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DIA 2012 Collaborate to Innovate FINAL PROGRAM 48th Annual Meeting June 24-28 | Philadelphia, PA Pennsylvania Convention Center www.diahome.org/DIA2012 Craig H. Lipset Head of Clinical Innovation, Worldwide Research & Development, Michael A. Nutter Pfizer Inc Mayor of Philadelphia Dear Colleagues, Welcome to Philadelphia and to DIA’s 48th Annual Meeting. Thank you for attending the DIA 2012 48th Annual Meeting. I am thrilled that the DIA 2012 48th Annual The theme of this year’s Annual Meeting is Collaborate to Innovate. What Meeting Collaborate to Innovate is being does this mean? It means that over the next few days you will attend and held right here in the Birthplace of American participate in tutorials, sessions, workshops, symposia, and panel discus- Medicine. Philadelphia is the perfect setting sions to address the collaboration required among diverse partners to for your gathering. It is home to some of the bring innovative new medical products to patients. world’s most renowned institutions of higher learning, where the best and the brightest To me, that is what the DIA Annual Meeting is all about—putting new minds are leading the quest for new medical ideas into practice, producing rich content, offering robust networking discoveries and innovations. opportunities, and providing access to the world’s most innovative tech- nology partners—so we can continue to make an important impact in the Philadelphia is fortunate to have DIA’s delivery of new therapies to patients. global headquarters located just a few miles outside Center City—making it a part of the "Innovation" is a very popular buzzword, but it’s more than just good fabric of our great city. And we share your ideas; it’s putting those ideas into practice and ultimately realizing value. vision of improving health and well-being worldwide. Thank you for attending the DIA 2012 Annual Meeting. I look forward to collaborating with each of you this week. While you are here in Philadelphia, please take the opportunity to visit our cultural Sincerely, attractions and historic American landmarks and enjoy the warm hospitality of our outstanding restaurants and the independent spirit of our unique retail corridors. I want to thank you for attending this year’s Craig H. Lipset DIA Annual Meeting and wish each of you a Program Chair very successful four days here in the City of Brotherly Love. Sincerely, Michael A. Nutter Mayor of Philadelphia TABLE OF CONTENTS 4 7 10 22 145 Keynote Speaker Featured Offerings Networking Meeting Agenda Exhibiting Companies THE MOST PRODUCTIVE FOUR DAYS Schedule At-A-Glance ................................................................2 YOU’LL HAVE ALL YEAR DIA 2012 Annual Meeting Tracks ............................................3 Opening Plenary Session ..........................................................4 Ultimately, convergence is about mutual respect, Featured Offerings in This Year’s Program ..........................5 working together, and being open to new ideas Building Relationships Worldwide ........................................ 6 and learning from each other. To that end, DIA Special Features ...........................................................................8 2012 provides the best opportunity to meet with New Experiences ........................................................................ 9 people from around the world, share your views and Networking Opportunities ......................................................10 knowledge, network, and build new relationships. Program Committee .................................................................12 DIA Board of Directors ............................................................. 13 Getting Around Philadelphia ..................................................17 General Information ..................................................................18 Continuing Education ..............................................................20 Meeting Schedule .....................................................................22 Monday, June 25 ...............................................................33 Tuesday, June 26 .............................................................. 57 Wednesday, June 27 .........................................................81 Thursday, June 28 ...........................................................109 DIA ANNUAL MEETING MOBILE APP Preconference Program & Tutorials.....................................117 The DIA Annual Meeting Poster Program .........................................................................118 app is FREE and available Award Winners ..........................................................................121 on Android™, iPhone®, iPad®, as well as Mobile Web. Speaker Index ...........................................................................123 Download the mobile app to Speaker Disclosure Statements ...........................................133 access a wide range of DIA 2012 information as well as Universal Activity Numbers ...................................................141 the ability to: List of Exhibitors ......................................................................145 Manage your agenda đƫ Exhibitor Directory ................................................................. 150 đƫ Receive news and announcements Preconference Programs & Tutorials ...................................191 đƫ Network with fellow Hotel Information.....................................................................201 attendees đƫ Receive event Attendee Registration Form ................................................203 information in real time Preconference Programs & Tutorials Visit the DIA booth in the Exhibit Hall for instructions or Registration Form ..........................................................204 www.diahome.org/DIA2012mobile Exhibit Personnel Registration Form ................................205 1 TUESDAY, JUNE 26 Registration Hours: DIA 2012 7:00 AM–4:30 PM Attendee, Speaker, and Exhibitor Registration Schedule: Collaborate to Innovate 7:15–8:00 AM Coffee and Breakfast Breads SCHEDULE AT-A-GLANCE 8:00–9:30 AM Concurrent Educational Opportunities 9:00 AM–3:30 PM Exhibition Hall Open SATURDAY, JUNE 23 9:30–10:00 AM Coffee Break 10:00–11:30 AM Concurrent Educational Opportunities Registration Hours: 11:00 AM–1:30 PM Professional Poster Session #1 9:00 AM–5:00 PM Exhibitor Registration 11:30 AM–1:00 PM All SIAC Luncheon Group 11:30 AM–1:30 PM Lunch with Optional Interest Area Seating 12:00–12:45 PM Innovation Theater Presentation: ADDPLAN PE- SUNDAY, JUNE 24 Innovative Software for Population Enrichment Designs in Adaptive Clinical Trials Registration Hours: 1:30–3:00 PM Concurrent Educational Opportunities 8:00–9:00 AM Registration for Full-day, Morning Preconference Program/Tutorials 1:30–3:30 PM Exhibit Guest Passes 8:00 AM–6:00 PM Exhibitor Registration 3:00–3:30 PM Refreshment Break 12:30–1:00 PM Registration for Afternoon Preconference Program/ 3:30–4:30 PM Concurrent Educational Opportunities Tutorials 4:30–6:30 PM Adaptive Design Scientific Working Group 3:00–6:00 PM Attendee and Speaker Registration Schedule: 8:30 AM–12:00 PM Half-day Morning Preconference Tutorials WEDNESDAY, JUNE 27 9:00 AM–5:00 PM Full-day Preconference Tutorials 1:00–4:30 PM Half-day Afternoon Preconference Tutorials Registration Hours: 3:00–5:00 PM Student Forum 7:00 AM–5:00 PM Attendee, Speaker, and Exhibitor Registration Schedule: 7:15–8:00 AM Coffee and Breakfast Breads MONDAY, JUNE 25 8:00–9:30 AM Concurrent Educational Opportunities 9:00–3:30 PM Exhibition Hall Open Registration Hours: 9:30–10:00 AM Coffee Break 7:00 AM–6:30 PM Attendee, Speaker, and Exhibitor Registration 10:00–11:30 AM Concurrent Educational Opportunities Schedule: 11:00 AM–1:30 PM Professional Poster Session #2 7:15–8:00 AM Coffee and Breakfast Breads 11:30 AM–1:30 PM Lunch with Optional Interest Area Seating 7:15–8:00 AM Orientation/Networking and Coffee for DIA 2012 Annual Meeting First-timers 1:30–3:00 PM Concurrent Educational Opportunities 8:00–9:30 AM Opening Plenary Session 1:30–3:30 PM Exhibit Guest Passes 9:30–10:00 AM Coffee Break 3:00–3:30 PM Refreshment Break 9:30–10:00 AM Orientation and Coffee for DIA 2012 Annual Meeting 3:30–5:00 PM Concurrent Educational Opportunities First-timers 5:15–7:00 PM Consortium of Academic Programs in Clinical Research 10:00–11:30 AM Concurrent Educational Opportunities 11:00 AM–6:30 PM Exhibition Hall Open 11:00 AM–6:30 PM Student Poster Session THURSDAY, JUNE 28 11:30 AM–1:30 PM Lunch with Optional Interest Area Seating Registration Hours: 12:00–12:45 PM Innovation Theater Presentation: Innovation in R&D and – AM Commercialization through Big Data Analytics 8:00 11:00 Attendee and Speaker Registration 1:30–3:00 PM Concurrent Educational Opportunities Schedule: 8:15–9:00 AM Coffee and Breakfast Breads 3:00–3:30 PM Refreshment Break 9:00–10:30 AM Concurrent Educational Opportunities 3:30–5:00 PM Concurrent Educational Opportunities 10:30–10:45 AM Coffee Break 5:00–6:30 PM Welcome Reception 10:45–12:15 PM Concurrent Educational Opportunities 6:00 PM Student Poster Award Ceremony 12:30–5:00 PM MedDRA® User Group Meeting 2 DIA 2012 ANNUAL MEETING TRACKS The DIA 2012 Annual Meeting is the largest multidisciplinary event for professionals involved in the discovery, development and life cycle management of pharmaceuticals, biotechnology, medical devices and related health care products. This year’s program is comprised of 22 Tracks which are related to specific interest
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