Product Datasheet

YWHAG antibody

Catalog No: #38549

Orders: [email protected] Description Support: [email protected]

Product Name YWHAG antibody

Host Species Rabbit

Clonality Polyclonal

Purification Antibodies were purified by affinity purification using immunogen.

Applications WB,IHC

Species Reactivity Human,Mouse,Rat

Specificity The antibody detects endogenous level of total YWHAG antibody.

Immunogen Type Peptide

Immunogen Description A synthetic peptide of human YWHAG.

Target Name YWHAG

Other Names 14-3-3GAMMA

Accession No. Swiss-Prot#: P61981NCBI ID: 7532

SDS-PAGE MW 28kd

Concentration 1.0mg/ml

Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02%

sodium azide and 50% glycerol.

Storage Store at -20°C

Application Details

WB 1:500 - 1:2000IHC 1:50 - 1:200

Images

Western blot analysis of extracts of various cell lines, using YWHAG at 1:500 dilution.

Background

This gene product belongs to the 14-3-3 family of which mediate by binding to phosphoserine-containing proteins. This highly conserved family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Note: This product is for in vitro research use only and is not intended for use in humans or animals.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2