voula) Mili (NCI), who cine (NLM), she welcomed representatives from both to her home and amazed studies cancer and neurodegeneration. them with her family’s extensive historical collections. Pia Rall had painstakingly Sunni Mumford (NICHD) is investi- collected, organized, and preserved the evidence of her father’s life and work—his gating how lifestyle and dietary changes legacy—and was interested in returning some of these resources to NIH so that may improve male and female reproduc- CONTINUED ON PAGE 10 tion and fertility. When she’s not trying to figure out the neuronal basis of natural CONTENTS behaviors, Yeka Aponte (NIDA) is pre- FEATURES • |1| Meet the Stadtmans |1| A Life Collected: Ed Rall |6| Interview with paring elaborate meals for her friends. Tanzanian Researcher Julie Makani |9| The Myriad Decision Eye researcher Kapil Bharti (NEI) had DEPARTMENTS • |2| DDIR: Nourishing the IRP |3| NIH Alumni News: André Van Steirteghem dreamed all his life about becoming a |4|Training Page: Mentoring |4|Abbreviations |5, 7| News You Can Use: 3D Print Exchange; CONTINUED ON PAGE 14 New HR Systems |8| Research Briefs |13| NIH in History: Centennial Anchor |16| Colleagues: Recently Tenured |19| Announcements |20| Photographic Moment: Window Washers FROM THE DEPUTY DIRECTOR FOR INTRAMURAL RESEARCH Nourishing Intramural Research for the Long Term BY MICHAEL GOTTESMAN, DDIR Bob Dylan noticed it in 1963, and 50 committees of our NIH experts and out- Please send your best ideas to your sci- years later we scientists are seeing it side experts formulating a 10-year scientific entific director and me for further consider- again: “The times they are a-changin’.” vision for each of the ICs and determining ation by the IC-based review groups. Once The conduct of science is evolving even what will be needed to accomplish these these individual groups have assembled their though resources are restricted; barriers goals. These ideas will be discussed by the recommendations, we will identify common to turning innovative ideas into reality SDs and by a committee of institute direc- themes and goals. Before the end of the keep springing up while being torn down tors, and the common themes that emerge year, we will ask the Advisory Committee elsewhere. We all know about the many will be identified and integrated into a single to the Director, comprising outside advisors, contributions that the intramural research document. to review our efforts. program (IRP) has made to modern bio- My hope is that this process—beginning Think big. Think not what you could do medical research (and I hope you all have within the NIH with outside encouragement with one more postdoc or a few more dollars. your elevator speech ready in case someone and support—will inspire creative, farsighted Instead think of unrealized synergies and challenges you on this), but how can we thinking. I know that for some IRP scien- focused investments for collaborative science best mold the future to assure its continued tists, planning of this sort generates angst. to take on major scientific questions. success? In the words of Lewis Thomas, I have detected that some of you don’t feel “The National Institutes of Health [IRP] included in the process. And yet this is an “Elevator Speech” Excerpt is not only the largest institution for bio- inclusive process that will flounder without medical science on earth, it is one of this broad input. So, inclusive planning was the VISITOR: What’s so great about the IRP? nation’s great treasures. As social inven- main topic for the 2014 IC Directors’ and IRP SCIENTIST: Remember Marshall Niren- tions for human betterment go, this one SDs’ retreats. Collins opened both discus- berg and the genetic code, Julius Axelod is a standing proof that, at least once in a sions and, in short, asked us to focus on the and humoral transmitters? Fluoride for tooth while, government possesses the capac- types of science that we do best. He charged decay; lithium for bipolar mental illness; ity to do something unique, imaginative, us to articulate visionary goals and identify blood tests to detect HIV and hepatitis; the useful, and altogether right.” barriers to achieving these goals. He stressed first AIDS drugs; the first vaccines against For the past nine months, I have been the enthusiastic Congressional interest in the hepatitis, Hemophilus influenza, and human meeting with NIH leadership to discuss value and benefits of our research. He spoke papillomavirus? That’s the IRP. We’ve had how to prepare ourselves for the future. In eagerly of exciting scientific opportunities 20-some Nobel Prize winners and 30-some January, I discussed a proposal for long-term that have emerged in the past few years. Lasker winners. planning for the IRP at the Leadership This 10-year vision is just the begin- VISITOR: But has the IRP done lately? Forum of Institute Directors. In February ning. We encourage all NIH scientists to IRP SCIENTIST: Ketamine to reduce suicidal the NIH scientific directors (SDs) met for contribute innovative ideas about how we tendencies; immunotherapy to cure cancer; their annual retreat—in the new FAES can continue to use the valuable resources discovery of genes involved in stuttering and conference center in the Clinical Center— of the IRP in laboratory science, clinical countless other disorders; world’s leader in sleeves rolled up and ready to work. With resources, and population-based programs to MRI technology; Undiagnosed Diseases the encouragement of NIH Director Fran- advance basic biomedical research and clini- Program; world’s largest hospital dedicated cis Collins, we have worked out a plan to cal applications. You are in a unique position to clinical studies… develop a blueprint for the future of the IRP. to provide a bold vision for the future of the Continue the ride at http://irp.nih.gov/ The planning process will begin at the NIH IRP, with your keen insights into the our-research/accomplishments. level of our institutes and centers (ICs) with special characteristics of this place. 2 THE NIH CATALYST MARCH-APRIL 2014 FROM THE DEPUTY DIRECTOR FOR INTRAMURAL RESEARCH NIH ALUMNI NEWS What’s Past Is Prologue Reflections on NIH Alumnus André Van Steirteghem BY ALAN N. SCHECHTER, NIDDK As my fiftieth anniversary as an minted protein chemist—having worked for NIH scientist nears in this period of stress a decade with Christian Anfinsen (who for NIH and its Intramural Research Pro- was a co-recipient of the Nobel Prize in gram (IRP), I am reminded of how fortu- Chemistry in 1972 for his work on protein nate I have been to be on the staff of this folding)—on top of my medical training. I institution. I am also optimistic that the found André space in my lab and we started past can continue to be prologue to the some classical, but inelegant, purification future. I realize that little of what we do is procedures. predictable and that, often, our contribu- When André returned to Brussels tions are from unanticipated developments. in 1977, the physicians in his university’s The recent visit ofAndré Van Steirteg- obstetrics and gynecology department were hem, one of the leaders in the field of in happy with his new expertise and hired him vitro fertilization (IVF) and now an emeritus to develop radioimmunoassays for use in professor of embryology and reproductive fertility studies. biology at Vrije Universiteit (the Free Uni- In July 1978, Robert Edwards and Pat- André Van Steirteghem, one of the leaders in the field of versity) in Brussels, was such an occasion. In rick Steptoe in England announced the first in vitro fertilization and an NIH alum, visited NIH recently. December 2013, he came to NIH to deliver successful use of IVF that culminated in the a lecture in which he recounted his work in birth of a healthy infant—Louise Brown.
Load more

Recommended publications
  • The Rosalind & Morris Goodman Cancer Research Centre
    The Rosalind & Morris Goodman Cancer Research Centre Annual Symposium May 6-7, 2021 McGill University Montreal (Qc) Canada Conference ! PROGRAM Table of Contents Sponsors 3 Policies 4 Welcome from the Organizing Committee 5 Program 6 Meet the Keynote Speakers 9 Abstracts 13 Research Staff Recognitions 16 The GCRC Annual Symposium, May 6-7, 2021 2 Sponsors This Symposium was made possible thanks to financial support from the Rosalind and Morris Goodman Cancer Research Centre and McGill University, Faculty of Medicine and Health Sciences sponsored by the Rose Wiselberg Foundation. The GCRC Annual Symposium, May 6-7, 2021 3 Policies Harassment Policy The Rosalind and Morris Goodman Cancer Research Centre (GCRC) is committed to maintaining a positive and respectful environment at its Symposia and other events. We expect participants in our events to engage in constructive and professional discussion, in which all are valued for their scien- tific contributions and work. We value diversity, and desire that no participant should be subjected to harassment while involved in our events. For purposes of this policy, harassment means unwelcome and offensive comments or be- haviour directed to the participant's sex, race, colour, national origin, religion, sexual orientation or gender identity, disability, or other status protected under applicable law. Harassment can include, for example, unwelcome attention, comments or jokes that focus on gender differences or sexual topics and that distract from the professional topics under discussion, unwelcome advances or re- quests for dates or sexual activities, and the use of language or images that demean or degrade per- sons of particular gender, racial, ethnic, religious or national identity.
    [Show full text]
  • Program Update: Year Three
    PHYSICAL SCIENCES-ONCOLOGY CENTER PROGRAM Program Update: Year Three Fall 2012 Table of Contents 1. Executive Summary .................................................................................................................................................................1 2. Physical Sciences-Oncology Program Organization ...............................................................................................................5 2.1. Introduction ..................................................................................................................................................................7 2.2. Office of Physical Sciences-Oncology Mission ............................................................................................................7 2.3. Program History ...........................................................................................................................................................8 2.3.1 Overview of Spring 2008 Think Tank Meetings ................................................................................................8 2.3.2 Program Development and Funding History ...................................................................................................10 2.4. Strategic Approach and Objectives ...........................................................................................................................11 2.4.1 A Focus on Addressing “Big Questions” in Oncology ....................................................................................11
    [Show full text]
  • Tissue Architectural Cues Drive the Emergence of Non-Random Trafficking of Human Tumor
    bioRxiv preprint doi: https://doi.org/10.1101/233361; this version posted December 13, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Tissue architectural cues drive the emergence of non-random trafficking of human tumor cells in the larval zebrafish. Colin D. Paula, Kevin Bishopb, Alexus Devinea, William J. Wulftangec, Elliott L. Painea, Jack. R. a d d a c Staunton , Steven Shema , Val Bliskovsky , Lisa M. Miller Jenkins , Nicole Y. Morgan , Raman Soodb, and Kandice Tannera* aLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health bZebrafish Core, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health cNational Institute of Biomedical Imaging and Bioengineering, National Institutes of Health d CCR Genomics Core, Center for Cancer Research, National Cancer Institute, National Institutes of Health * Corresponding author information: Dr. Kandice Tanner; Center for Cancer Research, National Cancer Institute, Building 37, Room 2132, Bethesda, MD 20892; Ph: 260-760-6882; Email: [email protected] Keywords: Cancer metastasis; organotropism; extravasation; organ intravital imaging; confined cell migration; topographical cues; tissue mechanics; tissue architecture bioRxiv preprint doi: https://doi.org/10.1101/233361; this version posted December 13, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license.
    [Show full text]
  • Transient External Force Induces Phenotypic Reversion of Malignant
    RESEARCH ARTICLE Transient external force induces phenotypic reversion of malignant epithelial structures via nitric oxide signaling Benjamin L Ricca1†, Gautham Venugopalan1†, Saori Furuta2, Kandice Tanner2,3‡, Walter A Orellana2,3, Clay D Reber1, Douglas G Brownfield1,2§, Mina J Bissell2*, Daniel A Fletcher1,2* 1Bioengineering Department and Biophysics Program, University of California, Berkeley, Berkeley, United States; 2Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, United States; 3Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, United States *For correspondence: [email protected] (MJB); [email protected] (DAF) Abstract Non-malignant breast epithelial cells cultured in three-dimensional laminin-rich extracellular matrix (lrECM) form well organized, growth-arrested acini, whereas malignant cells † These authors contributed form continuously growing disorganized structures. While the mechanical properties of the equally to this work microenvironment have been shown to contribute to formation of tissue-specific architecture, how Present address: ‡Laboratory of transient external force influences this behavior remains largely unexplored. Here, we show that Cell Biology, Center for Cancer brief transient compression applied to single malignant breast cells in lrECM stimulated them to Research, National Cancer form acinar-like structures, a phenomenon we term ‘mechanical reversion.’ This is analogous to Institute, Bethesda, United previously
    [Show full text]
  • Tissue Architectural Cues Drive Organ Targeting of Human Tumor Cells in Zebrafish
    bioRxiv preprint doi: https://doi.org/10.1101/233361; this version posted July 19, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. 1 Tissue architectural cues drive organ targeting of human tumor cells in zebrafish 2 3 Colin D. Paula, Kevin Bishopb, Alexus Devinea, Elliott L. Painea, Jack R. Stauntona, Sarah M. a a c b a* 4 Thomas , Lisa M. Miller Jenkins , Nicole Y. Morgan , Raman Sood , and Kandice Tanner 5 6 aLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National 7 Institutes of Health 8 bZebrafish Core, Translational and Functional Genomics Branch, National Human Genome 9 Research Institute, National Institutes of Health 10 cNational Institute of Biomedical Imaging and Bioengineering, National Institutes of Health 11 12 13 * Corresponding author and Lead Contact information: Dr. Kandice Tanner; Center for Cancer 14 Research, National Cancer Institute, Building 37, Room 2132, Bethesda, MD 20892; Ph: 260-760- 15 6882; Email: [email protected] 16 17 18 19 Keywords: Cancer metastasis; organotropism; extravasation; organ intravital imaging; confined 20 cell migration; topographical cues; tissue mechanics; tissue architecture 21 22 23 1 bioRxiv preprint doi: https://doi.org/10.1101/233361; this version posted July 19, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity.
    [Show full text]
  • 2017 National Veterinary Scholars Symposium 18Th Annual August 4
    2017 National Veterinary Scholars Symposium 18th Annual August – 4 5, 2017 Natcher Conference Center, Building 45 National Institutes of Health Bethesda, Maryland Center for Cancer Research National Cancer Institute with The Association of American Veterinary Medical Colleges https://www.cancer.gov/ Table of Contents 2017 National Veterinary Scholars Symposium Program Booklet Welcome .............................................................................................................................. 1 NIH Bethesda Campus Visitor Information and Maps .........................................................2 History of the National Institutes of Health ......................................................................... 4 Sponsors ............................................................................................................................... 5 Symposium Agenda .......................................................................................................6 Bios of Speakers ................................................................................................................. 12 Bios of Award Presenters and Recipients ........................................................................... 27 Training Opportunities at the NIH ...................................................................................... 34 Abstracts Listed Alphabetically .......................................................................................... 41 Symposium Participants by College of Veterinary Medicine
    [Show full text]
  • Characterization and Tissue Localization of Zebrafish Homologs of the Human ABCB1 Multidrug Transporter
    bioRxiv preprint doi: https://doi.org/10.1101/2021.02.18.431829; this version posted February 18, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. This article is a US Government work. It is not subject to copyright under 17 USC 105 and is also made available for use under a CC0 license. Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter Robert W. Robey,1 Andrea N. Robinson,1 Fatima Ali-Rahmani,1 Lyn M. Huff,1 Sabrina Lusvarghi,1 Shahrooz Vahedi,1 Jordan Hotz, 1 Andrew C. Warner,2 Donna Butcher,2 Jennifer Matta,2 Elijah F. Edmondson, 2 Tobie D. Lee,3 Jacob S. Roth,3 Olivia W. Lee,3 Min Shen, 3 Kandice Tanner,1 Matthew D. Hall, 3 Suresh V. Ambudkar,1 Michael M. Gottesman1* 1Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 2Molecular HistoPathology Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD 3National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD Short title: Characterization and localization of zebrafish ABCB1 homologs *CorresPonding author: [email protected] 1 bioRxiv preprint doi: https://doi.org/10.1101/2021.02.18.431829; this version posted February 18, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. This article is a US Government work. It is not subject to copyright under 17 USC 105 and is also made available for use under a CC0 license.
    [Show full text]
  • 17Th Annual Nih Graduate Student Research Symposium Faces of Tomorrow's Science
    17th ANNUAL FEBRUARY 21, 2021 NIH GRADUATE STUDENT RESEARCH SYMPOSIUM: FACES OF TOMORROWS SCIENCE 17TH ANNUAL NIH GRADUATE STUDENT RESEARCH SYMPOSIUM FACES OF TOMORROW'S SCIENCE 2021 FOREWORD AND ACKNOWLEDGEMENTS ......................... 2 PROGRAM OF EVENTS ........................................................ 4 NIH GRADUATE PARTNERSHIPS PROGRAM GRADUATION AWARD RECIPIENTS ................................... 6 OUTSTANDING MENTOR AWARDS ....................................10 STUDENT SPEAKERS .........................................................12 STUDENTS ...........................................................................16 POSTERS ............................................................................ 20 Graduate Partnerships Program Office of Intramural Training & Education Office of Intramural Research National Institutes of Health U.S. Department of Health & Human Services 1 NATIONAL INSTITUTES OF HEALTH FOREWORD Every year, the National Institutes of Health (NIH) Graduate Student Research Symposium showcases the breadth of scientific research and the achievements of the graduate student community at the NIH. The symposium is the largest graduate student event of the year - an event in which graduate students can come together to share their research, appreciate the work of their colleagues, and celebrate the successes of the graduate student community. In its seventeenth year, this annual symposium provides an opportunity to acknowledge the scientific accomplishments of the hundreds of graduate students working
    [Show full text]
  • Cell-Specific Cargo Delivery Using Synthetic Bacterial Spores
    bioRxiv preprint doi: https://doi.org/10.1101/2020.02.13.947606; this version posted February 13, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. This article is a US Government work. It is not subject to copyright under 17 USC 105 and is also made available for use under a CC0 license. Cell-specific cargo delivery using synthetic bacterial spores Minsuk Kong1, Taylor B. Updegrove1, Maira Alves Constantino2, Devorah L. Gallardo3, I-Lin Wu1, David J. Fitzgerald1,*, Kandice Tanner2,*, and Kumaran S. Ramamurthi1,* 1Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA 2Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA 3Laboratory Animal Sciences Program, Leidos Biomedical Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA *To whom correspondence should be addressed. Email: [email protected] (D.J.F.) [email protected] (K.T.), or [email protected]; (K.S.R.) Keywords: SpoVM; SpoIVA; DivIVA; sporulation; Bacillus subtilis, nanoparticle bioRxiv preprint doi: https://doi.org/10.1101/2020.02.13.947606; this version posted February 13, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. This article is a US Government work. It is not subject to copyright under 17 USC 105 and is also made available for use under a CC0 license. ABSTRACT SSHELs are synthetic bacterial spore-like particles wherein the spore’s cell surface is partially reconstituted around 1 µm-diameter silica beads coated with a lipid bilayer.
    [Show full text]
  • Updated Abstract Book CCR FYI Colloquium 2021 Final 4.19.21.Pdf
    The Center for Cancer Research Fellows and Young Investigators Steering Committee presents: 21st Annual From Mechanisms to Therapies: CCR-FYI Current Highlights in COLLOQUIUM Cancer Research Analysis Testing Treatment April 19–20, 2021 Program U.S. Department of Health & Human Services | National Institutes of Health 21st Annual Center for Cancer Research Fellows and Young Investigators (CCR-FYI) Colloquium 21st Annual Center for Cancer Research Fellows and Young Investigators (CCR- FYI) Colloquium SCHEDULE AND PROGRAM BOOK From Mechanisms to Therapies: Current Highlights in Cancer Research April 19th- 20th, 2021 For internal use only 21st Annual CCR Fellows and Young Investigators Colloquium 21st Annual Center for Cancer Research Fellows and Young Investigators (CCR-FYI) Colloquium Welcome Letter Welcome Colloquium Participants! On behalf of the NCI Center for Cancer Research Fellows and Young Investigators (CCR-FYI) Steering Committee and CCR-FYI Colloquium Subcommittee, we welcome you to the 21st Annual CCR-FYI Colloquium. The CCR-FYI strives to promote scientific, career, and personal success and growth among all postdoctoral fellows, clinical fellows, postbaccalaureate fellows, and graduate students on the NIH campuses. We are kindly assisted by the NCI’s Center for Cancer Research (CCR) Office of the Director and the Center for Cancer Training (CCT) Office of Training and Education, who work to enhance the intramural trainee experience. The CCR-FYI would like to thank Dr. Ned Sharpless, Dr. Glenn Merlino, Dr. William Dahut, Dr. Tom Misteli, Erika Ginsburg, Dr. Oliver Bogler for their continuing assistance and guidance. We would also like to thank Angela Jones from the Center for Cancer Training, Robert Montano and his team from the Center for Biomedical Informatics and Information Technology for providing us with the managerial and technical help, respectively.
    [Show full text]
  • MEET the FACULTY CANDIDATES Candidates Will Be Present to Meet with Faculty Recruiters on Wednesday, October 16, 2019 from 3:30P
    MEET THE FACULTY CANDIDATES Candidates will be present to meet with faculty recruiters on Wednesday, October 16, 2019 from 3:30pm – 5:30pm in Exhibit Hall DE. Admission to the Poster Forum (other than candidates below) are by a business card showing that the individual is a faculty recruiter and a valid BMES Annual Meeting badge. AMR ASHRAF ABDEEN, PhD Wisconsin Institute for Discovery, University of Wisconsin, Madison, WI . [email protected] Research Overview: My interests lie at a unique intersection of biomaterials and mechanobiology, genomics and stem cell therapies. I aim to advance the analysis of biomaterial-cell interaction, fundamental mechanobiology and biomaterials-based therapeutics using novel genome engineering methods in the biomaterials field. My doctoral work focused on the use of biomaterials to probe cell-matrix interaction – how cell matrix affects their differentiation and secretory profile for therapeutic purposes. My postdoctoral work focuses on the more translational usage of biomaterials for therapies. Here, I’ve worked on protein delivery for genome editing, had exposure to state -of the-art regenerative stem cell therapies (for in vivo implantation) and immunotherapies (such as CAR-T therapies). In addition, I now have extensive experience in CRISPR-based genome manipulation for fundamental studies as well as therapeutic purposes. This work involved learning more sophisticated, high-throughput molecular biology assays. One focus of my lab will be studying the more fundamental biomaterials-cell interactions using unbiased biological methods such as high throughput sequencing or functional screens, coupled with a library of biomaterials that covers a wide range of materials properties. Another focus will be the m ore translational aspect of therapeutics, with a focus on delivery techniques for both gene and cell therapies.
    [Show full text]
  • Science Highlightsletter of the 2019 This Is Your Last Issue of the 8 26 ASCB|EMBO Meeting Newsletter If You Haven’T Renewed Your ASCB Membership
    ascb february 2020 | vol. 43 | no. 1 NEWSteam science highlightsLETTER of the 2019 this is your last issue of the 8 26 ASCB|EMBO meeting Newsletter if you haven’t renewed your ASCB membership science Transition to a Biotech Career Discover the business side of science, network, and learn interdisciplinary skills through a team project. Of the 182 attendees in 2014-2017, 67% now have jobs in industry, regulatory affairs, or tech transfer. Scholarships ranging from $200-$400 are available. Biotech East: May 31–June 6, at Manning School of Business, University of Massachusetts Lowell 2019Biotech West: July 12–17, at Keck Graduate Institute, Claremont, CA biotechApplication deadline for both course courses is March 31 Supported by More Info/Apply at ascb.org/career-development/biotech-course @ascbiology newbiotechflyer2020.indd 1 2/7/2020 11:11:07 AM contents february 2020 | vol. 43 | no. 1 introduction member news president’s column prophase 3 4 5 24 47 Transition to a features 8 “not just a cog”: a q&a on team science 11 team science: experiences from the trenches Biotech Career in cell biology and why being canadian doesn’t hurt regular issue content Discover the business side of science, network, and learn interdisciplinary skills through a team ascb news changes to bylaws on the ballot for spring . 14 minorities affairs committee (mac) project. Of the 182 attendees in 2014-2017, 67% matt welch takes helm of mboc .. 16 poster competition winners . 38 now have jobs in industry, regulatory affairs, or the günter blobel early career award . 16 corporate and foundation partners .
    [Show full text]