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Physiological and Metabolic Adaptations to Different Photoperiods: Effects of Obesity and Seasonal Fruit Consumption

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Physiological and Metabolic Adaptations to Different Photoperiods: Effects of Obesity and Seasonal Fruit Consumption PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó ADVERTIMENT. L'accés als continguts d'aquesta tesi doctoral i la seva utilització ha de respectar els drets de la persona autora. Pot ser utilitzada per a consulta o estudi personal, així com en activitats o materials d'investigació i docència en els termes establerts a l'art. 32 del Text Refós de la Llei de Propietat Intel·lectual (RDL 1/1996). Per altres utilitzacions es requereix l'autorització prèvia i expressa de la persona autora. En qualsevol cas, en la utilització dels seus continguts caldrà indicar de forma clara el nom i cognoms de la persona autora i el títol de la tesi doctoral. No s'autoritza la seva reproducció o altres formes d'explotació efectuades amb finalitats de lucre ni la seva comunicació pública des d'un lloc aliè al servei TDX. Tampoc s'autoritza la presentació del seu contingut en una finestra o marc aliè a TDX (framing). Aquesta reserva de drets afecta tant als continguts de la tesi com als seus resums i índexs. ADVERTENCIA. El acceso a los contenidos de esta tesis doctoral y su utilización debe respetar los derechos de la persona autora. Puede ser utilizada para consulta o estudio personal, así como en actividades o materiales de investigación y docencia en los términos establecidos en el art. 32 del Texto Refundido de la Ley de Propiedad Intelectual (RDL 1/1996). Para otros usos se requiere la autorización previa y expresa de la persona autora. En cualquier caso, en la utilización de sus contenidos se deberá indicar de forma clara el nombre y apellidos de la persona autora y el título de la tesis doctoral. 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Presentation of its content in a window or frame external to TDX (framing) is not authorized either. These rights affect both the content of the thesis and its abstracts and indexes. UNIVERSITAT ROVIRA I VIRGILI PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó Physiological and metabolic adaptations to different photoperiods: effects of obesity and seasonal fruit consumption Roger Mariné Casadó Doctoral Thesis Department of Biochemistry and Biotechnology 2018 UNIVERSITAT ROVIRA I VIRGILI PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó UNIVERSITAT ROVIRA I VIRGILI PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó UNIVERSITAT ROVIRA I VIRGILI PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó Roger Mariné Casadó Physiological and metabolic adaptations to different photoperiods: effects of obesity and seasonal fruit consumption Doctoral Thesis Directed by Prof. Lluís Arola Ferrer and Dr. Antoni Caimari Palou Department of Biochemistry and Biotechnology Tarragona 2018 UNIVERSITAT ROVIRA I VIRGILI PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó UNIVERSITAT ROVIRA I VIRGILI PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó UNIVERSITAT ROVIRA I VIRGILI PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó UNIVERSITAT ROVIRA I VIRGILI PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó AGRAÏMENTS GRÀCIES. Gràcies és la primera paraula que em ve al cap quan recordo aquest llarg però fugaç camí de tres anys i mig que amb el dipòsit d’aquesta tesi arriba a la seva fi. Quan reflexiono sobre tot el que he après com a persona i com a investigador, tota la gent que he tingut el plaer de conèixer i totes les experiències que ja formen part de la persona que sóc i que m’han ajudat a definir qui m’agradaria ser en un futur. En els inicis de qualsevol etapa és imprescindible trobar un estímul que et guiï i t’ajudi a escollir què és el millor per a tu. En el meu cas, quan vaig començar en el món de la recerca, aquest estímul va ser la meva gran amiga Esther. La teva paciència i les teves infinites ganes d’ajudar i compartir em van donar l’empenta per decidir-me a començar el camí que m’ha portat fins aquí. Moltíssimes gràcies per ser com ets i per ser-hi sempre. A la meva segona casa, al CTNS (ara Eurecat), a la família que s’ha anat fent cada cop més gran i que no para d’incorporar grans professionals però sobretot grans persones. A la Gertru, la Iris, l’Anna, la Cristina i la Bea, per fer-me companyia dia a dia fent que l’estrès es canalitzés a base de riure (i molt). A la Sílvia, el Juanma i la Yaiza, els tres herois del laboratori 100% disponibles per ajudar-me en tot moment però també per posar-nos a tots a ratlla (o no Juanma?). Al Joan, el Jaume i el Jordi (els grans J’s) per fer que el bon rotllo d’aquest grup encara creixi més. A la Noemí, per compartir aficions gastronòmiques i musicals i sobretot per tota l’ajuda que m’has ofert. Al Josep, per la teva paciència, confiança i ajuda durant aquests anys. A la Laura, l’Anna, l’Ignasi, l’Àurea, la Meri i a una llarguíssima llista de professionals que no acabaria mai d’anomenar, pel vostre suport i per fer d’aquest grup una gran família. A tots vosaltres, moltíssimes gràcies. Al grup de Nutrigenòmica per guiar-nos en tot moment al llarg del camí. Per compartir de forma contínua coneixements i pel feedback amb la gran quantitat UNIVERSITAT ROVIRA I VIRGILI PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó de doctorands que formem part d’aquest grup. A la Niurka i a la Rosa, per fer-nos la vida més fàcil a tots els doctorands i de quina manera! No em puc imaginar el grup sense elles i el seu bon rotllo continu. I especialment, vull agrair a la Cinta la immensa ajuda i la total disponibilitat que ha tingut al llarg del doctorat amb els integrants del projecte explora. Moltíssimes gràcies a tots. Al Lisard, l’Anna, l’Albert, l’Aïda i tota la resta de companys de batalles de la URV, que tot i no estar amb ells dia a dia en aquell despatx, ho heu fet tot més fàcil a base de sopars i festes de nadal i estiu, congressos bojos per Copenhagen amb la Chiku i el waffles danesos i moltes altres experiències brutals. Als que ja són doctors, als que han passat un estiu diferent com un servidor per arribar al final d’aquest recorregut i als que encara esteu en el camí, us estic molt agraït. Per sort, tot i començar com a fill únic en el món de les tesis doctorals en aquest centre, poc a poc van arribar altres “germans” sense els quals no hagués gaudit ni la meitat de tot això: Els grans Cara-anchoas. A l’Eugènia, per les estones inoblidables al laboratori que tant ens han fet falta aquests últims mesos. A l’Héctor, per animar el laboratori cada dia, compartir bromes, preocupacions i aficions. Per ser un crack i punt. A la Kathe, l’ex-doctorand infiltrada, per seguir ajudant-me en tot moment com porta fent durant molts anys. A l’Andreu, per haver tingut la paciència d’aguantar-me (més ben dit, aguantar-nos mútuament), durant aquests últims mesos compartint despatx romàntic. Ets un grande! I a la Guirro, amb la que “ens coneixem des de primer de carrera però som amics des de segon”, per estar des del primer dia de pràctiques fins a l’últim dia de tesi al meu costat. Moltíssimes gràcies a tots! El fet d’haver viscut la millor experiència de la meva vida durant la realització del doctorat, li dóna molt més pes a aquesta tesi. La decisió de marxar al Quebec durant tres mesos al grup del Dr. André Marette no va poder ser més encertada. Thank you André for giving me the opportunity to work with such a professional research group. Also thanks to Geneviève, the kindest person that I have ever UNIVERSITAT ROVIRA I VIRGILI PHYSIOLOGICAL AND METABOLIC ADAPTATIONS TO DIFFERENT PHOTOPERIODS: EFFECTS OF OBESITY AND SEASONAL FRUIT CONSUMPTION Roger Mariné Casadó met. You trusted me and treated me just like one of your group since the first day. Trish, Kerstin, Phil, Michael, Bruno, Marie Julie and Vanessa H merci pour tout! I promise that I will improve my French! To Béatrice, Noémie, Laurence, Gabriel and Ida, the best labmates that I could ever asked, thanks for your help.
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