Ecole Nationale Veterinaire De Lyon

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Ecole Nationale Veterinaire De Lyon ECOLE NATIONALE VETERINAIRE DE LYON Année 2010 - Thèse n° Quel avenir pour l’homéopathie et la phytothérapie en pratique vétérinaire courante ? Etat des lieux de la recherche scientifique. THESE Présentée à l’UNIVERSITE CLAUDE-BERNARD - LYON I (Médecine - Pharmacie) et soutenue publiquement le ….. pour obtenir le grade de Docteur Vétérinaire par Floriane COMBRE Née le 21 août 1984 à Beaumont (63) - 2 - - 3 - - 4 - A notre jury de thèse, A Monsieur le Professeur Calender, De la Faculté de Médecine de Lyon, Qui nous a fait l’honneur d’accepter la présidence de notre jury de thèse. Qu’il trouve ici l’expression de nos hommages respectueux. A Madame le Docteur Prouillac, De l’Ecole Nationale Vétérinaire de Lyon, Qui a accepté de diriger ce travail et nous a guidé avec compétence, gentillesse et disponibilité. Sincères remerciements. A Madame le Docteur Egron-Morand, De l’Ecole Nationale Vétérinaire de Lyon, Qui nous a fait l’honneur de juger notre travail et de participer à notre jury de thèse, Hommages respectueux - 5 - - 6 - Table des matières TABLE DES MATIERES -------------------------------------------------------------------------------- - 7 - TABLE DES ILLUSTRATIONS ET TABLEAUX ---------------------------------------------------- - 11 - PREMIERE PARTIE : L’HOMEOPATHIE --------------------------------------------------------- - 15 - I. L’HOMEOPATHIE : ASPECTS GENERAUX ------------------------------------------------ - 15 - A. HISTORIQUE -------------------------------------------------------------------------------------- - 15 - 1. Hippocrate et Paracelse : les précurseurs ------------------------------------------ - 15 - 2. Hahnemann -------------------------------------------------------------------------------- - 16 - 3. L’homéopathie moderne --------------------------------------------------------------- - 17 - B. LES GRANDS PRINCIPES DE L’HOMEOPATHIE ---------------------------------------------------- - 19 - 1. Le principe de similitude ---------------------------------------------------------------- - 19 - 2. Le principe d’infinitésimalité----------------------------------------------------------- - 21 - 3. Le principe d’individualité -------------------------------------------------------------- - 22 - C. L’HOMEOPATHIE EN PRATIQUE ------------------------------------------------------------------ - 23 - 1. Le concept de maladie ------------------------------------------------------------------ - 23 - 2. La connaissance du patient ------------------------------------------------------------ - 24 - a) Le terrain sain --------------------------------------------------------------------------------- - 24 - (1) La constitution de l’individu ------------------------------------------------------------ - 24 - (2) Le tempérament et le type sensible ----------------------------------------------------- 26 b) Les diathèses ------------------------------------------------------------------------------------- 26 D. LE MEDICAMENT HOMEOPATHIQUE ------------------------------------------------------------- 29 1. La préparation --------------------------------------------------------------------------------- 29 a) Les matières premières ------------------------------------------------------------------------ 29 (1) Les substances d’origine animale -------------------------------------------------------- 29 (2) Les substances d’origine végétale ------------------------------------------------------- 29 (3) Les substances d’origine minérale ------------------------------------------------------- 29 (4) La biothérapie, ou nosodes ---------------------------------------------------------------- 30 (5) L’organothérapie ----------------------------------------------------------------------------- 30 (6) L’isothérapie ---------------------------------------------------------------------------------- 30 b) Les procédés de fabrication ------------------------------------------------------------------- 30 (1) L’extraction des principes actifs ---------------------------------------------------------- 30 (2) La déconcentration et la dynamisation ------------------------------------------------- 31 (a) La déconcentration, ou dilution ------------------------------------------------------- 31 (i) La dilution Korsakovienne, ou technique en flacon unique ------------------ 31 (ii) La dilution Hahnemannienne, ou technique en flacons séparés ----------- 31 (b) La dynamisation -------------------------------------------------------------------------- 33 2. La galénique homéopathique ------------------------------------------------------------- 33 E. LA CONSULTATION HOMEOPATHIQUE -------------------------------------------------------------- 35 1. Commémoratifs et anamnèse ------------------------------------------------------------- 35 2. Examen clinique ------------------------------------------------------------------------------- 35 3. Synthèse clinique et anamnestique : la valorisation et la hiérarchisation ----- 36 a) Valorisation --------------------------------------------------------------------------------------- 36 b) Hiérarchisation ----------------------------------------------------------------------------------- 36 - 7 - 4. Le choix du médicament homéopathique ---------------------------------------------- 37 a) Le choix du médicament ----------------------------------------------------------------------- 37 b) Le choix de la dynamisation et la posologie ----------------------------------------------- 37 c) La rédaction de l’ordonnance ---------------------------------------------------------------- 37 5. Le suivi du patient ---------------------------------------------------------------------------- 38 a) Les critères d’amélioration -------------------------------------------------------------------- 38 b) Les différentes évolutions possibles -------------------------------------------------------- 38 6. La guérison ------------------------------------------------------------------------------------- 39 II. LA RECHERCHE EN HOMEOPATHIE -------------------------------------------------------- 41 A. LE FONCTIONNEMENT DU MEDICAMENT HOMEOPATHIQUE --------------------------------------- 41 1. Les théories au niveau moléculaire ------------------------------------------------------ 41 a) L’hormesis et la théorie de l’adaptation --------------------------------------------------- 41 b) La structure et la mémoire de l’eau --------------------------------------------------------- 41 (1) La mémoire de l’eau ------------------------------------------------------------------------ 42 (2) L’épitaxie --------------------------------------------------------------------------------------- 43 2. Les théories concernant le mode d’action --------------------------------------------- 44 a) L’importance de la structure du médicament homéopathique ---------------------- 44 b) L’hypothèse d’une action homéopathique via le système voméro-nasal ---------- 44 B. LES ESSAIS CLINIQUES EN HOMEOPATHIE ----------------------------------------------------------- 47 1. La recherche des effets d’une substance ----------------------------------------------- 47 2. L’efficacité thérapeutique des médicaments homéopathiques ------------------ 49 a) Les domaines d’étude classiques en homéopathie -------------------------------------- 49 (1) Traitement des troubles liés au stress et à l’anxiété -------------------------------- 49 (2) Activité anti-inflammatoire et au niveau de l’appareil ambulatoire ------------- 50 (a) La recherche de nouvelles solutions en thérapeutique anti-inflammatoire 50 (b) Deux exemples d’études pilotes en pathologie de l’appareil musculo- squelettique 52 (i) Une nouvelle piste pour le traitement de la fibromyalgie -------------------- 52 (ii) Une étude expérimentale inédite sur la reconstruction osseuse ---------- 52 (3) Action sur les problèmes dermatologiques -------------------------------------------- 53 (a) De nouvelles perspectives pour le traitement du prurit associé à une dermatite atopique --------------------------------------------------------------------------------------- 53 (b) Un nouveau traitement pour le complexe granulome éosinophilique félin 54 (4) Le traitement des pathologies de la reproduction ----------------------------------- 54 (a) Le traitement de la lactation de pseudo-gestation chez la chienne ---------- 54 (b) Le traitement des troubles de la reproduction chez les animaux de rente - 55 (i) L’induction de l’œstrus en élevage bovin ---------------------------------------- 55 (ii) La gestion des mammites en élevage --------------------------------------------- 56 (5) Action sur le rendement et les pathologies d’élevage ------------------------------ 58 (a) La prévention et le traitement des diarrhées -------------------------------------- 58 (b) Effet des traitements homéopathiques sur les performances zootechniques 59 (6) Activité antiparasitaire --------------------------------------------------------------------- 61 (a) La gestion du parasitisme dans le troupeau ---------------------------------------- 61 (b) La gestion du parasitisme cellulaire -------------------------------------------------- 62 b) Domaines de recherche plus récents ------------------------------------------------------- 62 (1) Activité anticancéreuse -------------------------------------------------------------------- 62 (2) Endocrinologie-------------------------------------------------------------------------------- 64 C. LA PERCEPTION DE LA MEDECINE HOMEOPATHIQUE ----------------------------------------------- 65 1. Qui consulte en homéopathie
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