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CENTRE FOR IMMUNE REGULATION (CIR) 56 FINAL REPORT 2007–2017 57 Rajesh Grover, The Scripps Oliver Pabst, Hannover Medical Guest lecturer Research Institute, California, US School, Germany A Battle for Survival: Dynamics of the IgA response SEMINAR Chronic Bacterial Infections – Unexpected Consequences Roberta Pelanda, 1DWLRQDO-HZLVK “Transition from program Health and University of Colorado and B Cell Lymphoma and academia to industry” Myeloma – Bacterial Origins? Denver School of Medicine, US The guest lecturer program has been organised by a post- Click your heels: you are The postdoc committee Marc K. Jenkins, University in the land of B cells has also arranged a semi- doc committee with representatives from all the research of Minnesota, US nar with national speakers - The CD4+ T cell response Shimon Sakaguchi, Osaka JURXSVDW&,57KHFRPPLWWHHKDVLQYLWHGKLJKUDQNHGLQWHU who have either performed to bacterial infection 8QLYHUVLW\-DSDQ national researchers to come to Oslo to stay with our centre Molecular basis of regulatory a successful transfer from one or two days to interact with researchers at the centre and Steffen Jung, Weizmann T cell development and their academia to industry or are Institute of Science, Israel JLYHDSXEOLFJXHVWOHFWXUH7KHUHVXOWLVDORQJYLVLWRUOLVWRI functional stability involved in the transition thirty researchers from excellent research institutions all over Macrophages – development process. & tissue specialisation Bernd Schröder, Christian-Albrechts- WKHZRUOG7KHLUNQRZOHGJHDQGH[SHUWLVHKDVFRQWULEXWHG University of Kiel, Germany Øystein Rekdal, CSO, strongly to shape the research at CIR, and several collabora- Ludger Klein, Ludwig Maximilians SPPL intramembrane proteases Universität München, Germany – How they control immune cell Lytix Biopharma, Oslo tive projects and researcher exchange have been initiated as Shaping of the CD4 T cell development and function From bench to bedside DUHVXOWRIWKHVHYLVLWV repertoire by a self-antigen of the central nervous system Michael Sieweke, Centre d'Immuno- oncolytic peptide logie de Marseille-Luminy, France Thomas Seth Kupper, Harvard Beyond stem cells : Marophage Geir Åge Løset, CSO, Medical School, US self renewal and identity Nextera, Oslo T cell memory: new insights Basic research and Caetano Reis e Sousa, industrial translation Committee members 2007–2017 Ralf Küppers, University of The Francis Crick Institute, UK – the ultimate blend Duisburg-Essen, Germany A DaNGeRous talk Agnete Fredriksen, CSO, -DQ7HUMH$QGHUVHQ • Espen Bækkevold • Sudhir Kuman Chauhan • Elena Danilova • Roberto DiNiro • Even Generation and function of about dendritic cells Vaccibody, Oslo Fossum • Dominik Michael Frei • Ramakrishna Gopalakrishnan •7RQH)*UHJHUV •/LVD0*UXEHU •.ULVWLQ6 human memory B cells and Sarah Teichmann, EMBL From PhD to CSO in Clinical Gunnarsen • Peter Huszthy • • • • Nadia Mensali aspects of CLL pathogenesis -RKDQQH7-DFREVHQ 2OH-%/DQGVYHUN 0DULD+/H[EHUJ European Bioinformatics Institute stage Biotech Company – my • Cinzia Progida • Shuo-Wang Qiao • Charlotta Sandin • Omri Snir • Peter Szodoray •,QJHU\QHEUnWHQ Ana-Maria Lennon-Duménil, & WT Sanger Institute, UK Institut Curie, France Understanding cellular Coordinating cell migration heterogeneity André Borka, Head hunter, Borka Consulting, Oslo with function: the example Guest lectures of dendritic cells Gabriel D. Victora, Whitehead (Work)Life after PhD within Institute for Biomedical Research, US the pharmaceutical industry, Arne Akbar, University Matthew Collin, Newcastle Michael Dustin, Oxford Vivianne Malmström, Karolinska Darwin in miniature: antibody medical technical equipment College London, UK University, UK University, Kennedy Institute University hospital, Sweden evolution in germinal centers and life science. Advice Defective T Cell Immuno- Human dendritic cells of Rheumatology, UK Dissecting autoimmunity Hedda Wardemann, Deutsches surveillance During Ageing in health and disease T cell signal integration and - T and B cell responses in applications Krebsforschungszentrum, Germany decision making based on Rheumatoid Arthritis Mats Bemark, University Simon J. Draper, University synapses and kinapses The B cell antibody repertoire Ana Kucera, Regional Sales of Gothenburg, Sweden of Oxford, UK Eric Meffre, Yale University, US in health and disease Manager Carl Zeiss AS, Oslo Beyond the bone marrow Development of broadly- Zoltan Fehervari, Nature The establishment of B cell From PhD to industry: Patrick C. Wilson, University neutralising vaccines against Publishing Group, US tolerance: of humanized mice the pros and cons and of Chicago, US differentiation the blood-stage infection How to get published: and men and Self-reactive the process behind of human malaria the agony and the ecstasy Human antibody responses Andrea Cerutti, Mount Sinai and gut homeostasis defects School of Medicine, US Deborah Dunn-Walters, Frederic Geissmann, King's Gur Yaari, Bar-Ilan University, Israel Class switching at the King's College London, UK College London, UK Lill Mårtensson-Bopp, University Mining B cell repertoire mucosal interface Spectratype and High Differentiation and functions of Gothenburg, Sweden dynamics from next-generation Throughput Sequencing Autoreactive B cells; a road sequencing studies analysis of B cell repertoire to autoimmune disease? CENTRE FOR IMMUNE REGULATION (CIR) 58 FINAL REPORT 2007–2017 59 Hyun-Dong Chang, Deutsches Thorbald van Hall, Leiden Univer- Tissue control of effector Rheuma-Forschungszentrum Berlin, sity Medical Center, the Netherlands responses Guest lectures a Leibniz Institute, Germany Tumors with processing defects From human to mouse: Reverse - display novel tumor antigens engineering of a mouse model tory Th lymphocytes to chronic by visiting professors via the non-classical HLA-E for CD and other guests Kristian Hannestad, Oslo Kjetill S. Jacobsen, University Yueh-hsiu Chien, Stanford University Hospital of Oslo University, US CIR has arranged an extensive number of seminars, sympo- Anti-nucleosomal antibodies in Genome sequence of Atlantic Gamma Delta T cells: First siums and lectures with external international and national a mouse model for SLE cod reveals a unique immune line of Defense and Beyond Adrian Hayday, King’s College system through the loss of MHC VSHDNHUVRSHQIRUWKHZKROHVFLHQWLÀFHQYLURQPHQWLQ2VOR II function Some of the events have been arranged in collaboration with Peter Cresswell, Yale School London, UK of Medicine, US other research centres in Oslo and the Norwegian Society of The dominant role of body sur- Jørgen Jahnsen, Aker University face epithelia in shaping local T Hospital metabolic regulator co-opted by ,PPXQRORJ\([WHUQDOVSHDNHUVKDYHDOVREHHQLQYLWHGWRRXU cell immunity Treatment goals for IBD human cytomegalovirus VHYHQ&,5UHWUHDWV,QWRWDOLQFOXGLQJWKHJXHVWVLQYLWHGE\WKH Dag O. Hessen, University of Oslo postdoc committee, more than 100 different speakers have Sirpa Jalkanen, University of Turku, Mark M. Davis, Stanford University, The Red Queen principle in Finland - CA, US FRQWULEXWHGWRDFWLYLWLHVLQLWLDWHGE\WKHFHQWUH&HQWUHPHP nature and culture ฀ Systems immunology and its bers have also contributed with a multitude of lectures at the as targets to prevent cancer application to human beings Mark Hogarth, Burnet Institute, growth and spread VHPLQDUVDQGV\PSRVLXPV Australia ฀฀ recognition and applications to Antibody and Fc-receptor Leo James, MRC Laboratory of human responses interactions in humans and Molecular Biology, UK other primates. Implications for Intracellular Antibody Immu- Immunology Taught by the development of vaccines, nity and the Cytosolic Fc Recep- Humans therapeutic antibodies and the tor TRIM21 Sigbjørn Fossum, University Intracellular Immunity: target- External speakers and lectures 2007–2017 of Oslo Trygve Holmøy, Oslo University ing and neutralizing viruses The role of APLEC receptors Hospital inside infected cells in adjuvant induced arthritis The immunology of multiple sclerosis Marc Jenkins, University of William Agace, University of Lund, Richard Blumberg, Harvard Maria Bottermann, MRC Johan Garssen, University of Minnesota, US Sweden Medical School, US Laboratory of Molecular Biology, UK Utrecht and Danone Research Patrick Holt, Telethon Institute The CD4+ T cell response to Intestinal Dendritic cells, reti- Endoplasmic Reticulum Stress Adenoviral gene delivery is Centre for Specialised Nutrition, for Child Health Research in bacterial infection The Netherlands noic acid, and their role in the inhibited by sequential comple- Perth, Australia regulation of intestinal T cell ment-mediated virion inactiva- Immunomodulation by dietary Interactions between innate Imre Kacskovics, Eötvös Loránd Regulation of Lymphocyte responses tion and TRIM21 neutralization intervention: the cutting edge and adaptive immunity in University, Hungary Function by Carcinoembryonic between food and pharma asthma pathogenesis: new per- Accelerating antibody discov- Antigen Adhesion Molecule 1: Maria Therese Ahlen, The Arctic Søren Buus, University of spectives from studies on acute ery using transgenic animals Marcos González-Gaitán, University of Norway Copenhagen, Denmark exacerbations overexpressing the neonatal Fc and Cancer University of Geneva, Switzerland Fighting FNAIT – murine receptor as a result of aug- Treg-mediated control of models and antibody prophy- The immunobiology of the (not HLA class I predictors and large Sara endosomes during mented humoral immunity IgE-mediated acute phase laxis so) neonatal Fc receptor (FcRn) scale
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  • Engineered Erythrocytes Covalently Linked to Antigenic Peptides Can Protect Against Autoimmune Disease,” by Novalia Pishesha, Angelina M

    Engineered Erythrocytes Covalently Linked to Antigenic Peptides Can Protect Against Autoimmune Disease,” by Novalia Pishesha, Angelina M

    Correction IMMUNOLOGY AND INFLAMMATION Correction for “Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease,” by Novalia Pishesha, Angelina M. Bilate, Marsha C. Wibowo, Nai-Jia Huang, Zeyang Li, Rhogerry Dhesycka, Djenet Bousbaine, Hojun Li, Heide C. Patterson, Stephanie K. Dougan, Takeshi Maruyama, Harvey F. Lodish, and Hidde L. Ploegh, which appeared in issue 12, March 21, 2017, of Proc Natl Acad Sci USA (114: 3157–3162; first published March 7, 2017; 10.1073/pnas.1701746114). The authors note that the author name Rhogerry Dhesycka should instead appear as Rhogerry Deshycka. The corrected au- thor line appears below. The online version has been corrected. Novalia Pishesha, Angelina M. Bilate, Marsha C. Wibowo, Nai-Jia Huang, Zeyang Li, Rhogerry Deshycka, Djenet Bousbaine, Hojun Li, Heide C. Patterson, Stephanie K. Dougan, Takeshi Maruyama, Harvey F. Lodish, and Hidde L. Ploegh www.pnas.org/cgi/doi/10.1073/pnas.1705149114 CORRECTION www.pnas.org PNAS | April 25, 2017 | vol. 114 | no. 17 | E3583 Downloaded by guest on September 28, 2021 Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease Novalia Pisheshaa,b,c, Angelina M. Bilatea, Marsha C. Wibowoa,d, Nai-Jia Huanga, Zeyang Lia,c, Rhogerry Dhesyckaa,b, Djenet Bousbainea,c,d, Hojun Lia, Heide C. Pattersona, Stephanie K. Dougana, Takeshi Maruyamaa, Harvey F. Lodisha,b,d,1, and Hidde L. Ploegha,c,d,1,2 aWhitehead Institute for Biomedical Research, Cambridge, MA 02142; bDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142; cProgram in Cellular and Molecular Medicine, Boston Children’s Hospital, Boston, MA 02115; and dDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142 Contributed by Hidde L.