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NSV 2018: Gran Guardia Palace, Verona, Italy

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NSV 2018: Gran Guardia Palace, Verona, Italy 17th NSV2018 Verona ITALY June 17-22, 2018 General Information MEETING ORGANIZERS Dominique Garcin: University of Geneva, Switzerland Grazia Cusi: University of Siena, Siena, Italy Wendy Barclay: Imperial College, London, UK Paul Duprex: Boston University, Boston, USA Sean Whelan: Harvard Medical School, Boston, USA The organizers gratefully acknowledge David Zenaty and Keith Ketterer, Harvard Medical School for administrative and website support USEFUL NUMBERS Administrative Secretariat: Local Secretariat: MCI Geneva Iantra 9, rue Pré-Bouvier Piazza Donatori di Sangue 5 1242 Satigny / Geneva 37124 Verona Switzerland Italy Onsite Phone: +41 765714224 Email: [email protected] Emergency: 118 Local Police: 112 / 113 Ambulance: 118 History of NSV The first meeting, entitled “The biology of large RNA viruses” was organized by Richard D. Barry and Brian W. J. Mahy in 1969, Cambridge England. A symposium volume was published following this congress and includes presentations on negative-strand RNA viruses and retroviruses. The meeting predated the discovery of reverse transcriptase and the recognition that the negative-strand RNA viruses contain an RNA polymerase within the virion. This is the premier meeting in the field of negative strand RNA viruses. The conference is limited in size to approximately 400 participants, with presentations that cover all aspects of the fundamental biology of negative strand RNA viruses. This is the 17th meeting and we continue in the spirit of previous conferences and there will be no invited speakers or concurrent sessions. NSV 1969: Pembroke College, Cambridge, UK NSV 1973: King’s College, Cambridge, UK NSV 1977: King’s College, Cambridge, UK NSV 1980: St. Thomas, Virgin Islands, USA NSV 1982: Hilton Head, NC, USA NSV 1985: Robinson College, Cambridge, UK NSV 1988: Palais des Congrès, Dinard, France NSV 1991: Hibernian Hall, Charleston, SC, USA NSV 1994: Hotel Estoril Sol, Estoril, Portugal NSV 1997: Trinity College, Dublin, Ireland NSV 2000: Palais Montcalm, Québec City, Canada NSV 2003: Palazzo dei Congressi, Pisa, Italy NSV 2006: Hospederia de Fonseca, Salamanca, Spain NSV 2010: Concertgebouw, Bruges, Belgium NSV 2013: Palacio de Congresos, Granada, Spain NSV 2015: Università di Siena, Siena, Italy NSV 2018: Gran Guardia Palace, Verona, Italy The scientific program is complemented by a vibrant social program designed to foster interactions among all of the attendees, welcome newcomers to the field, strengthen our community and provide life-long memories. Future of NSV The organizing committee would like to encourage you to visit Poster P000 so that you can have input on the future of NSV. This poster will remain up throughout the meeting and we ask that you visit the poster and talk to the organizers. Among the topics we seek feedback on are: • Formation of a non-profit organization whose sole objective is the organization of the Negative Strand Virus meeting • Membership of the non-profit organization • Culture of the meeting • Ensuring access to all members of the community Image courtesy of Rebekah Dumm and Nick Heaton, Duke University, USA Verona In fair Verona, where we lay our scene … Roman theater duomo piazza Erbe Juliet’s balcony arena piazza Bra Gran Guardia Social Program WELCOME RECEPTION The welcome reception will take place on the terrace of the Gran Guardia Palace from 19:00-22:00 on Sunday, June 17. Come and see the view of the Arena, meet old and new friends and enjoy some Italian hospitality. WALKING TOUR OF VERONA The historic city of Verona was founded in the 1st Century BC. Verona has preserved a remarkable number of monuments from antiquity, the medieval and Renaissance periods, and represents an outstanding example of a military stronghold. So splendid is the city that its reputation alone inspired Shakespeare to set two plays here. We will learn about the city’s past as we wander the charming streets on Monday, June 18. Social Program DINNER BY THE LAKE A trip to this region would be incomplete without visiting Lake Garda – the largest lake in Italy. Take time to walk around the picturesque town of Lazise and then have an aperitif followed by a buffet at the Dogana Veneta. Buses leave from the Gran Guardia at 18:30 on Tuesday, June 19. GALA DINNER The Gala Dinner has been a highlight of the NSV social program since its inception. Join us at beautiful Villa Arvedi – built in the 17th Century – and frescoed by the French painter Ludovico Dorigny. Buses leave from the Gran Guardia at 18:45 on Thursday, June 21. Week at a glance PROGRAM SUNDAY MONDAY TUESDAY WEDNESDAY THURSDAY FRIDAY 9 BREAKING EXPRESSING BUILDING DAMAGING & & & & EMERGING 10 ENTERING MULTIPLYING ESCAPING SPREADING & EVOLVING COFFEE & POSTERS 11 COFFEE SUPPRESSING FIGHTING EMERGING BREAKING & BUILDING & 12 & & CONQUERING & RESPONDING EVOLVING ENTERING ESCAPING 13 LUNCH & POSTERS LUNCH 14 SUPPRESSING FIGHTING & & EXPRESSING DAMAGING CONQUERING RESPONDING 15 & & MULTIPLYING SPREADING COFFEE & POSTERS 16 SUPPRESSING FIGHTING & & REGISTRATION 17 EXPRESSING CONQUERING DAMAGING RESPONDING & & MULTIPLYING SPREADING 18 19 WALKING WELCOME TOUR LAKE GARDA 20 RECEPTION DOGANA 21 GALA DINNER GRAN FREE EVENING VENETA FREE EVENING VILLA ARVEDI 22 GUARDIA 23 00 Sunday June 17 14:00-18:30 Registration: Gran Guardia Piazza Bra, 1 37121 Verona Poster Session One: P000, P230, P001-P123 Monday, June 18 and Tuesday June 19 Poster dismantling Tuesday, June 19, at the end of the session Poster Session Two: P000, P230, P124-P249 Wednesday, June 20 and Thursday June 21 Poster dismantling Thursday, June 21, at the end of the session 19:00-22:00 Welcome Reception at Gran Guardia Session One Monday June 18 BREAKING AND ENTERING 08:50-09:00 WELCOME TO NSV2018 09:00-09:10 Anne MOSCONA and Kartik CHANDRAN Chairpersons' remarks 1 09:10-09:30 Silke STERTZ HUMAN LEUCOCYTE ANTIGEN DR (HLA-DR) HOMOLOGS ARE CROSS- SPECIES ENTRY RECEPTORS FOR BAT INFLUENZA VIRUSES. UNIVERSITY OF ZURICH, Zurich, Switzerland 2 09:30-09:50 Roberto CATTANEO NECTINS TRANSFER CYTOPLASM BETWEEN CELLS AND CAN SPREAD MEASLES VIRUS TO NEURONS MAYO CLINIC, Rochester, United States 3 09:50-10:00 Donald BENTON STRUCTURE OF FULL-LENGTH INFLUENZA HAEMAGGLUTININ THE FRANCIS CRICK INSTITUTE, London, United Kingdom 4 10:00-10:10 Aurelie ALBERTINI STRUCTURAL BASIS OF LOW-DENSITY LIPOPROTEIN RECEPTOR RECOGNITION BY VSV GLYCOPROTEIN CNRS, GIF SUR YVETTE, France 5 10:10-10:20 Eva MITTLER DELINEATING INTERACTION OF FILOVIRAL GP WITH ITS ENDOSOMAL RECEPTOR NPC1 BY IN SITU PROXIMITY LIGATION ALBERT EINSTEIN COLLEGE OF MEDICINE, New York, United States 6 10:20-10:30 Rohit JANGRA HOST FACTOR REQUIRED FOR IN VIVO PATHOGENICITY OF NEW WORLD HANTAVIRUSES ALBERT EINSTEIN COLLEGE OF MEDICINE, Bronx, United States COFFEE BREAK WITH POSTERS 10:30-11:30 MondayBREAKING AND ENTERINGJune 18 7 11:30-11:50 Rebecca DUTCH ANCHORING THE SPRING: THE ROLE OF TRANSMEMBRANE DOMAIN INTERACTIONS IN VIRAL FUSION PROTEIN FUNCTION UNIVERSITY OF KENTUCKY, Lexington, United States 8 11:50-12:10 Hector AGUILAR-CARRENO UNCOVERING A NEW PARAMYXOVIRAL ATTACHMENT GLYCOPROTEIN ROLE BEYOND FUSION TRIGGERING CORNELL UNIVERSITY, Ithaca, United States 9 12:10-12:30 Nicole TISCHLER HANTAVIRUS GC HOMOMERIC DIMER AND TRIMER CONTACTS DIRECT SPIKE DISSOCIATION AND MEMBRANE FUSION FUNDACIÓN CIENCIA PARA LA VIDA, Santiago, Chile 10 12:30-12:40 Ilona RISSANEN ANTIGENIC ARRANGEMENT OF THE DYNAMIC HANTAVIRAL SURFACE UNIVERSITY OF HELSINKI, Helsinki, Finland 11 12:40-12:50 Chiara FEDELI RECEPTOR TYROSINE KINASES ARE PROMISING TARGETS IN LASSA VIRUS ANTIVIRAL THERAPY CHUV, Lausanne, Switzerland LUNCH 12:50-14:20 Session Two EXPRESSING AND MULTIPLYING 14:20-14:30 Ervin FODOR, Ben HALE and Rachel FEARNS Chairpersons' remarks 12 14:30-14:50 Juan REGUERA STRUCTURE AND FUNCTION OF PHENUIVIRIDAE CAP-SNATCHING ENDONUCLEASES INSERM, Marseille, France 13 14:50-15:10 Sean WHELAN MECHANISM OF POLYMERASE REGULATION BY A 5’ HOOK LIKE STRUCTURE IN THE GENOMIC RNA OF MACHUPO VIRUS. HARVARD MEDICAL SCHOOL, Boston, United States 14 15:10-15:20 Haitan FAN STRUCTURAL INSIGHTS INTO THE MECHANISMS OF INFLUENZA A VIRUS RNA REPLICATION UNIVERSITY OF OXFORD, Oxford, United Kingdom 15 15:20-15:30 Akiko MAKINO TRANSLATIONAL REGULATION OF BORNA DISEASE VIRUS KYOTO UNIVERSITY, Kyoto, Japan 16 15:30-15:50 Jianrong LI VIRAL N6-METHYLADENOSINE PROMOTES REPLICATION AND GENE EXPRESSION OF PNEUMOVIRUSES THE OHIO STATE UNIVERSITY, Columbus, United States COFFEE BREAK AND POSTERS 15:50-16:50 EXPRESSING AND MULTIPLYING 17 16:50-17:10 Christopher BASLER PROTEOMIC ANALYSIS IDENTIFIES HUMAN E3 UBIQUITIN LIGASE RBBP6 AS A NEGATIVE REGULATOR OF EBOLA VIRUS INFECTION GEORGIA STATE UNIVERSITY, Atlanta, United States 18 17:10-17:20 Simone BACH ADVANCED ANALYSES ON THE ROLE OF VP30 AND RNA STRUCTURES IN EBOLA VIRUS TRANSCRIPTION PHILIPPS-UNIVERSITÄT MARBURG, Marburg, Germany 19 17:20-17:40 Andrew MEHLE REPURPOSING CANONICAL ANTIVIRAL RESPONSES TO PROMOTE TRANSLATION OF INFLUENZA VIRUS MESSENGER RNAs UNIVERSITY OF WISCONSIN MADISON, Madison, United States 20 17:40-17:50 Jason LONG BINDING TO ANP32 IS REQUIRED BUT NOT SUFFICIENT FOR INFLUENZA A VIRUS POLYMERASE ACTIVITY IMPERIAL COLLEGE LONDON, London, United Kingdom 21 17:50-18:10 Anice LOWEN INCOMPLETE GENOMES OF INFLUENZA A VIRUS DRIVE ABUNDANT REASSORTMENT Emory University, Atlanta, United States GUIDED TOURS OF VERONA 18:30 #NSV2018 WALKING TOUR OF VERONA Guided tours leave from the front of Gran Guardia from 18:30-19:00 Tonight we explore the city and a highlight will be the famous Juliet’s balcony. • Band-Aids and a Sharpie are in your bag! • suggested activity see photograph below • meet someone new and share the results broadly with the #NSV2018 community on social media or email them to [email protected]. • If you don’t tweet what better time to start … enjoy! Tuesday June 19 EXPRESSING AND MULTIPLYING 22 09:00-09:20 Rachel FEARNS DIFFERENCES BETWEEN TRANSCRIPTION AND REPLICATION INITIATION MECHANISMS OF THE PNEUMO- AND PARAMYXOVIRIDAE BOSTON UNIVERSITY SCHOOL OF MEDICINE, Boston, United States 23 09:20-09:40 Richard RANDALL NEXT GENERATION SEQUENCING REVEALS NOVEL ASPECTS OF PARAMYXOVIRUS TRANSCRIPTION AND REPLICATION AND THE SWITCH BETWEEN ACUTE AND PERSISTENT INFECTIONS.
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