Product Datasheet YWHAG antibody Catalog No: #38549 Orders: [email protected] Description Support: [email protected] Product Name YWHAG antibody Host Species Rabbit Clonality Polyclonal Purification Antibodies were purified by affinity purification using immunogen. Applications WB,IHC Species Reactivity Human,Mouse,Rat Specificity The antibody detects endogenous level of total YWHAG antibody. Immunogen Type Peptide Immunogen Description A synthetic peptide of human YWHAG. Target Name YWHAG Other Names 14-3-3GAMMA Accession No. Swiss-Prot#: P61981NCBI Gene ID: 7532 SDS-PAGE MW 28kd Concentration 1.0mg/ml Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage Store at -20°C Application Details WB 1:500 - 1:2000IHC 1:50 - 1:200 Images Western blot analysis of extracts of various cell lines, using YWHAG at 1:500 dilution. Background This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Note: This product is for in vitro research use only and is not intended for use in humans or animals. Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2.