Research J. Pharm. and Tech. 12(2): February 2019 ISSN 0974-3618 (Print) www.rjptonline.org 0974-360X (Online) RESEARCH ARTICLE Assessment on Antimicrobial Activity of Pergularia daemia Leaf Extract Devika R*, Chozhavendhan S, Karthigadevi G, Shalini Chauhan Department of Biotechnology, Aarupadai Veedu Institute of Technology, Vinayaka Missions Research Foundation (Deemed to be University), Paiyanoor – 603104. *Corresponding Author E-mail:
[email protected] ABSTRACT: Over the past few decades, curing of diseases are under threat as many medicines and drugs produce toxic reactions. Nowadays 61% of new drugs has been developed using natural phytochemicals in curing many diseases. Present investigation is an attempt to assess the antimicrobial activity of Pergularia daemia and to evaluate the potential against antibiotics. In the present study, P.daemia proved to have efficient phytochemicals which created distinct zone of inhibition against bacterial strains. KEYWORDS: Antibacterial, zone of inhibition, resistance, susceptible, phytochemicals. INTRODUCTION: The whole plant is slender, hispid, fetid–knelling, Ayurveda an ancient system of Indian medicine which Leaves opposite, membrananous, 3-9 cm long and are using number of phytochemicals extracted from broadly Ovate, orbicular or deeply cordate, acute or plant sources for the treatment of various diseases. short acuminate at apex, petioles 2-9 cm long. Flowers Modern medicine has expanded the use of herbal greenish yellow or dull white tinged with purple, borne medicine which has lead to the assurance of safety, in axillary, long peduncled, drooping clusters. Fruits quality and efficacy1. The foremost concern is that the lanceolate, long pointed about 5 cm, long covered with synthetic drugs show sensitive reaction and other soft spines and seeds are pubescent broadly orate8.