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Cancer Research in Switzerland Zurich Open Repository and Archive University of Zurich Main Library Strickhofstrasse 39 CH-8057 Zurich www.zora.uzh.ch Year: 2014 The importance of team work Fuchs, B Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: https://doi.org/10.5167/uzh-106014 Published Research Report Published Version Originally published at: Fuchs, B (2014). The importance of team work. Bern, Schweiz: Krebsliga Schweiz. Cancer Research in Switzerland A publication of the Swiss Cancer Research foundation, the Swiss Cancer League and the cantonal cancer leagues on their funded research projects 2013 Edition 2014 Imprint © Swiss Cancer Research foundation (SCR) and Swiss Cancer League (SCL) All rights reserved by the Scientific Office of the Swiss Cancer League and the Swiss Cancer Research foundation, including the right to reproduce this publication or portions in any form. Publisher and information: Swiss Cancer League Scientific Office Effingerstrasse 40 P. O. Box 8219 CH-3001 Bern Tel. +41 31 389 91 16 Fax +41 31 389 91 62 [email protected] www.swisscancer.ch /research Publication date: November 2014 English edition: 400 Ex. German edition: 4700 Ex. French edition: 1300 Ex. Responsible: Rolf Marti, PhD Head Scientific Office, Swiss Cancer League, Bern Director Swiss Cancer Research foundation, Bern Project management and editing: Kurt Bodenmüller, lic. phil. nat. Scientific Office Communications manager Swiss Cancer League and Swiss Cancer Research foundation, Bern Editing: Wolfgang Wettstein Public Relations Consultant BR-SPRV, Zurich [email protected] Editorial collaboration: Stéphanie Buvelot Frei, PhD, Scientific assistant in the Scientific Office, Swiss Cancer League and the Swiss Cancer Research foundation, Bern English translation: Ellen Russon, East Sandwich, Massachusetts, USA, www.ellenrusson.com Images: Eva-Fiore Kovacovsky, Amsterdam/Berlin Design: atelierrichner.ch Print: Ast & Fischer AG, Wabern This edition of the report “Cancer Research in Switzerland 2014” as well as the 2013, 2012, 2011, 2009, 2006 and 2004 editions can be downloaded as PDF files at: www.swisscancer.ch /researchreport This publication is also available in German and French at: www.swisscancer.ch /research Eva-Fiore Kovacovsky (*1980) Born in Bern, lives and works in Amsterdam and Berlin. Eva-Fiore Kovacovsky examines phenomena in the world of plants, which she collects according to her own criteria and uses as a starting point in her artworks. Kovacovsky works with several different reproduction techniques and methods of photography. She abstracts, manipulates, arranges, and reproduces parts of plants and in this way generates artworks that deal with our own perception. For her Fotogramme series shown here, Kovacovsky works with leaves that she has collected because of their distinctive patterns of perforations. She uses the leaves with holes eaten into them by beetles and caterpillars as negatives, places them in the negative carrier of a colour photographic enlarger, and exposes them on photographic paper. She constructs intuitive images by working in a playful way with different enlarging lenses, image details, multiple exposures, shifting of the filters in the colour mixing head, and photographic paper. www.kovacovsky.com Eva-Fiore Kovacovsky’s work is in public and private collections. She is represented by the STAMPA gallery in Basel (www.stampa-galerie.ch). All images courtesy of Eva-Fiore Kovacovsky and STAMPA, Basel At the request of the artist, the original titles of her works have not been translated. Cancer Research in Switzerland Table of contents 4 Editorial Thomas Cerny and Jakob R. Passweg 6 Funding internationally top-level cancer research Rolf Marti 20 Excellent marks for research funding Stéphanie Buvelot Frei and Kurt Bodenmüller 24 Partner organizations and committees Kurt Bodenmüller 28 The Scientific Committee 32 Prizes for outstanding achievements in cancer research and fighting cancer 34 National Strategy Against Cancer 2014 – 2017 Health services research Rolf Marti and Kurt Bodenmüller 42 Research funding by the cantonal and regional cancer leagues Luc Perrin, Geneva 44 List of supported funded research projects and institutions in 2013 49 Presentation of supported funded research projects and institutions in 2013 Basic biomedical research 64 Genome stability, DNA repair and cancer Primo Schär, Basel 69 List of completed research projects in 2013 71 Presentation of completed research projects in 2013 83 List of approved research projects in 2013 85 Presentation of approved research projects in 2013 Clinical research 94 Research and development in tumour surgery: The importance of team work Bruno Fuchs, Zurich 100 List of completed research projects in 2013 102 Presentation of completed research projects in 2013 107 List of approved research projects in 2013 111 Presentation of approved research projects in 2013 Psychosocial research 121 Web-based psychological support for people with cancer Sibil Tschudin, Judith Alder and Astrid Grossert, Basel 126 Completed research project in 2013 126 Presentation of completed research project in 2013 127 List of approved research projects in 2013 128 Presentation of approved research projects in 2013 Epidemiological research 132 Cancer survivors: a fast growing segment of the population Silvia M. Ess and Christian Herrmann, St. Gallen 139 List of completed research projects in 2013 140 Presentation of completed research projects in 2013 143 List of approved research projects in 2013 144 Presentation of approved research projects in 2013 Editorial 4 Thanks to donations of more than 20 million francs, in 2013 the Swiss Cancer Research foundation, the Swiss Cancer League, and the cantonal and regional cancer leagues invested another new record sum in cancer research. This is a wonderful result not only in quantitative terms; the funding of research and also the funded research projects achieved satisfying re- sults also in terms of quality. Research funding by the Swiss Cancer Research foun- dation and the Swiss Cancer League was assessed comprehensively in 2013 by means of an independ- ent external evaluation. As a part of the evaluation, more than 400 publications produced by funded re- search projects from 1998 to 2006 were rated. The results showed that the researchers especially in basic biomedical, translational, and epidemiological research published many high-quality and important papers that achieved top ratings in a comparison with nine European funding institutions. The results of a survey of the researchers were also positive: The majority of the researchers rated the commitment of the two funding institutions to their own research activities as high to very high and to cancer research in Switzerland in general as positive to very positive. Nearly nine of ten survey respond- ents stated that the grant application process from submission to review was transparent, fair, and of high-quality. And also a comprehensive analysis by a group of six independent, internationally renowned experts gave excellent marks for central aspects such as research promotion, quality assurance, monitor- ing, structures, and resources. The experts were particularly impressed by the quality of the work of the Scientific Committee, the group of 17 experts who review approximately 170 to 180 ap- plications for grants and bursaries each year accord- ing to defined criteria and international standards. Thomas Cerny Jakob R. Passweg 5 They thus perform an extremely valuable service for the Swiss Cancer Research foundation and the Swiss Cancer League. Thanks to the work of the Scientific Committee, only the highest quality and most prom- Prof. Thomas Cerny, MD ising research projects are funded. We therefore ex- President of the Swiss Cancer Research tend sincere thanks to all members of the Scientific foundation Committee and especially to Prof. Martin F. Fey, MD, who has served as president of the Scientific Com- mittee since 2006 and will be stepping down at the end of this year. Prof. Nancy Hynes, PhD, molecular biologist and breast cancer specialist, has been elected the new president and will take office at the Prof. Jakob R. Passweg, MD start of 2015. President of the Swiss Cancer League We would like to express our heartfelt thanks to all charitable donors for your support. Your generosity and loyalty make it possible for us to fund outstand- ing cancer research aiming to continue to improve chances of survival and quality of life of patients with cancer. Funding internationally top-level cancer research 6 In 2013 the Swiss Cancer Research foundation and great advances in diagnosis and treatment. To- (SCR), the Swiss Cancer League (SCL), and eight day, more than half of persons with cancer – approx- cantonal cancer leagues (CCL) gave a total of imately 37,000 new cancer cases are diagnosed each 20.4 million francs to cancer research in Switzer- year – can be treated successfully. land – which was again a new record sum. Also gratifying are the results of an independent exter- Nevertheless, each year approximately 16,000 pa- nal evaluation that gave the work of the SCR and tients die of cancer, and with some types of cancer, the SCL in research funding and also the quality such as pancreatic cancer or brain tumours, the of the funded projects excellent marks. We thank chances of successful treatment are low. Further all of the charitable donors for their trust and advances in the fight against cancer are therefore ur- support. gently needed – not only to
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