DOCSLIB.ORG

View Annual Report

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
View Annual Report ANNUAL REPORT 2016 Bringing breakthrough pioneering therapies to patients with life-threatening diseases www.celyad.com CELYAD ANNUAL REPORT 2016 Table of contents Letter of the Chairman . 04 Letter of the CEO . 06 Our Mission . 08 Key figures 2016 . 09 2016 Key milestones . 10 Cancer: a collection of more than 200 different individual diseases . 12 Key facts & figures about cancer worldwide . 13 Celyad’s lead oncology drug candidate: the CAR-T NKR-2 cellular immunotherapy . 16 CAR-T NKR-2: a safe immunotherapy . 18 Reaching the effective dose-level of CAR-T NKR-2 cells with the THINK study . 20 A robust immuno-oncology pipeline . 22 Our partners in immuno-oncology . 24 Celyad’s intellectual property portfolio immunotherapy . .. 26 Cardiology: How to best prepare for CHART-2? . 28 Cardiology: partners & IP portfolio . 29 Making the Impossible Possible . 30 Celyad’s Key HR facts & figures . 31 Celyad’s team is all about passion . 32 Corporate governance . 34 Our senior leadership team . 35 Information for shareholders . 36 Finance / Analyst coverage & contacts & glossary . .. 37 Letter of the Chairman Dear Shareholders, 2016 has been transformational for your company which, in only a year, has positioned itself as a serious international player in the CAR-T field, one of the most promising approaches for cancer treatment. Beginning of 2015, we felt important to diversify our clinical portfolio, building on our core expertise in cell therapy to explore new therapeutic areas for major unmet medical needs, such as cancer. Michel Lussier Celyad thus started to scout in the US, searching for the hidden gem that would — CHAIRMAN OF THE BOARD allow the company to make a difference in the immuno-oncology field. We acquired a technology invented by Prof. Charles Sentman at Dartmouth College, a CAR-T therapy based on a unique construct using the NKG2D receptor. This is now a breakthrough asset for the company and a major promise for the patients. While having a fully integrated know-how and equipment, highly skilled people, a very disruptive technology and a strong intellectual property, we needed then to raise sufficient financial resources to undertake rapidly our clinical program and build our presence in the USA, the CAR-T homeland. And that is exactly what we did. In 18 months, we raised more than $130 million, introduced Celyad on NASDAQ, we have opened an office and built a seasoned team in the Boston area, we have launched and successfully completed a Phase Ia trial and we have signed strategic collaborations with world-class academic and industrial partners. Last but not the least, we have initiated the THINK Phase I trial, taking a global lead in CAR-T for solid tumors. 04 CELYAD • ANNUAL REPORT 2016 “We made the right decisions at the right time, moving on to the next chapter of our company history. 2017 will be a very exciting year for Celyad, which is now running one of the largest CAR-T clinical trial worldwide...” During spring 2016, we decided to focus going forward on We are very confident that our immuno-oncology product the development of our immuno-oncology platform and to candidates will bring groundbreaking treatment options to find a strategic partner to further develop and commercialize cancer patients and we are looking forward to our clinical C-Cure® . data to reflect on the company value, rewarding the hard work of our team but also the trust and support that you, Our CHART-1 Phase III European trial has been saluted Dear Shareholders, have shown for all these years. by leaders in the field as a significant milestone in the understanding of the heart failure disease and also in the Michel Lussier, identification of a well-defined patient population that could Chairman of the Board benefit from C-Cure®. Based on the key learning of this study, the US pivotal trial CHART-2 will incorporate optimized dosing regimens as well as a new FDA-agreed primary endpoint. This new Phase III study is ready to be initiated and Celyad is actively looking for partners to further develop and commercialize C-Cure®, one of the most advanced reparative cell therapy for heart failure worldwide. Yes, we have faced ups and downs – which company doesn’t? – but most importantly, we made the right decisions at the right time, moving on to the next chapter of our company history . 2017 will be a very exciting year for Celyad, which is now running one of the largest CAR-T clinical trials worldwide, targeting more indications than any of its competitors ever did so far. CELYAD • ANNUAL REPORT 2016 05 Letter of the CEO Dear Shareholders, 2016 has been a year in which our CAR-T portfolio matured, where we have increased our expertise in the field of immuno-oncology, and in which we transitioned from being focused on cardiology to being one of the most promising companies in the field of CAR-T cells. The portfolio acquired beginning of 2015 from Dartmouth College’s Prof. Charles Sentman, is one of the most elegant approaches to targeting cancers using CAR-T cells as Prof. Sentman combines the breadth of innate immunity with the potency of T cell mediated activity. Christian Homsy — CHIEF EXECUTIVE OFFICER As many great ideas, the concept is simple, but its power has far reaching implications: One single product candidate, potentially targeting 80% of all cancers, an approach that can be compared to checkpoint inhibitors. Even in challenging animal models, our pre-clinical testing yielded remarkable antitumor activity with the long-term survival of treated animals despite aggressive hematological and solid tumor cancers. This work has uncovered multiple modes of actions in those models, from direct cytotoxicity to adaptive immunity including anti-neoangiogenesis, and immune system modulation. Our Target Product Profile (TPP) is unique. We can highlight two differentiating attributes amongst many others: First, instead of injecting cells that proliferate 06 CELYAD • ANNUAL REPORT 2016 “We are also the only company that has both a lower risk autologous approach, and a higher reward allogeneic development. Should allogeneic yield results similar to what we are seeing in autologous, Celyad will then have an approach to target large indications more cost effectively. Should autologous prevail, we have incredibly creative solutions that reduce the cost of goods to levels unseen before.” in the patient in an uncontrolled way, and attempting to deal We have completed a Phase Ia trial in Acute Myeloid Leukemia with the consequences by inserting control mechanisms, we (AML) and Multiple Myeloma (MM) at the Dana Farber Cancer prefer to use a known pre-defined dose, injected multiple Institute. Top line data were reported last November at ASH. times to provide sufficient persistence. Second, instead of In all doses tested, no targeting of healthy tissues occurred. severely lymphodepleting the patients, we use and leverage Despite the low doses tested, some patients unexpectedly the patient’s own immune system. showed first clinical responses, targeting AML and MM makes us pioneers in these two very severe malignancies. We are also the only company that has both a lower risk autologous approach, and a higher reward allogeneic To conclude the year, we initiated the THINK trial where we development. Should allogeneic yield results similar to what are testing our CAR-T NKR-2 in 7 different indications (two we will be seeing in autologous, Celyad will then have an hematological cancers, AML and MM, and five solid tumors), approach to target large indications more cost effectively. in up to 112 patients, making it one of the largest and most Should autologous prevail, we have incredibly creative comprehensive Phase I programs in the industry! solutions that reduce the cost of goods to levels unseen before. I would like to conclude by thanking first the Celyad employees, who managed to re-orient themselves and On the intellectual property side, our space is clean with demonstrated their capacity to adapt. Perseverance is what no competing technologies. In the allogeneic CAR-T field, differentiates good teams from great teams. I am honored to we hold a patent that, until now, and despite having been serve them as their CEO. I would also like to thank you, our challenged at numerous occasions, grant us broad and shareholders, that, despite the challenges faced in 2016 have robust position in this field. maintained their confidence in your company and its team. The road to breakthrough therapies is made of bumps, but, Our allogeneic technology was vetted by a partnership with for the sake of our patients, we will prevail. one of the pioneers of immuno-oncology, the Japanese Christian Homsy, company ONO Pharmaceuticals, which is at the forefront of Chief Executive Officer of Celyad checkpoint inhibitors invention. CELYAD • ANNUAL REPORT 2016 07 Our Mission Bringing breakthrough pioneering therapies to patients with life- threatening diseases. Celyad is a clinical-stage biopharmaceutical company, focused on the development of specialized cell-based therapies. We are using our expertise in cell engineering to translate landmark technologies into drug candidates aimed at treating severe diseases with signifi- cant unmet needs. 08 CELYAD • ANNUAL REPORT 2016 Key figures 2016 Celyad was founded in 2007 and is based in Mont-Saint- 3 2 Guibert, Belgium, and Boston, Massachusetts stock listings on Euronext technological platforms in Brussels, Paris and NASDAQ immuno-oncology (autologous & allogeneic) 3 1 7 study assets in pre-clinical and Phase I trial completed in cancer indications covered clinical development (CAR-T the US for our CAR-T NKR-2 by our ongoing multinational NKR-2, CAR-T NKR-3 and immuno-oncology program in Phase I THINK trial (bladder, CAR-T B7H6) patients with AML and MM. No colorectal, pancreas, breast, safety issue reported ovarian, AML, MM) 3 CHART-1 international collaborations the European Phase III clinical trial evaluating the with Dartmouth College (USA), efficacy of C-Cure®, our lead cardiology candidate, has Institut Curie (France) and ONO been completed.
Load more

Recommended publications
  • Het Oversteken Van De Vallei Van De Lasne Door De Pruisische Troepen Op 18 Juni 1815
    The passage of the valley of the Lasne by the Prussian units on the 18th of June 1815. According to Von Bülow himself it was the information of major Von Falckenhausen which led Blücher to decide to cross the valley of the Lasne and to occupy the Bois de Paris. 1 Others believe it was major Von Lützow’s information which led Blücher to do so. 2 From shortly before 10 a.m. onwards, Von Lützow had, accompanied by lieutenant Von Massow and a detachment of the 2nd regiment of Silesian hussars (3), observed the positions of Wellington and Napoleon from a covered position in the western edge of the Bois de Paris. 4 Von Lützow reported to Blücher that the Bois de Paris was not occupied and that the French right flank wasn’t secured at all. Before he did so, Von Lützow left lieutenant Von Massow with the hussars behind in the wood. Some patrols had crossed the valley of the Lasne. One of them reported: Der Weg nach La Haye durch Lasne führend geht ziemlich sanft herunter das diesseitige Ufer ist bei weitem steiler. Der Weg ist, so lang das Defilée, mit 20 Fuss hohen Wenden eingeschlossen. … Der Bach der Lasne ist nur unbedeutend 2 bis 3 Fuss tief. [..] Block 5 It was Von Valentini himself, who, accompanied by a farmer and a private called Dieterichs, also acqainted himself with the fact that both the village of Lasne and the Bois de Paris were not occupied by the enemy. 6 After the 2nd regiment of Silesian hussars had entered Chapelle Saint Lambert, it detached one squadron to Lasne to verify whether it was occupied.
    [Show full text]
  • Inbw Calendriers 2021 Lasne
    Calendrier 2021 des collectes de déchets Commune de Lasne Téléchargez gratuitement l’application Recycle! pour tout connaître sur les collectes des déchets. PMC : vous serez averti personnellement lorsqu’il y aura du nouveau pour le sac bleu Ensemble Trions bien Recyclons mieux Janvier Février Mars Avril Mai Juin Juillet Août Septembre Octobre Novembre Décembre PMC 12-26 9-23 9-23 6-20 4-18 1-15-29 13-27 10-24 7-21 5-19 2-16-30 14-28 Papiers-cartons 5 2 2-30 27 25 22 20 17 14 12 9 7 Ordures ménagères Tous les mercredis (le lendemain en cas de jour férié) et organiques Encombrants Enlèvements à la demande (voir au verso) Déchets verts Les samedis 24/04 – 08/05 – 22/05 – 05/06 – 19/06 – 03/07 – 24/07 – 14/08 – 04/09 – 18/09 – 02/10 – 16/10 – 30/10 – 13/11 Pour de plus amples renseignements sur les collectes de déchets, voir au verso. Remarques importantes : Un problème concernant les collectes de déchets ou les bulles à verre ? Contactez in BW (votre intercommunale de gestion des déchets) • Les collectes commencent dès 6 h du matin (5 h en cas de canicule). Prière de sortir vos déchets la veille à partir de 18 h. 0800 49 057 • Placez-les à un endroit bien visible pour les collecteurs. • S’ils n’ont pas été collectés, contactez in BW (0800/49 057 ou valmat@inbw.be valmat@inbw.be) le jour même et laissez vos déchets sur le trottoir jusqu’au soir du jour ouvrable suivant.
    [Show full text]
  • TEC Brabant Wallon
    Aalst Brussegem Borgt Peutie Perk Wijgmaal-kern Houwaart Loksbergen Mollem Delle Kortrijk-Dutsel Grimbergen ¾B Berg ¿ B Molenbeek-Wersbeek Vilvoorde ¾¿ Bollebeek Nederokkerzeel Lignes régulières Putkapel Holsbeek Tielt ¾¿B Asse-Ter-Heide Krokegem Groot Molenveld 35 : Jodoigne - Grez-Doiceau 115 : Braine-l'Alleud - Tubize Parcours principalHamme Variante Tarification HORIZON + Waanrode Erembodegem 10 : Navette de La Hulpe 36 : Braine-l'Alleud - Wavre 116 : Soignies - Braine-le-Comte - Rebecq - Tubize - Halle Steenokkerzeel 11 : Ottignies - Einstein - Fleming 37 : Wavre Gare - Bierges Verseau 3 3 C : Louvain-la-Neuve - Wavre - Ixelles/ElseneMelsbroek 121 : Alsemberg Winderickxplein - Argenteuil Berlaymont Affligem Kobbegem Machelen 14 : Navette de Rixensart 38 : Rosières - Genval - Basse-Wavre 122 : Rhode-Saint-Genèse Clos Fleuri / Kortenaken Cbis : Louvain-la-Neuve - Wavre - Kraainem/CrainhemSTEENOKKERZEEL - Woluwe Asse ¾¿B 15 : Navette de Genval 40 : Uccle/Ukkel - Alsemberg - Braine-l'Alleud Sint-Genius-Rode Bloemenhof - Argenteuil Berlaymont ¾¿B 36 36 Strombeek-Bever Herent Sint-Joris-Winge 16 : Nivelles - Zoning Sud 43 : Tubize - Ittre Prison - Ittre Croiseau 123 : Bruxelles Midi / Brussel Zuid - Argenteuil Berlaymont Asbeek Wemmel Koningslo ¾¿B 17 : Ottignies - Clinique - Petit-Ry 47 : Tubize - Virginal - Ittre Croiseau 124 : Uccle Héros / Ukkel Helden - Argenteuil Berlaymont Veltem-Beisem¾¿B 71 Relegem 71 MACHELEN Attenhoven Kiezegem 1 : Jodoigne - Louvain-la-Neuve - Ottignies Tarification HORIZON + 18 : Leuven - Hamme-Mille - Jodoigne
    [Show full text]
  • Centre Provincial De L'agriculture Et De La Ruralité
    Edition 2016 Ed. Resp. Hervé Champagne, fonctionnaire de l’information – Province du Brbabant wallon, av. Einstein, 2 à 1300 Wavre Centre provincial de l’agriculture et de la ruralité L’agriculture brabançonne wallonne | Edition 2016 Centre provincial de l’agriculture et de la ruralité L’agriculture brabançonne wallonne | Edition 2016 Centre provincial de l’agriculture et de la ruralité 17, rue Saint-Nicolas. 1310 La Hulpe Téléphone : 02 656 09 70 - Télécopieur : 02 652 03 06 agriculture@brabantwallon.be Avec la participation de « Brabant wallon Agro-Qualité asbl » 3 Préambule ......................................................................................................................... 5 1. L’agriculture brabançonne wallonne, les chiffres clés ............................................. 6 2. Statistiques agricoles générales en Brabant wallon ................................................. 8 3. Le Brabant wallon parmi les autres provinces wallonnes ..................................... 9 4. Evolution du nombre d’exploitations agricoles ...................................................... 10 5. Evolution de la superficie agricole utilisée (SAU) ...................................................... 11 6. Superficie, rendements et productions en Brabant wallon...................................... 12 7. Evolution de la taille des exploitations agricoles ........................................................ 13 8. Perspectives de reprises d’exploitation ......................................................................
    [Show full text]
  • Procès Verbal Du Conseil Du 13 Mars 2019
    SEANCE DU 13 MARS 2019 ============== Présents : MM Léon Walry, Bourgmestre - Président Benoît Malevé, Joseph Tordoir, Jean-Pierre Beaumont,Echevins Lucette Degueldre, Echevine; José Letellier, François Ruelle, Colette Prévost, Sarah-Françoise Scharpé, Muriel Flamand, Stéphane Deprez, Sophie Parisse, Annabelle Romain- Flament, Geneviève Flémal-Ottoul, Véronique Laenen-Bousez, Hélène Vuylsteke-De Lannoy, Mathilde Gramme, Conseillers communaux Françoise Legrand, Directeur général. L'ordre du jour a été fixé par le Collège communal en séance du 1er mars 2019. SEANCE PUBLIQUE 1. Marchés publics - Politique d'achats durables. 2. Finances - Budget 2019 - Arrêté du Ministre des Pouvoirs locaux et de la Ville - Prise d’acte. 3. Finances - Consultation de marché - Emprunts suite Budget 2019 - Répétitions de services similaires - Approbation. 4. Finances - Marché de collecte des déchets ménagers inBW - Mode de collecte - Décision 5. Finances - Marché public de services - Préparation et livraison de potages et de repas chauds s'inscrivant dans une démarche d'alimentation durable aux écoles communales du 1er septembre 2019 au 31 août 2022 - Approbation des conditions et du mode de passation. 6. Finances - "Menues dépenses" - Augmentation du fonds de caisse - Ratification. 7. Plan de Cohésion Sociale - Rapport financier 2018 - Approbation. 8. Urbanisme - Refus de permis - Dossier Intervention de la commune à la cause - Ratification. 9. Urbanisme - Projet d'acte de cession d'une partie de parcelle cadastrée à Glimes pour cause d'utilité publique - Pour accord. 10. Patrimoine - Echange de parcelles à Opprebais - Accord de principe - Ratification. 1 11. Travaux - Marché public de fournitures - Rénovation et mise en place d'un système de chauffage à l'église d'Opprebais - Mode et conditions de passation du marché - Approbation.
    [Show full text]
  • Court-Saint-Etienne Plan Communal De Mobilité Phase 3
    Court-Saint-Etienne Plan Communal de Mobilité Phase 3 - Plan d'action 14 février 2011 Association momentanée En collaboration avec Tables des matières 1 INTRODUCTION..............................................................................................................3 1.1 Rappel des objectifs du PCM .................................................................................................................... 3 1.2 Le présent document................................................................................................................................. 4 2 AMENAGEMENT DU TERRITOIRE ................................................................................5 3 LE RESEAU ROUTIER....................................................................................................6 3.1 Hiérarchisation du réseau.......................................................................................................................... 6 3.2 Le centre de Court-Saint-Etienne ............................................................................................................ 10 3.3 Gestion des vitesses ............................................................................................................................... 13 3.4 Principes d'aménagement des routes régionales .................................................................................... 15 3.5 Modération de la vitesse.........................................................................................................................
    [Show full text]
  • Relive and Refight the Battle of Waterloo CONTENTS
    For 2 Players Ages 12 & Up ® Rules of the game Relive and refight the battle of Waterloo www.stratego.com CONTENTS INTRO 2 PART II CONTENTS 2 STANDARD GAME 7 THE GAME 2 10. TERRAIN TILES 7 11. MANEUVER CARDS 8 PART I THE BASICS 3 PART III 1. WINNING THE GAME 3 EXPERT GAME 9 2. SET-UP 3 12. PLANCENOIT 9 3. LINES OF RETREAT 3 13. THE PURSUIT 10 4. THE PIECES 4/5 14. EXTRA SCENARIOS 10/11 5. THE COMMANDERS 5 GAME PIECES 12/13 6. ARMY SET UP 5 7. MOVEMENT 6 8. ATTACK 6 9. THE PRUSSIANS ARRIVE! 6 ® “Napoleon regained his Empire by simply showing his Hat.” Quote from Honoré de Balzac. After having ruled over 80 million people, subdued the greater CONTENTS part of the continent and influenced European politics for almost 20 years, Napoleon Bonaparte, Emperor of the French, was • 47 x Blue Pieces finally driven into exile in April 1814 by the armies of Austria, • 45 x Red Pieces Prussia and Russia. From his island on Elba off the Italian coast, • 13 x Black Pieces he watched France under the restored Bourbon monarchy writhe • 1 x Game Board in confusion and unrest. In February 1815, convinced that the • 1 x Battle Die army would fight for him as they had done in the past from the hot • 2 x Hill Tiles sands of Egypt to the cold snows of Russia, Napoleon escaped and • 2 x Mud Tiles returned to France. The leaders of the European powers, gathered • 3 x Building Tiles at the Congress of Vienna, swore no peace with Bonaparte, • 15 x Maneuver Cards branded him an outlaw and hurried to take up arms again.
    [Show full text]
  • Le Brabant Wallon En Chiffres Fondation Economique Et Sociale Du Brabant Wallon
    EDITION 2017 LE BRABANT WALLON EN CHIFFRES FONDATION ECONOMIQUE ET SOCIALE DU BRABANT WALLON LE BRABANT WALLON EN CHIFFRES | 01 TABLE LA PROVINCE DU BRABANT WALLON DES MATIÈRES EN QUELQUES DONNÉES La Province du Brabant wallon Beauvechain en quelques données 03 Hélécine Grez-Doiceau La Hulpe Introduction 04 Jodoigne Waterloo Rixensart Wavre Chapitre 1 : Population 06 Chaumont- Gistoux Orp-Jauche Tubize Incourt Braine-le- Lasne Château Braine- l’Alleud Ottignies-LLN Chapitre 2 : Niveau de vie 16 Rebecq Mont- Ramillies Ittre St-Guibert Perwez Chapitre 3 : Enseignement et formation 24 Court- Walhain St-Etienne Genappe Chapitre 4 : Emploi et chômage 40 Nivelles Chastre Chapitre 5 : Activité économique 47 Villers-la-Ville Chapitre 6 : Activités et entreprises 58 Chapitre 7 : Occupation du territoire et prix 64 Annexe Top 100 des entreprises du Brabant wallon La Province du Brabant wallon c’est : au niveau de l’emploi localisé 71 • Une des 5 provinces de la Wallonie. • Un seul arrondissement judiciaire et administratif qui regroupe 27 communes dont Wavre est le chef-lieu. • Un territoire d’une superficie de 1.091 km2 (soit 3,6% du territoire national et 6,5% du territoire wallon). • Une population de 396.840 habitants au 1er janvier 2016. • Une situation géographique privilégiée au cœur de l’Europe : • limitrophe de Bruxelles, capitale européenne • voisine de la Région flamande • traversée par ou à proximité des grands axes autoroutiers et ferroviaires : E411, E40, E19, A8, N25 et les lignes 124, 140, 161 renforcées par le futur RER • Un cadre de vie et de travail agréable et diversifié. • Une fiscalité, pour certaines communes, parmi les plus basses de Wallonie .
    [Show full text]
  • Votre Commune En Chiffres: Court-Saint-Etienne
    Votre commune en chiffres: Court-Saint-Etienne Votre commune en chiffres: Court-Saint-Etienne SPF Economie, DG Statistique et information ´economique SPF Economie, DG Statistique et information ´economique Votre commune en chiffres: Court-Saint-Etienne Votre commune en chiffres: Court-Saint-Etienne Introduction Court-Saint-Etienne : Court-Saint-Etienne est une commune de la province de Brabant wallon et fait partie de la R´egion wallonne. Ses communes voisines sont Chastre, Genappe, Mont-Saint-Guibert, Ottignies-Louvain-la-Neuve et Villers-la-Ville. Court-Saint-Etienne a une superficie de 26,6 km2 et compte 9.943 ∗ habitants, soit une densit´ede 373,2 habitants par km2. 63% ∗ de sa population a entre 18 et 64 ans. Parmi les 589 communes belges, elle se situe `ala 139`eme y place par rapport au revenu moyen net par habitant le plus ´elev´eet `ala 344`eme z place par rapport aux prix des terrains `ab^atir les plus chers. ∗. Situation au 1/1/2011 y. Revenus de l'ann´ee2009 - Exercice d'imposition 2010 z. Ann´eede r´ef´erence : 2011 SPF Economie, DG Statistique et information ´economique Votre commune en chiffres: Court-Saint-Etienne Votre commune en chiffres: Court-Saint-Etienne Table des mati`eres 1 Table des mati`eres 2 Population Composition de la population Pyramide des ^ages pour Court-Saint-Etienne 3 Territoire Densit´ede population pour Court-Saint-Etienne et ses communes limitrophes Occupation du sol 4 Immobilier Prix des terrains `ab^atir en Belgique Prix des terrains `ab^atir pour Court-Saint-Etienne et environs Prix des terrains `ab^atir
    [Show full text]
  • 'No Troops but the British': British National Identity and the Battle For
    ‘No Troops but the British’: British National Identity and the Battle for Waterloo Kyle van Beurden BA/BBus (Accy) (QUT), BA Honours (UQ) A thesis submitted for the degree of Master of Philosophy at The University of Queensland in 2015 School of Historical and Philosophical Inquiry British National Identity and the Battle for Waterloo Kyle van Beurden Abstract In the ‘long eighteenth-century’ British national identity was superimposed over pre-existing identities in Britain in order to bring together the somewhat disparate, often warring, states. This identity centred on war with France; the French were conceptualised as the ‘other’, being seen by the British as both different and inferior. For many historians this identity, built in reaction and opposition to France, dissipated following the defeat of Napoleon at Waterloo in 1815, as Britain gradually introduced changes that allowed broader sections of the population to engage in the political process. A new militaristic identity did not reappear in Britain until the 1850s, following the Crimean War and the Indian Mutiny. This identity did not fixate on France, but rather saw all foreign nations as different and, consequently, inferior. An additional change was the increasing public interest in the army and war, more generally. War became viewed as a ‘pleasurable endeavour’ in which Britons had an innate skill and the army became seen as representative of that fact, rather than an outlet to dispose of undesirable elements of the population, as it had been in the past. British identity became increasingly militaristic in the lead up to the First World War. However, these two identities have been seen as separate phenomena, rather than the later identity being a progression of the earlier construct.
    [Show full text]
  • Inventaire Des Archives De L'arrondissement PSC De Nivelles
    INVENTAIRE RÉALISÉ PAR : TABLE DES MATIÈRES Table des matières ...................................................................................................................... 1 Description générale du fonds .................................................................................................... 3 A. Identification ..................................................................................................................... 3 B. Histoire du producteur et des archives .............................................................................. 3 B.I. Histoire du producteur ................................................................................................. 3 B.II. Histoire des archives .................................................................................................. 4 C. Contenu et structure ........................................................................................................... 4 C.I. Contenu ....................................................................................................................... 4 C.II. Sélection et élimination .............................................................................................. 5 C.III. Accroissement .......................................................................................................... 5 C.IV. Mode de classement ................................................................................................. 5 D. Consultation et utilisation .................................................................................................
    [Show full text]
  • Une Boucle Pédestre De 38 Km Pour Relier L'abbaye De Villers-La-Ville À
    www.globaldesign.be 2015 Février : Edition – D/2015/10.966/3 : légal Dépôt Stéphane Colin, Président - MTPVBW - Président Colin, Stéphane Une boucle pédestre de 38 km pour relier l’Abbaye de Villers-la-Ville à la Butte du Lion dit de Waterloo. Editeur responsable : : responsable Editeur P Cette boucle peut être entreprise tant depuis Waterloo que depuis Villers-la-Ville. R1 à R5 3 P P P Elle permet de découvrir des villages et leur patrimoine historique, P 1 2 4 9 parcourir chemins et sentiers, apprécier H3 la beauté des paysages champêtres. R0R P et de la Province du Brabant wallon Brabant du Province la de et 8 Cette balade off re une belle occasion de Avec le soutien du Commissariat général au Tourisme de Wallonie de Tourisme au général Commissariat du soutien le Avec N5 Chaussée de Charleroi Couture H5 Saint-Germain (re)découvrir le patrimoine naturel, P Donnez-nous votre feedback après votre balade ! ! balade votre après feedback votre Donnez-nous bâti et rural de toute beauté de P 7 6 cette région du Brabant wallon. www.waterloo-tourisme.com info@waterloo-tourisme.be info@waterloo-tourisme.be P Non accessible aux Tél. +32 (0)2 352 09 10 09 352 (0)2 +32 Tél. 5 poussettes/buggies. 218 chaussée de Bruxelles - 1410 Waterloo 1410 - Bruxelles de chaussée 218 Maison du Tourisme de Waterloo de Tourisme du Maison H4 R7 Maransart sur votre smartphone ou votre tablette. votre ou smartphone votre sur N5 ou via l’appli «Rando Around Villers-la-Ville» Villers-la-Ville» Around «Rando l’appli via ou Plancenoit www.paysdevillers-tourisme.be - onglet «Bouger» (format pdf) pdf) (format «Bouger» onglet - www.paysdevillers-tourisme.be Découvrez et téléchargez gratuitement d’autres balades sur sur balades d’autres gratuitement téléchargez et Découvrez Hébergements situés à moins de 5 km du circuit www.facebook.com/paysdevillers www.facebook.com/paysdevillers (H1-H2-H3-H7-H8-H9 : hors carte) www.paysdevillers-tourisme.be Les hébergements repris ici sont situés à moins de 5 km du circuit.
    [Show full text]